|
|
|
Scientific Literature, gene expression
-
Aaltonen J, Bjorses P. Cloning of the APECED gene provides new insight into human autoimmunity.
Ann. Med. 31: 111-116 (1999).
-
Abal M, Obrador-Hevia A, Janssen KP, Casadome L, Menendez M, Carpentier S, Barillot E, Wagner M, Ansorge W, Moeslein G, Fsihi H, Bezrookove V, Reventos J, Louvard D, Capella G, Robine S. APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation.
Gastroenterology 132: 2448-2458 (2007).
*
-
Abarrategui I, Krangel MS. Germline transcription: a key regulator of accessibility and recombination.
Adv. Exp. Med. Biol. 650: 93-102 (2009).
-
Abate N, Chandalia M, Di Paola R, Foster DW, Grundy SM, Trischitta V. Mechanisms of disease: ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors.
Nat. Clin. Pract. Endocrinol. Metab. 2: 694-701 (2006).
*
-
Abba MC, Hu Y, Levy CC, Gaddis S, Kittrell FS, Zhang Y, Hill J, Bissonnette RP, Medina D, Brown PH, Aldaz CM. Transcriptomic signature of the chemopreventive bexarotene (rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models.
BMC Med. Genomics 1: 40 (2008).
*
-
Abbas AR, Baldwin D, Ma Y, Ouyang W, Gurney A, Martin F, Fong S, van Lookeren Campagne M, Godowski P, Williams PM, Chan AC, Clark HF. Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data.
Genes Immun. 6: 319-331 (2005).
*
-
Abbas AR, Wolslegel K, Seshasayee D, Modrusan Z, Clark HF. Deconvolution of blood microarray data identifies cellular activation patterns in systemic lupus erythematosus.
PLoS One 4: e6098 (2009).
*
-
Abbas S, Brauch H, Chang-Claude J, Dunnebier T, Flesch-Janys D, Hamann U, Hein R, Justenhoven C, Salazar R. Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy.
Int. J. Cancer Sep 8 [Epub ahead of print] (2009).
*
-
Abbasi AM, Chester KA, MacPherson AJ, Boxer GM, Begent RH, Malcolm AD. Localization of CEA messenger RNA by in situ hybridization in normal colonic mucosa and colorectal adenocarcinomas.
J. Pathol. 168: 405-411 (1992).
-
Abbey JL, O'Neill HC. Expression of T-cell receptor genes during early T-cell development.
Immunol. Cell Biol. 86: 166-174 (2008).
*
-
Abbott BD. Review of the expression of peroxisome proliferators activated receptors alpha (PPARalpha), beta (PPARbeta), and gamma (PPARgamma) in rodent and human development.
Reprod. Toxicol. 27: 246-257 (2009).
-
Abbott BD, Wolf CJ, Schmid JE, Das KP, Zehr RD, Helfant L, Nakayama S, Lindstrom AB, Strynar MJ, Lau CS. Perfluorooctanoic acid (PFOA)-induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha (PPARalpha).
Toxicol. Sci. 98: 571-581 (2007).
*
-
Abd El-Ghaffar HA, Aladle DA, Farahat SE, Abd El-Hady N. P-Glycoprotein (P-170) expression in acute leukemias.
Hematology 11: 35-41 (2006).
-
Abdelmalek MF, Liu C, Shuster J, Nelson DR, Asal NR. Familial aggregation of insulin resistance in first-degree relatives of patients with nonalcoholic fatty liver disease.
Clin. Gastroenterol. Hepatol. 4: 1162-1169 (2006).
-
Abdeltawab NF, Aziz RK, Kansal R, Rowe SL, Su Y, Gardner L, Brannen C, Nooh MM, Attia RR, Abdelsamed HA, Taylor WL, Lu L, Williams RW, Kotb M. An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis.
PLoS Pathog. 4: e1000042 (2008).
*
-
Abdgawad M, Hellmark T, Gunnarsson L, Westman KW, Segelmark M. Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism.
Clin. Exp. Immunol. 145: 63-70 (2006).
*
-
Abdollahi-Roodsaz S, Joosten LA, Koenders MI, van den Brand BT, van de Loo FA, van den Berg WB. Local interleukin-1 driven joint pathology is dependent on Toll-like receptor 4 activation.
Am. J. Pathol. 175: 2004-2013 (2009).
*
-
Abdollahi-Roodsaz S, Joosten LA, Roelofs MF, Radstake TR, Matera G, Popa C, van der Meer JW, Netea MG, van den Berg WB. Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis.
Arthritis Rheum. 56: 2957-2967 (2007).
*
-
Abdou AG, Hanout HM. Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study.
J. Cutan. Pathol. 35: 445-451 (2008).
*
-
Abdulahad WH, van der Geld YM, Stegeman CA, Kallenberg CG. Persistent expansion of CD4(+) effector memory T cells in Wegener's granulomatosis.
Kidney Int. 70: 938-947 (2006).
*
-
Abdulrahman W, Uhring M, Kolb-Cheynel I, Garnier JM, Moras D, Rochel N, Busso D, Poterszman A. A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies.
Anal. Biochem. 385: 383-385 (2009).
*
-
Abe K, Klaften M, Narita A, Kimura T, Imai K, Kimura M, Rubio-Aliaga I, Wagner S, Jakob T, Hrabe de Angelis M. Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice.
Mamm. Genome 20: 152-161 (2009).
*
-
Abe R, Yamagishi SI, Fujita Y, Hoshina D, Sasaki M, Nakamura K, Matsui T, Shimizu T, Bucala R, Shimizu H. Topical application of anti-angiogenic peptides based on pigment epithelium-derived factor can improve psoriasis.
J. Dermatol. Sci. Jan 7 [Epub ahead of print] (2010).
-
Abe S, Hanawa H, Hayashi M, Yoshida T, Komura S, Watanabe R, Lie H, Chang H, Kato K, Kodama M, Maruyama H, Nakazawa M, Miyazaki J, Aizawa Y. Prevention of experimental autoimmune myocarditis by hydrodynamics-based naked plasmid DNA encoding CTLA4-Ig gene delivery.
J. Card. Fail. 11: 557-564 (2005).
-
Abebe F, Mustafa T, Nerland AH, Bjune GA. Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease.
Clin. Exp. Immunol. 143: 180-192 (2006).
*
-
Abebe M, Doherty TM, Wassie L, Aseffa A, Bobosha K, Demissie A, Zewdie M, Engers H, Andersen P, Kim L, Huggett J, Rook G, Yamuah LK, Zumla A; the VACSEL study group. Expression of apoptosis-related genes in an Ethiopian cohort study correlates with tuberculosis clinical status.
Eur. J. Immunol. Oct 28 [Epub ahead of print] (2009).
*
-
Abedin SA, Banwell CM, Colston KW, Carlberg C, Campbell MJ. Epigenetic corruption of VDR signalling in malignancy.
Anticancer Res. 26: 2557-2566 (2006).
-
Abedin SA, Thorne JL, Battaglia S, Maguire O, Hornung L, Doherty AP, Mills IG, Campbell MJ. Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells.
Carcinogenesis 30: 449-456 (2009).
*
-
Abel S, Hundhausen C, Mentlein R, Schulte A, Berkhout TA, Broadway N, Hartmann D, Sedlacek R, Dietrich S, Muetze B, Schuster B, Kallen KJ, Saftig P, Rose-John S, Ludwig A. The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10.
J. Immunol. 172: 6362-6372 (2004).
*
-
Abel S, Yang Y, Waring JF. Development of an in vitro gene expression assay for predicting hepatotoxicity.
ALTEX 23: S326-S331 (2006).
-
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sanchez E, Velazquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy P, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N, Abderrahim H, Pons-Estel BA, Gutierrez C, Suarez A, et al. STAT4 associates with systemic lupus erythematosus through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk.
Ann. Rheum. Dis. 68: 1746-1753 (2009).
-
Aberle J, Flitsch J, Beck NA, Mann O, Busch P, Peitsmeier P, Beil FU. Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes.
Mol. Genet. Metab. 95: 188-191 (2008).
*
-
Abeywardena MY, Head RJ. Longchain n-3 polyunsaturated fatty acids and blood vessel function.
Cardiovasc. Res. 52: 361-371 (2001).
*
-
Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks VW, Bakker AH, Ramaekers FC, De Vente J, Groen AK, Wellington CL, Kuipers F, Mulder M. 24(S)-Hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux.
J. Biol. Chem. 281: 12799-12808 (2006).
*
-
Abiru N, Kawasaki E, Eguch K. Current knowledge of Japanese type 1 diabetic syndrome.
Diabetes Metab. Res. Rev. 18: 357-366 (2002).
*
-
Abo T, Ohteki T, Seki S, Koyamada N, Yoshikai Y, Masuda T, Rikiishi H, Kumagai K. The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria.
J. Exp. Med. 174: 417-424 (1991).
*
-
Abou El-Ela M, Nagui N, Mahgoub D, El-Eishi N, Fawzy M, El-Tawdy A, Abdel Hay R, Rashed L. Expression of cyclin D1 and p16 in psoriasis before and after phototherapy.
Clin. Exp. Dermatol. Jan 18 [Epub ahead of print] (2010).
*
-
Aboul-Enein F, Weiser P, Hoftberger R, Lassmann H, Bradl M. Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis.
Acta Neuropathol. (Berl.) 111: 539-547 (2006).
-
Abraham C, Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease.
Inflamm. Bowel Dis. 15: 1090-1100 (2009).
*
-
Abraham DJ, Varga J. Scleroderma: from cell and molecular mechanisms to disease models.
Trends Immunol. 26: 587-595 (2005).
*
-
Abraham LJ, Kroeger KM. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease.
J. Leukoc. Biol. 66: 562-566 (1999).
*
-
Abraira VE, Satoh T, Fekete DM, Goodrich LV. Vertebrate Lrig3-ErbB interactions occur in vitro but are unlikely to play a role in Lrig3-dependent inner ear morphogenesis.
PLoS One 5: e8981 (2010).
*
-
Abrantes EF, Pires EG, Carvalho AF, Costa FF, Savino W, Reis LF. Identification, structural characterization, and tissue distribution of Tsg-5: a new TNF-stimulated gene.
Genes Immun. 4: 298-311 (2003).
*
-
Abreu JR, Grabiec AM, Krausz S, Spijker R, Burakowski T, Maslinski W, Eldering E, Tak PP, Reedquist KA. The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling.
J. Immunol. 183: 621-630 (2009).
-
Abreu MT. Immunologic regulation of Toll-like receptors in gut epithelium.
Curr. Opin. Gastroenterol. 19: 559-564 (2003).
-
Abreu MT. The pathogenesis of inflammatory bowel disease: translational implications for clinicians.
Curr. Gastroenterol. Rep. 4: 481-489 (2002).
-
Abreu MT, Arnold ET, Thomas LS, Gonsky R, Zhou Y, Hu B, Arditi M. TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells.
J. Biol. Chem. 277: 20431-20437 (2002).
*
-
Abreu MT, Plevy S, Sands BE, Weinstein R. Selective leukocyte apheresis for the treatment of inflammatory bowel disease.
J. Clin. Gastroenterol. 41: 874-888 (2007).
-
Abreu MT, Taylor KD, Lin YC, Hang T, Gaiennie J, Landers CJ, Vasiliauskas EA, Kam LY, Rojany M, Papadakis KA, Rotter JI, Targan SR, Yang H. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease.
Gastroenterology 123: 679-688 (2002).
*
-
Abreu MT, Yang H. Is genetic testing in IBD ready for prime time?
Am. J. Gastroenterol. 99: 316-318 (2004).
*
-
Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures.
Genes Dev. 15: 226-240 (2001).
*
-
Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dolle P. Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis.
Mech. Dev. 110: 173-177 (2002).
*
-
Acevedo-Suarez CA, Hulbert C, Woodward EJ, Thomas JW. Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes.
J. Immunol. 174: 827-833 (2005).
*
-
Achiron A, Gurevich M, Snir Y, Segal E, Mandel M. Zinc-ion binding and cytokine activity regulation pathways predicts outcome in relapsing-remitting multiple sclerosis.
Clin. Exp. Immunol. 149: 235-242 (2007).
*
-
Achkar JP, Dassopoulos T, Silverberg MS, Tuvlin JA, Duerr RH, Brant SR, Siminovitch K, Reddy D, Datta LW, Bayless TM, Zhang L, Barmada MM, Rioux JD, Steinhart AH, McLeod RS, Griffiths AM, Cohen Z, Yang H, Bromfield GP, Schumm P, Hanauer SB, Cho JH, et al. Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus.
Am. J. Gastroenterol. 101: 572-580 (2006).
*
-
Achkar JP, Duerr R. The expanding universe of inflammatory bowel disease genetics.
Curr. Opin. Gastroenterol. 24: 429-434 (2008).
*
-
Ackerman LS. Sex hormones and the genesis of autoimmunity.
Arch. Dermatol. 142: 371-376 (2006).
*
-
Ackert-Bicknell C, Rosen C. The genetics of PPARG and the skeleton.
PPAR Res. 2006: 93258 (2006).
*
-
Acton JD, Wilmott RW. Phenotype of CF and the effects of possible modifier genes.
Paediatr. Respir. Rev. 2: 332-339 (2001).
-
Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S. Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein.
Mol. Cell. Biol. 26: 9003-9015 (2006).
*
-
Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ. PPARgamma in colonic epithelial cells protects against experimental inflammatory bowel disease.
Gut 55: 1104-1113 (2006).
*
-
Adachi T, Toishi T, Takashima E, Hara H. Infliximab neutralizes the suppressive effect of TNF-alpha on expression of extracellular-superoxide dismutase in vitro.
Biol. Pharm. Bull. 29: 2095-2098 (2006).
*
-
Adam R, Sturrock RD, Gracie JA. TLR4 mutations (Asp299Gly and Thr399Ile) are not associated with ankylosing spondylitis.
Ann. Rheum. Dis. 65: 1099-1101 (2006).
*
-
Adam-Stitah S, Penna L, Chambon P, Rochette-Egly C. Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases.
J. Biol. Chem. 274: 18932-18941 (1999).
*
-
Adamiec R, Gacka M, Dobosz T, Szymaniec S, Bednarska-Chabowska D, Sadakierska-Chudy A. Stimulation of the peroxisome proliferator-activated receptor gamma (PPARgamma) and the expression of selected blood monocyte cytokine genes in diabetic macroangiopathy.
Atherosclerosis 194: e108-e115 (2007).
-
Adamkiewicz J, Kaddatz K, Rieck M, Wilke B, Muller-Brusselbach S, Muller R. Proteomic profile of mouse fibroblasts with a targeted disruption of the peroxisome proliferator activated receptor-beta/delta gene.
Proteomics 7: 1208-1216 (2007).
*
-
Adamo KB, Dent R, Langefeld CD, Cox M, Williams K, Carrick KM, Stuart JS, Sundseth SS, Harper ME, McPherson R, Tesson F. Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response.
Obesity (Silver Spring) 15: 1068-1075 (2007).
*
-
Adamopoulos AB. Inflammatory bowel disease (IBD) and the liver.
Annals of Gastroenterology 19: 146-151 (2006). *
-
Adams DH. Mucosal lymphocytes in the pathogenesis of the hepatic complications of inflammatory bowel disease.
Clin. Med. 8: 28-29 (2008).
*
-
Adams DH, Afford SC. Effector mechanisms of nonsuppurative destructive cholangitis in graft-versus-host disease and allograft rejection.
Semin. Liver Dis. 25: 281-297 (2005).
-
Adams DH, Eksteen B, Grant A, Miles A, Lalor T. The molecular regulation of lymphocyte homing between the liver and gut.
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 54 (2005). *
-
Adams M, Lucock M, Stuart J, Fardell S, Baker K, Ng X. Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism.
Neurosci. Lett. 422: 24-29 (2007).
-
Adams PC. Hemochromatosis.
Clin. Liver Dis. 8: 735-753, vii (2004).
-
Adams PC, Walker AP, Acton RT. A primer for predicting risk of disease in HFE-linked hemochromatosis.
Genet. Test. 5: 311-316 (2001).
-
Adamson AW, Dreesen TD, Tekle M, Tang C, Cho HP, Clarke SD, Gettys TW. A newly discovered member of the fatty acid desaturase gene family: a non-coding, antisense RNA gene to Delta5-desaturase.
Prostaglandins Leukot. Essent. Fatty Acids 75: 97-106 (2006).
*
-
Adamson KA, Pearce SH, Lamb JR, Seckl JR, Howie SE. A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues.
J. Pathol. 202: 180-187 (2004).
*
-
Adamzik M, Frey UH, Bitzer K, Jakob H, Baba HA, Schmieder RE, Schneider MP, Heusch G, Peters J, Siffert W. A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men.
Basic Res. Cardiol. 103: 598-610 (2008).
-
Adarichev VA, Vermes C, Hanyecz A, Ludanyi K, Tunyogi-Csapo M, Finnegan A, Mikecz K, Glant TT. Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis.
Autoimmunity 39: 663-673 (2006).
-
Adarichev VA, Vermes C, Hanyecz A, Mikecz K, Bremer EG, Glant TT. Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation.
Arthritis Res. Ther. 7: R196-R207 (2005).
*
-
Adcock IM, Barnes PJ. Molecular mechanisms of corticosteroid resistance.
Chest 134: 394-401 (2008).
*
-
Adcock IM, Caramori G. Cross-talk between pro-inflammatory transcription factors and glucocorticoids.
Immunol. Cell Biol. 79: 376-384 (2001).
*
-
Adcock IM, Ito K, Barnes PJ. Histone deacetylation: an important mechanism in inflammatory lung diseases.
COPD 2: 445-455 (2005).
-
Ademokun A, Turner M. Regulation of B-cell differentiation by microRNAs and RNA-binding proteins.
Biochem. Soc. Trans. 36: 1191-1193 (2008).
*
-
Adib-Conquy M, Pedron T, Petit-Bertron AF, Tabary O, Corvol H, Jacquot J, Clement A, Cavaillon JM. Neutrophils in cystic fibrosis display a distinct gene expression pattern.
Mol. Med. 14: 36-44 (2008).
*
-
Adibi SA. Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease.
Am. J. Physiol. Gastrointest. Liver Physiol. 285: G779-G788 (2003).
*
-
Adida A, Spener F. Adipocyte-type fatty acid-binding protein as inter-compartmental shuttle for peroxisome proliferator activated receptor gamma agonists in cultured cell.
Biochim. Biophys. Acta 1761: 172-181 (2006).
*
-
Adisen E, Gulekon A, Erdem O, Dursun A, Gurer M. The effects of calcipotriol and methylprednisolone aseponate on bcl-2, p53 and ki-67 expression in psoriasis.
J. Eur. Acad. Dermatol. Venereol. 20: 527-533 (2006).
*
-
Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade.
Cell Cycle 7: 556-559 (2008).
*
-
Adler EM. IL-2 antagonizes Th17 differentiation.
Sci. STKE 379: tw103 (2007).
-
Adriaansen J, Fallaux FJ, de Cortie CJ, Vervoordeldonk MJ, Tak PP. Local delivery of beta interferon using an adeno-associated virus type 5 effectively inhibits adjuvant arthritis in rats.
J. Gen. Virol. 88: 1717-1721 (2007).
*
-
Adriaansen J, Khoury M, de Cortie CJ, Fallaux FJ, Bigey P, Scherman D, Gould DJ, Chernajovsky Y, Apparailly F, Jorgensen C, Vervoordeldonk MJ, Tak P. Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent.
Ann. Rheum. Dis. 66: 1143-1150 (2007).
*
-
Adriaansen J, Kuhlman RR, Holten JV, Kaynor C, Vervoordeldonk MJ, Tak PP. Intraarticular interferon-beta gene therapy ameliorates adjuvant arthritis in rats.
Hum. Gene Ther. 17: 985-996 (2006).
-
Adriaansen J, Tas SW, Klarenbeek PL, Bakker AC, Apparailly F, Firestein GS, Jorgensen C, Vervoordeldonk MJ, Tak PP. Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy.
Ann. Rheum. Dis. 64: 1677-1684 (2005).
*
-
Adriaansen J, Vervoordeldonk MJ, Tak PP. Gene therapy as a therapeutic approach for the treatment of rheumatoid arthritis: innovative vectors and therapeutic genes.
Rheumatology (Oxford) 45: 656-668 (2006).
*
-
Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome.
Clin. Immunol. 124: 41-48 (2007).
*
-
Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is down-regulated by interleukin-1beta in articular chondrocytes.
Arthritis Res. Ther. 9: R31 (2007).
*
-
Aflatoonian R, Tuckerman E, Elliott SL, Bruce C, Aflatoonian A, Li TC, Fazeli A. Menstrual cycle-dependent changes of Toll-like receptors in endometrium.
Hum. Reprod. 22: 586-593 (2007).
-
Afman L, Muller M. Nutrigenomics: from molecular nutrition to prevention of disease.
J. Am. Diet. Assoc. 106: 569-576 (2006).
-
Agalliu I, Suuriniemi M, Prokunina-Olsson L, Johanneson B, Collins FS, Stanford JL, Ostrander EA. Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study.
Prostate 68: 740-747 (2008).
-
Agarwal K, Czaja AJ, Donaldson PT. A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis.
Tissue Antigens 69: 227-235 (2007).
*
-
Agarwal P, Raghavan A, Nandiwada SL, Curtsinger JM, Bohjanen PR, Mueller DL, Mescher MF. Gene regulation and chromatin remodeling by IL-12 and type I IFN in programming for CD8 T cell effector function and memory.
J. Immunol. 183: 1695-1704 (2009).
-
Agarwal RK, Horai R, Viley AM, Silver PB, Grajewski RS, Bo Su S, Yazdani AT, Zhu W, Kronenberg M, Murray PJ, Rutschman RL, Chan CC, Caspi RR. Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms.
J. Immunol. 180: 5423-5429 (2008).
*
-
Agassandian M, Miakotina OL, Andrews M, Mathur SN, Mallampalli RK. P. aeruginosa and sPLA2 IB stimulate ABCA1-mediated phospholipid efflux via ERK-activation of PPARalpha/RXR.
Biochem. J. 403: 409-420 (2007).
*
-
Agematsu K, Futatani T, Hokibara S, Kobayashi N, Takamoto M, Tsukada S, Suzuki H, Koyasu S, Miyawaki T, Sugane K, Komiyama A, Ochs HD. Absence of memory B cells in patients with common variable immunodeficiency.
Clin. Immunol. 103: 34-42 (2002).
*
-
Agez L, Laurent V, Pevet P, Masson-Pevet M, Gauer F. Melatonin affects nuclear orphan receptors mRNA in the rat suprachiasmatic nuclei.
Neuroscience 144: 522-530 (2007).
-
Aggad D, Mazel M, Boudinot P, Mogensen KE, Hamming OJ, Hartmann R, Kotenko S, Herbomel P, Lutfalla G, Levraud JP. The two groups of zebrafish virus-induced interferons signal via distinct receptors with specific and shared chains.
J. Immunol. 183: 3924-3931 (2009).
-
Aggarwal BB, Sethi G, Nair A, Ichikawa H. Nuclear factor-kB: a holy grail in cancer prevention and therapy.
Current Signal Transduction Therapy 1: 25-52 (2006). *
-
Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link?
Biochem. Pharmacol. 72: 1605-1621 (2006).
*
-
Aggarwal BB, Takada Y, Oommen OV. From chemoprevention to chemotherapy: common targets and common goals.
Expert Opin. Investig. Drugs 13: 1327-1338 (2004).
-
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17.
J. Biol. Chem. 278: 1910-1914 (2003).
*
-
Aggarwal S, Xie MH, Maruoka M, Foster J, Gurney AL. Acinar cells of the pancreas are a target of interleukin-22.
J. Interferon Cytokine Res. 21: 1047-1053 (2001).
-
Agostini C, Cabrelle A, Calabrese F, Bortoli M, Scquizzato E, Carraro S, Miorin M, Beghe B, Trentin L, Zambello R, Facco M, Semenzato G. Role for CXCR6 and its ligand CXCL16 in the pathogenesis of T-cell alveolitis in sarcoidosis.
Am. J. Respir. Crit. Care Med. 172: 1290-1298 (2005).
*
-
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as colon cancer tumor progression marker.
C.R. Biol. 326: 1041-1043 (2003).
-
Agrawal S, Dimitrova N, Prasthani N, Udayakumar K, Sailakshmi S, Sriram S, Manjusha N, Sengupta U. T2D-Db: an integrated platform to study the molecular basis of type 2 diabetes.
BMC Genomics 9: 320 (2008).
*
-
Agrawal S, Srivastava R, Sharma B, Pandya S, Misra R, Aggarwal A. IL1RN*2 allele of IL-1receptor antagonist VNTR polymorphism is associated with susceptibility to anklyosing spondylitis in Indian patients.
Clin. Rheumatol. 27: 573-576 (2008).
*
-
Aguiari G, Varani K, Bogo M, Mangolini A, Vincenzi F, Durante C, Gessi S, Sacchetto V, Catizone L, Harris P, Rizzuto R, Borea PA, Del Senno L. Deficiency of polycystic kidney disease-1 gene (PKD1) expression increases A(3) adenosine receptors in human renal cells: implications for cAMP-dependent signalling and proliferation of PKD1-mutated cystic cells.
Biochim. Biophys. Acta 1792: 531-540 (2009).
*
-
Aguilar RP, Genta S, Oliveros L, Anzulovich A, Gimenez MS, S Sanchez S. Vitamin A deficiency injures liver parenchyma and alters the expression of hepatic extracellular matrix.
J. Appl. Toxicol. 29: 214-222 (2009).
*
-
Aguilar-Martinez P, Bismuth M, Picot MC, Thelcide C, Pageaux GP, Blanc F, Blanc P, Schved JF, Larrey D. Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause?
Gut 48: 836-842 (2001).
*
-
Aguilera O, Pena C, Garcia JM, Larriba MJ, Ordonez-Moran P, Navarro D, Barbachano A, de Silanes IL, Ballestar E, Fraga MF, Esteller M, Gamallo C, Bonilla F, Gonzalez-Sancho JM, Munoz A. The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells.
Carcinogenesis 28: 1877-1884 (2007).
*
-
Aguillon G JC, Cruzat C A, Contreras-Levicoy J, Dotte G A, Pesce R B, Aravena MO, Salazar A L, Catalan M D, Abello C P, Aguirre D A, Llanos M C, Cuchacovich TM. Emergent therapies for rheumatoid arthritis.
Rev. Med. Chil. 133: 969-976 (2005).
-
Aguillon JC, Cruzat A, Aravena O, Salazar L, Llanos C, Cuchacovich M. Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution?
Immunobiology 211: 75-84 (2006).
-
Aguillon JC, Cruzat A, Cuenca J, Cuchacovich M. Tumor necrosis factor alpha genetic polymorphism as a risk factor in disease.
Rev. Med. Chil. 130: 1043-1050 (2002).
-
Aharoni R, Kayhan B, Brenner O, Domev H, Labunskay G, Arnon R. Immunomodulatory therapeutic effect of glatiramer acetate on several murine models of inflammatory bowel disease.
J. Pharmacol. Exp. Ther. 318: 68-78 (2006).
*
-
Aherrahrou Z, Axtner SB, Kaczmarek PM, Jurat A, Korff S, Doehring LC, Weichenhan D, Katus HA, Ivandic BT. A locus on chromosome 7 determines dramatic up-regulation of osteopontin in dystrophic cardiac calcification in mice.
Am. J. Pathol. 164: 1379-1387 (2004).
*
-
Ahluwalia A, Clodfelter KH, Waxman DJ. Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis.
Mol. Endocrinol. 18: 747-760 (2004).
*
-
Ahluwalia J, Tinker A, Clapp LH, Duchen MR, Abramov AY, Pope S, Nobles M, Segal AW. The large-conductance Ca2+-activated K+ channel is essential for innate immunity.
Nature 427: 853-858 (2004).
*
-
Ahluwalia TS, Ahuja M, Rai TS, Kohli HS, Sud K, Bhansali A, Khullar M. Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians.
Mol. Cell. Biochem. 314: 9-17 (2008).
*
-
Ahmad R, Qureshi HY, El Mabrouk M, Sylvester J, Ahmad M Dr, Zafarullah M. Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma.
Ann. Rheum. Dis. 66: 782-789 (2007).
*
-
Ahmad R, Sylvester J, Zafarullah M. MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation.
Cell. Signal. 19: 2549-2557 (2007).
*
-
Ahmad T, Marshall SE, Mulcahy-Hawes K, Orchard T, Crawshaw J, Armuzzi A, Neville M, van Heel D, Barnardo M, Welsh KI, Jewell DP, Bunce M. High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility.
Tissue Antigens 60: 164-179 (2002).
*
-
Ahmad W, Panteleyev AA, Christiano AM. The molecular basis of congenital atrichia in humans and mice: mutations in the hairless gene.
J. Investig. Dermatol. Symp. Proc. 4: 240-243 (1999).
*
-
Ahmad YA, Bruce IN. Genetic epidemiology: systemic lupus erythematosus.
Arthritis Res. 3: 331-336 (2001).
*
-
Ahmadi KR, Lanchbury JS, Reed P, Chiano M, Thompson D, Galley M, Line A, Lank E, Wong HJ, Strachan D, Spector TD. Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels.
Genes Immun. 4: 289-297 (2003).
*
-
Ahmed FE, Jeffries CD, Vos PW, Flake G, Nuovo GJ, Sinar DR, Naziri W, Marcuard SP. Diagnostic microRNA markers for screening sporadic human colon cancer and active ulcerative colitis in stool and tissue.
Cancer Genomics Proteomics 6: 281-295 (2009).
-
Ahmed MA, Jackson D, Seth R, Robins A, Lobo DN, Tomlinson IP, Ilyas M. CD24 is upregulated in inflammatory bowel disease and stimulates cell motility and colony formation.
Inflamm. Bowel Dis. Dec 8 [Epub ahead of print] (2009).
*
-
Ahmed MB, Belhadj Hmida N, Moes N, Buyse S, Abdeladhim M, Louzir H, Cerf-Bensussan N. IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway.
J. Immunol. 182: 6763-6770 (2009).
-
Ahmed RA, Murao K, Imachi H, Yu X, Li J, Wong NC, Ishida T. Human scavenger receptor class B type 1 is regulated by activators of peroxisome proliferators-activated receptor-gamma in hepatocytes.
Endocrine 35: 233-242 (2009).
-
Ahmed SS, Tan FK. Identification of novel targets in scleroderma: update on population studies, cDNA arrays, SNP analysis, and mutations.
Curr. Opin. Rheumatol. 15: 766-771 (2003).
-
Ahmed TA, Buzzelli MD, Lang CH, Capen JB, Shumate ML, Navaratnarajah M, Nagarajan M, Cooney RN. Interleukin-6 inhibits growth hormone-mediated gene expression in hepatocytes.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1793-G1803 (2007).
*
-
Ahmed W, Orasanu G, Nehra V, Asatryan L, Rader DJ, Ziouzenkova O, Plutzky J. High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha. A candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion.
Circ. Res. 98: 490-498 (2006).
*
-
Ahn D, Crawley S, Hokari R, Kato S, Yang S, Li J, Kim Y. TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation.
Cell. Physiol. Biochem. 15: 29-40 (2005).
*
-
Ahn J, Gammon MD, Santella RM, Gaudet MM, Britton JA, Teitelbaum SL, Terry MB, Neugut AI, Eng SM, Zhang Y, Garza C, Ambrosone CB. Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk.
Carcinogenesis 27: 1876-1882 (2006).
*
-
Ahn S, Lee G, Yang SJ, Lee D, Lee S, Shin HS, Kim MC, Lee KN, Palmer DC, Theoret MR, Jenkinson EJ, Anderson G, Restifo NP, Kim MG. TSCOT (+) thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation.
PLoS Biol. 6: e191 (2008).
*
-
Ahn SH, Shah YM, Inoue J, Morimura K, Kim I, Yim S, Lambert G, Kurotani R, Nagashima K, Gonzalez FJ, Inoue Y. Hepatocyte nuclear factor 4 in the intestinal epithelial cells protects against inflammatory bowel disease.
Inflamm. Bowel Dis. 14: 908-920 (2008).
*
-
Aho AD, McNulty AM, Coussens PM. Enhanced expression of interleukin-1alpha and tumor necrosis factor receptor-associated protein 1 in ileal tissues of cattle infected with Mycobacterium avium subsp. paratuberculosis.
Infect. Immun. 71: 6479-6486 (2003).
*
-
Aho TL, Sandholm J, Peltola KJ, Ito Y, Koskinen PJ. Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity.
BMC Cell Biol. 7: 21 (2006).
*
-
Ahrendt M, Hammerschmidt SI, Pabst O, Pabst R, Bode U. Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses.
J. Immunol. 181: 1898-1907 (2008).
*
-
Ahrendt SA, Rashid A, Chow JT, Eisenberger CF, Pitt HA, Sidransky D. p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.
J. Hepatobiliary Pancreat. Surg. 7: 426-431 (2000).
-
Ahrens R, Waddell A, Seidu L, Blanchard C, Carey R, Forbes E, Lampinen M, Wilson T, Cohen E, Stringer K, Ballard E, Munitz A, Xu H, Lee N, Lee JJ, Rothenberg ME, Denson L, Hogan SP. Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis.
J. Immunol. 181: 7390-7399 (2008).
*
-
Ahuja HS, Szanto A, Nagy L, Davies PJ. The retinoid X receptor and its ligands: versatile regulators of metabolic function, cell differentiation and cell death.
J. Biol. Regul. Homeost. Agents 17: 29-45 (2003).
-
Ahuja J, Kampani K, Datta S, Wigdahl B, Flaig KE, Jain P. Use of human antigen presenting cell gene array profiling to examine the effect of human T-cell leukemia virus type 1 Tax on primary human dendritic cells.
J. Neurovirol. 12: 47-59 (2006).
-
Ahuja V, Dieckgraefe B, Anant S. Molecular biology of the small intestine.
Curr. Opin. Gastroenterol. 22: 90-94 (2006).
-
Ahyi AN, Chang HC, Dent AL, Nutt SL, Kaplan MH. IFN regulatory factor 4 regulates the expression of a subset of Th2 cytokines.
J. Immunol. 183: 1598-1606 (2009).
-
Ai ZL, Chen DF. The significance and effects of liver X receptor alpha in nonalcoholic fatty liver disease in rats.
Zhonghua Gan Zang Bing Za Zhi 15: 127-130 (2007).
-
Aiba A, Nakajima A, Okawa A, Koda M, Yamazaki M. Evidence of enhanced expression of osteopontin in spinal hyperostosis of the twy mouse.
Spine (Phila Pa 1976) 34: 1644-1649 (2009).
-
Aida K, Tawata M, Negishi M, Onaya T. Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone.
Horm. Metab. Res. 29: 646-649 (1997).
-
Aigner E, Theurl I, Theurl M, Lederer D, Haufe H, Dietze O, Strasser M, Datz C, Weiss G. Pathways underlying iron accumulation in human nonalcoholic fatty liver disease.
Am. J. Clin. Nutr. 87: 1374-1383 (2008).
*
-
Aihara K, Azuma H, Matsumoto T. Vitamin D-vitamin D receptor system regulates antithrombogenicity in vivo.
Clin. Calcium 16: 1173-1179 (2006).
-
Ainola M, Mandelin J, Liljestrom M, Konttinen YT, Salo J. Imbalanced expression of RANKL and osteoprotegerin mRNA in pannus tissue of rheumatoid arthritis.
Clin. Exp. Rheumatol. 26: 240-246 (2008).
-
Ainsworth DM, Wagner B, Franchini M, Grunig G, Erb HN, Tan JY. Time-dependent alterations in gene expression of interleukin-8 in the bronchial epithelium of horses with recurrent airway obstruction.
Am. J. Vet. Res. 67: 669-677 (2006).
-
Aird RE, Thomson M, Macpherson JS, Thurston DE, Jodrell DI, Guichard SM. ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
Pharmacogenomics J. 8: 289-296 (2008).
-
Aitken AE, Morgan E. Gene-specific effects of inflammatory cytokines on cytochrome P4502C, 2B6 and 3A4 mRNA levels in human hepatocytes.
Drug Metab. Dispos. 35: 1687-1693 (2007).
*
-
Aittoniemi J, Soranummi H, Rovio AT, Hurme M, Pessi T, Nieminen M, Karjalainen J. Mannose-binding lectin 2 (MBL2) gene polymorphism in asthma and atopy among adults.
Clin. Exp. Immunol. 142: 120-124 (2005).
*
-
Aizu T, Tamai K, Nakano H, Rokunohe D, Toyomaki Y, Uitto J, Sawamura D. Calcineurin/NFAT-dependent regulation of 230-kDa bullous pemphigoid antigen (BPAG1) gene expression in normal human epidermal keratinocytes.
J. Dermatol. Sci. 51: 45-51 (2008).
-
Ajima R, Akiyama T, Usui M, Yoneda M, Yoshida Y, Nakamura T, Minowa O, Noda M, Tanaka S, Noda T, Yamamoto T. Osteoporotic bone formation in mice lacking Tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation.
FEBS Lett. 582: 1313-1318 (2008).
*
-
Ajjan RA, Weetman AP. New understanding of the role of cytokines in the pathogenesis of Graves' ophthalmopathy.
J. Endocrinol. Invest. 27: 237-245 (2004).
-
Ajonuma LC, Chan PK, Ng EH, Fok KL, Wong CH, Tsang LL, Tang XX, Ho LS, Lau MC, Chung CM, He Q, Huang HY, Yang DZ, Rowlands DK, Chung YW, Chan HC. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection.
J. Obstet. Gynaecol. Res. 34: 923-930 (2008).
-
Ajonuma LC, Tsang LL, Zhang GH, Wong CH, Lau MC, Ho LS, Rowlands DK, Zhou CX, Ng CP, Chen J, Xu PH, Zhu JX, Chung YW, Chan HC. Estrogen-induced abnormally high CFTR expression results in ovarian hyperstimulation syndrome.
Mol. Endocrinol. 19: 3038-3044 (2005).
*
-
Akaishi H, Takeda K, Kaisho T, Shineha R, Satomi S, Takeda J, Akira S. Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes.
Int. Immunol. 10: 1747-1751 (1998).
*
-
Akaogi J, Nozaki T, Satoh M, Yamada H. Role of PGE2 and EP receptors in the pathogenesis of rheumatoid arthritis and as a novel therapeutic strategy.
Endocr. Metab. Immune Disord. Drug Targets 6: 383-394 (2006).
-
Akar CA, Feinstein DL. Modulation of inducible nitric oxide synthase expression by sumoylation.
J. Neuroinflammation 6: 12 (2009).
-
Akazawa A, Sakaida I, Higaki S, Kubo Y, Uchida K, Okita K. Increased expression of tumor necrosis factor-alpha messenger RNA in the intestinal mucosa of inflammatory bowel disease, particularly in patients with disease in the inactive phase.
J. Gastroenterol. 37: 345-353 (2002).
*
-
Akbiyik F, Cinar K, Demirpence E, Ozsullu T, Tunca R, Haziroglu R, Yurdaydin C, Uzunalimoglu O, Bozkaya H. Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver.
Eur. J. Clin. Invest. 34: 429-435 (2004).
-
Akech J, Wixted JJ, Bedard K, van der Deen M, Hussain S, Guise TA, van Wijnen AJ, Stein JL, Languino LR, Altieri DC, Pratap J, Keller E, Stein GS, Lian JB. Runx2 association with progression of prostate cancer in patients: mechanisms mediating bone osteolysis and osteoblastic metastatic lesions.
Oncogene Nov 16 [Epub ahead of print] (2009).
*
-
Akesson LS, Duffy DL, Phelps SC, Thompson PJ, Kedda MA. A polymorphism in the promoter region of the human interleukin-16 gene is not associated with asthma or atopy in an Australian population.
Clin. Exp. Allergy 35: 327-331 (2005).
*
-
Akgul S, Erbil Y, Giris M, Alis H, Yanik BT, Olgac V, Toker GA. The effect of octreotide on pancreatic damage in TNBS-induced colitis.
Surg. Innov. 13: 102-108 (2006).
-
Akhmetshina A, Dees C, Busch N, Beer J, Sarter K, Zwerina J, Zimmer A, Distler O, Schett G, Distler JH. The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis.
Arthritis Rheum. 60: 1129-1136 (2009).
*
-
Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee YH, Ricote M, Glass CK, Brewer HB Jr, Gonzalez FJ. Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux.
Mol. Cell. Biol. 22: 2607-2619 (2002).
*
-
Akiyama TE, Ward JM, Gonzalez FJ. Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha). Alterations in fatty acid homeostasis in HNF1alpha-deficient mice.
J. Biol. Chem. 275: 27117-27122 (2000).
*
-
Akiyoshi H, Hatakeyama S, Pitkanen J, Mouri Y, Doucas V, Kudoh J, Tsurugaya K, Uchida D, Matsushima A, Oshikawa K, Nakayama KI, Shimizu N, Peterson P, Matsumoto M. Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner.
J. Biol. Chem. 279: 33984-33991 (2004).
*
-
Akkad DA, Arning L, Ibrahim SM, Epplen JT. Sex specifically associated promoter polymorphism in multiple sclerosis affects interleukin 4 expression levels.
Genes Immun. 8: 703-706 (2007).
*
-
Akkad DA, Kruse N, Arning L, Gold R, Epplen JT. Genomic NGFB variation and multiple sclerosis in a case control study.
BMC Med. Genet. 9: 107 (2008).
*
-
Akkiprik M, Celikel CA, Dusunceli F, Sonmez O, Gulluoglu BM, Sav A, Ozer A. Relationship between overexpression of ras p21 oncoprotein and K-ras codon 12 and 13 mutations in Turkish colorectal cancer patients.
Turk. J. Gastroenterol. 19: 22-27 (2008).
*
-
Akkiz H, Bayram S, Bekar A, Akgollu E, Ozdil B. Relationship between functional polymorphism in the Aurora A gene and susceptibility of hepatocellular carcinoma.
J. Viral Hepat. Dec 14 [Epub ahead of print] (2009).
-
Akkiz H, Bayram S, Bekar A, Ozdil B, Akgollu E, Sumbul AT, Demiryurek H, Doran F. G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: Case-control study.
Cancer Epidemiol. 33: 261-264 (2009).
-
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, Stein L, Russo R, Goldsmith D, Dent P, Rosenberg HF, Austin F, Remmers EF, Balow JE Jr, Rosenzweig S, Komarow H, Shoham NG, Wood G, Jones J, Mangra N, Carrero H, Adams BS, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases.
Arthritis Rheum. 46: 3340-3348 (2002).
*
-
Aksoy E, Albarani V, Nguyen M, Laes JF, Ruelle JL, De Wit D, Willems F, Goldman M, Goriely S. Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells.
Blood 109: 2887-2893 (2007).
*
-
Aktas E, Ciftci F, Bilgic S, Sezer O, Bozkanat E, Deniz O, Citici U, Deniz G. Peripheral immune response in pulmonary tuberculosis.
Scand. J. Immunol. 70: 300-308 (2009).
*
-
Akyildiz M, Gunsar F, Nart D, Sahin O, Yilmaz F, Akay S, Ersoz G, Karasu Z, Ilter T, Batur Y, Berdeli A, Akarca U. Macrophage migration inhibitory factor expression and MIF gene -173 G/C polymorphism in nonalcoholic fatty liver disease.
Eur. J. Gastroenterol. Hepatol. Oct 13 [Epub ahead of print] (2009).
-
Al-Alem U, Li C, Forey N, Relouzat F, Fondaneche MC, Tavtigian SV, Wang ZQ, Latour S, Yin L. Impaired Ig class switch in mice deficient for the X-linked lymphoproliferative disease gene Sap.
Blood 106: 2069-2075 (2005).
*
-
Al-Dosari MS, Knapp JE, Liu D. Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver.
Mol. Pharm. 3: 322-328 (2006).
*
-
Al-Falahi Y, Sand KL, Knudsen E, Damaj BB, Rolin J, Maghazachi AA. Splenic natural killer cell activity in two models of experimental neurodegenerative diseases.
J. Cell. Mol. Med. Dec 29 [Epub ahead of print] (2008).
*
-
Al-Hasani H, Joost HG. Nutrition-/diet-induced changes in gene expression in white adipose tissue.
Best Pract. Res. Clin. Endocrinol. Metab. 19: 589-603 (2005).
-
Al-Izki S, Pryce G, Giovannoni G, Baker D. Evaluating potential therapies for bladder dysfunction in a mouse model of multiple sclerosis with high-resolution ultrasonography.
Mult. Scler. 15: 795-801 (2009).
*
-
Al-Kandari W, Jambunathan S, Navalgund V, Koneni R, Freer M, Parimi N, Mudhasani R, Fontes JD. ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription.
Mol. Immunol. 44: 311-321 (2007).
*
-
Al-Kandari W, Koneni R, Navalgund V, Aleksandrova A, Jambunathan S, Fontes JD. The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription.
J. Mol. Biol. 369: 1175-1187 (2007).
*
-
Al-Khalidi JA, Czaja AJ. Current concepts in the diagnosis, pathogenesis, and treatment of autoimmune hepatitis.
Mayo Clin. Proc. 76: 1237-1252 (2001).
*
-
Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A. Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle.
Mol. Endocrinol. 20: 3364-3375 (2006).
*
-
Al-Muhsen S, Casanova JL. The genetic heterogeneity of Mendelian susceptibility to mycobacterial diseases.
J. Allergy Clin. Immunol. 122: 1043-1051 (2008).
*
-
Al-Refu K, Goodfield M. Hair follicle stem cells in the pathogenesis of the scarring process in cutaneous lupus erythematosus.
Autoimmun. Rev. 8: 474-477 (2009).
-
Al-Saleh J, el-Eissawy S. The role of T helper cell subsets in pathogenesis of systemic lupus erythematosus and their relation to disease activity.
Egypt. J. Immunol. 13: 41-48 (2006).
-
Al-Toma A, Goerres MS, Meijer JW, von Blomberg BM, Wahab PJ, Kerckhaert JA, Mulder CJ. Cladribine therapy in refractory celiac disease with aberrant T cells.
Clin. Gastroenterol. Hepatol. 4: 1322-1327 (2006).
-
Ala A, Schilsky ML. Inherited metabolic liver disease.
Curr. Opin. Gastroenterol. 20: 198-207 (2004).
-
Alaez C, Gazit E, Ibarrola B, Yaron M, Livneh A, Avishai O, Gorodezky C. Distribution of HLA-B27 subtypes in ankylosing spondylitis in an Israeli population.
Arch. Med. Res. 38: 452-455 (2007).
-
Alaez C, Vazquez-Garcia MN, Gorodezky C. DQA1 and DQB1 promoter diversity and linkage disequilibrium with class II haplotypes in Mexican Mestizo population.
Genes Immun. 2: 216-221 (2001).
*
-
Alagarasu K, Selvaraj P, Swaminathan S, Raghavan S, Narendran G, Narayanan PR. Mannose binding lectin gene variants and susceptibility to tuberculosis in HIV-1 infected patients of South India.
Tuberculosis (Edinb.) 87: 535-543 (2007).
-
Alaminos M, Gonzalez-Andrades M, Munoz-Avila JI, Garzon I, Sanchez-Quevedo MC, Campos A. Volumetric and ionic regulation during the in vitro development of a corneal endothelial barrier.
Exp. Eye Res. 86: 758-769 (2008).
-
Alarcon-Aguilar FJ, Almanza-Perez J, Blancas G, Angeles S, Garcia-Macedo R, Roman R, Cruz M. Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice.
Eur. J. Pharmacol. 599: 152-158 (2008).
*
-
Alarcon-Riquelme ME. Recent advances in the genetics of autoimmune diseases.
Ann. N. Y. Acad. Sci. 1110: 1-9 (2007).
*
-
Alavi K, Schwartz MZ, Palazzo JP, Prasad R. Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2.
J. Pediatr. Surg. 35: 847-851 (2000).
-
Alaynick WA. Nuclear receptors, mitochondria and lipid metabolism.
Mitochondrion 8: 329-337 (2008).
-
Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha.
J. Immunol. 162: 494-502 (1999).
*
-
Albanesi C, De Pita O, Girolomoni G. Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes.
Clin. Dermatol. 25: 581-688 (2007).
-
Albanesi C, Scarponi C, Cavani A, Federici M, Nasorri F, Girolomoni G. Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes.
J. Invest. Dermatol. 115: 81-87 (2000).
*
-
Albano E. Oxidative mechanisms in the pathogenesis of alcoholic liver disease.
Mol. Aspects Med. 29: 9-16 (2008).
-
Alberati-Giani D, Malherbe P, Ricciardi-Castagnoli P, Kohler C, Denis-Donini S, Cesura AM. Differential regulation of indoleamine 2,3-dioxygenase expression by nitric oxide and inflammatory mediators in IFN-gamma-activated murine macrophages and microglial cells.
J. Immunol. 159: 419-426 (1997).
-
Albert CJ, Anbukumar DS, Monda JK, Eckelkamp JT, Ford DA. Myocardial lipidomics. Developments in myocardial nuclear lipidomics.
Front. Biosci. 12: 2750-2760 (2007).
-
Albert PJ, Proal AD, Marshall TG. Vitamin D: the alternative hypothesis.
Autoimmun. Rev. 8: 639-644 (2009).
*
-
Alberti S, Schuster G, Parini P, Feltkamp D, Diczfalusy U, Rudling M, Angelin B, Bjorkhem I, Pettersson S, Gustafsson JA. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice.
J. Clin. Invest. 107: 565-573 (2001).
*
-
Albertsmeyer AC, Kakkassery V, Spurr-Michaud S, Beeks O, Gipson IK. Effect of pro-inflammatory mediators on membrane-associated mucins expressed by human ocular surface epithelial cells.
Exp. Eye Res. Dec 23 [Epub ahead of print] (2009).
*
-
Alblowi J, Kayal RA, Siqueria M, McKenzie E, Krothapalli N, McLean J, Conn J, Nikolajczyk B, Einhorn TA, Gerstenfeld L, Graves DT. High levels of tumor necrosis factor-alpha contribute to accelerated loss of cartilage in diabetic fracture healing.
Am. J. Pathol. 175: 1574-1585 (2009).
*
-
Albrecht U, Yang X, Asselta R, Keitel V, Tenchini ML, Ludwig S, Heinrich PC, Haussinger D, Schaper F, Bode JG. Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene.
Cell. Signal. 19: 1866-1878 (2007).
*
-
Albrecht V, Hofer TP, Foxwell B, Frankenberger M, Ziegler-Heitbrock L. Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1.
BMC Immunol. 9: 69 (2008).
*
-
Alcaraz A, Hernandez D, Iyu D, Mota R, Ortiz AJ, Atucha NM, Garcia-Estan J, Ortiz MC. Effects of chronic L-NAME on nitrotyrosine expression and renal vascular reactivity in rats with chronic bile duct ligation.
Clin. Sci. (Lond.) 115: 57-68 (2008).
*
-
Alcorta DA, Barnes DA, Dooley MA, Sullivan P, Jonas B, Liu Y, Lionaki S, Reddy CB, Chin H, Dempsey AA, Jennette JC, Falk RJ. Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis.
Kidney Int. 72: 853-864 (2007).
*
-
Alcudia JF, Martinez-Gonzalez J, Guadall A, Gonzalez-Diez M, Badimon L, Rodriguez C. Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines.
Front. Biosci. 13: 2721-2727 (2008).
-
Alderuccio F, Toh BH. Induction of tolerance to self-antigens using genetically modified bone marrow cells.
Expert Opin. Biol. Ther. 4: 1007-1014 (2004).
-
Aldhous MC, Noble CL, Satsangi J. Dysregulation of human beta-defensin-2 protein in inflammatory bowel disease.
PLoS One 4: e6285 (2009).
*
-
Aldinger KA, Lehmann OJ, Hudgins L, Chizhikov VV, Bassuk AG, Ades LC, Krantz ID, Dobyns WB, Millen KJ. FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation.
Nat. Genet. 41: 1037-1042 (2009).
*
-
Aldred PM, Hollox EJ, Armour JA. Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3.
Hum. Mol. Genet. 14: 2045-2052 (2005).
*
-
Ale-Agha N, Galban S, Sobieroy C, Abdelmohsen K, Gorospe M, Sies H, Klotz LO. HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity.
Hepatology 50: 1567-1576 (2009).
-
Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, Vizzutti F, Anania FA, Milani S, Rombouts K, Laffi G, Pinzani M, Marra F. Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells.
Hepatology 42: 1339-1348 (2005).
*
-
Alegre ML, Fallarino F. Mechanisms of CTLA-4-Ig in tolerance induction.
Curr. Pharm. Des. 12: 149-160 (2006).
-
Aleksic T, Baumann B, Wagner M, Adler G, Wirth T, Weber CK. Cellular immune reaction in the pancreas is induced by constitutively active IKK2.
Gut 56: 227-236 (2007).
*
-
Aleksunes LM, Manautou JE. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease.
Toxicol. Pathol. 35: 459-473 (2007).
*
-
Aleksunes LM, Slitt AL, Maher JM, Dieter MZ, Knight TR, Goedken M, Cherrington NJ, Chan JY, Klaassen CD, Manautou JE. Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis.
Cell Stress Chaperones 11: 356-363 (2006).
-
Aleman G, Torres N, Tovar AR. Peroxisome proliferator-activated receptors (PPARs) in obesity and insulin resistance development.
Rev. Invest. Clin. 56: 351-367 (2004).
-
Alemany Bonastre R, Barquinero Manez J, Ramon y Cajal Agueras S. Gene therapy: current situation and expectations.
Rev. Clin. Esp. 205: 178-188 (2005).
-
Alenghat T, Meyers K, Mullican SE, Leitner K, Adeniji-Adele A, Avila J, Bucan M, Ahima RS, Kaestner KH, Lazar MA. Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology.
Nature 456: 997-1000 (2008).
*
-
Alenghat T, Yu J, Lazar MA. The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor.
EMBO J. 25: 3966-3974 (2006).
*
-
Alenius GM. Psoriatic arthritis - new insights give new options for treatment.
Curr. Med. Chem. 14: 359-366 (2007).
-
Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G. Peroxisome proliferator-activated receptor (PPAR)-gamma positively controls and PPARalpha negatively controls cyclooxygenase-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels.
Mol. Pharmacol. 76: 414-424 (2009).
*
-
Alex P, Gucek M, Li X. Applications of proteomics in the study of inflammatory bowel diseases: current status and future directions with available technologies.
Inflamm. Bowel Dis. 15: 616-629 (2009).
*
-
Alexa K, Choe SK, Hirsch N, Etheridge L, Laver E, Sagerstrom CG. Maternal and zygotic aldh1a2 activity is required for pancreas development in zebrafish.
PLoS One 4: e8261 (2009).
*
-
Alexaki VI, Notas G, Pelekanou V, Kampa M, Valkanou M, Theodoropoulos P, Stathopoulos EN, Tsapis A, Castanas E. Adipocytes as immune cells: differential expression of TWEAK, BAFF, and APRIL and their receptors (Fn14, BAFF-R, TACI, and BCMA) at different stages of normal and pathological adipose tissue development.
J. Immunol. 183: 5948-5956 (2009).
-
Alexander BT. Epigenetic changes in gene expression. Focus on "the liver X-teceptor (LXR) gene promoter is hypermethylated in a mouse model of prenatal protein restriction"
Am. J. Physiol. Regul. Integr. Comp. Physiol. Dec 2 [Epub ahead of print] (2009).
*
-
Alexander D, Friedrich B, Abruzzese T, Gondolph-Zink B, Wulker N, Aicher WK. The active form of leflunomide, HMR1726, facilitates TNF-alpha and IL-17 induced MMP-1 and MMP-3 expression.
Cell. Physiol. Biochem. 17: 69-78 (2006).
*
-
Alexander JS, Ando T. Density-dependent control of MAdCAM-1 and chronic inflammation. Focus on "Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells".
Am. J. Physiol. Cell Physiol. 288: C243-C244 (2005).
*
-
Alexander K, Edwards C, Misko IS, Geczy AF, Bashir HV, Edmonds JP. The distribution of a specific HLA-B27-associated cell surface component on the tissues of patients with ankylosing spondylitis.
Clin. Exp. Immunol. 45: 158-164 (1981).
*
-
Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF. Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease.
Dig. Dis. Sci. 41: 660-669 (1996).
-
Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF. Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease.
Dig. Dis. Sci. 40: 485-494 (1995).
-
Alexander RT, Woudenberg-Vrenken TE, Buurman J, Dijkman H, van der Eerden BC, van Leeuwen JP, Bindels RJ, Hoenderop JG. Klotho prevents renal calcium loss.
J. Am. Soc. Nephrol. 20: 2371-2379 (2009).
-
Alexander S, Bramson J, Foley R, Xing Z. Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein.
Blood 103: 93-99 (2004).
*
-
Alexander WS, Hilton DJ. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response.
Annu. Rev. Immunol. 22: 503-529 (2004).
*
-
Alexiou P, Vergoulis T, Gleditzsch M, Prekas G, Dalamagas T, Megraw M, Grosse I, Sellis T, Hatzigeorgiou AG. miRGen 2.0: a database of microRNA genomic information and regulation.
Nucleic Acids Res. 38: D137-D141 (2010).
*
-
Alexis AF, Dudda-Subramanya R, Siu K, Sinha AA. Alopecia areata: genetic complexity underlies clinical heterogeneity.
Eur. J. Dermatol. 17: 367-374 (2007).
*
-
Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, Peden DB. Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals.
Ann. Allergy Asthma Immunol. 100: 206-215 (2008).
-
Alexopoulou L, Kontoyiannis D. Intestinal epithelial barrier and mucosal immunity. Contribution of microbial-associated molecules in innate mucosal responses.
Cell. Mol. Life Sci. 62: 1349-1358 (2005).
*
-
Alfalah M, Keiser M, Leeb T, Zimmer KP, Naim HY. Compound heterozygous mutations affect protein folding and function in patients with congenital sucrase-isomaltase deficiency.
Gastroenterology 136: 883-892 (2009).
*
-
Alfter K, von Kugelgen I, Haenisch B, Frieling T, Hulsdonk A, Haars U, Rolfs A, Noe G, Kolck UW, Homann J, Molderings GJ. New aspects of liver abnormalities as part of the systemic mast cell activation syndrome.
Liver Int. 29: 181-186 (2009).
*
-
Algood HM, Flynn JL. CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration.
J. Immunol. 173: 3287-3296 (2004).
*
-
Ali BR. Is cystic fibrosis-related diabetes an apoptotic consequence of ER stress in pancreatic cells?
Med. Hypotheses 72: 55-57 (2009).
-
Ali F, Ali NS, Bauer A, Boyle JJ, Hamdulay SS, Haskard DO, Randi AM, Mason JC. PPARdelta and PGC1alpha act cooperatively to induce heme oxygenase-1 and enhance vascular endothelial cell resistance to stress.
Cardiovasc. Res. Nov 10 [Epub ahead of print] (2009).
-
Ali MS, Pearson JP. Upper airway mucin gene expression: a review.
Laryngoscope 117: 932-938 (2007).
-
Alic M. Is exposure to a patient with Crohn's disease an environmental factor for developing the disease.
Gut 45: 631-632 (1999).
*
-
Alimohammadi M, Bjorklund P, Hallgren A, Pontynen N, Szinnai G, Shikama N, Keller MP, Ekwall O, Kinkel SA, Husebye ES, Gustafsson J, Rorsman F, Peltonen L, Betterle C, Perheentupa J, Akerstrom G, Westin G, Scott HS, Hollander GA, Kampe O. Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen.
N. Engl. J. Med. 358: 1018-1028 (2008).
*
-
Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH. Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13.
Proc. Natl. Acad. Sci. U.S.A. 104: 2827-2830 (2007).
*
-
Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb AL, Frausto RF, Bhan V, Kiosses WB, Whitton JL, Robertson GS, Crocker SJ. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis.
Autophagy 5: 152-158 (2009).
-
Alkhoury F, Malo MS, Mozumder M, Mostafa G, Hodin RA. Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2.
Am. J. Physiol. Gastrointest. Liver Physiol. 289: G285-G290 (2005).
*
-
Alkim C, Balci M, Alkim H, Dagli U, Parlak E, Tezel A, Ulker A. The importance of peripheral immune cells in inflammatory bowel disease.
Turk. J. Gastroenterol. 18: 82-88 (2007).
*
-
Alkim C, Savas B, Ensari A, Alkim H, Dagli U, Parlak E, Ulker A, Sahin B. Expression of p53, VEGF, microvessel density, and cyclin-D1 in noncancerous tissue of inflammatory bowel disease.
Dig. Dis. Sci. 54: 1979-1984 (2009).
*
-
Allam R, Lichtnekert J, Moll AG, Taubitz A, Vielhauer V, Anders HJ. Viral RNA and DNA trigger common antiviral responses in mesangial cells.
J. Am. Soc. Nephrol. 20: 1986-1996 (2009).
-
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs.
J. Clin. Invest. 115: 3276-3284 (2005).
*
-
Allay JA, Dennis JE, Haynesworth SE, Majumdar MK, Clapp DW, Shultz LD, Caplan AI, Gerson SL. LacZ and interleukin-3 expression in vivo after retroviral transduction of marrow-derived human osteogenic mesenchymal progenitors.
Hum. Gene Ther. 8: 1417-1427 (1997).
-
Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction.
Am. J. Clin. Nutr. 88: 934-940 (2008).
*
-
Allcock R, Dolecki KJ, Boodhoo A, Abdul Khalil A, Wong AM, Price P. Genomic sequence and expression profile of murine Bat1a and Nfkbil1.
DNA Seq. 17: 292-299 (2006).
-
Allcock RJ, Price P, Gaudieri S, Leelayuwat C, Witt CS, Dawkins RL. Characterisation of the human central MHC gene, BAT1: genomic structure and expression.
Exp. Clin. Immunogenet. 16: 98-106 (1999).
-
Allcock RJ, Williams JH, Price P. The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production.
Genes Cells 6: 487-494 (2001).
*
-
Allen CE, Richards J, Muthusamy N, Auer H, Liu Y, Robinson ML, Barnard JA, Wu LC. Disruption of ZAS3 in mice alters NF-kappaB and AP-1 DNA binding and T-cell development.
Gene Expr. 14: 83-100 (2007).
-
Allen K, Kim ND, Moon JO, Copple BL. Upregulation of early growth response factor-1 by bile acids requires mitogen-activated protein kinase signaling.
Toxicol. Appl. Pharmacol. 243: 63-67 (2010).
*
-
Aller MA, Arias JL, Garcia-Dominguez J, Arias JI, Duran M, Arias J. Experimental obstructive cholestasis: the wound-like inflammatory liver response.
Fibrogenesis Tissue Repair. 1: 6 (2008).
*
-
Aller MA, Arias JL, Prieto I, Losada M, Arias J. Bile duct ligation: step-by-step to cholangiocyte inflammatory tumorigenesis.
Eur. J. Gastroenterol. Hepatol. Jul 28 [Epub ahead of print] (2009).
-
Allgayer H. Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease.
Aliment. Pharmacol. Ther. 18 Suppl. 2: 10-14 (2003).
*
-
Allikmets R, Gerrard B, Hutchinson A, Dean M. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.
Hum. Mol. Genet. 5: 1649-1655 (1996).
*
-
Allison AC. Genetic control of resistance to human malaria.
Curr. Opin. Immunol. 21: 499-505 (2009).
-
Allison MC, Poulter LW. Changes in phenotypically distinct mucosal macrophage populations may be a prerequisite for the development of inflammatory bowel disease.
Clin. Exp. Immunol. 85: 504-509 (1991).
*
-
Almada L, Bellarosa C, Giraudi P, Mamprin M, Mediavilla M, Guibert E, Tiribelli C, Rodriguez J. The urea cycle enzymes activity and its gene expression in rat hepatocytes are not affected by cold storage in University of Wisconsin solution.
Ann. Hepatol. 4: 224-227 (2005).
-
Almaguel FG, Liu JW, Pacheco FJ, Casiano CA, De Leon M. Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid.
J. Neurosci. Res. 87: 1207-1218 (2009).
-
Almani M, Raffaeli S, Vider-Shalit T, Tsaban L, Fishbain V, Louzoun Y. Human self-protein CD8(+) T-cell epitopes are both positively and negatively selected.
Eur. J. Immunol. 39: 1056-1065 (2009).
*
-
Almeida M, Ambrogini E, Han L, Manolagas SC, Jilka RL. Increased lipid oxidation causes oxidative stress, increased PPARgamma expression and diminished pro-osteogenic Wnt signaling in the skeleton.
J. Biol. Chem. 284: 27438-27448 (2009).
*
-
Almeida PE, Silva AR, Maya-Monteiro CM, Torocsik D, Avila HD, Dezso B, Magalhaes KG, Castro-Faria-Neto HC, Nagy L, Bozza PT. Mycobacterium bovis Bacillus Calmette-Guerin infection induces TLR2-dependent peroxisome proliferator-activated receptor gamma expression and activation: functions in inflammation, lipid metabolism, and pathogenesis.
J. Immunol. 183: 1337-1345 (2009).
-
Almendro V, Fuster G, Busquets S, Ametller E, Figueras M, Argiles JM, Lopez-Soriano FJ. Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs.
Obesity (Silver Spring) 16: 285-289 (2008).
*
-
Almirza WH, Dernison MM, Peters PH, van Zoelen EJ, Theuvenet AP. Role of the prostanoid FP receptor in action potential generation and phenotypic transformation of NRK fibroblasts.
Cell. Signal. 20: 2022-2029 (2008).
*
-
Alonzo ES, Gottschalk RA, Das J, Egawa T, Hobbs RM, Pandolfi PP, Pereira P, Nichols KE, Koretzky GA, Jordan MS, Sant'angelo DB. Development of promyelocytic zinc finger and ThPOK-expressing innate gammadelta T cells is controlled by strength of TCR signaling and Id3 3.
J. Immunol. Dec 28 [Epub ahead of print] (2009).
-
Alotaibi H, Yaman E, Salvatore D, Di Dato V, Telkoparan P, Di Lauro R, Tazebay UH. Intronic elements in the Na+/I- symporter gene (NIS) interact with retinoic acid receptors and mediate initiation of transcription.
Nucleic Acids Res. Jan 31 [Epub ahead of print] (2010).
*
-
Alper CA, Marcus-Bagley D, Awdeh Z, Kruskall MS, Eisenbarth GS, Brink SJ, Katz AJ, Stein R, Bing DH, Yunis EJ, Schur PH. Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype.
Tissue Antigens 56: 207-216 (2000).
*
-
Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiocchi L, Holcomb LA, Caligiuri A, LeSage GD. Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion.
Gastroenterology 116: 179-186 (1999).
*
-
Alrefai WA, Tyagi S, Nazir TM, Barakat J, Anwar SS, Hadjiagapiou C, Bavishi D, Sahi J, Malik P, Goldstein J, Layden TJ, Ramaswamy K, Dudeja PK. Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization.
Biochim. Biophys. Acta 1511: 17-27 (2001).
*
-
Altes A, Bach V, Ruiz A, Esteve A, Felez J, Remacha AF, Sarda MP, Baiget M. Mutations in HAMP and HJV genes and their impact on expression of clinical hemochromatosis in a cohort of 100 Spanish patients homozygous for the C282Y mutation of HFE gene.
Ann. Hematol. 88: 951-955 (2009).
-
Altmayr F, Jusek G, Holzmann B. The neuropeptide CGRP causes repression of TNFalpha transcription and suppression of ATF-2 promoter recruitment in Toll-like receptor-stimulated dendritic cells.
J. Biol. Chem. Dec 14 [Epub ahead of print] (2009).
*
-
Altucci L, Rossin A, Hirsch O, Nebbioso A, Vitoux D, Wilhelm E, Guidez F, De Simone M, Schiavone EM, Grimwade D, Zelent A, de The H, Gronemeyer H. Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase a-mediated desubordination of retinoid X receptor.
Cancer Res. 65: 8754-8765 (2005).
*
-
Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells.
Mol. Endocrinol. 23: 444-453 (2009).
*
-
Aluru M, Xu Y, Guo R, Wang Z, Li S, White W, Wang K, Rodermel S. Generation of transgenic maize with enhanced provitamin A content.
J. Exp. Bot. 59: 3551-3562 (2008).
*
-
Alvarado J, Del Castillo JR, Thomas LE. Modulation of membrane type 1 matrix metalloproteinase by LPS and gamma interferon bound to extracellular matrix in intestinal crypt cells.
Cytokine 41: 155-161 (2008).
-
Alvarado J, Taylor P, Castillo JR, Thomas LE. Interferon gamma bound to extracellular matrix changes the hyporesponsiveness to LPS in crypt but not villous intestinal epithelial cells.
Immunol. Lett. 99: 109-112 (2005).
-
Alvarado-Navarro A, Montoya-Buelna M, Munoz-Valle JF, Lopez-Roa RI, Guillen-Vargas C, Fafutis-Morris M. The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico.
Immunol. Lett. 118: 148-151 (2008).
-
Alvarez BV, Kieller DM, Quon AL, Markovich D, Casey JR. Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart.
J. Physiol. 561: 721-734 (2004).
*
-
Alvarez D, Arkinson JL, Sun J, Fattouh R, Walker T, Jordana M. Th2 differentiation in distinct lymph nodes influences the site of mucosal Th2 immune-inflammatory responses.
J. Immunol. 179: 3287-3296 (2007).
*
-
Alvarez E, Moga E, Barquinero J, Sierra J, Briones J. Dendritic and tumor cell fusions transduced with adenovirus encoding CD40L eradicate B-cell lymphoma and induce a Th17-type response.
Gene Ther. Dec 14 [Epub ahead of print] (2009).
-
Alvarez I, Lopez de Castro JA. HLA-B27 and immunogenetics of spondyloarthropathies.
Curr. Opin. Rheumatol. 12: 248-253 (2000).
-
Alvarez JI. Inhibition of Toll-like receptor immune responses by microbial pathogens.
Front. Biosci. 10: 582-587 (2005).
-
Alvarez L, Jara P, Sanchez-Sabate E, Hierro L, Larrauri J, Diaz MC, Camarena C, De La Vega A, Frauca E, Lopez-Collazo E, Lapunzina P. Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1.
Hum. Mol. Genet. 13: 2451-2460 (2004).
*
-
Alvarez R, Checa M, Brun S, Vinas O, Mampel T, Iglesias R, Giralt M, Villarroya F. Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids.
Biochem. J. 345: 91-97 (2000).
*
-
Alvarez R, de Andres J, Yubero P, Vinas O, Mampel T, Iglesias R, Giralt M, Villarroya F. A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene.
J. Biol. Chem. 270: 5666-5673 (1995).
*
-
Alvarez S, Khanwalkar H, Alvarez R, Erb C, Martinez C, Rodriguez-Barrios F, Germain P, Gronemeyer H, de Lera AR. C3 halogen and C8'' substituents on stilbene arotinoids modulate retinoic acid receptor subtype function.
ChemMedChem. 4: 1630-1640 (2009).
*
-
Alvarez Y, Tang X, Coligan JE, Borrego F. The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling.
Mol. Immunol. 45: 253-258 (2008).
*
-
Alvarez-Díaz S, Valle N, Garcia JM, Pena C, Freije JM, Quesada V, Astudillo A, Bonilla F, Lopez-Otin C, Munoz A. Cystatin D is a candidate tumor suppressor gene induced by vitamin D in human colon cancer cells.
J. Clin. Invest. 119: 2343-2358 (2009).
*
-
Alvarez-Pellitero P. Fish immunity and parasite infections: from innate immunity to immunoprophylactic prospects.
Vet. Immunol. Immunopathol. 126: 171-198 (2008).
-
Alvaro A, Rosales R, Masana L, Vallve JC. Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids.
J. Nutr. Biochem. May 13 [Epub ahead of print] (2009).
*
-
Alwayn IP, Andersson C, Lee S, Arsenault DA, Bistrian B, Gura KM, Nose V, Zauscher B, Moses MA, Puder M. Inhibition of matrix metalloproteinases increases PPAR-alpha and IL-6 and prevents dietary-induced hepatic steatosis and injury in a murine model.
Am. J. Physiol. Gastrointest. Liver Physiol. 291: G1011-G1019 (2006).
*
-
Aly HH, Shimotohno K, Hijikata M. 3D cultured immortalized human hepatocytes useful to develop drugs for blood-borne HCV.
Biochem. Biophys. Res. Commun. 379: 330-334 (2009).
*
-
Amador-Noguez D, Dean A, Huang W, Setchell K, Moore D, Darlington G. Alterations in xenobiotic metabolism in the long-lived Little mice.
Aging Cell 6: 453-470 (2007).
*
-
Amanatidou V, Sourvinos G, Apostolakis S, Neonaki P, Tsilimigaki A, Krambovitis E, Spandidos DA. RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis.
Pediatr. Infect. Dis. J. 27: 38-42 (2008).
-
Amann-Zalcenstein D, Avidan N, Kanyas K, Ebstein RP, Kohn Y, Hamdan A, Ben-Asher E, Karni O, Mujaheed M, Segman RH, Maier W, Macciardi F, Beckmann JS, Lancet D, Lerer B. AHI1, a pivotal neurodevelopmental gene, and C6orf217 are associated with susceptibility to schizophrenia.
