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Metabolic Pathways
Pathway Projector (zoomable user interface for systems biology)
Metabolic Pathway Links in "ExPASy":
the digitized version of the Roche Applied Science "Biochemical Pathways" wall chart
[view entire chart as thumbnails]
- Cholesterol Metabolism (Images G10 & H10)
Cholesterol ----> 7a-Hydroxycholesterol
7a-Hydroxycholesterol <---> 7a,12a-Dihydroxycholest-4-en-3-one
Cholesterol ---> D4-Cholesten-3-on
Cholesterol ---> Coprostanol
Cholesterol ---> Cholesterol Ester
Cholesterol ---> 22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
- Cholesterol Metabolism (Images H10 & I10)
7a-Hydroxycholesterol <---> 7a,12a-Dihydroxycholest-4-en-3-one
7a,12a-Dihydroxycholest-4-en-3-one ---> 7a,12a-Dihydroxy-5B-cholestan-3-one
7a,12a-Dihydroxycholest-4-en-3-one ---> 7a-Hydroxy-5B-cholestan-3-one
22B-Hydroxycholesterol ---> 20a,22B-Dihydroxycholesterol
22B-Hydroxycholesterol ---> 17a,20a-Dihydroxycholesterol
- Bile Acid Synthesis (Images I10 & J10)
7a,12a-Dihydroxy-5B-cholestan-3-one <---> 3a,7a,12a-Trihydroxy-5B-cholestane
3a,7a,12a-Trihydroxy-5B-cholestane ----> 3a,7a,12a,26-Tetrahydroxy-5B-cholestane
7a-Hydroxy-5B-cholestan-3-one ---> 3a,7a-Dihydroxy-5B-cholestane
3a,7a-Dihydroxy-5B-cholestane ---> Chenodeoxycholate
- Bile Acid Synthesis (Images J10 & K10)
3a,7a,12a,26-Tetrahydroxy-5B-cholestane <---> 3a,7a,12a,-Trihydroxy-5B-cholestaoate
3a,7a,12a-Trihydroxy-5B-cholestanoate ---> ---> Choloyl-CoA
3a,7a,12a,26-Tetrahydroxy-5B-cholestanoate ---> 5B-Cyprinolsulfate
5B-Cyprinolsulfate ---> Scymnol Sulfate
- Bile Acid Synthesis (Images K10 & L10)
Choloyl-CoA <---> Cholate
Choloyl-CoA ---> Taurocholate
Choloyl-CoA ---> Glycocholate
Taurocholate <---> Cholate
Glycocholate <---> Cholate
Cholate ---> ---> Deoxycholate
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David and Judy Rhodes
Last Update: 11/28/09
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