Eur. J. Hum. Genet. 14: 1111-1119 (2006).
*
-
Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M. Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells.
J. Steroid Biochem. Mol. Biol. 114: 144-151 (2009).
-
Amaral JD, Castro RE, Sola S, Steer CJ, Rodrigues CM. p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis.
J. Biol. Chem. 282: 34250-34259 (2007).
*
-
Amaral JD, Sola S, Steer CJ, Rodrigues CM. Role of nuclear steroid receptors in apoptosis.
Curr. Med. Chem. 16: 3886-3902 (2009).
-
Amaral MD, Clarke LA, Ramalho AS, Beck S, Broackes-Carter F, Rowntree R, Mouchel N, Williams SH, Harris A, Tzetis M, Steiner B, Sanz J, Gallati S, Nissim-Rafinifa M, Kerem B, Hefferon T, Cutting GR, Goina E, Pagani F. Quantitative methods for the analysis of CFTR transcripts/splicing variants.
J. Cyst. Fibros. 3 Suppl. 2: 17-23 (2004).
-
Amarapurkar AD, Amarapurkar DN, Vibhav S, Patel ND. Angiogenesis in chronic liver disease.
Ann. Hepatol. 6: 170-173 (2007).
*
-
Amarnath S, Dong L, Li J, Wu Y, Chen W. Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells.
Retrovirology 4: 57 (2007).
-
Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD. Cytokine-dependent transcriptional down-regulation of epithelial sodium channel in ulcerative colitis.
Gastroenterology 126: 1711-1720 (2004).
*
-
Ambati S, Duan J, Choi YH, Hartzell DL, Della-Fera MA, Baile CA. ICV vs. VMH injection of leptin: comparative effects on hypothalamic gene expression.
Behav. Brain Res. 196: 279-285 (2009).
-
Ambort D, Brellier F, Becker-Pauly C, Stocker W, Andrejevic-Blant S, Chiquet M, Sterchi EE. Specific processing of tenascin-C by the metalloprotease meprinbeta neutralizes its inhibition of cell spreading.
Matrix Biol. Sep 10 [Epub ahead of print] (2009).
-
Ambrogini E, Toraldo G, Marcocci C. Post-menopausal osteoporosis: is it an autoimmune disease?
J. Endocrinol. Invest. 28: S43-S47 (2005).
-
Ameen C, Edvardsson U, Ljungberg A, Asp L, Akerblad P, Tuneld A, Olofsson SO, Linden D, Oscarsson J. Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver.
J. Biol. Chem. 280: 1224-1229 (2005).
*
-
Ameen N, Alexis J, Salas P. Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract.
Histochem. Cell Biol. 114: 69-75 (2000).
*
-
Amela-Peris R, Aladro Y, Conde-Sendin MA, Alemany-Rodriguez MJ, Munoz-Fernandez C, Reyes-Yanez MP, Deniz-Naranjo MC, Sanchez-Garcia F. Familial multiple sclerosis in Canary Islands.
Rev. Neurol. 39: 911-914 (2004).
-
Amelie P, Claudine R, Sophie L, Andre G, Fabrice M. Involvement of pregnane X receptor in the regulation of CYP2B6 gene expression by oltipraz in human hepatocytes.
Toxicol In Vitro Oct 12 [Epub ahead of print] (2009).
-
Amemiya H, Kono H, Fujii H. Liver regeneration is impaired in macrophage colony stimulating factor deficient mice after partial hepatectomy: the role of M-CSF-induced macrophages.
J. Surg. Res. Sep 11 [Epub ahead of print] (2009).
*
-
Amend B, Doster H, Lange C, Dubois E, Kalbacher H, Melms A, Bischof F. Induction of autoimmunity by expansion of autoreactive CD4+CD62Llow cells in vivo.
J. Immunol. 177: 4384-4390 (2006).
*
-
Amengual J, Ribot J, Bonet ML, Palou A. Retinoic acid treatment increases lipid oxidation capacity in skeletal muscle of mice.
Obesity (Silver Spring) 16: 585-591 (2008).
*
-
Amiel E, Alonso A, Uematsu S, Akira S, Poynter ME, Berwin B. Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis.
J. Leukoc. Biol. 85: 595-605 (2009).
*
-
Amigo L, Castro J, Miquel JF, Zanlungo S, Young SG, Nervi F. Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones.
Gastroenterology 131: 1870-1878 (2006).
*
-
Amin AR, Patel RN, Thakker GD, Lowenstein CJ, Attur MG, Abramson SB. Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines.
FEBS Lett. 410: 259-264 (1997).
-
Amin MR, Malakooti J, Sandoval R, Dudeja PK, Ramaswamy K. IFN-gamma and TNF-alpha regulate the human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line, C2BBe1.
Am. J. Physiol. Cell Physiol. 291: C887-C896 (2006).
*
-
Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, Mills GB, Domany E, Yarden Y. A module of negative feedback regulators defines growth factor signaling.
Nat. Genet. 39: 503-512 (2007).
*
-
Amit I, Garber M, Chevrier N, Leite AP, Donner Y, Eisenhaure T, Guttman M, Grenier JK, Li W, Zuk O, Schubert LA, Birditt B, Shay T, Goren A, Zhang X, Smith Z, Deering R, McDonald RC, Cabili M, Bernstein BE, Rinn JL, Meissner A, Root DE, Hacohen N, Regev A. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses.
Science 326: 257-263 (2009).
*
-
Amit-Romach E, Uni Z, Cheled S, Berkovich Z, Reifen R. Bacterial population and innate immunity-related genes in rat gastrointestinal tract are altered by vitamin A-deficient diet.
J. Nutr. Biochem. 20: 70-77 (2009).
*
-
Amit-Romach E, Uni Z, Reifen R. Multistep mechanism of probiotic bacterium, the effect on innate immune system.
Mol. Nutr. Food Res. Dec 8 [Epub ahead of print] (2009).
*
-
Amoli MM, Salway F, Ollier WE, Gonzalez-Gay MA. MCP-1 gene haplotype association in biopsy proven giant cell arteritis.
J. Rheumatol. 32: 507-510 (2005).
-
Amoruso A, Bardelli C, Fresu LG, Palma A, Vidali M, Ferrero V, Ribichini F, Vassanelli C, Brunelleschi S. Enhanced PPAR-gamma expression in monocyte/macrophages from coronary artery disease patients and possible gender differences.
J. Pharmacol. Exp. Ther. 331: 531-538 (2009).
*
-
Amsaguine-Safir S, Bianchi A, Collet P, Huin-Schohn C, Jeanvoine A, Becuwe P, Kremarik-Bouillaud P, Domenjoud L, Keller JM, Schohn H, Dauca M. Induction of the expression of the peroxisome proliferator-activated receptor alpha (PPARalpha) by clofibrate in jerboa tissues.
Microsc. Res. Tech. 61: 185-190 (2003).
*
-
Amsen D, Spilianakis CG, Flavell RA. How are T(H)1 and T(H)2 effector cells made?
Curr. Opin. Immunol. 21: 153-160 (2009).
-
An F, Li Q, Tu Z, Bu H, Chan CC, Caspi RR, Lin F. Role of DAF in protecting against T-cell autoreactivity that leads to experimental autoimmune uveitis.
Invest. Ophthalmol. Vis. Sci. 50: 3778-3782 (2009).
-
An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X. SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production.
Immunity 25: 919-928 (2006).
*
-
An P, Thio CL, Kirk GD, Donfield S, Goedert JJ, Winkler CA. Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance.
J. Infect. Dis. 198: 1159-1165 (2008).
*
-
Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW. Gender dictates the nuclear receptor mediated regulation of CYP3A44.
Drug Metab. Dispos. 35: 36-42 (2007).
*
-
Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11.
Pharmacogenomics J. 4: 91-101 (2004).
*
-
Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors.
FASEB J. 17: 1736-1738 (2003).
*
-
Anandarajah AP, Ritchlin CT. The diagnosis and treatment of early psoriatic arthritis.
Nat. Rev. Rheumatol. 5: 634-641 (2009).
-
Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor.
J. Biol. Chem. 276: 28857-28865 (2001).
*
-
Anapolsky A, Teng S, Dixit S, Piquette-Miller M. The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and metabolizing enzymes in mice.
Drug Metab. Dispos. 34: 405-409 (2006).
*
-
Anchang B, Sadeh MJ, Jacob J, Tresch A, Vlad MO, Oefner PJ, Spang R. Special feature: modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models.
Proc. Natl. Acad. Sci. U.S.A. 106: 6447-6452 (2009).
*
-
Andersen J, Vanscoy S, Cheng TF, Gomez D, Reich NC. IRF-3-dependent and augmented target genes during viral infection.
Genes Immun. 9: 168-175 (2008).
*
-
Andersen JB, Loi R, Perra A, Factor VM, Ledda-Columbano GM, Columbano A, Thorgeirsson SS. Progenitor-derived hepatocellular carcinoma model in the rat.
Hepatology Dec 4 [Epub ahead of print] (2009).
*
-
Andersen MH, Schrama D, Thor Straten P, Becker JC. Cytotoxic T cells.
J. Invest. Dermatol. 126: 32-41 (2006).
*
-
Andersen RS, Sorensen RB, Andersen MH, Straten PT. CD8 T-cell responses against cyclin B1.
Clin. Cancer Res. 15: 7106-7107 (2009). *
-
Anderson GG, Moreau-Marquis S, Stanton BA, O'Toole GA. In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells.
Infect. Immun. 76: 1423-1433 (2008).
*
-
Anderson GG, Yahr TL, Lovewell RR, O'Toole GA. The Pseudomonas aeruginosa magnesium transporter MgtE inhibits transcription of the type III secretion system.
Infect. Immun. Dec 22 [Epub ahead of print] (2009).
*
-
Anderson GJ, Frazer DM, McLaren GD. Iron absorption and metabolism.
Curr. Opin. Gastroenterol. 25: 129-135 (2009).
-
Anderson JP, Mueller JL, Rosengren S, Boyle DL, Schaner P, Cannon SB, Goodyear CS, Hoffman HM. Structural, expression, and evolutionary analysis of mouse CIAS1.
Gene 338: 25-34 (2004).
*
-
Anderson MK. At the crossroads: diverse roles of early thymocyte transcriptional regulators.
Immunol. Rev. 209: 191-211 (2006).
-
Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance.
Immunity 23: 227-239 (2005).
*
-
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein.
Science 298: 1395-1401 (2002).
*
-
Anderson SK, Dewar K, Goulet ML, Leveque G, Makrigiannis AP. Complete elucidation of a minimal class I MHC natural killer cell receptor haplotype.
Genes Immun. 6: 481-492 (2005).
*
-
Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, Steffensen KR, Chandraratna RA, Gustafsson JA, Corton JC. Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor and liver X receptor in mouse liver.
Mol. Pharmacol. 66: 1440-1452 (2004).
*
-
Anderson SP, Dunn CS, Cattley RC, Corton JC. Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling.
Carcinogenesis 22: 1843-1851 (2001).
*
-
Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, Kwak MK, Kensler TW, Corton JC. The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes.
J. Biol. Chem. 279: 52390-52398 (2004).
*
-
Anderson SP, Yoon L, Richard EB, Dunn CS, Cattley RC, Corton JC. Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice.
Hepatology 36: 544-554 (2002).
*
-
Andersson D, Kotarsky K, Wu J, Agace W, Duan RD. Expression of alkaline sphingomyelinase in yeast cells and anti-inflammatory effects of the expressed enzyme in a rat colitis model.
Dig. Dis. Sci. 54: 1440-1448 (2009).
*
-
Andersson HA, Passeri MF, Barry MA. Rad23 as a reciprocal agent for stimulating or repressing immune responses.
Hum. Gene Ther. 16: 634-641 (2005).
-
Andersson J, Tran DQ, Pesu M, Davidson TS, Ramsey H, O'Shea JJ, Shevach EM. CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner.
J. Exp. Med. 205: 1975-1981 (2008).
*
-
Andersson U, Harris HE. The role of HMGB1 in the pathogenesis of rheumatic disease.
Biochim. Biophys. Acta 1799: 141-148 (2010).
*
-
Andersson U, Tracey KJ. HMGB1 in sepsis.
Scand. J. Infect. Dis. 35: 577-584 (2003).
-
Ando H, Tsuruoka S, Yamamoto H, Takamura T, Kaneko S, Fujimura A. Effects of pravastatin on the expression of ATP-binding cassette transporter A1.
J. Pharmacol. Exp. Ther. 311: 420-425 (2004).
*
-
Ando T, Nobata K, Watanabe O, Ina K, Kusugami K, Maeda O, Ishiguro K, Ohmiya N, Niwa Y, Goto H. Abnormalities in the upper gastrointestinal tract in inflammatory bowel disease.
Inflammopharmacology 15: 101-104 (2007).
-
Ando T, Watanabe O, Ishiguro K, Maeda O, Ishikawa D, Minami M, Hasegawa M, Kondo S, Goto Y, Ohmiya N, Niwa Y, Goto H. Relationships between Helicobacter pylori infection status, endoscopic, histopathological findings, and cytokine production in the duodenum of Crohn's disease patients.
J. Gastroenterol. Hepatol. 23 Suppl. 2: S193-S197 (2008).
*
-
Andoh A, Fujino S, Bamba S, Araki Y, Okuno T, Bamba T, Fujiyama Y. IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts.
J. Immunol. 169: 1683-1687 (2002).
*
-
Andoh A, Fujino S, Hirai Y, Fujiyama Y. Epimorphin expression in human colonic myofibroblasts.
Int. J. Mol. Med. 13: 57-61 (2004).
-
Andoh A, Shioya M, Nishida A, Bamba S, Tsujikawa T, Kim-Mitsuyama S, Fujiyama Y. Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease.
J. Immunol. 183: 687-695 (2009).
-
Andrade RJ, Lucena MI, Alonso A, Garcia-Cores M, Garcia-Ruiz E, Benitez R, Fernandez MC, Pelaez G, Romero M, Corpas R, Duran JA, Jimenez M, Rodrigo L, Nogueras F, Martin-Vivaldi R, Navarro JM, Salmeron J, de la Cuesta FS, Hidalgo R. HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease.
Hepatology 39: 1603-1612 (2004).
*
-
Andrade WA, Silva AM, Alves VS, Salgado AP, Melo MB, Andrade HM, Dall'orto FV, Garcia SA, Silveira TN, Gazzinelli RT. Early endosome localization and activity of RasGEF1b, a Toll-like receptor-inducible Ras guanine-nucleotide exchange factor.
Genes Immun. Jan 21 [Epub ahead of print] (2010).
-
Andrassy M, Igwe J, Autschbach F, Volz C, Remppis A, Neurath MF, Schleicher E, Humpert PM, Wendt T, Liliensiek B, Morcos M, Schiekofer S, Thiele K, Chen J, Kientsch-Engel R, Schmidt AM, Stremmel W, Stern DM, Katus HA, Nawroth PP, Bierhaus A. Posttranslationally modified proteins as mediators of sustained intestinal inflammation.
Am. J. Pathol. 169: 1223-1237 (2006).
*
-
Andrault JB, Gaillard I, Giorgi D, Rouquier S. Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides.
Genomics 82: 172-184 (2003).
*
-
Andre J, Cimaz R, Ranchin B, Galambrun C, Bertrand Y, Bouvier R, Rieux-Laucat F, Trescol-Biemont MC, Cochat P, Bonnefoy-Berard N. Overexpression of the antiapoptotic gene Bfl-1 in B cells from patients with familial systemic lupus erythematosus.
Lupus 16: 95-100 (2007).
*
-
Andre MF, Aumaitre O, Grateau G, Chamaillard M, Costedoat-Chalumeau N, Cardoso MC, Henry-Berger J, Ramakrishna BS, Delpech M, Piette JC, Creveaux I. Longest form of CCTG microsatellite repeat in the promoter of the CD2BP1/PSTPIP1 gene is associated with aseptic abscesses and with Crohn disease in French patients.
Dig. Dis. Sci. Sep 3 [Epub ahead of print] (2009).
*
-
Andre MF, Aumaitre O, Piette JC, Grateau G, Cardoso MC, Ouchchane L, Kemeny JL, Dastugue B, Delpech M, Creveaux I. Analysis of the NOD2/CARD15 gene in patients affected with the aseptic abscesses syndrome with or without inflammatory bowel disease.
Dig. Dis. Sci. 53: 490-499 (2008).
*
-
Andreakos E, Foxwell B, Feldmann M. Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?
Immunol. Rev. 202: 250-265 (2004).
*
-
Andreakos E, Sacre S, Foxwell BM, Feldmann M. The Toll-like receptor-nuclear factor kappaB pathway in rheumatoid arthritis.
Front. Biosci. 10: 2478-2488 (2005).
-
Andreas K, Haupl T, Lubke C, Ringe J, Morawietz L, Wachtel A, Sittinger M, Kaps C. Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.
Arthritis Res. Ther. 11: R15 (2009).
*
-
Andreas K, Luebke C, Haeupl T, Dehne T, Morawietz L, Ringe J, Kaps C, Sittinger M. Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study.
Arthritis Res. Ther. 10: R9 (2008).
*
-
Andreasen C, Powell DA, Carbonetti NH. Pertussis toxin stimulates IL-17 production in response to Bordetella pertussis infection in mice.
PLoS One 4: e7079 (2009).
*
-
Andreeva-Gateva P. Peroxisome proliferator activated receptors PPARs: their role in carbohydrate and lipid metabolism.
Ann. Biol. Clin. (Paris) 61: 295-303 (2003).
-
Andrejko KM, Raj NR, Kim PK, Cereda M, Deutschman CS. IL-6 modulates sepsis-induced decreases in transcription of hepatic organic anion and bile acid transporters.
Shock 29: 490-496 (2008).
*
-
Andres D, Bautista M, Cascales M. Attenuation of cyclosporine A toxicity by sublethal heat shock. Role of catalase.
Biochem. Pharmacol. 69: 493-501 (2005).
*
-
Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine.
J. Immunol. 164: 6303-6312 (2000).
*
-
Andresen L, Jorgensen VL, Perner A, Hansen A, Eugen-Olsen J, Rask-Madsen J. Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis.
Gut 54: 503-509 (2005).
*
-
Andrews E, Armstrong M, Tugwood J, Swan D, Glaves P, Pirmohamed M, Aithal GP, Wright MC, Day CP, Daly AK. A role for the pregnane X receptor in flucloxacillin-induced liver injury.
Hepatology [In Press] (2010). *
-
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism.
Nat. Genet. 41: 482-487 (2009).
*
-
Androulidaki A, Iliopoulos D, Arranz A, Doxaki C, Schworer S, Zacharioudaki V, Margioris AN, Tsichlis PN, Tsatsanis C. The kinase Akt1 controls macrophage response to lipopolysaccharide by regulating microRNAs.
Immunity 31: 220-231 (2009).
*
-
Andrulionyte L, Peltola P, Chiasson JL, Laakso M. Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial.
Diabetes 55: 2148-2152 (2006).
*
-
Aneja RK, Tsung A, Sjodin H, Gefter JV, Delude RL, Billiar TR, Fink MP. Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance.
J. Leukoc. Biol. 84: 1326-1334 (2008).
*
-
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression.
Nature 423: 659-663 (2003).
*
-
Anetor JI, Ajose F, Anetor GO, Iyanda AA, Babalola OO, Adeniyi FA. High cadmium/zinc ratio in cigarette smokers:potential implications as a biomarker of risk of prostate cancer.
Niger J. Physiol. Sci. 23: 41-49 (2008).
-
Anezaki Y, Ohshima S, Ishii H, Kinoshita N, Dohmen T, Kataoka E, Sato W, Iizuka M, Goto T, Sasaki J, Sasaki T, Suzuki A, Ohnishi H, Horie Y. Sex difference in the liver of hepatocyte-specific Pten-deficient mice: a model of nonalcoholic steatohepatitis.
Hepatol. Res. 39: 609-618 (2009).
*
-
Ang DK, Brodnicki TC, Jordan MA, Wilson WE, Silveira P, Gliddon BL, Baxter AG, van Driel IR. Two genetic loci independently confer susceptibility to autoimmune gastritis.
Int. Immunol. 19: 1135-1144 (2007).
*
-
Angelo G, Lamon-Fava S, Sonna LA, Lindauer ML, Wood RJ. Heat shock protein 90beta: a novel mediator of vitamin D action.
Biochem. Biophys. Res. Commun. 367: 578-583 (2008).
*
-
Anger T, Ekici AB, Daniel WG, Garlichs CD. Gene polymorphisms leading to calcified and stenotic aortic valves.
Herz. 31: 635-643 (2006).
-
Angers I, Sancho-Shimizu V, Descoteaux A, Gewirtz AT, Malo D. Tlr5 is not primarily associated with susceptibility to Salmonella typhimurium infection in MOLF/Ei mice.
Mamm. Genome 17: 385-397 (2006).
*
-
Anghel SI, Wahli W. Fat poetry: a kingdom for PPARgamma.
Cell Res. 17: 486-511 (2007).
*
-
Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling.
Nat. Immunol. Feb 14 [Epub ahead of print] (2010).
*
-
Anglicheau D, Thervet E, Etienne I, Hurault De Ligny B, Le Meur Y, Touchard G, Buchler M, Laurent-Puig P, Tregouet D, Beaune P, Daly A, Legendre C, Marquet P. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation.
Clin. Pharmacol. Ther. 75: 422-433 (2004).
*
-
Anheim M, Degos B, Echaniz-Laguna A, Fleury M, Grucker M, Tranchant C. Ataxia associated with gluten sensitivity, myth or reality?
Rev. Neurol. (Paris) 162: 214-221 (2006).
-
Anilkumar N, Weber R, Zhang M, Brewer A, Shah AM. Nox4 and Nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation.
Arterioscler. Thromb. Vasc. Biol. 28: 1347-1354 (2008).
-
Anjos S, Polychronakos C. Mechanisms of genetic susceptibility to type I diabetes: beyond HLA.
Mol. Genet. Metab. 81: 187-195 (2004).
*
-
Anjos SM, Tessier MC, Polychronakos C. Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block.
J. Clin. Endocrinol. Metab. 89: 6257-6265 (2004).
*
-
Annereau JP, Szakacs G, Tucker CJ, Arciello A, Cardarelli C, Collins J, Grissom S, Zeeberg B, Reinhold W, Weinstein J, Pommier Y, Paules RS, Gottesman MM. Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance.
Mol. Pharmacol. 66: 1397-1405 (2004).
*
-
Annese V, Valvano MR, Palmieri O, Latiano A, Bossa F, Andriulli A. Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.
World J. Gastroenterol. 12: 3636-3644 (2006).
*
-
Annibali V, Giovanni SD, Cannoni S, Giugni E, Bomprezzi R, Mattei C, Elkahloun A, Coccia EM, Alfo M, Orzi F, Ristori G, Salvetti M. Gene expression profiles reveal homeostatic dynamics during interferon-beta therapy in multiple sclerosis.
Autoimmunity 40: 16-22 (2007).
-
Annilo T, Chen ZQ, Shulenin S, Dean M. Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.
Mamm. Genome 14: 7-20 (2003).
*
-
Annilo T, Dean M. Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages.
Genomics 84: 34-46 (2004).
*
-
Annilo T, Tammur J, Hutchinson A, Rzhetsky A, Dean M, Allikmets R. Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4.
Cytogenet. Cell. Genet. 94: 196-201 (2001).
-
Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. The immune response to lentiviral-delivered transgene is modulated in vivo by transgene expressing antigen presenting cells but not by CD4+CD25+ regulatory T cells.
Blood 110: 1788-1796 (2007).
*
-
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, Parente E, Filì L, Ferri S, Frosali F, Giudici F, Romagnani P, Parronchi P, Tonelli F, Maggi E, Romagnani S. Phenotypic and functional features of human Th17 cells.
J. Exp. Med. 204: 1849-1861 (2007).
*
-
Anolik JH. B cell biology and dysfunction in SLE.
Bull. N.Y.U. Hosp. Jt. Dis. 65: 182-186 (2007).
*
-
Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility.
Annu. Rev. Immunol. 24: 607-656 (2006).
*
-
Anson DS, Smith GJ, Parsons DW. Gene therapy for cystic fibrosis airway disease- is clinical success imminent?
Curr. Gene Ther. 6: 161-179 (2006).
-
Anstee QM, Wright M, Goldin R, Thursz MR. Parenchymal extinction: coagulation and hepatic fibrogenesis.
Clin. Liver Dis. 13: 117-126 (2009).
-
Antes TJ, Levy-Wilson B. HNF-3 beta, C/EBP beta, and HNF-4 act in synergy to enhance transcription of the human apolipoprotein B gene in intestinal cells.
DNA Cell Biol. 20: 67-74 (2001).
-
Anthoni C, Laukoetter MG, Rijcken E, Vowinkel T, Mennigen R, Muller S, Senninger N, Russell J, Jauch J, Bergmann J, Granger DN, Krieglstein CF. Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis.
Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1131-G1137 (2006).
*
-
Anthoni H, Zucchelli M, Matsson H, Muller-Myhsok B, Fransson I, Schumacher J, Massinen S, Onkamo P, Warnke A, Griesemann H, Hoffmann P, Nopola-Hemmi J, Lyytinen H, Schulte-Korne G, Kere J, Nothen MM, Peyrard-Janvid M. A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.
Hum. Mol. Genet. 16: 667-677 (2007).
*
-
Anthonisen EH, Berven L, Holm S, Nygard M, Nebb HI, Gronning-Wang LM. The nuclear receptor LXR is O-GlcNAc modified in response to glucose.
J. Biol. Chem. Nov 20 [Epub ahead of print] (2009).
*
-
Antille C, Frei M, Sorg O, Tran C, Kaya G, Masouye I, Fontao L, Prins C, Saurat JH. Amicrobial pustulosis of the folds associated with auto-immune disorders. A case report with an analysis of cytokine expression profile in skin lesions of cutaneous neutrophilic lupus.
Dermatology 216: 324-329 (2008).
-
Antoniades A, Kalvari I, Pattichis C, Jones N, Matthews PM, Domenici E, Muglia P. Discovering genetic polymorphism associated with gene expression levels across the whole genome.
Conf. Proc. IEEE Eng. Med. Biol. Soc. 1: 5466-5469 (2009).
*
-
Antoniazi S, Price HP, Kropf P, Freudenberg MA, Galanos C, Smith DF, Muller I. Chemokine gene expression in Toll-like receptor-competent and -deficient mice infected with Leishmania major.
Infect. Immun. 72: 5168-5174 (2004).
*
-
Antonicelli R, Olivieri F, Cavallone L, Spazzafumo L, Bonafe M, Marchegiani F, Cardelli M, Galeazzi R, Giovagnetti S, Perna GP, Franceschi C. Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers.
Coron. Artery Dis. 16: 489-493 (2005).
-
Antonioli L, Fornai M, Colucci R, Ghisu N, Tuccori M, Del Tacca M, Blandizzi C. Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases.
Inflamm. Bowel Dis. 14: 566-574 (2008).
*
-
Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9.
Gastroenterology 136: 2325-2333 (2009).
*
-
Antoniv TT, Ivashkiv LB. Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages.
Arthritis Rheum. 54: 2711-2721 (2006).
*
-
Antonson P, Jakobsson T, Almlof T, Guldevall K, Steffensen KR, Gustafsson JA. RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with SMAD2 and SMAD3.
J. Biol. Chem. 283: 8995-9001 (2008).
*
-
Antony JM, Ellestad KK, Hammond R, Imaizumi K, Mallet F, Warren KG, Power C. The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes.
J. Immunol. 179: 1210-1224 (2007).
*
-
Antony JM, Izad M, Bar-Or A, Warren KG, Vodjgani M, Mallet F, Power C. Quantitative analysis of human endogenous retrovirus-W env in neuroinflammatory diseases.
AIDS Res. Hum. Retroviruses 22: 1253-1259 (2006).
-
Antony JM, Zhu Y, Izad M, Warren KG, Vodjgani M, Mallet F, Power C. Comparative expression of human endogenous retrovirus-W genes in multiple sclerosis.
AIDS Res. Hum. Retroviruses 23: 1251-1256 (2007).
-
Antonyak MA, Li B, Regan AD, Feng Q, Dusaban SS, Cerione RA. Tissue transglutaminase is an essential participant in the epidermal growth factor-stimulated signaling pathway leading to cancer cell migration and invasion.
J. Biol. Chem. 284: 17914-17925 (2009).
*
-
Antoun J, Amet Y, Simon B, Dreano Y, Corlu A, Corcos L, Salaun JP, Plee-Gautier E. CYP4A11 is repressed by retinoic acid in human liver cells.
FEBS Lett. 580: 3361-3367 (2006).
*
-
Antoun J, Goulitquer S, Amet Y, Dreano Y, Salaun JP, Corcos L, Plee-Gautier E. CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis.
J. Lipid Res. 49: 2135-2141 (2008).
*
-
Anuchapreeda S, Thanarattanakorn P, Sittipreechacharn S, Tima S, Chanarat P, Limtrakul P. Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells.
Arch. Pharm. Res. 29: 866-873 (2006).
-
Anz D, Koelzer VH, Moder S, Thaler R, Schwerd T, Lahl K, Sparwasser T, Besch R, Poeck H, Hornung V, Hartmann G, Rothenfusser S, Bourquin C, Endres S. Immunostimulatory RNA blocks suppression by regulatory T cells.
J. Immunol. 184: 939-946 (2010).
-
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T, Yamanaka S. Generation of pluripotent stem cells from adult mouse liver and stomach cells.
Science 321: 699-702 (2008).
*
-
Aoki CA, Dawson K, Kenny TP, Gershwin ME, Bowlus CL. Gene expression by PBMC in primary sclerosing cholangitis: evidence for dysregulation of immune mediated genes.
Clin. Dev. Immunol. 13: 265-271 (2006).
*
-
Aoki T. Genetic disorders of copper transport - diagnosis and new treatment for the patients of Wilson's disease.
No To Hattatsu 37: 99-109 (2005).
-
Aouabdi S, Gibson GG, Plant N. Transcriptional regulation of the PXR gene: identification and characterization of a functional PPARalpha-binding site within the proximal promoter of the PXR gene.
Drug Metab. Dispos. 34: 138-144 (2006).
*
-
Aouacheria A, Navratil V, Lopez-Perez R, Gutierrez NC, Churkin A, Barash D, Mouchiroud D, Gautier C. In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions.
BMC Genomics 8: 2 (2007).
*
-
Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation.
Nature 458: 1180-1184 (2009).
*
-
Aoudjit F, Brochu N, Morin N, Poulin G, Stratowa C, Audette M. Heterodimeric retinoic acid receptor-beta and retinoid X receptor-alpha complexes stimulate expression of the intercellular adhesion molecule-1 gene.
Cell Growth Differ. 6: 515-521 (1995).
-
Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S. Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice.
Hepatology 49: 1636-1644 (2009).
-
Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha).
J. Biol. Chem. 273: 5678-5684 (1998).
*
-
Apel W, Bock R. Enhancement of carotenoid biosynthesis in transplastomic tomatoes by induced lycopene-to-provitamin A conversion.
Plant Physiol. 151: 59-66 (2009).
*
-
Apoil PA, Kuhlein E, Robert A, Rubie H, Blancher A. HIGM syndrome caused by insertion of an AluYb8 element in exon 1 of the CD40LG gene.
Immunogenetics 59: 17-23 (2007).
*
-
Apostolaki M, Manoloukos M, Roulis M, Wurbel MA, Muller W, Papadakis KA, Kontoyiannis DL, Malissen B, Kollias G. Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease.
Gastroenterology 134: 2025-2035 (2008).
*
-
Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N, Amalfitano A. Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo.
J. Immunol. 181: 2134-2144 (2008).
*
-
Apps R, Murphy SP, Fernando R, Gardner L, Ahad T, Moffett A. Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies.
Immunology 127: 26-39 (2009).
*
-
Apte UM, Banerjee A, McRee R, Wellberg E, Ramaiah SK. Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis.
Toxicol. Appl. Pharmacol. 207: 25-38 (2005).
*
-
Aptsiauri N, Carretero R, Garcia-Lora A, Real LM, Cabrera T, Garrido F. Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations.
Cancer Immunol. Immunother. 57: 1727-1733 (2008).
-
Aquino JB, Marmigere F, Lallemend F, Lundgren TK, Villar MJ, Wegner M, Ernfors P. Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues.
Gene Expr. Patterns 8: 217-226 (2008).
-
Ara AI, Xia M, Ramani K, Mato JM, Lu SC. S-Adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation.
Hepatology 47: 1655-1666 (2008).
*
-
Arabzadeh A, Troy TC, Turksen K. Changes in the distribution pattern of claudin tight junction proteins during the progression of mouse skin tumorigenesis.
BMC Cancer 7: 196 (2007).
*
-
Arachchige PG, Takahashi Y, Ide T. Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in rats.
Metabolism 55: 381-390 (2006).
*
-
Arad G, Hillman D, Levy R, Kaempfer R. Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock.
J. Leukoc. Biol. 69: 921-927 (2001).
*
-
Arafat HA, Lada E, Katakam AK, Amin N. Osteopontin deficiency impacts the pancreatic TH1/TH2 cytokine profile following multiple low dose streptozotocin-induced diabetes.
Exp. Clin. Endocrinol. Diabetes 114: 555-562 (2006).
-
Arai T, Kaneko H, Ohnishi H, Matsui E, Fukao T, Kawamoto N, Kasahara K, Kondo N. Hypothermia augments NF-kappaB activity and the production of IL-12 and IFN-gamma.
Allergol. Int. 57: 331-338 (2008).
*
-
Arai T, Kim HJ, Chiba H, Matsumoto A. Interaction of fenofibrate and fish oil in relation to lipid metabolism in mice.
J. Atheroscler. Thromb. 16: 283-291 (2009).
*
-
Arai T, Kim HJ, Chiba H, Matsumoto A. Anti-obesity effect of fish oil and fish oil-fenofibrate combination in female KK mice.
J. Atheroscler. Thromb. 16: 674-683 (2009).
-
Arakaki A, Ooya K, Akiyama Y, Hosokawa M, Komiyama M, Iizuka A, Yamaguchi K, Matsunaga T. TCR-beta repertoire analysis of antigen-specific single T cells using a high-density microcavity array.
Biotechnol. Bioeng. Jan 13 [Epub ahead of print] (2010).
*
-
Araki M, Chung D, Liu S, Rainbow DB, Chamberlain G, Garner V, Hunter KM, Vijayakrishnan L, Peterson LB, Oukka M, Sharpe AH, Sobel R, Kuchroo VK, Wicker LS. Genetic evidence that the differential expression of the ligand-independent isoform of CTLA-4 is the molecular basis of the Idd5.1 type 1 diabetes region in nonobese diabetic mice.
J. Immunol. 183: 5146-5157 (2009).
-
Araki M, Nozaki Y, Motojima K. Transcriptional regulation of metabolic switching PDK4 gene under various physiological conditions.
Yakugaku Zasshi 127: 153-162 (2007).
-
Araki Y, Wang Z, Zang C, Wood WH 3rd, Schones D, Cui K, Roh TY, Lhotsky B, Wersto RP, Peng W, Becker KG, Zhao K, Weng NP. Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8(+) T cells.
Immunity 30: 912-925 (2009).
*
-
Arakura F, Hida S, Ichikawa E, Yajima C, Nakajima S, Saida T, Taki S. Genetic control directed toward spontaneous IFN-alpha/IFN-beta responses and downstream IFN-gamma expression influences the pathogenesis of a murine psoriasis-like skin disease.
J. Immunol. 179: 3249-3257 (2007).
*
-
Aranami T, Yamamura T. Th17 cells and autoimmune encephalomyelitis (EAE/MS).
Allergol. Int. 57: 115-120 (2008).
*
-
Arancibia SA, Beltran CJ, Aguirre IM, Silva P, Peralta AL, Malinarich F, Hermoso MA. Toll-like receptors are key participants in innate immune responses.
Biol. Res. 40: 97-112 (2007).
*
-
Aranda A, Pascual A. Nuclear hormone receptors and gene expression.
Physiol. Rev. 81: 1269-1304 (2001).
*
-
Aranda V, Martinez I, Melero S, Lecanda J, Banales JM, Prieto J, Medina JF. Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes.
Biochem. Biophys. Res. Commun. 319: 1040-1046 (2004).
*
-
Aranyi T, Ratajewski M, Bardoczy V, Pulaski L, Bors A, Tordai A, Varadi A. Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.
J. Biol. Chem. 280: 18643-18550 (2005).
*
-
Aravalli RN, Hu S, Lokensgard JR. Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia.
J. Neuroinflammation 4: 11 (2007).
-
Aravindhan K, Webb CL, Jaye M, Ghosh A, Willette RN, Dinardo NJ, Jucker BM. Assessing the effects of LXR agonists on cellular cholesterol handling: a stable isotope tracer study.
J. Lipid Res. 47: 1250-1260 (2006).
*
-
Archer A, Lauter G, Hauptmann G, Mode A, Gustafsson JA. Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish.
Dev. Dyn. 237: 1090-1098 (2008).
*
-
Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D. A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen.
Gastroenterology 131: 1844-1855 (2006).
*
-
Arcos-Burgos M, Palacio LG, Mora O, Sanchez JL, Jimenez M, Jimenez I. Molecular genetic aspects of the susceptibility to develop idiopathic epilepsy.
Rev. Neurol. 30: 173-177 (2000).
-
Ardeniz O, Avci CB, Sin A, Ozgen G, Gunsar F, Mete N, Gulbahar O, Kokuludag A. Vitamin D deficiency in the absence of enteropathy in three cases with common variable immunodeficiency.
Int. Arch. Allergy Immunol. 147: 74-83 (2008).
-
Ardern-Jones MR, Black AP, Bateman EA, Ogg GS. Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells.
Proc. Natl. Acad. Sci. U.S.A. 104: 5557-5562 (2007).
*
-
Ardizzone S, Maconi G, Bianchi V, Russo A, Colombo E, Cassinotti A, Penati C, Tenchini ML, Bianchi Porro G. Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.
Inflamm. Bowel Dis. 13: 516-523 (2007).
*
-
Arellanes-Garcia L, Bautista N, Mora P, Ortega-Larrocea G, Burguet A, Gorodezky C. HLA-DR is strongly associated with Vogt-Koyanagi-Harada disease in Mexican Mestizo patients.
Ocul. Immunol. Inflamm. 6: 93-100 (1998).
-
Arenas F, Hervias I, Uriz M, Joplin R, Prieto J, Medina JF. Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells.
J. Clin. Invest. 118: 695-709 (2008).
*
-
Arentz-Hansen EH, McAdam SN, Molberg O, Kristiansen C, Sollid LM. Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease.
Gut 46: 46-51 (2000).
*
-
Argent RH, Kidd M, Owen RJ, Thomas RJ, Limb MC, Atherton JC. Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori.
Gastroenterology 127: 514-523 (2004).
*
-
Argmann C, Dobrin R, Heikkinen S, Auburtin A, Pouilly L, Cock TA, Koutnikova H, Zhu J, Schadt EE, Auwerx J. Ppargamma2 is a key driver of longevity in the mouse.
PLoS Genet. 5: e1000752 (2009).
*
-
Argyropoulos C, Nikiforidis GC, Theodoropoulou M, Adamopoulos P, Boubali S, Georgakopoulos TN, Paliogianni F, Papavassiliou AG, Mouzaki A. Mining microarray data to identify transcription factors expressed in naive resting but not activated T lymphocytes.
Genes Immun. 5: 16-25 (2004).
*
-
Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H. Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells.
Proc. Natl. Acad. Sci. U.S.A. 107: 2556-2561 (2010).
*
-
Aricha R, Feferman T, Fuchs S, Souroujon MC. Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis.
J. Immunol. 180: 2132-2139 (2008).
*
-
Arijs I, De Hertogh G, Lemaire K, Quintens R, Van Lommel L, Van Steen K, Leemans P, Cleynen I, Van Assche G, Vermeire S, Geboes K, Schuit F, Rutgeerts P. Mucosal gene expression of antimicrobial peptides in inflammatory bowel disease before and after first infliximab treatment.
PLoS One 4: e7984 (2009).
*
-
Arijs I, Li K, Toedter G, Quintens R, Van Lommel L, Van Steen K, Leemans P, De Hertogh G, Lemaire K, Ferrante M, Schnitzler F, Thorrez L, Ma K, Song XY, Marano C, Van Assche G, Vermeire S, Geboes K, Schuit F, Baribaud F, Rutgeerts P. Mucosal gene signatures to predict response to infliximab in patients with ulcerative colitis.
Gut 58: 1612-1619 (2009).
*
-
Arikan C, Berdeli A, Ozgenc F, Tumgor G, Yagci RV, Aydogdu S. Positive association of macrophage migration inhibitory factor gene-173G/C polymorphism with biliary atresia.
J. Pediatr. Gastroenterol. Nutr. 42: 77-82 (2006).
*
-
Arimilli S, Johnson JB, Clark KM, Graff AH, Alexander-Miller MA, Mizel SB, Parks GD. Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function.
J. Virol. 82: 10975-10985 (2008).
*
-
Arimoto K, Kadowaki N, Ishikawa T, Ichinohe T, Uchiyama T. FOXP3 expression in peripheral blood rapidly recovers and lacks correlation with the occurrence of graft-versus-host disease after allogeneic stem cell transplantation.
Int. J. Hematol. 85: 154-162 (2007).
-
Arimura S, Matsunaga A, Kitamura T, Aoki K, Aoki M, Taketo MM. Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling.
Gastroenterology 137: 629-638 (2009).
*
-
Arina A, Murillo O, Dubrot J, Azpilikueta A, Alfaro C, Perez-Gracia JL, Bendandi M, Palencia B, Hervas-Stubbs S, Melero I. Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer.
Expert Opin. Biol. Ther. 7: 599-615 (2007).
-
Arisawa S, Ishida K, Kameyama N, Ueyama J, Hattori A, Tatsumi Y, Hayashi H, Yano M, Hayashi K, Katano Y, Gotoh H, Takagi K, Wakusawa S. Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells.
Biochem. Pharmacol. 77: 858-866 (2009).
*
-
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Hasegawa S, Takagi T, Wang FY, Hirata I, Nakano H. The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis.
Int. J. Mol. Med. 19: 143-148 (2007).
*
-
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Arima Y, Okubo M, Hirata I, Nakano H. The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium.
Oncol. Rep. 19: 211-216 (2008).
*
-
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Okubo M, Hirata I, Nakano H. Nrf2 gene promoter polymorphism and gastric carcinogenesis.
Hepatogastroenterology 55: 750-754 (2008).
-
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Okubo M, Sakata M, Wang FY, Hirata I, Nakano H. Nrf2 gene promoter polymorphism is associated with ulcerative colitis in a Japanese population.
Hepatogastroenterology 55: 394-397 (2008).
-
Arita M, Clish CB, Serhan CN. The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids.
Biochem. Biophys. Res. Commun. 338: 149-157 (2005).
*
-
Arita M, Yoshida M, Hong S, Tjonahen E, Glickman JN, Petasis NA, Blumberg RS, Serhan CN. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis.
Proc. Natl. Acad. Sci. U.S.A. 102: 7671-7676 (2005).
*
-
Ariyan C, Salvalaggio P, Fecteau S, Deng S, Rogozinski L, Mandelbrot D, Sharpe A, Sayegh MH, Basadonna GP, Rothstein DM. Cutting edge: transplantation tolerance through enhanced CTLA-4 expression.
J. Immunol. 171: 5673-5677 (2003).
*
-
Armaka M, Apostolaki M, Jacques P, Kontoyiannis DL, Elewaut D, Kollias G. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases.
J. Exp. Med. 205: 331-337 (2008).
*
-
Armananzas R, Calvo B, Inza I, Lopez-Hoyos M, Martinez-Taboada V, Ucar E, Bernales I, Fullaondo A, Larranaga P, Zubiaga AM. Microarray analysis of autoimmune diseases by machine learning procedures.
IEEE Trans. Inf. Technol. Biomed. 13: 341-350 (2009).
*
-
Armendariz AD, Krauss RM. Hepatic nuclear factor 1-alpha: inflammation, genetics, and atherosclerosis.
Curr. Opin. Lipidol. 20: 106-111 (2009).
-
Armstrong JL, Redfern CP, Veal GJ. 13-cis Retinoic acid and isomerisation in paediatric oncology - is changing shape the key to success?
Biochem. Pharmacol. 69: 1299-1306 (2005).
*
-
Armstrong-James DP, Turnbull SA, Teo I, Stark J, Rogers NJ, Rogers TR, Bignell E, Haynes K. Impaired interferon-gamma responses, increased interleukin-17 expression, and a tumor necrosis factor-alpha transcriptional program in invasive aspergillosis.
J. Infect. Dis. 200: 1341-1351 (2009).
*
-
Arnesano F, Bertini I. Structural genomics on metalloproteins.
Gene Funct. Dis. 3: 49-55 (2002). *
-
Arnett FC. Genetic studies of human lupus in families.
Int. Rev. Immunol. 19: 297-317 (2000).
-
Arnett FC, Howard RF, Tan F, Moulds JM, Bias WB, Durban E, Cameron HD, Paxton G, Hodge TJ, Weathers PE, Reveille JD. Increased prevalence of systemic sclerosis in a Native American tribe in Oklahoma. Association with an Amerindian HLA haplotype.
Arthritis Rheum. 39: 1362-1370 (1996).
-
Arnett FC, Shulman LE. Studies in familial systemic lupus erythematosus.
Medicine (Baltimore) 55: 313-322 (1976).
-
Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL. BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation.
J. Immunol. 178: 1523-1533 (2007).
*
-
Arnett HA, Viney JL. Considerations for the sensible use of rodent models of inflammatory disease in predicting efficacy of new biological therapeutics in the clinic.
Adv. Drug Deliv. Rev. 59: 1084-1092 (2007).
-
Arnold AP, Chen X. What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues?
Front. Neuroendocrinol. 30: 1-9 (2009).
-
Arnold KA, Eichelbaum M, Burk O. Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor.
Nucl. Recept. 2: 1 (2004).
*
-
Arnson Y, Amital H, Guiducci S, Matucci-Cerinic M, Valentini G, Barzilai O, Maya R, Shoenfeld Y. The role of infections in the immunopathogensis of systemic sclerosis-evidence from serological studies.
Ann. N. Y. Acad. Sci. 1173: 627-632 (2009).
*
-
Aronis A, Aharoni-Simon M, Madar Z, Tirosh O. Triacylglycerol-induced impairment in mitochondrial biogenesis and function in J774.2 and mouse peritoneal macrophage foam cells.
Arch. Biochem. Biophys. 492: 74-81 (2009).
*
-
Arpiainen S, Jarvenpaa SM, Manninen A, Viitala P, Lang MA, Pelkonen O, Hakkola J. Coactivator PGC-1alpha regulates the fasting inducible xenobiotic-metabolizing enzyme CYP2A5 in mouse primary hepatocytes.
Toxicol. Appl. Pharmacol. 232: 135-141 (2008).
*
-
Arranz E, Garrote JA. Immunology of celiac disease.
Gastroenterol. Hepatol. Feb 1 [Epub ahead of print] (2010).
-
Arredondo J, Chernyavsky AI, Jolkovsky DL, Webber RJ, Grando SA. SLURP-2: a novel cholinergic signaling peptide in human mucocutaneous epithelium.
J. Cell. Physiol. 208: 238-245 (2006).
*
-
Arredondo M, Jorquera D, Carrasco E, Albala C, Hertrampf E. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with iron status in persons with type 2 diabetes mellitus.
Am. J. Clin. Nutr. 86: 1347-1353 (2007).
*
-
Arrese M, Ananthanarayanan M. The bile salt export pump: molecular properties, function and regulation.
Pflugers Arch. 449: 123-131 (2004).
*
-
Arrese M, Miquel JF, Ananthanarayanan M. BetaKlotho: a new kid on the bile acid biosynthesis block.
Hepatology 43: 191-193 (2006).
*
-
Arriagada G, Paredes R, van Wijnen AJ, Lian JB, van Zundert B, Stein GS, Stein JL, Montecino M. 1alpha,25-Dihydroxy vitamin D(3) induces nuclear matrix association of the 1alpha,25-dihydroxy vitamin D(3) receptor in osteoblasts independently of its ability to bind DNA.
J. Cell Physiol. 222: 336-346 (2009).
-
Arrizabalaga P, Sole M, Iglesias C, Escaramís G, Ascaso C. Renal expression of ICAM-1 and VCAM-1 in ANCA-associated glomerulonephritis - are there differences among serologic subgroups?
Clin. Nephrol. 65: 79-86 (2006).
-
Arruda SF, Siqueira EM, de Valencia FF. Vitamin A deficiency increases hepcidin expression and oxidative stress in rat.
Nutrition 25: 472-478 (2009).
*
-
Arsenescu R, Bruno ME, Rogier EW, Stefka AT, McMahan AE, Wright TB, Nasser MS, de Villiers WJ, Kaetzel CS. Signature biomarkers in Crohn's disease: toward a molecular classification.
Mucosal Immunol. 1: 399-411 (2008).
-
Arshavsky YI. Why Alzheimer's disease starts with a memory impairment: neurophysiological insight.
J. Alzheimers Dis. Jan 7 [Epub ahead of print] (2010).
-
Artaza J, Norris K. Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells.
J. Endocrinol. 200: 207-221 (2009).
*
-
Artaza JN, Sirad F, Ferrini MG, Norris KC. 1,25(OH)(2)Vitamin D(3) inhibits cell proliferation by promoting cell cycle arrest without inducing apoptosis and modifies cell morphology of mesenchymal multipotent cells.
J. Steroid Biochem. Mol. Biol. Jan 8 [Epub ahead of print] (2010).
-
Arthur AT, Armati PJ, Bye C, Consortium SM, Heard RN, Stewart GJ, Pollard JD, Booth DR. Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission.
BMC Med. Genet. 9: 17 (2008).
*
-
Arthur MJ. Fibrogenesis. II. Metalloproteinases and their inhibitors in liver fibrosis.
Am. J. Physiol. Gastrointest. Liver Physiol. 279: G245-G249 (2000).
*
-
Artis D, Shapira S, Mason N, Speirs KM, Goldschmidt M, Caamano J, Liou HC, Hunter CA, Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation.
J. Immunol. 169: 4481-4487 (2002).
*
-
Artis DR, Lin JJ, Zhang C, Wang W, Mehra U, Perreault M, Erbe D, Krupka HI, England BP, Arnold J, Plotnikov AN, Marimuthu A, Nguyen H, Will S, Signaevsky M, Kral J, Cantwell J, Settachatgull C, Yan DS, Fong D, Oh A, Shi S, Womack P, Powell B, et al. Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent.
Proc. Natl. Acad. Sci. U.S.A. 106: 262-267 (2009).
*
-
Arukwe A, Nordbo B. Hepatic biotransformation responses in Atlantic salmon exposed to retinoic acids and 3,3',4,4'-tetrachlorobiphenyl (PCB congener 77).
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 147: 470-482 (2008).
*
-
Arumugakani G, Wood PM, Carter CR. Frequency of Treg cells is reduced in CVID patients with autoimmunity and splenomegaly and is associated with expanded CD21(lo) B lymphocytes.
J. Clin. Immunol. Dec 9 [Epub ahead of print] (2009).
*
-
Aruna BV, Sela M, Mozes E. Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells.
Proc. Natl. Acad. Sci. U.S.A. 102: 10285-10290 (2005).
*
-
Arundel C, Lewis JH. Drug-induced liver disease in 2006.
Curr. Opin. Gastroenterol. 23: 244-254 (2007).
-
Arya R, Mallik M, Lakhotia SC. Heat shock genes - integrating cell survival and death.
J. Biosci. 32: 595-610 (2007).
*
-
Arzuaga X, Reiterer G, Majkova Z, Kilgore MW, Toborek M, Hennig B. PPARalpha ligands reduce PCB-induced endothelial activation: possible interactions in inflammation and atherosclerosis.
Cardiovasc. Toxicol. 7: 264-272 (2007).
*
-
Arzuaga X, Ren N, Stromberg A, Black EP, Arsenescu V, Cassis LA, Majkova Z, Toborek M, Hennig B. Induction of gene pattern changes associated with dysfunctional lipid metabolism induced by dietary fat and exposure to a persistent organic pollutant.
Toxicol. Lett. 189: 96-101 (2009).
*
-
Asahina K, Tsai SY, Li P, Ishii M, Maxson RE Jr, Sucov HM, Tsukamoto H. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development.
Hepatology 49: 998-1011 (2009).
-
Asai Y, Makimura Y, Ogawa T. Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide.
J. Med. Microbiol. 56: 459-465 (2007).
*
-
Asaka JI, Terada T, Ogasawara K, Katsura T, Inui KI. Characterization of the basal promoter element of human organic cation transporter 2 (hOCT2) gene.
J. Pharmacol. Exp. Ther. 321: 684-689 (2007).
*
-
Asaka JI, Terada T, Okuda M, Katsura T, Inui KI. Androgen receptor is responsible for rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3.
Pharm. Res. 23: 697-704 (2006).
*
-
Asakura H, Sugimura K, Funakoshi K. Molecular pathoimmunology of ulcerative colitis.
Nippon Rinsho 54: 1170-1175 (1996).
-
Asano Y, Ihn H, Jinnin M, Mimura Y, Tamaki K. Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma.
J. Invest. Dermatol. 126: 1761-1769 (2006).
*
-
Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K. Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts.
J. Immunol. 175: 7708-7718 (2005).
*
-
Asano Y, Iimuro Y, Son G, Hirano T, Fujimoto J. Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver.
Hepatol. Res. 37: 1080-1094 (2007).
*
-
Asghar A, Gorski JC, Haehner-Daniels B, Hall SD. Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.
Drug Metab. Dispos. 30: 20-26 (2002).
*
-
Ashikov A, Routier F, Fuhlrott J, Helmus Y, Wild MK, Gerardy-Schahn R, Bakker H. The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine.
J. Biol. Chem. 280: 27230-27235 (2005).
*
-
Ashino T, Arima Y, Shioda S, Iwakura Y, Numazawa S, Yoshida T. Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver.
Eur. J. Pharmacol. 558: 199-207 (2007).
*
-
Ashkar AA, Yao XD, Gill N, Sajic D, Patrick AJ, Rosenthal KL. Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA.
J. Infect. Dis. 190: 1841-1849 (2004).
*
-
Ashman RF, Schaffer FM, Kemp JD, Yokoyama WM, Zhu ZB, Cooper MD, Volanakis JE. Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency.
J. Clin. Immunol. 12: 406-414 (1992).
-
Ashwell JD, Lu FW, Vacchio MS. Glucocorticoids in T cell development and function.
Annu. Rev. Immunol. 18: 309-345 (2000).
*
-
Ashwood P, Harvey R, Verjee T, Wolstencroft R, Thompson RP, Powell JJ. Functional interactions between mucosal IL-1, IL-ra and TGF-beta 1 in ulcerative colitis.
Inflamm. Res. 53: 53-59 (2004).
*
-
Askar E, Bregadze R, Mertens J, Schweyer S, Rosenberger A, Ramadori G, Mihm S. TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C.
J. Med. Virol. 81: 1204-1211 (2009).
*
-
Asling B, Jirholt J, Hammond P, Knutsson M, Walentinsson A, Davidson G, Agreus L, Lehmann A, Lagerstrom-Fermer M. Collagen type III alpha I (COL3A1) is a gastro-oesophageal reflux disease (GORD) susceptibility gene and a male risk factor for hiatus hernia (HH).
Gut 58: 1063-1069 (2009).
*
-
Asnani S, Theuma P, Fonseca VA. PPARgamma agonists and vascular risk factors: potential effects on cardiovascular disease.
Metab. Syndr. Relat. Disord. 1: 23-32 (2003).
-
Aspinall R. T cell development, ageing and interleukin-7.
Mech. Ageing Dev. 127: 572-578 (2006).
-
Asquith DL, McInnes IB. Emerging cytokine targets in rheumatoid arthritis.
Curr. Opin. Rheumatol. 19: 246-251 (2007).
*
-
Asquith DL, Miller AM, Hueber AJ, McKinnon HJ, Sattar N, Graham GJ, McInnes IB. Liver X receptor agonism promotes articular inflammation in murine collagen-induced arthritis.
Arthritis Rheum. 60: 2655-2665 (2009).
*
-
Assassi S, Tan FK. Genetics of scleroderma: update on single nucleotide polymorphism analysis and microarrays.
Curr. Opin. Rheumatol. 17: 761-767 (2005).
-
Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice.
J. Biol. Chem. 279: 22250-22257 (2004).
*
-
Assenat E, Gerbal-Chaloin S, Larrey D, Saric J, Fabre JM, Maurel P, Vilarem MJ, Pascussi JM. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance.
Hepatology 40: 951-960 (2004).
*
-
Assi K, Mills J, Owen D, Ong C, St Arnaud R, Dedhar S, Salh B. Integrin-linked kinase regulates cell proliferation and tumor growth in murine colitis-associated carcinogenesis.
Gut 57: 931-940 (2008).
-
Assi LK, Wong SH, Ludwig A, Raza K, Gordon C, Salmon M, Lord JM, Scheel-Toellner D. Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint.
Arthritis Rheum. 56: 1776-1786 (2007).
*
-
Assuncao-Miranda I, Bozza MT, Da Poian AT. Pro-inflammatory response resulting from sindbis virus infection of human macrophages: implications for the pathogenesis of viral arthritis.
J. Med. Virol. 82: 164-174 (2009).
*
-
Astapova I, Lee LJ, Morales C, Tauber S, Bilban M, Hollenberg AN. The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo.
Proc. Natl. Acad. Sci. U.S.A. 105: 19544-19549 (2008).
*
-
Asumalahti K, Veal C, Laitinen T, Suomela S, Allen M, Elomaa O, Moser M, de Cid R, Ripatti S, Vorechovsky I, Marcusson JA, Nakagawa H, Lazaro C, Estivill X, Capon F, Novelli G, Saarialho-Kere U, Barker J, Trembath R, Kere J; Psoriasis Consortium. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus.
Hum. Mol. Genet. 11: 589-597 (2002).
*
-
Atalay A, Yildiz-Demirtepe S, Tatlipinar S, Sanli-Erdogan B, Cobankara V, Yildirim C, Bagci H, Atalay EO. HLA-B51 gene and its expression in association with Behcet's disease in Denizli province of Turkey.
Mol. Biol. Rep. 35: 345-349 (2008).
*
-
Atalay C, Deliloglu Gurhan I, Irkkan C, Gunduz U. Multidrug resistance in locally advanced breast cancer.
Tumour Biol. 27: 309-318 (2006).
-
Atar D, Dyrberg T, Michelsen B, Karlsen A, Kofod H, Mølvig J, Lernmark A. Site-specific antibodies distinguish single amino acid substitutions in position 57 in HLA-DQ beta-chain alleles associated with insulin-dependent diabetes.
J. Immunol. 143: 533-538 (1989).
-
Ates O, Dalyan L, Hatemi G, Hamuryudan V, Topal-Sarikaya A. Genetic susceptibility to Behcet's syndrome is associated with NRAMP1 (SLC11A1) polymorphism in Turkish patients.
Rheumatol. Int. 29: 787-791 (2009).
*
-
Ates O, Musellim B, Ongen G, Topal-Sarikaya A. NRAMP1 (SLC11A1): a plausible candidate gene for systemic sclerosis (SSc) with interstitial lung involvement.
J. Clin. Immunol. 28: 73-77 (2008).
*
-
Athyros VG, Kakafika AI, Tziomalos K, Karagiannis A, Mikhailidis DP. Antisense technology for the prevention or the treatment of cardiovascular disease: the next blockbuster?
Expert Opin. Investig. Drugs 17: 969-972 (2008).
-
Atkins D, Breuckmann A, Schmahl GE, Binner P, Ferrone S, Krummenauer F, Storkel S, Seliger B. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma.
Int. J. Cancer 109: 265-273 (2004).
*
-
Atkins KB, Troen BR. Regulation of cathepsin D gene expression in HL-60 cells by retinoic acid and calcitriol.
Cell Growth Differ. 6: 871-877 (1995).
-
Atkinson EM. American society of gene therapy - third annual meeting.
IDrugs 3: 1009-1011 (2000).
-
Atkinson TJ. Toll-like receptors, transduction-effector pathways, and disease diversity: evidence of an immunobiological paradigm explaining all human illness?
Int. Rev. Immunol. 27: 255-281 (2008).
-
Atreya I, Atreya R, Neurath MF. NF-kappaB in inflammatory bowel disease.
J. Intern. Med. 263: 591-596 (2008).
*
-
Atreya R, Neurath MF. Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer.
Clin. Rev. Allergy Immunol. 28: 187-196 (2005).
-
Atta HM, Al-Hendy A, Salama SA, Shaker OG, Hammam OA. Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation.
Liver Int. 29: 1022-1030 (2009).
-
Attakpa E, Hichami A, Simonin AM, Sanson EG, Dramane KL, Khan NA. Docosahexaenoic acid modulates the expression of T-bet and GATA-3 transcription factors, independently of PPARalpha, through suppression of MAP kinase activation.
Biochimie 91: 1359-1365 (2009).
-
Attene-Ramos MS, Nava GM, Muellner MG, Wagner ED, Plewa MJ, Gaskins HR. DNA damage and toxicogenomic analyses of hydrogen sulfide in human intestinal epithelial FHs 74 Int cells.
Environ. Mol. Mutagen. Jan 29 [Epub ahead of print] (2010).
-
Atug O, Tahan V, Eren F, Tiftikci A, Imeryuz N, Hamzaoglu HO, Tozun N. Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease.
J. Gastrointestin. Liver Dis. 17: 433-437 (2008).
*
-
Atzeni F, Boiardi L, Casali B, Farnetti E, Sarzi-Puttini P, Pipitone N, Olivieri I, Cantini F, Salvi F, La Corte R, Triolo G, Filippini D, Paolazzi G, Salvarani C. Lack of association of the 463 G/A myeloperoxidase promoter polymorphism with Behcet's disease in Italian patients.
Rheumatology (Oxford) 46: 1547-1550 (2007).
*
-
Aubareda A, Mulero MC, Perez-Riba M. Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells.
Cell. Signal. 18: 1430-1438 (2006).
*
-
Aubourg P. X-linked adrenoleukodystrophy.
Ann. Endocrinol. (Paris) 68: 403-411 (2007).
-
Aubry EM, Odermatt A. Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities.
Endocrinology 150: 2700-2708 (2009).
*
-
Auer-Grumbach M, Olschewski A, Papic L, Kremer H, McEntagart ME, Uhrig S, Fischer C, Frohlich E, Balint Z, Tang B, Strohmaier H, Lochmuller H, Schlotter-Weigel B, Senderek J, Krebs A, Dick KJ, Petty R, Longman C, Anderson NE, Padberg GW, et al. Alterations in the ankyrin domain of TRPV4 cause congenital distal SMA, scapuloperoneal SMA and HMSN2C.
Nat. Genet. Dec 27 [Epub ahead of print] (2009).
*
-
Auerbach SS, Dekeyser JG, Stoner MA, Omiecinski CJ. CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics.
Drug Metab. Dispos. 35: 428-439 (2007).
*
-
Auerbach SS, Stoner MA, Su S, Omiecinski CJ. Retinoid X receptor-dependent transactivation by a naturally occurring structural variant of human CAR (NR1I3).
Mol. Pharmacol. 68: 1239-1253 (2005).
*
-
Augello A, Tasso R, Negrini SM, Amateis A, Indiveri F, Cancedda R, Pennesi G. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway.
Eur. J. Immunol. 35: 1482-1490 (2005).
*
-
Augello A, Tasso R, Negrini SM, Cancedda R, Pennesi G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis.
Arthritis Rheum. 56: 1175-1186 (2007).
*
-
Augereau P, Badia E, Carascossa S, Castet A, Fritsch S, Harmand PO, Jalaguier S, Cavailles V. The nuclear receptor transcriptional coregulator RIP140.
Nucl. Recept. Signal. 4: e024 (2006).
*
-
Augoustides-Savvopoulou P, Luka Z, Karyda S, Stabler SP, Allen RH, Patsiaoura K, Wagner C, Mudd SH. Glycine N-methyltransferase deficiency: a new patient with a novel mutation.
J. Inherit. Metab. Dis. 26: 745-759 (2003).
*
-
Augustin MT, Kokkonen J, Karttunen TJ. Duodenal cytotoxic lymphocytes in cow's milk protein sensitive enteropathy and coeliac disease.
Scand. J. Gastroenterol. 40: 1398-1406 (2005).
*
-
Aulisa L, Papaleo P, Pola E, Angelini F, Aulisa AG, Tamburrelli FC, Pola P, Logroscino CA. Association between IL-6 and MMP-3 gene polymorphisms and adolescent idiopathic scoliosis: a case-control study.
Spine 32: 2700-2702 (2007).
-
Aune TM, Maas K, Moore JH, Olsen NJ. Gene expression profiles in human autoimmune disease.
Curr. Pharm. Des. 9: 1905-1917 (2003).
-
Aune TM, Maas K, Parker J, Moore JH, Olsen NJ. Profiles of gene expression in human autoimmune disease.
Cell. Biochem. Biophys. 40: 81-96 (2004).
-
Aune TM, Parker JS, Maas K, Liu Z, Olsen NJ, Moore JH. Co-localization of differentially expressed genes and shared susceptibility loci in human autoimmunity.
Genet. Epidemiol. 27: 162-172 (2004).
*
-
Aust DE, Haase M, Dobryden L, Markwarth A, Lohrs U, Wittekind C, Baretton GB, Tannapfel A. Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma.
Int. J. Cancer 115: 673-677 (2005).
*
-
Aust S, Brucker B, Graf J, Klimpfinger M, Thalhammer T. Melatonin modulates acid/base transport in human pancreatic carcinoma cells.
Cell. Physiol. Biochem. 18: 91-102 (2006).
*
-
Austin AS, Haas KM, Naugler SM, Bajer AA, Garcia-Tapia D, Estes DM. Identification and characterization of a novel regulatory factor: IgA-inducing protein.
J. Immunol. 171: 1336-1342 (2003).
*
-
Autenrieth IB, Bucheler N, Bohn E, Heinze G, Horak I. Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation.
Gut 41: 793-800 (1997).
*
-
Auth MK, Woitaschek D, Beste M, Schreiter T, Kim HS, Oppermann E, Joplin RE, Baumann U, Hilgard P, Nadalin S, Markus BH, Blaheta RA. Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells.
Liver Transpl. 11: 410-419 (2005).
*
-
Autschbach F, Braunstein J, Helmke B, Zuna I, Schurmann G, Niemir ZI, Wallich R, Otto HF, Meuer SC. In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease.
Am. J. Pathol. 153: 121-130 (1998).
*
-
Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, De Angelis MH, Jackson I, Kioussis D, et al. The European dimension for the mouse genome mutagenesis program.
Nat. Genet. 36: 925-927 (2004).
*
-
Auwerx J, Schoonjans K, Fruchart JC, Staels B. Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects.
J. Atheroscler. Thromb. 3: 81-89 (1996).
-
Avallone R, Demers A, Rodrigue-Way A, Bujold K, Harb D, Anghel S, Wahli W, Marleau S, Ong H, Tremblay A. A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor upregulates ABC sterol transporters and cholesterol efflux in macrophages through a PPARgamma-dependent pathway.
Mol. Endocrinol. 20: 3165-3178 (2006).
*
-
Avasarala JR, Chittur SV, George AD, Tine JA. Microarray analysis in B cells among siblings with/without MS - role for transcription factor TCF2.
BMC Med. Genomics 1: 2 (2008).
*
-
Avbelj M, Tahirovic H, Debeljak M, Kusekova M, Toromanovic A, Krzisnik C, Battelino T. High prevalence of thyroid peroxidase gene mutations in patients with thyroid dyshormonogenesis.
Eur. J. Endocrinol. 156: 511-519 (2007).
*
-
Averdam A, Kuhl H, Sontag M, Becker T, Hughes AL, Reinhardt R, Walter L. Genomics and diversity of the common marmoset monkey NK complex.
J. Immunol. 178: 7151-7161 (2007).
*
-
Aversa A, Caprio M, Rosano GM, Spera G. Endothelial effects of drugs designed to treat erectile dysfunction.
Curr. Pharm. Des. 14: 3768-3778 (2009).
-
Avila E, Diaz L, Barrera D, Halhali A, Mendez I, Gonzalez L, Zuegel U, Steinmeyer A, Larrea F. Regulation of vitamin D hydroxylases gene expression by 1,25-dihydroxyvitamin D(3) and cyclic AMP in cultured human syncytiotrophoblasts.
J. Steroid Biochem. Mol. Biol. 103: 90-96 (2007).
-
Avila MA, Berasain C, Torres L, Martin-Duce A, Corrales FJ, Yang H, Prieto J, Lu SC, Caballeria J, Rodes J, Mato JM. Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma.
J. Hepatol. 33: 907-914 (2000).
*
-
Avila MA, Garcia-Trevijano ER, Martinez-Chantar ML, Latasa MU, Perez-Mato I, Martinez-Cruz LA, del Pino MM, Corrales FJ, Mato JM. S-Adenosylmethionine revisited: its essential role in the regulation of liver function.
Alcohol 27: 163-167 (2002).
*
-
Awane M, Andres PG, Li DJ, Reinecker HC. NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cells.
J. Immunol. 162: 5337-5344 (1999).
*
-
Awara WM, El-Sisi AE, El-Refaei M, El-Naa MM, El-Desoky K. Insulinotropic and anti-inflammatory effects of rosiglitazone in experimental autoimmune diabetes.
Rev. Diabet. Stud. 2: 146-156 (2005).
*
-
Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M, Weiner HL. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells.
Nat. Immunol. 8: 1380-1389 (2007).
*
-
Awasthi A, Riol-Blanco L, Jager A, Korn T, Pot C, Galileos G, Bettelli E, Kuchroo VK, Oukka M. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells.
J. Immunol. 182: 5904-5908 (2009).
-
Axmann R, Bohm C, Kronke G, Zwerina J, Smolen J, Schett G. Inhibition of interleukin-6 receptor directly blocks osteoclast formation in vitro and in vivo.
Arthritis Rheum. 60: 2747-2756 (2009).
*
-
Ayaori M, Sawada S, Yonemura A, Iwamoto N, Ogura M, Tanaka N, Nakaya K, Kusuhara M, Nakamura H, Ohsuzu F. Glucocorticoid receptor regulates ATP-binding cassette transporter-A1 expression and apolipoprotein-mediated cholesterol efflux from macrophages.
Arterioscler. Thromb. Vasc. Biol. 26: 163-168 (2006).
*
-
Ayensu WK, Tchounwou PB. Microarray analysis of mercury-induced changes in gene expression in human liver carcinoma (HepG2) cells: importance in immune responses.
Int. J. Environ. Res. Public Health 3: 141-173 (2006).
-
Ayilavarapu S, Kantarci A, Fredman G, Turkoglu O, Omori K, Liu H, Iwata T, Yagi M, Hasturk H, Van Dyke TE. Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils.
J. Immunol. Jan 6 [Epub ahead of print] (2010).
-
Ayroles JF, Carbone MA, Stone EA, Jordan KW, Lyman RF, Magwire MM, Rollmann SM, Duncan LH, Lawrence F, Anholt RR, Mackay TF. Systems genetics of complex traits in Drosophila melanogaster.
Nat. Genet. 41: 299-307 (2009).
*
-
Azarpira N, Aghdaie MH, Behzad-Behbahanie A, Geramizadeh B, Behzadi S, Malekhoseinie SA, Raisjalal GH, Rahsaz M, Pourgholami A, Sagheb F. Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation.
Exp. Clin. Transplant. 4: 416-419 (2006).
-
Azeredo EL, Neves-Souza PC, Alvarenga AR, Reis SR, Torrentes-Carvalho A, Zagne SM, Nogueira RM, Oliveira-Pinto LM, Kubelka CF. Differential regulation of Toll-like receptor-2, Toll-like receptor-4, CD16 and human leucocyte antigen-DR on peripheral blood monocytes during mild and severe dengue fever.
Immunology Jan 27 [Epub ahead of print] (2010).
*
-
Azim K, McManus R, Brophy K, Ryan A, Kelleher D, Reynolds JV. Genetic polymorphisms and the risk of infection following esophagectomy: positive association with TNF-alpha gene -308 genotype.
Ann. Surg. 246: 122-128 (2007).
*
-
Aziz A, Xiao CW, Cockell KA, Sarwar Gilani G, Cruz-Hernandez C, Nimal Ratnayake WM. Impact of dietary protein on lipid metabolism in hamsters is source-dependent and associated with changes in hepatic gene expression.
Br. J. Nutr. 100: 503-511 (2008).
*
-
Azmy IA, Balasubramanian SP, Wilson AG, Stephenson TJ, Cox A, Brown NJ, Reed MW. Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity.
Breast Cancer Res. 6: R395-R400 (2004).
*
-
Azuma T, Zhu G, Xu H, Rietz AC, Drake CG, Matteson EL, Chen L. Potential role of decoy B7-H4 in the pathogenesis of rheumatoid arthritis: a mouse model informed by clinical data.
PLoS Med. 6: e1000166 (2009).
*
-
Azuz-Lieberman N, Markel G, Mizrahi S, Gazit R, Hanna J, Achdout H, Gruda R, Katz G, Arnon TI, Battat S, Zamir E, Adawi M, Mader R, Mandelboim O. The involvement of NK cells in ankylosing spondylitis.
Int. Immunol. 17: 837-845 (2005).
*
-
Azzi A, Gysin R, Kempna P, Munteanu A, Negis Y, Villacorta L, Visarius T, Zingg JM. Vitamin E mediates cell signaling and regulation of gene expression.
Ann. N. Y. Acad. Sci. 1031: 86-95 (2004).
*
-
Azzi A, Gysin R, Kempna P, Munteanu A, Villacorta L, Visarius T, Zingg JM. Regulation of gene expression by alpha-tocopherol.
Biol. Chem. 385: 585-591 (2004).
-
Baader M, Gnerre C, Stegeman JJ, Meyer UA. Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit.
J. Biol. Chem. 277: 15647-15653 (2002).
*
-
Baadsgaard O, Fisher G, Voorhees JJ, Cooper KD. The role of immune system in the pathogenesis of psoriasis.
J. Invest. Dermatol. 95: 32S-34S (1990).
*
-
Baba MI, Kaul D, Grover A. Importance of blood cellular genomic profile in coronary heart disease.
J. Biomed. Sci. 13: 17-26 (2006).
*
-
Baba N, Kobashi H, Yamamoto K, Terada R, Suzuki T, Hakoda T, Okano N, Shimada N, Fujioka S, Iwasaki Y, Shiratori Y. Gene expression profiling in biliary epithelial cells of primary biliary cirrhosis using laser capture microdissection and cDNA microarray.
Transl. Res. 148: 103-113 (2006).
*
-
Baba T, Ishizu A, Ikeda H, Miyatake Y, Tsuji T, Suzuki A, Tomaru U, Yoshiki T. Chronic graft-versus-host disease-like autoimmune disorders spontaneously occurred in rats with neonatal thymus atrophy.
Eur. J. Immunol. 35: 1731-1740 (2005).
*
-
Babcock AA, Wirenfeldt M, Holm T, Nielsen HH, Dissing-Olesen L, Toft-Hansen H, Millward JM, Landmann R, Rivest S, Finsen B, Owens T. Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation.
J. Neurosci. 26: 12826-12837 (2006).
-
Babcock TA, Carlin JM. Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells.
Cytokine 12: 588-594 (2000).
-
Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Groene HJ, Schaefer L. Biglycan, a danger signal that activates the NLRP3 inflammasome via Toll-like and P2X receptors.
J. Biol. Chem. 284: 24035-24048 (2009).
*
-
Babidge W, Millard S, Roediger W. Sulfides impair short chain fatty acid beta-oxidation at acyl-CoA dehydrogenase level in colonocytes: implications for ulcerative colitis.
Mol. Cell. Biochem. 181: 117-124 (1998).
-
Babu D, Lee JS, Park SY, Thapa D, Choi MK, Kim AR, Park YJ, Kim JA. Involvement of NF-kappaB in the inhibitory actions of Platycarya strobilacea on the TNF-alpha-induced monocyte adhesion to colon epithelial cells and chemokine expression.
Arch. Pharm. Res. 31: 727-735 (2008).
*
-
Babu D, Thapa D, Lee JS, Park SY, Kim AR, Kim YH, Yang HC, Kim JA. Inhibitory effects of an aqueous extract of Cornus kousa Burg. leaves on TNF-alpha-induced chemokine expression and monocyte adhesion to human colonic epithelial cells.
Arch. Pharm. Res. 32: 91-98 (2009).
*
-
Babu MM. Computational approaches to study transcriptional regulation.
Biochem. Soc. Trans. 36: 758-765 (2008).
*
-
Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence.
J. Immunol. 176: 3248-3256 (2006).
*
-
Babyatsky MW, Rossiter G, Podolsky DK. Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease.
Gastroenterology 110: 975-984 (1996).
*
-
Bach JP, Rinn B, Meyer B, Dodel R, Bacher M. Role of MIF in inflammation and tumorigenesis.
Oncology 75: 127-133 (2008).
*
-
Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells.
Gastroenterology 128: 907-921 (2005).
*
-
Bacher S, Schmitz ML. The NF-kappa B pathway as a potential target for autoimmune disease therapy.
Curr. Pharm. Des. 10: 2827-2837 (2004).
-
Bachleda P, Vrzal R, Pivnicka J, Cvek B, Dvorak Z. Examination of zolpidem effects on AhR and PXR dependent expression of drug-metabolizing cytochromes P450 in primary cultures of human hepatocytes.
Toxicol. Lett. 191: 74-78 (2009).
-
Bachmann MP, Bartsch H, Gross JK, Maier SM, Gross TF, Workman JL, James JA, Farris AD, Jung B, Franke C, Conrad K, Schmitz M, Buttner C, Buyon JP, Semsei I, Harley JB, Rieber EP. Autoimmunity as a result of escape from RNA surveillance.
J. Immunol. 177: 1698-1707 (2006).
*
-
Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL,Katkuri S, Dubois RN. 15-Hydroxyprostaglandin dehydrogenase is downregulated in colorectal cancer.
J. Biol. Chem. 280: 3217-3223 (2005).
*
-
Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM. Interaction of methotrexate with OATP1A2 and its genetic variants.
J. Pharmacol. Exp. Ther. 318: 521-529 (2006).
*
-
Badman MK, Koester A, Flier JS, Kharitonenkov A, Maratos-Flier E. Fibroblast growth factor 21-deficient mice demonstrate impaired adaptation to ketosis.
Endocrinology 150: 4931-4940 (2009).
*
-
Badot V, Galant C, Nzeusseu Toukap A, Theate I, Maudoux AL, Van den Eynde BJ, Durez P, Houssiau FA, Lauwerys BR. Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis.
Arthritis Res. Ther. 11: R57 (2009).
*
-
Badou A, Saoudi A, Dietrich G, Druet E, Druet P, Pelletier L. Mercuric chloride-induced autoimmunity.
Curr. Protoc. Immunol. Chapter 15: Unit 15.15 (2001).
-
Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis.
Clin. Exp. Immunol. 148: 410-418 (2007).
*
-
Bae EH, Lee J, Ma SK, Kim IJ, Frokiaer J, Nielsen S, Kim SY, Kim SW. alpha-Lipoic acid prevents cisplatin-induced acute kidney injury in rats.
Nephrol. Dial. Transplant. 24: 2692-2700 (2009).
-
Bae JS, Gutierrez S, Narla R, Pratap J, Devados R, van Wijnen AJ, Stein JL, Stein GS, Lian JB, Javed A. Reconstitution of Runx2/Cbfa1-null cells identifies a requirement for BMP2 signaling through a Runx2 functional domain during osteoblast differentiation.
J. Cell. Biochem. 100: 434-449 (2007).
-
Bae SC, Choi JK. Tumor suppressor activity of RUNX3.
Oncogene 23: 4336-4340 (2004).
*
-
Bae Y, Kemper JK, Kemper B. Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP).
DNA Cell Biol. 23: 81-91 (2004).
-
Bae YS, Lee JH, Choi SH, Kim S, Almazan F, Witztum JL, Miller YI. Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein. Toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2.
Circ. Res. 104: 210-218 (2009).
*
-
Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, Espe KJ, Balasubramanian S, Hughes KM, Chan JP, Begovich A, Chang SY, Gregersen PK, Behrens TW. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation.
Genes Immun. 5: 347-353 (2004).
*
-
Baechler EC, Batliwalla FM, Reed AM, Peterson EJ, Gaffney PM, Moser KL, Gregersen PK, Behrens TW. Gene expression profiling in human autoimmunity.
Immunol. Rev. 210: 120-137 (2006).
*
-
Baechler EC, Bauer JW, Slattery CA, Ortmann WA, Espe KJ, Novitzke J, Ytterberg SR, Gregersen PK, Behrens TW, Reed AM. An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity.
Mol. Med. 13: 59-68 (2007).
*
-
Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, Yamaguchi K, Mishina Y, Martin DW, Shoieb A, McEntee MF, Eling TE. Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia.
Gastroenterology 131: 1553-1560 (2006).
*
-
Baek SJ, Wilson LC, Lee CH, Eling TE. Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene.
J. Pharmacol. Exp. Ther. 301: 1126-1131 (2002).
*
-
Baek WY, Lee MA, Jung JW, Kim SY, Akiyama H, de Crombrugghe B, Kim JE. Positive regulation of adult bone formation by osteoblast-specific transcription factor Osterix.
J. Bone Miner. Res. 24: 1055-1065 (2009).
*
-
Baerwald CG, Panayi GS, Lanchbury JS. Corticotropin releasing hormone promoter region polymorphisms in rheumatoid arthritis.
J. Rheumatol. 24: 215-216 (1997).
-
Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, Moore DD. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements.
Mol. Cell Biol. 14: 1544-1552 (1994).
*
-
Baeten D, Steenbakkers PG, Rijnders AM, Boots AM, Veys EM, De Keyser F. Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker.
Arthritis Rheum. 50: 444-451 (2004).
*
-
Baetz A, Frey M, Heeg K, Dalpke AH. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells.
J. Biol. Chem. 279: 54708-54715 (2004).
*
-
Baev DV, Caielli S, Ronchi F, Coccia M, Facciotti F, Nichols KE, Falcone M. Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice.
J. Immunol. 181: 869-877 (2008).
*
-
Baganz NL, Horton RE, Calderon AS, Owens WA, Munn JL, Watts LT, Koldzic-Zivanovic N, Jeske NA, Koek W, Toney GM, Daws LC. Organic cation transporter 3: keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice.
Proc. Natl. Acad. Sci. U.S.A. 105: 18976-18981 (2008).
*
-
Bagdanoff JT, Donoviel MS, Nouraldeen A, Tarver J, Fu Q, Carlsen M, Jessop TC, Zhang H, Hazelwood J, Nguyen H, Baugh SD, Gardyan M, Terranova KM, Barbosa J, Yan J, Bednarz M, Layek S, Taylor J, Digeorge-Foushee AM, Gopinathan S, Bruce D, Smith T, et al. Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders.
J. Med. Chem. 52: 3941-3953 (2009).
*
-
Bagga D, Wang L, Farias-Eisner R, Glaspy JA, Reddy ST. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion.
Proc. Natl. Acad. Sci. U.S.A. 100: 1751-1756 (2003).
*
-
Baggio B, Musacchio E, Priante G. Polyunsaturated fatty acids and renal fibrosis: pathophysiologic link and potential clinical implications.
J. Nephrol. 18: 362-367 (2005).
-
Bagnall RD, Roberts RG, Mirza MM, Torigoe T, Prescott NJ, Mathew CG. Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation.
Eur. J. Hum. Genet. 16: 619-625 (2008).
*
-
Bagnoli S, Putignano AL, Melean G, Baglioni S, Sestini R, Milla M, d'Albasio G, Genuardi M, Pacini F, Trallori G, Papi L. Susceptibility to refractory ulcerative colitis is associated with polymorphism in the hMLH1 mismatch repair gene.
Inflamm. Bowel Dis. 10: 705-708 (2004).
*
-
Bagnyukova TV, Tryndyak VP, Muskhelishvili L, Ross SA, Beland FA, Pogribny IP. Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats.
Cell Cycle 7: 3202-3210 (2008).
*
-
Baharvand H, Hashemi SM, Shahsavani M. Differentiation of human embryonic stem cells into functional hepatocyte-like cells in a serum-free adherent culture condition.
Differentiation 76: 465-477 (2008).
-
Bahn A, Ebbinghaus C, Ebbinghaus D, Ponimaskin EG, Fuzesi L, Burckhardt G, Hagos Y. Expression studies and functional characterization of renal human organic anion transporter 1 isoforms.
Drug Metab. Dispos. 32: 424-430 (2004).
*
-
Bahn A, Hagos Y, Rudolph T, Burckhardt G. Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport.
Biochimie 86: 133-136 (2004).
-
Bahri R, Naji A, Menier C, Charpentier B, Carosella ED, Rouas-Freiss N, Durrbach A. Dendritic cells secrete the immunosuppressive HLA-G molecule upon CTLA4-Ig treatment: implication in human renal transplant acceptance.
J. Immunol. 183: 7054-7062 (2009).
-
Bai A, Hu P, Chen J, Song X, Chen W, Peng W, Zeng Z, Gao X. Blockade of STAT3 by antisense oligonucleotide in TNBS-induced murine colitis.
Int. J. Colorectal Dis. 22: 625-635 (2007).
*
-
Bai DS, Dai Z, Zhou J, Liu YK, Qiu SJ, Tan CJ, Shi YH, Huang C, Wang Z, He YF, Fan J. Capn4 overexpression underlies tumor invasion and metastasis after liver transplantation for hepatocellular carcinoma.
Hepatology 49: 460-470 (2009).
*
-
Bai H, Cheng J, Gao X, Joyee AG, Fan Y, Wang S, Jiao L, Yao Z, Yang X. IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function.
J. Immunol. 183: 5886-5895 (2009).
*
-
Bai J, Odin JA. Apoptosis and the liver: relation to autoimmunity and related conditions.
Autoimmun. Rev. 2: 36-42 (2003).
*
-
Bai J, Wang S, Liu J, Ye Z, Yu X, Xi Q, Hu D, Su S. Characterization of circulating CD4(+)CD25(high) regulatory T cells in men with chronic prostatitis/chronic pelvic pain syndrome.
Urology Oct 1 [Epub ahead of print] (2009).
-
Bai L, Kao JY, Law DJ, Merchant JL. Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection.
Gastroenterology 131: 841-852 (2006).
*
-
Bai L, Zimmer S, Rickes O, Rohleder N, Holthues H, Engel L, Leube R, Spessert R. Daily oscillation of gene expression in the retina is phase-advanced with respect to the pineal gland.
Brain Res. 1203: 89-96 (2008).
-
Bai P, Houten SM, Huber A, Schreiber V, Watanabe M, Kiss B, de Murcia G, Auwerx J, Menissier-de Murcia J. PARP-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the RXR/PPARgamma heterodimer.
J. Biol. Chem. 282: 37738-37746 (2007).
*
-
Bai S, Kitaura H, Zhao H, Chen J, Muller JM, Schule R, Darnay B, Novack DV, Ross FP, Teitelbaum SL. FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner.
J. Clin. Invest. 115: 2742-2751 (2005).
*
-
Bai S, Nasser MW, Wang B, Hsu SH, Datta J, Kutay H, Yadav A, Nuovo G, Kumar P, Ghoshal K. MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to Sorafenib.
J. Biol. Chem. 284: 32015-32027 (2009).
*
-
Bai S, Stepkowski SM, Kahan BD, Brunner LJ. Metabolic interaction between cyclosporine and sirolimus.
Transplantation 77: 1507-1512 (2004).
-
Bai S, Wang H, Shen J, Zhou R, Bushinsky DA, Favus MJ. Elevated vitamin D receptor levels in genetic hypercalciuric stone-forming rats are associated with down-regulation of Snail.
J. Bone Miner. Res. Nov 24 [Epub ahead of print] (2009).
*
-
Bai XP, Li HL, Yang WY, Xiao JZ, Wang B, Du RQ, Lou DJ. Effects of fenofibrate on gene expression of carnitine palmitoyltransferase 1 in liver and skeletal muscle and its influence on insulin sensitivity.
Zhonghua Yi Xue Za Zhi 88: 268-270 (2008).
-
Bai Y, Onuma H, Bai X, Medvedev AV, Misukonis M, Weinberg JB, Cao W, Robidoux J, Floering LM, Daniel KW, Collins S. Persistent NF-kappa B activation in Ucp2-/-mice leads to enhanced nitric oxide and inflammatory cytokine production.
J. Biol. Chem. 280: 19062-19069 (2005).
*
-
Bailey M, Haverson K, Inman C, Harris C, Jones P, Corfield G, Miller B, Stokes C. The development of the mucosal immune system pre- and post-weaning: balancing regulatory and effector function.
Proc. Nutr. Soc. 64: 451-457 (2005).
*
-
Bailey-Dell KJ, Hassel B, Doyle LA, Ross DD. Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene.
Biochim. Biophys. Acta 1520: 234-241 (2001).
*
-
Baillat D, Leprivier G, Regnier D, Vintonenko N, Begue A, Stehelin D, Aumercier M. Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter.
Oncogene 25: 5764-5776 (2006).
*
-
Baillie RA, Jump DB, Clarke SD. Specific effects of polyunsaturated fatty acids on gene expression.
Curr. Opin. Lipidol. 7: 53-55 (1996).
-
Bailly A, Briancon N, Weiss MC. Characterization of glucocorticoid receptor and hepatocyte nuclear factor 4alpha (HNF4alpha) binding to the hnf4alpha gene in the liver.
Biochimie 91: 1095-103 (2009).
-
Bailly-Maitre B, Fondevila C, Kaldas F, Droin N, Luciano F, Ricci JE, Croxton R, Krajewska M, Zapata JM, Kupiec-Weglinski JW, Farmer D, Reed JC. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury.
Proc. Natl. Acad. Sci. U.S.A. 103: 2809-2814 (2006).
*
-
Bailon E, Cueto-Sola M, Utrilla P, Rodriguez-Cabezas ME, Garrido-Mesa N, Zarzuelo A, Xaus J, Galvez J, Comalada M. Butyrate in vitro immune-modulatory effects might be mediated through a proliferation-related induction of apoptosis.
Immunobiology Jan 13 [Epub ahead of print] (2010).
-
Bain LJ, Feldman RA. Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice.
Xenobiotica 33: 1173-1183 (2005).
*
-
Bajmoczi M, Gadjeva M, Alper SL, Pier G, Golan DE. Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa.
Am. J. Physiol. Cell. Physiol. 297: C263-C277 (2009).
*
-
Bajwa A, Forster MA, Maiti A, Woolbright BL, Beckman MJ. Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells.
Arch. Biochem. Biophys. 477: 33-42 (2008).
*
-
Bak H, Lee WJ, Lee YW, Chang SE, Choi JH, Kim MN, Kim BJ, Choi YS, Suh HS. Expression of neuropeptides and their degrading enzymes in ACD.
Clin. Exp. Dermatol. Dec 16 [Epub ahead of print] (2009).
*
-
Bak-Romaniszyn L, Cedzynski M, Szemraj J, St Swierzko A, Zeman K, Kaluzynski A, Planeta-Malecka I. Mannan-binding lectin in children with chronic gastritis.
Scand. J. Immunol. 63: 131-135 (2006).
*
-
Bakalov VK, Cheng C, Zhou J, Bondy CA. X-chromosome gene dosage and the risk of diabetes in Turner syndrome.
J. Clin. Endocrinol. Metab. 94: 3289-3296 (2009).
-
Baken KA, Ezendam J, Gremmer ER, de Klerk A, Pennings JL, Matthee B, Peijnenburg AA, van Loveren H. Evaluation of immunomodulation by Lactobacillus casei Shirota: immune function, autoimmunity and gene expression.
Int. J. Food Microbiol. 112: 8-18 (2006).
*
-
Baker KP. BLyS-an essential survival factor for B cells: basic biology, links to pathology and therapeutic target.
Autoimmun. Rev. 3: 368-375 (2004).
-
Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Fatty acid transduction of nitric oxide signaling: identification of unsaturated fatty acid nitro derivatives and PPAR receptor-dependent signaling activity.
J. Biol. Chem. 280: 42464-42475 (2005).
*
-
Bakir F, Kher S, Pannala M, Wilson N, Nguyen T, Sircar I, Takedomi K, Fukushima C, Zapf J, Xu K, Zhang SH, Liu J, Morera L, Schneider L, Sakurai N, Jack R, Cheng JF. Discovery and structure-activity relationship studies of indole derivatives as liver X receptor (LXR) agonists.
Bioorg. Med. Chem. Lett. 17: 3473-3479 (2007).
*
-
Balaban YH, Korkusuz P, Simsek H, Gokcan H, Gedikoglu G, Pinar A, Hascelik G, Asan E, Hamaloglu E, Tatar G. Dipeptidyl peptidase IV (DDP IV) in NASH patients.
Ann. Hepatol. 6: 242-250 (2007).
*
-
Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, Miller SD, Popko B. Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis.
J. Neurosci. 27: 2013-2024 (2007).
*
-
Balabanov R, Strand K, Kemper A, Lee JY, Popko B. Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma.
J. Neurosci. 26: 5143-5152 (2006).
-
Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Rosa-Leyva M, Vilardell-Tarres M. Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus.
Immunology 124: 339-347 (2008).
*
-
Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Vilardell-Tarres M. Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients.
J. Leukoc. Biol. 81: 1609-1616 (2007).
*
-
Balada E, Ordi-Ros J, Vilardell-Tarres M. Molecular mechanisms mediated by human endogenous retroviruses (HERVs) in autoimmunity.
Rev. Med. Virol. 19: 273-286 (2009).
-
Balada E, Ordi-Ros J, Vilardell-Tarres M. DNA methylation and systemic lupus erythematosus.
Ann. N. Y. Acad. Sci. 1108: 127-136 (2007).
*
-
Balague C, Kunkel SL, Godessart N. Understanding autoimmune disease: new targets for drug discovery.
Drug Discov. Today 14: 926-934 (2009).
-
Balakathiresan NS, Bhattacharyya S, Gutti U, Long RP, Jozwik C, Huang W, Srivastava M, Pollard HB, Biswas R. Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells.
Am. J. Physiol. Lung Cell. Mol. Physiol. 296: L1012-L018 (2009).
*
-
Balakrishnan A, Sussman DJ, Polli JE. Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT).
Pharm. Res. 22: 1269-1280 (2005).
*
-
Balamurugan K, Luu VD, Kaufmann MR, Hofmann VS, Boysen G, Barth S, Bordoli MR, Stiehl DP, Moch H, Schraml P, Wenger RH, Camenisch G. Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response.
Oncogene 28: 3274-3285 (2009).
*
-
Balandraud N, Gouret P, Danchin EG, Blanc M, Zinn D, Roudier J, Pontarotti P. A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example.
BMC Genomics 6: 153 (2005).
*
-
Balasa A, Gathungu G, Kisfali P, Smith EO, Cho JH, Melegh B, Kellermayer R. Assessment of DNA methylation at the interferon regulatory factor 5 (IRF5) promoter region in inflammatory bowel diseases.
Int. J. Colorectal Dis. Feb 2 [Epub ahead of print] (2010).
*
-
Balasubramaniyan N, Shahid M, Suchy FJ, Ananthanarayanan M. Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development.
Am. J. Physiol. Gastrointest. Liver Physiol. 288: G251-G260 (2005).
*
-
Baldan A, Bojanic DD, Edwards PA. The ABCs of sterol transport.
J. Lipid Res. 50: S80-S85 (2009).
*
-
Baldan A, Relat J, Marrero PF, Haro D. Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation.
Nucleic Acids Res. 32: 4742-4749 (2004).
*
-
Baldan A, Tarr P, Lee R, Edwards PA. ATP-binding cassette transporter G1 and lipid homeostasis.
Curr. Opin. Lipidol. 17: 227-232 (2006).
-
Baldwin GC, Mickelson EM, Hansen JA, Nisperos B, Antonelli P, Nepom BS, Nepom GT. Electrophoretic variation between class II molecules expressed on HLA-DRw8 homozygous typing cells reveals multiple distinct haplotypes.
Immunogenetics 21: 49-60 (1985).
-
Balesaria S, Pell RJ, Abbott LJ, Tasleem A, Chavele KM, Barley NF, Khair U, Simon A, Moriarty KJ, Brydon WG, Walters JR. Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea.
Eur. J. Gastroenterol. Hepatol. 20: 413-422 (2008).
-
Balint BL, Nagy L. Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases.
Endocr. Metab. Immune Disord. Drug Targets 6: 33-43 (2006).
-
Balistreri WF. Genetic liver disease.
54th Annual Meeting of the American Association for the Study of Liver Diseases (2003).
-
Balkhi MY, Fitzgerald KA, Pitha PM. Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination.
Mol. Cell. Biol. 28: 7296-7308 (2008).
*
-
Balladares S, Alaez C, Pujol J, Duran C, Navarro JL, Gorodezky C. Distribution of TAP gene polymorphisms and extended MHC haplotypes in Mexican Mestizos and in Seri Indians from northwest Mexico.
Genes Immun. 3: 78-85 (2002).
*
-
Ballardini G, Bianchi FB, Mirakian R, Fallani M, Pisi E, Bottazzo GF. HLA-A,B,C, HLA-D/DR and HLA-D/DQ expression on unfixed liver biopsy sections from patients with chronic liver disease.
Clin. Exp. Immunol. 70: 35-46 (1987).
*
-
Ballardini G, Mirakian R, Bianchi FB, Pisi E, Doniach D, Bottazzo GF. Aberrant expression of HLA-DR antigens on bileduct epithelium in primary biliary cirrhosis: relevance to pathogenesis.
Lancet 2: 1009-1013 (1984).
-
Ballatori N, Fang F, Christian WV, Li N, Hammond CL. Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver.
Am. J. Physiol. Gastrointest. Liver Physiol. 295: G179-G186 (2008).
*
-
Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases.
Biol. Chem. 390: 191-214 (2009).
*
-
Balliet RM, Chen G, Dellinger RW, Lazarus P. UGT1A10: activity against the tobacco-specific nitrosamine, NNAL, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.
Drug Metab. Dispos. Dec 14 [Epub ahead of print] (2009).
*
-
Baluk P, Yao LC, Feng J, Romano T, Jung SS, Schreiter JL, Yan L, Shealy DJ, McDonald DM. TNF-alpha drives remodeling of blood vessels and lymphatics in sustained airway inflammation in mice.
J. Clin. Invest. 119: 2954-2964 (2009).
*
-
Bamba S, Lee CY, Brittan M, Preston S, Direkze N, Poulsom R, Alison M, Wright N, Otto W. Bone marrow transplantation ameliorates pathology in interleukin-10 knockout colitic mice.
J. Pathol. 209: 265-273 (2006).
*
-
Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F. Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation.
Gastroenterology 128: 654-666 (2005).
*
-
Bamias G, Okazawa A, Rivera-Nieves J, Arseneau KO, De La Rue SA, Pizarro TT, Cominelli F. Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis.
J. Immunol. 178: 1809-1818 (2007).
*
-
Ban H, Inoue M, Griesenbach U, Munkonge F, Chan M, Iida A, Alton EW, Hasegawa M. Expression and maturation of Sendai virus vector-derived CFTR protein: functional and biochemical evidence using a GFP-CFTR fusion protein.
Gene Ther. 14: 1688-1694 (2007).
*
-
Ban JO, Hwang IG, Kim TM, Hwang BY, Lee US, Jeong HS, Yoon YW, Kimz DJ, Hong JT. Anti-proliferate and pro-apoptotic effects of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyranone through inactivation of NF-kappaB in human colon cancer cells.
Arch. Pharm. Res. 30: 1455-1463 (2007).
-
Ban Y, Ban Y, Taniyama M, Katagiri T. Vitamin D receptor initiation codon polymorphism in Japanese patients with Graves' disease.
Thyroid 10: 475-480 (2000).
-
Ban Y, Ban Y, Taniyama M, Katagiri T. Vitamin D receptor initiation codon polymorphism in Japanese patients with Graves' disease.
Thyroid 10: 375-380 (2000).
-
Ban Y, Davies TF, Greenberg DA, Concepcion ES, Tomer Y. The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families.
Clin. Endocrinol. (Oxf.) 57: 81-88 (2002).
*
-
Ban Y, Tozaki T, Tobe T, Ban Y, Jacobson EM, Concepcion ES, Tomer Y. The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts.
J. Autoimmun. 28: 201-207 (2007).
-
Banach-Petrosky W, Ouyang X, Gao H, Nader K, Ji Y, Suh N, Dipaola RS, Abate-Shen C. Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1; Pten mutant mice.
Clin. Cancer Res. 12: 5895-5901 (2006).
*
-
Banales JM, Masyuk TV, Bogert PS, Huang BQ, Gradilone SA, Lee SO, Stroope AJ, Masyuk AI, Medina JF, LaRusso NF. Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease.
Am. J. Pathol. 173: 1637-1646 (2008).
*
-
Banan A, Zhang L, Farhadi A, Fields JZ, Shaikh M, Forsyth CB, Choudhary S, Keshavarzian A. Critical role of the atypical lambda ({lambda}) isoform of PKC (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium.
J. Pharmacol. Exp. Ther. 312: 458-471 (2005).
*
-
Bandiera S, Hatem E, Lyonnet S, Henrion-Caude A. microRNAs in diseases: from candidate to modifier genes.
Clin. Genet. Jan 5 [Epub ahead of print] (2010).
*
-
Bandyopadhyay S, Soto-Nieves N, Macian F. Transcriptional regulation of T cell tolerance.
Semin. Immunol. 19: 180-187 (2007).
*
-
Banerjee A, Gerondakis S. Coordinating TLR-activated signaling pathways in cells of the immune system.
Immunol. Cell Biol. 85: 420-424 (2007).
*
-
Banerjee A, Gugasyan R, McMahon M, Gerondakis S. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells.
Proc. Natl. Acad. Sci. U.S.A. 103: 3274-3279 (2006).
*
-
Banerjee A, Hussainzada N, Khandelwal A, Swaan PW. Electrostatic and potential cation-pi forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter.
Biochem. J. 410: 391-400 (2008).
*
-
Banerjee A, Ray A, Chang C, Swaan PW. Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2).
Biochemistry 44: 8908-8917 (2005).
*
-
Banerjee S, Oneda B, Yap LM, Jewell DP, Matters GL, Fitzpatrick LR, Seibold F, Sterchi EE, Ahmad T, Lottaz D, Bond JS. MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease.
Mucosal Immunol. 2: 220-231 (2009).
*
-
Bangsow C, Rubins N, Glusman G, Bernstein Y, Negreanu V, Goldenberg D, Lotem J, Ben-Asher E, Lancet D, Levanon D, Groner Y. The RUNX3 gene - sequence, structure and regulated expression.
Gene 279: 221-232 (2001).
-
Baniyash M. TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response.
Nat. Rev. Immunol. 4: 675-687 (2004).
*
-
Banks C, Bateman A, Payne R, Johnson P, Sheron N. Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.
J. Pathol. 199: 28-35 (2003).
*
-
Banks KE, Anderson AL, Tang H, Hughes DE, Costa RH, McLachlan A. Hepatocyte nuclear factor 3beta inhibits hepatitis B virus replication in vivo.
J. Virol. 76: 12974-12980 (2002).
*
-
Bannerman DD, Eiting KT, Winn RK, Harlan JM. FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide.
Am. J. Pathol. 165: 1423-1431 (2004).
*
-
Bannerman PG, Hahn A. Enhanced visualization of axonopathy in EAE using thy1-YFP transgenic mice.
J. Neurol. Sci. 260: 23-32 (2007).
-
Banno T, Gazel A, Blumenberg M. Pathway-specific profiling identifies the NFkB-dependent TNFa-regulated genes in epidermal keratinocytes.
J. Biol. Chem. 280: 18973-18980 (2005).
*
-
Banno T, Gazel A, Blumenberg M. Effects of tumor necrosis factor-alpha (TNFalpha) in epidermal keratinocytes revealed using global transcriptional profiling.
J. Biol. Chem. 279: 32633-32642 (2004).
*
-
Bansal K, Narayana Y, Balaji KN. Inhibition of TNF-alpha-induced cyclooxygenase-2 expression by Mycobacterium bovis BCG in human alveolar epithelial A549 cells.
Scand. J. Immunol. 69: 11-19 (2009).
*
-
Bansal MB, Kovalovich K, Gupta R, Li W, Agarwal A, Radbill B, Alvarez CE, Safadi R, Fiel MI, Friedman SL, Taub RA. Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression.
J. Hepatol. 42: 548-556 (2005).
*
-
Bansal T, Alaniz RC, Wood TK, Jayaraman A. The bacterial signal indole increases epithelial-cell tight-junction resistance and attenuates indicators of inflammation.
Proc. Natl. Acad. Sci. U.S.A. Dec 4 [Epub ahead of print] (2009).
*
-
Bantel H, Berg C, Vieth M, Stolte M, Kruis W, Schulze-Osthoff K. Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis.
Am. J. Gastroenterol. 95: 3452-3457 (2000).
*
-
Bantis C, Heering PJ, Aker S, Schwandt C, Grabensee B, Ivens K. Influence of interleukin-10 gene G-1082A polymorphism on recurrent IgA nephropathy.
J. Nephrol. 21: 941-946 (2008).
-
Bantis C, Heering PJ, Aker S, Siekierka M, Kuhr N, Grabensee B, Ivens K. Tumor necrosis factor-alpha gene G-308A polymorphism is a risk factor for the development of membranous glomerulonephritis.
Am. J. Nephrol. 26: 12-15 (2006).
-
Banus HA, Vandebriel RJ, de Ruiter H, Dormans JA, Nagelkerke NJ, Mooi FR, Hoebee B, van Kranen HJ, Kimman TG. Host genetics of Bordetella pertussis infection in mice: significance of Toll-like receptor 4 in genetic susceptibility and pathobiology.
Infect. Immun. 74: 2596-2605 (2006).
*
-
Banus S, Pennings J, Vandebriel R, Wester P, Breit T, Mooi F, Hoebee B, Kimman T. Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling.
Immunogenetics 59: 555-564 (2007).
*
-
Banyer JL, Halliday DC, Thomson SA, Hamilton NH. Combinations of IFN-gamma and IL-4 induce distinct profiles of dendritic cell-associated immunoregulatory properties.
Genes Immun. 4: 427-440 (2003).
*
-
Bao C, Guo J, Lin G, Hu M, Hu Z. TNFR gene-modified mesenchymal stem cells attenuate inflammation and cardiac dysfunction following MI.
Scand. Cardiovasc. J. 42: 56-62 (2008).
-
Bao J, Wang Q, Zheng L, Qiu YR, Zeng FY, Yang CL, Huang XZ. RelB silencing in mouse bone-marrow derived dendritic cells mediated by lentiviral vector.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24: 857-860 (2008).
-
Bao L, Osawe I, Puri T, Lambris JD, Haas M, Quigg RJ. C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist.
Eur. J. Immunol. 35: 2496-2506 (2005).
*
-
Bao L, Wang Y, Chen P, Sarav M, Haas M, Minto AW, Petkova M, Quigg RJ. Mesangial cell complement receptor 1-related protein y limits complement-dependent neutrophil accumulation in immune complex glomerulonephritis.
Immunology 128: e895-e904 (2009).
-
Bao L, Zhou M, Wu L, Lu L, Goldowitz D, Williams RW, Cui Y. PolymiRTS database: linking polymorphisms in microRNA target sites with complex traits.
Nucleic Acids Res. 35: D51-D54 (2007).
*
-
Bao S, Beagley KW, Murray AM, Caristo V, Matthaei KI, Young IG, Husband AJ. Intestinal IgA plasma cells of the B1 lineage are IL-5 dependent.
Immunology 94: 181-188 (1998).
*
-
Bar-Yehuda S, Silverman MH, Kerns WD, Ochaion A, Cohen S, Fishman P. The anti-inflammatory effect of A(3) adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis.
Expert Opin. Investig. Drugs 16: 1601-1613 (2007).
-
Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones DEJ, Donaldson PT, Bassendine MF. Chemokine receptor 5 and primary biliary cirrhosis: a two-centre genetic association study.
Liver Int. 24: 646-650 (2004).
*
-
Baran W, Szepietowski JC, Mazur G, Baran E. TGF-beta(1) gene polymorphism in psoriasis vulgaris.
Cytokine 38: 8-11 (2007).
-
Baran W, Szepietowski JC, Mazur G, Baran E. IL-6 and IL-10 promoter gene polymorphisms in psoriasis vulgaris.
Acta Derm. Venereol. 88: 113-116 (2008).
*
-
Baranek T, Debret R, Antonicelli F, Lamkhioued B, Belaaouaj A, Hornebeck W, Bernard P, Guenounou M, Le Naour R. Elastin receptor (spliced galactosidase) occupancy by elastin peptides counteracts proinflammatory cytokine expression in lipopolysaccharide-stimulated human monocytes through NF-kappaB down-regulation.
J. Immunol. 179: 6184-6192 (2007).
*
-
Baranova A, Liotta L, Petricoin E, Younossi ZM. The role of genomics and proteomics: technologies in studying non-alcoholic fatty liver disease.
Clin. Liver Dis.11: 209-220 (2007).
-
Baranska M, Skretkowicz J. Prospects of gene therapy.
Wiad. Lek. 60: 305-311 (2007).
-
Bararia D, Trivedi AK, Zada AA, Greif PA, Mulaw MA, Christopeit M, Hiddemann W, Bohlander SK, Behre G. Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.
Leukemia 22: 800-807 (2008).
-
Baratelli F, Lin Y, Zhu L, Yang SC, Heuze-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells.
J. Immunol. 175: 1483-1490 (2005).
*
-
Barbas AS, Lesher AP, Thomas A, Wyse A, Devalapalli AP, Lee YH, Tan HE, Orndorff PE, Parker W, Bollinger RR. Altering and assessing persistence of genetically modified E. coli MG1655 in the large bowel.
Exp. Biol. Med. (Maywood) 234: 1174-1185 (2009).
-
Barbaux S, Poirier O, Godefroy T, Kleinert H, Blankenberg S, Cambien F, Tiret L. Differential haplotypic expression of the interleukin-18 gene.
Eur. J. Hum. Genet. 15: 856-863 (2007).
*
-
Barbe-Tuana FM, Klein D, Ichii H, Berman DM, Coffey L, Kenyon NS, Ricordi C, Pastori RL. CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets.
Diabetes 55: 2437-2445 (2006).
*
-
Barbeau WE, Bassaganya-Riera J, Hontecillas R. Putting the pieces of the puzzle together - a series of hypotheses on the etiology and pathogenesis of type 1 diabetes.
Med. Hypotheses 68: 607-619 (2007).
-
Barbera MJ, Schluter A, Pedraza N, Iglesias R, Villarroya F, Giralt M. Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell.
J. Biol. Chem. 276: 1486-1493 (2001).
*
-
Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, Staels B. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme.
J. Biol. Chem. 278: 32852-32860 (2003).
*
-
Barbier O, Torra IP, Duguay Y, Blanquart C, Fruchart JC, Glineur C, Staels B. Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis.
Arterioscler. Thromb. Vasc. Biol. 22: 717-726 (2002).
*
-
Barbier O, Torra IP, Sirvent A, Claudel T, Blanquart C, Duran-Sandoval D, Kuipers F, Kosykh V, Fruchart JC, Staels B. FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity.
Gastroenterology 124: 1926-1940 (2003).
*
-
Barbier O, Trottier J, Kaeding J, Caron P, Verreault M. Lipid-activated transcription factors control bile acid glucuronidation.
Mol. Cell. Biochem. 326: 3-8 (2009).
*
-
Barbier O, Villeneuve L, Bocher V, Fontaine C, Torra IP, Duhem C, Kosykh V, Fruchart JC, Guillemette C, Staels B. The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene.
J. Biol. Chem. 278: 13975-13983 (2003).
*
-
Barbon A, Gervasoni A, Lavia L, Orlandi C, Jaskolski F, Perrais D, Barlati S. Human GluR6c, a functional splicing variants of GluR6, is mainly expressed in non-nervous cells.
Neurosci. Lett. 434: 77-82 (2008).
-
Barbosa KV, de Souza AF, Chebli JM, Proietti FA, Meirelles RS, de Souza JL. Hereditary hemochromatosis: population screening based on phenotype in Brazilian blood donors.
J. Clin. Gastroenterol. 39: 430-434 (2005).
-
Barcellos LF, Oksenberg JR, Begovich AB, Martin ER, Schmidt S, Vittinghoff E, Goodin DS, Pelletier D, Lincoln RR, Bucher P, Swerdlin A, Pericak-Vance MA, Haines JL, Hauser SL; Multiple Sclerosis Genetics Group. HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course.
Am. J. Hum. Genet. 72: 710-716 (2003).
*
-
Barcellos LF, Oksenberg JR, Green AJ, Bucher P, Rimmler JB, Schmidt S, Garcia ME, Lincoln RR, Pericak-Vance MA, Haines JL, Hauser SL; Multiple Sclerosis Genetics Group. Genetic basis for clinical expression in multiple sclerosis.
Brain 125: 150-158 (2002).
*
-
Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Ucelli A, Savettieri G, Lincoln RL, Deloa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis.
Hum. Mol. Genet. 15: 2813-2824 (2006).
*
-
Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shih A, Lincoln R, Callier S, Elkins MK, Goodkin DE, Haines JL, Pericak-Vance MA, Hauser SL, Oksenberg JR. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group.
Immunogenetics 51: 281-288 (2000).
-
Barcelo-Coblijn G, Golovko MY, Weinhofer I, Berger J, Murphy EJ. Brain neutral lipids mass is increased in alpha-synuclein gene-ablated mice.
J. Neurochem. 101: 132-141 (2007).
-
Barcelo-Coblijn G, Kitajka K, Puskas LG, Hogyes E, Zvara A, Hackler L Jr, Farkas T. Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio.
Biochim. Biophys. Acta 1632: 72-79 (2003).
*
-
Barchet W, Wimmenauer V, Schlee M, Hartmann G. Accessing the therapeutic potential of immunostimulatory nucleic acids.
Curr. Opin. Immunol. 20: 389-395 (2008).
-
Bardin N, Reumaux D, Geboes K, Colombel JF, Blot-Chabaud M, Sampol J, Duthilleul P, Dignat-George F. Increased expression of CD146, a new marker of the endothelial junction in active inflammatory bowel disease.
Inflamm. Bowel Dis. 12: 16-21 (2006).
*
-
Bardon S, Benelli C, Bernard-Gallon D, Blottiere H, Demarquoy J, Duee PH, Forest C. Dietary fatty acids and cancer: potential cellular and molecular mechanisms.
Bull. Cancer 92: 697-707 (2005).
-
Bari R, Bell T, Leung WH, Vong QP, Chan WK, Das Gupta N, Holladay M, Rooney B, Leung W. Significant functional heterogeneity among KIR2DL1 alleles and a pivotal role of arginine 245.
Blood 114: 5182-5190 (2009).
*
-
Baricordi OR, Stignani M, Melchiorri L, Rizzo R. HLA-G and inflammatory diseases.
Inflamm. Allergy Drug Targets 7: 67-74 (2008).
-
Barile S, Medda E, Nistico L, Bordignon V, Cordiali-Fei P, Carducci M, Rainaldi A, Marinelli R, Bonifati C. Vascular endothelial growth factor gene polymorphisms increase the risk to develop psoriasis.
Exp. Dermatol. 15: 368-376 (2006).
*
-
Barisani D, Ceroni S, Meneveri R, Cesana BM, Bardella MT. IL-10 polymorphisms are associated with early-onset celiac disease and severe mucosal damage in patients of Caucasian origin.
Genet. Med. 8: 169-174 (2006).
-
Barish GD. Peroxisome proliferator-activated receptors and liver X receptors in atherosclerosis and immunity.
J. Nutr. 136: 690-694 (2006).
*
-
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis.
Proc. Natl. Acad. Sci. U.S.A. 105: 4271-4276 (2008).
*
-
Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A nuclear receptor atlas: macrophage activation.
Mol. Endocrinol. 19: 2466-2477 (2005).
*
-
Barish GD, Narkar VA, Evans RM. PPARdelta: a dagger in the heart of the metabolic syndrome.
J. Clin. Invest. 116: 590-597 (2006).
*
-
Barkauskaite V, Ek M, Popovic K, Harris HE, Wahren-Herlenius M, Nyberg F. Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus.
Lupus 16: 794-802 (2007).
*
-
Barker CL, McHale MT, Gillies AK, Waller J, Pearce DM, Osborne J, Hutchinson PE, Smith GM, Pringle JH. The development and characterization of an in vitro model of psoriasis.
J. Invest. Dermatol. 123: 892-901 (2004).
*
-
Barker DF, Husain A, Neale JR, Martini BD, Zhang X, Doll MA, Christopher States J, Hein DW. Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1.
Pharmacogenet. Genomics 16: 515-525 (2006).
*
-
Barker JN. Genetic aspects of psoriasis.
Clin. Exp. Dermatol. 26: 321-325 (2001).
*
-
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Identification of stem cells in small intestine and colon by marker gene Lgr5.
Nature 449: 1003-1007 (2007).
*
-
Barksby HE, Lea SR, Preshaw PM, Taylor JJ. The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders.
Clin. Exp. Immunol. 149: 217-225 (2007).
*
-
Barksby HE, Milner JM, Patterson AM, Peake NJ, Hui W, Robson T, Lakey R, Middleton J, Cawston TE, Richards CD, Rowan AD. Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis.
Arthritis Rheum. 54: 3244-3253 (2006).
*
-
Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM. Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide.
Clin. Exp. Immunol. 156: 479-487 (2009).
*
-
Barlic J, Zhang Y, Foley JF, Murphy PM. Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway.
Circulation 114: 807-819 (2006).
-
Barlow AK, He X, Janeway C Jr. Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells.
J. Exp. Med. 187: 1403-1415 (1998).
*
-
Barna BP, Malur A, Dalrymple H, Karnekar R, Culver DA, Abraham S, Singh RJ, Brescia D, Kavuru MS, Thomassen MJ. A novel 1,25-dihydroxyvitamin D-activin A pathway in human alveolar macrophages is dysfunctional in patients with pulmonary alveolar proteinosis (PAP).
Autoimmunity 42: 56-62 (2009).
-
Barnes B, Lubyova B, Pitha PM. On the role of IRF in host defense.
J. Interferon Cytokine Res. 22: 59-71 (2002).
-
Barnes BJ, Field AE, Pitha-Rowe PM. Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes.
J. Biol. Chem. 278: 16630-16641 (2003).
*
-
Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, Pitha PM. Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection.
J. Biol. Chem. 279: 45194-45207 (2004).
*
-
Barnes KC, Grant A, Gao P, Baltadjieva D, Berg T, Chi P, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, Brummet ME, Stockton M, Watkins T, Gao L, Gittens M, Wills-Karp M, Cheadle C, Beck LA, Beaty TH, Becker KG, Garcia JG, Mathias RA. Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes.
J. Allergy Clin. Immunol. 118: 70-77 (2006).
*
-
Barnes NA, Stephenson SJ, Tooze RM, Doody GM. Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase.
J. Immunol. 183: 5768-5777 (2009).
-
Barnes PJ. How corticosteroids control inflammation: Quintiles Prize Lecture 2005.
Br. J. Pharmacol. 148: 245-254 (2006).
*
-
Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken M, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE. Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases.
Drug Metab. Dispos. 35: 1963-1969 (2007).
*
-
Barnholt KE, Kota RS, Aung HH, Rutledge JC. Adenosine blocks IFN-gamma-induced phosphorylation of STAT1 on serine 727 to reduce macrophage activation.
J. Immunol. 183: 6767-6777 (2009).
-
Barnich N, Bringer MA, Claret L, Darfeuille-Michaud A. Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease.
Infect. Immun. 72: 2484-2493 (2004).
*
-
Barnich N, Darfeuille-Michaud A. Role of bacteria in the etiopathogenesis of inflammatory bowel disease.
World J. Gastroenterol. 13: 5571-5576 (2007).
*
-
Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK. GRIM-19 interacts with NOD2 and serves as down-stream effector of anti-bacterial function in intestinal epithelial cells.
J. Biol. Chem. 280: 19021-19026 (2005).
*
-
Baron M, Davignon JL. Inhibition of IFN-gamma-induced STAT1 tyrosine phosphorylation by human CMV is mediated by SHP2.
J. Immunol. 181: 5530-5536 (2008).
*
-
Barone F, Bombardieri M, Manzo A, Blades MC, Morgan PR, Challacombe SJ, Valesini G, Pitzalis C. Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjogren's syndrome.
Arthritis Rheum. 52: 1773-1784 (2005).
*
-
Baroni A, Orlando M, Donnarumma G, Farro P, Iovene MR, Tufano MA, Buommino E. Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur.
Arch. Dermatol. Res. 297: 280-288 (2006).
*
-
Baroni SS, Santillo M, Bevilacqua F, Luchetti M, Spadoni T, Mancini M, Fraticelli P, Sambo P, Funaro A, Kazlauskas A, Avvedimento EV, Gabrielli A. Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis.
N. Engl. J. Med. 354: 2667-2676 (2006).
*
-
Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, Batalov S, Liu Y, Warmuth M, Wiltshire T, Cooke MP, Sauer K. A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function.
Mol. Cell 33: 43-52 (2009).
*
-
Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines.
J. Biol. Chem. 282: 19575-19588 (2007).
*
-
Barr TA, Brown S, Mastroeni P, Gray D. B cell intrinsic MyD88 signals drive IFN-gamma production from T cells and control switching to IgG2c.
J. Immunol. 183: 1005-1012 (2009).
-
Barra GB, Velasco LF, Pessanha RP, Campos AM, Moura FN, Dias SM, Polikarpov I, Ribeiro RC, Simeoni LA, Neves FA. Molecular mechanism of thyroid hormone action.
Arq. Bras. Endocrinol. Metabol. 48: 25-39 (2004).
-
Barrera G, Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, Dianzani MU, Ferretti C. The role of PPAR ligands in controlling growth-related gene expression and their interaction with lipoperoxidation products.
PPAR Res. 2008: 524671 (2008).
*
-
Barresi V, Grosso M, Vitarelli E, Tuccari G, Barresi G. 5-Lipoxygenase is coexpressed with Cox-2 in sporadic colorectal cancer: a correlation with advanced stage.
Dis. Colon Rectum 50: 1576-1584 (2007).
*
-
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease.
Nat. Genet. 40: 955-962 (2008).
*
-
Barriere H, Bagdany M, Bossard F, Okiyoneda T, Wojewodka G, Gruenert D, Radzioch D, Lukacs GL. Revisiting the role of cystic fibrosis transmembrane conductance regulator and counterion permeability in the pH regulation of endocytic organelles.
Mol. Biol. Cell 20: 3125-3141 (2009).
*
-
Barro Soria R, Spitzner M, Schreiber R, Kunzelmann K. Bestrophin 1 enables Ca2+ activated Cl- conductance in epithelia.
J. Biol. Chem. 284: 29405-29412 (2009).
*
-
Bartee E, McCormack A, Fruh K. Quantitative membrane proteomics reveals new cellular targets of viral immune modulators.
PLoS Pathog. 2: e107 (2006).
*
-
Bartholin L, Cyprian FS, Vincent D, Garcia CN, Martel S, Horvat B, Berthet C, Goddard-Leon S, Treilleux I, Rimokh R, Marie JC. Generation of mice with conditionally activated transforming growth factor beta signaling through the TbetaRI/ALK5 receptor.
Genesis 46: 724-731 (2008).
*
-
Bartholin L, Powers SE, Melhuish TA, Lasse S, Weinstein M, Wotton D. TGIF inhibits retinoid signaling.
Mol. Cell. Biol. 26: 990-1001 (2006).
*
-
Bartke A, Bonkowski M, Masternak M. THow diet interacts with longevity genes.
Hormones (Athens) 7: 17-23 (2008).
-
Bartling TR, Drumm ML. Oxidative stress causes IL8 promoter hyperacetylation in cystic fibrosis airway cell models.
Am. J. Respir. Cell. Mol. Biol. 40: 58-65 (2009).
*
-
Bartling TR, Drumm ML. Loss of CFTR results in reduction of histone deacetylase 2 in airway epithelial cells.
Am. J. Physiol. Lung Cell. Mol. Physiol. 297: L35-L43 (2009).
*
-
Bartolome MJ, Martinez-Taboda VM, Lopez-Hoyos M, Blanco R, Rodriguez-Valverde V. Familial aggregation of polymyalgia rheumatica and giant cell arteritis: genetic and T cell repertoire analysis.
Clin. Exp. Rheumatol. 19: 259-264 (2001).
-
Barton GM, Medzhitov R. Toll-like receptors and their ligands.
Curr. Top. Microbiol. Immunol. 270: 81-92 (2002).
-
Barton SG, Rampton DS, Winrow VR, Domizio P, Feakins RM. Expression of heat shock protein 32 (hemoxygenase-1) in the normal and inflamed human stomach and colon: an immunohistochemical study.
Cell Stress Chaperones 8: 329-334 (2003).
*
-
Bartosch B, Thimme R, Blum HE, Zoulim F. Hepatitis C virus-induced hepatocarcinogenesis.
J. Hepatol. 51: 810-820 (2009).
-
Bartz H, Avalos NM, Baetz A, Heeg K, Dalpke AH. Involvement of suppressors of cytokine signaling in Toll-like receptor-mediated block of dendritic cell differentiation.
Blood 108: 4102-4108 (2006).
*
-
Baruah P, Dumitriu IE, Malik TH, Cook HT, Dyson J, Scott D, Simpson E, Botto M. C1q enhances IFN-gamma production by antigen specific T cells via the CD40 co-stimulatory pathway on dendritic cells.
Blood 113: 3485-3493 (2009).
*
-
Barzon L, Stefani AL, Pacenti M, Palu G. Versatility of gene therapy vectors through viruses.
Expert Opin. Biol. Ther. 5: 639-662 (2005).
-
Bas A, Forsberg G, Sjoberg V, Hammarstrom S, Hernell O, Hammarstrom ML. Aberrant extrathymic T cell receptor gene rearrangement in the small intestinal mucosa: a risk factor for celiac disease?
Gut 58: 189-195 (2009).
*
-
Basak GW, Yasukawa S, Alfaro A, Halligan S, Srivastava AS, Min WP, Minev B, Carrier E. Human embryonic stem cells-derived blast cells expres HLA-antigens.
J. Transl. Med. 7: 27 (2009).
*
-
Basak P, Adiloglu A, Koc I, Tas T, Akkaya V. Evaluation of activatory and inhibitory natural killer cell receptors in non-segmental vitiligo: a flow cytometric study.
J. Eur. Acad. Dermatol. Venereol. 22: 970-976 (2008).
*
-
Basarkar A, Singh J. Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice.
Pharm. Res. 26: 72-81 (2009).
*
-
Bashir MM, Sharma MR, Werth VP. TNF-alpha production in the skin.
Arch. Dermatol. Res. 301: 87-91 (2009).
*
-
Basinski TM, Holzmann D, Eiwegger T, Zimmermann M, Klunker S, Meyer N, Schmid-Grendelmeier P, Jutel M, Akdis CA. Dual nature of T-cell-epithelium interaction in chronic rhinosinusitis.
J. Allergy Clin. Immunol. 124: 74-80.e1-e8 (2009).
-
Basler T, Geffers R, Weiss S, Valentin-Weigand P, Goethe R. Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis.
Immunobiology 213: 879-888 (2008).
-
Basler T, Holtmann H, Abel J, Eckstein T, Baumer W, Valentin-Weigand P, Goethe R. Reduced transcript stabilization restricts TNF-alpha expression in RAW264.7 macrophages infected with pathogenic mycobacteria: evidence for an involvement of lipomannan.
J. Leukoc. Biol. Oct 22 [Epub ahead of print] (2009).
*
-
Basler T, Jeckstadt S, Valentin-Weigand P, Goethe R. Mycobacterium paratuberculosis, Mycobacterium smegmatis, and lipopolysaccharide induce different transcriptional and post-transcriptional regulation of the IRG1 gene in murine macrophages.
J. Leukoc. Biol. 79: 628-638 (2006).
*
-
Basma H, Soto-Gutierrez A, Yannam GR, Liu L, Ito R, Yamamoto T, Ellis E, Carson SD, Sato S, Chen Y, Muirhead D, Navarro-Alvarez N, Wong RJ, Roy-Chowdhury J, Platt JL, Mercer DF, Miller JD, Strom SC, Kobayashi N, Fox IJ. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes.
Gastroenterology 136: 990-999.e4 (2009).
*
-
Bass AJ, Watanabe H, Mermel CH, Yu S, Perner S, Verhaak RG, Kim SY, Wardwell L, Tamayo P, Gat-Viks I, Ramos AH, Woo MS, Weir BA, Getz G, Beroukhim R, O'Kelly M, Dutt A, Rozenblatt-Rosen O, Dziunycz P, Komisarof J, Chirieac LR, Lafargue CJ, et al. SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas.
Nat. Genet. 41: 1238-1242 (2009).
*
-
Bassaganya-Riera J, Hontecillas R. CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD.
Clin. Nutr. 25: 454-465 (2006).
-
Bassaganya-Riera J, Hontecillas R, Beitz DC. Colonic anti-inflammatory mechanisms of conjugated linoleic acid.
Clin. Nutr. 21: 451-459 (2002).
-
Bassaganya-Riera J, Misyak S, Guri AJ, Hontecillas R. PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation.
Cell. Immunol. 258: 138-146 (2009).
*
-
Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui Y, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU, Hontecillas R. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease.
Gastroenterology 127: 777-791 (2004).
*
-
Bassendine MF. Infectious etiology of primary biliary cirrhosis (PBC).
Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 45-46 (2004). *
-
Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR, Rainey WE. The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase: implications for the control of adrenal functional zonation.
J. Biol. Chem. 279: 37622-37630 (2004).
*
-
Bassi MT, Manzoni M, Bresciani R, Pizzo MT, Della Monica A, Barlati S, Monti E, Borsani G. Cellular expression and alternative splicing of SLC25A23, a member of the mitochondrial Ca(2+)-dependent solute carrier gene family.
Gene 345: 173-182 (2005).
*
-
Basso K, Sumazin P, Morozov P, Schneider C, Maute RL, Kitagawa Y, Mandelbaum J, Haddad J Jr, Chen CZ, Califano A, Dalla-Favera R. Identification of the human mature B cell miRNome.
Immunity 30: 744-752 (2009).
*
-
Bassols J, Moreno JM, Ortega F, Ricart W, Fernandez-Real JM. Characterization of herpes virus entry mediator as a factor linked to obesity.
Obesity (Silver Spring) Aug 13 [Epub ahead of print] (2009).
*
-
Bassols J, Moreno-Navarrete JM, Ortega F, Ricart W, Fernandez-Real JM. LIGHT is associated with hypertriglyceridemia in obese subjects and increased cytokine secretion from cultured human adipocytes.
Int. J. Obes. (Lond.) Sep 29 [Epub ahead of print] (2009).
-
Bassols J, Ortega FJ, Moreno-Navarrete JM, Peral B, Ricart W, Fernandez-Real JM. Study of the proinflammatory role of human differentiated omental adipocytes.
J. Cell. Biochem. 107: 1107-1117 (2009).
*
-
Bastonero S, Gargouri M, Ortiou S, Gueant JL, Merten MD. Inhibition by TNF-alpha and IL-4 of cationic lipid mediated gene transfer in cystic fibrosis tracheal gland cells.
J. Gene Med. 7: 1439-1449 (2005).
-
Bastonero S, Le Priol Y, Armand M, Bernard CS, Reynaud-Gaubert M, Olive D, Parzy D, de Bentzmann S, Capo C, Mege JL. New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis.
PLoS ONE 4: e5357 (2009).
*
-
Basu D, Liu Y, Wu A, Yarlagadda S, Gorelik GJ, Kaplan MJ, Hewagama A, Hinderer RC, Strickland FM, Richardson BC. Stimulatory and inhibitory killer Ig-like receptor molecules are expressed and functional on lupus T cells.
J. Immunol. 183: 3481-3487 (2009).
-
Basu S, Pathak SK, Banerjee A, Pathak S, Bhattacharyya A, Yang Z, Talarico S, Kundu M, Basu J. Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha.
J. Biol. Chem. 282: 1039-1050 (2007).
*
-
Basu-Modak S, Braissant O, Escher P, Desvergne B, Honegger P, Wahli W. Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures.
J. Biol. Chem. 274: 35881-35888 (1999).
*
-
Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia.
J. Invest. Dermatol. 105: 89S-94S (1995).
-
Bataille F, Rohrmeier C, Bates R, Weber A, Rieder F, Brenmoehl J, Strauch U, Farkas S, Furst A, Hofstadter F, Scholmerich J, Herfarth H, Rogler G. Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease.
Inflamm. Bowel Dis. 14: 1514-1527 (2008).
*
-
Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis.
Semin. Liver Dis. 21: 437-451 (2001).
-
Bates IR, Libich DS, Wood DD, Moscarello MA, Harauz G. An Arg/Lys-->Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis.
Protein Expr. Purif. 25: 330-341 (2002).
*
-
Bates JM, Akerlund J, Mittge E, Guillemin K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota.
Cell Host Microbe 2: 371-382 (2007).
*
-
Bates JM, Mittge E, Kuhlman J, Baden KN, Cheesman SE, Guillemin K. Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation.
Dev. Biol. 297: 374-386 (2006).
*
-
Batheja N, Suriawinata A, Saxena R, Ionescu G, Schwartz M, Thung SN. Expression of p53 and PCNA in cholangiocarcinoma and primary sclerosing cholangitis.
Mod. Pathol. 13: 1265-1268 (2000).
*
-
Batista-Pinto C, Rocha E, Castro LF, Rodrigues P, Lobo-da-Cunha A. Seasonal and gender variation of peroxisome proliferator activated receptors expression in brown trout liver.
Gen. Comp. Endocrinol. 161: 146-152 (2009).
*
-
Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK. Peripheral blood gene expression profiling in rheumatoid arthritis.
Genes Immun. 6: 388-397 (2005).
*
-
Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, Laragione T, Shao T, Durham R, Kemshetti S, Schwarz E, Coe R, Kern M, Baechler EC, Behrens TW, Gregersen PK, Gulko PS. Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis.
Mol. Med. 11: 21-29 (2005).
*
-
Batra A, Zeitz M, Siegmund B. Adipokine signaling in inflammatory bowel disease.
Inflamm. Bowel Dis. 15: 1897-1905 (2009).
-
Batrakova EV, Kelly DL, Li S, Li Y, Yang Z, Xiao L, Alakhova DY, Sherman S, Alakhov VY, Kabanov AV. Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85.
Mol. Pharm. 3: 113-123 (2006).
*
-
Battaglia M, Roncarolo MG. The fate of human Treg cells.
Immunity 30: 763-765 (2009).
*
-
Batten M, Kljavin NM, Li J, Walter MJ, de Sauvage FJ, Ghilardi N. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells.
J. Immunol. 180: 2752-2756 (2008).
*
-
Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, Duncan SA. Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver.
Proc. Natl. Acad. Sci. U.S.A. 103: 8419-8424 (2006).
*
-
Baudouin-Legros M, Hamdaoui N, Borot F, Fritsch J, Ollero M, Planelles G, Edelman A. Control of basal CFTR gene expression by bicarbonate-sensitive adenylyl cyclase in human pulmonary cells.
Cell Physiol. Biochem. 21: 75-86 (2008).
*
-
Baudouin-Legros M, Hinzpeter A, Jaulmes A, Brouillard F, Costes B, Fanen P, Edelman A. Cell-specific posttranscriptional regulation of CFTR gene expression via the influence of MAP kinase cascades on the 3'UTR part of the transcripts.
Am. J. Physiol. Cell. Physiol. 289: C1240-C1250 (2005).
*
-
Bauer J, Liebisch G, Hofmann C, Huy C, Schmitz G, Obermeier F, Bock J. Lipid alterations in experimental murine colitis: role of ceramide and imipramine for matrix metalloproteinase-1 expression.
PLoS One 4: e7197 (2009).
*
-
Bauer JW, Bilgic H, Baechler EC. Gene-expression profiling in rheumatic disease: tools and therapeutic potential.
Nat. Rev. Rheumatol. 5: 257-265 (2009).
-
Bauer JW, Petri M, Batliwalla FM, Koeuth T, Wilson J, Slattery C, Panoskaltsis-Mortari A, Gregersen PK, Behrens TW, Baechler EC. Interferon-regulated chemokines as biomarkers of systemic lupus erythematosus disease activity: a validation study.
Arthritis Rheum. 60: 3098-3107 (2009).
*
-
Bauer M, Hamm AC, Bonaus M, Jacob A, Jaekel J, Schorle H, Pankratz MJ, Katzenberger JD. Starvation response in mouse liver shows strong correlation with life-span-prolonging processes.
Physiol. Genomics 17: 230-244 (2004).
*
-
Bauernfeind FG, Horvath G, Stutz A, Alnemri ES, Macdonald K, Speert D, Fernandes-Alnemri T, Wu J, Monks BG, Fitzgerald KA, Hornung V, Latz E. Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression.
J. Immunol. 183: 787-791 (2009).
-
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, Wolfe F, Gregersen PK, Bucala R. A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis.
Genes Immun. 3: 170-176 (2002).
*
-
Baum P, Fundel-Clemens K, Kreuz S, Kontermann RE, Weith A, Mennerich D, Rippmann JF. Off-target analysis of control siRNA molecules reveals important differences in the cytokine profile and inflammation response of human fibroblasts.
Oligonucleotides Dec 28 [Epub ahead of print] (2009).
-
Baum S, Barzilai A, Huszar M, Greenberger S, Trau H, Bank I. Very late antigen-1 in psoriasis: an immunohistochemical study.
J. Eur. Acad. Dermatol. Venereol. 22: 283-289 (2008).
*
-
Bauman DR, Bitmansour AD, McDonald JG, Thompson BM, Liang G, Russell DW. 25-Hydroxycholesterol secreted by macrophages in response to Toll-like receptor activation suppresses immunoglobulin A production.
Proc. Natl. Acad. Sci. U.S.A. 106: 16764-16769 (2009).
*
-
Baumann U, Schmidt RE, Gessner JE. New insights into the pathophysiology and in vivo function of IgG Fc receptors through gene deletion studies.
Arch. Immunol. Ther. Exp. (Warsz.) 51: 399-406 (2003).
-
Baumel M, Lechner A, Hehlgans T, Mannel DN. Enhanced susceptibility to Con A-induced liver injury in mice transgenic for the intracellular isoform of human TNF receptor type 2.
J. Leukoc. Biol. 84: 162-169 (2008).
*
-
Baumgardner JN, Shankar K, Korourian S, Badger TM, Ronis MJ. Undernutrition enhances alcohol-induced hepatocyte proliferation in the liver of rats fed via total enteral nutrition.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G355-G364 (2007).
*
-
Baumgart DC, Thomas S, Przesdzing I, Metzke D, Bielecki C, Lehmann SM, Lehnardt S, Dorffel Y, Sturm A, Scheffold A, Schmitz J, Radbruch A. Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease.
Clin. Exp. Immunol. 157: 423-436 (2009).
*
-
Baumhoer D, Tornillo L, Stadlmann S, Roncalli M, Diamantis EK, Terracciano LM. Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples.
Am. J. Clin. Pathol. 129: 899-906 (2008).
*
-
Baus-Loncar M, Lubka M, Pusch CM, Otto WR, Poulsom R, Blin N. Cytokine regulation of the trefoil factor family binding protein GKN2 (GDDR/TFIZ1/blottin) in human gastrointestinal epithelial cells.
Cell. Physiol. Biochem. 20: 193-204 (2007).
*
-
Bautista MV, Chen Y, Ivanova VS, Rahimi MK, Watson AM, Rose MC. IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.
J. Immunol. 183: 2159-2166 (2009).
-
Bax M, van Vliet SJ, Litjens M, García-Vallejo JJ, van Kooyk Y. Interaction of polysialic acid with CCL21 regulates the migratory capacity of human dendritic cells.
PLoS One 4: e6987 (2009).
*
-
Baxter SS, Carlson LA, Mayer AM, Hall ML, Fay MJ. Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5.
In Vitro Cell. Dev. Biol. Anim. 45: 264-274 (2009).
-
Bayat A, Watson JS, Stanley JK, Ferguson MW, Ollier WE. Genetic susceptibility to Dupuytren disease: association of Zf9 transcription factor gene.
Plast. Reconstr. Surg. 111: 2133-2139 (2003).
-
Bayle J, Fitch J, Jacobsen K, Kumar R, Lafyatis R, Lemaire R. Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis.
J. Invest. Dermatol. 128: 871-881 (2008).
*
-
Bayou N, M'rad R, Ahlem B, Bechir Helayem M, Chaabouni H. Autism: an overview of genetic aetiology.
Tunis. Med. 86: 573-578 (2008).
-
Bazan NG. Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations and Alzheimer's disease.
J. Lipid Res. 50: S400-S405 (2009).
*
-
Bazan NG. Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection.
Prostaglandins Leukot. Essent. Fatty Acids 81: 205-211 (2009).
*
-
Bazan NG. Lipid signaling in neural plasticity, brain repair, and neuroprotection.
Mol. Neurobiol. 32: 89-103 (2005).
-
Bazan NG. Neurotrophins induce neuroprotective signaling in the retinal pigment epithelial cell by activating the synthesis of the anti-inflammatory and anti-apoptotic neuroprotectin D1.
Adv. Exp. Med. Biol. 613: 39-44 (2008).
*
-
Bazhin AV, Schadendorf D, Owen RW, Zernii EY, Philippov PP, Eichmuller SB. Visible light modulates the expression of cancer-retina antigens.
Mol. Cancer Res. 6: 110-118 (2008).
*
-
Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, McIlrath J, Carr JM, Armit LJ, Clacher C, Malone L, Kollias G, Arthur JS. Generation and characterization of p38beta (MAPK11) gene-targeted mice.
Mol. Cell. Biol. 25: 10454-10464 (2005).
*
-
Beaumier CM, Harris LD, Goldstein S, Klatt NR, Whitted S, McGinty J, Apetrei C, Pandrea I, Hirsch VM, Brenchley JM. CD4 downregulation by memory CD4(+) T cells in vivo renders African green monkeys resistant to progressive SIVagm infection.
Nat. Med. 15: 879-885 (2009).
*
-
Beauquis J, Homo-Delarche F, Revsin Y, De Nicola AF, Saravia F. Brain alterations in autoimmune and pharmacological models of diabetes mellitus: focus on hypothalamic-pituitary-adrenocortical axis disturbances.
Neuroimmunomodulation 15: 61-67 (2008).
-
Becanovic K, Jagodic M, Sheng JR, Dahlman I, Aboul-Enein F, Wallstrom E, Olofsson P, Holmdahl R, Lassmann H, Olsson T. Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis.
J. Immunol. 176: 6055-6064 (2006).
*
-
Bechmann LP, Zahn D, Gieseler RK, Fingas CD, Marquitan G, Jochum C, Gerken G, Friedman SL, Canbay A. Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells.
Hepatol. Res. 39: 601-608 (2009).
*
-
Beck F, Plummer S, Senior PV, Byrne S, Green S, Brammar WJ. The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat.
Proc. Biol. Sci. 247: 83-87 (1992).
-
Beck GR Jr, Sullivan EC, Moran E, Zerler B. Relationship between alkaline phosphatase levels, osteopontin expression, and mineralization in differentiating MC3T3-E1 osteoblasts.
J. Cell. Biochem. 68: 269-280 (1998).
*
-
Beck IM, Berghe WV, Gerlo S, Bougarne N, Vermeulen L, De Bosscher K, Haegeman G. Glucocorticoids and mitogen- and stress-induced protein kinase 1 inhibitors: possible partners in the combat against inflammation.
Biochem. Pharmacol. 77: 1194-1205 (2009).
*
-
Beck IM, Vanden Berghe W, Vermeulen L, Bougarne N, Vander Cruyssen B, Haegeman G, De Bosscher K. Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition.
EMBO J. 27: 1682-1693 (2008).
*
-
Beck PL, Podolsky DK. Growth factors in inflammatory bowel disease.
Inflamm. Bowel Dis. 5: 44-60 (1999).
*
-
Becker C, Dornhoff H, Neufert C, Fantini MC, Wirtz S, Huebner S, Nikolaev A, Lehr HA, Murphy AJ, Valenzuela DM, Yancopoulos GD, Galle PR, Karow M, Neurath MF. Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis.
J. Immunol. 177: 2760-2764 (2006).
*
-
Becker C, Fantini MC, Wirtz S, Nikolaev A, Lehr HA, Galle PR, Rose-John S, Neurath MF. IL-6 signaling promotes tumor growth in colorectal cancer.
Cell Cycle 4: 217-220 (2005).
*
-
Becker C, Wirtz S, Blessing M, Pirhonen J, Strand D, Bechthold O, Frick J, Galle PR, Autenrieth I, Neurath MF. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells.
J. Clin. Invest. 112: 693-706 (2003).
*
-
Becker J, Delayre-Orthez C, Frossard N, Pons F. Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases?
Fundam. Clin. Pharmacol. 20: 429-447 (2006).
*
-
Becker KG. The common variants/multiple disease hypothesis of common complex genetic disorders.
Med. Hypotheses 62: 309-317 (2004).
-
Becker-Weimann S, Wolf J, Kramer A, Herzel H. A model of the mammalian circadian oscillator including the REV-ERBalpha module.
Genome Inform. 15: 3-12 (2004).
-
Becquemont L, Camus M, Kriaa F, Barbu V, Charpentier B, Jaillon P. Low levels of lymphocyte MDR1 gene expression during early renal transplantation in patients treated with tacrolimus.
Fundam. Clin. Pharmacol. 14: 225-229 (2000).
-
Becskei A, Grusby MJ. Contribution of IL-12R mediated feedback loop to Th1 cell differentiation.
FEBS Lett. 581: 5199-5206 (2007).
*
-
Bedrine-Ferran H, Le Meur N, Gicquel I, Le Cunff M, Soriano N, Guisle I, Mottier S, Monnier A, Teusan R, Fergelot P, Le Gall JY, Leger J, Mosser J. Transcriptome variations in human CaCo-2 cells: a model for enterocyte differentiation and its link to iron absorption.
Genomics 83: 772-789 (2004).
*
-
Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, Leehealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, et al. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases.
Proc. Natl. Acad. Sci. U.S.A. 103: 17414-17419 (2006).
*
-
Beetz S, Wesch D, Marischen L, Welte S, Oberg HH, Kabelitz D. Innate immune functions of human gammadelta T cells.
Immunobiology 213: 173-182 (2008).
-
Begni B, Amadori M, Ritelli M, Podavini D. Effects of IFN-alpha on the inflammatory response of swine leukocytes to bacterial endotoxin.
J. Interferon. Cytokine Res. 25: 202-208 (2005).
-
Begue B, Dumant C, Bambou JC, Beaulieu JF, Chamaillard M, Hugot JP, Goulet O, Schmitz J, Philpott DJ, Cerf-Bensussan N, Ruemmele FM. Microbial induction of CARD15 expression in intestinal epithelial cells via Toll-like receptor 5 triggers an antibacterial response loop.
J. Cell. Physiol. 209: 241-252 (2006).
*
-
Begum-Haque S, Sharma A, Kasper IR, Foureau DM, Mielcarz DW, Haque A, Kasper LH. Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitis.
J. Neuroimmunol. 204: 58-65 (2008).
-
Behera R, Kumar V, Lohite K, Karnik S, Kundu GC. Activation of JAK2/STAT3 signaling by osteopontin promotes tumor growth in human breast cancer cells.
Carcinogenesis Nov 19 [Epub ahead of print] (2009).
-
Behrendt M, Keiser M, Hoch M, Naim HY. Impaired trafficking and subcellular localization of a mutant lactase associated with congenital lactase deficiency.
Gastroenterology 136: 2295-2303 (2009).
*
-
Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response is associated with retinoid X receptor repression in rodent liver.
J. Biol. Chem. 275: 16390-16399 (2000).
*
-
Beilke LD, Aleksunes L, Holland R, Besselsen DG, Beger RD, Klaassen CD, Cherrington N. Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice.
Drug Metab. Dispos. 37: 1035-1045 (2009).
*
-
Beketic-Oreskovic L, Duran GE, Chen G, Dumontet C, Sikic BI. Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833.
J. Natl. Cancer Inst. 87: 1593-1602 (1995).
-
Bekpen C, Marques-Bonet T, Alkan C, Antonacci F, Leogrande MB, Ventura M, Kidd JM, Siswara P, Howard JC, Eichler EE. Death and resurrection of the human IRGM gene.
PLoS Genet. 5: e1000403 (2009).
*
-
Bektas M, Allende ML, Lee BG, Chen W, Amar MJ, Remaley AT, Saba JD, Proia RL. S1P lyase deficiency disrupts lipid homeostasis in liver.
J. Biol. Chem. Jan 24 [Epub ahead of print] (2010).
*
-
Bel Hadj Jrad B, Mahfouth W, Bouaouina N, Gabbouj S, Ahmed SB, Ltaief M, Jalbout M, Chouchane L. A polymorphism in FAS gene promoter associated with increased risk of nasopharyngeal carcinoma and correlated with anti-nuclear autoantibodies induction.
Cancer Lett. 233: 21-27 (2006).
*
-
Belaguli NS, Zhang M, Rigi M, Aftab M, Berger DH. Cooperation between GATA4 and TGF-beta signaling regulates intestinal epithelial gene expression.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1520-G1533 (2007).
*
-
Belakavadi M, Fondell JD. Role of the mediator complex in nuclear hormone receptor signaling.
Rev. Physiol. Biochem. Pharmacol. 156: 23-43 (2006).
-
Belcher CN, Vij N. Protein processing and inflammatory signaling in cystic fibrosis: challenges and therapeutic strategies.
Curr. Mol. Med. Jan 2 [Epub ahead of print] (2009).
-
Belinsky GS, Parke AL, Huang Q, Blanchard K, Jayadev S, Stoll R, Rothe M, Achenie LE, Gupta RR, Wu GY, Rosenberg DW. The contribution of methotrexate exposure and host factors on transcriptional variance in human liver.
Toxicol. Sci. 97: 582-594 (2007).
*
-
Belkind-Gerson J, Carreon-Rodriguez A, Contreras-Ochoa CO, Estrada-Mondaca S, Parra-Cabrera MS. Fatty acids and neurodevelopment.
J. Pediatr. Gastroenterol. Nutr. 47 Suppl. 1: S7-S9 (2008).
*
-
Bell AW, Michalopoulos GK. Phenobarbital regulates nuclear expression of HNF-4alpha in mouse and rat hepatocytes independent of CAR and PXR.
Hepatology 44: 186-194 (2006).
*
-
Bell LN, Theodorakis JL, Vuppalanchi R, Saxena R, Bemis KG, Wang M, Chalasani N. Serum proteomics and biomarker discovery across the spectrum of nonalcoholic fatty liver disease.
Hepatology 51: 111-120 (2010).
-
Bell MP, Svingen PA, Rahman MK, Xiong Y, Faubion WA. Forkhead box P3 regulates TLR10 expression in human T regulatory cells.
J. Immunol. 179: 1893-1900 (2007).
*
-
Bellanti JA, Sabra A, Zeligs BJ. Gastrointestinal immunopathology and food allergy.
Ann. Allergy Asthma Immunol. 93: S26-S32 (2004).
-
Bellemere G, Stamatas GN, Bruere V, Bertin C, Issachar N, Oddos T. Antiaging action of retinol: from molecular to clinical.
Skin Pharmacol. Physiol. 22: 200-209 (2009).
-
Bellemere G, Von Stetten O, Oddos T. Retinoic acid increases aquaporin 3 expression in normal human skin.
J. Invest. Dermatol. 128: 542-548 (2008).
*
-
Bellezza I, Tucci A, Minelli A. 2-Chloroadenosine and human prostate cancer cells.
Anticancer Agents Med. Chem. 8: 783-789 (2008).
-
Bellinger DL, Lorton D, Brouxhon S, Felten S, Felten DL. The significance of vasoactive intestinal polypeptide (VIP) in immunomodulation.
Adv. Neuroimmunol. 6: 5-27 (1996).
-
Bellodi-Privato M, Aubert D, Pichard V, Myara A, Trivin F, Ferry N. Successful gene therapy of the Gunn rat by in vivo neonatal hepatic gene transfer using murine oncoretroviral vectors.
Hepatology 42: 431-438 (2005).
*
-
Belogurov A Jr, Kozyr A, Ponomarenko N, Gabibov A. Catalytic antibodies: balancing between Dr. Jekyll and Mr. Hyde.
Bioessays 31: 1161-1171 (2009).
*
-
Beltowski J. Liver X receptors (LXR) as therapeutic targets in dyslipidemia.
Cardiovasc. Ther. 26: 297-316 (2008).
-
Beltowski J, Wojcicka G, Jamroz A. Peroxisome proliferator-activated receptors (PPAR) in pathophysiology of the circulatory system and prospective use of agonists of these receptors in therapy.
Postepy. Hig. Med. Dosw. 57: 199-217 (2003).
-
Belvederesi L, Bianchi F, Loretelli C, Gagliardini D, Galizia E, Bracci R, Rosati S, Bearzi I, Viel A, Cellerino R, Porfiri E. Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features.
Eur. J. Hum. Genet. 14: 853-859 (2006).
*
-
Belvisi MG, Hele DJ. Peroxisome proliferator-activated receptors as novel targets in lung disease.
Chest 134: 152-157 (2008).
*
-
Belvisi MG, Hele DJ, Birrell MA. Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation.
Eur. J. Pharmacol. 533: 101-109 (2006).
*
-
Belvisi MG, Mitchell JA. Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease.
Br. J. Pharmacol. 158: 994-1003 (2009).
-
Belyaeva OV, Johnson MP, Kedishvili NY. Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase.
J. Biol. Chem. 283: 20299-20308 (2008).
*
-
Bemeur C, Qu H, Desjardins P, Butterworth RF. IL-1 or TNF receptor gene deletion delays onset of encephalopathy and attenuates brain edema in experimental acute liver failure.
Neurochem. Int. Nov 17 [Epub ahead of print] (2009).
-
Ben Dhifallah I, Karray EF, Sassi F, Hamzaoui K. Intercellular adhesion molecule 1 K469E gene polymorphism is associated with presence of skin lesions in Tunisian Behcet's disease patients.
Tissue Antigens Nov 10 [Epub ahead of print] (2009).
*
-
Ben Gedalya T, Loeb V, Israeli E, Altschuler Y, Selkoe DJ, Sharon R. alpha-Synuclein and polyunsaturated fatty acids promote clathrin mediated endocytosis and synaptic vesicle recycling.
Traffic 10: 218-234 (2009).
*
-
Ben-Shushan E, Marshak S, Shoshkes M, Cerasi E, Melloul D. A pancreatic beta-cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta), HNF-1alpha, and SPs transcription factors.
J. Biol. Chem. 276: 17533-17540 (2001).
*
-
Benahmed F, Gross I, Gaunt SJ, Beck F, Jehan F, Domon-Dell C, Martin E, Kedinger M, Freund JN, Duluc I. Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene.
Gastroenterology 135: 1238-1247. e1-e3 (2008).
*
-
Benakanakere MR, Li Q, Eskan MA, Singh AV, Zhao J, Galicia JC, Stathopoulou P, Knudsen TB, Kinane DF. Modulation of TLR2 protein expression by a miR-105 in human oral keratinocytes.
J. Biol. Chem. 284: 23107-23115 (2009).
*
-
Benatar T, Cao MY, Lee Y, Lightfoot J, Feng N, Gu X, Lee V, Jin H, Wang M, Wright JA, Young AH. IL-17E, a proinflammatory cytokine, has antitumor efficacy against several tumor types in vivo.
Cancer Immunol. Immunother. Dec 14 [Epub ahead of print] (2009).
-
Benatti P, Peluso G, Nicolai R, Calvani M. Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties.
J. Am. Coll. Nutr. 23: 281-302 (2004).
*
-
Bendinelli P, Piccoletti R, Maroni P. Leptin rapidly activates PPARs in C2C12 muscle cells.
Biochem. Biophys. Res. Commun. 332: 719-725 (2005).
*
-
Benigni A, Zoja C, Tomasoni S, Campana M, Corna D, Zanchi C, Gagliardini E, Garofano E, Rottoli D, Ito T, Remuzzi G. Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone.
J. Am. Soc. Nephrol. 17: 1624-1632 (2006).
*
-
Benito-Martin A, Ucero A, Santamaría B, Lorz C, Kretzler M, Rastaldi M, Sanchez-Nino M, Sanz A, Izquierdo M, Ruiz Ortega M, Egido J, Ortiz A. Transcriptomics illustrate a deadly TRAIL to diabetic nephropathy.
Nefrologia 29: 13-19 (2009).
-
Benjamin JT, Smith RJ, Halloran BA, Day TJ, Kelly DR, Prince LS. FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation.
Am. J. Physiol. Lung Cell. Mol. Physiol. 292: L550-L558 (2007).
*
-
Benko S, Fantes JA, Amiel J, Kleinjan DJ, Thomas S, Ramsay J, Jamshidi N, Essafi A, Heaney S, Gordon CT, McBride D, Golzio C, Fisher M, Perry P, Abadie V, Ayuso C, Holder-Espinasse M, Kilpatrick N, Lees MM, Picard A, Temple IK, Thomas P, Vazquez MP, et al. Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence.
Nat. Genet. 41: 359-364 (2009).
*
-
Benlloch M, Ortega A, Ferrer P, Segarra R, Obrador E, Asensi M, Carretero J, Estrela JM. Acceleration of glutathione efflux and inhibition of gamma-glutamyl transpeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity.
J. Biol. Chem. 280: 6950-6959 (2005).
*
-
Bennett DJ, Carswell EL, Cooke AJ, Edwards AS, Nimz O. Design, structure activity relationships and X-ray co-crystallography of non-steroidal LXR agonists.
Curr. Med. Chem. 15: 195-209 (2008).
-
Bennett ST, Wilson AJ, Cucca F, Nerup J, Pociot F, McKinney PA, Barnett AH, Bain SC, Todd JA. IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus.
J. Autoimmun. 9: 415-421 (1996).
-
Bennetts BH, Teutsch SM, Buhler MM, Heard RN, Stewart GJ. The CCR5 deletion mutation fails to protect against multiple sclerosis.
Hum. Immunol. 58: 52-59 (1997).
-
Bennouna S, Sukhumavasi W, Denkers EY. Toxoplasma gondii inhibits Toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils.
Infect. Immun. 74: 4274-4281 (2006).
*
-
Benoit LA, Holtzman MJ. New immune pathways from chronic post-viral lung disease.
Ann. N. Y. Acad. Sci. 1183: 195-210 (2010).
*
-
Benoit S, Toksoy A, Brocker EB, Gillitzer R, Goebeler M. Treatment of recalcitrant pustular psoriasis with infliximab: effective reduction of chemokine expression.
Br. J. Dermatol. 150: 1009-1012 (2004).
*
-
Bensalem N, Ventura AP, Vallee B, Lipecka J, Tondelier D, Davezac N, Dos Santos A, Perretti M, Fajac A, Sermet-Gaudelus I, Renouil M, Lesure JF, Halgand F, Laprevote O, Edelman A. Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients.
Mol. Cell. Proteomics 4: 1591-1601 (2005).
*
-
Benschop R, Wei T, Na S. Tumor necrosis factor receptor superfamily member 21: TNFR-related death receptor-6, DR6.
Adv. Exp. Med. Biol. 647: 186-194 (2009).
*
-
Bensi G, Raugei G, Klefenz H, Cortese R. Structure and expression of the human haptoglobin locus.
EMBO J. 4: 119-126 (1985).
*
-
Bensing S, Fetissov SO, Mulder J, Perheentupa J, Gustafsson J, Husebye ES, Oscarson M, Ekwall O, Crock PA, Hokfelt T, Hulting AL, Kampe O. Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1.
Proc. Natl. Acad. Sci. U.S.A. 104: 949-954 (2007).
*
-
Benson EB, Strober W. Regulation of IgA secretion by T cell clones derived from the human gastrointestinal tract.
J. Immunol. 140: 1874-1882 (1988).
-
Benson JM, Pokorny AJ, Rhule-Smith A, Wenner CA, Kandhi V, Cech NB, Shepherd DM. Echinacea pupurea extracts modulate murine dendritic cell fate and function.
Food Chem. Toxicol. Feb 8 [Epub ahead of print] (2010).
*
-
Benson M, Carlsson L, Guillot G, Jernas M, Langston MA, Rudemo M, Andersson B. A network-based analysis of allergen-challenged CD4+ T cells from patients with allergic rhinitis.
Genes Immun. 7: 514-521 (2006).
*
-
Benten D, Kumaran V, Joseph B, Schattenberg J, Popov Y, Schuppan D, Gupta S. Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat.
Hepatology 42: 1072-1081 (2005).
*
-
Bentrem DJ, Joehl RJ. Pancreas: healing response in critical illness.
Crit. Care Med. 31: S582-S589 (2003).
-
Benvenisty N, Reshef L. Regulation of tissue- and development-specific gene expression in the liver.
Biol. Neonate 59: 181-189 (1991).
-
Benyon RC, Arthur MJ. Extracellular matrix degradation and the role of hepatic stellate cells.
Semin. Liver Dis. 21: 373-384 (2001).
-
Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJ. Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver.
Gastroenterology 110: 821-831 (1996).
*
-
Berard AM, Dumon MF, Darmon M. Dietary fish oil up-regulates cholesterol 7alpha-hydroxylase mRNA in mouse liver leading to an increase in bile acid and cholesterol excretion.
FEBS Lett. 559: 125-128 (2004).
*
-
Berard JL, Wolak K, Fournier S, David S. Characterization of relapsing-remitting and chronic forms of experimental autoimmune encephalomyelitis in C57BL/6 mice.
Glia Sep 24 [Epub ahead of print] (2009).
*
-
Berasain C, Garcia-Trevijano ER, Castillo J, Erroba E, Lee DC, Prieto J, Avila MA. Amphiregulin: an early trigger of liver regeneration in mice.
Gastroenterology 128: 424-432 (2005).
*
-
Beraza N, Marques JM, Martinez-Anso E, Iniguez M, Prieto J, Bustos M. Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration.
Hepatology 41: 460-469 (2005).
*
-
Berberat PO, A-Rahim YI, Yamashita K, Warny MM, Csizmadia E, Robson SC, Bach FH. Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis.
Inflamm. Bowel Dis. 11: 350-359 (2005).
*
-
Bercher M, Hanson B, van Staden C, Wu K, Ng GY, Lee PH. Agonists of the orphan human G2A receptor identified from inducible G2A expression and beta-lactamase reporter screen.
Assay Drug Dev. Technol. 7: 133-142 (2009).
-
Berchtold CM, Wu ZH, Huang TT, Miyamoto S. Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli.
Mol. Cell. Biol. 27: 497-509 (2007).
*
-
Berchtold LA, Larsen CM, Vaag A, Faulenbach M, Workman CT, Kruhøffer M, Donath M, Mandrup-Poulsen T. IL-1 receptor antagonism and muscle gene expression in patients with type 2 diabetes.
Eur. Cytokine Netw. 20: 81-87 (2009).
-
Berdal A. Vitamin D: biosynthesis, metabolism and mechanism of action at the cellular level.
J. Biol. Buccale. 20: 71-83 (1992).
-
Berg L, Koch T, Heerkens T, Bessonov K, Thomsen P, Betts D. Chondrogenic potential of mesenchymal stromal cells derived from equine bone marrow and umbilical cord blood.
Vet. Comp. Orthop. Traumatol. 22: 363-370 (2009).
-
Berg PA, Klein R, Rocken M. Cytokines in primary biliary cirrhosis.
Semin. Liver Dis. 17: 115-123 (1997).
-
Bergamaschi G. Two novel mutations, L490R and V561X, in transferrin receptor 2 in Japanese patients with hemochromatosis.
Haematologica 90: 289A (2005).
*
-
Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD. Glucocorticoids and tumor necrosis factor-alpha synergize to induce colonic sodium absorption by the epithelial sodium channel.
Gastroenterology 136: 933-942.e2 (2009).
*
-
Bergasa NV. The pruritus of cholestasis.
J. Hepatol. 43: 1078-1088 (2005).
*
-
Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ. Primary biliary cirrhosis: report of a focus study group.
Hepatology 40: 1013-1020 (2004).
*
-
Bergen AA, Plomp AS, Gorgels TG, de Jong PT. From gene to disease; pseudoxanthoma elasticum and the ABCC6 gene.
Ned. Tijdschr. Geneeskd. 148: 1586-1589 (2004).
-
Berger A, Mutch DM, German JB, Roberts MA. Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression.
Lipids Health Dis. 1: 2 (2002).
*
-
Berger A, Mutch DM, German JB, Roberts MA. Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression.
Genome Biol. 3: PREPRINT0004 (2002).
*
-
Berger J, Moller DE. The mechanisms of action of PPARs.
Annu. Rev. Med. 53: 409-435 (2002).
*
-
Berger J, Wagner JA. Physiological and therapeutic roles of peroxisome proliferator-activated receptors.
Diabetes Technol. Ther. 4: 163-174 (2002).
-
Berghofer-Hochheimer Y, Zurek C, Langer G, Munder T. Expression of the vitamin D and the retinoid X receptors in Saccharomyces cerevisiae: alternative in vivo models for ligand-induced transactivation.
J. Cell. Biochem. 66: 184-196 (1997).
*
-
Bergholdt R, Karlsen AE, Hagedorn PH, Aalund M, Nielsen JH, Kruhoffer M, Orntoft T, Wang H, Wollheim CB, Nerup J, Pociot F. Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets.
Genes Immun. 8: 232-238 (2007).
*
-
Bergholdt R, Taxvig C, Eising S, Nerup J, Pociot F. CBLB variants in type 1 diabetes and their genetic interaction with CTLA4.
J. Leukoc. 77: 579-585 (2005).
*
-
Bergmann F, Breinig M, Hopfner M, Rieker RJ, Fischer L, Kohler C, Esposito I, Kleeff J, Herpel E, Ehemann V, Friess H, Schirmacher P, Kern MA. Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors?
Am. J. Gastroenterol. 104: 171-181 (2009).
*
-
Bergmann H, Rogoll D, Scheppach W, Melcher R, Richling E. The Ussing type chamber model to study the intestinal transport and modulation of specific tight-junction genes using a colonic cell line.
Mol. Nutr. Food Res. 53: 1211-1225 (2009).
*
-
Bergtold A, Gavhane A, D'Agati V, Madaio M, Clynes R. FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis.
J. Immunol. 177: 7287-7295 (2006).
*
-
Beringer PM, Kriengkauykiat J, Zhang X, Hidayat L, Liu S, Louie S, Synold T, Burckart GJ, Rao PA, Shapiro B, Gill M. Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis.
Pharmacotherapy 28: 883-894 (2008).
-
Beriou G, Costantino CM, Ashley CW, Yang L, Kuchroo VK, Baecher-Allan C, Hafler DA. IL-17 producing human peripheral regulatory T cells retain suppressive function.
Blood 113: 4240-4249 (2009).
*
-
Berkowitz CM, Shen CS, Bilir BM, Guibert E, Gumucio JJ. Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo.
Hepatology 21: 1658-1667 (1995).
-
Berlec A, Strukelj B. Novel applications of recombinant lactic acid bacteria in therapy and in metabolic engineering.
Recent Pat. Biotechnol. 3: 77-87 (2009).
-
Berlin AL, Paller AS, Chan LS. Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology.
J. Am. Acad. Dermatol. 47: 169-187 (2002).
-
Bermudez B, Lopez S, Pacheco YM, Villar J, Muriana FJ, Hoheisel JD, Bauer A, Abia R. The influence of postprandial triglyceride-rich lipoproteins on lipid-mediated gene expression in smooth muscle cells of the human coronary artery.
Cardiovasc. Res. 79: 294-303 (2008).
*
-
Bermudo R, Abia D, Ferrer B, Nayach I, Benguria A, Zaballos A, Del Rey J, Miro R, Campo E, Martinez-A C, Ortiz AR, Fernandez PL, Thomson TM. Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer.
BMC Cancer 8: 315 (2008).
*
-
Bernales I, Fullaondo A, Marin-Vidalled MJ, Ucar E, Martinez-Taboada V, Lopez-Hoyos M, Zubiaga AM. Innate immune response gene expression profiles characterize primary antiphospholipid syndrome.
Genes Immun. 9: 38-46 (2008).
*
-
Bernard MP, Phipp RP. Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human B-lymphocyte differentiation.
Immunology 129: 87-96 (2010).
*
-
Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT. Toll-like receptors: insights into their possible role in the pathogeneis of Lyme neuroborreliosis.
Infect. Immun. 76: 4385-4395 (2008).
*
-
Bernardo AS, Hay CW, Docherty K. Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell.
Mol. Cell. Endocrinol. 294: 1-9 (2008).
-
Bernasconi P, Barberis M, Baggi F, Passerini L, Cannone M, Arnoldi E, Novellino L, Cornelio F, Mantegazza R. Increased Toll-like receptor 4 expression in thymus of myasthenic patients with thymitis and thymic involution.
Am. J. Pathol. 167: 129-139 (2005).
*
-
Bernatoniene J, Zhang Q, Dogan S, Mitchell TJ, Paton JC, Finn A. Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by Toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases.
J. Infect. Dis. 198: 1823-1833 (2008).
*
-
Berndt U, Philipsen L, Bartsch S, Wiedenmann B, Baumgart DC, Hammerle M, Sturm A. Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer.
Cancer Res. 68: 880-888 (2008).
*
-
Bernotas RC, Singhaus RR, Kaufman DH, Ullrich J, Fletcher H 3rd, Quinet E, Nambi P, Unwalla R, Wilhelmsson A, Goos-Nilsson A, Farnegardh M, Wrobel J. Biarylether amide quinolines as liver X receptor agonists.
Bioorg. Med. Chem. 17: 1663-1670 (2009).
*
-
Bernstein H, Holubec H, Bernstein C, Ignatenko N, Gerner E, Dvorak K, Besselsen D, Ramsey L, Dall'Agnol M, Blohm-Mangone KA, Padilla-Torres J, Cui H, Garewal H, Payne CM. Unique dietary-related mouse model of colitis.
Inflamm. Bowel Dis. 12: 278-293 (2006).
*
-
Bernstein H, Holubec H, Bernstein C, Ignatenko NA, Gerner E, Dvorak K, Besselsen D, Blohm-Mangone KA, Padilla-Torres J, Dvorakova B, Garewal H, Payne CM. Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles.
Dig. Dis. Sci. 52: 628-642 (2007).
*
-
Bernstein H, Payne CM, Kunke K, Crowley-Weber CL, Waltmire CN, Dvorakova K, Holubec H, Bernstein C, Vaillancourt RR, Raynes DA, Guerriero V, Garewal H. A proteomic study of resistance to deoxycholate-induced apoptosis.
Carcinogenesis 25: 681-692 (2004).
*
-
Berrebi D, Maudinas R, Hugot JP, Chamaillard M, Chareyre F, De Lagausie P, Yang C, Desreumaux P, Giovannini M, Cezard JP, Zouali H, Emilie D, Peuchmaur M. Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon.
Gut 52: 840-846 (2003).
*
-
Berrih-Aknin S. Myasthenia gravis, a model of organ-specific autoimmune disease.
J. Autoimmun. 8: 139-143 (1995).
-
Berry DC, Noy N. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor.
Mol. Cell. Biol. 29: 3286-3296 (2009).
*
-
Berstad AE, Brandtzaeg P. Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract.
Gut 42: 522-529 (1998).
*
-
Bertagnolli MM. Cyclooxygenase-2 as a target for prevention of colorectal cancer.
Curr. Oncol. Rep. 1: 173-178 (1999).
-
Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH. The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis.
Exp. Cell Res. 313: 1696-1709 (2007).
*
-
Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Backman M, Ohlsson R, Postlind H, Blomquist P, Berkenstam A. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction.
Proc. Natl. Acad. Sci. U.S.A. 95: 12208-12213 (1998).
*
-
Bertolini A, Ottani A, Sandrini M. Selective COX-2 inhibitors and dual acting anti-inflammatory drugs: critical remarks.
Curr. Med. Chem. 9: 1033-1043 (2002).
-
Bertolino P, Bowen DG, Zen M, Holz L, Davis T, McCaughan GW. Hepatocytes as targets of autoreactivity.
Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, p. 33 (2004). *
-
Bertolino P, Holz LE. Toll-like receptor-3 and the regulation of intrahepatic immunity: implications for interferon-alpha therapy.
Hepatology 45: 250-251 (2007).
*
-
Bertram JS, Vine AL. Cancer prevention by retinoids and carotenoids: independent action on a common target.
Biochim. Biophys. Acta 1740: 170-178 (2005).
*
-
Bertrand-Philippe M, Ruddell RG, Arthur MJ, Thomas J, Mungalsingh N, Mann DA. Regulation of tissue inhibitor of metalloproteinase-1 gene transcription by RUNX1 and RUNX2.
J. Biol. Chem. 279: 24530-24539 (2004).
*
-
Bertsias GK, Nakou M, Choulaki C, Raptopoulou A, Papadimitraki E, Goulielmos G, Kritikos H, Sidiropoulos P, Tzardi M, Kardassis D, Mamalaki C, Boumpas DT. Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus.
Arthritis Rheum. 60: 207-218 (2009).
*
-
Bertucci F, Salas S, Eysteries S, Nasser V, Finetti P, Ginestier C, Charafe-Jauffret E, Loriod B, Bachelart L, Montfort J, Victorero G, Viret F, Ollendorff V, Fert V, Giovaninni M, Delpero JR, Nguyen C, Viens P, Monges G, Birnbaum D, Houlgatte R. Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters.
Oncogene 23: 1377-1391 (2004).
*
-
Besancon F, Przewlocki G, Baro I, Hongre AS, Escande D, Edelman A. Interferon-gamma downregulates CFTR gene expression in epithelial cells.
Am. J. Physiol. 267: C1398-C1404 (1994).
-
Besnard P, Landrier JF, Grober J, Niot I. Is the ileal bile acid-binding protein (I-BABP) gene involved in cholesterol homeostasis?
Med. Sci. (Paris) 20: 73-77 (2004).
-
Besnard S, Silvestre JS, Duriez M, Bakouche J, Lemaigre-Dubreuil Y, Mariani J, Levy BI, Tedgui A. Increased ischemia-induced angiogenesis in the staggerer mouse, a mutant of the nuclear receptor Roralpha.
Circ. Res. 89: 1209-1215 (2001).
*
-
Besnard V, Wert SE, Hull WM, Whitsett JA. Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.
Gene Expr. Patterns 5: 193-208 (2004).
*
-
Besnard V, Xu Y, Whitsett JA. Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression.
Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L1395-L405 (2007).
*
-
Best I, Lopez G, Verdonck K, Gonzalez E, Tipismana M, Gotuzzo E, Vanham G, Clark D. IFN-gamma production in response to Tax 161-233, and frequency of CD4+ Foxp3+ and Lin HLA-DRhigh CD123+ cells, discriminate HAM/TSP patients from asymptomatic HTLV-1-carriers in a Peruvian population.
Immunology 128: e777-e786 (2009).
-
Betser-Cohen G, Katz G, Gonen-Gross T, Stern N, Arnon TI, Achdout H, Gazit R, Mandelboim O. Reduced KIR2DL1 recognition of MHC class I molecules presenting phosphorylated peptides.
J. Immunol. 176: 6762-6769 (2006).
*
-
Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappaB to repress cytokine gene expression and effector functions of T helper cells.
Proc. Natl. Acad. Sci. U.S.A. 102: 5138-5143 (2005).
*
-
Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity.
Nat. Immunol. 8: 345-350 (2007).
*
-
Bettencourt R, Tanji T, Yagi Y, Ip YT. Toll and Toll-9 in Drosophila innate immune response.
J. Endotoxin Res. 10: 261-268 (2004).
*
-
Bettoun DJ, Burris TP, Houck KA, Buck DW 2nd, Stayrook KR, Khalifa B, Lu J, Chin WW, Nagpal S. Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation.
Mol. Endocrinol. 17: 2320-2328 (2003).
*
-
Betz S, Kaser A, Nagaishi T, Yoshida M, Hussain M, vander Lugt B, Exley M, Blumberg RS. Lipids and IBD: microsomal triglyceride transfer protein - the new dimension?
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 23 (2005). *
-
Beuers U, Kullak-Ublick GA, Pusl T, Rauws ER, Rust C. Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators?
Clin. Rev. Allergy Immunol. 36: 52-61 (2009).
*
-
Beveridge NJ, Tooney PA, Carroll AP, Tran N, Cairns MJ. Down-regulation of miR-17 family expression in response to retinoic acid induced neuronal differentiation.
Cell Signal. 21: 1837-1845 (2009).
*
-
Bevins CL. Defensins and other antibacterial mediators.
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 45 (2005). *
-
Bevins CL. Paneth cell defensins: key effector molecules of innate immunity.
Biochem. Soc. Trans. 34: 263-266 (2006).
*
-
Bevins CL. The role of gut flora and innate immunity in pathogenesis of inflammatory bowel disease.
Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 58. September 12 - 13 (2003). *
-
Bewry NN, Bolick SC, Wright KL, Harton JA. GTP-dependent recruitment of CIITA to the class II major histocompatibility complex promoter.
J. Biol. Chem. 282: 26178-26184 (2007).
*
-
Beyea MM, Heslop CL, Sawyez CG, Edwards JY, Markle JG, Hegele RA, Huff MW. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1 and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol.
J. Biol. Chem. 282: 5207-5216 (2007).
*
-
Beyer TP, Chen Y, Porter RK, Lu D, Schmidt RJ, Mantlo NB, Konrad RJ, Cao G. Peroxisome proliferator-activated receptor alpha agonists regulate cholesterol ester transfer protein.
Lipids 43: 611-618 (2008).
-
Bezbradica JS, Medzhitov R. Integration of cytokine and heterologous receptor signaling pathways.
Nat. Immunol. 10: 333-339 (2009).
*
-
Bhadhprasit W, Sakuma T, Hatakeyama N, Fuwa M, Kitajima K, Nemoto N. Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 female-predominant expression by glucocorticoid hormone.
Drug Metab. Dispos. 35: 1880-1885 (2007).
*
-
Bhagat G, Naiyer AJ, Shah JG, Harper J, Jabri B, Wang TC, Green PH, Manavalan JS. Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease.
J. Clin. Invest. 118: 281-293 (2008).
*
-
Bhalla S, Ozalp C, Fang S, Xiang L, Kemper JK. Ligand-activated PXR interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha: functional implications in hepatic cholesterol and glucose metabolism.
J. Biol. Chem. 279: 45139-45147 (2004).
*
-
Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription.
Mol. Immunol. 45: 2214-2224 (2008).
*
-
Bhat MK, Ashizawa K, Cheng SY. Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor.
Proc. Natl. Acad. Sci. U.S.A. 91: 7927-7931 (1994).
*
-
Bhat R, Bresnick E. Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor.
J. Biol. Chem. 272: 21221-21226 (1997).
*
-
Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3).
J. Hum. Genet. 51: 575-580 (2006).
*
-
Bhattacharya S, Mathew G, Jayne DG, Pelengaris S, Khan M. 15-Lipoxygenase-1 in colorectal cancer: a review.
Tumour Biol. 30: 185-199 (2009).
-
Bhattacharyya Majumdar S, Dey R, Majumder N, Bhattacharjee S, Majumdar S. A novel approach to regulate experimental visceral leishmaniasis in murine macrophages using CCR5 siRNA.
Scand. J. Immunol. 67: 345-353 (2008).
*
-
Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, Benz CC. Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells.
Oncogene 27: 5643-5647 (2008).
*
-
Bhavsar MD, Amiji MM. Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease.
Gene Ther. 15: 1200-1209 (2008).
-
Bhavsar MD, Amiji MM. Polymeric nano- and microparticle technologies for oral gene delivery.
Expert Opin. Drug Deliv. 4: 197-213 (2007).
-
Bhavsar PK, Sukkar MB, Khorasani N, Lee KY, Chung KF. Glucocorticoid suppression of CX3CL1 (fractalkine) by reduced gene promoter recruitment of NF-kappaB.
FASEB J. 22: 1807-1816 (2008).
*
-
Bhavsar SK, Singh S, Giri S, Jain MR, Santani DD. Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression.
J. Ethnopharmacol. 124: 426-433 (2009).
-
Bhide MR, Mucha R, Mikula I Jr, Kisova L, Skrabana R, Novak M, Mikula I Sr. Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection.
BMC Genet. 10: 21 (2009).
*
-
Bhoj EJ, Romeo S, Baroni MG, Bartov G, Schultz RA, Zinn AR. MODY-like diabetes associated with an apparently balanced translocation: possible involvement of MPP7 gene and cell polarity in the pathogenesis of diabetes.
Mol. Cytogenet. 2:5 (2009).
*
-
Bhojani MS, Hamstra DA, Chang DC, Coppola JM, Khan AP, Reddy GR, Ross BD, Rehemtulla A. Imaging of proteolytic activity using a conditional cell surface receptor.
Mol. Imaging 5: 129-137 (2006).
-
Bhura-Bandali FN, Suh M, Man SF, Clandinin MT. The deltaF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells.
J. Nutr. 130: 2870-2875 (2000).
*
-
Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB. Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation.
Clin. Cancer Res. 13: 3024-3032 (2007).
*
-
Bi Y, Sun WP, Chen X, Li M, Liang H, Cai MY, Zhu YH, He XY, Xu F, Weng JP. Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats.
Acta Diabetol. 45: 167-178 (2008).
-
Bialecka M, Hnatyszyn G, Bielicka-Cymerman J, Drozdzik M. The effect of MDR1 gene polymorphism in the pathogenesis and the treatment of drug-resistant epilepsy.
Neurol. Neurochir. Pol. 39: 476-481 (2005).
-
Bian GX, Miao H, Qiu L, Cao DM, Guo BY. Profiling of differentially expressed chemotactic-related genes in MCP-1 treated macrophage cell line using human cDNA arrays.
World J. Gastroenterol. 11: 2508-2512 (2005).
*
-
Bian ZM, Elner SG, Elner VM. Regulated expression of truncated short variants of caspase-12 mRNA in human retinal pigment epithelial cells suggests their immunomodulating role.
Invest. Ophthalmol. Vis. Sci. 49: 5593-5601 (2008).
*
-
Bianchi MG, Gazzola GC, Cagnin S, Kagechika H, Bussolati O. The ATRA-dependent overexpression of the glutamate transporter EAAC1 requires RARbeta induction.
Biochim. Biophys. Acta 1788: 1861-1868 (2009).
*
-
Bianchi MG, Gazzola GC, Tognazzi L, Bussolati O. C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1).
Neuroscience 151: 1042-1052 (2008).
-
Bianchi T, Pincus LB, Wurbel MA, Rich BE, Kupper TS, Fuhlbrigge RC, Boes M. Maintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice.
J. Immunol. 182: 4665-4674 (2009).
-
Biancone L, Palmieri G, Lombardi A, Vavassori P, Monteleone I, Del Vecchio Blanco G, Colantoni A, Spagnoli L, Tonelli F, Pallone F. Cytoskeletal proteins and resident flora.
Dig. Liver Dis. 34 Suppl. 2: S34-S36 (2002).
-
Biasi F, Mascia C, Poli G. TGFbeta1 expression in colonic mucosa: modulation by dietary lipids.
Genes Nutr. 2: 233-243 (2007).
*
-
Bickenbach KA, Veerapong J, Shao MY, Mauceri HJ, Posner MC, Kron SJ, Weichselbaum RR. Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy.
Cancer Gene Ther. 15: 133-139 (2008).
-
Bickston SJ, Comerford LW, Cominelli F. Future therapies for inflammatory bowel disease.
Curr. Gastroenterol. Rep. 5: 518-523 (2003).
-
Bienkowska J, Dagin G, Batliwalla F, Allaire N, Roubenoff R, Gregersen P, Carulli J. Convergent random forest predictor: methodology for predicting drug response from genome-scale data applied to anti-TNF response.
Genomics 94: 423-432 (2009).
*
-
Bienvenu T. Cystic fibrosis: relationship between genotype and phenotype.
Arch. Pediatr. 10 Suppl. 2: 318s-324s (2003).
-
Biernacka JM, Sun L, Bull SB. Simultaneous localization of two linked disease susceptibility genes.
Genet. Epidemiol. 28: 33-47 (2004).
*
-
Biesalski HK, Tinz J. Nutritargeting.
Adv. Food Nutr. Res. 54: 179-217 (2008).
-
Bigger B, Coutelle C. Perspectives on gene therapy for cystic fibrosis airway disease.
BioDrugs 15: 615-634 (2001).
-
Bighetti EJ, Patricio PR, Casquero AC, Berti JA, Oliveira HC. Ciprofibrate increases cholesteryl ester transfer protein gene expression and the indirect reverse cholesterol transport to the liver.
Lipids Health Dis. 8: 50 (2009).
*
-
Bigliardi PL, Stammer H, Jost G, Rufli T, Buchner S, Bigliardi-Qi M. Treatment of pruritus with topically applied opiate receptor antagonist.
J. Am. Acad. Dermatol. 56: 979-988 (2007).
-
Bihl F, Salez L, Beaubier M, Torres D, Lariviere L, Laroche L, Benedetto A, Martel D, Lapointe JM, Ryffel B, Malo D. Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice.
J. Immunol. 170: 6141-6150 (2003).
*
-
Bijl M, Reefman E, Horst G, Limburg PC, Kallenberg CG. Reduced uptake of apoptotic cells by macrophages in systemic lupus erythematosus (SLE): correlates with decreased serum levels of complement.
Ann. Rheum. Dis. 65: 57-63 (2006).
*
-
Bijl N, Sokolovic M, Vrins C, Langeveld M, Moerland PD, Ottenhoff R, van Roomen CP, Claessen N, Boot RG, Aten J, Groen AK, Aerts JM, van Eijk M. Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice.
Hepatology 50: 1431-1441 (2009).
-
Bikle D, Teichert A, Hawker N, Xie Z, Oda Y. Sequential regulation of keratinocyte differentiation by 1,25(OH)(2)D(3), VDR, and its coregulators.
J. Steroid Biochem. Mol. Biol. 103: 396-404 (2007).
-
Bikle DD, Elalieh H, Chang S, Xie Z, Sundberg JP. Development and progression of alopecia in the vitamin D receptor null mouse.
J. Cell. Physiol. 207: 340-353 (2006).
*
-
Bilate AM, Salemi VM, Ramires FJ, de Brito T, Russo M, Fonseca SG, Fae KC, Martins DG, Silva AM, Mady C, Kalil J, Cunha-Neto E. TNF blockade aggravates experimental chronic Chagas disease cardiomyopathy.
Microbes Infect. 9: 1104-1113 (2007).
*
-
Bilban M, Haslinger P, Prast J, Klinglmuller F, Woelfel T, Haider S, Sachs A, Otterbein LE, Desoye G, Hiden U, Wagner O, Knofler M. Identification of novel trophoblast invasion-related genes: heme oxygenase-1 controls motility via PPARgamma.
Endocrinology 150: 1000-1013 (2009).
*
-
Bilgic H, Ytterberg SR, Amin S, McNallan KT, Wilson JC, Koeuth T, Ellingson S, Newman B, Bauer JW, Peterson EJ, Baechler EC, Reed AM. Interleukin-6 and type I interferon-regulated genes and chemokines mark disease activity in dermatomyositis.
Arthritis Rheum. 60: 3436-3446 (2009).
*
-
Bilitewski U. DNA microarrays: an introduction to the technology.
Methods Mol. Biol. 509: 1-14 (2009).
*
-
Bility MT, Devlin-Durante MK, Blazanin N, Glick AB, Ward JM, Kang BH, Kennett MJ, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits chemically-induced skin tumorigenesis.
Carcinogenesis 29: 2406-2414 (2008).
*
-
Bility MT, Zhu B, Kang BH, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) and inhibition of cyclooxygenase 2 (COX2) enhances inhibition of skin tumorigenesis.
Toxicol. Sci. 113: 27-36 (2010).
*
-
Billaut-Laden I, Allorge D, Crunelle-Thibaut A, Rat E, Cauffiez C, Chevalier D, Houdret N, Lo-Guidice JM, Broly F. Evidence for a functional genetic polymorphism of the human thiosulfate sulfurtransferase (Rhodanese), a cyanide and H(2)S detoxification enzyme.
Toxicology 225: 1-11 (2006).
*
-
Billaut-Laden I, Rat E, Allorge D, Crunelle-Thibaut A, Cauffiez C, Chevalier D, Lo-Guidice JM, Broly F. Evidence for a functional genetic polymorphism of the human mercaptopyruvate sulfurtransferase (MPST), a cyanide detoxification enzyme.
Toxicol. Lett. 165: 101-111 (2006).
-
Billerey-Larmonier C, Uno JK, Larmonier N, Midura AJ, Timmermann B, Ghishan FK, Kiela PR. Protective effects of dietary curcumin in mouse model of chemically induced colitis are strain dependent.
Inflamm. Bowel Dis. 14: 780-793 (2008).
*
-
Billiet L, Furman C, Larigauderie G, Copin C, Page S, Fruchart JC, Brand K, Rouis M. Enhanced VDUP-1 gene expression by PPARgamma agonist induces apoptosis in human macrophage.
J. Cell. Physiol. 214: 183-191 (2008).
*
-
Bilz S, Samuel V, Morino K, Savage D, Choi CS, Shulman GI. Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters.
Am. J. Physiol. Endocrinol. Metab. 290: E716-E722 (2006).
*
-
Bingemann SC, Konrad TA, Wieser R. Zinc finger transcription factor ecotropic viral integration site 1 is induced by all-trans retinoic acid (ATRA) and acts as a dual modulator of the ATRA response.
FEBS J. Oct 16 [Epub ahead of print] (2009).
*
-
Bingle CD, Craven CJ. PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx.
Hum. Mol. Genet. 11: 937-943 (2002).
*
-
Bingle L, Barnes FA, Cross SS, Rassl D, Wallace WA, Campos MA, Bingle CD. Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis.
Respir. Res. 8: 79 (2007).
*
-
Binion DG, Kugathasan S, Dwinell MB. Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup.
Am. J. Gastroenterol. 101: 107-109 (2006).
*
-
Biola A, Pallardy M. Mode of action of glucocorticoids.
Presse. Med. 29: 215-223 (2000).
-
Bioley G, Guillaume P, Luescher I, Yeh A, Dupont B, Bhardwaj N, Mears G, Old LJ, Valmori D, Ayyoub M. HLA class I-associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine.
Clin. Cancer Res. 15: 299-306 (2009).
*
-
Bionaz M, Baumrucker CR, Shirk E, Vanden Heuvel JP, Block E, Varga GA. Characterization of Madin-Darby bovine kidney cell line for peroxisome proliferator-activated receptors: temporal response and sensitivity to fatty acids.
J. Dairy Sci. 91: 2808-2813 (2008).
-
Biondo M, Field J, Toh BH, Alderuccio F. Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis.
J. Pathol. 209: 384-391 (2006).
*
-
Biosse-Duplan M, Baroukh B, Dy M, de Vernejoul MC, Saffar JL. Histamine promotes osteoclastogenesis through the differential expression of histamine receptors on osteoclasts and osteoblasts.
Am. J. Pathol. 174: 1426-1434 (2009).
*
-
Birch D, Knight GE, Boulos PB, Burnstock G. Analysis of innervation of human mesenteric vessels in non-inflamed and inflamed bowel - a confocal and functional study.
Neurogastroenterol. Motil. 20: 660-670 (2008).
-
Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, Beauplet A, Robillard N, Semana G. Suppressive properties of human CD4(+)CD25(+) regulatory T cells are dependent on CTLA-4 expression.
Eur. J. Immunol. 34: 3485-3496 (2004).
*
-
Birkenkamp-Demtroder K, Olesen SH, Sorensen FB, Laurberg S, Laiho P, Aaltonen LA, Orntoft TF. Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid.
Gut 54: 374-384 (2005).
*
-
Birmachu W, Gleason RM, Bulbulian BJ, Riter CL, Vasilakos JP, Lipson KE, Nikolsky Y. Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists.
BMC Immunol. 8: 26 (2007).
*
-
Birnbaum G, Kotilinek L. Heat shock or stress proteins and their role as autoantigens in multiple sclerosis.
Ann. N. Y. Acad. Sci. 835: 157-167 (1997).
*
-
Birnbaum G, Kotilinek L. Immunity to heat shock proteins and neurological disorders of women.
Infect. Dis. Obstet. Gynecol. 7: 39-48 (1999).
-
Biro T, Toth BI, Marincsak R, Dobrosi N, Geczy T, Paus R. TRP channels as novel players in the pathogenesis and therapy of itch.
Biochim. Biophys. Acta 1772: 1004-1021 (2007).
*
-
Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses.
J. Biol. Chem. 282: 31882-31890 (2007).
*
-
Biscetti F, Straface G, Pitocco D, Zaccardi F, Ghirlanda G, Flex A. Peroxisome proliferator-activated receptors and angiogenesis.
Nutr. Metab. Cardiovasc. Dis. 19: 751-759 (2009).
-
Bises G, Bajna E, Manhardt T, Gerdenitsch W, Kallay E, Cross HS. Gender-specific modulation of markers for premalignancy by nutritional soy and calcium in the mouse colon.
J. Nutr. 137: 211S-215S (2007).
*
-
Bisgaard HC, Holmskov U, Santoni-Rugiu E, Nagy P, Nielsen O, Ott P, Hage E, Dalhoff K, Rasmussen LJ, Tygstrup N. Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1.
Am. J. Pathol. 161: 1187-1198 (2002).
*
-
Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas.
Gastroenterology 130: 137-149 (2006).
*
-
Bishnupuri KS, Luo Q, Sainathan SK, Kikuchi K, Sureban SM, Sabarinathan M, Gross JH, Aden K, May R, Houchen CW, Anant S, Dieckgraefe BK. Reg IV regulates normal intestinal and colorectal cancer cell susceptibility to radiation-induced apoptosis.
Gastroenterology 138: 616-626.e2 (2010).
*
-
Bishop-Bailey D, Bystrom J. Emerging roles of peroxisome proliferator-activated receptor-beta/delta in inflammation.
Pharmacol. Ther. 124: 141-150 (2009).
*
-
Bisping G, Lugering N, Lutke-Brintrup S, Pauels HG, Schurmann G, Domschke W, Kucharzik T. Patients with inflammatory bowel disease (IBD) reveal increased induction capacity of intracellular interferon-gamma (IFN-gamma) in peripheral CD8+ lymphocytes co-cultured with intestinal epithelial cells.
Clin. Exp. Immunol. 123: 15-22 (2001).
*
-
Bissig KD, Le TT, Woods NB, Verma IM. Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model.
Proc. Natl. Acad. Sci. U.S.A. 104: 20507-20511 (2007).
*
-
Bissonnette M, Khare S, von Lintig FC, Wali RK, Nguyen L, Zhang Y, Hart J, Skarosi S, Varki N, Boss GR, Brasitus TA. Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1.
Cancer Res. 60: 4602-4609 (2000).
*
-
Bissonnette RP, Brunner T, Lazarchik SB, Yoo NJ, Boehm MF, Green DR, Heyman RA. 9-cis Retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of Fas ligand and requires retinoic acid receptor and retinoid X receptor activation.
Mol. Cell. Biol. 15: 5576-5585 (1995).
*
-
Bister V, Makitalo L, Jeskanen L, Saarialho-Kere U. Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum.
J. Cutan. Pathol. 34: 889-898 (2007).
*
-
Biswas PS, Pedicord V, Ploss A, Menet E, Leiner I, Pamer EG. Pathogen-specific CD8 T cell responses are directly inhibited by IL-10.
J. Immunol. 179: 4520-4528 (2007).
*
-
Bittencourt PL, Palacios SA, Cancado EL, Porta G, Carrilho FJ, Laudanna AA, Kalil J, Goldberg AC. Cytotoxic T lymphocyte antigen-4 gene polymorphisms do not confer susceptibility to autoimmune hepatitis types 1 and 2 in Brazil.
Am. J. Gastroenterol. 98: 1616-1620 (2003).
*
-
Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, Bottinger EP. A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA.
Genes Dev. 14: 187-197 (2000).
*
-
Bjerkeli V, Halvorsen B, Damas JK, Nordoy I, Yndestad A, Aukrust P, Froland SS. Expression of matrix metalloproteinases in patients with Wegener's granulomatosis.
Ann. Rheum. Dis. 63: 1659-1663 (2004).
*
-
Bjerrum JT, Hansen M, Olsen J, Nielsen OH. Genome-wide gene expression analysis of mucosal colonic biopsies and isolated colonocytes suggests a continuous inflammatory state in the lamina propria of patients with quiescent ulcerative colitis.
Inflamm. Bowel Dis. Oct 15 [Epub ahead of print] (2009).
*
-
Bjorkholm B, Bok CM, Lundin A, Rafter J, Hibberd ML, Pettersson S. Intestinal microbiota regulate xenobiotic metabolism in the liver.
PLoS One 4: e6958 (2009).
*
-
Bjornsson E, Chapman RW. Sclerosing cholangitis.
Curr. Opin. Gastroenterol. 19: 270-275 (2003).
-
Bjorses P, Halonen M, Palvimo JJ, Kolmer M, Aaltonen J, Ellonen P, Perheentupa J, Ulmanen I, Peltonen L. Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein.
Am. J. Hum. Genet. 66: 378-392 (2000).
*
-
Bjorses P, Pelto-Huikko M, Kaukonen J, Aaltonen J, Peltonen L, Ulmanen I. Localization of the APECED protein in distinct nuclear structures.
Hum. Mol. Genet. 8: 259-266 (1999).
*
-
Blaas L, Kornfeld JW, Schramek D, Musteanu M, Zollner G, Gumhold J, van Zijl F, Schneller D, Esterbauer H, Egger G, Mair M, Kenner L, Mikulits W, Eferl R, Moriggl R, Penninger J, Trauner M, Casanova E. Disruption of the growth hormone-signal transducer and activator of transcription 5-insulinlike growth factor 1 axis severely aggravates liver fibrosis in a mouse model of cholestasis.
Hepatology Nov 30 [Epub ahead of print] (2009).
-
Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism.
J. Hepatol. 40: 942-951 (2004).
*
-
Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia.
Glia 57: 1072-1081 (2009).
*
-
Black JA, Newcombe J, Trapp BD, Waxman SG. Sodium channel expression within chronic multiple sclerosis plaques.
J. Neuropathol. Exp. Neurol. 66: 828-837 (2007).
-
Blackledge NP, Carter EJ, Evans JR, Lawson V, Rowntree RK, Harris A. CTCF mediates insulator function at the CFTR locus.
Biochem. J. 408: 267-275 (2007).
*
-
Blackledge NP, Ott CJ, Gillen AE, Harris A. An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells.
Nucleic Acids Res. 37: 1086-1094 (2009).
*
-
Blackwell JM. Structure and function of the natural-resistance-associated macrophage protein (Nramp1), a candidate protein for infectious and autoimmune disease susceptibility.
Mol. Med. Today 2: 205-211 (1996).
-
Blackwell JM, Searle S. Genetic regulation of macrophage activation: understanding the function of Nramp1 (=Ity/Lsh/Bcg).
Immunol. Lett. 65: 73-80 (1999).
-
Blackwell K, Zhang L, Thomas GS, Sun S, Nakano H, Habelhah H. TRAF2 phosphorylation modulates TNFalpha-induced gene expression and cell resistance to apoptosis.
Mol. Cell. Biol. 29: 303-314 (2009).
*
-
Blair SA, Kane SV, Clayburgh DR, Turner JR. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease.
Lab. Invest. 86: 191-201 (2006).
*
-
Blais M, Seidman EG, Asselin C. Dual effect of butyrate on IL-1beta-mediated intestinal epithelial cell inflammatory response.
DNA Cell Biol. 26: 133-147 (2007).
-
Blanchard C, Durual S, Estienne M, Emami S, Vasseur S, Cuber JC. Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6.
Int. J. Biochem. Cell. Biol. 37: 2559-2573 (2005).
*
-
Blanchard C, Mingler MK, Vicario M, Abonia JP, Wu YY, Lu TX, Collins MH, Putnam PE, Wells SI, Rothenberg ME. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids.
J. Allergy Clin. Immunol. 120: 1292-1300 (2007).
*
-
Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis.
J. Clin. Invest. 116: 536-547 (2006).
*
-
Blanchard RK, Cousins RJ. Regulation of intestinal gene expression by dietary zinc: induction of uroguanylin mRNA by zinc deficiency.
J. Nutr. 130: 1393S-1398S (2000).
*
-
Blanchard TG, Drakes ML, Czinn SJ. Helicobacter infection: pathogenesis.
Curr. Opin. Gastroenterol. 20: 10-15 (2004).
-
Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF. Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus.
Arthritis Rheum. 52: 201-211 (2005).
*
-
Blank C, Gajewski TF, Mackensen A. Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy.
Cancer Immunol. Immunother. 54: 307-314 (2005).
*
-
Blank M, Shoenfeld Y. The story of the 16/6 idiotype and systemic lupus erythematosus.
Isr. Med. Assoc. J. 10: 37-39 (2008).
*
-
Blank M, Shoenfeld Y, Perl A. Cross-talk of the environment with the host genome and the immune system through endogenous retroviruses in systemic lupus erythematosus.
Lupus 18: 1136-1143 (2009).
-
Blank MC, Stefanescu RN, Masuda E, Marti F, King PD, Redecha PB, Wurzburger RJ, Peterson MG, Tanaka S, Pricop L. Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus.
Hum. Genet. 117: 220-227 (2005).
*
-
Blankenhorn EP, Cort L, Greiner DL, Guberski DL, Mordes JP. Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex.
Diabetes 58: 2930-2938 (2009).
-
Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection.
Diabetes 54: 1233-1237 (2005).
*
-
Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C. Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes.
J. Biol. Chem. 277: 37254-37259 (2002).
*
-
Blaschke F, Takata Y, Caglayan E, Collins A, Tontonoz P, Hsueh WA, Tangirala RK. A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor.
Circ. Res. 99: e88-e99 (2006).
*
-
Blaschke S, Brandt P, Wessels JT, Muller GA. Expression and function of the C-class chemokine lymphotactin (XCL1) in Wegener's granulomatosis.
J. Rheumatol. 36: 2491-2500 (2009).
-
Blechacz B, Splinter PL, Greiner S, Myers R, Peng KW, Federspiel MJ, Russell SJ, LaRusso NF. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma.
Hepatology 44: 1465-1477 (2006).
*
-
Blechschmidt K, Schweiger M, Wertz K, Poulson R, Christensen HM, Rosenthal A, Lehrach H, Yaspo ML. The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.
Genome Res. 9: 158-166 (1999).
*
-
Bleiber G, May M, Suarez C, Martinez R, Marzolini C, Egger M, Telenti A; Swiss HIV Cohort Study. MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment.
J. Infect. Dis. 189: 583-586 (2004).
*
-
Bleich A, Buchler G, Beckwith J, Petell LM, Affourtit JP, King BL, Shaffer DJ, Roopenian DC, Hedrich HJ, Sundberg JP, Leiter EH. Cdcs1 a major colitis susceptibility locus in mice; subcongenic analysis reveals genetic complexity.
Inflamm. Bowel Dis. Oct 23 [Epub ahead of print] (2009).
-
Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice.
J. Clin. Invest. 103: 1431-1436 (1999).
*
-
Bleiziffer O, Horch RE, Hammon M, Arkudas A, Naschberger E, Rath S, Pryymachuk G, Beier JP, Hatzopoulos AK, Sturzl M, Kneser U. T17b murine embryonal endothelial progenitor cells can be induced towards both proliferation and differentiation in a fibrin matrix.
J. Cell. Mol. Med. 13: 926-935 (2009).
*
-
Blenman KR, Duan B, Xu Z, Wan S, Atkinson MA, Flotte TR, Croker BP, Morel L. IL-10 regulation of lupus in the NZM2410 murine model.
Lab. Invest. 86: 1136-1148 (2006).
*
-
Bloch DB, de la Monte SM, Guigaouri P, Filippov A, Bloch KD. Identification and characterization of a leukocyte-specific component of the nuclear body.
J. Biol. Chem. 271: 29198-29204 (1996).
*
-
Bloemen V, de Vries TJ, Schoenmaker T, Everts V. Intercellular adhesion molecule-1 clusters during osteoclastogenesis.
Biochem. Biophys. Res. Commun. 385: 640-645 (2009).
*
-
Bloemen V, Schoenmaker T, de Vries TJ, Everts V. Direct cell-cell contact between periodontal ligament fibroblasts and osteoclast precursors synergistically increases the expression of genes related to osteoclastogenesis.
J. Cell. Physiol. 222: 565-573 (2009).
-
Blokzijl H, Vander Borght S, Bok LI, Libbrecht L, Geuken M, van den Heuvel FA, Dijkstra G, Roskams TA, Moshage H, Jansen PL, Faber KN. Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.
Inflamm. Bowel Dis. 13: 710-720 (2007).
*
-
Bloomer J, Wang Y, Singhal A, Risheg H. Molecular studies of liver disease in erythropoietic protoporphyria.
J. Clin. Gastroenterol. 39: S167-S175 (2005).
-
Bloquel C, Bessis N, Boissier MC, Scherman D, Bigey P. Gene therapy of collagen-induced arthritis by electrotransfer of human tumor necrosis factor-alpha soluble receptor I variants.
Hum. Gene Ther. 15: 189-201 (2004).
*
-
Bluestone JA. A balanced attack.
The Scientist May, 2007 (http://www.the-scientist.com/2007/05/01/s32/1/ ) (2007).
-
Blum A, Setiawan T, Hang L, Stoyanoff K, Weinstock JV. Interleukin-12 (IL-12) and IL23 induction of substance P synthesis in murine T cells and macrophages is subject to IL10 and TGFbeta regulation.
Infect. Immun. 76: 3651-3656 (2008).
*
-
Blum HE. Treatment of hepatocellular carcinoma.
Best Pract. Res. Clin. Gastroenterol. 19: 129-145 (2005).
-
Blum HE. Hepatocellular carcinoma: therapy and prevention.
World J. Gastroenterol. 11: 7391-7400 (2005).
*
-
Blum HE. Gene therapy for liver diseases: experimental strategies.
Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 44-45 (2006). *
-
Blum R, Gupta R, Burger PE, Ontiveros CS, Salm SN, Xiong X, Kamb A, Wesche H, Marshall L, Cutler G, Wang X, Zavadil J, Moscatelli D, Wilson EL. Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer.
PLoS ONE 4: e5722 (2009).
*
-
Blumberg B, Mangelsdorf DJ, Dyck JA, Bittner DA, Evans RM, De Robertis EM. Multiple retinoid-responsive receptors in a single cell: families of retinoid "X" receptors and retinoic acid receptors in the Xenopus egg.
Proc. Natl. Acad. Sci. U.S.A. 89: 2321-2325 (1992).
*
-
Blumberg B, Sabbagh W Jr, Juguilon H, Bolado J Jr, van Meter CM, Ong ES, Evans RM. SXR, a novel steroid and xenobiotic-sensing nuclear receptor.
Genes Dev. 12: 3195-3205 (1998).
*
-
Blumberg JM, Tzameli I, Astapova I, Lam FS, Flier JS, Hollenberg AN. Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells.
J. Biol. Chem. 281: 11205-11213 (2006).
*
-
Blumerman SL, Herzig CT, Wang F, Coussens PM, Baldwin CL. Comparison of gene expression by co-cultured WC1(+) gammadelta and CD4(+) alphabeta T cells exhibiting a recall response to bacterial antigen.
Mol. Immunol. 44: 2033-2045 (2007).
*
-
Bluthner M, Schafer C, Schneider C, Bautz FA. Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology.
Autoimmunity 29: 33-42 (1999).
-
Blyth K, Vaillant F, Hanlon L, Mackay N, Bell M, Jenkins A, Neil JC, Cameron ER. Runx2 and MYC collaborate in lymphoma development by suppressing apoptotic and growth arrest pathways in vivo.
Cancer Res. 66: 2195-2201 (2006).
*
-
Bo X, Broome U, Remberger M, Sumitran-Holgersson S. Tumour necrosis factor alpha impairs function of liver derived T lymphocytes and natural killer cells in patients with primary sclerosing cholangitis.
Gut 49: 131-141 (2001).
*
-
Boadu E, Choi HY, Lee DW, Waddington EI, Chan T, Asztalos B, Vance JE, Chan A, Castro G, Francis GA. Correction of apolipoprotein A-I-mediated lipid efflux and HDL particle formation in human Niemann-Pick type C disease fibroblasts.
J. Biol. Chem. 281: 37081-37090 (2006).
*
-
Bobacz K, Sunk IG, Hofstaetter JG, Amoyo L, Toma CD, Akira S, Weichhart T, Saemann M, Smolen JS. Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of Toll-like receptor 4 and antagonized by bone morphogenetic protein 7.
Arthritis Rheum. 56: 1880-1893 (2007).
*
-
Boberg J, Metzdorff S, Wortziger R, Axelstad M, Brokken L, Vinggaard AM, Dalgaard M, Nellemann C. Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats.
Toxicology 250: 75-81 (2008).
*
-
Boberg KM, Lundin KE, Schrumpf E. Etiology and pathogenesis in primary sclerosing cholangitis.
Scand. J. Gastroenterol. Suppl. 204: 47-58 (1994).
-
Boberg KM, Schrumpf E. Diagnosis and treatment of cholangiocarcinoma.
Curr. Gastroenterol. Rep. 6: 52-59 (2004).
-
Bocca C, Bozzo F, Francica S, Colombatto S, Miglietta A. Involvement of PPARgamma and E-cadherin/beta-catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells.
Int. J. Cancer 121: 248-256 (2007).
*
-
Bocca C, Bozzo F, Martinasso G, Canuto RA, Miglietta A. Involvement of PPARalpha in the growth inhibitory effect of arachidonic acid on breast cancer cells.
Br. J. Nutr. 100: 739-750 (2008).
*
-
Bocher V, Pineda-Torra I, Fruchart JC, Staels B. PPARs: transcription factors controlling lipid and lipoprotein metabolism.
Ann. N. Y. Acad. Sci. 967: 7-18 (2002).
*
-
Bochkis IM, Rubins NE, White P, Furth EE, Friedman JR, Kaestner KH. Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress.
Nat. Med. 14: 828-836 (2008).
*
-
Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state.
Physiol. Genomics 38: 186-195 (2009).
*
-
Bock C, Lengauer T. Computational epigenetics.
Bioinformatics 24: 1-10 (2008).
*
-
Bock HH, Lammert F. Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense.
Hepatology 35: 232-234 (2002).
*
-
Bock KW, Kohle C. UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects.
Methods Enzymol. 400: 57-75 (2005).
-
Bockelmann R, Horn T, Gollnick H, Bonnekoh B. Interferon-gamma-dependent in vitro model for the putative keratin 17 autoimmune loop in psoriasis: exploration of pharmaco- and gene-therapeutic effects.
Skin Pharmacol. Physiol. 18: 42-54 (2005).
-
Bodaghi B, Rao N. Relevance of animal models to human uveitis.
Ophthalmic Res. 40: 200-202 (2008).
-
Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, Sweet MJ, Dalpke AH. Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment.
Immunology 122: 596-606 (2007).
*
-
Boden G, Zhang M. Recent findings concerning thiazolidinediones in the treatment of diabetes.
Expert Opin. Investig. Drugs 15: 243-250 (2006).
-
Bodger K, Halfvarson J, Dodson A, Campbell F, Wilson S, Lee R, Lindberg E, Jarnerot G, Tysk C, Rhodes J. Altered colonic glycoprotein expression in unaffected monozygotic twins of inflammatory bowel disease patients.
Gut 55: 973-977 (2006).
*
-
Bodin K. Role of CYP3A4 as a cholesterol and bile acid metabolizing enzyme.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 25. June 18-19 (2004). *
-
Boettler T, Panther E, Bengsch B, Nazarova N, Spangenberg HC, Blum HE, Thimme R. Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection.
J. Virol. 80: 3532-3540 (2006).
*
-
Bogazzi F, Bartalena L, Brogioni S, Burelli A, Grasso L, Dell'Unto E, Manetti L, Martino E. L-Thyroxine directly affects expression of thyroid hormone-sensitive genes: regulatory effect of RXRbeta.
Mol. Cell. Endocrinol. 134: 23-31 (1997).
-
Bogert PT, LaRusso NF. Cholangiocyte biology.
Curr. Opin. Gastroenterol. 23: 299-305 (2007).
-
Bogoch Y, Linial M. Coordinated expression of cytoskeleton regulating genes in the accelerated neurite outgrowth of P19 embryonic carcinoma cells.
Exp. Cell Res. 314: 677-690 (2008).
*
-
Bogoevska V, Horst A, Klampe B, Lucka L, Wagener C, Nollau P. CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via LewisX residues.
Glycobiology 16: 197-209 (2006).
*
-
Bogunia-Kubik K, Jaskula E, Lange A. The presence of functional CCR5 and EBV reactivation after allogeneic haematopoietic stem cell transplantation.
Bone Marrow Transplant. 40: 145-150 (2007).
-
Bogunovic M, Dave SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, Mayer LF, Plevy SE. Enteroendocrine cells express functional Toll-like receptors.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1770-G1783 (2007).
*
-
Bohan A, Boyer JL. Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions.
Semin. Liver Dis. 22: 123-136 (2002).
-
Bohgaki T, Amasaki Y, Nishimura N, Bohgaki M, Yamashita Y, Nishio M, Sawada KI, Jodo S, Atsumi T, Koike T. Up regulated expression of tumour necrosis factor alpha converting enzyme in peripheral monocytes of patients with early systemic sclerosis.
Ann. Rheum. Dis. 64: 1165-1173 (2005).
*
-
Bohlken A, Cheung BB, Bell JL, Koach J, Smith S, Sekyere E, Thomas W, Norris M, Haber M, Lovejoy DB, Richardson DR, Marshall GM. ATP7A is a novel target of retinoic acid receptor beta2 in neuroblastoma cells.
Br. J. Cancer 100: 96-105 (2009).
*
-
Bohm C, Hayer S, Kilian A, Zaiss MM, Finger S, Hess A, Engelke K, Kollias G, Kronke G, Zwerina J, Schett G, David JP. The alpha-isoform of p38 MAPK specifically regulates arthritic bone loss.
J. Immunol. 183: 5938-5947 (2009).
-
Bohn E, Bechtold O, Zahir N, Frick JS, Reimann J, Jilge B, Autenrieth IB. Host gene expression in the colon of gnotobiotic interleukin-2-deficient mice colonized with commensal colitogenic or noncolitogenic bacterial strains: common patterns and bacteria strain specific signatures.
Inflamm. Bowel Dis. 12: 853-862 (2006).
*
-
Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schaffer AA, Rathinam C, Taub N, Teis D, Zeidler C, Dewey RA, Geffers R, Buer J, Huber LA, Welte K, Grimbacher B, Klein C. A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14.
Nat. Med. 13: 38-45 (2007).
*
-
Bohren KM, Nadkarni V, Song JH, Gabbay KH, Owerbach D. A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus.
J. Biol. Chem. 279: 27233-27238 (2004).
*
-
Bois-Joyeux B, Chauvet C, Nacer-Cherif H, Bergeret W, Mazure N, Giguere V, Laudet V, Danan JL. Modulation of the far-upstream enhancer of the rat alpha-fetoprotein gene by members of the ROR alpha, Rev-erb alpha, and Rev-erb beta groups of monomeric orphan nuclear receptors.
DNA Cell Biol. 19: 589-599 (2000).
-
Boitier E, Gautier JC, Roberts R. Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease.
Comp. Hepatol. 2: 3 (2003).
*
-
Boj SF, Servitja JM, Martin D, Rios M, Talianidis I, Guigo R, Ferrer J. Functional targets of the monogenic diabetes transcription factors HNF-1alpha and HNF-4alpha are highly conserved between mice and humans.
Diabetes 58: 1245-1253 (2009).
-
Bolland D, Corcoran A. Somatic hypermutation is a matter of choice.
Nat. Immunol. 8: 677-679 (2007).
*
-
Bolotin E, Liao H, Ta TC, Yang C, Hwang-Verslues W, Evans JR, Jiang T, Sladek FM. Integrated approach for the identification of human hepatocyte nuclear factor 4alpha target genes using protein binding microarrays.
Hepatology 51: 642-653 (2010).
*
-
Bolstad AI, Jonsson R. Gene therapeutics in Sjogren's syndrome.
Expert Opin. Biol. Ther. 5: 763-772 (2005).
-
Bolt HM. Rifampicin, a keystone inducer of drug metabolism: from Herbert Remmer's pioneering ideas to modern concepts.
Drug Metab. Rev. 36: 497-509 (2004).
-
Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C. Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous simian immunodeficiency virus-specific CD8+ T cell clones during acute and chronic infection of Rhesus macaques.
J. Immunol. 184: 303-314 (2010).
-
Bombail V, Taylor K, Gibson GG, Plant N. Role of Sp1, C/EBPalpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene.
Drug Metab. Dispos. 32: 525-535 (2004).
*
-
Bommareddy A, Arasada BL, Mathees DP, Dwivedi C. Chemopreventive effects of dietary flaxseed on colon tumor development.
Nutr. Cancer 54: 216-222 (2006).
*
-
Bommareddy A, Zhang X, Schrader D, Kaushik RS, Zeman D, Matthees DP, Dwivedi C. Effects of dietary flaxseed on intestinal tumorigenesis in apc(min) mouse.
Nutr. Cancer 61: 276-283 (2009).
-
Bommireddy R, Doetschman T. TGFbeta1 and T(reg) cells: alliance for tolerance.
Trends Mol. Med. 13: 492-501 (2007).
*
-
Bommireddy R, Pathak LJ, Martin J, Ormsby I, Engle SJ, Boivin GP, Babcock GF, Eriksson AU, Singh RR, Doetschman T. Self-antigen recognition by TGFbeta1-deficient T cells causes their activation and systemic inflammation.
Lab. Invest. 86: 1008-1019 (2006).
*
-
Boncoeur E, Criq VS, Bonvin E, Roque T, Henrion-Caude A, Gruenert DC, Clement A, Jacquot J, Tabary O. Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: potential mechanism for excessive IL-8 expression.
Int. J. Biochem. Cell Biol. 40: 432-446 (2008).
*
-
Bondeva T, Roger T, Wolf G. Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites.
Am. J. Nephrol. 27: 308-314 (2007).
-
Bonelli M, Savitskaya A, Steiner CW, Rath E, Smolen JS, Scheinecker C. Phenotypic and functional analysis of CD4+CD25-Foxp3+ T cells in patients with systemic lupus erythematosus.
J. Immunol. 182: 1689-1695 (2009).
-
Bonelli M, Savitskaya A, von Dalwigk K, Steiner CW, Aletaha D, Smolen JS, Scheinecker C. Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE).
Int. Immunol. 20: 861-868 (2008).
-
Bonelli M, von Dalwigk K, Savitskaya A, Smolen JS, Scheinecker C. Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus: a comparative phenotypic analysis.
Ann. Rheum. Dis. 67: 664-671 (2008).
-
Bonet ML, Ribot J, Felipe F, Palou A. Vitamin A and the regulation of fat reserves.
Cell. Mol. Life Sci. 60: 1311-1321 (2003).
-
Bonewald LF. Osteocytes: a proposed multifunctional bone cell.
J. Musculoskelet. Neuronal Interact. 2: 239-241 (2002).
-
Bonfield TL, Barna BP, John N, Malur A, Culver DA, Kavuru MS, Thomassen MJ. Suppression of activin A in autoimmune lung disease associated with anti-GM-CSF.
J. Autoimmun. 26: 37-41 (2006).
-
Bonfield TL, Swaisgood CM, Barna BP, Farver CF, Kavuru MS, Thomassen MJ. Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor.
J. Leukoc. Biol. 79: 133-139 (2006).
*
-
Bonfield TL, Thomassen MJ, Farver CF, Abraham S, Koloze MT, Zhang X, Mosser DM, Culver DA. Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor.
J. Immunol. 181: 235-242 (2008).
*
-
Bonhomme-Faivre L, Devocelle A, Saliba F, Chatled S, Maccario J, Farinotti R, Picard V. MDR-1 C3435T polymorphism influences cyclosporine A dose requirement in liver-transplant recipients.
Transplantation 78: 21-25 (2004).
-
Bonif M, Meuwis MA, Close P, Benoit V, Heyninck K, Chapelle JP, Bours V, Merville MP, Piette J, Beyaert R, Chariot A. TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation.
Biochem. J. 394: 593-603 (2006).
*
-
Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes.
J. Immunol. 174: 3695-3702 (2005).
*
-
Boniface K, Blom B, Liu YJ, de Waal Malefyt R. From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited.
Immunol. Rev. 226: 132-146 (2008).
*
-
Boniface K, Diveu C, Morel F, Pedretti N, Froger J, Ravon E, Garcia M, Venereau E, Preisser L, Guignouard E, Guillet G, Dagregorio G, Pene J, Moles JP, Yssel H, Chevalier S, Bernard FX, Gascan H, Lecron JC. Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation.
J. Immunol. 178: 4615-4622 (2007).
*
-
Boniface K, Lecron JC, Bernard FX, Dagregorio G, Guillet G, Nau F, Morel F. Keratinocytes as targets for interleukin-10-related cytokines: a putative role in the pathogenesis of psoriasis.
Eur. Cytokine Netw. 16: 309-319 (2005).
-
Bonin S, Pascolo L, Croce LS, Stanta G, Tiribelli C. Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases.
Mol. Med. 8: 318-325 (2002).
*
-
Boniotto M, Radillo O, Braida L, Pirulli D, Citta A, Not T, Amoroso A, Crovella S. Detection of MBL-2 gene expression in intestinal biopsies of celiac patients by in situ reverse transcription polymerase chain reaction.
Eur. J. Histochem. 47: 177-180 (2003).
-
Bonnefont-Rebeix C, Marchal T, Bernaud J, Pin JJ, Leroux C, Lebecque S, Chabanne L, Rigal D. Toll-like receptor 3 (TLR3): a new marker of canine monocytes-derived dendritic cells (cMo-DC).
Vet. Immunol. Immunopathol. 118: 134-139 (2007).
*
-
Bonnekoh B, Pommer AJ, Bockelmann R, Hofmeister H, Philipsen L, Gollnick H. Topo-proteomic in situ analysis of psoriatic plaque under efalizumab treatment.
Skin Pharmacol. Physiol. 20: 237-252 (2007).
-
Bonnet E, Touyarot K, Alfos S, Pallet V, Higueret P, Abrous DN. Retinoic acid restores adult hippocampal neurogenesis and reverses spatial memory deficit in vitamin A deprived rats.
PLoS ONE 3: e3487 (2008).
*
-
Bonzheim I, Geissinger E, Chuang WY, Roth S, Strobel P, Marx A, Reimer P, Wilhelm M, Puppe B, Rosenwald A, Muller-Hermelink HK, Rudiger T. Analysis of single nucleotide polymorphisms in the FAS and CTLA-4 genes of peripheral T-cell lymphomas.
J. Hematop. 1: 11-21 (2008).
*
-
Boodhoo A, Wong AM, Williamson D, Voon D, Lee S, Allcock RJ, Price P. A promoter polymorphism in the central MHC gene, IKBL, influences the binding of transcription factors USF1 and E47 on disease-associated haplotypes.
Gene Expr. 12: 1-11 (2004).
-
Booij-Vrieling HE, Ferbus D, Tryfonidou MA, Riemers FM, Penning LC, Berdal A, Everts V, Hazewinkel HA. Increased vitamin D-driven signalling and expression of the vitamin D receptor, MSX2, and RANKL in tooth resorption in cats.
Eur. J. Oral Sci. 118: 39-46 (2010).
-
Bookout AL, Mangelsdorf DJ. Quantitative real-time PCR protocol for analysis of nuclear receptor signaling pathways.
Nucl. Recept. Signal. 1: e012 (2003).
*
-
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, Hurley P, Chien M, Chai S, Hitotsumatsu O, McNally E, Pickart C, Ma A. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses.
Nat. Immunol. 5: 1052-1060 (2004).
*
-
Boonsaen T, Rojvirat P, Surinya KH, Wallace JC, Jitrapakdee S. Transcriptional regulation of the distal promoter of the rat pyruvate carboxylase gene by hepatocyte nuclear factor 3beta/Foxa2 and upstream stimulatory factors in insulinoma cells.
Biochem. J. 405: 359-367 (2007).
*
-
Booth DR, Arthur AT, Teutsch SM, Bye C, Rubio J, Armati PJ, Pollard JD, Heard RN, Stewart GJ; The Southern MS Genetics Consortium. Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis.
J. Mol. Med. 83: 822-830 (2005).
*
-
Booth G, Newham P, Barlow R, Raines S, Zheng B, Han S. Gene expression profiles at different stages of collagen-induced arthritis.
Autoimmunity 41: 512-521 (2008).
-
Boothby M. The calculus of integrating differentiation: timing control of T-bet.
Immunity 30: 666-668 (2009).
*
-
Booty MG, Chae JJ, Masters SL, Remmers EF, Barham B, Le JM, Barron KS, Holland SM, Kastner DL, Aksentijevich I. Familial Mediterranean fever with a single MEFV mutation: where is the second hit?
Arthritis Rheum. 60: 1851-1861 (2009).
-
Boquoi A, Jover R, Chen T, Pennings M, Enders G. Transgenic expression of VEGF in intestinal epithelium drives mesenchymal cell interactions and epithelial neoplasia.
Gastroenterology 136: 596-606.e4 (2009).
*
-
Boraska V, Torlak V, Skrabic V, Kacic Z, Jaksic J, Stipancic G, Spehar A, Markotic A, Zemunik T. Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population.
Clin. Biochem. 42: 819-822 (2009).
*
-
Borchers AT, Naguwa SM, Shoenfeld Y, Gershwin ME. The geoepidemiology of systemic lupus erythematosus.
Autoimmun. Rev. Dec 23 [Epub ahead of print] (2009).
-
Borchers MT, Wesselkamper SC, Curull V, Ramirez-Sarmiento A, Sanchez-Font A, Garcia-Aymerich J, Coronell C, Lloreta J, Agusti AG, Gea J, Howington JA, Reed MF, Starnes SL, Harris NL, Vitucci M, Eppert BL, Motz GT, Fogel K, McGraw DW, Tichelaar JW, et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.
J. Clin. Invest. 119: 636-649 (2009).
*
-
Bordoni A, Di Nunzio M, Danesi F, Biagi PL. Polyunsaturated fatty acids: from diet to binding to PPARs and other nuclear receptors.
Genes Nutr. 1: 95-106 (2006).
*
-
Bordoni V, Alonzi T, Zanetta L, Khouri D, Conti A, Corazzari M, Bertolini F, Antoniotti P, Pisani G, Tognoli F, Dejana E, Tripodi M. Hepatocyte-conditioned medium sustains endothelial differentiation of human hematopoietic-endothelial progenitors.
Hepatology 45: 1218-1228 (2007).
*
-
Borel V, Marceau G, Gallot D, Blanchon L, Sapin V. Retinoids regulate human amniotic tissue-type plasminogen activator gene by a two-step mechanism.
J. Cell. Mol. Med. Jun 16 [Epub ahead of print] (2009).
*
-
Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily.
Biochem. Biophys. Res. Commun. 357: 977-983 (2007).
*
-
Borge BA, Kalland KH, Olsen S, Bletsa A, Berggreen E, Wiig H. Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia.
Am. J. Physiol. Heart Circ. Physiol. 296: H735-H744 (2009).
*
-
Borghaei RC, Gorski G, Javadi M, Chambers M. NF-kappaB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter.
Biochem. Biophys. Res. Commun. 382: 269-273 (2009).
*
-
Borghi A, Fogli E, Stignani M, Melchiorri L, Altieri E, Baricordi O, Rizzo R, Virgili A. Soluble human leukocyte antigen-G and interleukin-10 levels in plasma of psoriatic patients: preliminary study on a possible correlation between generalized immune status, treatments and disease.
Arch. Dermatol. Res. 300: 551-559 (2008).
*
-
Borgmann S, Haubitz M. Genetic impact of pathogenesis and prognosis of ANCA-associated vasculitides.
Clin. Exp. Rheumatol. 22 (6 Suppl. 36): S79-S86 (2004).
-
Borgogni E, Sarchielli E, Sottili M, Santarlasci V, Cosmi L, Gelmini S, Lombardi A, Cantini G, Perigli G, Luconi M, Vannelli GB, Annunziato F, Adorini L, Serio M, Crescioli C. Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells.
Endocrinology 149: 3626-3634 (2008).
*
-
Borlak J, Niehof M. HNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus.
PLoS One 4: e4662 (2009).
*
-
Borland MG, Foreman JE, Girroir EE, Zolfaghari R, Sharma AK, Amin SM, Gonzalez FJ, Ross AC, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell proliferation in human HaCaT keratinocytes.
Mol. Pharmacol. 74: 1429-1442 (2008).
*
-
Borm ME, He J, Kelsall B, Pena AS, Strober W, Bouma G. A major quantitative trait locus on mouse chromosome 3 is involved in disease susceptibility in different colitis models.
Gastroenterology 128: 74-85 (2005).
*
-
Borregaard N, Sorensen OE, Theilgaard-Monch K. Neutrophil granules: a library of innate immunity proteins.
Trends Immunol. 28: 340-345 (2007).
*
-
Borrego F, Kabat J, Kim DK, Lieto L, Maasho K, Pena J, Solana R, Coligan JE. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells.
Mol. Immunol. 38: 637-660 (2002).
*
-
Borruel N, Carol M, Casellas F, Antolín M, de Lara F, Espín E, Naval J, Guarner F, Malagelada JR. Increased mucosal tumour necrosis factor alpha production in Crohn's disease can be downregulated ex vivo by probiotic bacteria.
Gut 51: 659-664 (2002).
*
-
Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins.
J. Natl. Cancer Inst. 92: 1295-1302 (2000).
*
-
Borthakur A, Bhattacharyya S, Alrefai WA, Tobacman JK, Ramaswamy K, Dudeja PK. Platelet-activating factor-induced NF-kappaB activation and IL-8 production in intestinal epithelial cells are Bcl10-dependent.
Inflamm. Bowel Dis. Aug 27 [Epub ahead of print] (2009).
-
Borthwick F, Taylor JM, Bartholomew C, Graham A. Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages.
FEBS Lett. 583: 1147-1153 (2009).
*
-
Borysiewicz E, Fil D, Konat GW. Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes.
J. Neurosci. Res. 87: 1565-1572 (2009).
-
Bos CL, Diks SH, Hardwick JC, Walburg KV, Peppelenbosch MP, Richel DJ. Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity.
Carcinogenesis 27: 2371-2382 (2006).
*
-
Bos CL, van Baarsen LG, Timmer TC, Overbeek MJ, Basoski NM, Rustenburg F, Baggen JM, Thiesen HJ, Dijkmans BA, van der Pouw Kraan TC, Voskuyl AE, Verweij CL. Molecular subtypes of systemic sclerosis in association with anti-centromere antibodies and digital ulcers.
Genes Immun. 10: 210-218 (2009).
-
Bosch TM, Deenen M, Pruntel R, Smits PH, Schellens JH, Beijnen JH, Meijerman I. Screening for polymorphisms in the PXR gene in a Dutch population.
Eur. J. Clin. Pharmacol. 62: 395-399 (2006).
*
-
Bosco MC, Delfino S, Ferlito F, Puppo M, Gregorio A, Gambini C, Gattorno M, Martini A, Varesio L. The hypoxic synovial environment regulates expression of vascular endothelial growth factor and osteopontin in juvenile idiopathic arthritis.
J. Rheumatol. 36: 1318-1329 (2009).
-
Bose JS, Gangan V, Jain SK, Manna SK. Novel caffeic acid ester derivative induces apoptosis by expressing Fasl and downregulating NF-kappaB: potentiation of cell death mediated by chemotherapeutic agents.
J. Cell. Physiol. 218: 653-662 (2008).
*
-
Bosello S, Pers JO, Rochas C, Devauchelle V, De Santis M, Daridon C, Saraux A, Ferraccioli GF, Youinou P. BAFF and rheumatic autoimmune disorders: implications for disease management and therapy.
Int. J. Immunopathol. Pharmacol. 20: 1-8 (2007).
-
Bosisio D, Vulcano M, Del Prete A, Sironi M, Salvi V, Salogni L, Riboldi E, Leoni F, Dinarello CA, Girolomoni G, Sozzani S. Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo.
J. Leukoc. Biol. 84: 1540-1548 (2008).
*
-
Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, Lindhout D, Tytgat GN, Jansen PL, Oude Elferink RP, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome.
N. Engl. J. Med. 333: 1171-1175 (1995).
*
-
Bossard C, Souaze F, Jarry A, Bezieau S, Mosnier JF, Forgez P, Laboisse CL. Over-expression of neurotensin high-affinity receptor 1 (NTS1) in relation with its ligand neurotensin (NT) and nuclear beta-catenin in inflammatory bowel disease-related oncogenesis.
Peptides 28: 2030-2035 (2007).
*
-
Bosse Y, Maghni K, Hudson TJ. 1alpha,25-Dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility and remodelling processes.
Physiol. Genomics 29: 161-168 (2007).
*
-
Bosse Y, Rola-Pleszczynski M. Controversy surrounding the increased expression of TGFbeta1 in asthma.
Respir. Res. 8: 66 (2007).
*
-
Bossowski A, Czarnocka B, Bardadin K, Stasiak-Barmuta A, Urban M, Dadan J, Ratomski K, Bossowska A. Identification of apoptotic proteins in thyroid gland from patients with Graves' disease and Hashimoto's thyroiditis.
Autoimmunity 41: 163-173 (2008).
-
Bossowski A, Czarnocka B, Stasiak-Barmuta A, Bardadin K, Urban M, Dadan J. Analysis of Fas, FasL and caspase-8 expression in thyroid gland in young patients with immune and non-immune thyroid diseases.
Endokrynol. Pol. 58: 303-313 (2007).
-
Bossu P, Ciaramella A, Moro ML, Bellincampi L, Bernardini S, Federici G, Trequattrini A, Macciardi F, Spoletini I, Di Iulio F, Caltagirone C, Spalletta G. Interleukin-18 gene polymorphisms predict risk and outcome of Alzheimer's disease.
J. Neurol. Neurosurg. Psychiatry 78: 807-811 (2007).
*
-
Bostjancic E, Glavac D. Importance of microRNAs in skin morphogenesis and diseases.
Acta Dermatovenerol. Alp. Panonica Adriat. 17: 95-102 (2008).
-
Bott C, Lembcke B, Stein J. Colorectal cancer and folate.
Z. Gastroenterol. 41: 263-270 (2003).
-
Bottcher I, Bellinghausen I, Konig B, Knop J, Saloga J. Different regulation of T helper 1- and T helper 2-promoting cytokine signalling factors in human dendritic cells after exposure to protein versus contact allergens.
Immunology 123: 139-144 (2008).
*
-
Bottcher S, Ritgen M, Bruggemann M, Raff T, Luschen S, Humpe A, Kneba M, Pott C. Flow cytometric assay for determination of FcgammaRIIIA-158 V/F polymorphism.
J. Immunol. Methods 306: 128-136 (2005).
*
-
Bottini N, Gloria-Bottini F, Lucarini N, Ronchetti PG, Fontana L. Inflammatory bowel disease: are there gender differences in the genetics of signal transduction? A preliminary study of cytosolic low molecular weight protein tyrosine phosphatase.
Dis. Markers 16: 163-166 (2000).
-
Bouali H, Nietert P, Nowling TM, Pandey J, Dooley MA, Cooper G, Harley J, Kamen DL, Oates J, Gilkeson G. Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus.
J. Rheumatol. 34: 2028-2034 (2007).
-
Bouazzaoui A, Spacenko E, Mueller G, Miklos S, Huber E, Holler E, Andreesen R, Hildebrandt GC. Chemokine and chemokine receptor expression analysis in target organs of acute graft-versus-host disease.
Genes Immun. 10: 687-701 (2009).
-
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M, Martin SJ. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways.
J. Biol. Chem. 276: 44069-44077 (2001).
*
-
Boudjelal M, Mason SJ, Katso RM, Fleming JM, Parham JH, Condreay JP, Merrihew RV, J Cairns W. The application of BacMam technology in nuclear receptor drug discovery.
Biotechnol. Annu. Rev. 11: 101-125 (2005).
-
Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K. PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB.
Proc. Natl. Acad. Sci. U.S.A. 106: 7397-7402 (2009).
*
-
Boughan PK, Argent RH, Body-Malapel M, Park JH, Ewings KE, Bowie AG, Ong SJ, Cook SJ, Sorensen OE, Manzo BA, Inohara N, Klein NJ, Nunez G, Atherton JC, Bajaj-Elliott M. Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection.
J. Biol. Chem. 281: 11637-11648 (2006).
*
-
Bouillon R, Verstuyf A, Mathieu C, Van Cromphaut S, Masuyama R, Dehaes P, Carmeliet G. Vitamin D resistance.
Best Pract. Res. Clin. Endocrinol. Metab. 20: 627-645 (2006).
-
Boulanger A, McLemore P, Copeland NG, Gilbert DJ, Jenkins NA, Yu SS, Gentleman S, Redmond TM. Identification of beta-carotene 15, 15'-monooxygenase as a peroxisome proliferator-activated receptor target gene.
FASEB J. 17: 1304-1306 (2003).
*
-
Boulanger DS, Oliveira R, Ayers L, Prior SH, James E, Williams AP, Elliott T. Absence of tapasin alters immunodominance against a lymphocytic choriomeningitis virus polytope.
J. Immunol. 184: 73-83 (2010).
-
Boulet LP. Influence of obesity on the prevalence and clinical features of asthma.
Clin. Invest. Med. 31: E386 (2008).
-
Boulet S, Kleyman M, Kim JY, Kamya P, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection.
AIDS 22: 1487-1491 (2008).
-
Boulet S, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals.
AIDS 22: 595-599 (2008).
-
Boulias K, Katrakili N, Bamberg K, Underhill P, Greenfield A, Talianidis I. Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.
EMBO J. 24: 2624-2633 (2005).
*
-
Boullier S, Tanguy M, Kadaoui KA, Caubet C, Sansonetti P, Corthesy B, Phalipon A. Secretory IgA-mediated neutralization of Shigella flexneri prevents intestinal tissue destruction by down-regulating inflammatory circuits.
J. Immunol. 183: 5879-5885 (2009).
-
Bouqbis L, Izaabel H, Akhayat O, Perez-Lezaun A, Calafell F, Bertranpetit J, Comas D. Association of the CTLA4 promoter region (-1661G allele) with type 1 diabetes in the South Moroccan population.
Genes Immun. 4: 132-137 (2003).
*
-
Bourdeaut F, Janoueix-Lerosey I, Lucchesi C, Paris R, Ribeiro A, de Pontual L, Amiel J, Lyonnet S, Pierron G, Michon J, Peuchmaur M, Delattre O. Cholinergic switch associated with morphological differentiation in neuroblastoma.
J. Pathol. 219: 463-472 (2009).
*
-
Bourdi M, Masubuchi Y, Reilly TP, Amouzadeh HR, Martin JL, George JW, Shah AG, Pohl LR. Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase.
Hepatology 35: 289-298 (2002).
*
-
Bourke B. Campylobacter infection: small bowel and colon.
Curr. Opin. Gastroenterol. 18: 4-9 (2002).
-
Bourlier V, Zakaroff-Girard A, Miranville A, De Barros S, Maumus M, Sengenes C, Galitzky J, Lafontan M, Karpe F, Frayn KN, Bouloumie A. Remodeling phenotype of human subcutaneous adipose tissue macrophages.
Circulation 117: 806-815 (2008).
*
-
Bourquin C, van der Haar ME, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab ME, Linington C. DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis.
Eur. J. Pharmacol. 588: 99-105 (2008).
-
Boursalian TE, McEarchern JA, Law CL, Grewal IS. Targeting CD70 for human therapeutic use.
Adv. Exp. Med. Biol. 647: 108-119 (2009).
*
-
Boursier L, Gordon JN, Thiagamoorthy S, Edgeworth JD, Spencer J. Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria.
Gastroenterology 128: 1879-1889 (2005).
*
-
Bousquet M, Gibrat C, Saint-Pierre M, Julien C, Calon F, Cicchetti F. Modulation of brain-derived neurotrophic factor as a potential neuroprotective mechanism of action of omega-3 in a parkinsonian animal model.
Prog. Neuropsychopharmacol. Biol. Psychiatry 33: 1401-1408 (2009).
-
Bouwens M, Afman LA, Muller M. Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response.
BMC Genomics 9: 262 (2008).
*
-
Bouwens M, van de Rest O, Dellschaft N, Bromhaar MG, de Groot LC, Geleijnse JM, Muller M, Afman LA. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells.
Am. J. Clin. Nutr. 90: 415-424 (2009).
*
-
Bovin LF, Brynskov J, Hegedus L, Jess T, Nielsen CH, Bendtzen K. Gene expression profiling in autoimmune diseases: chronic inflammation or disease specific patterns?
Autoimmunity 40: 191-201 (2007).
-
Bovin LF, Rieneck K, Workman C, Nielsen H, Sorensen SF, Skjodt H, Florescu A, Brunak S, Bendtzen K. Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor.
Immunol. Lett. 93: 217-226 (2004).
-
Bovo P, Mirakian R, Merigo F, Angelini G, Cavallini G, Rizzini P, Bottazzo GF, Scuro LA. HLA molecule expression on chronic pancreatitis specimens: is there a role for autoimmunity? A preliminary study.
Pancreas 2: 350-356 (1987).
-
Bowcock AM. The genetics of psoriasis and autoimmunity.
Annu. Rev. Genomics Hum. Genet. 6: 93-122 (2005).
*
-
Bowcock AM, Krueger JG. Getting under the skin: the immunogenetics of psoriasis.
Nat. Rev. Immunol. 5: 699-711 (2005).
*
-
Bowcock AM, Shannon W, Du F, Duncan J, Cao K, Aftergut K, Catier J, Fernandez-Vina MA, Menter A. Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies.
Hum. Mol. Genet. 10: 1793-1805 (2001).
*
-
Bowden K, Ridgway ND. OSBP negatively regulates ABCA1 protein stability.
J. Biol. Chem. 283: 18210-18217 (2008).
*
-
Bowen H, Biggs TE, Phillips E, Baker ST, Perry VH, Mann DA, Barton CH. c-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter.
J. Biol. Chem. 277: 34997-35006 (2002).
*
-
Bowlus CL. Chapter 11. Tumor immunology: hepatocellular carcinoma, cholangiocarcinoma, and metastatic neoplasms.
In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 137-149 (2007). *
-
Boxall S, Stanton T, Hirai K, Ward V, Yasui T, Tahara H, Tamori A, Nishiguchi S, Shiomi S, Ishiko O, Inaba M, Nishizawa Y, Dawes R, Bodmer W, Beverley PC, Tchilian EZ. Disease associations and altered immune function in CD45 138G variant carriers.
Hum. Mol. Genet. 13: 2377-2384 (2004).
*
-
Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, Herault A, Saric J, Belghiti J, Franco D, Bioulac-Sage P, Laurent-Puig P, Zucman-Rossi J. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets.
Hepatology 45: 42-52 (2007).
*
-
Boyce BF, Schwarz EM, Xing L. Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease.
Curr. Opin. Rheumatol. 18: 427-432 (2006).
-
Boyd JH, Divangahi M, Yahiaoui L, Gvozdic D, Qureshi S, Petrof BJ. Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kappaB and calcineurin.
Infect. Immun. 74: 6829-6838 (2006).
*
-
Boyd M, Bressendorff S, Møller J, Olsen J, Troelsen JT. Mapping of HNF4alpha target genes in intestinal epithelial cells.
BMC Gastroenterol. 9: 68 (2009).
*
-
Boyella VD, Nicastri AD, Bergasa NV. Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis.
Ann. Hepatol. 7: 221-226 (2008).
*
-
Boyer JL. Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease?
Gastroenterology 129: 735-740 (2005).
*
-
Boyer JL. New perspectives for the treatment of cholestasis: lessons from basic science applied clinically.
J. Hepatol. 46: 365-371 (2007).
*
-
Boyer JL, Denk G, Bohan A, Chen WS, Soroka C, Denson L. Adaptive regulation of bile salt transporters in cholestasis.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 46-47. June 18-19 (2004). *
-
Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N. Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OSTalpha-OSTbeta, in cholestasis in humans and rodents.
Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1124-G1130 (2006).
*
-
Boylan JF, Lufkin T, Achkar CC, Taneja R, Chambon P, Gudas LJ. Targeted disruption of retinoic acid receptor alpha (RAR alpha) and RAR gamma results in receptor-specific alterations in retinoic acid-mediated differentiation and retinoic acid metabolism.
Mol. Cell. Biol. 15: 843-851 (1995).
*
-
Boyle DL, Jones TL, Hammaker D, Svensson CI, Rosengren S, Albani S, Sorkin L, Firestein GS. Regulation of peripheral inflammation by spinal p38 MAP kinase in rats.
PLoS Med. 3: e338 (2006).
*
-
Boyle LH, Traherne JA, Plotnek G, Ward R, Trowsdale J. Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport.
J. Neurochem. 102: 1853-1862 (2007).
*
-
Boyton RJ, Altmann DM. Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease.
Clin. Exp. Immunol. 149: 1-8 (2007).
*
-
Boyton RJ, Reynolds C, Wahid FN, Jones MG, Ozerovitch L, Ahmad T, Chaudhry A, Jewell DP, Kon OM, Smith J, Rose M, Newman-Taylor AJ, Cole P, Wilson R, Altmann DM. IFNgamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis.
Tissue Antigens 68: 325-330 (2006).
*
-
Bozzo F, Bocca C, Colombatto S, Miglietta A. Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways.
Chem. Biol. Interact. 169: 110-121 (2007).
*
-
Braat H, Stokkers P, Hommes T, Cohn D, Vogels E, Pronk I, Spek A, van Kampen A, van Deventer S, Peppelenbosch M, Hommes D. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients.
J. Mol. Med. 83: 601-609 (2005).
*
-
Brabender J, Metzger R, Salonga D, Danenberg KD, Danenberg PV, Holscher AH, Schneider PM. Comprehensive expression analysis of retinoic acid receptors and retinoid X receptors in non-small cell lung cancer: implications for tumor development and prognosis.
Carcinogenesis 26: 525-530 (2005).
*
-
Bracken S, Byrne G, Kelly J, Jackson J, Feighery C. Altered gene expression in highly purified enterocytes from patients with active coeliac disease.
BMC Genomics 9: 377 (2008).
*
-
Braconi C, Huang N, Patel T. MicroRNA-dependent regulation of DNA methyltransferase-1 and tumor suppressor gene expression by interleukin-6 in human malignant cholangiocytes.
Hepatology Oct 19 [Epub ahead of print] (2009).
*
-
Bradford EM, Sartor MA, Gawenis LR, Clarke LL, Shull GE. Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice.
Am. J. Physiol. Gastrointest. Liver Physiol. 296: G886-G898 (2009).
*
-
Bradl M, Lassmann DH. Anti-aquaporin-4 antibodies in neuromyelitis optica: how to prove their pathogenetic relevance?
Int. MS J. 15: 75-78 (2008).
-
Bradley RL, Fisher FM, Maratos-Flier E. Dietary fatty acids differentially regulate production of TNF-alpha and IL-10 by murine 3T3-L1 adipocytes.
Obesity (Silver Spring) 16: 938-944 (2008).
*
-
Bradshaw S, Zheng WJ, Tsoi LC, Gilkeson G, Zhang XK. A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis.
Clin. Immunol. 129: 19-30 (2008).
*
-
Brady G, Farrell PJ. RUNX3-mediated repression of RUNX1 in B cells.
J. Cell Physiol. 221: 283-287 (2009).
*
-
Braegger CP, MacDonald TT. Immune mechanisms in chronic inflammatory bowel disease.
Ann. Allergy 72: 135-141 (1994).
-
Braff MH, Bardan A, Nizet V, Gallo RL. Cutaneous defense mechanisms by antimicrobial peptides.
J. Invest. Dermatol. 125: 9-13 (2005).
*
-
Brahmachari S, Jana A, Pahan K. Sodium benzoate, a metabolite of cinnamon and a food additive, reduces microglial and astroglial inflammatory responses.
J. Immunol. 183: 5917-5927 (2009).
-
Brahmachari S, Pahan K. Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis.
J. Immunol. 179: 275-283 (2007).
*
-
Brahn E, Banquerigo ML, Lee JK, Park EJ, Fogler WE, Plum SM. An angiogenesis inhibitor, 2-methoxyestradiol, involutes rat collagen-induced arthritis and suppresses gene expression of synovial vascular endothelial growth factor and basic fibroblast growth factor.
J. Rheumatol. 35: 2119-2128 (2008).
-
Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat.
Endocrinology 137: 354-366 (1996).
*
-
Brambilla R, Persaud T, Hu X, Karmally S, Shestopalov VI, Dvoriantchikova G, Ivanov D, Nathanson L, Barnum SR, Bethea JR. Transgenic inhibition of astroglial NF-kappaB improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation.
J. Immunol. 182: 2628-2640 (2009).
-
Bramlage CP, Kaps C, Ungethum U, Bramlage P, Koziolek M, Wessels J, Krenn V, Pruss A, Muller GA, Strutz F, Burmester GR, Haupl T. Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium.
Scand. J. Rheumatol. 37: 401-409 (2008).
*
-
Bramlett KS, Yao S, Burris TP. Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.
Mol. Genet. Metab. 71: 609-615 (2000).
*
-
Brancaccio D, Bommer J, Coyne D. Vitamin D receptor activator selectivity in the treatment of secondary hyperparathyroidism: understanding the differences among therapies.
Drugs 67: 1981-1998 (2007).
-
Brand A, Schonfeld E, Isharel I, Yavin E. Docosahexaenoic acid-dependent iron accumulation in oligodendroglia cells protects from hydrogen peroxide-induced damage.
J. Neurochem. 105: 1325-1335 (2008).
*
-
Brand DD, Kang AH, Rosloniec EF. Immunopathogenesis of collagen arthritis.
Springer Semin. Immunopathol. 25: 3-18 (2003).
*
-
Brand N, Petkovich M, Krust A, Chambon P, de The H, Marchio A, Tiollais P, Dejean A. Identification of a second human retinoic acid receptor.
Nature 332: 850-853 (1988).
*
-
Brand NJ, Petkovich M, Chambon P. Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha).
Nucleic Acids Res. 18: 6799-6806 (1990).
*
-
Brand OJ, Barrett JC, Simmonds MJ, Newby PR, McCabe CJ, Bruce CK, Kysela B, Carr-Smith JD, Brix T, Hunt PJ, Wiersinga WM, Hegedus L, Connell J, Wass JA, Franklyn JA, Weetman AP, Heward JM, Gough SC. Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.
Hum. Mol. Genet. 18: 1704-1713 (2009).
-
Brand S, Beigel F, Olszak T, Zitzmann K, Eichhorst ST, Otte JM, Diepolder H, Marquardt A, Jagla W, Popp A, Leclair S, Herrmann K, Seiderer J, Ochsenkuhn T, Goke B, Auernhammer CJ, Dambacher J. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration.
Am. J. Physiol. Gastrointest. Liver Physiol. 290: G827-G838 (2006).
*
-
Brand S, Dambacher J, Beigel F, Zitzmann K, Heeg MH, Weiss TS, Prufer T, Olszak T, Steib CJ, Storr M, Goke B, Diepolder H, Bilzer M, Thasler WE, Auernhammer CJ. IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1019-G1028 (2007).
*
-
Brand S, Hofbauer K, Dambacher J, Schnitzler F, Staudinger T, Pfennig S, Seiderer J, Tillack C, Konrad A, Goke B, Ochsenkuhn T, Lohse P. Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease phenotype.
Am. J. Gastroenterol. 101: 99-106 (2006).
*
-
Brandacher G, Margreiter R, Fuchs D. Implications of IFN-gamma-mediated tryptophan catabolism on solid organ transplantation.
Curr. Drug Metab. 8: 273-282 (2007).
-
Brandacher G, Perathoner A, Ladurner R, Schneeberger S, Obrist P, Winkler C, Werner ER, Werner-Felmayer G, Weiss HG, Gobel G, Margreiter R, Konigsrainer A, Fuchs D, Amberger A. Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells.
Clin. Cancer Res. 12: 1144-1151 (2006).
*
-
Brandhagen D. Can liver transplantation improve our understanding of the pathophysiology of iron overload?
Liver Transpl. 10: 1218-1220 (2004).
*
-
Brandl K, Plitas G, Mihu CN, Ubeda C, Jia T, Fleisher M, Schnabl B, Dematteo RP, Pamer EG. Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits.
Nature 455: 804-807 (2008).
*
-
Brandmaier AG, Leitner WW, Ha SP, Sidney J, Restifo NP, Touloukian CE. High-avidity autoreactive CD4+ T cells induce host CTL, overcome Tregs and mediate tumor destruction.
J. Immunother. 32: 677-688 (2009).
-
Brandtzaeg P. Nature and function of gastrointestinal antigen-presenting cells.
Allergy 56 Suppl. 67: 16-20 (2001).
-
Brandtzaeg P, Carlsen HS, Halstensen TS. The B-cell system in inflammatory bowel disease.
Adv. Exp. Med. Biol. 579: 149-167 (2006).
-
Brant SR. Exposed: the genetic underpinnings of ulcerative colitis relative to Crohn's disease.
Gastroenterology 136: 396-399 (2009).
*
-
Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.
Am. J. Hum. Genet.73: 1282-1292 (2003).
*
-
Bratke K, Goettsching H, Kuepper M, Geyer S, Luttmann W, Virchow JC. Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4(+) T cells by down-regulation of granzyme B.
Immunology 127: 338-344 (2009).
*
-
Bratland E, Bredholt G, Mellgren G, Knappskog PM, Mozes E, Husebye ES. The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: the major autoantigen in autoimmune Addison's disease.
J. Autoimmun. 33: 58-67 (2009).
-
Braun N, Fritz P, Rieth A, Schroth W, Kimmel M, Biegger D, Zakim D, Alscher MD. Predictors for treatment success and expression of glucocorticoid receptor in giant cell arteritis and polymyalgia rheumatica.
J. Rheumatol. 36: 2269-2276 (2009).
-
Braun RK, Molitor-Dart M, Wigfield C, Xiang Z, Fain SB, Jankowska-Gan E, Seroogy CM, Burlingham WJ, Wilkes DS, Brand DD, Torrealba J, Love RB. Transfer of tolerance to collagen type V suppresses T-helper-cell-17 lymphocyte-mediated acute lung transplant rejection.
Transplantation 88: 1341-1348 (2009).
-
Bravo I, Amigo L, Cohen DE, Nervi F, Rigotti A, Francone O, Zanlungo S. Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse.
Biochim. Biophys. Acta 1770: 979-988 (2007).
*
-
Brazowski E, Rozen P, Misonzhnick-Bedny F, Gitstein G. Characteristics of familial juvenile polyps expressing cyclooxygenase-2.
Am. J. Gastroenterol. 100: 130-138 (2005).
*
-
Bream JH, Ping A, Zhang X, Winkler C, Young HA. A single nucleotide polymorphism in the proximal IFN-gamma promoter alters control of gene transcription.
Genes Immun. 3: 165-169 (2002).
*
-
Breant B, Gesina E, Blondeau B. Nutrition, glucocorticoids and pancreas development.
Horm. Res. 65 Suppl. 3: 98-104 (2006).
-
Breban M, Hacquard-Bouder C, Falgarone G. Animal models of HLA-B27-associated diseases.
Curr. Mol. Med. 4: 31-40 (2004).
-
Brechot C. Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms.
Gastroenterology 127 (5 Suppl. 2): S56-S61 (2004).
*
-
Breen EC, Ignotz RA, McCabe L, Stein JL, Stein GS, Lian JB. TGF beta alters growth and differentiation related gene expression in proliferating osteoblasts in vitro, preventing development of the mature bone phenotype.
J. Cell. Physiol. 160: 323-335 (1994).
-
Bregenholt S, Brimnes J, Nissen MH, Claesson MH. In vitro activated CD4+ T cells from interferon-gamma (IFN-gamma)-deficient mice induce intestinal inflammation in immunodeficient hosts.
Clin. Exp. Immunol. 118: 228-234 (1999).
*
-
Breinig M, Caldas-Lopes E, Goeppert B, Malz M, Rieker R, Bergmann F, Schirmacher P, Mayer M, Chiosis G, Kern MA. Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma.
Hepatology 50: 102-112 (2009).
-
Breitkopf K, Sawitza I, Westhoff JH, Wickert L, Dooley S, Gressner AM. Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells.
Gut 54: 673-681 (2005).
*
-
Brem RB, Kruglyak L. The landscape of genetic complexity across 5,700 gene expression traits in yeast.
Proc. Natl. Acad. Sci. U.S.A. 102: 1572-1577 (2005).
*
-
Brendel C, Schoonjans K, Botrugno OA, Treuter E, Auwerx J. The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity.
Mol. Endocrinol. 16: 2065-2076 (2002).
*
-
Brenner D, Brechmann M, Rohling S, Tapernoux M, Mock T, Winter D, Lehmann WD, Kiefer F, Thome M, Krammer PH, Arnold R. Phosphorylation of CARMA1 by HPK1 is critical for NF-kappaB activation in T cells.
Proc. Natl. Acad. Sci. U.S.A. 106: 14508-11453 (2009).
*
-
Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y. Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia.
Proc. Natl. Acad. Sci. U.S.A. 101: 16016-16021 (2004).
*
-
Brentano F, Kyburz D, Gay S. Toll-like receptors and rheumatoid arthritis.
Methods Mol. Biol. 517: 1-15 (2009).
*
-
Brentnall TA. Ursodiol: good drug makes good.
Gastroenterology 124: 1139-1140 (2003).
*
-
Brentnall TA, Pan S, Bronner MP, Crispin DA, Mirzaei H, Cooke K, Tamura Y, Nikolskaya T, Jebailey L, Goodlett DR, McIntosh M, Aebersold R, Rabinovitch PS, Chen R. Proteins that underlie neoplastic progression of ulcerative colitis.
Proteomics Clin. Appl. 3: 1326-1337 (2009).
-
Brenzovich J, Macey M, Fernando J, Chong HJ, Barnstein B, Mirmonsef P, Morales JK, Kimura A, Cruz TD, Ryan JJ. IgE signaling suppresses FcvarepsilonRIbeta expression.
J. Leukoc. Biol. 86: 1351-1358 (2009).
*
-
Breslin NP, Todd A, Kilgallen C, O'Morain C. Monozygotic twins with Crohn's disease and ulcerative colitis: a unique case report.
Gut 41: 557-560 (1997).
*
-
Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A. Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish.
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 140: 403-407 (2005).
*
-
Breuhahn K, Baeuerle PA, Peters M, Prang N, Tox U, Kohne-Volland R, Dries V, Schirmacher P, Leo E. Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma.
Hepatol. Res. 34: 50-56 (2006).
-
Breulmann B, Bantis C, Siekierka M, Blume C, Aker S, Kuhr N, Grabensee B, Ivens K. Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation.
Clin. Transplant. 21: 615-621 (2007).
*
-
Breunis WB, van Mirre E, Geissler J, Laddach N, Wolbink G, van der Schoot E, de Haas M, de Boer M, Roos D, Kuijpers TW. Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.
Hum. Mutat. 30: E640-E650 (2009).
*
-
Brewer M, Kirkpatrick ND, Wharton JT, Wang J, Hatch K, Auersperg N, Utzinger U, Gershenson D, Bast R, Zou C. 4-HPR modulates gene expression in ovarian cells.
Int. J. Cancer 119: 1005-1013 (2006).
*
-
Briani C, Samaroo D, Alaedini A. Celiac disease: from gluten to autoimmunity.
Autoimmun. Rev. 7: 644-650 (2008).
-
Bridges KR. Iron overload and chelation therapy.
ENCYCLOPEDIA OF LIFE SCIENCES Nature Publishing Group www.els.net (2001). *
-
Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DH, Subramaniam VN, Powell LW, Anderson GJ, Ramm GA. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis.
Lancet 361: 669-673 (2003).
*
-
Briede JJ, van Delft JM, de Kok TM, van Herwijnen MH, Maas LM, Gottschalk RW, Kleinjans JC. Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in Caco-2 cells.
Toxicol. Sci. Dec 31 [Epub ahead of print] (2009).
*
-
Brigelius-Flohe R. Induction of drug metabolizing enzymes by vitamin E.
J. Plant Physiol. 162: 797-802 (2005).
-
Brigelius-Flohe R. Vitamin E and drug metabolism.
Biochem. Biophys. Res. Commun. 305: 737-740 (2003).
*
-
Briggs L, Laird K, Boss JM, Garvie CW. Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP.
Proteins 76: 655-664 (2009).
*
-
Brilot F, Geenen V. Role of viral infections in the pathogenesis of type 1 diabetes.
Rev. Med. Liege. 60: 297-302 (2005).
-
Brinckerhoff CE, Sporn MB. Retinoids and rexinoids for the 21st century: a brave new world for arthritis.
J. Rheumatol. 30: 211-213 (2003).
-
Bringer MA, Rolhion N, Glasser AL, Darfeuille-Michaud A. The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing.
J. Bacteriol. 189: 4860-4871 (2007).
*
-
Bringhurst FR. PTH receptors and apoptosis in osteocytes.
J. Musculoskelet. Neuronal Interact. 2: 245-251 (2002).
-
Brisebois M, Zehntner SP, Estrada J, Owens T, Fournier S. A pathogenic role for CD8+ T cells in a spontaneous model of demyelinating disease.
J. Immunol. 177: 2403-2411 (2006).
*
-
Briskin M, Winsor-Hines D, Shyjan A, Cochran N, Bloom S, Wilson J, McEvoy LM, Butcher EC, Kassam N, Mackay CR, Newman W, Ringler DJ. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue.
Am. J. Pathol. 151: 97-110 (1997).
*
-
Brisslert M, Bokarewa M, Larsson P, Wing K, Collins LV, Tarkowski A. Phenotypic and functional characterization of human CD25 B cells.
Immunology 117: 548-557 (2006).
*
-
Bristol JA, Morrison TE, Kenney SC. CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter.
Mol. Immunol. 46: 2706-2713 (2009).
*
-
Bristow CA, Shore P. Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ.
Nucleic Acids Res. 31: 2735-2744 (2003).
*
-
Brites D, Fernandes A, Falcao AS, Gordo AC, Silva RF, Brito MA. Biological risks for neurological abnormalities associated with hyperbilirubinemia.
J. Perinatol. 29 Suppl. 1: S8-S13 (2009).
-
Britten AC, Mijovic CH, Barnett AH, Kelly MA. Differential expression of HLA-DQ alleles in peripheral blood mononuclear cells: alleles associated with susceptibility to and protection from autoimmune type 1 diabetes.
Int. J. Immunogenet. 36: 47-57 (2009).
*
-
Brix S, Lund P, Kjaer TM, Straarup EM, Hellgren LI, Frokiaer H. CD4+ T cell activation is differentially modulated by bacteria-primed dendritic cells, but generally downregulated by n-3 polyunsaturated fatty acids.
Immunology 129: 338-350 (2010).
*
-
Broch M, Ramírez R, Auguet MT, Alcaide MJ, Aguilar C, Garcia-Espa A A, Richart C. Macrophages are novel sites of expression and regulation of retinol binding protein-4 (RBP4).
Physiol. Res. Jun 19 [Epub ahead of print] (2009).
*
-
Brockmann JG, August C, Wolters HH, Homme R, Palmes D, Baba H, Spiegel HU, Dietl KH. Sequence of reperfusion influences ischemia/reperfusion injury and primary graft function following porcine liver transplantation.
Liver Transpl. 11: 1214-1222 (2005).
*
-
Broderick G, Craddock RC, Whistler T, Taylor R, Klimas N, Unger ER. Identifying illness parameters in fatiguing syndromes using classical projection methods.
Pharmacogenomics 7: 407-419 (2006).
-
Brodin P, Karre K, Hoglund P. NK cell education: not an on-off switch but a tunable rheostat.
Trends Immunol. 30: 143-149 (2009).
*
-
Brody F, Hill S, Celenski S, Kar R, Kluk B, Pinzone J, Fu S. Expression of ectonucleotide pyrophosphate phosphodiesterase and peroxisome proliferator activated receptor gamma in morbidly obese patients.
Surg. Endosc. 21: 941-944 (2007).
*
-
Broering R, Wu J, Meng Z, Hilgard P, Lu M, Trippler M, Szczeponek A, Gerken G, Schlaak JF. Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication.
J. Hepatol. 48: 914-922 (2008).
-
Broersen K, Brink DV, Fraser G, Goedert M, Davletov B. alpha-Synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation.
Biochemistry 45: 15610-15616 (2006).
*
-
Brogan PA, Shah V, Klein N, Dillon MJ. Vbeta-restricted T cell adherence to endothelial cells: a mechanism for superantigen-dependent vascular injury.
Arthritis Rheum. 50: 589-597 (2004).
*
-
Bromley SK, Mempel TR, Luster AD. Orchestrating the orchestrators: chemokines in control of T cell traffic.
Nat. Immunol. 9: 970-980 (2008).
*
-
Bronsveld I, Mekus F, Bijman J, Ballmann M, de Jonge HR, Laabs U, Halley DJ, Ellemunter H, Mastella G, Thomas S, Veeze HJ, Tummler B. Chloride conductance and genetic background modulate the cystic fibrosis phenotype of Delta F508 homozygous twins and siblings.
J. Clin. Invest. 108: 1705-1715 (2001).
*
-
Brookes MJ, Hughes S, Turner FE, Reynolds G, Sharma N, Ismail T, Berx G, McKie AT, Hotchin N, Anderson GJ, Iqbal T, Tselepis C. A modulation of iron transport proteins in human colorectal carcinogenesis.
Gut 55: 1449-1460 (2006).
*
-
Brooks AG, Boyington JC, Sun PD. Natural killer cell recognition of HLA class I molecules.
Rev. Immunogenet. 2: 433-448 (2000).
-
Brooks WH. X chromosome inactivation and autoimmunity.
Clin. Rev. Allergy Immunol. Aug 4 [Epub ahead of print] (2009).
*
-
Brooks WH. Autoimmune disorders result from loss of epigenetic control following chromosome damage.
Med. Hypotheses 64: 590-598 (2005).
-
Brooks WH, Le Dantec C, Pers JO, Youinou P, Renaudineau Y. Epigenetics and autoimmunity.
J. Autoimmun. Jan 4 [Epub ahead of print] (2010).
-
Broom OJ, Massoumi R, Sjolander A. alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells.
J. Cell. Physiol. 209: 950-958 (2006).
*
-
Broome U, Grunewald J, Scheynius A, Olerup O, Hultcrantz R. Preferential V beta3 usage by hepatic T lymphocytes in patients with primary sclerosing cholangitis.
J. Hepatol. 26: 527-534 (1997).
*
-
Broome U, Scheynius A, Hultcrantz R. Induced expression of heat-shock protein on biliary epithelium in patients with primary sclerosing cholangitis and primary biliary cirrhosis.
Hepatology 18: 298-303 (1993).
-
Brophy CM, Luebke-Wheeler JL, Amiot BP, Khan H, Remmel RP, Rinaldo P, Nyberg SL. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function.
Hepatology 49: 578-586 (2009).
*
-
Brosi H, Reiser M, Rajasalu T, Spyrantis A, Oswald F, Boehm BO, Schirmbeck R. Processing in the endoplasmic reticulum generates an epitope on the insulin A chain that stimulates diabetogenic CD8 T cell responses.
J. Immunol. 183: 7187-7195 (2009).
-
Brouillard F, Bensalem N, Hinzpeter A, Tondelier D, Trudel S, Gruber AD, Ollero M, Edelman A. Blue native-SDS PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice.
Mol. Cell. Proteomics 4: 1762-1775 (2005).
*
-
Brousseau ME. ATP-binding cassette transporter A1, fatty acids, and cholesterol absorption.
Curr. Opin. Lipidol. 14: 35-40 (2003).
-
Brousseau ME, Hoeg JM. Transgenic rabbits as models for atherosclerosis research.
J. Lipid Res. 40: 365-375 (1999).
*
-
Brouwer E, Tervaert JW, Horst G, Huitema MG, van der Giessen M, Limburg PC, Kallenberg CG. Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders.
Clin. Exp. Immunol. 83: 379-386 (1991).
*
-
Broux B, Hellings N, Venken K, Rummens JL, Hensen K, Van Wijmeersch B, Stinissen P. Haplotype 4 of the multiple sclerosis-associated interleukin-7 receptor alpha gene influences the frequency of recent thymic emigrants.
Genes Immun. Jan 14 [Epub ahead of print] (2010).
-
Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, Manning C, Voland C, Goldring SR, Goldring MB, Libermann TA, Gravalllese EM, Oettgen P. ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation.
J. Biol. Chem. 279: 12794-12803 (2004).
*
-
Brown J, Onyango D, Ramanjaneya M, Conner A, Patel S, Dunmore S, Randeva H. Visfatin regulates insulin secretion, insulin receptor signalling and mRNA expression of diabetes related genes in mouse pancreatic beta-cells.
J. Mol. Endocrinol. Nov 11 [Epub ahead of print] (2009).
*
-
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease.
J. Biol. Chem. 279: 34674-34681 (2004).
*
-
Brown JE, Conner AC, Digby JE, Ward KL, Ramanjaneya M, Randeva HS, Dunmore SJ. Regulation of beta-cell viability and gene expression by distinct agonist fragments of adiponectin.
Peptides Feb 12 [Epub ahead of print] (2010).
*
-
Brown KL, Bylund J, Macdonald KL, Song-Zhao GX, Elliott MR, Falsafi R, Hancock RE, Speert DP. ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease.
Clin. Immunol. 129: 90-102 (2008).
*
-
Brown KS, Nackos E, Morthala S, Jensen LE, Whitehead AS, VON Feldt JM. Independent role of conventional cardiovascular risk factors as predictors of C-reactive protein concentrations in rheumatoid arthritis.
J. Rheumatol. 34: 740-746 (2007).
-
Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner.
EMBO J. 26: 3410-3422 (2007).
*
-
Brown NK, McCormick DJ, David CS, Kong YC. H2E-derived Ealpha52-68 peptide presented by H2Ab interferes with clonal deletion of autoreactive T cells in autoimmune thyroiditis.
J. Immunol. 180: 7039-7046 (2008).
*
-
Brown SJ, Abreu MT. Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease.
Curr. Opin. Drug Discov. Devel. 8: 160-168 (2005).
-
Brown TR, Stonehouse TJ, Branch JS, Brickell PM, Katz DR. Stable transfection of U937 cells with sense or antisense RXR-alpha cDNA suggests a role for RXR-alpha in the control of monoblastic differentiation induced by retinoic acid and vitamin D.
Exp. Cell Res. 236: 94-102 (1997).
*
-
Browne CD, Del Nagro CJ, Cato MH, Dengler HS, Rickert RC. Suppression of phosphatidylinositol 3,4,5-trisphosphate production is a key determinant of B cell anergy.
Immunity 31: 749-760 (2009).
-
Brozek W, Bises G, Fabjani G, Cross HS, Peterlik M. Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells.
BMC Cancer 8: 13 (2008).
*
-
Brtko J, Rock E, Nezbedova P, Krizanova O, Dvorcakova M, Minet-Quinard R, Farges MC, Ribalta J, Winklhofer-Roob BM, Vasson MP, Macejova D. Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation.
Mech. Ageing Dev. 128: 594-600 (2007).
-
Bruce KD, Cagampang FR, Argenton M, Zhang J, Ethirajan PL, Burdge GC, Bateman AC, Clough GF, Poston L, Hanson MA, McConnell JM, Byrne CD. Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression.
Hepatology 50: 1796-1808 (2009).
-
Brucet M, Marques L, Sebastian C, Lloberas J, Celada A. Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1.
Genes Immun. 5: 26-35 (2004).
*
-
Bruck R, Ashkenazi M, Weiss S, Goldiner I, Shapiro H, Aeed H, Genina O, Helpern Z, Pines M. Prevention of liver cirrhosis in rats by curcumin.
Liver Int. 27: 373-383 (2007).
*
-
Brucklacher-Waldert V, Steinbach K, Lioznov M, Kolster M, Holscher C, Tolosa E. Phenotypical characterization of human Th17 cells unambiguously identified by surface IL-17A expression.
J. Immunol. 183: 5494-5501 (2009).
-
Brudzewsky D, Pedersen AE, Claesson MH, Gad M, Kristensen NN, Lage K, Jensen T, Tommerup N, Larsen LA, Knudsen S, Tumer Z. Genome-wide gene expression profiling of SCID mice with T-cell-mediated colitis.
Scand. J. Immunol. 69: 437-446 (2009).
*
-
Bruemmer D, Law RE. Liver X receptors: potential novel targets in cardiovascular diseases.
Curr. Drug Targets Cardiovasc. Haematol. Disord. 5: 533-540 (2005).
-
Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Reed JC. PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kB and caspase-1 activation in macrophages.
J. Biol. Chem. 279: 51897-51907 (2004).
*
-
Brugman S, Liu KY, Lindenbergh-Kortleve D, Samsom JN, Furuta GT, Renshaw SA, Willemsen R, Nieuwenhuis EE. Oxazolone-induced enterocolitis in zebrafish depends on the composition of the intestinal microbiota.
Gastroenterology 137: 1757-1767.e1 (2009).
*
-
Brummelkamp T, Nijman S, Dirac A, Bernards R. High throughput loss-of-function phenotypic screens in mammalian cells.
Falk Symposium 138. XII FALK LIVER WEEK 2003 (Part III) In Honour of Hans Popper’s 100th Birthday. State-of-the-art of hepatology: Molecular and Cell Biology. Freiburg (Germany). p. 52. October 20 - 21 (2003). *
-
Brun T, Gauthier BR. A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease.
J. Mol. Endocrinol. 40: 37-45 (2008).
*
-
Brundage SI, Kirilcuk NN, Lam JC, Spain DA, Zautke NA. Insulin increases the release of proinflammatory mediators.
J. Trauma 65: 367-372 (2008).
-
Brune CW, Kim SJ, Salt J, Leventhal BL, Lord C, Cook EH Jr. 5-HTTLPR genotype-specific phenotype in children and adolescents with autism.
Am. J. Psychiatry 163: 2148-2156 (2006).
*
-
Brunelli L, Cieslik KA, Alcorn JL, Vatta M, Baldini A. Peroxisome proliferator-activated receptor-delta upregulates 14-3-3varepsilon in human endothelial cells via CCAAT/enhancer binding protein-beta.
Circ. Res. 100: e59-e71 (2007).
*
-
Brunham LR, Kruit JK, Pape TD, Parks JS, Kuipers F, Hayden MR. Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels.
Circ. Res. 99: 672-674 (2006).
*
-
Bruno L, Mazzarella L, Hoogenkamp M, Hertweck A, Cobb BS, Sauer S, Hadjur S, Leleu M, Naoe Y, Telfer JC, Bonifer C, Taniuchi I, Fisher AG, Merkenschlager M. Runx proteins regulate Foxp3 expression.
J. Exp. Med. 206: 2329-2337 (2009).
*
-
Bruno ME, Kaetzel CS. Long-term exposure of the HT-29 human intestinal epithelial cell line to TNF causes sustained up-regulation of the polymeric Ig receptor and proinflammatory genes through transcriptional and posttranscriptional mechanisms.
J. Immunol. 174: 7278-7284 (2005).
*
-
Bruno ME, West RB, Schneeman TA, Bresnick EH, Kaetzel CS. Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene.
Mol. Immunol. 40: 695-708 (2004).
*
-
Bruno R, Ferretti E, Tosi E, Arturi F, Giannasio P, Mattei T, Scipioni A, Presta I, Morisi R, Gulino A, Filetti S, Russo D. Modulation of thyroid-specific gene expression in normal and nodular human thyroid tissues from adults: an in vivo effect of thyrotropin.
J. Clin. Endocrinol. Metab. 90: 5692-5697 (2005).
*
-
Bruno R, Galastri S, Sacchi P, Cima S, Caligiuri A, Defranco R, Milani S, Gessani S, Fantuzzi L, Liotta F, Frosali F, Antonucci G, Pinzani M, Marra F. The HIV envelope protein gp120 modulates the biology of human hepatic stellate cells: a link between HIV infection and liver fibrogenesis.
Gut Sep 7 [Epub ahead of print] (2009).
-
Brunt EM, Swanson PE. Immunoreactivity for c-erbB-2 oncopeptide in benign and malignant diseases of the liver.
Am. J. Clin. Pathol. 97: S53-S61 (1992).
-
Brush MH, Shenolikar S. Control of cellular GADD34 levels by the 26S proteasome.
Mol. Cell. Biol. 28: 6989-7000 (2008).
*
-
Brusko TM, Wasserfall CH, Hulme MA, Cabrera R, Schatz D, Atkinson MA. Influence of membrane CD25 stability on T lymphocyte activity: implications for immunoregulation.
PLoS One 4: e7980 (2009).
*
-
Brustle A, Heink S, Huber M, Rosenplanter C, Stadelmann C, Yu P, Arpaia E, Mak TW, Kamradt T, Lohoff M. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4.
Nat. Immunol. 8: 958-966 (2007).
*
-
Bruwer M, Schmid KW, Senninger N, Schurmann G. Immunohistochemical expression of P53 and oncogenes in ulcerative colitis-associated colorectal carcinoma.
World J. Surg. 26: 390-396 (2002).
*
-
Bruzzese V, Pepe J. Efficacy of cyclosporine in the treatment of a case of infliximab-induced erythrodermic psoriasis.
Int. J. Immunopathol. Pharmacol. 22: 235-238 (2009).
-
Bryceson YT, March ME, Ljunggren HG, Long EO. Activation, coactivation, and costimulation of resting human natural killer cells.
Immunol. Rev. 214: 73-91 (2006).
*
-
Bryl E, Vallejo AN, Matteson EL, Witkowski JM, Weyand CM, Goronzy JJ. Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis.
Arthritis Rheum. 52: 2996-3003 (2005).
*
-
Brynedal B, Khademi M, Wallstrom E, Hillert J, Olsson T, Duvefelt K. Gene expression profiling in multiple sclerosis: a disease of the central nervous system, but with relapses triggered in the periphery?
Neurobiol. Dis. Nov 25 [Epub ahead of print] (2009).
-
Bryzgalov LO, Ershov NI, Oshchepkov DY, Kaledin VI, Merkulova TI. Detection of target genes of FOXA transcription factors involved in proliferation control.
Biochemistry (Mosc.) 73: 70-75 (2008).
-
Bsibsi M, Bajramovic JJ, Van Duijvenvoorden E, Persoon C, Ravid R, Van Noort JM, Vogt MH. Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins.
Glia 55: 473-482 (2007).
-
Bsibsi M, Persoon-Deen C, Verwer RW, Meeuwsen S, Ravid R, Van Noort JM. Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators.
Glia 53: 688-695 (2006).
-
Bu D, Tomlinson G, Lewis CM, Zhang C, Kildebeck E, Euhus DM. An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer.
Breast Cancer Res. Treat. 99: 257-265 (2006).
*
-
Bu P, Wan YJ. Fenretinide-induced apoptosis of Huh-7 hepatocellular carcinoma is retinoic acid receptor beta dependent.
BMC Cancer 7: 236 (2007).
*
-
Bu SY, Mashek MT, Mashek DG. Suppression of long chain acyl-CoA synthetase 3 (ACSL3) decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity.
J. Biol. Chem. 284: 30474-30483 (2009).
*
-
Buaud B, Esterle L, Vaysse C, Alfos S, Combe N, Higueret P, Pallet V. A high-fat diet induces lower expression of retinoid receptors and their target genes GAP-43/neuromodulin and RC3/neurogranin in the rat brain.
Br. J. Nutr. Jan 27 [Epub ahead of print] (2010).
*
-
Buch MH, Boyle DL, Rosengren S, Saleem B, Reece RJ, Rhodes LA, Radjenovic A, English A, Tang H, Vratsanos G, O'Connor P, Firestein GS, Emery P. Mode of action of abatacept in rheumatoid arthritis patients having failed TNF blockade: a histological, gene expression and dynamic MRI pilot study.
Ann. Rheum. Dis. 68: 1220-1227 (2009).
-
Buch MH, Reece RJ, Quinn MA, English A, Cunnane G, Henshaw K, Bingham SJ, Bejarano V, Isaacs J, Emery P. The value of synovial cytokine expression in predicting the clinical response to TNF antagonist therapy (infliximab).
Rheumatology (Oxford) 47: 1469-1475 (2008).
*
-
Bucher C, Jasperson L, Vogtenhuber C, Goren E, Munger M, Panoskaltsis-Mortari A, Sivakumar P, Blazar BR. IL-21 blockade reduces graft-versus-host-disease mortality by supporting inducible T regulatory cell generation.
Blood 114: 5375-5384 (2009).
*
-
Buchert M, Darido C, Lagerqvist E, Sedello A, Cazevieille C, Buchholz F, Pannequin J, Joubert D, Hollande F. The symplekin/ZONAB complex inhibits intestinal cell differentiation via the repression of AML1/Runx1.
Gastroenterology 137: 156-164.e1-e3 (2009).
*
-
Buchwald M, Sood R, Auerbach W. Regulation of expression of CFTR in human intestinal epithelial cells.
Adv. Exp. Med. Biol. 290: 241-250 (1991).
-
Buchwald PC, Westin G, Akerstrom G. Vitamin D in normal and pathological parathyroid glands: new prospects for treating hyperparathyroidism (review).
Int. J. Mol. Med. 15: 701-706 (2005).
-
Bucin D, Truedsson L, Hammarstrom L, Smith CI, Sjoholm AG. C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes.
Exp. Clin. Immunogenet. 8: 233-241 (1991).
-
Buck D, Kroner A, Rieckmann P, Maurer M, Wiendl H. Analysis of the C/T(-1)) single nucleotide polymorphism in the CD40 gene in multiple sclerosis.
Tissue Antigens 68: 335-338 (2006).
*
-
Buck I, Morceau F, Cristofanon S, Reuter S, Dicato M, Diederich M. The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation.
Int. J. Oncol. 34: 853-860 (2009).
-
Bucker R, Troeger H, Kleer J, Fromm M, Schulzke JD. Arcobacter butzleri induces barrier dysfunction in intestinal HT-29/B6 cells.
J. Infect. Dis. 200: 756-764 (2009).
*
-
Buckley DB, Klaassen CD. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of AhR, CAR, PXR, PPARalpha, and Nrf2.
Drug Metab. Dispos. 37: 847-856 (2009).
*
-
Buckley SM, Waddington S, Jezzard S, Bergau A, Themis M, Macvinish L, Cuthbert A, Colledge W, Coutelle C. Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice.
Mol. Ther. 16: 819-824 (2008).
-
Bucova M, Bernadic M, Buckingham T. C-reactive protein, cytokines and inflammation in cardiovascular diseases.
Bratisl. Lek. Listy. 109: 333-340 (2008).
-
Budagian V, Bulanova E, Orinska Z, Ludwig A, Rose-John S, Saftig P, Borden EC, Bulfone-Paus S. Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17).
J. Biol. Chem. 279: 40368-40375 (2004).
*
-
Buenafe AC, Bourdette DN. Lipopolysaccharide pretreatment modulates the disease course in experimental autoimmune encephalomyelitis.
J. Neuroimmunol. 182: 32-40 (2007).
-
Buendia MA. Liver cancer.
Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 20-21 (2006). *
-
Bueno AA, Oyama LM, de Macedo Motoyama CS, da Silva Biz CR, Silveira VL, Ribeiro EB, Oller do Nascimento CM. Long chain saturated fatty acids increase haptoglobin gene expression in C57BL/6J mice adipose tissue and 3T3-L1 cells.
Eur. J. Nutr. Oct 25 [Epub ahead of print] (2009).
*
-
Bueno AA, Oyama LM, de Oliveira C, Pisani LP, Ribeiro EB, Silveira VL, Oller do Nascimento CM. Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue.
Pflugers Arch. 455: 701-709 (2008).
*
-
Bueno MR, Daneri A, Armendariz-Borunda J. Cholestasis-induced fibrosis is reduced by interferon alpha-2a and is associated with elevated liver metalloprotease activity.
J. Hepatol. 33: 915-925 (2000).
*
-
Buetler TM. Identification of glutathione S-transferase isozymes and gamma-glutamylcysteine synthetase as negative acute-phase proteins in rat liver.
Hepatology 28: 1551-1560 (1998).
*
-
Buettner R, Parhofer KG, Woenckhaus M, Wrede CE, Kunz-Schughart LA, Scholmerich J, Bollheimer LC. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types.
J. Mol. Endocrinol. 36: 485-501 (2006).
*
-
Bugge A, Grontved L, Aagaard MM, Borup R, Mandrup S. The PPARgamma2 A/B-domain plays a gene specific role in transactivation and co-factor recruitment.
Mol. Endocrinol. 23: 794-808 (2009).
*
-
Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease.
Hepatology 42: 987-1000 (2005).
*
-
Buhler MM, Craig M, Donaghue KC, Badhwar P, Willis J, Manolios N, Tait BD, Silink M, Bennetts BH, Stewart GJ. CCR5 genotyping in an Australian and New Zealand type 1 diabetes cohort.
Autoimmunity 35: 457-461 (2002).
-
Buhler S, Di Cristofaro J, Frassati C, Basire A, Galicher V, Chiaroni J, Picard C. High levels of molecular polymorphism at the KIR2DL4 locus in French and Congolese populations: impact for anthropology and clinical studies.
Hum. Immunol. 70: 953-959 (2009).
-
Buis CI, Geuken E, Visser DS, Kuipers F, Haagsma EB, Verkade HJ, Porte RJ. Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures.
J. Hepatol. 50: 69-79 (2009).
*
-
Buis CI, van der Steege G, Visser DS, Nolte IM, Hepkema BG, Nijsten M, Slooff MJ, Porte RJ. Heme oxygenase-1 genotype of the donor is associated with graft survival after liver transplantation.
Am. J. Transplant. 8: 377-385 (2008).
-
Buisine MP, Desreumaux P, Debailleul V, Gambiez L, Geboes K, Ectors N, Delescaut MP, Degand P, Aubert JP, Colombel JF, Porchet N. Abnormalities in mucin gene expression in Crohn's disease.
Inflamm. Bowel Dis. 5: 24-32 (1999).
*
-
Buisine MP, Desreumaux P, Leteurtre E, Copin MC, Colombel JF, Porchet N, Aubert JP. Mucin gene expression in intestinal epithelial cells in Crohn's disease.
Gut 49: 544-551 (2001).
*
-
Buisine MP, Devisme L, Degand P, Dieu MC, Gosselin B, Copin MC, Aubert JP, Porchet N. Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. II. Duodenum and liver, gallbladder, and pancreas.
J. Histochem. Cytochem. 48: 1667-1676 (2000).
*
-
Buitrago-Molina LE, Pothiraju D, Lamle J, Marhenke S, Kossatz U, Breuhahn K, Manns MP, Malek N, Vogel A. Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.
Hepatology 50: 500-509 (2009).
-
Bulian P, Gaidano G, Poeta GD, Gattei V. CD49d expression in chronic lymphocytic leukemia: a prognostic parameter and a therapeutic target.
Future Oncol. 4: 355-358 (2008).
-
Bullard DC, Hu X, Adams JE, Schoeb TR, Barnum SR. p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis.
Am. J. Pathol. 170: 2001-2008 (2007).
*
-
Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis.
J. Immunol. 178: 851-857 (2007).
*
-
Bungard CI, McGivan JD. Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers.
Arch. Biochem. Biophys. 443: 53-59 (2005).
*
-
Bunger M, Hooiveld GJ, Kersten S, Muller M. Exploration of PPAR functions by microarray technology - a paradigm for nutrigenomics.
Biochim. Biophys. Acta 1771: 1046-1064 (2007).
*
-
Bunger M, van den Bosch HM, van der Meijde J, Kersten S, Hooiveld GJ, Muller M. Genome-wide analysis of PPARalpha activation in murine small intestine.
Physiol. Genomics 30: 192-204 (2007).
*
-
Buning C, Schmidt HH, Molnar T, DE Jong DJ, Fiedler T, Buhner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Buttner J, Lochs H, Witt H. Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis.
Aliment. Pharmacol. Ther. 26: 1025-1033 (2007).
*
-
Bunk R, Dittrich AM, Schulze I, Horn J, Schmolke K, Volk HD, Wahn V, Hoflich C. Rapid whole blood flow cytometric test to detect ICOS deficiency in patients with common variable immunodeficiency.
Int. Arch. Allergy Immunol. 140: 342-344 (2006).
-
Bunyaratavej N, Sila-Asna M, Bunyaratavej A. The role of vitamin K2 on osteoblastic functions by using stem cell model.
J. Med. Assoc. Thai. 92 Suppl. 5: S1-S3 (2009).
-
Bur IM, Cohen-Solal AM, Carmignac D, Abecassis PY, Chauvet N, Martin AO, van der Horst GT, Robinson IC, Maurel P, Mollard P, Bonnefont X. The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism.
J. Biol. Chem. 284: 9066-9073 (2009).
*
-
Burakoff R, Hande S, Ma J, Banks PA, Friedman S, Makrauer F, Liew CC. Differential regulation of peripheral leukocyte genes in patients with active Crohn's disease and Crohn's disease in remission.
J. Clin. Gastroenterol. Oct 12 [Epub ahead of print] (2009).
-
Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells.
J. Immunol. 178: 280-290 (2007).
*
-
Burczynski ME, Peterson RL, Twine NC, Zuberek KA, Brodeur BJ, Casciotti L, Maganti V, Reddy PS, Strahs A, Immermann F, Spinelli W, Schwertschlag U, Slager AM, Cotreau MM, Dorner AJ. Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells.
J. Mol. Diagn. 8: 51-61 (2006).
*
-
Burek CL, Rose NR. Autoimmune thyroiditis and ROS.
Autoimmun. Rev. 7: 530-537 (2008).
-
Buren M, Yamashita M, Suzuki Y, Tomino Y, Emancipator SN. Altered expression of lymphocyte homing chemokines in the pathogenesis of IgA nephropathy.
Contrib. Nephrol. 157: 50-55 (2007).
-
Burgener IA, Konig A, Allenspach K, Sauter SN, Boisclair J, Doherr MG, Jungi TW. Upregulation of Toll-like receptors in chronic enteropathies in dogs.
J. Vet. Intern. Med. 22: 553-560 (2008).
-
Burger D, Molnarfi N, Weber MS, Brandt KJ, Benkhoucha M, Gruaz L, Chofflon M, Zamvil SS, Lalive PH. Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis.
Proc. Natl. Acad. Sci. U.S.A. 106: 4355-4359 (2009).
*
-
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lutjohann D, Demattos RB, Wellington CL. ABCG1 influences brain cholesterol synthesis but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
J. Lipid Res. 49: 1254-1267 (2008).
*
-
Burgess JK, Boustany S, Moir LM, Weckmann M, Lau JY, Grafton K, Baraket M, Hansbro PM, Hansbro NG, Foster PS, Black JL, Oliver BG. Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation and hyperresponsiveness.
Am. J. Respir. Crit. Care Med. Oct 29 [Epub ahead of print] (2009).
*
-
Burgler S, Ouaked N, Bassin C, Basinski TM, Mantel PY, Siegmund K, Meyer N, Akdis CA, Schmidt-Weber CB. Differentiation and functional analysis of human T(H)17 cells.
J. Allergy Clin. Immunol. 123: 588-595, 595.e1-e7 (2009).
-
Burgos JS, Serrano-Saiz E, Sastre I, Valdivieso F. ICP47 mediates viral neuroinvasiveness by induction of TAP protein following intravenous inoculation of herpes simplex virus type 1 in mice.
J. Neurovirol. 12: 420-427 (2006).
-
Burich A, Hershberg R, Waggie K, Zeng W, Brabb T, Westrich G, Viney JL, Maggio-Price L. Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice.
Am. J. Physiol. Gastrointest. Liver Physiol. 281: G764-G778 (2001).
*
-
Burk O, Arnold KA, Geick A, Tegude H, Eichelbaum M. A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression.
Biol. Chem. 386: 503-513 (2005).
-
Burk O, Arnold KA, Nussler AK, Schaeffeler E, Efimova E, Avery BA, Avery MA, Fromm MF, Eichelbaum M. Anti-malarial artemisinin drugs induce CYP and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor.
Mol. Pharmacol. 67: 1954-1965 (2005).
*
-
Burkart KM, Barton SJ, Holloway JW, Yang IA, Cakebread JA, Cruikshank W, Little F, Jin X, Farrer LA, Clough JB, Keith TP, Holgate S, Center DM, O'Connor GT. Association of asthma with a functional promoter polymorphism in the IL16 gene.
J. Allergy Clin. Immunol. 117: 86-91 (2006).
*
-
Burke JP, Ferrante M, Dejaegher K, Watson RW, Docherty NG, De Hertogh G, Vermeire S, Rutgeerts P, D'Hoore A, Penninckx F, Geboes K, Van Assche G, O'Connell PR. Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease.
Inflamm. Bowel Dis. 14: 1197-1204 (2008).
*
-
Burke SJ, Collier JJ, Scott DK. cAMP opposes the glucose-mediated induction of the L-PK gene by preventing the recruitment of a complex containing ChREBP, HNF4alpha, and CBP.
FASEB J. 23: 2855-2865 (2009).
*
-
Burke ZD, Reed KR, Phesse TJ, Sansom OJ, Clarke AR, Tosh D. Liver zonation occurs through a beta-catenin dependent, c-Myc independent mechanism.
Gastroenterology 136: 2316-2324.e3 (2009).
*
-
Burkly LC, Michaelson JS, Hahm K, Jakubowski A, Zheng TS. TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease.
Cytokine 40: 1-16 (2007).
-
Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH. FOXP3 gene expression in a tuberculosis case contact study.
Clin. Exp. Immunol. 149: 117-122 (2007).
*
-
Burnat G, Rau T, Elshimi E, Hahn EG, Konturek PC. Bile acids induce overexpression of homeobox gene CDX-2 and vascular endothelial growth factor (VEGF) in human Barrett's esophageal mucosa and adenocarcinoma cell line.
Scand. J. Gastroenterol. 42: 1460-1465 (2007).
*
-
Burnik FS, Yalcin S. NFKB1 -94 insertion/deletion ATTG polymorphism in gastroenteropancreatic neuroendocrine tumors.
Chemotherapy 55: 381-385 (2009).
-
Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway.
Genes Dev. 19: 2331-2342 (2005).
*
-
Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation.
Biochim. Biophys. Acta 1771: 952-960 (2007).
*
-
Buroker NE, Barboza J, Huang JY. The IkappaBalpha gene is a peroxisome proliferator-activated receptor cardiac target gene.
FEBS J. 276: 3247-3255 (2009).
*
-
Buroker NE, Young ME, Wei C, Serikawa K, Ge M, Ning XH, Portman MA. The dominant negative thyroid hormone receptor beta mutant Delta337T alters peroxisome proliferator-activated receptor alpha signaling in heart.
Am. J. Physiol. Endocrinol. Metab. 292: E453-E460 (2007).
*
-
Burrage PS, Huntington JT, Sporn MB, Brinckerhoff CE. Regulation of matrix metalloproteinase gene expression by a retinoid X receptor-specific ligand.
Arthritis Rheum. 56: 892-904 (2007).
*
-
Burrage PS, Mix KS, Brinckerhoff CE. Matrix metalloproteinases: role in arthritis.
Front. Biosci. 11: 529-543 (2006).
-
Burrage PS, Schmucker AC, Ren Y, Sporn MB, Brinckerhoff CE. Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression.
Arthritis Res. Ther. 10: R139 (2008).
*
-
Burrin DG, Stoll B. Emerging aspects of gut sulfur amino acid metabolism.
Curr. Opin. Clin. Nutr. Metab. Care 10: 63-68 (2007).
-
Burt AD. Spectrum of liver pathology in immune mediated liver diseases.
J. Gastroenterol. Hepatol. 19: S353-S355 (2004). *
-
Burum-Auensen E, De Angelis PM, Schjolberg AR, Roislien J, Andersen SN, Clausen OP. Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis.
J. Clin. Pathol. 60: 1403-1408 (2007).
*
-
Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A.
Hum. Gene Ther. 17: 135-146 (2006).
-
Buschow C, Charo J, Anders K, Loddenkemper C, Jukica A, Alsamah W, Perez C, Willimsky G, Blankenstein T. In vivo imaging of an inducible oncogenic tumor antigen visualizes tumor progression and predicts CTL tolerance.
J. Immunol. Feb 8 [Epub ahead of print] (2010).
-
Busso N, Frasnelli M, Feifel R, Cenni B, Steinhoff M, Hamilton J, So A. Evaluation of protease-activated receptor 2 in murine models of arthritis.
Arthritis Rheum. 56: 101-107 (2007).
*
-
Bustamante JJ, Copple BL, Soares MJ, Dai G. Gene profiling of maternal hepatic adaptations to pregnancy.
Liver Int. Dec 22 [Epub ahead of print] (2009).
*
-
Bustamante M, Nogues X, Agueda L, Jurado S, Wesselius A, Caceres E, Carreras R, Ciria M, Mellibovsky L, Balcells S, Diez-Perez A, Grinberg D. Promoter 2 -1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck BMD in Spanish postmenopausal women.
Calcif. Tissue Int. 81: 327-332 (2007).
*
-
Butler JE, Moore MB, Presnell SR, Chan HW, Chalupny NJ, Lutz CT. Proteasome regulation of ULBP1 transcription.
J. Immunol. 182: 6600-6609 (2009).
-
Butscheid M, Hauptvogel P, Fritz P, Klotz U, Alscher D. Hepatic expression of galectin-3 and receptor for advanced glycation end products in patients with liver disease.
J. Clin. Pathol. 60: 415-418 (2007).
-
Butti E, Bergami A, Recchia A, Brambilla E, Del Carro U, Amadio S, Cattalini A, Esposito M, Stornaiuolo A, Comi G, Pluchino S, Mavilio F, Martino G, Furlan R. IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis.
Gene Ther. 15: 504-515 (2008).
-
Butura A, Nilsson K, Morgan K, Morgan TR, French SW, Johansson I, Schuppe-Koistinen I, Ingelman-Sundberg M. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model.
J. Hepatol. 50: 572-583 (2009).
-
Buxbaum JD, Georgieva L, Young JJ, Plescia C, Kajiwara Y, Jiang Y, Moskvina V, Norton N, Peirce T, Williams H, Craddock NJ, Carroll L, Corfas G, Davis KL, Owen MJ, Harroch S, Sakurai T, O'Donovan MC. Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene.
Mol. Psychiatry 13: 162-172 (2008).
-
Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, Golde T, Masliah E, R Roberts A, Bartfai T. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity.
Proc. Natl. Acad. Sci. U.S.A. 105: 2681-2686 (2008).
*
-
Buyon JP, Clancy RM, Friedman DM. Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal/foetal dyad at risk.
J. Intern. Med. 265: 653-662 (2009).
*
-
Buyse M, Radeva G, Bado A, Farinotti R. Intestinal inflammation induces adaptation of P-glycoprotein expression and activity.
Biochem. Pharmacol. 69: 1745-1754 (2005).
*
-
Buzzelli MD, Nagarajan M, Radtka JF, Shumate ML, Navaratnarajah M, Lang CH, Cooney RN. Nuclear factor kappaB mediates the inhibitory effects of tumor necrosis factor-alpha on growth hormone-inducible gene expression in liver.
Endocrinology 149: 6378-6388 (2008).
*
-
Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer.
Cancer Metastasis Rev. 23: 77-99 (2004).
*
-
Byrne AM, Foran E, Sharma R, Davies A, Mahon C, O'Sullivan J, O'Donoghue D, Kelleher D, Long A. Bile acids modulate the Golgi membrane fission process via a protein kinase Ceta and protein kinase D-dependent pathway in colonic epithelial cells.
Carcinogenesis Jan 21 [Epub ahead of print] (2010).
*
-
Byrne JA, Meara NJ, Rayner AC, Thompson RJ, Knisely AS. Lack of hepatocellular CD10 along bile canaliculi is physiologic in early childhood and persistent in Alagille syndrome.
Lab. Invest. 87: 1138-1148 (2007).
*
-
Byun HJ, Jung WW, Lee JB, Chung HY, Sul D, Kim SJ, Park CG, Choi I, Hwang KW, Chun T. An evaluation of the neonatal immune system using a Listeria infection model.
Neonatology 92: 83-90 (2007).
-
Caballero-Franco C, Keller K, De Simone C, Chadee K. The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G315-G322 (2007).
*
-
Cabbage SE, Huseby ES, Sather BD, Brabb T, Liggitt D, Goverman J. Regulatory T cells maintain long-term tolerance to myelin basic protein by inducing a novel, dynamic state of T cell tolerance.
J. Immunol. 178: 887-896 (2007).
*
-
Cable EE, Finn PD, Stebbins JW, Hou J, Ito BR, van Poelje PD, Linemeyer DL, Erion MD. Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist.
Hepatology 49: 407-417 (2009).
*
-
Cabranes A, Venderova K, de Lago E, Fezza F, Sanchez A, Mestre L, Valenti M, Garcia-Merino A, Ramos JA, Di Marzo V, Fernandez-Ruiz J. Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis.
Neurobiol. Dis. 20: 207-217 (2005).
-
Cabrelle A, Dell'aica I, Melchiori L, Carraro S, Brunetta E, Niero R, Scquizzato E, D'Intino G, Calz L, Garbisa S, Agostini C. Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease.
J. Leukoc. Biol. 83: 212-219 (2008).
*
-
Cabrero A, Alegret M, Sanchez RM, Adzet T, Laguna JC, Vazquez M. Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes.
Diabetes 50: 1883-1890 (2001).
*
-
Cabrero A, Cubero M, Llaverias G, Jove M, Planavila A, Alegret M, Sanchez R, Laguna JC, Carrera MV. Differential effects of peroxisome proliferator-activated receptor activators on the mRNA levels of genes involved in lipid metabolism in primary human monocyte-derived macrophages.
Metabolism 52: 652-657 (2003).
*
-
Cabrero A, Laguna JC, Vazquez M. Peroxisome proliferator-activated receptors and the control of inflammation.
Curr. Drug Targets Inflamm. Allergy 1: 243-248 (2002).
-
Cabrijan L, Lipozencic J, Batinac T, Lenkovic M, Stanic Zgombic Z. Influence of PUVA and UVB radiation on expression of ICAM-1 and VCAM-1 molecules in psoriasis vulgaris.
Coll. Antropol. 32 Suppl. 2: 53-56 (2008).
-
Cabrijan L, Lipozencic J, Batinac T, Peternel S, Pastar Z. The role of CD4 and CD8 lymphocytes and macrophages in psoriasis vulgaris.
Acta Dermatovenerol. Croat. 17: 162-165 (2009).
-
Cacev T, Jokic M, Loncar B, Krizanac S, Kapitanovic S. Interleukin-6-174 G/C polymorphism is not associated with IL-6 expression and susceptibility to sporadic colon cancer.
DNA Cell Biol. Feb 4 [Epub ahead of print] (2010).
-
Cacev T, Radosevic S, Spaventi R, Pavelic K, Kapitanovic S. NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer.
Gut 54: 1129-1135 (2005).
*
-
Cadoret A, Rey C, Wendum D, Elriz K, Tronche F, Holzenberger M, Housset C. IGF-1R contributes to stress-induced hepatocellular damage in experimental cholestasis.
Am. J. Pathol. 175: 627-635 (2009).
*
-
Cadoudal T, Glorian M, Massias A, Fouque F, Forest C, Benelli C. Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes.
J. Nutr. 138: 1004-1009 (2008).
*
-
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin Iv HW. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells.
Nature 456: 259-263 (2008).
*
-
Cadwell K, Patel KK, Komatsu M, Virgin HW 4th, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease.
Autophagy 5: 250-252 (2009).
-
Caglayan E, Stauber B, Collins AR, Lyon CJ, Yin F, Liu J, Rosenkranz S, Erdmann E, Peterson LE, Ross RS, Tangirala RK, Hsueh WA. Differential roles of cardiomyocyte and macrophage peroxisome proliferator-activated receptor gamma in cardiac fibrosis.
Diabetes 57: 2470-2479 (2008).
*
-
Cagnard N, Letourneur F, Essabbani A, Devauchelle V, Mistou S, Rapinat A, Decraene C, Fournier C, Chiocchia G. Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes.
Eur. Cytokine Netw. 16: 289-292 (2005).
-
Cagnin A, Taylor-Robinson SD, Forton DM, Banati RB. In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy.
Gut 55: 547-553 (2006).
*
-
Cagnin S, Biscuola M, Patuzzo C, Trabetti E, Pasquali A, Laveder P, Faggian G, Iafrancesco M, Mazzucco A, Pignatti PF, Lanfranchi G. Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries.
BMC Genomics 10: 13 (2009).
*
-
Cahan P, Li Y, Izumi M, Graubert TA. The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells.
Nat. Genet. 41: 430-437 (2009).
*
-
Cahill RJ, Foltz CJ, Fox JG, Dangler CA, Powrie F, Schauer DB. Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus.
Infect. Immun. 65: 3126-3131 (1997).
*
-
Cai G, Zhang J, Liu L, Shen Q. Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA.
J. Mol. Cell. Cardiol. 38: 593-605 (2005).
*
-
Cai H, Chen L, Wan L, Zeng L, Yang H, Li S, Li Y, Cheng J, Lu X. High-level expression of a functional humanized anti-CTLA4 single-chain variable fragment antibody in Pichia pastoris.
Appl. Microbiol. Biotechnol. 82: 41-48 (2009).
*
-
Cai L, Yin JP, Starovasnik MA, Hogue DA, Hillan KJ, Mort JS, Filvaroff EH. Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo.
Cytokine 16: 10-21 (2001).
-
Cai SY, Boyer JL. FXR: a target for cholestatic syndromes?
Expert Opin. Ther. Targets 10: 409-421 (2006).
-
Cai SY, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained.
Gastroenterology 136: 1060-1069.e4 (2009).
*
-
Cai SY, Wang L, Ballatori N, Boyer JL. Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations.
Am. J. Physiol. Gastrointest. Liver Physiol. 281: G316-G322 (2001).
*
-
Cai X, Conley SM, Nash Z, Fliesler SJ, Cooper MJ, Naash MI. Gene delivery to mitotic and postmitotic photoreceptors via compacted DNA nanoparticles results in improved phenotype in a mouse model of retinitis pigmentosa.
FASEB J. Dec 1 [Epub ahead of print] (2009).
*
-
Cai X, Wong YF, Zhou H, Xie Y, Liu ZQ, Jiang ZH, Bian ZX, Xu HX, Liu L. The comparative study of Sprague-Dawley and Lewis rats in adjuvant-induced arthritis.
Naunyn. Schmiedebergs. Arch. Pharmacol. 373: 140-147 (2006).
*
-
Cai Y, Dai T, Ao Y, Konishi T, Chuang KH, Lue Y, Chang C, Wan YJ. Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice.
Endocrinology 144: 2311-2318 (2003).
*
-
Cai Y, Konishi T, Han G, Campwala KH, French SW, Wan YJ. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways.
Eur. J. Pharm. Sci. 15: 89-96 (2002).
*
-
Cai Z, Shi Z, Sanchez A, Zhang T, Liu M, Yang J, Wang F, Zhang D. Transcriptional regulation of TLR11 gene expression in epithelial cells.
J. Biol. Chem. 284: 33088-33096 (2009).
*
-
Calabrese V, Butterfield DA, Stella AM. Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease.
Ital. J. Biochem. 52: 177-181 (2003).
-
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E. Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity.
Neurochem. Res. 33: 2444-2471 (2008).
-
Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AM, Butterfield DA. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia.
J. Neurol. Sci. 233: 145-162 (2005).
*
-
Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, Galli F, Butterfield DA. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach.
Amino Acids 25: 437-444 (2003).
*
-
Calabuig E, Salavert M. Infectious risk.
Actas Dermosifiliogr. 99 Suppl. 4: 14-22 (2008).
-
Calandria JM, Marcheselli VL, Mukherjee PK, Uddin J, Winkler JW, Petasis NA, Bazan NG. Selective survival rescue in 15-lipoxygenase-1 deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1.
J. Biol. Chem. 284: 17877-17882 (2009).
*
-
Calbo S, Delagreverie H, Arnoult C, Authier FJ, Tron F, Boyer O. Functional tolerance of CD8+ T cells induced by muscle-specific antigen expression.
J. Immunol. 181: 408-417 (2008).
*
-
Calcagno AM, Ludwig JA, Fostel JM, Gottesman MM, Ambudkar SV. Comparison of drug transporter levels in normal colon, colon cancer, and Caco-2 cells: impact on drug disposition and discovery.
Mol. Pharm. 3: 87-93 (2006).
-
Calcinaro F, Dionisi S, Marinaro M, Candeloro P, Bonato V, Marzotti S, Corneli RB, Ferretti E, Gulino A, Grasso F, De Simone C, Di Mario U, Falorni A, Boirivant M, Dotta F. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse.
Diabetologia 48: 1565-1575 (2005).
*
-
Caldarola G, De Simone C, Carbone A, Tulli A, Amerio P, Feliciani C. TNFalpha and its receptors in psoriatic skin, before and after treatment with etanercept.
Int. J. Immunopathol. Pharmacol. 22: 961-966 (2009).
-
Caldenhoven E, Liden J, Wissink S, Van de Stolpe A, Raaijmakers J, Koenderman L, Okret S, Gustafsson JA, Van der Saag PT. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids.
Mol. Endocrinol. 9: 401-412 (1995).
*
-
Calder PC. Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases.
Mol. Nutr. Food Res. 52: 885-897 (2008).
*
-
Calder PC. Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale.
Biochimie. 91: 791-795 (2009).
-
Calder PC. Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale.
Biochimie Feb 3 [Epub ahead of print] (2009).
-
Calder PC. The 2008 ESPEN Sir David Cuthbertson lecture: fatty acids and inflammation - from the membrane to the nucleus and from the laboratory bench to the clinic.
Clin. Nutr. Nov 18 [Epub ahead of print] (2009).
-
Calder PC. Dietary modification of inflammation with lipids.
Proc. Nutr. Soc. 61: 345-358 (2002).
*
-
Calder PC. n-3 Polyunsaturated fatty acids and inflammation: from molecular biology to the clinic.
Lipids 38: 343-352 (2003).
-
Calder PC. Polyunsaturated fatty acids and inflammation.
Biochem. Soc. Trans. 33: 423-427 (2005).
*
-
Calder PC. Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids.
Braz. J. Med. Biol. Res. 31: 467-490 (1998).
*
-
Calder PC. Fatty acids and gene expression related to inflammation.
Nestle Nutr. Workshop Ser. Clin. Perform. Programme 7: 19-36 (2002).
-
Calder PC, Albers R, Antoine JM, Blum S, Bourdet-Sicard R, Ferns GA, Folkerts G, Friedmann PS, Frost GS, Guarner F, Løvik M, Macfarlane S, Meyer PD, M'Rabet L, Serafini M, van Eden W, van Loo J, Vas Dias W, Vidry S, Winklhofer-Roob BM, Zhao J. Inflammatory disease processes and interactions with nutrition.
Br. J. Nutr. 101 Suppl. 1: S1-S45 (2009).
*
-
Calder PC, Dimitriadis G, Newsholme P. Glucose metabolism in lymphoid and inflammatory cells and tissues.
Curr. Opin. Clin. Nutr. Metab. Care 10: 531-540 (2007).
-
Calder PC, Yaqoob P. Omega-3 polyunsaturated fatty acids and human health outcomes.
Biofactors 35: 266-272 (2009).
-
Calder PC, Yaqoob P. Understanding omega-3 polyunsaturated fatty acids.
Postgrad. Med. 121: 148-157 (2009).
-
Calderon B, Suri A, Pan XO, Mills JC, Unanue ER. IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes.
J. Immunol. 181: 6964-6974 (2008).
*
-
Calderon TM, Eugenin EA, Lopez L, Kumar SS, Hesselgesser J, Raine CS, Berman JW. A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis: regulation of CXCL12 expression in astrocytes by soluble myelin basic protein.
J. Neuroimmunol. 177: 27-39 (2006).
-
Caldwell CC, Chen Y, Goetzmann HS, Hao Y, Borchers MT, Hassett DJ, Young LR, Mavrodi D, Thomashow L, Lau GW. Pseudomonas aeruginosa exotoxin pyocyanin causes cystic fibrosis airway pathogenesis.
Am. J. Pathol. 175: 2473-2488 (2009).
*
-
Callen DF, Baker E, Simmers RN, Seshadri R, Roninson IB. Localization of the human multiple drug resistance gene, MDR1, to 7q21.1.
Hum. Genet. 77: 142-144 (1987).
-
Calmus Y, Gane P, Rouger P, Poupon R. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid.
Hepatology 11: 12-15 (1990).
-
Calon F, Lim GP, Morihara T, Yang F, Ubeda O, Salem N Jr, Frautschy SA, Cole GM. Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease.
Eur. J. Neurosci. 22: 617-626 (2005).
*
-
Cals-Grierson MM, Ormerod AD. Nitric oxide function in the skin.
Nitric Oxide 10: 179-193 (2004).
*
-
Calura E, Cagnin S, Raffaello A, Laveder P, Lanfranchi G, Romualdi C. Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages.
BMC Genomics 9: 630 (2008).
*
-
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, Large Scale Collab Res Program IA. A network-based analysis of systemic inflammation in humans.
Nature 437: 1032-1037 (2005).
*
-
Calverley DC, Baldermann LV, Moran K, Chen NN, McFann K. Platelet FcgammaRIIA expression is associated with the alpha(2) integrin C807T gene polymorphism in type 2 diabetes.
Platelets 17: 78-83 (2006).
-
Calviello G, Di Nicuolo F, Gragnoli S, Piccioni E, Serini S, Maggiano N, Tringali G, Navarra P, Ranelletti FO, Palozza P. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway.
Carcinogenesis 25: 2303-2310 (2004).
*
-
Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, Monego G, Ranelletti FO, Palozza P. Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2.
Carcinogenesis 28: 1202-1209 (2007).
*
-
Calvisi DF, Ladu S, Hironaka K, Factor VM, Thorgeirsson SS. Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer.
J. Hepatol. 41: 815-822 (2004).
*
-
Calvisi DF, Ladu S, Pinna F, Frau M, Tomasi ML, Sini M, Simile MM, Bonelli P, Muroni MR, Seddaiu MA, Lim DS, Feo F, Pascale RM. SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis.
Gastroenterology 137: 1816-1826.e10 (2009).
*
-
Calvisi DF, Pinna F, Ladu S, Pellegrino R, Simile MM, Frau M, De Miglio MR, Tomasi ML, Sanna V, Muroni MR, Feo F, Pascale RM. Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC.
Gut 58: 679-687 (2009).
-
Calzascia T, Loh JM, Di Berardino-Besson W, Masson F, Guillaume P, Burkhardt K, Herrera PL, Dietrich PY, Walker PR. Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes.
Glia 56: 1625-1636 (2008).
-
Camacho JA, Mardach R, Rioseco-Camacho N, Ruiz-Pesini E, Derbeneva O, Andrade D, Zaldivar F, Qu Y, Cederbaum SD. Clinical and functional characterization of a human ORNT1 mutation (T32R) in the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome.
Pediatr. Res. 60: 423-429 (2006).
*
-
Camacho M, Rodriguez C, Salazar J, Martinez-Gonzalez J, Ribalta J, Escudero JR, Masana L, Vila L. Retinoic acid induces PGI-synthase expression in human endothelial cells.
J. Lipid Res. 49: 1707-1714 (2008).
*
-
Camacho-Barquero L, Villegas I, Sanchez-Calvo JM, Talero E, Sanchez-Fidalgo S, Motilva V, Alarcon de la Lastra C. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis.
Int. Immunopharmacol. 7: 333-342 (2007).
-
Camateros P, Moisan J, Henault J, De Sanctis J, Skamene E, Radzioch D. Toll-like receptors, cytokines and the immunotherapeutics of asthma.
Curr. Pharm. Des. 12: 2365-2374 (2006).
-
Camateros P, Tamaoka M, Hassan M, Marino R, Moisan J, Marion D, Guiot MC, Martin JG, Radzioch D. Chronic asthma induced airway remodeling is prevented by the Toll-like receptor 7/8 ligand S28463.
Am. J. Respir. Crit. Care Med. 175: 1241-1249 (2007).
*
-
Cameron ER, Neil JC. The Runx genes: lineage-specific oncogenes and tumor suppressors.
Oncogene 23: 4308-4314 (2004).
*
-
Cameron S, Haller F, Dudas J, Moriconi F, Gunawan B, Armbrust T, Langer C, Fuzesi L, Ramadori G. Immune cells in primary gastrointestinal stromal tumors.
Eur. J. Gastroenterol. Hepatol. 20: 327-334 (2008).
-
Camilleri M, Carlson P, McKinzie S, Grudell A, Busciglio I, Burton D, Baxter K, Ryks M, Zinsmeister AR. Genetic variation in endocannabinoid metabolism, gastrointestinal motility and sensation.
Am. J. Physiol. Gastrointest. Liver Physiol. 294: G13-G19 (2008).
*
-
Cammas L, Trensz F, Jellali A, Ghyselinck NB, Roux M, Dolle P. Retinoic acid receptor alpha (RARalpha) is not critically required for mediating retinoic acid effects in the developing mouse retina.
Invest. Ophthalmol. Vis. Sci. Jan 27 [Epub ahead of print] (2010).
-
Camoglio L, Te Velde AA, Tigges AJ, Das PK, Van Deventer SJ. Altered expression of interferon-gamma and interleukin-4 in inflammatory bowel disease.
Inflamm. Bowel Dis. 4: 285-290 (1998).
*
-
Camolotto S, Racca A, Rena V, Nores R, Patrito LC, Genti-Raimondi S, Panzetta-Dutari GM. Expression and transcriptional regulation of individual pregnancy-specific glycoprotein genes in differentiating trophoblast cells.
Placenta Jan 27 [Epub ahead of print] (2010).
-
Campagna D, Cope L, Lakkur SS, Henderson C, Laheru D, Iacobuzio-Donahue CA. Gene expression profiles associated with advanced pancreatic cancer.
Int. J. Clin. Exp. Pathol. 1: 32-43 (2008).
*
-
Campagnoli MF, Pucci A, Garelli E, Carando A, Defilippi C, Lala R, Ingrosso G, Dianzani I, Forni M, Ramenghi U. Familial tumoral calcinosis and testicular microlithiasis associated with a new mutation of GALNT3 in a white family.
J. Clin. Pathol. 59: 440-442 (2006).
*
-
Campana G, Pasini P, Roda A, Spampinato S. Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid: role of the farnesoid X receptor.
Biochem. Pharmacol. 69: 1755-1763 (2005).
*
-
Campanati A, Goteri G, Simonetti O, Ganzetti G, Giuliodori K, Giuliano A, Sabato S, Stramazzotti D, Gulini E, Dusi D, De Blasio S, Fabris G, Offidani A. Angiogenesis in psoriatic skin and its modifications after administration of etanercept: videocapillaroscopic, histological and immunohistochemical evaluation.
Int. J. Immunopathol. Pharmacol. 22: 371-377 (2009).
-
Campbell DB, Buie TM, Winter H, Bauman M, Sutcliffe JS, Perrin JM, Levitt P. Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions.
Pediatrics 123: 1018-1024 (2009).
*
-
Campbell DB, D'Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P, Persico AM. Disruption of cerebral cortex MET signaling in autism spectrum disorder.
Ann. Neurol. 62: 243-250 (2007).
-
Campbell DB, Sutcliffe JS, Ebert PJ, Militerni R, Bravaccio C, Trillo S, Elia M, Schneider C, Melmed R, Sacco R, Persico AM, Levitt P. A genetic variant that disrupts MET transcription is associated with autism.
Proc. Natl. Acad. Sci. U.S.A. 103: 16834-16839 (2006).
*
-
Campbell DJ, Ziegler SF. FOXP3 modifies the phenotypic and functional properties of regulatory T cells.
Nat. Rev. Immunol. 7: 305-310 (2007).
*
-
Campbell FC, Xu H, El-Tanani M, Crowe P, Bingham V. The Yin and Yang of vitamin D receptor (VDR) signaling in neoplastic progression: operational networks and tissue-specific growth control.
Biochem. Pharmacol. 79: 1-9 (2010).
*
-
Campbell IK, Kinkel SA, Drake SF, Nieuwenhuijze AV, Hubert FX, Tarlinton DM, Heath WR, Scott HS, Wicks IP. Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis.
Arthritis Rheum. 60: 1683-1693 (2009).
*
-
Campbell JD, Cho Y, Foster ML, Kanzler H, Kachura MA, Lum JA, Ratcliffe MJ, Sathe A, Leishman AJ, Bahl A, McHale M, Coffman RL, Hessel EM. CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans.
J. Clin. Invest. 119: 2564-2576 (2009).
*
-
Campbell JJ, Murphy KE, Kunkel EJ, Brightling CE, Soler D, Shen Z, Boisvert J, Greenberg HB, Vierra MA, Goodman SB, Genovese MC, Wardlaw AJ, Butcher EC, Wu L. CCR7 expression and memory T cell diversity in humans.
J. Immunol. 166: 877-884 (2001).
*
-
Campbell JS, Hughes SD, Gilbertson DG, Palmer TE, Holdren MS, Haran AC, Odell MM, Bauer RL, Ren HP, Haugen HS, Yeh MM, Fausto N. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma.
Proc. Natl. Acad. Sci. U.S.A. 102: 3389-3394 (2005).
*
-
Campbell KL, Makar KW, Kratz M, Foster-Schubert KE, McTiernan A, Ulrich CM. A pilot study of sampling subcutaneous adipose tissue to examine biomarkers of cancer risk.
Cancer Prev. Res. (Phila. Pa) 2: 37-42 (2009).
-
Campbell PW 3rd, Phillips JA 3rd. The cystic fibrosis gene and relationships to clinical status.
Semin. Respir. Infect. 7: 150-157 (1992).
-
Campbell S, Michaelson J, Burkly L, Putterman C. The role of TWEAK/Fn14 IN the pathogenesis of inflammation and systemic autoimmunity.
Front. Biosci. 9: 2273-2284 (2004).
-
Campese AF, Grazioli P, Colantoni S, Anastasi E, Mecarozzi M, Checquolo S, De Luca G, Bellavia D, Frati L, Gulino A, Screpanti I. Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells.
Int. Immunol. 21: 727-743 (2009).
-
Campo GM, Avenoso A, Campo S, D'Ascola A, Traina P, Sama D, Calatroni A. Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes.
J. Cell. Biochem. 106: 83-92 (2009).
*
-
Campo I, Morbini P, Zorzetto M, Tinelli C, Brunetta E, Villa C, Bombieri C, Cuccia M, Agostini C, Bozzi V, Facoetti A, Ferrarotti I, Mazzola P, Scabini R, Semenzato G, Pignatti PF, Pozzi E, Luisetti M. Expression of receptor for advanced glycation end products in sarcoid granulomas.
Am. J. Respir. Crit. Care Med. 175: 498-506 (2007).
*
-
Campoli M, Ferrone S. Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands.
Tissue Antigens 72: 321-334 (2008).
*
-
Canale-Zambrano JC, Poffenberger MC, Cory SM, Humes DG, Haston CK. Intestinal phenotype of variable-weight cystic fibrosis knockout mice.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G222-G229 (2007).
*
-
Canaple L, Rambaud J, Dkhissi-Benyahya O, Rayet B, Tan NS, Michalik L, Delaunay F, Wahli W, Laudet V. Reciprocal regulation of BMAL1 and PPARalpha defines a novel positive feedback loop in the rodent liver circadian clock.
Mol. Endocrinol. 20: 1715-1727 (2006).
*
-
Canbay A, Feldstein A, Baskin-Bey E, Bronk SF, Gores GJ. The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse.
J. Pharmacol. Exp. Ther. 308: 1191-1196 (2004).
*
-
Cancino-Diaz JC, Reyes-Maldonado E, Banuelos-Panuco CA, Jimenez-Zamudio L, Garcia-Latorre E, Leon-Dorantes G, Blancas-Gonzalez F, Paredes-Cabrera G, Cancino-Diaz ME. Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein.
J. Invest. Dermatol. 119: 1114-1120 (2002).
*
-
Cane G, Moal VL, Pages G, Servin AL, Hofman P, Vouret-Craviari V. Up-regulation of intestinal vascular endothelial growth factor by Afa/Dr diffusely adhering Escherichia coli.
PLoS ONE 2: e1359 (2007).
*
-
Canedo P, Corso G, Pereira F, Lunet N, Suriano G, Figueiredo C, Pedrazzani C, Moreira H, Barros H, Carneiro F, Seruca R, Roviello F, Machado JC. The interferon gamma receptor 1 (IFNGR1) -56C/T gene polymorphism is associated with increased risk of early gastric carcinoma.
Gut 57: 1504-1508 (2008).
-
Canestro C, Catchen JM, Rodriguez-Mari A, Yokoi H, Postlethwait JH. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes.
PLoS Genet. 5: e1000496 (2009).
*
-
Canete JD, Santiago B, Cantaert T, Sanmarti R, Palacin A, Celis R, Graell E, Gil-Torregrosa B, Baeten D, Pablos JL. Ectopic lymphoid neogenesis in psoriatic arthritis.
Ann. Rheum. Dis. 66: 720-726 (2007).
*
-
Canny G, Cario E, Lennartsson A, Gullberg U, Brennan C, Levy O, Colgan SP. Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein.
Am. J. Physiol. Gastrointest. Liver Physiol. 290: G557-G567 (2006).
*
-
Canny G, Colgan SP. Events at the host-microbial interface of the gastrointestinal tract. I. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein.
Am. J. Physiol. Gastrointest. Liver Physiol. 288: G593-G597 (2005).
*
-
Cansell MS, Battin A, Degrace P, Gresti J, Clouet P, Combe N. Early dissimilar fates of liver eicosapentaenoic acid in rats fed liposomes or fish oil and gene expression related to lipid metabolism.
Lipids 44: 237-247 (2009).
-
Cantaert T, van Baarsen LG, Wijbrandts CA, Thurlings RM, van de Sande MG, Bos C, van der Pouw TK, Verweij CL, Tak PP, Baeten DL. Type I interferons have no major influence on humoral autoimmunity in rheumatoid arthritis.
Rheumatology (Oxford) 49: 156-166 (2010).
-
Cantarini MC, de la Monte SM, Pang M, Tong M, D'Errico A, Trevisani F, Wands JR. Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms.
Hepatology 44: 446-457 (2006).
*
-
Cantin AM, Bilodeau G, Ouellet C, Liao J, Hanrahan JW. Oxidant stress suppresses CFTR expression.
Am. J. Physiol. Cell. Physiol. 290: C262-C270 (2006).
*
-
Cantin AM, Hanrahan JW, Bilodeau G, Ellis L, Dupuis A, Liao J, Zielenski J, Durie P. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers.
Am. J. Respir. Crit. Care Med. 173: 1139-1144 (2006).
*
-
Canto E, Rodriguez-Sanchez JL, Vidal S. Naive CD4+ cells from cord blood can generate competent Th effector cells.
Transplantation 80: 850-858 (2005).
-
Canton RF, Peijnenburg AA, Hoogenboom RL, Piersma AH, van der Ven LT, van den Berg M, Heneweer M. Subacute effects of hexabromocyclododecane (HBCD) on hepatic gene expression profiles in rats.
Toxicol. Appl. Pharmacol. 231: 267-272 (2008).
*
-
Cantorna MT, Nashold FE, Hayes CE. Vitamin A deficiency results in a priming environment conducive for Th1 cell development.
Eur. J. Immunol. 25: 1673-1679 (1995).
-
Cany J, Avril A, Pichard V, Aubert D, Ferry N, Conchon S. A transgenic mouse with beta-galactosidase as a fetal liver self-antigen for immunotherapy studies.
J. Hepatol. 47: 396-403 (2007).
*
-
Cao D, Kevala K, Kim J, Moon HS, Jun SB, Lovinger D, Kim HY. Docosahexaenoic acid promotes hippocampal neuronal development and synaptic function.
J. Neurochem. 111: 510-521 (2009).
-
Cao G, Bales KR, Demattos RB, Paul SM. Liver X receptor-mediated gene regulation and cholesterol homeostasis in brain: relevance to Alzheimer's disease therapeutics.
Curr. Alzheimer Res. 4: 179-184 (2007).
-
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC. Phospholipid transfer protein is regulated by liver X receptors in vivo.
J. Biol. Chem. 277: 39561-39565 (2002).
*
-
Cao H, Kabaroff LC, You Q, Rodriguez A, Boermans HJ, Karrow NA. Characterization of ovine hepatic gene expression profiles in response to Escherichia coli lipopolysaccharide using a bovine cDNA microarray.
BMC Vet. Res. 2: 34 (2006).
*
-
Cao H, Liu H, Wu ZY. Effects of combined immune therapy on survival and Th1/Th2 cytokine balance in rat orthotopic liver transplantation.
Chin. Med. J. (Engl.) 120: 1809-1812 (2007).
-
Cao J, Li JL, Li D, Tobin JF, Gimeno RE. Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis.
Proc. Natl. Acad. Sci. U.S.A. 103: 19695-19700 (2006).
*
-
Cao J, Liu FX, Yu MX. Expression of programmed death 1 and its ligands in the liver of autoimmune hepatitis C57BL/6 mice.
Chin. Med. J. (Engl.) 122: 1941-1946 (2009).
-
Cao K, Liu W, Nakamura H, Enomoto H, Yamamoto T, Saito M, Imanishi H, Shimomura S, Cao P, Nishiguchi S. Vitamin K2 downregulates the expression of fibroblast growth factor receptor 3 in human hepatocellular carcinoma cells.
Hepatol. Res. 39: 1108-1117 (2009).
*
-
Cao L, Xu X, Cao LL, Wang RH, Coumoul X, Kim SS, Deng CX. Absence of full-length Brca1 sensitizes mice to oxidative stress, and carcinogen-induced tumorigenesis in the esophagus and forestomach.
Carcinogenesis 28: 1401-1407 (2007).
*
-
Cao LQ, Chen XL, Wang Q, Huang XH, Zhen MC, Zhang LJ, Li W, Bi J. Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells.
Acta Pharmacol. Sin. 28: 879-887 (2007).
*
-
Cao M, Cao P, Yan H, Lu W, Ren F, Hu Y, Zhang S. Construction, purification, and characterization of anti-BAFF scFv-Fc fusion antibody expressed in CHO/dhfr(-) cells.
Appl. Biochem. Biotechnol. 157: 562-574 (2009).
*
-
Cao P, Zhang S, Fang Z, Huang H, Bai P, Zhang Q, Luo C. Generation of a fusion protein of the extracellular domain of BR3 with the Fc fragment of human IgG1 (sBR3-Fc) in Pichia pastoris as an antagonist for BLyS.
Appl. Microbiol. Biotechnol. 78: 275-282 (2008).
*
-
Cao WM, Murao K, Imachi H, Yu X, Dobashi H, Yoshida K, Muraoka T, Kotsuna N, Nagao S, Wong NC, Ishida T. Insulin like growth factor-I regulation of hepatic scavenger receptor class BI.
Endocrinology 145: 5540-5547 (2004).
*
-
Cao Y, Brombacher F, Tunyogi-Csapo M, Glant TT, Finnegan A. Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response.
Arthritis Rheum. 56: 861-870 (2007).
*
-
Cao Y, Jia SF, Chakravarty G, de Crombrugghe B, Kleinerman ES. The osterix transcription factor down-regulates interleukin-1 alpha expression in mouse osteosarcoma cells.
Mol. Cancer Res. 6: 119-126 (2008).
*
-
Caohuy H, Jozwik C, Pollard HB. Rescue of deltaf508-CFTR by the SGK1/NEDD4-2 signaling pathway.
J. Biol. Chem. 284: 25241-25253 (2009).
*
-
Capeau J. The story of adiponectin and its receptors AdipoR1 and R2: to follow.
J. Hepatol. 47: 736-738 (2007).
-
Capelli A, Di Stefano A, Gnemmi I, Donner CF. CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis.
Eur. Respir. J. 25: 701-707 (2005).
*
-
Capello A, Moons LM, Van de Winkel A, Siersema PD, van Dekken H, Kuipers EJ, Kusters JG. Bile acid-stimulated expression of the farnesoid X receptor enhances the immune response in Barrett esophagus.
Am. J. Gastroenterol. 103: 1510-1516 (2008).
*
-
Capocasale RJ, Makropoulos DA, Achuthanandam R, Stowell N, Quinn J, Rafferty PA, O'Brien J, Emmell E, Bugelski PJ. Myelodysplasia and anemia of chronic disease in human tumor necrosis factor-alpha transgenic mice.
Cytometry A. 73: 148-159 (2008).
-
Capon F, Allen MH, Ameen M, Burden AD, Tillman D, Barker JN, Trembath RC. A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups.
Hum. Mol. Genet. 13: 2361-2368 (2004).
*
-
Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene.
Hum. Mol. Genet. 17: 1938-1945 (2008).
*
-
Caponi L, Petit-Teixeira E, Sebbag M, Bongiorni F, Moscato S, Pratesi F, Pierlot C, Osorio J, Chapuy-Regaud S, Guerrin M, Cornelis F, Serre G, Migliorini P; ECRAF. A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population.
Ann. Rheum. Dis. 64: 587-593 (2005).
*
-
Caprilli R. Why does Crohn's disease usually occur in terminal ileum?
Journal of Crohn's and Colitis 2: 352-356 (2008).
-
Caprioli F, Pallone F, Monteleone G. Th17 immune response in IBD: a new pathogenic mechanism.
Journal of Crohn's and Colitis 2: 291-295 (2008).
-
Caprioli F, Sarra M, Caruso R, Stolfi C, Fina D, Sica G, Macdonald TT, Pallone F, Monteleone G. Autocrine regulation of IL-21 production in human T lymphocytes.
J. Immunol. 180: 1800-1807 (2008).
*
-
Capsoni F, Sarzi-Puttini P, Atzeni F, Minonzio F, Bonara P, Doria A, Carrabba M. Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis.
Arthritis Res. Ther. 7: R250-R255 (2005).
*
-
Capuano P, Bacic D, Stange G, Hernando N, Kaissling B, Pal R, Kocher O, Biber J, Wagner CA, Murer H. Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1.
Pflugers Arch. 449: 392-402 (2005).
*
-
Caputo CB, Salama AI. The amyloid proteins of Alzheimer's disease as potential targets for drug therapy.
Neurobiol. Aging 10: 451-461 (1989).
-
Caputo M, Eletto D, Torino G, Tecce MF. Cooperation of docosahexaenoic acid and vitamin E in the regulation of UDP-glucuronosyltransferase mRNA expression.
J. Cell Physiol. 215: 765-770 (2008).
*
-
Caraccio N, Cuccato S, Pratesi F, Dardano A, Ursino S, Chimenti D, Boldrini L, Materazzi G, Migliorini P, Monzani F. Effect of type I interferon(s) on cell viability and apoptosis in primary human thyrocyte cultures.
Thyroid 19: 149-155 (2009).
-
Caraceni P, Pertosa A, Giannone F, Domenicali M, Grattagliano I, Perrelli MG, Principe A, Cutrin J, Croci T, Bernardi M. Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischemia-reperfusion injury complicated by endotoxemia.
Gut 58: 1135-1143 (2009).
-
Caramia G. Omega-3: from cod-liver oil to nutrigenomics.
Minerva Pediatr. 60: 443-455 (2008).
-
Carayol N, Chen J, Yang F, Jin T, Jin L, States D, Wang CY. A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression.
J. Biol. Chem. 281: 31142-31151 (2006).
*
-
Carbone J, Sarmiento E, Micheloud D, Rodriguez-Molina J, Fernandez-Cruz E. Elevated levels of activated CD4 T cells in common variable immunodeficiency: association with clinical findings.
Allergol. Immunopathol. (Madr.) 34: 131-135 (2006).
-
Cardoso CR, Provinciatto PR, Godoi DF, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. IL-4 regulates susceptibility to intestinal inflammation in murine food allergy.
Am. J. Physiol. Gastrointest. Liver Physiol. 296: G593-G600 (2009).
*
-
Cardoso CR, Provinciatto PR, Godoi DF, Vieira TS, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. B cells are involved in the modulation of pathogenic gut immune response in food-allergic enteropathy.
Clin. Exp. Immunol. 154: 153-161 (2008).
*
-
Cardoso FC, Macedo GC, Gava E, Kitten GT, Mati VL, de Melo AL, Caliari MV, Almeida GT, Venancio TM, Verjovski-Almeida S, Oliveira SC. Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection.
PLoS Negl. Trop. Dis. 2: e308 (2008).
*
-
Careccia S, Mainardi S, Pelosi A, Gurtner A, Diverio D, Riccioni R, Testa U, Pelosi E, Piaggio G, Sacchi A, Lavorgna S, Lo-Coco F, Blandino G, Levrero M, Rizzo MG. A restricted signature of miRNAs distinguishes APL blasts from normal promyelocytes.
Oncogene 28: 4034-4040 (2009).
*
-
Carey AH, Waterworth D, Patel K, White D, Little J, Novelli P, Franks S, Williamson R. Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17.
Hum. Mol. Genet. 3: 1873-1876 (1994).
-
Carey AL, Petersen EW, Bruce CR, Southgate RJ, Pilegaard H, Hawley JA, Pedersen BK, Febbraio MA. Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion.
Diabetologia 49: 1000-1007 (2006).
*
-
Carey HV, Martin SL. Preservation of intestinal gene expression during hibernation.
Am. J. Physiol. 271: G804-G813 (1996).
-
Carey R, Jurickova I, Ballard E, Bonkowski E, Han X, Xu H, Denson LA. Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease.
Inflamm. Bowel Dis. 14: 446-457 (2008).
*
-
Cariello NF, Romach EH, Colton HM, Ni H, Yoon L, Falls JG, Casey W, Creech D, Anderson SP, Benavides GR, Hoivik DJ, Brown R, Miller RT. Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver.
Toxicol. Sci. 88: 250-264 (2005).
*
-
Cario E. Toll-like receptors and gastrointestinal diseases: from bench to bedside?
Curr. Opin. Gastroenterol. 18: 696-704 (2002).
-
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease.
Infect. Immun. 68: 7010-7017 (2000).
*
-
Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B. FXR-deficiency confers increased susceptibility to torpor.
FEBS Lett. 581: 5191-5198 (2007).
*
-
Carissimi C, Fulci V, Macino G. MicroRNAs: novel regulators of immunity.
Autoimmun. Rev. 8: 520-524 (2009).
-
Carl JW, Bai XF. IL27: its roles in the induction and inhibition of inflammation.
Int. J. Clin. Exp. Pathol. 1: 117-123 (2008).
*
-
Carl VS, Brown-Steinke K, Nicklin MJ, Smith MF Jr. Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages.
J. Biol. Chem. 277: 17448-17456 (2002).
*
-
Carlberg C, Dunlop TW. The impact of chromatin organization of vitamin D target genes.
Anticancer Res. 26: 2637-2645 (2006).
-
Carlberg C, Dunlop TW. An integrated biological approach to nuclear receptor signaling in physiological control and disease.
Crit. Rev. Eukaryot. Gene Expr. 16: 1-22 (2006).
-
Carlen L, Sakuraba K, Stahle M, Sanchez F. HLA-C expression pattern is spatially different between psoriasis and eczema skin lesions.
J. Invest. Dermatol. 127: 342-348 (2007).
*
-
Carlen LM, Sanchez F, Bergman AC, Becker S, Hirschberg D, Franzen B, Coffey J, Jornvall H, Auer G, Alaiya AA, Stahle M. Proteome analysis of skin distinguishes acute guttate from chronic plaque psoriasis.
J. Invest. Dermatol. 124: 63-69 (2005).
*
-
Carless M. Investigation of genomic methylation status using methylation-specific and bisulfite sequencing polymerase chain reaction.
Methods Mol. Biol. 523: 1-18 (2009).
-
Carlos Moraes Dos Santos D, da Silva Gomes Martinho JM, Pacheco-Moreira LF, Carvalho Viana de Araujo C, Caroli-Bottino A, Pannain VL, Soares Trinta K, Gandini M, da Costa Neves PC, de Souza Matos DC, Goncalves Caputo LF, Pelajo-Machado M, Alves Pinto M. Eosinophils involved in fulminant hepatic failure are associated with high interleukin-6 expression and absence of interleukin-5 in liver and peripheral blood.
Liver Int. 29: 544-551 (2009).
*
-
Carlsen M, Cilio CM. Normal T cell development in the absence of thymic insulin expression.
Ann. N. Y. Acad. Sci. 1079: 205-212 (2006).
*
-
Carlson CS, Heagerty PJ, Nord AS, Pritchard DK, Ranchalis J, Boguch JM, Duan H, Hatsukami TS, Schwartz SM, Rieder MJ, Nickerson DA, Jarvik GP. TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects.
Hum. Genet. 121: 65-75 (2007).
*
-
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R. Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation - protective role of Mediterranean diet polyphenolic antioxidants.
Am. J. Physiol. Heart Circ. Physiol. 293: H2344-H2354 (2007).
*
-
Carmel JF, Tarnus E, Cohn JS, Bourdon E, Davignon J, Bernier L. High expression of apolipoprotein E impairs lipid storage and promotes cell proliferation in human adipocytes.
J. Cell. Biochem. 106: 608-617 (2009).
*
-
Carmel L, Efroni S, White PD, Aslakson E, Vollmer-Conna U, Rajeevan MS. Gene expression profile of empirically delineated classes of unexplained chronic fatigue.
Pharmacogenomics 7: 375-386 (2006).
-
Carmody RJ, Ruan Q, Liou HC, Chen YH. Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells.
J. Immunol. 178: 186-191 (2007).
*
-
Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Penicaud L. S 26948, a new specific PPARgamma modulator (SPPARM) with potent antidiabetic and antiatherogenic effects.
Diabetes 56: 2797-2808 (2007).
*
-
Carnahan VE, Redinbo MR. Structure and function of the human nuclear xenobiotic receptor PXR.
Curr. Drug Metab. 6: 357-367 (2005).
-
Carneiro Pdos S, Peters LC, Vorraro F, Borrego A, Ribeiro OG, Starobinas N, Jensen JR, Cabrera WH, Ibanez OM, De Franco M. Gene expression profiles of bone marrow cells from mice phenotype-selected for maximal or minimal acute inflammations: searching for genes in acute inflammation modifier loci.
Immunology 128: e562-e571 (2009).
-
Carney G, Wei S, Rizzo WB. Sjogren-Larsson syndrome: seven novel mutations in the fatty aldehyde dehydrogenase gene ALDH3A2.
Hum. Mutat. 24: 186 (2004).
*
-
Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P. Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.
J. Biol. Chem. 284: 921-929 (2009).
*
-
Carol M, Borruel N, Antolin M, Llopis M, Casellas F, Guarner F, Malagelada JR. Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease.
J. Leukoc. Biol. 79: 917-922 (2006).
*
-
Carpentino JE, Hynes MJ, Appelman HD, Zheng T, Steindler DA, Scott EW, Huang EH. Aldehyde dehydrogenase-expressing colon stem cells contribute to tumorigenesis in the transition from colitis to cancer.
Cancer Res. 69: 8208-8215 (2009).
*
-
Carr DF, Alfirevic A, Tugwood JD, Barratt BJ, Sherwood J, Smith J, Pirmohamed M, Kevin Park B. Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity.
Pharmacogenet. Genomics 17: 961-972 (2007).
-
Carr WH, Pando MJ, Parham P. KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand.
J. Immunol. 175: 5222-5229 (2005).
*
-
Carr WH, Rosen DB, Arase H, Nixon DF, Michaelsson J, Lanier LL. Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation.
J. Immunol. 178: 647-651 (2007).
*
-
Carretero M, Escamez MJ, Garcia M, Duarte B, Holguin A, Retamosa L, Jorcano JL, Rio MD, Larcher F. In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37.
J. Invest. Dermatol. 128: 223-236 (2008).
*
-
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity.
J. Immunol. 178: 172-178 (2007).
*
-
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice.
J. Immunol. 178: 179-185 (2007).
*
-
Carrillo-Lopez N, Alvarez-Hernandez D, Gonzalez-Suarez I, Roman-Garcia P, Valdivielso JM, Fernandez-Martin JL, Cannata-Andia JB. Simultaneous changes in the calcium-sensing receptor and the vitamin D receptor under the influence of calcium and calcitriol.
Nephrol. Dial. Transplant. 23: 3479-3484 (2008).
-
Carrington M, Kissner T, Gerrard B, Ivanov S, O'Brien SJ, Dean M. Novel alleles of the chemokine-receptor gene CCR5.
Am. J. Hum. Genet. 61: 1261-1267 (1997).
*
-
Carrington M, Martin MP. The impact of variation at the KIR gene cluster on human disease.
Curr. Top. Microbiol. Immunol. 298: 225-257 (2006).
-
Carroll JM, Crompton T, Seery JP, Watt FM. Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss.
J. Invest. Dermatol. 108: 412-422 (1997).
-
Carroll MC, Prodeus AP. Linkages of innate and adaptive immunity.
Curr. Opin. Immunol. 10: 36-40 (1998).
-
Carta M, Stancampiano R, Tronci E, Collu M, Usiello A, Morelli M, Fadda F. Vitamin A deficiency induces motor impairments and striatal cholinergic dysfunction in rats.
Neuroscience 139: 1163-1172 (2006).
*
-
Carter BA, Prendergast DR, Taylor OA, Zimmerman TL, Furstenberg RV, Moore DD, Karpen SJ. Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR.
Pediatr. Res. 62: 301-306 (2007).
*
-
Carter CJ. Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis.
Neurochem. Int. 50: 12-38 (2007).
-
Carter JC, Church FC. Obesity and breast cancer: the roles of peroxisome proliferator-activated receptor-gamma and plasminogen activator inhibitor-1.
PPAR Res. 2009: 345320 (2009).
*
-
Carter MJ, Jones S, Camp NJ, Cox A, Mee J, Warren B, Duff GW, Lobo AJ, Di Giovine FS. Functional correlates of the interleukin-1 receptor antagonist gene polymorphism in the colonic mucosa in ulcerative colitis.
Genes Immun. 5: 8-15 (2004).
*
-
Cartier KC, Miscimarra L, Dazard JE, Song Y, Iyengar SK, Rao JS. Studying genetic determinants of natural variation in human gene expression using Bayesian ANOVA.
BMC Proc. 1 Suppl. 1: S115 (2007).
*
-
Carty M, Goodbody R, Schroder M, Stack J, Moynagh PN, Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling.
Nat. Immunol. 7: 1074-1081 (2006).
*
-
Carvajal K, Hernandez-Esquivel Mde L, Moreno-Sanchez R. PPARs, metabolic syndrome and cardiac diseases.
Arch. Cardiol. Mex. 77 Suppl. 4: S4-S66-S76 (2007).
-
Carvalho B, Postma C, Mongera S, Hopmans E, Diskin S, van de Wiel MA, van Criekinge W, Thas O, Matthai A, Cuesta MA, Droste JS, Craanen ME, Schrock E, Ylstra B, Meijer GA. Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression.
Gut 58: 79-89 (2009).
*
-
Carvalho LS, Correa H, Silva GC, Campos FS, Baiao FR, Ribeiro LS, Faria AM, d'Avila Reis D. May genetic factors in fibromyalgia help to identify patients with differentially altered frequencies of immune cells?
Clin. Exp. Immunol. 154: 346-352 (2008).
*
-
Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Nat. Genet. 41: 619-624 (2009).
*
-
Casas R, Lindau C, Zetterstrom O, Duchen K. Downregulation of CXCR6 and CXCR3 in lymphocytes from birch-allergic patients.
Scand. J. Immunol. 68: 351-361 (2008).
*
-
Casciola-Rosen L, Miagkov A, Nagaraju K, Askin F, Jacobson L, Rosen A, Drachman DB. Granzyme B: evidence for a role in the origin of myasthenia gravis.
J. Neuroimmunol. 201-202: 33-40 (2008).
-
Casellas F, Antoln M, Varela E, Garca-Lafuente A, Guarner F, Borruel N, Armengol Miro JR, Malagelada JR. Fecal excretion of human deoxyribonucleic acid as an index of inflammatory activity in ulcerative colitis.
Clin. Gastroenterol. Hepatol. 2: 683-689 (2004).
*
-
Caserta TM, Knisley AA, Tan FK, Arnett FC, Brown TL. Genotypic analysis of the TGF beta-509 allele in patients with systemic lupus erythematosus and Sjogren's syndrome.
Ann. Genet. 47: 359-363 (2004).
-
Casey WM, Brodie T, Yoon L, Ni H, Jordan HL, Cariello NF. Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X.
Biomarkers 13: 364-376 (2008).
-
Cash H, Relle M, Menke J, Brochhausen C, Jones SA, Topley N, Galle PR, Schwarting A. Interleukin 6 (IL-6) deficiency delays lupus nephritis in MRL-Faslpr mice: the IL-6 pathway as a new therapeutic target in treatment of autoimmune kidney disease in systemic lupus erythematosus.
J. Rheumatol. Dec 1 [Epub ahead of print] (2009).
-
Cash HL, Whitham CV, Hooper LV. Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli.
Protein Expr. Purif. 48: 151-159 (2006).
*
-
Cassani B, Poliani PL, Moratto D, Sobacchi C, Marrella V, Imperatori L, Vairo D, Plebani A, Giliani S, Vezzoni P, Facchetti F, Porta F, Notarangelo LD, Villa A, Badolato R. Defect of regulatory T cells in patients with Omenn syndrome.
J. Allergy Clin. Immunol. 125: 209-216 (2010).
*
-
Cassatella MA, da Silva GP, Tinazzi I, Facchetti F, Scapini P, Calzetti F, Tamassia N, Wei P, Nardelli B, Roschke V, Vecchi A, Mantovani A, Bambara LM, Edwards SW, Carletto A. Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis.
J. Immunol. 178: 7325-7333 (2007).
*
-
Cassiani-Ingoni R, Cabral ES, Lunemann JD, Garza Z, Magnus T, Gelderblom H, Munson PJ, Marques A, Martin R. Borrelia burgdorferi induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expression.
J. Neuropathol. Exp. Neurol. 65: 540-548 (2006).
-
Castagnini C, Luceri C, Toti S, Bigagli E, Caderni G, Femia AP, Giovannelli L, Lodovici M, Pitozzi V, Salvadori M, Messerini L, Martin R, Zoetendal EG, Gaj S, Eijssen L, Evelo CT, Renard CM, Baron A, Dolara P. Reduction of colonic inflammation in HLA-B27 transgenic rats by feeding Marie Menard apples, rich in polyphenols.
Br. J. Nutr. 102: 1620-1628 (2009).
*
-
Castaldo G, Fuccio A, Salvatore D, Raia V, Santostasi T, Leonardi S, Lizzi N, La Rosa M, Rigillo N, Salvatore F. Liver expression in cystic fibrosis could be modulated by genetic factors different from the cystic fibrosis transmembrane regulator genotype.
Am. J. Med. Genet. 98: 294-297 (2001).
*
-
Castaldo G, Rippa E, Salvatore D, Sibillo R, Raia V, de Ritis G, Salvatore F. Severe liver impairment in a cystic fibrosis-affected child homozygous for the G542X mutation.
Am. J. Med. Genet. 69: 155-158 (1997).
-
Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, Kolachala VL, Rojas M, Wang L, Oprea G, Garg P, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.
Gastroenterology 129: 1991-2008 (2005).
*
-
Castellaneta A, Di Leo A, Francavilla R, Margiotta M, Barone M, Amoruso A, Troiani L, Thomson AW, Francavilla A. Functional modification of CD11c(+) liver dendritic cells during liver regeneration after partial hepatectomy in mice.
Hepatology 43: 807-816 (2006).
*
-
Castellanos-Rubio A, Martin-Pagola A, Santin I, Hualde I, Aransay AM, Castano L, Vitoria JC, Bilbao JR. Combined functional and positional gene information for the identification of susceptibility variants in celiac disease.
Gastroenterology 134: 738-746 (2008).
*
-
Castellanos-Rubio A, Santin I, Irastorza I, Castano L, Carlos Vitoria J, Ramon Bilbao J. TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin.
Autoimmunity 42: 69-73 (2009).
-
Castellanos-Rubio A, Santin I, Martin-Pagola A, Irastorza I, Castano L, Vitoria JC, Bilbao JR. Long-term and acute effects of gliadin on small intestine of patients on potentially pathogenic networks in celiac disease.
Autoimmunity Oct 9 [Epub ahead of print] (2009).
-
Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE. Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis.
Scand. J. Immunol. 69: 479-491 (2009).
*
-
Castelli EC, Mendes-Junior CT, Deghaide NH, de Albuquerque RS, Muniz YC, Simoes RT, Carosella ED, Moreau P, Donadi EA. The genetic structure of 3'untranslated region of the HLA-G gene: polymorphisms and haplotypes.
Genes Immun. Oct 1 [Epub ahead of print] (2009).
*
-
Castelli R, Ferrari B, Cortelezzi A, Guariglia A. Thromboembolic complications in malignant haematological disorders.
Curr. Vasc. Pharmacol. Jan 1 [Epub ahead of print] (2010).
-
Castellino FJ, Ploplis VA. The protein C pathway and pathologic processes.
J. Thromb. Haemost. 7 Suppl. 1: 140-145 (2009).
-
Castermans D, Vermeesch JR, Fryns JP, Steyaert JG, Van de Ven WJ, Creemers JW, Devriendt K. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism.
Eur. J. Hum. Genet. 15: 422-431 (2007).
*
-
Castiglione F, Taddei A, Degl'Innocenti DR, Buccoliero AM, Bechi P, Garbini F, Chiara FG, Moncini D, Cavallina G, Marascio L, Freschi G, Gian LT. Expression of estrogen receptor beta in colon cancer progression.
Diagn. Mol. Pathol. 17: 231-236 (2008).
-
Castillero E, Martin AI, Lopez-Menduina M, Villanua MA, Lopez-Calderon A. Eicosapentaenoic acid attenuates arthritis-induced muscle wasting acting on atrogin-1 and on myogenic regulatory factors.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 297: R1322-R1331 (2009).
*
-
Castillo AI, Sanchez-Martinez R, Moreno JL, Martinez-Iglesias OA, Palacios D, Aranda A. A permissive retinoid X receptor/thyroid hormone receptor heterodimer allows stimulation of prolactin gene transcription by thyroid hormone and 9-cis-retinoic acid.
Mol. Cell. Biol. 24: 502-513 (2004).
*
-
Castillo J, Goni S, Latasa MU, Perugorría MJ, Calvo A, Muntane J, Bioulac-Sage P, Balabaud C, Prieto J, Avila MA, Berasain C. Amphiregulin induces the alternative splicing of p73 into its oncogenic isoform DeltaEx2p73 in human hepatocellular tumours.
Gastroenterology 137: 1805-1815.e4 (2009).
*
-
Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages.
J. Biol. Chem. 278: 10443-10449 (2003).
*
-
Castriota G, Thompson GM, Lin Y, Scherer PE, Moller DE, Berger JP. Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein.
Cell Biol. Int. 31: 586-591 (2007).
*
-
Castro J, Amigo L, Miquel JF, Galman C, Crovari F, Raddatz A, Zanlungo S, Jalil R, Rudling M, Nervi F. Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease.
Hepatology 45: 1261-1266 (2007).
*
-
Castro J, Balada E, Ordi-Ros J, Vilardell-Tarres M. The complex immunogenetic basis of systemic lupus erythematosus.
Autoimmun. Rev. 7: 345-351 (2008).
-
Castro RE, Sola S, Ma X, Ramalho RM, Kren BT, Steer CJ, Rodrigues CM. A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid.
J. Hepatol. 42: 897-906 (2005).
*
-
Castro-Chavez F. Microarrays, antiobesity and the liver.
Ann. Hepatol. 3: 137-145 (2004).
*
-
Castro-Parodi M, Levi L, Dietrich V, Zotta E, Damiano AE. CFTR may modulate AQP9 functionality in preeclamptic placentas.
Placenta 30: 642-648 (2009).
-
Catalano M, Cortelazzo A, Santi R, Contino L, Demicheli M, Yilmaz Y, Zorzetto M, Campo I, Lanati N, Emanuele E. The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease.
Clin. Biochem. 41: 981-985 (2008).
*
-
Cataldegirmen G, Zeng S, Feirt N, Ippagunta N, Dun H, Qu W, Lu Y, Rong LL, Hofmann MA, Kislinger T, Pachydaki SI, Jenkins DG, Weinberg A, Lefkowitch J, Rogiers X, Yan SF, Schmidt AM, Emond JC. RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB.
J. Exp. Med. 201: 473-484 (2005).
*
-
Cataldo F, Lio D, Marino V, Scola L, Crivello A, Mule AM, Corazza GR; Groups of the SIGEP and "Club del Tenue". Cytokine genotyping (TNF and IL-10) in patients with celiac disease and selective IgA deficiency.
Am. J. Gastroenterol. 98: 850-856 (2003).
*
-
Caterino M, Ruoppolo M, Fulcoli G, Huynth T, Orru S, Baldini A, Salvatore F. Transcription factor TBX1 overexpression induces downregulation of proteins involved in retinoic acid metabolism: a comparative proteomic analysis.
J. Proteome Res. 8: 1515-1526 (2009).
*
-
Cato AC, Schacke H, Sterry W, Asadullah K. The glucocorticoid receptor as target for classic and novel anti-inflammatory therapy.
Curr. Drug Targets Inflamm. Allergy 3: 347-353 (2004).
-
Cattin AL, Le Beyec J, Barreau F, Saint-Just S, Houllier A, Gonzalez FJ, Robine S, Pincon-Raymond M, Cardot P, Lacasa M, Ribeiro A. Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.
Mol. Cell. Biol. 29: 6294-6308 (2009).
*
-
Caudy AA, Reddy ST, Chatila T, Atkinson JP, Verbsky JW. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome and defective IL-10 expression from CD4 lymphocytes.
J. Allergy Clin. Immunol. 119: 482-487 (2007).
*
-
Cauli A, Dessole G, Fiorillo MT, Vacca A, Mameli A, Bitti P, Passiu G, Sorrentino R, Mathieu A. Increased level of HLA-B27 expression in ankylosing spondylitis patients compared with healthy HLA-B27-positive subjects: a possible further susceptibility factor for the development of disease.
Rheumatology (Oxford) 41: 1375-1379 (2002).
*
-
Cavadini G, Petrzilka S, Kohler P, Jud C, Tobler I, Birchler T, Fontana A. TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription.
Proc. Natl. Acad. Sci. U.S.A. 104: 12843-12848 (2007).
*
-
Cavadini P, Vermi W, Facchetti F, Fontana S, Nagafuchi S, Mazzolari E, Sediva A, Marrella V, Villa A, Fischer A, Notarangelo LD, Badolato R. AIRE deficiency in thymus of 2 patients with Omenn syndrome.
J. Clin. Invest. 115: 728-732 (2005).
*
-
Cavalieri D, Calura E, Romualdi C, Marchi E, Radonjic M, van Ommen B, Muller M. Filling gaps in PPAR-alpha signaling through comparative nutrigenomics analysis.
BMC Genomics 10: 596 (2009).
*
-
Cavallaro S, Paratore S, Fradale F, de Vrij FM, Willemsen R, Oostra BA. Genes and pathways differentially expressed in the brains of Fxr2 knockout mice.
Neurobiol. Dis. 32: 510-520 (2008).
-
Cave WT Jr. Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis.
FASEB J. 5: 2160-2166 (1991).
*
-
Cavelier LB, Qiu Y, Bielicki JK, Afzal V, Cheng JF, Rubin EM. Regulation and activity of the human ABCA1 gene in transgenic mice.
J. Biol. Chem. 276: 18046-18051 (2001).
*
-
Cawkwell L, Sutherland F, Murgatroyd H, Jarvis P, Gray S, Cross D, Shepherd N, Day D, Quirke P. Defective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers.
Gut 46: 367-369 (2000).
*
-
Cawood AL, Carroll MP, Wootton SA, Calder PC. Is there a case for n-3 fatty acid supplementation in cystic fibrosis?
Curr. Opin. Clin. Nutr. Metab. Care 8: 153-159 (2005).
-
Cawthorn TR, Amir E, Broom R, Freedman O, Gianfelice D, Barth D, Wang D, Holen I, Done SJ, Clemons M. Mechanisms and pathways of bone metastasis: challenges and pitfalls of performing molecular research on patient samples.
Clin. Exp. Metastasis 26: 935-943 (2009).
-
Cawthorn WP, Heyd F, Hegyi K, Sethi JK. Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway.
Cell Death Differ. 14: 1361-1373 (2007).
*
-
Cayla C, Schaak S, Crassous PA, Buffin-Meyer B, Delage C, Paris H, Senard JM, Denis C. Transcriptional down-regulation of human alpha(2A)-adrenoceptors by IFNgamma and TNFalpha in intestinal cells.
Eur. J. Pharmacol. 588: 33-40 (2008).
*
-
Cayon A, Crespo J, Guerra AR, Pons-Romero F. Gene expression in obese patients with non-alcoholic steatohepatitis.
Rev. Esp. Enferm. Dig. 100: 212-218 (2008).
-
Cebecauerova D, Jirasek T, Budisova L, Mandys V, Volf V, Novotna Z, Subhanova I, Hrebicek M, Elleder M, Jirsa M. Dual hereditary jaundice: simultaneous occurrence of mutations causing Gilbert's and Dubin-Johnson syndrome.
Gastroenterology 129: 315-320 (2005).
*
-
Cebotaru L, Vij N, Ciobanu I, Wright J, Flotte T, Guggino WB. Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and uF508 processing.
J. Biol. Chem. 283: 21926-21933 (2008).
*
-
Cecere A, Caiazzo R, Romano C, Gattoni A. Primary biliary cirrhosis.
Clin. Ter. 149: 143-150 (1998).
-
Cecil DL, Johnson K, Rediske J, Lotz M, Schmidt AM, Terkeltaub R. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products.
J. Immunol. 175: 8296-8302 (2005).
*
-
Ceelie H, Spaargaren-Van Riel CC, De Jong M, Bertina RM, Vos HL. Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer.
J. Thromb. Haemost. 1: 1688-1698 (2003).
*
-
Cejkova J, Ardan T, Jirsova K, Jechova G, Malec J, Simonova Z, Cejka C, Filipec M, Dotrelova D, Brunova B. The role of conjunctival epithelial cell xanthine oxidoreductase/xanthine oxidase in oxidative reactions on the ocular surface of dry eye patients with Sjogren's syndrome.
Histol. Histopathol. 22: 997-1003 (2007).
-
Cejkova J, Ardan T, Simonova Z, Cejka C, Malec J, Dotrelova D, Brunova B. Decreased expression of antioxidant enzymes in the conjunctival epithelium of dry eye (Sjogren's syndrome) and its possible contribution to the development of ocular surface oxidative injuries.
Histol. Histopathol. 23: 1477-1483 (2008).
*
-
Celinska-Lowenhoff M, Undas A. Nonlipid effects of fibrates.
Przegl. Lek. 61: 99-101 (2004).
-
Celius T, Garberg P, Lundgren B. Stable suppression of MDR1 gene expression and function by RNAi in Caco-2 cells.
Biochem. Biophys. Res. Commun. 324: 365-371 (2004).
*
-
Ceni E, Crabb DW, Foschi M, Mello T, Tarocchi M, Patussi V, Moraldi L, Moretti R, Milani S, Surrenti C, Galli A. Acetaldehyde inhibits PPARgamma via H(2)O(2)-mediated c-Abl activation in human hepatic stellate cells.
Gastroenterology 131: 1235-1252 (2006).
*
-
Centola M, Frank MB, Bolstad AI, Alex P, Szanto A, Zeher M, Hjelmervik TO, Jonsson R, Nakken B, Szegedi G, Szodoray P. Genome-scale assessment of molecular pathology in systemic autoimmune diseases using microarray technology: a potential breakthrough diagnostic and individualized therapy-design tool.
Scand. J. Immunol. 64: 236-242 (2006).
*
-
Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D'Amelio M, Cavallucci V, Martorana A, Bergamaschi A, Cencioni MT, Diamantini A, Butti E, Comi G, Bernardi G, Cecconi F, Battistini L, Furlan R, Martino G. Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis.
J. Neurosci. 29: 3442-3452 (2009).
-
Centonze D, Muzio L, Rossi S, Furlan R, Bernardi G, Martino G. The link between inflammation, synaptic transmission and neurodegeneration in multiple sclerosis.
Cell Death Differ. Nov 20 [Epub ahead of print] (2009).
*
-
Centrella M, Christakos S, McCarthy TL. Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression.
Gene 342: 13-24 (2004).
*
-
Ceperuelo-Mallafre V, Miranda M, Chacon MR, Vilarrasa N, Megia A, Gutierrez C, Fernandez-Real JM, Gomez JM, Caubet E, Fruhbeck G, Vendrell J. Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in severe obesity but not in type 2 diabetes.
J. Clin. Endocrinol. Metab. 92: 3640-3645 (2007).
*
-
Cepok S, Zhou D, Srivastava R, Nessler S, Stei S, Bussow K, Sommer N, Hemmer B. Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis.
J. Clin. Invest. 115: 1352-1360 (2005).
*
-
Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation.
FASEB J. 10: 267-282 (1996).
*
-
Cerman AA, Bozkurt S, Sav A, Tulunay A, Elbasi MO, Ergun T. Serum leptin levels, skin leptin and leptin receptor expression in psoriasis.
Br. J. Dermatol. 159: 820-826 (2008).
*
-
Cerruti F, Martano M, Petterino C, Bollo E, Morello E, Bruno R, Buracco P, Cascio P. Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer.
Neoplasia 9: 960-969 (2007).
*
-
Cerutti E, Campagnoli MF, Ferretti M, Garelli E, Crescenzio N, Rosolen A, Chiocchetti A, Lenardo MJ, Ramenghi U, Dianzani U. Co-inherited mutations of Fas and caspase-10 in development of the autoimmune lymphoproliferative syndrome.
BMC Immunol. 8: 28 (2007).
*
-
Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P. Valproic acid induces CYP3A4 and MDR1 genes expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Drug Metab. Dispos. 35: 1032-1041 (2007).
*
-
Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.
Immunity 12: 721-727 (2000).
*
-
Cesaratto L, Vascotto C, Calligaris S, Tell G. The importance of redox state in liver damage.
Ann. Hepatol. 3: 86-92 (2004).
*
-
Cetindere T, Nambiar S, Santourlidis S, Essmann F, Hassan M. Induction of indoleamine 2, 3-dioxygenase by death receptor activation contributes to apoptosis of melanoma cells via mitochondrial damage-dependent ROS accumulation.
Cell. Signal. 22: 197-211 (2010).
*
-
Cetinkaya C, Hultquist A, Su Y, Wu S, Bahram F, Påhlman S, Guzhova I, Larsson LG. Combined IFN-gamma and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells.
Mol. Cancer Ther. 6: 2634-2641 (2007).
-
Cha B, Kim KH, Kim H. 15-Deoxy-delta 12, 14,-prostaglandin J2 suppresses nuclear factor-kappaB-mediated apoptosis of Helicobacter pylori-infected gastric epithelial cells.
Ann. N. Y. Acad. Sci. 1171: 457-463 (2009).
*
-
Cha DR, Zhang X, Zhang Y, Wu J, Su DM, Han JY, Fang X, Yu B, Breyer MD, Guan Y. Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice.
Diabetes 56: 2036-2045 (2007).
*
-
Cha EJ, Oh BC, Wee HJ, Chi XZ, Goh YM, Lee KS, Ito Y, Bae SC. E1A physically interacts with RUNX3 and inhibits its transactivation activity.
J. Cell. Biochem. 105: 236-244 (2008).
*
-
Cha JY, Kim H, Kim KS, Hur MW, Ahn Y. Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1alpha and 3beta.
J. Biol. Chem. 275: 18358-18365 (2000).
*
-
Cha JY, Repa JJ. The liver X receptor and hepatic lipogenesis: the carbohydrate-response element binding protein is a target gene of LXR.
J. Biol. Chem. 282: 743-751 (2007).
*
-
Cha S, Brayer J, Gao J, Brown V, Killedar S, Yasunari U, Peck AB. A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse.
Scand. J. Immunol. 60: 552-565 (2004).
*
-
Cha Y, Sung MK, Jung KW, Kim HH, Lee SM, Park KS. Epigenetic deregulation of the human Oct4 promoter in mouse cells.
Dev. Genes Evol. 218: 561-566 (2008).
*
-
Chabane N, Zayed N, Afif H, Mfuna-Endam L, Benderdour M, Boileau C, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E(2) production in human chondrocytes.
Osteoarthritis Cartilage 16: 1267-1274 (2008).
-
Chabas D. Osteopontin, a multi-faceted molecule.
Med. Sci. (Paris) 21: 832-838 (2005).
-
Chabas D, Green AJ, Waubant E. Pediatric multiple sclerosis.
NeuroRx. 3: 264-275 (2006).
-
Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith JC Jr, Albert LM, Leathurby Y, Harris HA, Bhat RA, Ashwell M, Trybulski E, Winneker RC, Adelman SJ, Steffan RJ, Harnish DC. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity.
Proc. Natl. Acad. Sci. U.S.A. 102: 2543-2548 (2005).
*
-
Chae BS, Shin TY. Immunoregulatory abnormalities of T cells and hyperreactivity of B cells in the in vitro immune response in pristane-induced lupus mice.
Arch. Pharm. Res. 30: 191-198 (2007).
-
Chae S, Jun HO, Lee EG, Yang SJ, Lee DC, Jung JK, Park KC, Yeom YI, Kim KW. Osteopontin splice variants differentially modulate the migratory activity of hepatocellular carcinoma cell lines.
Int. J. Oncol. 35: 1409-1416 (2009).
-
Chae SC, Park BL, Park CS, Ryu HJ, Yang YS, Lee SO, Choi YH, Kim EM, Uh ST, Kim YH, Kim KK, Oh B, Chung HT, Kimm K, Shin HD. Putative association of RUNX1 polymorphisms with IgE levels in a Korean population.
Exp. Mol. Med. 38: 583-588 (2006).
*
-
Chae SC, Yu JI, Oh GJ, Choi CS, Choi SC, Yang YS, Yun KJ. Identification of single nucleotide polymorphisms in the TNFRSF17 gene and their association with gastrointestinal disorders.
Mol. Cells Dec 7 [Epub ahead of print] (2009).
*
-
Chakraborty G, Jain S, Behera R, Ahmed M, Sharma P, Kumar V, Kundu GC. The multifaceted roles of osteopontin in cell signaling, tumor progression and angiogenesis.
Curr. Mol. Med. 6: 819-830 (2006).
-
Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T, Turk J, Semenkovich CF. "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis.
Cell. Metab. 1: 309-322 (2005).
*
-
Chakravarti N, Lotan R, Diwan AH, Warneke CL, Johnson MM, Prieto VG. Decreased expression of retinoid receptors in melanoma: entailment in tumorigenesis and prognosis.
Clin. Cancer Res. 13: 4817-4824 (2007).
*
-
Chakravarty SD, Zhu G, Tsai MC, Mohan VP, Marina S, Kirschner DE, Huang L, Flynn J, Chan J. Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs.
Infect. Immun. 76: 916-926 (2008).
*
-
Chakraverty R, Flutter B, Fallah-Arani F, Eom HS, Means T, Andreola G, Schwarte S, Buchli J, Cotter P, Zhao G, Sykes M. The host environment regulates the function of CD8+ graft-versus-host-reactive effector cells.
J. Immunol. 181: 6820-6828 (2008).
*
-
Chalasani N, Gorski JC, Asghar MS, Asghar A, Foresman B, Hall SD, Crabb DW. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis.
Hepatology 37: 544-550 (2003).
*
-
Challet E. Clock genes, circadian rhythms and food intake.
Pathol. Biol. (Paris) 55: 176-177 (2007).
-
Chaluvadi MR, Nyagode BA, Kinloch RD, Morgan ET. TLR4-dependent and -independent regulation of hepatic cytochrome P450 in mice with chemically induced inflammatory bowel disease.
Biochem. Pharmacol. 77: 464-471 (2009).
*
-
Chambon P. The retinoid signaling pathway: molecular and genetic analyses.
Semin. Cell Biol. 5: 115-125 (1994).
-
Chambon P. A decade of molecular biology of retinoic acid receptors.
FASEB J. 10: 940-954 (1996).
*
-
Chambrier C, Bastard JP, Rieusset J, Chevillotte E, Bonnefont-Rousselot D, Therond P, Hainque B, Riou JP, Laville M, Vidal H. Eicosapentaenoic acid induces mRNA expression of peroxisome proliferator-activated receptor gamma.
Obes. Res. 10: 518-525 (2002).
*
-
Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris.
Proc. Natl. Acad. Sci. U.S.A. 102: 2075-2080 (2005).
*
-
Chamorro CI, Weber G, Gronberg A, Pivarcsi A, Stahle M. The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes.
J. Invest. Dermatol. 129: 937-944 (2009).
*
-
Chan AO, Rashid A. CpG island methylation in precursors of gastrointestinal malignancies.
Curr. Mol. Med. 6: 401-408 (2006).
-
Chan AS, Jensen KK, Skokos D, Doty S, Lederman HK, Kaplan RN, Rafii S, Rivella S, Lyden D. Id1 represses osteoclast-dependent transcription and affects bone formation and hematopoiesis.
PLoS One 4: e7955 (2009).
*
-
Chan BY, Gartland A, Wilson PJ, Buckley KA, Dillon JP, Fraser WD, Gallagher JA. PPAR agonists modulate human osteoclast formation and activity in vitro.
Bone 40: 149-159 (2007).
*
-
Chan J, Clements W, Field J, Nasa Z, Lock P, Yap F, Toh BH, Alderuccio F. Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice.
J. Gene Med. 8: 1281-1290 (2006).
-
Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis.
J. Exp. Med. 203: 2577-2587 (2006).
*
-
Chan JY, Li L, Miao J, Cai DQ, Lee KK, Chui YL. Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.
Mol. Biol. Rep. Sep 16 [Epub ahead of print] (2009).
*
-
Chan LY, Leung JC, Tsang AW, Tang SC, Lai KN. Activation of tubular epithelial cells by mesangial-derived TNF-alpha: glomerulotubular communication in IgA nephropathy.
Kidney Int. 67: 602-612 (2005).
*
-
Chan MM, Chmura K, Chan ED. Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene.
Cytokine 33: 309-316 (2006).
-
Chan RW, Lai FM, Li EK, Tam LS, Chow KM, Lai KB, Li PK, Szeto CC. Intra-renal cytokine gene expression in lupus nephritis.
Ann. Rheum. Dis. 66: 886-892 (2007).
*
-
Chan SH, Wu CA, Wu KL, Ho YH, Chang AY, Chan JY. Transcriptional upregulation of mitochondrial uncoupling protein 2 protects against oxidative stress-associated neurogenic hypertension.
Circ. Res. 105: 886-896 (2009).
-
Chan SS, Schedlich LJ, Twigg SM, Baxter RC. Inhibition of adipocyte differentiation by insulin-like growth factor binding protein-3.
Am. J. Physiol. Endocrinol. Metab. 296: E654-E663 (2009).
*
-
Chan YC, Leung PS. Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis.
J. Pharmacol. Exp. Ther. 323: 10-18 (2007).
*
-
Chan YH, Chiang MF, Tsai YC, Su ST, Chen MH, Hou MS, Lin KI. Absence of the transcriptional repressor Blimp-1 in hematopoietic lineages reveals its role in dendritic cell homeostatic development and function.
J. Immunol. 183: 7039-7046 (2009).
-
Chance SA. Subtle changes in the ageing human brain.
Nutr. Health 18: 217-224 (2006).
-
Chanda D, Lee CH, Kim YH, Noh JR, Kim DK, Park JH, Hwang JH, Lee MR, Jeong KH, Lee IK, Kweon GR, Shong M, Oh GT, Chiang JY, Choi HS. Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner.
Hepatology 50: 880-892 (2009).
-
Chanda D, Li T, Song KH, Kim YH, Sim J, Lee CH, Chiang JY, Choi HS. Hepatocyte growth factor family negatively regulates hepatic gluconeogenesis via induction of orphan nuclear receptor small heterodimer partner in primary hepatocytes.
J. Biol. Chem. 284: 28510-28521 (2009).
*
-
Chandalia A, Clarke HJ, Clemens LE, Pandey B, Vicena V, Lee P, Lavan BE, Gregoire FM. MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-gamma agonist lowers triglyceride independently of PPAR-alpha activation.
PPAR Res. 2009: 706852 (2009).
*
-
Chandra AP, Ouyang L, Yi S, Wong JK, Ha H, Walters SN, Patel AT, Stokes R, Jardine M, Hawthorne WJ, O'Connell PJ. Chemokine and Toll-like receptor signaling in macrophage mediated islet xenograft rejection.
Xenotransplantation 14: 48-59 (2007).
*
-
Chandra P, Brouwer KL. The complexities of hepatic drug transport: current knowledge and emerging concepts.
Pharm. Res. 21: 719-735 (2004).
*
-
Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA.
Nature 456: 350-356 (2008).
*
-
Chandrasekharan B, Bala V, Kolachala VL, Vijay-Kumar M, Jones D, Gewirtz AT, Sitaraman SV, Srinivasan S. Targeted deletion of neuropeptide Y (NPY) modulates experimental colitis.
PLoS ONE 3: e3304 (2008).
*
-
Chang AJ, Song DH, Wolfe MM. Attenuation of peroxisome proliferator activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation.
J. Biol. Chem. 281: 14700-14710 (2006).
*
-
Chang BE, Blader P, Fischer N, Ingham PW, Strahle U. Axial (HNF3beta) and retinoic acid receptors are regulators of the zebrafish sonic hedgehog promoter.
EMBO J. 16: 3955-3964 (1997).
*
-
Chang CC, Chen SC, Hsieh YH, Chen YC, Chen TY, Chu YH, Ma HJ, Chou MC, Tsai HT, Yang SF. Stromal cell-derived factor-1 but not its receptor, CXCR4, gene variants increase susceptibility and pathological development of hepatocellular carcinoma.
Clin. Chem. Lab. Med. 47: 412-418 (2009).
*
-
Chang CC, Silvia EA, Ho EK, Vlad G, Suciu-Foca N, Vasilescu ER. Polymorphism and linkage disequilibrium of immunoglobulin-like transcript 3 gene.
Hum. Immunol. 69: 284-290 (2008).
-
Chang CC, Wang SS, Huang HC, Lee FY, Lin HC, Lee JY, Chen YC, Lee SD. Chronic thalidomide administration enhances vascular responsiveness to vasopressin in portal-systemic collaterals of bile duct-ligated rats.
J. Chin. Med. Assoc. 72: 234-242 (2009).
-
Chang CH, Flavell RA. Class II transactivator regulates the expression of multiple genes involved in antigen presentation.
J. Exp. Med. 181: 765-767 (1995).
*
-
Chang CL, Hong E, Lao-Sirieix P, Fitzgerald RC. A novel role for the retinoic acid-catabolizing enzyme CYP26A1 in Barrett's associated adenocarcinoma.
Oncogene 27: 2951-260 (2008).
*
-
Chang H, Hanawa H, Liu H, Yoshida T, Hayashi M, Watanabe R, Abe S, Toba K, Yoshida K, Elnaggar R, Minagawa S, Okura Y, Kato K, Kodama M, Maruyama H, Miyazaki J, Aizawa Y. Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats.
J. Immunol. 177: 3635-3643 (2006).
*
-
Chang H, Hanawa H, Yoshida T, Hayashi M, Liu H, Ding L, Otaki K, Hao K, Yoshida K, Kato K, Toba K, Kodama M, Maruyama H, Miyazaki J, Aizawa Y. Alteration of IL-17 related protein expressions in experimental autoimmune myocarditis and inhibition of IL-17 by IL-10-Ig fusion gene transfer.
Circ. J. 72: 813-819 (2008).
*
-
Chang HC, Han L, Jabeen R, Carotta S, Nutt SL, Kaplan MH. PU.1 regulates TCR expression by modulating GATA-3 activity.
J. Immunol. 183: 4887-4894 (2009).
-
Chang HD, Radbruch A. The pro- and anti-inflammatory potential of interleukin-12.
Ann. N. Y. Acad. Sci. 1109: 40-46 (2007).
*
-
Chang HS, Kim JS, Lee JH, Cho JI, Rhim TY, Uh ST, Park BL, Chung IY, Park CS, Shin HD. A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes.
J. Immunol. 174: 1525-1531 (2005).
*
-
Chang JH, Lin KH, Shih CH, Chang YJ, Chi HC, Chen SL. Myogenic basic helix-loop-helix proteins regulate the expression of peroxisomal proliferator activated receptor-gamma coactivator-1alpha.
Endocrinology 147: 3093-3106 (2006).
*
-
Chang JH, McCluskey PJ, Wakefield D. Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease.
Br. J. Ophthalmol. 90: 103-108 (2006).
-
Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins S, Wang W, Wang Y, Lacava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S. Liver X receptor is a therapeutic target for photoaging and chronological skin aging.
Mol. Endocrinol. 22: 2407-2419 (2008).
*
-
Chang LT, Sun CK, Wang CY, Youssef AA, Wu CJ, Chua S, Yip HK. Downregulation of peroxisme proliferator activated receptor gamma co-activator 1alpha in diabetic rats.
Int. Heart J. 47: 901-910 (2006).
-
Chang MH, Dipiero J, Sonnichsen FD, Romero MF. Entry to "HCO3 tunnel" revealed by SLC4A4 human mutation and structural model.
J. Biol. Chem. 283: 18402-18410 (2008).
*
-
Chang ML, Yeh CT, Lin DY, Ho YP, Hsu CM, Bissell DM. Hepatic inflammation mediated by hepatitis C virus core protein is ameliorated by blocking complement activation.
BMC Med. Genomics 2: 51 (2009).
*
-
Chang Q, Zhang Y, Beezhold KJ, Bhatia D, Zhao H, Chen J, Castranova V, Shi X, Chen F. Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer.
J. Hepatol. 50: 323-333 (2009).
-
Chang TK, Bandiera SM, Chen J. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels.
Drug Metab. Dispos. 31: 7-10 (2003).
*
-
Chang TL, Ito K, Ko TK, Liu Q, Salto-Tellez M, Yeoh KG, Fukamachi H, Ito Y. Claudin-1 has tumor suppressive activity and is a direct target of RUNX3 in gastric epithelial cells.
Gastroenterology 138: 255-265.e3 (2010).
*
-
Chang TT, Hughes-Fulford M. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes.
Tissue Eng. Part A. 15: 559-567 (2009).
-
Chang WW, Su IJ, Lai MD, Chang WT, Huang W, Lei HY. Toll-like receptor 4 plays an anti-HBV role in a murine model of acute hepatitis B virus expression.
World J. Gastroenterol. 11: 6631-6637 (2005).
*
-
Chang X, Gao JX, Jiang Q, Wen J, Seifers N, Su L, Godfrey VL, Zuo T, Zheng P, Liu Y. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis.
J. Exp. Med. 202: 1141-1151 (2005).
*
-
Chang X, Yamada R, Sawada T, Suzuki A, Kochi Y, Yamamoto K. The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritis.
Rheumatology (Oxford) 44: 293-298 (2005).
*
-
Chang X, Yamada R, Suzuki A, Kochi Y, Sawada T, Yamamoto K. Citrullination of fibronectin in rheumatoid arthritis synovial tissue.
Rheumatology (Oxford) 44: 1374-1382 (2005).
*
-
Chang X, Yamada R, Suzuki A, Sawada T, Yoshino S, Tokuhiro S, Yamamoto K. Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis.
Rheumatology (Oxford) 44: 40-50 (2005).
*
-
Chang X, Zheng P, Liu Y. Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity.
J. Immunol. 181: 2399-2406 (2008).
*
-
Chang XH, Zhang L, Yang R, Feng J, Cheng YX, Cheng HY, Ye X, Fu TY, Cui H. Screening for genes associated with ovarian cancer prognosis.
Chin. Med. J. (Engl.) 122: 1167-1172 (2009).
-
Chang Y, Jiang HJ, Sun XM, Cai XK, He XX, Li PY, Tang WX, Song YH, Lin JS. Hepatic stellate cell-specific gene silencing induced by an artificial microRNA for antifibrosis in vitro.
Dig. Dis. Sci. Nov 5 [Epub ahead of print] (2009).
*
-
Chang Y, Yap S, Ge X, Piganelli J, Bertera S, Giannokakis N, Mathews C, Prud'homme G, Trucco M. DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice.
Gene Ther. 12: 1679-1685 (2005).
*
-
Chang YC, Chen TC, Lee CT, Yang CY, Wang HW, Wang CC, Hsieh SL. Epigenetic control of MHC-II expression in tumor-associated macrophages by decoy receptor 3.
Blood 111: 5054-5063 (2008).
*
-
Chang YC, Kao YH, Hu DN, Tsai LY, Wu WC. All-trans retinoic acid remodels extracellular matrix and suppresses laminin-enhanced contractility of cultured human retinal pigment epithelial cells.
Exp. Eye Res. 88: 900-909 (2009).
-
Chang YT, Hsu C, Jeng YM, Chang MC, Wei SC, Wong JM. Expression of the caudal-type homeodomain transcription factor CDX2 is related to clinical outcome in biliary tract carcinoma.
J. Gastroenterol. Hepatol. 22: 389-394 (2007).
*
-
Changhui M, Tianzhong M, Zhongjing S, Ling C, Ning W, Ningxia Z, Xiancai C, Haibin C. Silencing of tumor necrosis factor receptor 1 by siRNA in EC109 cells affects cell proliferation and apoptosis.
J. Biomed. Biotechnol. 2009: 760540 (2009).
*
-
Chanson M, Berclaz PY, Scerri I, Dudez T, Wernke-Dollries K, Pizurki L, Pavirani A, Fiedler MA, Suter S. Regulation of gap junctional communication by a pro-inflammatory cytokine in cystic fibrosis transmembrane conductance regulator-expressing but not cystic fibrosis airway cells.
Am. J. Pathol. 158: 1775-1784 (2001).
*
-
Chanson M, Scerri I, Suter S. Defective regulation of gap junctional coupling in cystic fibrosis pancreatic duct cells.
J. Clin. Invest. 103: 1677-1684 (1999).
*
-
Chao C, Hellmich MR. Gastrin, inflammation, and carcinogenesis.
Curr. Opin. Endocrinol. Diabetes Obes. 17: 33-39 (2010).
-
Chao C, Youssef J, Rezaiekhaleigh M, Birnbaum LS, Badr M. Senescence-associated decline in hepatic peroxisomal enzyme activities corresponds with diminished levels of retinoid X receptor alpha, but not peroxisome proliferator-activated receptor alpha.
Mech. Ageing Dev. 123: 1469-1476 (2002).
-
Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity.
J. Med. Chem. 51: 5758-5765 (2008).
*
-
Chao HH, Liu JC, Hong HJ, Lin JW, Chen CH, Cheng TH. L-Carnitine reduces doxorubicin-induced apoptosis through a prostacyclin-mediated pathway in neonatal rat cardiomyocytes.
Int. J. Cardiol. Jun 22 [Epub ahead of print] (2009).
-
Chao YC, Chang SF, Lu SC, Hwang TC, Hsieh WH, Liaw J. Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation.
J. Control Release 118: 105-117 (2007).
-
Chaparro M, Sanz-Cameno P, Trapero-Marugan M, Garcia-Buey L, Moreno-Otero R. Mechanisms of angiogenesis in chronic inflammatory liver disease.
Ann. Hepatol. 6: 208-213 (2007).
*
-
Chapkin RS, Seo J, McMurray DN, Lupton JR. Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine.
Chem. Phys. Lipids 153: 14-23 (2008).
*
-
Chapman C, Morgan LM, Murphy MC. Maternal and early dietary fatty acid intake: changes in lipid metabolism and liver enzymes in adult rats.
J. Nutr. 130: 146-151 (2000).
*
-
Chapman RW. The management of primary sclerosing cholangitis.
Curr. Gastroenterol. Rep. 5: 9-17 (2003).
-
Chapman RW, Kelly PM, Heryet A, Jewell DP, Fleming KA. Expression of HLA-DR antigens on bile duct epithelium in primary sclerosing cholangitis.
Gut 29: 422-427 (1988).
*
-
Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, Dekosky ST, Lemoine Y, Iwatsubo T, Wavrant-Devrieze F, Dartigues JF, Tzourio C, Buee L, Pasquier F, Berr C, et al. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.
Mol. Psychiatry 14: 1004-1016 (2009).
-
Charles KA, Kulbe H, Soper R, Escorcio-Correia M, Lawrence T, Schultheis A, Chakravarty P, Thompson RG, Kollias G, Smyth JF, Balkwill FR, Hagemann T. The tumor-promoting actions of TNF-alpha involve TNFR1 and IL-17 in ovarian cancer in mice and humans.
J. Clin. Invest. 119: 3011-3023 (2009).
*
-
Charng MJ, Wu CH. Transcriptional activation of p21 by Tranilast is mediated via transforming growth factor beta signal pathway.
Br. J. Pharmacol. 147: 117-124 (2006).
*
-
Charoenphandhu N, Teerapornpuntakit J, Methawasin M, Wongdee K, Thongchote K, Krishnamra N. Prolactin decreases expression of Runx2, osteoprotegerin, and RANKL in primary osteoblasts derived from tibiae of adult female rats.
Can. J. Physiol. Pharmacol. 86: 240-248 (2008).
-
Charoensit P, Kawakami S, Higuchi Y, Hashida M. Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice.
J. Gene Med. 10: 61-69 (2008).
*
-
Charrier-Hisamuddin L, Laboisse CL, Merlin D. ADAM-15: a metalloprotease that mediates inflammation.
FASEB J. 22: 641-653 (2008).
*
-
Charron DJ. New aspects of HLA: perspectives for rheumatoid arthritis.
Clin. Exp. Rheumatol. 10: 293-296 (1992).
-
Chase MA, Wheeler DS, Lierl KM, Hughes VS, Wong HR, Page K. Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism.
J. Immunol. 179: 6318-6324 (2007).
*
-
Chatellard P, Pankiewicz R, Meier E, Durrer L, Sauvage C, Imhof MO. The IE2 promoter/enhancer region from mouse CMV provides high levels of therapeutic protein expression in mammalian cells.
Biotechnol. Bioeng. 96: 106-117 (2007).
*
-
Chatterjee M. Vitamin D and genomic stability.
Mutat. Res. 475: 69-87 (2001).
-
Chatterjee R, Batra J, Kumar A, Mabalirajan U, Nahid S, Niphadkar PV, Ghosh B. Interleukin-10 promoter polymorphisms and atopic asthma in North Indians.
Clin. Exp. Allergy 35: 914-919 (2005).
-
Chaturvedi RK, Adhihetty P, Shukla S, Hennessy T, Calingasan N, Yang L, Starkov A, Kiaei M, Cannella M, Sassone J, Ciammola A, Squitieri F, Beal MF. Impaired PGC-1alpha function in muscle in Huntington's disease.
Hum. Mol. Genet. 18: 3048-3065 (2009).
-
Chaturvedi RK, Flint Beal M. PPAR: a therapeutic target in Parkinson's disease.
J. Neurochem. 106: 506-518 (2008).
*
-
Chatzantoni K, Mouzaki A. Anti-TNF-alpha antibody therapies in autoimmune diseases.
Curr. Top. Med. Chem. 6: 1707-1714 (2006).
-
Chatzigeorgiou A, Lyberi M, Chatzilymperis G, Nezos A, Kamper E. CD40/CD40L signaling and its implication in health and disease.
Biofactors 35: 474-483 (2009).
-
Chatzigeorgiou AE, Lembessis PE, Mylona-Karagianni CF, Tsouvalas EA, Diamanti-Kandarakis E, Kamper EF. CD40 expression and its association with low-grade inflammation in a Greek population of type 1 diabetic juveniles: evidence for differences in CD40 mRNA isoforms expressed by peripheral blood mononuclear cells.
Exp. Clin. Endocrinol. Diabetes Oct 15 [Epub ahead of print] (2009).
-
Chatzikyriakidou A, Georgiou I, Voulgari PV, Papadopoulos CG, Tzavaras T, Drosos AA. Transcription regulatory polymorphism -43T>C in the 5'-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy.
Rheumatol. Int. 27: 1057-1061 (2007).
*
-
Chatzipantelis P, Lazaris AC, Kafiri G, Nonni A, Papadimitriou K, Xiromeritis K, Patsouris ES. CD56 as a useful marker in the regenerative process of the histological progression of primary biliary cirrhosis.
Eur. J. Gastroenterol. Hepatol. 20: 837-842 (2008).
-
Chatzipantelis P, Lazaris AC, Kafiri G, Papadimitriou K, Papathomas TG, Nonni A, Patsouris ES. Cytokeratin-7, cytokeratin-19, and c-Kit: immunoreaction during the evolution stages of primary biliary cirrhosis.
Hepatol. Res. 36: 182-187 (2006).
-
Chaudhuri V, Tayal R, Nayak B, Acharya SK, Panda SK. Occult hepatitis B virus infection in chronic liver disease: full-length genome and analysis of mutant surface promoter.
Gastroenterology 127: 1356-1371 (2004).
*
-
Chaudiere J, Ferrari-Iliou R. Intracellular antioxidants: from chemical to biochemical mechanisms.
Food Chem. Toxicol. 37: 949-962 (1999).
-
Chaung WW, Jacob A, Ji Y, Wang P. Suppression of PGC-1alpha by ethanol: implications of its role in alcohol induced liver injury.
Int. J. Clin. Exp. Med. 1: 161-170 (2008).
*
-
Chava KR, Karpurapu M, Wang D, Bhanoori M, Kundumani-Sridharan V, Zhang Q, Ichiki T, Glasgow WC, Rao GN. CREB-mediated IL-6 expression is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration.
Arterioscler. Thromb. Vasc. Biol. 29: 809-815 (2009).
-
Chavanas S, Mechin MC, Takahara H, Kawada A, Nachat R, Serre G, Simon M. Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6.
Gene 330: 19-27 (2004).
*
-
Chavoshi TM, Moussian B, Uv A. Tissue-autonomous EcR functions are required for concurrent organ morphogenesis in the Drosophila embryo.
Mech. Dev. Jan 18 [Epub ahead of print] (2010).
-
Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files.
Science 294: 1866-1870 (2001).
*
-
Chazouilleres O. Primary sclerosing cholangitis and biliary malignancy: a glimmer of hope?
J. Hepatol. 40: 857-859 (2004).
*
-
Cheadle EJ, Hawkins RE, Batha H, O'Neill AL, Dovedi SJ, Gilham DE. Natural expression of the CD19 antigen impacts the long-term engraftment but not antitumor activity of CD19-specific engineered T cells.
J. Immunol. Jan 20 [Epub ahead of print] (2010).
-
Chearwae W, Bright JJ. 15-Deoxy-delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of Toll-like receptors 4 and 9 in autoimmune T lymphocyte.
J. Clin. Immunol. 28: 558-570 (2008).
*
-
Chearwae W, Bright JJ. PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells.
Br. J. Cancer 99: 2044-2053 (2008).
*
-
Chedid A, Mendenhall CL, Moritz TE. The antigenic heterogeneity of the bile duct epithelium in alcoholic liver disease. VA Cooperative Study Group 275.
Arch. Pathol. Lab. Med. 123: 411-414 (1999).
*
-
Cheema SK, Agarwal-Mawal A, Murray CM, Tucker S. Lack of stimulation of cholesterol ester transfer protein by cholesterol in the presence of a diet high in monounsaturated fatty acids.
J. Lipid Res. 46: 2356-2366 (2005).
*
-
Cheepala SB, Syed Z, Trutschl M, Cvek U, Clifford JL. Retinoids and skin: microarrays shed new light on chemopreventive action of all-trans retinoic acid.
Mol. Carcinog. 46: 634-639 (2007).
*
-
Cheepala SB, Yin W, Syed Z, Gill JN, McMillian A, Kleiner HE, Lynch M, Loganantharaj R, Trutschl M, Cvek U, Clifford JL. Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion.
Mol. Cancer 8: 27 (2009).
*
-
Chelvarajan RL, Liu Y, Popa D, Getchell ML, Getchell TV, Stromberg AJ, Bondada S. Molecular basis of age-associated cytokine dysregulation in LPS-stimulated macrophages.
J. Leukoc. Biol. 79: 1314-1327 (2006).
*
-
Chen A, Zheng S. Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling.
Br. J. Pharmacol. 153: 557-567 (2008).
*
-
Chen AB, Hamamura K, Wang G, Xing W, Mohan S, Yokota H, Liu Y. Model-based comparative prediction of transcription-factor binding motifs in anabolic responses in bone.
Genomics Proteomics Bioinformatics 5: 158-165 (2007).
-
Chen B, Cao S, Zhang Y, Wang X, Liu J, Hui X, Wan Y, Du W, Wang L, Wu K, Fan D. A novel peptide (GX1) homing to gastric cancer vasculature inhibits angiogenesis and cooperates with TNF alpha in anti-tumor therapy.
BMC Cell Biol. 10: 63 (2009).
*
-
Chen B, Fang J, Zhang W, Jin Z, Yu Z, Cai W. Detection of C1236T, G2677T/A, and C3435T polymorphism of MDR1 by amplification refractory mutation system PCR.
J. Clin. Lab. Anal. 23: 110-116 (2009).
-
Chen B, Ma B, Yang S, Xing X, Gu R, Hu Y. DR5 and DcR2 are expressed in human lumbar intervertebral discs.
Spine (Phila. Pa 1976) 34: E677-E681 (2009).
-
Chen B, Zhang Y, Liu G, Guan GJ, Hou XH, Li XG, Liu JL. Effects of valsartan, mycophenolate mofetil and their combined application on TRAIL and nuclear factor-kappaB expression in the kidneys of diabetic rats.
Zhonghua Yi Xue Za Zhi 88: 540-545 (2008).
-
Chen BC, Kuo KK, Chen YH, Liu CH, Tsai LY, Hsu HK, Hsu C. Retinoid X receptor alpha participation in dexamethasone induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver.
Shock 32: 164-171 (2009).
-
Chen C, Bazan NG. Lipid signaling: sleep, synaptic plasticity, and neuroprotection.
Prostaglandins Other Lipid Mediat. 77: 65-76 (2005).
-
Chen C, Cheng X, Dieter MZ, Tanaka Y, Klaassen CD. Activation of cyclic AMP (cAMP)-dependent signaling pathway induces mouse organic anion transporting polypeptide 2 (Oatp2) expression.
Mol. Pharmacol. 71: 1159-1164 (2007).
*
-
Chen C, Xu S, Wang WX, Ding YM, Yu KH, Wang B, Chen XY. Rosiglitazone attenuates the severity of sodium taurocholate-induced acute pancreatitis and pancreatitis-associated lung injury.
Arch. Med. Res. 40: 79-88 (2009).
-
Chen C, Zhang C, Zhuang G, Luo H, Su J, Yin P, Wang J. Decoy receptor 3 overexpression and immunologic tolerance in hepatocellular carcinoma (HCC) development.
Cancer Invest. 26: 965-974 (2008).
-
Chen C, Zhang J, Li J, Huang J, Yang C, Huang G, Shi J. Hydrodynamic-based in vivo transfection of retinoic X receptor-alpha gene can enhance vitamin A-induced attenuation of liver fibrosis in mice.
Liver Int. 24: 679-686 (2004).
*
-
Chen CH, Liao HT, Chen HA, Liu CH, Liang TH, Wang CT, Tsai CY, Chou CT. Human leukocyte antigen-G in ankylosing spondylitis and the response after tumour necrosis factor-alpha blocker therapy.
Rheumatology (Oxford) 49: 264-270 (2010).
-
Chen CH, Nagayama K, Enomoto N, Miyasaka Y, Kurosaki M, Sakamoto N, Maekawa S, Kakinuma S, Ikeda T, Izumi N, Sato C, Watanabe M. Enhancement of mitochondrial gene expression in the liver of primary biliary cirrhosis.
Hepatol. Res. 31: 24-30 (2005).
-
Chen CH, Wang PH, Liu BH, Hsu HH, Mersmann HJ, Ding ST. Serum amyloid A protein regulates the expression of porcine genes related to lipid metabolism.
J. Nutr. 138: 674-679 (2008).
*
-
Chen CY, Kimura H, Landek-Salgado MA, Hagedorn J, Kimura M, Suzuki K, Westra W, Rose NR, Caturegli P. Regenerative potentials of the murine thyroid in experimental autoimmune thyroiditis: role of CD24.
Endocrinology 150: 492-499 (2009).
*
-
Chen D, Hsieh C, Chen K, Chen Y, Lin F, Lan J. Association of interleukin-18 promoter polymorphisms with WHO pathological classes and serum IL-18 levels in Chinese patients with lupus nephritis.
Lupus 18: 29-37 (2009).
*
-
Chen D, Nie M, Fan MW, Bian Z. Anti-inflammatory activity of curcumin in macrophages stimulated by lipopolysaccharides from Porphyromonas gingivalis.
Pharmacology 82: 264-269 (2008).
-
Chen D, Tian T, Wang H, Liu H, Hu Z, Wang Y, Liu Y, Ma H, Fan W, Miao R, Sun W, Wang Y, Qian J, Jin L, Wei Q, Shen H, Huang W, Lu D. Association of human aryl hydrocarbon receptor gene polymorphisms with risk of lung cancer among cigarette smokers in a Chinese population.
Pharmacogenet. Genomics 19: 25-34 (2009).
*
-
Chen DP, Weber SC, Constantinou PS, Ferris TA, Lowe HJ, Butte AJ. Clinical arrays of laboratory measures, or "clinarrays", built from an electronic health record enable disease subtyping by severity.
AMIA Annu. Symp. Proc. 2007: 115-119 (2007).
-
Chen F, Ananthanarayanan M, Emre S, Neimark E, Bull LN, Knisely As A, Strautnieks SS, Thompson RJ, Magid MS, Gordon R, Balasubramanian N, Suchy FJ, Shneider BL. Progressive familial intrahepatic cholestasis, type 1, is associated with decreased farnesoid X receptor activity.
Gastroenterology 126: 756-764 (2004).
*
-
Chen F, Ellis E, Strom SC, Shneider BL. ATPase class I type 8B member 1 and protein kinase C-zeta induce the expression of the canalicular bile salt export pump in human hepatocytes.
Pediatr. Res. Oct 5 [Epub ahead of print] (2009).
-
Chen F, Ma L, Al-Ansari N, Shneider B. The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter.
J. Biol. Chem. 276: 38703-38714 (2001).
*
-
Chen F, Ohashi N, Li W, Eckman C, Nguyen JH. Disruptions of occludin and claudin-5 in brain endothelial cells in vitro and in brains of mice with acute liver failure.
Hepatology 50: 1914-1923 (2009).
-
Chen F, Wollmer MA, Hoerndli F, Munch G, Kuhla B, Rogaev EI, Tsolaki M, Papassotiropoulos A, Gotz J. Role for glyoxalase I in Alzheimer's disease.
Proc. Natl. Acad. Sci. U.S.A. 101: 7687-7692 (2004).
*
-
Chen FL, Yang ZH, Wang XC, Liu Y, Yang YH, Li LX, Liang WC, Zhou WB, Hu RM. Adipophilin affects the expression of TNF-alpha, MCP-1, and IL-6 in THP-1 macrophages.
Mol. Cell. Biochem. Oct 23 [Epub ahead of print] (2009).
*
-
Chen G, Li J, Ochani M, Rendon-Mitchell B, Qiang X, Susarla S, Ulloa L, Yang H, Fan S, Goyert SM, Wang P, Tracey KJ, Sama AE, Wang H. Bacterial endotoxin stimulates macrophages to release HMGB1 partly through CD14- and TNF-dependent mechanisms.
J. Leukoc. Biol. 76: 994-1001 (2004).
*
-
Chen G, Shi J, Ding Y, Yin H, Hang C. Progesterone prevents traumatic brain injury-induced intestinal nuclear factor kappa B activation and proinflammatory cytokines expression in male rats.
Mediators Inflamm. 2007: 93431 (2007).
*
-
Chen G, Shi J, Hu Z, Hang C. Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine.
Mediators Inflamm. 2008: 716458 (2008).
*
-
Chen G, Wang S, Bie P, Li X, Dong J. Endogenous bile salts are associated with bile duct injury in the rat liver transplantation model.
Transplantation 87: 330-339 (2009).
-
Chen G, Zhang Y, Lu D, Li NQ, Ross AC. Retinoids synergize with insulin to induce hepatic Gck Expression.
Biochem. J. 419: 645-653 (2009).
*
-
Chen GG, Ho RL, Wong J, Lee KF, Lai PB. Single nucleotide polymorphism in the promoter region of human alpha-fetoprotein (AFP) gene and its significance in hepatocellular carcinoma (HCC).
Eur. J. Surg. Oncol. 33: 882-886 (2007).
-
Chen GG, Xu H, Lee JF, Subramaniam M, Leung KL, Wang SH, Chan UP, Spelsberg TC. 15-Hydroxy-eicosatetraenoic acid arrests growth of colorectal cancer cells via a peroxisome proliferator-activated receptor gamma-dependent pathway.
Int. J. Cancer 107: 837-843 (2003).
*
-
Chen GY, Sakuma K, Kannagi R. Significance of NF-kappa B/GATA axis in tumor necrosis factor-alpha-induced expression of 6-sulfated cell-recognition glycans in human T-lymphocytes.
J. Biol. Chem. 283: 34563-34570 (2008).
*
-
Chen H, Cowan MJ, Hasday JD, Vogel SN, Medvedev AE. Tobacco smoking inhibits expression of proinflammatory cytokines and activation of IL-1R-associated kinase, p38, and NF-kappaB in alveolar macrophages stimulated with TLR2 and TLR4 agonists.
J. Immunol. 179: 6097-6106 (2007).
*
-
Chen H, Hewison M, Adams JS. Functional characterization of heterogeneous nuclear ribonuclear protein C1/C2 in vitamin D resistance: a novel response element binding protein.
J. Biol. Chem. 281: 39114-39120 (2006).
*
-
Chen H, Wang W, Xie H, Xu X, Wu J, Jiang Z, Zhang M, Zhou L, Zheng S. A pathogenic role of IL-17 at the early stage of corneal allograft rejection.
Transpl. Immunol. 21: 155-161 (2009).
-
Chen HJ, Lin SP, Lee HC, Chen CP, Chiu NC, Hung HY, Chern SR, Chuang CK. Cystic fibrosis with homozygous R553X mutation in a Taiwanese child.
J. Hum. Genet. 50: 674-678 (2005).
*
-
Chen HL, Chen HL, Liu YJ, Feng CH, Wu CY, Shyu MK, Yuan RH, Chang MH. Developmental expression of canalicular transporter genes in human liver.
J. Hepatol. 43: 472-477 (2005).
*
-
Chen HL, Wang R, Chen HL, Hwu WL, Jeng YM, Chang MH, Ling V. Bone marrow transplantation results in donor-derived hepatocytes in an animal model of inherited cholestatic liver disease.
J. Biomed. Sci. 15: 615-622 (2008).
*
-
Chen HO, Chen ZJ, Qiu Y, Qiu XS, Cao XB, Liu Z, Li WG. Investigation on the association between estrogen beta receptor gene polymorphisms and the susceptibility of adolescent idiopathic scoliosis.
Stud. Health Technol. Inform. 140: 322 (2008).
-
Chen IH, Lai YL, Wu CL, Chang YF, Chu CC, Tsai IF, Sun FJ, Lu YT. Immune impairment in patients with terminal cancers: influence of cancer treatments and cytomegalovirus infection.
Cancer Immunol. Immunother. Aug 15 [Epub ahead of print] (2009).
*
-
Chen J, Carcamo JM, Golde DW. The alpha subunit of the granulocyte-macrophage colony-stimulating factor receptor interacts with c-Kit and inhibits c-Kit signaling.
J. Biol. Chem. 281: 22421-22426 (2006).
*
-
Chen J, Mehta JL. Angiotensin II-mediated oxidative stress and pro-collagen-1 expression in cardiac fibroblasts: blockade by pravastatin and pioglitazone.
Am. J. Physiol. Heart Circ. Physiol. 291: H1738-H1745 (2006).
*
-
Chen J, Rao JN, Zou T, Liu L, Marasa BS, Xiao L, Zeng X, Turner DJ, Wang JY. Polyamines are required for expression of Toll-like receptor 2 modulating intestinal epithelial barrier integrity.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G568-G576 (2007).
*
-
Chen J, Raymond K. Treatment effect of rifampicin on cholestasis.
The Internet Journal of Pharmacology Vol. 4 (http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijpharm/vol4n2/colestasis.xml) (2006). *
-
Chen J, Xiao L, Rao JN, Zou T, Liu L, Bellavance E, Gorospe M, Wang JY. JunD represses transcription and translation of the tight junction protein zona occludens-1 modulating intestinal epithelial barrier function.
Mol. Biol. Cell 19: 3701-3712 (2008).
*
-
Chen J, Yang W, Yu C, Li Y. Autoimmune regulator initiates the expression of promiscuous genes in thymic epithelial cells.
Immunol. Invest. 37: 203-214 (2008).
*
-
Chen JY, Wang CM, Ma CC, Chow YH, Luo SF. The -844C/T polymorphism in the Fas ligand promoter associates with Taiwanese SLE.
Genes Immun. 6: 123-128 (2005).
*
-
Chen K, Wei Y, Alter A, Sharp GC, Braley-Mullen H. Chemokine expression during development of fibrosis versus resolution in a murine model of granulomatous experimental autoimmune thyroiditis.
J. Leukoc. Biol. 78: 716-724 (2005).
*
-
Chen K, Wei Y, Sharp GC, Braley-Mullen H. Decreasing TNF-alpha results in less fibrosis and earlier resolution of granulomatous experimental autoimmune thyroiditis.
J. Leukoc. Biol. 81: 306-314 (2007).
*
-
Chen L, Borozan I, Milkiewicz P, Sun J, Meng X, Coltescu C, Edwards AM, Ostrowski MA, Guindi M, Heathcote EJ, McGilvray ID. Gene expression profiling of early primary biliary cirrhosis: possible insights into the mechanism of action of ursodeoxycholic acid.
Liver Int. 28: 997-1010 (2008).
*
-
Chen L, Borozan I, Sun J, Guindi M, Fischer S, Feld J, Anand N, Heathcote J, Edwards AM, McGilvray ID. Cell-type specific gene expression signature in liver underlies response to interferon therapy in chronic hepatitis C infection.
Gastroenterology Nov 6 [Epub ahead of print] (2009).
*
-
Chen L, Hu L, Chan TH, Tsao GS, Xie D, Huo KK, Fu L, Ma S, Zheng BJ, Guan XY. Chromodomain helicase/adenosine triphosphatase DNA binding protein 1-like (CHD1l) gene suppresses the nucleus-to-mitochondria translocation of nur77 to sustain hepatocellular carcinoma cell survival.
Hepatology 50: 122-129 (2009).
-
Chen L, Khillan JS. Promotion of feeder independent self-renewal of embryonic stem cells by retinol (vitamin A).
Stem Cells 26: 1858-1864 (2008).
*
-
Chen L, Wong C. Estrogen-related receptor alpha inverse agonist enhances basal glucose uptake in myotubes through reactive oxygen species.
Biol. Pharm. Bull. 32: 1199-1203 (2009).
*
-
Chen L, Yan HX, Yang W, Hu L, Yu LX, Liu Q, Li L, Huang DD, Ding J, Shen F, Zhou WP, Wu MC, Wang HY. The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma.
J. Hepatol. 50: 358-369 (2009).
-
Chen LP, Cai M, Zhang QH, Li ZL, Qian YY, Bai HW, Wei X, Shi BY, Dong JH. Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharide.
Dig. Dis. Sci. 54: 547-554 (2009).
*
-
Chen LS, Wei JB, Zhou YC, Zhang S, Liang JL, Cao YF, Tang ZJ, Zhang XL, Gao F. Genetic alterations and expression of inhibitor of growth 1 in human sporadic colorectal cancer.
World J. Gastroenterol. 11: 6120-6124 (2005).
*
-
Chen LW, Chang WJ, Chen PH, Liu WC, Hsu CM. TLR ligand decreases mesenteric ischemia and reperfusion injury-induced gut damage through TNF-alpha signaling.
Shock 30: 563-570 (2008).
-
Chen LW, Huang HL, Lee IT, Hsu CM, Lu PJ. Hypertonic saline enhances host defense to bacterial challenge by augmenting Toll-like receptors.
Crit. Care Med. 34: 1758-1768 (2006).
-
Chen M, Beaven SW, Tontonoz P. Identification and characterization of two alternatively spliced transcript variants of human liver X receptor alpha.
J. Lipid Res. 46: 2570-2579 (2005).
*
-
Chen M, Chen G, Nie H, Zhang X, Niu X, Zang YC, Skinner SM, Zhang JZ, Killian JM, Hong J. Regulatory effects of IFN-beta on production of osteopontin and IL-17 by CD4+ T cells in MS.
Eur. J. Immunol. 39: 2525-2536 (2009).
*
-
Chen M, Chen ZQ, Cui PG, Yao X, Li YM, Li AS, Gong JQ, Cao YH. The methylation pattern of p16INK4a gene promoter in psoriatic epidermis and its clinical significance.
Br. J. Dermatol. 158: 987-993 (2008).
*
-
Chen N, Bezzina R, Hinch E, Lewandowski PA, Cameron-Smith D, Mathai ML, Jois M, Sinclair AJ, Begg DP, Wark JD, Weisinger HS, Weisinger RS. Green tea, black tea, and epigallocatechin modify body composition, improve glucose tolerance, and differentially alter metabolic gene expression in rats fed a high-fat diet.
Nutr. Res. 29: 784-793 (2009).
-
Chen N, Chen X, Huang R, Zeng H, Gong J, Meng W, Lu Y, Zhao F, Wang L, Zhou Q. BCL-xL is a target gene regulated by hypoxia-inducible factor-1-alpha.
J. Biol. Chem. 284: 10004-10012 (2009).
*
-
Chen P, Li C, Pang W, Zhao Y, Dong W, Wang S, Zhang J. The protective role of Per2 against carbon tetrachloride-induced hepatotoxicity.
Am. J. Pathol. 174: 63-70 (2009).
*
-
Chen PJ, Padgett WT, Moore T, Winnik W, Lambert GR, Thai SF, Hester SD, Nesnow S. Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo.
Toxicol. Appl. Pharmacol. 234: 143-155 (2009).
*
-
Chen PW, Mellon JK, Mayhew E, Wang S, He YG, Hogan N, Niederkorn JY. Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.
Exp. Eye Res. 85: 617-625 (2007).
-
Chen Q, Ross AC. Vitamin A and immune function: retinoic acid modulates population dynamics in antigen receptor and CD38-stimulated splenic B cells.
Proc. Natl. Acad. Sci. U.S.A. 102: 14142-14149 (2005).
*
-
Chen Q, Sun X, Chen J, Cheng L, Wang J, Wang Y, Sun Z. Direct rosiglitazone action on steroidogenesis and proinflammatory factor production in human granulosa-lutein cells.
Reprod. Biol. Endocrinol. 7: 147 (2009).
-
Chen Q, Yan CQ, Liu FJ, Tong J, Miao SL, Chen JP. Overexpression of the PDCD2-like gene results in Inhibited TNF-alpha production in activated Daudi cells.
Hum. Immunol. 69: 259-265 (2008).
-
Chen Q, Zhao Y, Cheng Z, Xu Y, Yu C. Establishment of a cell-based assay for examining the expression of tumor necrosis factor alpha (TNF-alpha) gene.
Appl. Microbiol. Biotechnol. 80: 357-363 (2008).
*
-
Chen R, Yi EC, Donohoe S, Pan S, Eng J, Cooke K, Crispin DA, Lane Z, Goodlett DR, Bronner MP, Aebersold R, Brentnall TA. Pancreatic cancer proteome: the proteins that underlie invasion, metastasis, and immunologic escape.
Gastroenterology 129: 1187-1197 (2005).
*
-
Chen S. Highly pure phospholipids based brain docosahexaenoic acid transporters.
Recent Pat. CNS Drug Discov. Oct 15 [Epub ahead of print] (2009).
-
Chen S, Beaton D, Nguyen N, Senekeo-Effenberger K, Brace-Sinnokrak E, Argikar U, Remmel R, Trottier J, Barbier O, Ritter JK, Tukey RH. Tissue specific, inducible, and hormonal control of the human UDP-glucuronosyltransferase-1 (UGT1) locus.
J. Biol. Chem. 280: 37547-37557 (2005).
*
-
Chen S, Ding JH, Bekeredjian R, Yang BZ, Shohet RV, Johnston SA, Hohmeier HE, Newgard CB, Grayburn PA. Efficient gene delivery to pancreatic islets with ultrasonic microbubble destruction technology.
Proc. Natl. Acad. Sci. U.S.A. 103: 8469-8474 (2006).
*
-
Chen S, Olsen K, Grigsby C, Gardner DG. Vitamin D activates type A natriuretic peptide receptor gene transcription in inner medullary collecting duct cells.
Kidney Int. 72: 300-306 (2007).
*
-
Chen S, Wang K, Wan YJ. Retinoids activate RXR/CAR-mediated pathway and induce CYP3A.
Biochem. Pharmacol. 79: 270-276 (2010).
*
-
Chen S, Wong MH, Schulte DJ, Arditi M, Michelsen KS. Differential expression of Toll-like receptor 2 (TLR2) and responses to TLR2 ligands between human and murine vascular endothelial cells.
J. Endotoxin Res. 13: 281-296 (2007).
*
-
Chen SJ, Rader DJ, Tazelaar J, Kawashiri M, Gao G, Wilson JM. Prolonged correction of hyperlipidemia in mice with familial hypercholesterolemia using an adeno-associated viral vector expressing very-low-density lipoprotein receptor.
Mol. Ther. 2: 256-261 (2000).
-
Chen SJ, Wang YL, Kao JH, Wu SF, Lo WT, Wu CC, Tao PL, Wang CC, Chang DM, Sytwu HK. Decoy receptor 3 ameliorates experimental autoimmune encephalomyelitis by directly counteracting local inflammation and downregulating Th17 cells.
Mol. Immunol. 47: 567-574 (2009).
*
-
Chen SW, Chen YX, Zhang XR, Qian H, Chen WZ, Xie WF. Targeted inhibition of platelet-derived growth factor receptor-beta subunit in hepatic stellate cells ameliorates hepatic fibrosis in rats.
Gene Ther. 15: 1424-1435 (2008).
-
Chen SW, Zhang XR, Wang CZ, Chen WZ, Xie WF, Chen YX. RNA interference targeting the platelet-derived growth factor receptor beta subunit ameliorates experimental hepatic fibrosis in rats.
Liver Int. 28: 1446-1457 (2008).
*
-
Chen W, Cai SY, Xu S, Denson L, Soroka C, Boyer JL. Nuclear receptors RXRalpha:RARalpha are repressors for human MRP3 expression.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1221-G1227 (2007).
*
-
Chen W, Chen G, Head DL, Mangelsdorf DJ, Russell DW. Enzymatic reduction of oxysterols impairs LXR signaling in cultured cells and the livers of mice.
Cell. Metab. 5: 73-79 (2007).
*
-
Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ. Glucocorticoid receptor phosphorylation differentially affects target gene expression.
Mol. Endocrinol. 22: 1754-1766 (2008).
*
-
Chen W, Esselman WJ, Jump DB, Busik JV. Anti-inflammatory effect of docosahexaenoic acid on cytokine-induced adhesion molecule expression in human retinal vascular endothelial cells.
Invest. Ophthalmol. Vis. Sci. 46: 4342-4347 (2005).
*
-
Chen W, Gluud C. Bile acids for liver-transplanted patients.
Cochrane Database Syst. Rev. 3: CD005442 (2005).
*
-
Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, McGrady G, Wahl SM. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.
J. Exp. Med. 198: 1875-1886 (2003).
*
-
Chen W, Jump DB, Esselman WJ, Busik JV. Inhibition of cytokine signaling in human retinal endothelial cells through modification of caveolae/lipid rafts by docosahexaenoic acid.
Invest. Ophthalmol. Vis. Sci. 48: 18-26 (2007).
*
-
Chen W, Li YM, Yu MH. Astragalus polysaccharides: an effective treatment for diabetes prevention in NOD mice.
Exp. Clin. Endocrinol. Diabetes 116: 468-474 (2008).
-
Chen W, Liang X, Peterson AJ, Munn DH, Blazar BR. The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.
J. Immunol. 181: 5396-5404 (2008).
*
-
Chen W, Owsley E, Yang Y, Stroup D, Chiang JY. Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids.
J. Lipid Res. 42: 1402-1412 (2001).
*
-
Chen W, Yan C, Hou J, Pu J, Ouyang J, Wen D. ATRA enhances bystander effect of suicide gene therapy in the treatment of prostate cancer.
Urol. Oncol. 26: 397-405 (2008).
-
Chen WC, Chiang BL, Liu HE, Leu SJ, Lee YL. Defective functions of circulating CD4(+)CD25(+) and CD4(+)CD25(-) T cells in patients with chronic ordinary urticaria.
J. Dermatol. Sci. 51: 121-130 (2008).
-
Chen WD, Wang YD, Zhang L, Shiah S, Wang M, Yang F, Yu D, Forman BM, Huang W. Farnesoid X receptor alleviates age-related proliferation defects in regenerating mouse livers by activating forkhead box m1b transcription.
Hepatology Oct 22 [Epub ahead of print] (2009).
*
-
Chen WH, Wang XX, Lin W, He XW, Wu ZQ, Lin Y, Hu SN, Wang XN. Analysis of 10,000 ESTs from lymphocytes of the cynomolgus monkey to improve our understanding of its immune system.
BMC Genomics 7: 82 (2006).
*
-
Chen WJ, Li H, Jia Y, Zhang L, Lu ML, Li MY, Jiang ZH. Study of the construction and function of an eukaryotic expression plasmid of immunotoxin DT390 gene.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 22: 299-301 (2006).
-
Chen WS, Lin KC, Chen CH, Liao HT, Wang HP, Li WY, Lee HT, Tsai CY, Chou CT. Autoantibody and biopsy grading are associated with expression of ICAM-1, MMP-3, and TRAIL in salivary gland mononuclear cells of Chinese patients with Sjogren's syndrome.
J. Rheumatol. 36: 989-996 (2009).
-
Chen WY, Chang MS. IL-20 is regulated by hypoxia-inducible factor and up-regulated after experimental ischemic stroke.
J. Immunol. 182: 5003-5012 (2009).
-
Chen X, Chen F, Liu S, Glaeser H, Dawson PA, Hofmann AF, Kim RB, Shneider BL, Pang KS. Transactivation of rat ASBT and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor (VDR).
Mol. Pharmacol. 69: 1913-1923 (2006).
*
-
Chen X, El Gazzar M, Yoza BK, McCall CE. The NF-kappaB factor RelB and histone H3 lysine methyltransferase G9a directly interact to generate epigenetic silencing in endotoxin tolerance.
J. Biol. Chem. 284: 27857-27865 (2009).
*
-
Chen X, Jensen PE. MHC class II antigen presentation and immunological abnormalities due to deficiency of MHC class II and its associated genes.
Exp. Mol. Pathol. 85: 40-44 (2008).
*
-
Chen X, Liu Z, Yue Q, Liu H, Wu Y, Li J. The expression of TNF-alpha and ICAM-1 in lesions of lichen planus and its implication.
J. Huazhong Univ. Sci. Technolog. Med. Sci. 27: 739-741 (2007).
-
Chen X, Maiti S, Zhang J, Chen G. Nuclear receptor interactions in methotrexate induction of human dehydroepiandrosterone sulfotransferase (hSULT2A1).
J. Biochem. Mol. Toxicol. 20: 309-317 (2006).
*
-
Chen X, Matthews J, Zhou L, Pelton P, Liang Y, Xu J, Yang M, Cryan E, Rybczynski P, Demarest K. Improvement of dyslipidemia, insulin sensitivity, and energy balance by a peroxisome proliferator-activated receptor alpha agonist.
Metabolism 57: 1516-1525 (2008).
*
-
Chen X, Sebastian BM, Tang H, McMullen MM, Axhemi A, Jacobsen DW, Nagy LE. Taurine supplementation prevents ethanol-induced decrease in serum adiponectin and reduces hepatic steatosis in rats.
Hepatology 49: 1554-1562 (2009).
-
Chen X, Wan J, Liu J, Xie W, Diao X, Xu J, Zhu B, Chen Z. Increased IL-17-producing cells correlate with poor survival and lymphangiogenesis in NSCLC patients.
Lung Cancer Dec 16 [Epub ahead of print] (2009).
-
Chen X, Xun K, Chen L, Wang Y. TNF-alpha, a potent lipid metabolism regulator.
Cell. Biochem. Funct. 27: 407-416 (2009).
*
-
Chen XD, Chen YL, Wang SB, Lei T, Gan L, Yang ZQ. Molecular characterization and functional analysis of porcine macrophage migration inhibitory factor (MIF) gene.
Cytokine Jan 19 [Epub ahead of print] (2010).
-
Chen XL, Dodd G, Kunsch C. Sulforaphane inhibits TNF-alpha-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells.
Inflamm. Res. 58: 513-521 (2009).
*
-
Chen XM. MicroRNA signatures in liver diseases.
World J. Gastroenterol. 15: 1665-1672 (2009).
*
-
Chen XN, Meng QY, Bao AM, Swaab DF, Wang GH, Zhou JN. The involvement of retinoic acid receptor-alpha in corticotropin-releasing hormone gene expression and affective disorders.
Biol. Psychiatry 66: 832-839 (2009).
-
Chen XQ, Yu YC, Deng HH, Sun JZ, Dai Z, Wu YW, Yang M. Plasma IL-17A is increased in new-onset SLE patients and associated with disease activity.
J. Clin. Immunol. Jan 28 [Epub ahead of print] (2010).
*
-
Chen XY, Yan WH, Lin A, Xu HH, Zhang JG, Wang XX. The 14 bp deletion polymorphisms in HLA-G gene play an important role in the expression of soluble HLA-G in plasma.
Tissue Antigens 72: 335-341 (2008).
*
-
Chen Y, Akirav EM, Chen W, Henegariu O, Moser B, Desai D, Shen JM, Webster JC, Andrews RC, Mjalli AM, Rothlein R, Schmidt AM, Clynes R, Herold KC. RAGE ligation affects T cell activation and controls T cell differentiation.
J. Immunol. 181: 4272-4278 (2008).
*
-
Chen Y, Chen Y, Liu WL, Zhou TH, Cai JT, Du Q, Wang LJ, Wu JG, Si JM. Therapeutic effects of rectal administration of muscovite on experimental colitis in rats.
J. Gastroenterol. Hepatol. 24: 912-919 (2009).
*
-
Chen Y, Chong MM, Darwiche R, Thomas HE, Kay TW. Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency.
Am. J. Pathol. 165: 913-921 (2004).
*
-
Chen Y, Coulter S, Jetten AM, Goldstein JA. Identification of human CYP2C8 as a retinoid-related orphan nuclear receptor target gene.
J. Pharmacol. Exp. Ther. 329: 192-201 (2009).
*
-
Chen Y, Gan H, Ouyang Q, Xu D, Pan Y. The effects of anti-inflammatory on activation of nuclear factor-kappaB and expression of cell adhesion molecules in patients with ulcerative colitis.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi 21: 732-736 (2004).
-
Chen Y, Goldstein JA. The transcriptional regulation of the human CYP2C genes.
Curr. Drug Metab. 10: 567-578 (2009).
-
Chen Y, Hu X, Wei LN. Molecular interaction of retinoic acid receptors with coregulators PCAF and RIP140.
Mol. Cell. Endocrinol. 226: 43-50 (2004).
-
Chen Y, Langrish CL, McKenzie B, Joyce-Shaikh B, Stumhofer JS, McClanahan T, Blumenschein W, Churakovsa T, Low J, Presta L, Hunter CA, Kastelein RA, Cua DJ. Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis.
J. Clin. Invest. 116: 1317-1326 (2006).
*
-
Chen Y, Muller JD. Determining the stoichiometry of protein heterocomplexes in living cells with fluorescence fluctuation spectroscopy.
Proc. Natl. Acad. Sci. U.S.A. 104: 3147-3152 (2007).
*
-
Chen Y, Perry D, Boackle SA, Sobel ES, Molina H, Croker BP, Morel L. Several genes contribute to the production of autoreactive B and T cells in the murine lupus susceptibility locus Sle1c.
J. Immunol. 175: 1080-1089 (2005).
*
-
Chen Y, Stankovic R, Cullen KM, Meininger V, Garner B, Coggan S, Grant R, Brew BJ, Guillemin GJ. The kynurenine pathway and inflammation in amyotrophic lateral sclerosis.
Neurotox. Res. Nov 18 [Epub ahead of print] (2009).
*
-
Chen Y, Tang Y, Wang MT, Zeng S, Nie D. Human pregnane X receptor and resistance to chemotherapy in prostate cancer.
Cancer Res. 67: 10361-10367 (2007).
*
-
Chen Y, Wang YN, Zhou HH. Progress in the study of heterogeneous nuclear ribonucleoprotein and its relation with diseases.
Sheng Li Ke Xue Jin Zhan 39: 109-113 (2008).
-
Chen Y, Wei H, Sun R, Dong Z, Zhang J, Tian Z. Increased susceptibility to liver injury in hepatitis B virus transgenic mice involves NKG2D-ligand interaction and natural killer cells.
Hepatology 46: 706-715 (2007).
*
-
Chen Y, Yang C, Xie Z, Zou L, Ruan Z, Zhang X, Tang Y, Fei L, Jia Z, Wu Y. Expression of the novel co-stimulatory molecule B7-H4 by renal tubular epithelial cells.
Kidney Int. 70: 2092-2099 (2006).
*
-
Chen Y, Zhang J, Guo G, Ruan Z, Jiang M, Wu S, Guo S, Fei L, Tang Y, Yang C, Jia Z, Wu Y. Induced B7-H1 expression on human renal tubular epithelial cells by the sublytic terminal complement complex C5b-9.
Mol. Immunol. 46: 375-383 (2009).
*
-
Chen Y, Zhu J, Lum PY, Yang X, Pinto S, Macneil DJ, Zhang C, Lamb J, Edwards S, Sieberts SK, Leonardson A, Castellini LW, Wang S, Champy MF, Zhang B, Emilsson V, Doss S, Ghazalpour A, Horvath S, Drake TA, Lusis AJ, Schadt EE. Variations in DNA elucidate molecular networks that cause disease.
Nature 452: 429-435 (2008).
*
-
Chen YB, Yan ML, Gong JP, Xia RP, Liu LX, Li N, Lu SC, Zhang JG, Zeng DB, Xie JG, Yang JY, Yan LN. Establishment of hepatocellular carcinoma multidrug resistant monoclone cell line HepG2/mdr1.
Chin. Med. J. (Engl.) 120: 703-707 (2007).
-
Chen YH, Lee MF, Tsai JJ, Wu HJ, Hwang GY. Specific IgE and IgG responses and cytokine profile in subjects with allergic reactions to biting midge Forcipomyia taiwana.
Int. Arch. Allergy Immunol. 150: 66-74 (2009).
-
Chen YH, Lin SJ, Chen YL, Liu PL, Chen JW. Anti-inflammatory effects of different drugs/agents with antioxidant property on endothelial expression of adhesion molecules.
Cardiovasc. Hematol. Disord. Drug Targets 6: 279-304 (2006).
-
Chen YH, Wang JP, Wang H, Sun MF, Wei LZ, Wei W, Xu DX. Lipopolysaccharide treatment downregulates the expression of the pregnane X receptor, cyp3a11 and mdr1a genes in mouse placenta.
Toxicology 211: 242-252 (2005).
*
-
Chen YH, Yang CK, Xia M, Ou CY, Stallcup MR. Role of GAC63 in transcriptional activation mediated by beta-catenin.
Nucleic Acids Res. 35: 2084-2092 (2007).
*
-
Chen YM, Chen LY, Wong FH, Lee CM, Chang TJ, Yang-Feng TL. Genomic structure, expression, and chromosomal localization of the human glycine N-methyltransferase gene.
Genomics 66: 43-47 (2000).
*
-
Chen YM, Shiu JY, Tzeng SJ, Shih LS, Chen YJ, Lui WY, Chen PH. Characterization of glycine-N-methyltransferase-gene expression in human hepatocellular carcinoma.
Int. J. Cancer 75: 787-793 (1998).
*
-
Chen YP, Pfab T, Slowinski T, Richter CM, Godes M, Hocher B. Impact of genetic variation of tumor necrosis factor-alpha on gestational hypertension.
Chin. Med. J. (Engl.) 119: 719-724 (2006).
*
-
Chen YT, Li S, Nikulina K, Porco T, Gallup M, McNamara N. Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye.
Mol. Vis. 15: 563-576 (2009).
*
-
Chen YW, Shi R, Geraci N, Shrestha S, Gordish-Dressman H, Pachman LM. Duration of chronic inflammation alters gene expression in muscle from untreated girls with juvenile dermatomyositis.
BMC Immunol. 9: 43 (2008).
*
-
Chen Z, de Kauwe AL, Keech C, Wijburg O, Simpfendorfer K, Alexander WS, McCluskey J. Humanized transgenic mice expressing HLA DR4-DQ3 haplotype: reconstitution of phenotype and HLA-restricted T-cell responses.
Tissue Antigens 68: 210-219 (2006).
*
-
Chen Z, Freedman MS. CD16(+) gammadelta T cells mediate antibody dependent cellular cytotoxicity: potential mechanism in the pathogenesis of multiple sclerosis.
Clin. Immunol. 128: 219-227 (2008).
*
-
Chen Z, Laurence A, O'Shea JJ. Signal transduction pathways and transcriptional regulation in the control of Th17 differentiation.
Semin. Immunol. 19: 400-408 (2007).
*
-
Chen Z, Marsden PA, Gorczynski RM. Role of a distal enhancer in the transcriptional responsiveness of the human CD200 gene to interferon-gamma and tumor necrosis factor-alpha.
Mol. Immunol. 46: 1951-1963 (2009).
*
-
Chen Z, O'Shea JJ. Th17 cells: a new fate for differentiating helper T cells.
Immunol. Res. 41: 87-102 (2008).
*
-
Chen Z, O'Shea JJ. Regulation of IL-17 production in human lymphocytes.
Cytokine 41: 71-78 (2008).
-
Chen Z, Stockton J, Mathis D, Benoist C. Modeling CTLA4-linked autoimmunity with RNA interference in mice.
Proc. Natl. Acad. Sci. U.S.A. 103: 16400-16405 (2006).
*
-
Chen Z, Zhou Z, Chen X, Xu J, Liu A, Du W, Gu D, Ge J, Guo Z, Wang X, Dong X, Ren Q, Yang R. Single nucleotide polymorphism in DNMT3B promoter and the risk for idiopathic thrombocytopenic purpura in Chinese population.
J. Clin. Immunol. 28: 399-404 (2008).
*
-
Chen ZP, Shemshedini L, Durand B, Noy N, Chambon P, Gronemeyer H. Pure and functionally homogeneous recombinant retinoid X receptor.
J. Biol. Chem. 269: 25770-25776 (1994).
*
-
Cheng B, Zheng Y, Guo X, Wang Y, Liu C. Hepatitis B viral X protein alters the biological features and expressions of DNA repair enzymes in LO2 cells.
Liver Int. 30: 319-326 (2010).
-
Cheng CK, Li L, Cheng SH, Lau KM, Chan NP, Wong RS, Shing MM, Li CK, Ng MH. Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia.
Blood 112: 3391-3402 (2008).
*
-
Cheng D, Kim WS, Garner B. Regulation of alpha-synuclein expression by liver X receptor ligands in vitro.
Neuroreport 19: 1685-1689 (2008).
-
Cheng HH, Hu XJ, Ruan QR. Dehydroepiandrosterone anti-atherogenesis effect is not via its conversion to estrogen.
Acta Pharmacol. Sin. 30: 42-53 (2009).
-
Cheng HT, Chen JY, Huang YC, Chang HC, Hung WC. Functional role of VDR in the activation of p27(Kip1) by the VDR/Sp1 complex.
J. Cell. Biochem. 98: 1450-1456 (2006).
*
-
Cheng J, Kapranov P, Drenkow J, Dike S, Brubaker S, Patel S, Long J, Stern D, Tammana H, Helt G, Sementchenko V, Piccolboni A, Bekiranov S, Bailey DK, Ganesh M, Ghosh S, Bell I, Gerhard DS, Gingeras TR. Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution.
Science 308: 1149-1154 (2005).
*
-
Cheng J, Tu Y, Li J, Huang C, Liu Z, Liu D. A study on the expression of interleukin (IL)-10 and IL-12 P35, P40 mRNA in the psoriatic lesions.
J. Tongji. Med. Univ. 21: 86-88 (2001).
-
Cheng JB, Motola DL, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW. Identification and characterization of CYP2R1, a microsomal vitamin D 25-hydroxylase.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 21. June 18-19 (2004). *
-
Cheng JB, Levine MA, Bell NH, Mangelsdorf DJ, Russell DW. Genetic evidence that the human CYP2R1 enzyme is a key vitamin D 25-hydroxylase.
Proc. Natl. Acad. Sci. U.S.A. 101: 7711-7715 (2004).
*
-
Cheng JB, Motola DL, Mangelsdorf DJ, Russell DW. De-orphanization of cytochrome P450 2R1: a microsomal vitamin D 25-hydroxylase.
J. Biol. Chem. 278: 38084-38093 (2003).
*
-
Cheng JF, Zapf J, Takedomi K, Fukushima C, Ogiku T, Zhang SH, Yang G, Sakurai N, Barbosa M, Jack R, Xu K. Combination of virtual screening and high throughput gene profiling for identification of novel liver X receptor modulators.
J. Med. Chem. 51: 2057-2061 (2008).
*
-
Cheng JY, Meng CL, Chao CF, Gau SD, Lin JC. Human papillomavirus 16 DNA in NIH3T3 cells transformed by colonic cancer cellular DNA.
Gut 34: 1710-1713 (1993).
*
-
Cheng K, Yang N, Mahato RI. TGF-1 gene silencing for treating liver fibrosis.
Mol. Pharm. 6: 772-779 (2009).
*
-
Cheng MH, Shum AK, Anderson MS. What's new in the Aire?
Trends Immunol. 28: 321-327 (2007).
*
-
Cheng PT, Mukherjee R. PPARs as targets for metabolic and cardiovascular diseases.
Mini. Rev. Med. Chem. 5: 741-753 (2005).
-
Cheng S, Clancy CJ, Checkley MA, Handfield M, Hillman JD, Progulske-Fox A, Lewin AS, Fidel PL, Nguyen MH. Identification of Candida albicans genes induced during thrush offers insight into pathogenesis.
Mol. Microbiol. 48: 1275-1288 (2003).
*
-
Cheng TF, Brzostek S, Ando O, Van Scoy S, Kumar KP, Reich NC. Differential activation of IFN regulatory factor (IRF)-3 and IRF-5 transcription factors during viral infection.
J. Immunol. 176: 7462-7470 (2006).
*
-
Cheng W, Cheng NS, Xiong XZ, Xia QJ, Chen OY, Yan NH, Jing J. Expression of PPAR-gamma in human hilar bile duct carcinoma cell line QBC939 and the effects of PPAR-Y activated by its ligand on the growth of QBC939.
Sichuan Da Xue Xue Bao Yi Xue Ban 37: 745-749 (2006).
-
Cheng X, Buckley D, Klaassen CD. Regulation of hepatic bile acid transporters Ntcp and Bsep expression.
Biochem. Pharmacol. 74: 1665-1676 (2007).
*
-
Cheng X, Guerasimova A, Manke T, Rosenstiel P, Haas S, Warnatz HJ, Querfurth R, Nietfeld W, Vanhecke D, Lehrach H, Yaspo ML, Janitz M. Screening of human gene promoter activities using transfected-cell arrays.
Gene 450: 48-54 (2010).
-
Cheng X, Klaassen CD. Critical role of PPARalpha in perfluorooctanoic acid- and perfluorodecanoic acid-induced down-regulation of Oatp uptake transporters in mouse livers.
Toxicol. Sci. 106: 37-45 (2008).
*
-
Cheng Y, Ohlsson L, Duan RD. Psyllium and fat in diets differentially affect the activities and expressions of colonic sphingomyelinases and caspase in mice.
Br. J. Nutr. 91: 715-723 (2004).
*
-
Cheng Y, Ping J, Xu LM. Effects of curcumin on peroxisome proliferator-activated receptor gamma expression and nuclear translocation/redistribution in culture-activated rat hepatic stellate cells.
Chin. Med. J. (Engl.) 120: 794-801 (2007).
-
Cheng YH, Yin P, Xue Q, Yilmaz B, Dawson MI, Bulun SE. Retinoic acid regulates 17beta-hydroxysteroid dehydrogenase type 2 expression in endometrium: interaction of retinoic acid receptors with SP1/SP3 for estradiol metabolism.
J. Clin. Endocrinol. Metab. 93: 1915-1923 (2008).
*
-
Chentoufi AA, Binder NR, Berka N, Abunadi T, Polychronakos C. Advances in type I diabetes associated tolerance mechanisms.
Scand. J. Immunol. 68: 1-11 (2008).
*
-
Cheon CW, Kim DH, Kim DH, Cho YH, Kim JH. Effects of ciglitazone and troglitazone on the proliferation of human stomach cancer cells.
World J. Gastroenterol. 15: 310-320 (2009).
*
-
Cheon H, Rho YH, Choi SJ, Lee YH, Song GG, Sohn J, Won NH, Ji JD. Prostaglandin E2 augments IL-10 signaling and function.
J. Immunol. 177: 1092-1100 (2006).
*
-
Cheon JH, Kim JS, Kim JM, Kim N, Jung HC, Song IS. Plant sterol guggulsterone inhibits nuclear factor-kappaB signaling in intestinal epithelial cells by blocking IkappaB kinase and ameliorates acute murine colitis.
Inflamm. Bowel Dis. 12: 1152-1161 (2006).
*
-
Cheon Y, Nara TY, Band MR, Beever JE, Wallig MA, Nakamura MT. Induction of overlapping genes by fasting and a peroxisome proliferator in pigs: evidence of functional PPAR alpha in non-proliferating species.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 288: R1525-R1535 (2005).
*
-
Cherkaoui-Malki M, Meyer K, Cao WQ, Latruffe N, Yeldandi AV, Rao MS, Bradfield CA, Reddy JK. Identification of novel peroxisome proliferator-activated receptor alpha (PPARalpha) target genes in mouse liver using cDNA microarray analysis.
Gene Expr. 9: 291-304 (2001).
-
Chernajovsky Y, Gould DJ, Podhajcer OL. Gene therapy for autoimmune diseases: quo vadis?
Nat. Rev. Immunol. 4: 800-811 (2004).
*
-
Chernavsky AC, Paladino N, Rubio AE, De Biasio MB, Periolo N, Cuarterolo M, Goni J, Galoppo C, Canero-Velasco MC, Munoz AE, Fainboim H, Fainboim L. Simultaneous expression of Th1 cytokines and IL-4 confers severe characteristics to type I autoimmune hepatitis in children.
Hum. Immunol. 65: 683-691 (2004).
-
Cherrington NJ, Hartley DP, Li N, Johnson DR, Klaassen CD. Organ distribution of multidrug resistance proteins 1, 2, and 3 (Mrp1, 2, and 3) mRNA and hepatic induction of Mrp3 by constitutive androstane receptor activators in rats.
J. Pharmacol. Exp. Ther. 300: 97-104 (2002).
*
-
Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, Kranz DM. The impact of TCR-binding properties and antigen presentation format on T cell responsiveness.
J. Immunol. 183: 1166-1178 (2009).
-
Chessler AD, Ferreira LR, Chang TH, Fitzgerald KA, Burleigh BA. A novel IFN regulatory factor 3-dependent pathway activated by trypanosomes triggers IFN-beta in macrophages and fibroblasts.
J. Immunol. 181: 7917-7924 (2008).
*
-
Cheuk E, D'Souza C, Hu N, Liu Y, Lang H, Chamberlain JW. Human MHC class I transgenic mice deficient for H2 class I expression facilitate identification and characterization of new HLA class I-restricted viral T cell epitopes.
J. Immunol. 169: 5571-5580 (2002).
*
-
Cheung B, Yan J, Smith SA, Nguyen T, Lee M, Kavallaris M, Norris MD, Haber M, Marshall GM. Growth inhibitory retinoid effects after recruitment of retinoid X receptor beta to the retinoic acid receptor beta promoter.
Int. J. Cancer 105: 856-867 (2003).
*
-
Cheung C, Akiyama TE, Kudo G, Gonzalez FJ. Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1alpha)-deficient mice.
Biochem. Pharmacol. 66: 2011-2020 (2003).
*
-
Cheung C, Yu AM, Chen CS, Krausz KW, Byrd LG, Feigenbaum L, Edwards RJ, Waxman DJ, Gonzalez FJ. Growth hormone determines sexual dimorphism of hepatic cytochrome P450 3A4 expression in transgenic mice.
J. Pharmacol. Exp. Ther. 316: 1328-1334 (2006).
*
-
Cheung C, Yu AM, Ward JM, Akiyama TE, Feigenbaum L, Gonzalez FJ. The CYP2E1 humanized transgenic mouse: role of CYP2E1 acetaminophen hepatotoxicity.
Drug Metab. Dispos. 33: 449-457 (2005).
*
-
Cheung KP, Yang E, Goldrath AW. Memory-like CD8+ T cells generated during homeostatic proliferation defer to antigen-experienced memory cells.
J. Immunol. 183: 3364-3372 (2009).
-
Cheung O, Puri P, Eicken C, Contos MJ, Mirshahi F, Maher JW, Kellum JM, Min H, Luketic VA, Sanyal AJ. Nonalcoholic steatohepatitis is associated with altered hepatic microRNA expression.
Hepatology 48: 1810-1820 (2008).
*
-
Cheung PF, Wong CK, Ip WK, Lam CW. IL-25 regulates the expression of adhesion molecules on eosinophils: mechanism of eosinophilia in allergic inflammation.
Allergy 61: 878-885 (2006).
*
-
Cheung RS, Brooling JT, Johnson MM, Riehle KJ, Campbell JS, Fausto N. Interactions between MYC and transforming growth factor alpha alter the growth and tumorigenicity of liver progenitor cells.
Carcinogenesis 28: 2624-2631 (2007).
*
-
Cheung VG, Spielman RS. Data for Genetic Analysis Workshop (GAW) 15, Problem 1: genetics of gene expression variation in humans.
BMC Proc. 1 Suppl. 1: S2 (2007).
*
-
Cheung VG, Spielman RS, Ewens KG, Weber TM, Morley M, Burdick JT. Mapping determinants of human gene expression by regional and genome-wide association.
Nature 437: 1365-1369 (2005).
*
-
Cheunsuk S, Hsu T, Gershwin ME, Bowlus CL. Analysis of the IDDM candidate gene Prss16 in NOD and NON mice.
Dev. Immunol. 9: 183-186 (2002).
*
-
Cheunsuk S, Lian ZX, Yang GX, Gershwin ME, Gruen JR, Bowlus CL. Prss16 is not required for T-cell development.
Mol. Cell. Biol. 25: 789-796 (2005).
*
-
Chew CH, Chew GS, Najimudin N, Tengku-Muhammad TS. Interleukin-6 inhibits human peroxisome proliferator activated receptor alpha gene expression via CCAAT/enhancer-binding proteins in hepatocytes.
Int. J. Biochem. Cell Biol. 39: 1975-1986 (2007).
*
-
Chew V, Tow C, Teo M, Wong HL, Chan J, Gehring A, Loh M, Bolze A, Quek R, Lee VK, Lee KH, Abastado JP, Toh HC, Nardin A. Inflammatory tumor microenvironment is associated with superior survival in hepatocellular carcinoma patients.
J. Hepatol. Aug 3 [Epub ahead of print] (2009).
-
Chhikara M, Wang S, Kern SJ, Ferreyra GA, Barb JJ, Munson PJ, Danner RL. Carbon monoxide blocks lipopolysaccharide-induced gene expression by interfering with proximal TLR4 to NF-kappaB signal transduction in human monocytes.
PLoS One 4: e8139 (2009).
*
-
Chi CH, Liu IL, Lo WY, Liaw BS, Wang YS, Chi KH. Hepatocyte growth factor gene therapy prevents radiation-induced liver damage.
World J. Gastroenterol. 11: 1496-1502 (2005).
*
-
Chi Y, Hong Y, Zong H, Wang Y, Zou W, Yang J, Kong X, Yun X, Gu J. CDK11(p58) represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation.
Biochem. Biophys. Res. Commun. 386: 493-498 (2009).
*
-
Chia WT, Chen YW, Cheng LY, Lee HS, Chang DM, Sytwu HK. MMP-9 mRNA as a therapeutic marker in acute and chronic stages of arthritis induced by type II collagen antibody.
J. Formos. Med. Assoc. 107: 245-252 (2008).
-
Chianale J, Vollrath V, Wielandt AM, Amigo L, Rigotti A, Nervi F, Gonzalez S, Andrade L, Pizarro M, Accatino L. Fibrates induce mdr2 gene expression and biliary phospholipid secretion in the mouse.
Biochem. J. 314: 781-786 (1996).
*
-
Chiang JY. Bile acid regulation of gene expression: roles of nuclear hormone receptors.
Endocr. Rev. 23: 443-463 (2002).
*
-
Chiang JY, Kimmel R, Stroup D. Regulation of cholesterol 7alpha-hydroxylase gene (CYP7A1) transcription by the liver orphan receptor (LXRalpha).
Gene 262: 257-265 (2001).
*
-
Chiang JY, Li T, Song KH, Owsley E. Regulation of CYP7A1 by nuclear receptor signaling in human liver cells.
Falk Symposium 155. XIII FALK LIVER WEEK (Part I) XIX International Bile Acid Meeting. Bile Acids: Biological Actions and Clinical Relevance, October 6 - 7, 2006 Freiburg (Germany), p. 50 (2006). *
-
Chiang JYL, Li T, Jahan A. Mechanisms of bile acid inhibition of genes in bile acid synthesis.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 23. June 18-19 (2004). *
-
Chiba H, Sakai N, Murata M, Osanai M, Ninomiya T, Kojima T, Sawada N. The nuclear receptor hepatocyte nuclear factor 4alpha acts as a morphogen to induce the formation of microvilli.
J. Cell Biol. 175: 971-980 (2006).
*
-
Chiba K. A new orally active anti-rheumatic drug targets IL-15 and IL-17.
Nihon Rinsho Meneki Gakkai Kaishi 30: 375-382 (2007).
-
Chiba T, Kita K, Zheng YW, Yokosuka O, Saisho H, Iwama A, Nakauchi H, Taniguchi H. Side population purified from hepatocellular carcinoma cells harbors cancer stem cell-like properties.
Hepatology 44: 240-251 (2006).
*
-
Chiba T, Yokosuka O, Arai M, Tada M, Fukai K, Imazeki F, Kato M, Seki N, Saisho H. Identification of genes up-regulated by histone deacetylase inhibition with cDNA microarray and exploration of epigenetic alterations on hepatoma cells.
J. Hepatol. 41: 436-445 (2004).
*
-
Chiba T, Zheng YW, Kita K, Yokosuka O, Saisho H, Onodera M, Miyoshi H, Nakano M, Zen Y, Nakanuma Y, Nakauchi H, Iwama A, Taniguchi H. Enhanced self-renewal capability in hepatic stem/progenitor cells drives cancer initiation.
Gastroenterology 133: 937-950 (2007).
*
-
Chichelnitskiy E, Vegiopoulos A, Diaz MB, Ziegler A, Kleiman A, Rauch A, Tuckermann J, Herzig S. In vivo phosphoenolpyruvate carboxykinase promoter mapping identifies disrupted hormonal synergism as a target of inflammation during sepsis in mice.
Hepatology 50: 1963-1971 (2009).
-
Chien CC, Chen SH, Liu CC, Lee CL, Yang RN, Yang SH, Huang CJ. Correlation of K-ras codon 12 mutations in human feces and ages of patients with colorectal cancer (CRC).
Transl. Res. 149: 96-102 (2007).
*
-
Chien CW, Ho IC, Lee TC. Induction of neoplastic transformation by ectopic expression of human aldo-keto reductase 1C isoforms in NIH3T3 cells.
Carcinogenesis 30: 1813-1820 (2009).
*
-
Chignard N, Mergey M, Barbu V, Finzi L, Tiret E, Paul A, Housset C. VPAC1 expression is regulated by FXR agonists in the human gallbladder epithelium.
Hepatology 42: 549-557 (2005).
*
-
Chignard N, Mergey M, Veissiere D, Parc R, Capeau J, Poupon R, Paul A, Housset C. Bile acid transport and regulating functions in the human biliary epithelium.
Hepatology 33: 496-503 (2001).
*
-
Chignola F, Gaetani M, Rebane A, Org T, Mollica L, Zucchelli C, Spitaleri A, Mannella V, Peterson P, Musco G. The solution structure of the first PHD finger of autoimmune regulator in complex with non-modified histone H3 tail reveals the antagonistic role of H3R2 methylation.
Nucleic Acids Res. 37: 2951-2961 (2009).
*
-
Chikahisa S, Tominaga K, Kawai T, Kitaoka K, Oishi K, Ishida N, Rokutan K, Sei H. Bezafibrate, a PPARs agonist, decreases body temperature and enhances electroencephalogram delta-oscillation during sleep in mice.
Endocrinology 149: 5262-5271 (2008).
*
-
Chikamatsu K, Sakakura K, Matsuoka T, Endo S, Takahashi G, Matsuzaki Z, Masuyama K. Analysis of T-helper responses and FOXP3 gene expression in patients with Japanese cedar pollinosis.
Am. J. Rhinol. 22: 582-588 (2008).
-
Chikanza IC, Kozaci D, Chernajovsky Y. The molecular and cellular basis of corticosteroid resistance.
J. Endocrinol. 179: 301-310 (2003).
*
-
Childress PJ, Fletcher RL, Perumal NB. LymphTF-DB: a database of transcription factors involved in lymphocyte development.
Genes Immun. 8: 360-365 (2007).
*
-
Childs S, Carter F, Lynch CO, Sreenan JM, Lonergan P, Hennessy AA, Kenny DA. Embryo yield and quality following dietary supplementation of beef heifers with n-3 polyunsaturated fatty acids (PUFA).
Theriogenology 70: 992-1003 (2008).
-
Chilton PM, Fernandez-Botran R. Regulation of the expression of the soluble and membrane forms of the murine IL-4 receptor.
Cell. Immunol. 180: 104-115 (1997).
*
-
Chin D, Boyle GM, Theile DR, Parsons PG, Coman WB. The human genome and gene expression profiling.
J. Plast. Reconstr. Aesthet. Surg. 59: 902-911 (2006).
-
Chin JE, Soffir R, Noonan KE, Choi K, Roninson IB. Structure and expression of the human MDR (P-glycoprotein) gene family.
Mol. Cell Biol. 9: 3808-3820 (1989).
*
-
Chin RK, Lo JC, Kim O, Blink SE, Christiansen PA, Peterson P, Wang Y, Ware C, Fu YX. Lymphotoxin pathway directs thymic Aire expression.
Nat. Immunol. 4: 1121-11237 (2003).
*
-
Chinen J, Shearer WT. Advances in asthma, allergy and immunology series 2004: basic and clinical immunology.
J. Allergy Clin. Immunol. 114: 398-405 (2004).
*
-
Chinenov Y, Rogatsky I. Glucocorticoids and the innate immune system: crosstalk with the Toll-like receptor signaling network.
Mol. Cell. Endocrinol. 275: 30-42 (2007).
-
Chinese Human Liver Proteome Profiling Consortium. First insight into the human liver proteome from PROTEOME(SKY)-LIVER(Hu) 1.0, a publicly available database.
J. Proteome Res. Sep 3 [Epub ahead of print] (2009).
*
-
Chinetti G, Fruchart JC, Staels B. Transcriptional regulation of macrophage cholesterol trafficking by PPARalpha and LXR.
Biochem. Soc. Trans. 34: 1128-1131 (2006).
*
-
Chinetti G, Fruchart JC, Staels B. Peroxisome proliferator-activated receptors and inflammation: from basic science to clinical applications.
Int. J. Obes. Relat. Metab. Disord. 27 Suppl. 3: S41-S45 (2003).
-
Chinetti G, Zawadski C, Fruchart JC, Staels B. Expression of adiponectin receptors in human macrophages and regulation by agonists of the nuclear receptors PPARalpha, PPARgamma, and LXR.
Biochem. Biophys. Res. Commun. 314: 151-158 (2004).
*
-
Chinetti-Gbaguidi G, Rigamonti E, Helin L, Mutka AL, Lepore M, Fruchart JC, Clavey V, Ikonen E, Lestavel S, Staels B. Peroxisome proliferator-activated receptor-alpha controls cellular cholesterol trafficking in macrophages.
J. Lipid Res. 46: 2717-2725 (2005).
*
-
Ching GK, Hon KL, Ng PC, Leung TF. Filaggrin null mutations in childhood atopic dermatitis among the Chinese.
Int. J. Immunogenet. 36: 251-254 (2009).
*
-
Chinnery HR, Ruitenberg MJ, Plant GW, Pearlman E, Jung S, McMenamin PG. The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium.
Invest. Ophthalmol. Vis. Sci. 48: 1568-1574 (2007).
*
-
Chinoy H, Lamb JA, Ollier WE, Cooper RG. An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond.
Curr. Opin. Rheumatol. 21: 588-593 (2009).
-
Chintalgattu V, Harris GS, Akula SM, Katwa LC. PPAR-gamma agonists induce the expression of VEGF and its receptors in cultured cardiac myofibroblasts.
Cardiovasc. Res. 74: 140-150 (2007).
*
-
Chintharlapalli S, Papineni S, Jutooru I, McAlees A, Safe S. Structure-dependent activity of glycyrrhetinic acid derivatives as peroxisome proliferator-activated receptor gamma agonists in colon cancer cells.
Mol. Cancer Ther. 6: 1588-1598 (2007).
-
Chintharlapalli S, Papineni S, Safe S. 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes inhibit colon cancer cell and tumor growth through PPARgamma-dependent and PPARgamma-independent pathways.
Mol. Cancer Ther. 5: 1362-1370 (2006).
-
Chisaki I, Kobayashi M, Itagaki S, Hirano T, Iseki K. Liver X receptor regulates expression of MRP2 but not that of MDR1 and BCRP in the liver.
Biochim. Biophys. Acta 1788: 2396-2403 (2009).
*
-
Chistiakov DA. Interferon induced with helicase C domain 1 (IFIH1) and virus-induced autoimmunity: a review.
Viral Immunol. 23: 3-15 (2010).
-
Chistiakov DA, Savost'anov KV, Turakulov RI, Efremov IA, Demurov LM. Genetic analysis and functional evaluation of the C/T(-318) and A/G(-1661) polymorphisms of the CTLA-4 gene in patients affected with Graves' disease.
Clin. Immunol. 118: 233-242 (2006).
*
-
Chithalen JV, Luu L, Petkovich M, Jones G. HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A.
J. Lipid Res. 43: 1133-1142 (2002).
*
-
Chitnis T, Imitola J, Wang Y, Elyaman W, Chawla P, Sharuk M, Raddassi K, Bronson RT, Khoury SJ. Elevated neuronal expression of CD200 protects Wlds mice from inflammation-mediated neurodegeneration.
Am. J. Pathol. 170: 1695-1712 (2007).
*
-
Chiu IM, Chen A, Zheng Y, Kosaras B, Tsiftsoglou SA, Vartanian TK, Brown RH Jr, Carroll MC. T lymphocytes potentiate endogenous neuroprotective inflammation in a mouse model of ALS.
Proc. Natl. Acad. Sci. U.S.A. 105: 17913-17918 (2008).
*
-
Chiu MM, Ko YJ, Tsou AP, Chau GY, Chau YP. Analysis of NQO1 polymorphisms and p53 protein expression in patients with hepatocellular carcinoma.
Histol. Histopathol. 24: 1223-1232 (2009).
*
-
Chiu YG, Shao T, Feng C, Mensah KA, Thullen M, Schwarz EM, Ritchlin CT. CD16 (FcRgammaIII) as a potential marker of osteoclast precursors in psoriatic arthritis.
Arthritis Res. Ther. 12: R14 (2010).
*
-
Chizzolini C, Chicheportiche R, Alvarez M, de Rham C, Roux-Lombard P, Ferrari-Lacraz S, Dayer JM. Prostaglandin E2 (PGE2) synergistically with interleukin-23 (IL-23) favors human Th17 expansion.
Blood 112: 3696-3703 (2008).
*
-
Chizzolini C, Dayer JM, Miossec P. Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance?
Arthritis Res. Ther. 11: 246 (2009).
-
Chloupkova M, Pickert A, Lee JY, Souza S, Trinh YT, Connelly SM, Dumont ME, Dean M, Urbatsch IL. Expression of 25 human ABC transporters in the yeast Pichia pastoris and characterization of the purified ABCC3 ATPase activity.
Biochemistry 46: 7992-8003 (2007).
*
-
Chng WJ, Remstein ED, Fonseca R, Bergsagel PL, Vrana JA, Kurtin PJ, Dogan A. Gene expression profiling of pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma identifies new biological insights with potential diagnostic and therapeutic applications.
Blood 113: 635-645 (2009).
*
-
Cho BO, Jeong YW, Kim SH, Park K, Lee JH, Kweon GR, Park JC. Up-regulation of the BTG2 gene in TPA- or RA-treated HL-60 cell lines.
Oncol. Rep. 19: 633-637 (2008).
*
-
Cho CH, Parashurama N, Park EY, Suganuma K, Nahmias Y, Park J, Tilles AW, Berthiaume F, Yarmush ML. Homogeneous differentiation of hepatocyte-like cells from embryonic stem cells: applications for the treatment of liver failure.
FASEB J. 22: 898-909 (2008).
*
-
Cho HJ, Cho HJ, Kim HS. Osteopontin: a multifunctional protein at the crossroads of inflammation, atherosclerosis, and vascular calcification.
Curr. Atheroscler. Rep. 11: 206-213 (2009).
-
Cho HY, Reddy SP, Debiase A, Yamamoto M, Kleeberger SR. Gene expression profiling of NRF2-mediated protection against oxidative injury.
Free Radic. Biol. Med. 38: 325-343 (2005).
-
Cho J. Genetic advances in inflammatory bowel disease.
Curr. Treat. Options Gastroenterol. 9: 191-200 (2006).
-
Cho J. Update on inflammatory bowel disease genetics.
Curr. Gastroenterol. Rep. 2: 434-439 (2000).
-
Cho JH. Update on the genetics of inflammatory bowel disease.
Curr. Gastroenterol. Rep. 3: 458-463 (2001).
-
Cho JH, Abraham C. Inflammatory bowel disease genetics: Nod2.
Annu. Rev. Med. 58: 401-416 (2007).
*
-
Cho JH, Weaver CT. The genetics of inflammatory bowel disease.
Gastroenterology 133: 1327-1339 (2007).
*
-
Cho JJ, Joseph B, Sappal BS, Giri RK, Wang R, Ludlow JW, Furth ME, Susick R, Gupta S. Analysis of the functional integrity of cryopreserved human liver cells including xenografting in immunodeficient mice to address suitability for clinical applications.
Liver Int. 24: 361-370 (2004).
*
-
Cho JS, Kim YC, Morrison SL. Inhibitors of MyD88-dependent proinflammatory cytokine production identified utilizing a novel RNA interference screening approach.
PLoS One 4: e7029 (2009).
-
Cho JY, Matsubara T, Kang DW, Ahn SH, Krausz KW, Idle JR, Luecke H, Gonzalez FJ. Urinary metabolomics in Fxr-null mice reveals activated adaptive metabolic pathways upon bile acid challenge.
J. Lipid Res. Nov 9 [Epub ahead of print] (2009).
*
-
Cho KH, Caparon MG. tRNA modification by GidA/MnmE is necessary for Streptococcus pyogenes virulence: a new strategy to make live attenuated strains.
Infect. Immun. 76: 3176-3186 (2008).
*
-
Cho MC, Lee K, Paik SG, Yoon DY. Peroxisome proliferators-activated receptor (PPAR) modulators and metabolic disorders.
PPAR Res. 2008: 679137 (2008).
*
-
Cho MC, Lee S, Choi HS, Yang Y, Tae Hong J, Kim SJ, Yoon DY. Optimization of an enzyme-linked immunosorbent assay to screen ligand of peroxisome proliferator-activated receptor alpha.
Immunopharmacol. Immunotoxicol. 31: 459-467 (2009).
-
Cho MC, Yoon HE, Kang JW, Park SW, Yang Y, Hong JT, Song EY, Paik SG, Kim SH, Yoon DY. A simple method to screen ligands of peroxisome proliferator-activated receptor delta.
Eur. J. Pharm. Sci. 29: 355-360 (2006).
*
-
Cho ML, Ju JH, Kim HR, Oh HJ, Kang CM, Jhun JY, Lee SY, Park MK, Min JK, Park SH, Lee SH, Kim HY. Toll-like receptor 2 ligand mediates the upregulation of angiogenic factor, vascular endothelial growth factor and interleukin-8/CXCL8 in human rheumatoid synovial fibroblasts.
Immunol. Lett. 108: 121-128 (2007).
-
Cho NH, Seong SY. Apolipoproteins inhibit the innate immunity activated by necrotic cells or bacterial endotoxin.
Immunology 128: e479-e486 (2009).
*
-
Cho Y, Noshiro M, Choi M, Morita K, Kawamoto T, Fujimoto K, Kato Y, Makishima M. The basic helix-loop-helix proteins DEC1 and DEC2 function as corepressors of retinoid X receptors.
Mol. Pharmacol. 76: 1360-1369 (2009).
-
Cho-Rok J, Yoo J, Jang YJ, Kim S, Chu IS, Yeom YI, Choi JY, Im DS. Adenovirus-mediated transfer of siRNA against PTTG1 inhibits liver cancer cell growth in vitro and in vivo.
Hepatology 43: 1042-1052 (2006).
*
-
Choe SS, Choi AH, Lee JW, Kim KH, Chung JJ, Park J, Lee KM, Park KG, Lee IK, Kim JB. Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis.
Diabetes 56: 1534-1543 (2007).
*
-
Choi BM, Pae HO, Jeong YR, Kim YM, Chung HT. Critical role of heme oxygenase-1 in Foxp3-mediated immune suppression.
Biochem. Biophys. Res. Commun. 327: 1066-1071 (2005).
*
-
Choi CW, Chung YJ, Slape C, Aplan PD. A NUP98-HOXD13 fusion gene impairs differentiation of B and T lymphocytes and leads to expansion of thymocytes with partial TCRB gene rearrangement.
J. Immunol. 183: 6227-6235 (2009).
-
Choi D, Appukuttan B, Binek SJ, Planck SR, Stout JT, Rosenbaum JT, Smith JR. Prediction of cis-regulatory elements controlling genes differentially expressed by retinal and choroidal vascular endothelial cells.
J. Ocul. Biol. Dis. Infor. 1: 37-45 (2008).
-
Choi EW, Shin IS, Lee CW, Youn HY. The effect of gene therapy using CTLA4Ig/silica-nanoparticles on canine experimental autoimmune thyroiditis.
J. Gene Med. 10: 795-804 (2008).
*
-
Choi HK, Waxman DJ. Pulsatility of growth hormone (GH) signalling in liver cells: role of the JAK-STAT5b pathway in GH action.
Growth Horm. IGF Res. 10 Suppl. B: S1-S8 (2000).
-
Choi HK, Yang JW, Roh SH, Han CY, Kang KW. Induction of multidrug resistance associated protein 2 in tamoxifen-resistant breast cancer cells.
Endocr. Relat. Cancer 14: 293-303 (2007).
-
Choi HM, Oh DH, Bang JS, Yang HI, Yoo MC, Kim KS. Differential effect of IL-1beta and TNF-alpha on the production of IL-6, IL-8 and PGE(2) in fibroblast-like synoviocytes and THP-1 macrophages.
Rheumatol. Int. Aug 21 [Epub ahead of print] (2009).
*
-
Choi IK, Kim YH, Kim JS, Seo JH. PPAR-gamma ligand promotes the growth of APC-mutated HT-29 human colon cancer cells in vitro and in vivo.
Invest. New Drugs 26: 283-288 (2008).
-
Choi J, Ha KH, Byun MS, Min SY, Park MJ, Park HS, Oh HJ, Ju JH, Kim HY, Jue DM. Treatment with N-tosyl-L-phenylalanine chloromethyl ketone after the onset of collagen-induced arthritis reduces joint erosion and NF-kappaB activation.
Eur. J. Pharmacol. 595: 108-113 (2008).
-
Choi JK, Kim YJ. Intrinsic variability of gene expression encoded in nucleosome positioning sequences.
Nat. Genet. 41: 498-503 (2009).
*
-
Choi JS, Bae JY, Kim DS, Li J, Kim JL, Lee YJ, Kang YH. Dietary compound quercitrin dampens VEGF induction and PPARgamma activation in oxidized LDL-exposed murine macrophages: association with scavenger receptor CD36.
J. Agric. Food Chem. Nov 23 [Epub ahead of print] (2009).
*
-
Choi JW, Park CS, Hwang M, Nam HY, Chang HS, Park SG, Han BG, Kimm K, Kim HL, Oh B, Kim Y. A common intronic variant of CXCR3 is functionally associated with gene expression levels and the polymorphic immune cell responses to stimuli.
J. Allergy Clin. Immunol. 122: 1119-1126.e7 (2008).
*
-
Choi M, Inagaki T, Moschetta A, Mangelsdorf DJ, Kliewer S. Regulation of bile acid homeostasis by FXR and FGF15.
Falk Symposium 155. XIII FALK LIVER WEEK (Part I) XIX International Bile Acid Meeting. Bile Acids: Biological Actions and Clinical Relevance, October 6 - 7, 2006 Freiburg (Germany), p. 53 (2006). *
-
Choi M, Rolle S, Rane M, Haller H, Luft FC, Kettritz R. Extracellular signal-regulated kinase inhibition by statins inhibits neutrophil activation by ANCA.
Kidney Int. 63: 96-106 (2003).
*
-
Choi MK, Song IS. Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences.
Drug Metab. Pharmacokinet. 23: 243-253 (2008).
-
Choi SM, Cho HJ, Cho H, Kim KH, Kim JB, Park H. Stra13/DEC1 and DEC2 inhibit sterol regulatory element binding protein-1c in a hypoxia-inducible factor-dependent mechanism.
Nucleic Acids Res. 36: 6372-6385 (2008).
*
-
Choi SS, Sicklick JK, Ma Q, Yang L, Huang J, Qi Y, Chen W, Li YX, Goldschmidt-Clermont PJ, Diehl AM. Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.
Hepatology 44: 1267-1277 (2006).
*
-
Choi SY, Chung JH, Kim DH, Chung SW, Kim JY, Yu BP, Chung HY. Peroxisome proliferator-activated receptor gamma agonist action of 3-methyl-1,2-cyclopentanedione.
Biochim. Biophys. Acta 1770: 1612-1619 (2007).
*
-
Chong BF, Wilson AJ, Gibson HM, Hafner MS, Luo Y, Hedgcock CJ, Wong HK. Immune function abnormalities in peripheral blood mononuclear cell cytokine expression differentiates stages of cutaneous T-cell lymphoma/mycosis fungoides.
Clin. Cancer Res. 14: 646-653 (2008).
*
-
Chong WP, Ip WK, Wong WH, Lau CS, Chan TM, Lau YL. Association of interleukin-10 promoter polymorphisms with systemic lupus erythematosus.
Genes Immun. 5: 484-492 (2004).
*
-
Chopra AR, Louet JF, Saha P, An J, Demayo F, Xu J, York B, Karpen S, Finegold M, Moore D, Chan L, Newgard CB, O'Malley BW. Absence of the SRC-2 coactivator results in a glycogenopathy resembling Von Gierke's disease.
Science 322: 1395-1399 (2008).
*
-
Chopra P, Gulwani H. Pathology and pathogenesis of rheumatic heart disease.
Indian J. Pathol. Microbiol. 50: 685-697 (2007).
-
Chorny A, Gonzalez-Rey E, Delgado M. Regulation of dendritic cell differentiation by vasoactive intestinal peptide: therapeutic applications on autoimmunity and transplantation.
Ann. N. Y. Acad. Sci. 1088: 187-194 (2006).
*
-
Chou FC, Sytwu HK. Overexpression of thioredoxin in islets transduced by a lentiviral vector prolongs graft survival in autoimmune diabetic NOD mice.
J. Biomed. Sci. 16: 71 (2009).
*
-
Chou WL, Chuang LM, Khoo KH, Wang AH, Lawson JA, Fitzgerald GA, Chang ZF. Identification of a novel prostaglandin reductase reveals the involvement of prostaglandin E2 catabolism in regulation of PPARgamma activation.
J. Biol. Chem. 282: 18162-18172 (2007).
*
-
Chou YC, Prakash E, Huang CF, Lien TW, Chen X, Su IJ, Chao YS, Hsieh HP, Hsu JT. Bioassay-guided purification and identification of PPARalpha/gamma agonists from Chlorella sorokiniana.
Phytother. Res. 22: 605-613 (2008).
-
Choubey D, Deka R, Ho SM. Interferon-inducible IFI16 protein in human cancers and autoimmune diseases.
Front. Biosci. 13: 598-608 (2008).
-
Choubey D, Panchanathan R. Interferon-inducible Ifi200-family genes in systemic lupus erythematosus.
Immunol. Lett. 119: 32-41 (2008).
-
Choudhari SR, Khan MA, Harris G, Picker D, Jacob GS, Block T, Shailubhai K. Deactivation of Akt and STAT3 signaling promotes apoptosis, inhibits proliferation, and enhances the sensitivity of hepatocellular carcinoma cells to an anticancer agent, Atiprimod.
Mol. Cancer Ther. 6: 112-121 (2007).
-
Choudhary S, Lu M, Cui R, Brasier AR. Involvement of a novel Rac/RhoA guanosine triphosphatase-nuclear factor-kappaB inducing kinase signaling pathway mediating angiotensin II-induced RelA transactivation.
Mol. Endocrinol. 21: 2203-2217 (2007).
*
-
Choudhuri S, Klaassen CD. Structure, function, expression, genomic organization, and single nucleotide polymorphisms of human ABCB1 (MDR1), ABCC (MRP), and ABCG2 (BCRP) efflux transporters.
Int. J. Toxicol. 25: 231-259 (2006).
*
-
Choudhury K, McQuillin A, Puri V, Pimm J, Datta S, Thirumalai S, Krasucki R, Lawrence J, Bass NJ, Quested D, Crombie C, Fraser G, Walker N, Nadeem H, Johnson S, Curtis D, St Clair D, Gurling HM. A genetic association study of chromosome 11q22-24 in two different samples implicates the FXYD6 gene, encoding phosphohippolin, in susceptibility to schizophrenia.
Am. J. Hum. Genet. 80: 664-672 (2007).
*
-
Choukem SP, Boudou P, Sobngwi E, Villette JM, Ibrahim F, Moulin P, Hadjadj S, Eberle D, Foufelle F, Vexiau P, Gautier JF. The polymorphism Arg585Gln in the gene of the sterol regulatory element binding protein-1 (SREBP-1) is not a determinant of ketosis prone type 2 diabetes (KPD) in Africans.
Diabetes Metab. 35: 20-24 (2009).
-
Choumerianou DM, Dimitriou H, Perdikogianni C, Martimianaki G, Riminucci M, Kalmanti M. Study of oncogenic transformation in ex vivo expanded mesenchymal cells, from paediatric bone marrow.
Cell Prolif. 41: 909-922 (2008).
*
-
Chow A, Zhou W, Jacobson R. Regulation of AE2 Cl-/HCO3- exchanger during intestinal development.
Am. J. Physiol. 271: G330-G337 (1996).
-
Chow EC, Maeng HJ, Liu S, Khan AA, Groothuis GM, Pang KS. 1alpha,25-Dihydroxyvitamin D3 triggered vitamin D receptor and farnesoid X receptor-like effects in rat intestine and liver in vivo.
Biopharm. Drug Dispos. 30: 457-475 (2009).
*
-
Chow EK, Castrillo A, Shahangian A, Pei L, O'Connell RM, Modlin RL, Tontonoz P, Cheng G. A role for IRF3-dependent RXRalpha repression in hepatotoxicity associated with viral infections.
J. Exp. Med. 203: 2589-2602 (2006).
*
-
Chow WL, Lee YK. Free fucose is a danger signal to human intestinal epithelial cells.
Br. J. Nutr. 99: 449-454 (2008).
*
-
Chowanadisai W, Bauerly KA, Tchaparian E, Wong A, Cortopassi GA, Rucker RB. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through CREB phosphorylation and increased PGC-1alpha expression.
J. Biol. Chem. 285: 142-152 (2010).
*
-
Chowdhury SR, King DE, Willing BP, Band MR, Beever JE, Lane AB, Loor JJ, Marini JC, Rund LA, Schook LB, Van Kessel AG, Gaskins HR. Transcriptome profiling of the small intestinal epithelium in germfree versus conventional piglets.
BMC Genomics 8: 215 (2007).
*
-
Choy E, Yelensky R, Bonakdar S, Plenge RM, Saxena R, De Jager PL, Shaw SY, Wolfish CS, Slavik JM, Cotsapas C, Rivas M, Dermitzakis ET, Cahir-McFarland E, Kieff E, Hafler D, Daly MJ, Altshuler D. Genetic analysis of human traits in vitro: drug response and gene expression in lymphoblastoid cell lines.
PLoS Genet. 4: e1000287 (2008).
*
-
Christ AD, Stevens AC, Koeppen H, Walsh S, Omata F, Devergne O, Birkenbach M, Blumberg RS. An interleukin 12-related cytokine is up-regulated in ulcerative colitis but not in Crohn's disease.
Gastroenterology 115: 307-313 (1998).
*
-
Christensen SR, Shupe J, Nickerson K, Kashgarian M, Flavell RA, Shlomchik MJ. Toll-like receptor 7 and TLR9 dictate autoantibody specificity and have opposing inflammatory and regulatory roles in a murine model of lupus.
Immunity 25: 417-428 (2006).
*
-
Christensen T. Association of human endogenous retroviruses with multiple sclerosis and possible interactions with herpes viruses.
Rev. Med. Virol. 15: 179-211 (2005).
*
-
Christensen T, Moller-Larsen A. Human endogenous retroviruses and disease?
Ugeskr. Laeger. 165: 556-561 (2003).
-
Christenson LK, McAllister JM, Martin KO, Javitt NB, Osborne TF, Strauss JF 3rd. Oxysterol regulation of steroidogenic acute regulatory protein gene expression. Structural specificity and transcriptional and posttranscriptional actions.
J. Biol. Chem. 273: 30729-30735 (1998).
*
-
Christensson M, Pettersson E, Sundqvist KG, Christensson B. T cell activation in patients with ANCA-associated vasculitis: inefficient immune suppression by therapy.
Clin. Nephrol. 54: 435-442 (2000).
-
Christians U, Schmitz V, Haschke M. Functional interactions between P-glycoprotein and CYP3A in drug metabolism.
Expert Opin. Drug Metab. Toxicol. 1: 641-654 (2005).
-
Christianson JL, Nicoloro S, Straubhaar J, Czech MP. Stearoyl CoA desaturase 2 is required for PPARgamma expression and adipogenesis in cultured 3T3-L1 cells.
J. Biol. Chem. 283: 2906-2916 (2008).
*
-
Christophi GP, Panos M, Hudson CA, Christophi RL, Gruber RC, Mersich AT, Blystone SD, Jubelt B, Massa PT. Macrophages of multiple sclerosis patients display deficient SHP-1 expression and enhanced inflammatory phenotype.
Lab. Invest. 89: 742-759 (2009).
*
-
Chromik AM, Muller AM, Albrecht M, Rottmann S, Otte JM, Herdegen T, Uhl W, Mittelkotter U. Oral administration of taurolidine ameliorates chronic DSS colitis in mice.
J. Invest. Surg. 20: 273-282 (2007).
*
-
Chu AS, Friedman JR. A role for microRNA in cystic liver and kidney diseases.
J. Clin. Invest. 118: 3585-3587 (2008).
*
-
Chu CS, Trapnell BC, Curristin SM, Cutting GR, Crystal RG. Extensive posttranscriptional deletion of the coding sequences for part of nucleotide-binding fold 1 in respiratory epithelial mRNA transcripts of the cystic fibrosis transmembrane conductance regulator gene is not associated with the clinical …
J. Clin. Invest. 90: 785-790 (1992).
*
-
Chu EC, Chai J, Ahluwalia A, Tarnawski AS. Mesalazine downregulates c-Myc in human colon cancer cells. A key to its chemopreventive action?
Aliment. Pharmacol. Ther. 25: 1443-1449 (2007).
*
-
Chu JH, Weiss ST, Carey VJ, Raby BA. A graphical model approach for inferring large-scale networks integrating gene expression and genetic polymorphism.
BMC Syst. Biol. 3: 55 (2009).
*
-
Chu K, Miyazaki M, Man WC, Ntambi JM. Stearoyl-coenzyme A desaturase 1 deficiency protects against hypertriglyceridemia and increases plasma high-density lipoprotein cholesterol induced by liver X receptor activation.
Mol. Cell. Biol. 26: 6786-6798 (2006).
*
-
Chu R, Lim H, Brumfield L, Liu H, Herring C, Ulintz P, Reddy JK, Davison M. Protein profiling of mouse livers with peroxisome proliferator-activated receptor alpha activation.
Mol. Cell. Biol. 24: 6288-6297 (2004).
*
-
Chu WC, Hong WF, Huang MC, Chen FY, Lin SC, Liao PJ, Su JG. 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway.
Chem. Res. Toxicol. 22: 1938-1947 (2009).
*
-
Chua AC, Olynyk JK, Leedman PL, Trinder D. Nontransferrin-bound iron uptake by hepatocytes is increased in the Hfe knockout mouse model of hereditary hemochromatosis.
Blood 104: 1519-1525 (2004).
*
-
Chuang CC, Yang RS, Tsai KS, Ho FM, Liu SH. Hyperglycemia enhances adipogenic induction of lipid accumulation: involvement of extracellular signal-regulated protein kinase 1/2, phosphoinositide 3-kinase/Akt and peroxisome proliferator-activated receptor-gamma (PPARgamma) signaling.
Endocrinology 148: 4267-4275 (2007).
*
-
Chuang HC, Wang JM, Hsieh WC, Chang Y, Su IJ. Up-regulation of activating transcription factor-5 suppresses SAP expression to activate T cells in hemophagocytic syndrome associated with Epstein-Barr virus infection and immune disorders.
Am. J. Pathol. 173: 1397-1405 (2008).
*
-
Chuang SS, Chang ST, Chuang WY, Huang WT, Hsieh PP, Tsou MH, Liao YL, Lin SH, Hsieh YC, Lu CL, Sheu MJ, Liu H. NK-cell lineage predicts poor survival in primary intestinal NK-cell and T-cell lymphomas.
Am. J. Surg. Pathol. 33: 1230-1240 (2009).
-
Chuang WY, Strobel P, Belharazem D, Rieckmann P, Toyka KV, Nix W, Schalke B, Gold R, Kiefer R, Klinker E, Opitz A, Inoue M, Kuo TT, Muller-Hermelink HK, Marx A. The PTPN22(gain-of-function)+1858T(+) genotypes correlate with low IL-2 expression in thymomas and predispose to myasthenia gravis.
Genes Immun. 10: 667-672 (2009).
-
Chuang YH, Lian ZX, Tsuneyama K, Chiang BL, Ansari AA, Coppel RL, Eric Gershwin M. Increased killing activity and decreased cytokine production in NK cells in patients with primary biliary cirrhosis.
J. Autoimmun. 26: 232-240 (2006).
-
Chui MH, Papanikolaou Y, Fontaine-Bisson B, Turcotte J, Wolever TM, El-Sohemy A, Chiasson JL, Rabasa-Lhoret R, Maheux P, Ryan E, Greenwood CE. The TNF-alpha-238A single-nucleotide polymorphism protects against memory decline in older adults with type 2 diabetes.
Behav. Neurosci. 121: 619-624 (2007).
-
Chuma M, Sakamoto M, Yasuda J, Fujii G, Nakanishi K, Tsuchiya A, Ohta T, Asaka M, Hirohashi S. Overexpression of cortactin is involved in motility and metastasis of hepatocellular carcinoma.
J. Hepatol. 41: 629-636 (2004).
*
-
Chun KS, Surh YJ. Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention.
Biochem. Pharmacol. 68: 1089-1100 (2004).
*
-
Chung C, Doll JA, Stellmach VM, Gonzales J, Surapureddi S, Cornwell M, Reddy JK, Crawford SE. Pigment epithelium-derived factor is an angiogenesis and lipid regulator that activates peroxisome proliferator-activated receptor alpha.
Adv. Exp. Med. Biol. 617: 591-597 (2008).
-
Chung DD, Honda K, Cafuir L, McDuffie M, Wotton D. The Runx3 distal transcript encodes an additional transcriptional activation domain.
FEBS J. 274: 3429-3439 (2007).
*
-
Chung EY, Kim SJ, Ma XJ. Regulation of cytokine production during phagocytosis of apoptotic cells.
Cell Res. 16: 154-161 (2006).
*
-
Chung EY, Liu J, Zhang Y, Ma X. Differential expression in lupus-associated IL-10 promoter single-nucleotide polymorphisms is mediated by poly(ADP-ribose) polymerase-1.
Genes Immun. 8: 577-589 (2007).
*
-
Chung J, Koyama T, Ohsawa M, Shibamiya A, Hoshi A, Hirosawa S. 1,25(OH)(2)D(3) blocks TNF-induced monocytic tissue factor expression by inhibition of transcription factors AP-1 and NF-kappaB.
Lab. Invest. 87: 540-547 (2007).
*
-
Chung JS, Yudate T, Tomihari M, Akiyoshi H, Cruz PD Jr, Ariizumi K. Binding of DC-HIL to dermatophytic fungi induces tyrosine phosphorylation and potentiates antigen presenting cell function.
J. Immunol. 183: 5190-5198 (2009).
-
Chung KY, Park JJ, Kim YS. The role of high-mobility group box-1 in renal ischemia and reperfusion injury and the effect of ethyl pyruvate.
Transplant. Proc. 40: 2136-2138 (2008).
*
-
Chung L, Fiorentino DF, Benbarak MJ, Adler AS, Mariano MM, Paniagua RT, Milano A, Connolly MK, Ratiner BD, Wiskocil RL, Whitfield ML, Chang HY, Robinson WH. Molecular framework for response to imatinib mesylate in systemic sclerosis.
Arthritis Rheum. 60: 584-591 (2009).
*
-
Chung Moh M, Hoon Lee L, Shen S. Cloning and characterization of hepaCAM, a novel Ig-like cell adhesion molecule suppressed in human hepatocellular carcinoma.
J. Hepatol. 42: 833-841 (2005).
*
-
Chung S, Brown JM, Provo JN, Hopkins R, McIntosh MK. Conjugated linoleic acid promotes human adipocyte insulin resistance through NFkappaB-dependent cytokine production.
J. Biol. Chem. 280: 38445-38456 (2005).
*
-
Chung S, Lapoint K, Martinez K, Kennedy A, Boysen Sandberg M, McIntosh MK. Preadipocytes mediate lipopolysaccharide-induced inflammation and insulin resistance in primary cultures of newly differentiated human adipocytes.
Endocrinology 147: 5340-5351 (2006).
*
-
Chung SK, Lee MG, Ryu BK, Lee JH, Han J, Byun DS, Chae KS, Lee KY, Jang JY, Kim HJ, Chi SG. Frequent alteration of XAF1 in human colorectal cancers: implication for tumor cell resistance to apoptotic stresses.
Gastroenterology 132: 2459-2477 (2007).
*
-
Chung SS, Choi C, Wang X, Hallock L, Wolgemuth DJ. Aberrant distribution of junctional complex components in retinoic acid receptor alpha-deficient mice.
Microsc. Res. Tech. Nov 23 [Epub ahead of print] (2009).
-
Chung SS, Choi HH, Cho YM, Lee HK, Park KS. Sp1 mediates repression of the resistin gene by PPARgamma agonists in 3T3-L1 adipocytes.
Biochem. Biophys. Res. Commun. 348: 253-258 (2006).
*
-
Chung SS, Kim M, Youn BS, Lee NS, Park JW, Lee IK, Lee YS, Kim JB, Cho YM, Lee HK, Park KS. Glutathione peroxidase 3 mediates the antioxidant effect of peroxisome proliferator-activated receptor gamma in human skeletal muscle cells.
Mol. Cell. Biol. 29: 20-30 (2009).
*
-
Chung SW, Kang BY, Kim TS. Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor.
Mol. Pharmacol. 64: 1169-1179 (2003).
*
-
Chung TW, Moon SK, Chang YC, Ko JH, Lee YC, Cho G, Kim SH, Kim JG, Kim CH. Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanism.
FASEB J. 18: 1670-1681 (2004).
*
-
Chung WJ, Sontheimer H. Sulfasalazine inhibits the growth of primary brain tumors independent of nuclear factor-kappaB.
J. Neurochem. 110: 182-193 (2009).
-
Chung Y, Dong C. Don’t leave home without it: the IL-23 visa to TH-17 cells.
Nat. Immunol. 10: 236-238 (2009).
*
-
Chuu CP, Chen RY, Hiipakka RA, Kokontis JM, Warner KV, Xiang J, Liao S. The liver X receptor agonist T0901317 acts as androgen receptor antagonist in human prostate cancer cells.
Biochem. Biophys. Res. Commun. 357: 341-346 (2007).
*
-
Chuu CP, Hiipakka RA, Kokontis JM, Fukuchi J, Chen RY, Liao S. Inhibition of tumor growth and progression of LNCaP prostate cancer cells in athymic mice by androgen and liver X receptor agonist.
Cancer Res. 66: 6482-6486 (2006).
*
-
Ciana P, Biserni A, Tatangelo L, Tiveron C, Sciarroni AF, Ottobrini L, Maggi A. A novel PPRE-luciferase reporter mouse reveals gender specificity of peroxisome proliferators activated receptor activity in liver.
Mol. Endocrinol. 21: 388-400 (2007).
*
-
Cianfarani F, Baldini E, Cavalli A, Marchioni E, Lembo L, Teson M, Persechino S, Zambruno G, Ulisse S, Odorisio T, D'Armiento M. TSH receptor and thyroid-specific gene expression in human skin.
J. Invest. Dermatol. 130: 93-101 (2010).
*
-
Cianferotti L, Demay MB. VDR-mediated inhibition of DKK1 and SFRP2 suppresses adipogenic differentiation of murine bone marrow stromal cells.
J. Cell. Biochem. 101: 80-88 (2007).
*
-
Ciarapica R, Annibali D, Raimondi L, Savino M, Nasi S, Rota R. Targeting Id protein interactions by an engineered HLH domain induces human neuroblastoma cell differentiation.
Oncogene 28: 1881-1891 (2009).
*
-
Ciarimboli G, Schlatter E. Regulation of organic cation transport.
Pflugers Arch. 449: 423-441 (2005).
*
-
Ciccia F, Bombardieri M, Principato A, Giardina A, Tripodo C, Porcasi R, Peralta S, Franco V, Giardina E, Craxi A, Pitzalis C, Triolo G. Overexpression of interleukin-23, but not interleukin-17, as an immunologic signature of subclinical intestinal inflammation in ankylosing spondylitis.
Arthritis Rheum. 60: 955-965 (2009).
*
-
Ciccocioppo R, Ricci G, Rovati B, Pesce I, Mazzocchi S, Piancatelli D, Cagnoni A, Millimaggi D, Danova M, Corazza GR. Reduced number and function of peripheral dendritic cells in coeliac disease.
Clin. Exp. Immunol. 140: 487-496 (2007).
*
-
Cicin-Sain L, Messaoudi I, Park B, Currier N, Planer S, Fischer M, Tackitt S, Nikolich-Zugich D, Legasse A, Axthelm MK, Picker LJ, Mori M, Nikolich-Zugich J. Dramatic increase in naive T cell turnover is linked to loss of naive T cells from old primates.
Proc. Natl. Acad. Sci. U.S.A. 104: 19960-19965 (2007).
*
-
Ciecierski R, Wisniewski M, Paczek L. Liver regeneration.
Pol. Merkuriusz. Lek. 18: 473-477 (2005).
-
Cigana C, Curcuru L, Leone MR, Ierano T, Lore NI, Bianconi I, Silipo A, Cozzolino F, Lanzetta R, Molinaro A, Bernardini ML, Bragonzi A. Pseudomonas aeruginosa exploits lipid A and muropeptides modification as a strategy to lower innate immunity during cystic fibrosis lung infection.
PLoS One 4: e8439 (2009).
*
-
Cigana C, Nicolis E, Pasetto M, Assael BM, Melotti P. Effects of azithromycin on the expression of ATP binding cassette transporters in epithelial cells from the airways of cystic fibrosis patients.
J. Chemother. 19: 643-649 (2007).
-
Cimini A, Cristiano L, Benedetti E, D'Angelo B, Ceru MP. PPARs expression in adult mouse neural stem cells: modulation of PPARs during astroglial differentiaton of NSC.
PPAR Res. 2007: 48242 (2007).
*
-
Cintra DE, Pauli JR, Araujo EP, Moraes JC, de Souza CT, Milanski M, Morari J, Gambero A, Saad MJ, Velloso LA. Interleukin-10 is a protective factor against diet-induced insulin resistance in liver.
J. Hepatol. 48: 628-637 (2008).
*
-
Cippitelli M, Ye J, Viggiano V, Sica A, Ghosh P, Gulino A, Santoni A, Young HA. Retinoic acid-induced transcriptional modulation of the human interferon-gamma promoter.
J. Biol. Chem. 271: 26783-26793 (1996).
*
-
Cipriano C, Caruso C, Lio D, Giacconi R, Malavolta M, Muti E, Gasparini N, Franceschi C, Mocchegiani E. The -308G/A polymorphism of TNF-alpha influences immunological parameters in old subjects affected by infectious diseases.
Int. J. Immunogenet. 32: 13-18 (2005).
*
-
Circosta P, Granziero L, Follenzi A, Vigna E, Stella S, Vallario A, Elia AR, Gammaitoni L, Vitaggio K, Orso F, Geuna M, Sangiolo D, Todorovic M, Giachino C, Cignetti A. TCR gene transfer with lentiviral vectors allows efficient redirection of tumor specificity in naive and memory T-cells without prior stimulation of endogenous TCR.
Hum. Gene Ther. 20: 1576-1588 (2009).
-
Cirillo N, Prime SS. Desmosomal interactome in keratinocytes: a systems biology approach leading to an understanding of the pathogenesis of skin disease.
Cell. Mol. Life Sci. 66: 3517-3533 (2009).
*
-
Citi S, Paschoud S, Pulimeno P, Timolati F, De Robertis F, Jond L, Guillemot L. The tight junction protein cingulin regulates gene expression and RhoA signaling.
Ann. N. Y. Acad. Sci. 1165: 88-98 (2009).
*
-
Clabby ML, Robison TA, Quigley HF, Wilson DB, Kelly DP. Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2.
J. Biol. Chem. 278: 5760-5767 (2003).
*
-
Clancy RM, Zheng P, O'Mahony M, Izmirly P, Zavadil J, Gardner L, Buyon JP. Role of hypoxia and cAMP in the transdifferentiation of human fetal cardiac fibroblasts: implications for progression to scarring in autoimmune-associated congenital heart block.
Arthritis Rheum. 56: 4120-4131 (2007).
*
-
Clapp DW. Somatic gene therapy into hematopoietic cells. Current status and future implications.
Clin. Perinatol. 20: 155-168 (1993).
-
Clapp DW, Dumenco LL, Hatzoglou M, Gerson SL. Fetal liver hematopoietic stem cells as a target for in utero retroviral gene transfer.
Blood 78: 1132-1139 (1991).
*
-
Clapp DW, Freie B, Srour E, Yoder MC, Fortney K, Gerson SL. Myeloproliferative sarcoma virus directed expression of beta-galactosidase following retroviral transduction of murine hematopoietic cells.
Exp. Hematol. 23: 630-638 (1995).
-
Clapp DW, Williams DA. The use of umbilical cord blood as a cellular source for correction of genetic diseases affecting the hematopoietic system.
Stem Cells 13: 613-621 (1995).
-
Clapper ML, Szarka CE. Glutathione S-transferases - biomarkers of cancer risk and chemopreventive response.
Chem. Biol. Interact. 111-112: 377-388 (1998).
-
Claret L, Miquel S, Vieille N, Ryjenkov DA, Gomelsky M, Darfeuille Michaud A. The flagellar sigma factor Flia regulates adhesion and invasion of Crohn's disease-associated Escherichia coli via a c-di-GMP-dependent pathway.
J. Biol. Chem. 282: 33275-33283 (2007).
*
-
Clarizia AD, Bastos-Rodrigues L, Pena HB, Anacleto C, Rossi B, Soares FA, Lopes A, Rocha JC, Caballero O, Camargo A, Simpson AJ, Pena SD. Relationship of the methylenetetrahydrofolate reductase C677T polymorphism with microsatellite instability and promoter hypermethylation in sporadic colorectal cancer.
Genet. Mol. Res. 5: 315-322 (2006).
*
-
Clark AR. Anti-inflammatory functions of glucocorticoid-induced genes.
Mol. Cell. Endocrinol. 275: 79-97 (2007).
*
-
Clark AR, Martins JR, Tchen CR. Role of dual specificity phosphatases in biological responses to glucocorticoids.
J. Biol. Chem. 283: 25765-25769 (2008).
*
-
Clark IM, Swingler TE, Young DA. Acetylation in the regulation of metalloproteinase and tissue inhibitor of metalloproteinases gene expression.
Front. Biosci. 12: 528-535 (2007).
-
Clark PR, Pober JS, Kluger MS. Knockdown of TNFR1 by the sense strand of an ICAM-1 siRNA: dissection of an off-target effect.
Nucleic Acids Res. 36: 1081-1097 (2008).
*
-
Clark RB, Bishop-Bailey D, Estrada-Hernandez T, Hla T, Puddington L, Padula SJ. The nuclear receptor PPAR gamma and immunoregulation: PPAR gamma mediates inhibition of helper T cell responses.
J. Immunol. 164: 1364-1371 (2000).
*
-
Clarke DL, Sutcliffe A, Deacon K, Bradbury D, Corbett L, Knox AJ. PKCbetaII augments NF-kappaB-dependent transcription at the CCL11 promoter via p300/CBP-associated factor recruitment and histone H4 acetylation.
J. Immunol. 181: 3503-3514 (2008).
*
-
Clarke E, Rahman N, Page N, Rolph MS, Stewart GJ, Jones GJ. Functional characterization of the atopy-associated gene PHF11.
J. Allergy Clin. Immunol. 121: 1148-1154.e3 (2008).
*
-
Clarke SD. Nonalcoholic steatosis and steatohepatitis. I. Molecular mechanism for polyunsaturated fatty acid regulation of gene transcription.
Am. J. Physiol. Gastrointest. Liver Physiol. 281: G865-G869 (2001).
*
-
Clarke SD. The multi-dimensional regulation of gene expression by fatty acids: polyunsaturated fats as nutrient sensors.
Curr. Opin. Lipidol. 15: 13-18 (2004).
-
Clarke SD, Gasperikova D, Nelson C, Lapillonne A, Heird WC. Fatty acid regulation of gene expression: a genomic explanation for the benefits of the Mediterranean diet.
Ann. N. Y. Acad. Sci. 967: 283-298 (2002).
*
-
Clarke SD, Jump D. Polyunsaturated fatty acids regulate lipogenic and peroxisomal gene expression by independent mechanisms.
Prostaglandins Leukot. Essent. Fatty Acids 57: 65-69 (1997).
-
Clarke SD, Jump DB. Polyunsaturated fatty acid regulation of hepatic gene transcription.
Lipids 31: S7-S11 (1996).
-
Clarke SD, Thuillier P, Baillie RA, Sha X. Peroxisome proliferator-activated receptors: a family of lipid-activated transcription factors.
Am. J. Clin. Nutr. 70: 566-571 (1999).
*
-
Classen S, Zander T, Eggle D, Chemnitz JM, Brors B, Buchmann I, Popov A, Beyer M, Eils R, Debey S, Schultze JL. Human resting CD4(+) T cells are constitutively inhibited by TGFbeta under steady-state conditions.
J. Immunol. 178: 6931-6940 (2007).
*
-
Claudel T, Inoue Y, Barbier O, Duran-Sandoval D, Kosykh V, Fruchart J, Fruchart JC, Gonzalez FJ, Staels B. Farnesoid X receptor agonists suppress hepatic apolipoprotein CIII expression.
Gastroenterology 125: 544-555 (2003).
*
-
Claudino M, Garlet TP, Cardoso CR, de Assis GF, Taga R, Cunha FQ, Silva JS, Garlet GP. Down-regulation of expression of osteoblast and osteocyte markers in periodontal tissues associated with the spontaneous alveolar bone loss of interleukin-10 knockout mice.
Eur. J. Oral Sci. 118: 19-28 (2010).
-
Clavel G, Valvason C, Yamaoka K, Lemeiter D, Laroche L, Boissier MC, Bessis N. Relationship between angiogenesis and inflammation in experimental arthritis.
Eur. Cytokine Netw. 17: 202-210 (2006).
-
Clay BS, Shilling RA, Bandukwala HS, Moore TV, Cannon JL, Welcher AA, Weinstock JV, Sperling AI. Inducible costimulator expression regulates the magnitude of Th2-mediated airway inflammation by regulating the number of Th2 cells.
PLoS One 4: e7525 (2009).
*
-
Clayton RF, Rinaldi A, Kandyba EE, Edward M, Willberg C, Klenerman P, Patel AH. Liver cell lines for the study of hepatocyte functions and immunological response.
Liver Int. 25: 389-402 (2005).
*
-
Clee SM, Yandell BS, Schueler KM, Rabaglia ME, Richards OC, Raines SM, Kabara EA, Klass DM, Mui ET, Stapleton DS, Gray-Keller MP, Young MB, Stoehr JP, Lan H, Boronenkov I, Raess PW, Flowers MT, Attie AD. Positional cloning of Sorcs1, a type 2 diabetes quantitative trait locus.
Nat. Genet. 38: 688-693 (2006).
*
-
Cleland LG, Bell DA. The occurrence of systemic lupus erythematosus in two kindreds in association with selective IgA deficiency.
J. Rheumatol. 5: 288-293 (1978).
-
Clemens MG, Zhang JX. Regulation of sinusoidal perfusion: in vivo methodology and control by endothelins.
Semin. Liver Dis. 19: 383-396 (1999).
-
Clemenz M, Frost N, Schupp M, Caron S, Foryst-Ludwig A, Bohm C, Hartge M, Gust R, Staels B, Unger T, Kintscher U. Liver-specific peroxisome proliferator-activated receptor alpha target gene regulation by the angiotensin type 1 receptor blocker telmisartan.
Diabetes 57: 1405-1413 (2008).
*
-
Clemo NK, Collard TJ, Southern S, Edwards KD, Moorghen M, Packham G, Hague A, Paraskeva C, Williams AC. BAG-1 is up-regulated in colorectal tumour progression and promotes colorectal tumour cell survival through increased NF-kappaB activity.
Carcinogenesis 29: 849-857 (2008).
*
-
Clifford JL, Petkovich M, Chambon P, Lotan R. Modulation by retinoids of mRNA levels for nuclear retinoic acid receptors in murine melanoma cells.
Mol. Endocrinol. 4: 1546-1555 (1990).
-
Clifton IJ, Fletcher LA, Beggs CB, Denton M, Conway SP, Peckham DG. An aerobiological model of aerosol survival of different strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis.
J. Cyst. Fibros. Nov 26 [Epub ahead of print] (2009).
-
Clodfelter KH, Holloway MG, Hodor P, Park SH, Ray WJ, Waxman DJ. Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.
Mol. Endocrinol. 20: 1333-1351 (2006).
*
-
Clodfelter KH, Miles GD, Wauthier V, Holloway MG, Zhang X, Hodor P, Ray WJ, Waxman DJ. Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.
Physiol. Genomics 31: 63-74 (2007).
*
-
Cloosen S, Arnold J, Thio M, Bos GM, Kyewski B, Germeraad WT. Expression of tumor-associated differentiation antigens, MUC1 glycoforms and CEA, in human thymic epithelial cells: implications for self-tolerance and tumor therapy.
Cancer Res. 67: 3919-3926 (2007).
*
-
Cloutier A, Guindi C, Larivee P, Dubois CM, Amrani A, McDonald PP. Inflammatory cytokine production by human neutrophils involves C/EBP transcription factors.
J. Immunol. 182: 563-571 (2009).
*
-
Cobb BS, Hertweck A, Smith J, O'Connor E, Graf D, Cook T, Smale ST, Sakaguchi S, Livesey FJ, Fisher AG, Merkenschlager M. A role for Dicer in immune regulation.
J. Exp. Med. 203: 2519-2527 (2006).
*
-
Cobb JP, Mindrinos MN, Miller-Graziano C, Calvano SE, Baker HV, Xiao W, Laudanski K, Brownstein BH, Elson CM, Hayden DL, Herndon DN, Lowry SF, Maier RV, Schoenfeld DA, Moldawer LL, Davis RW, Tompkins RG, Baker HV, Bankey P, Billiar T, Brownstein BH, et al. Application of genome-wide expression analysis to human health and disease.
Proc. Natl. Acad. Sci. U.S.A. 102: 4801-4806 (2005).
*
-
Cobbold SP. The hidden truth about gene expression in Tregs: is it what you don't see that counts?
Eur. J. Immunol. 36: 1360-1363 (2006).
*
-
Cobrin GM, Abreu MT. Defects in mucosal immunity leading to Crohn's disease.
Immunol. Rev. 206: 277-295 (2005).
*
-
Coccia EM, Severa M, Giacomini E, Monneron D, Remoli ME, Julkunen I, Cella M, Lande R, Uze G. Viral infection and Toll-like receptor agonists induce a differential expression of type I and lambda interferons in human plasmacytoid and monocyte-derived dendritic cells.
Eur. J. Immunol. 34: 796-805 (2004).
*
-
Coeffier M, Marion R, Ducrotte P, Dechelotte P. Modulating effect of glutamine on IL-1beta-induced cytokine production by human gut.
Clin. Nutr. 22: 407-413 (2003).
-
Coelho LF, de Oliveira JG, de Oliveira DB, Guedes AC, Lanna CC, Prados RZ, Ferreira PC, Bonjardim CA, Kroon EG. Increased expression of 2'5'oligoadenylate synthetase and double-stranded RNA dependent protein kinase messenger RNAs on affected skin of systemic sclerosis patients.
Arch. Dermatol. Res. 299: 259-262 (2007).
*
-
Coelho SM, Vaisman M, Carvalho DP. Tumour re-differentiation effect of retinoic acid: a novel therapeutic approach for advanced thyroid cancer.
Curr. Pharm. Des. 11: 2525-2531 (2005).
-
Coen G. Vitamin D: an old prohormone with an emergent role in chronic kidney disease.
J. Nephrol. 21: 313-323 (2008).
-
Coffey F, Alabyev B, Manser T. Initial clonal expansion of germinal center B cells takes place at the perimeter of follicles.
Immunity 30: 599-609 (2009).
*
-
Coffey JC, Wang JH, Kelly R, Romics L Jr, O'Callaghan A, Fiuza C, Redmond HP. Tolerization with BLP down-regulates HMGB1 - a critical mediator of sepsis-related lethality.
J. Leukoc. Biol. 82: 906-914 (2007).
*
-
Cogan NG. Effects of persister formation on bacterial response to dosing.
J. Theor. Biol. 238: 694-703 (2006).
*
-
Coggins RP, Cawkwell L, Bell SM, Crockford GP, Quirke P, Finan PJ, Bishop DT. Association between family history and mismatch repair in colorectal cancer.
Gut 54: 636-642 (2005).
*
-
Cohavy O, Harth G, Horwitz M, Eggena M, Landers C, Sutton C, Targan SR, Braun J. Identification of a novel mycobacterial histone H1 homologue (HupB) as an antigenic target of pANCA monoclonal antibody and serum immunoglobulin A from patients with Crohn's disease.
Infect. Immun. 67: 6510-6517 (1999).
*
-
Cohavy O, Zhou J, Ware CF, Targan SR. LIGHT is constitutively expressed on T and NK cells in the human gut and can be induced by CD2-mediated signaling.
J. Immunol. 174: 646-653 (2005).
*
-
Cohen JC, Larson JE. Cystic fibrosis transmembrane conductance regulator (CFTR) dependent cytoskeletal tension during lung organogenesis.
Dev. Dyn. 235: 2736-2748 (2006).
-
Cohen JC, Larson JE, Killeen E, Love D, Takemaru KI. CFTR and Wnt/beta-catenin signaling in lung development.
BMC Dev. Biol. 8: 70 (2008).
*
-
Cohen Jr MM. Perspectives on RUNX genes: an update.
Am. J. Med. Genet. A. 149A: 2629-2646 (2009).
-
Cohly HH, Panja A. Immunological findings in autism.
Int. Rev. Neurobiol. 71: 317-341 (2005).
-
Colbert RA, Delay ML, Layh-Schmitt G, Sowders DP. HLA-B27 misfolding and spondyloarthropathies.
Prion 3: 15-26 (2009).
-
Coleman JD, Prabhu KS, Thompson JT, Reddy PS, Peters JM, Peterson BR, Reddy CC, Vanden Heuvel JP. The oxidative stress mediator 4-hydroxynonenal is an intracellular agonist of the nuclear receptor peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta).
Free Radic. Biol. Med. 42: 1155-1164 (2007).
-
Coleman SH, Madrid R, Van Damme N, Mitchell RS, Bouchet J, Servant C, Pillai S, Benichou S, Guatelli JC. Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif.
J. Virol. 80: 1837-1849 (2006).
*
-
Coles BF, Kadlubar FF. Human alpha class glutathione S-transferases: genetic polymorphism, expression, and susceptibility to disease.
Methods Enzymol. 401: 9-42 (2005).
-
Coletta DK, Balas B, Chavez AO, Baig M, Abdul-Ghani M, Kashyap S, Folli F, Tripathy D, Mandarino LJ, Cornell JE, Defronzo RA, Jenkinson CP. Effect of acute physiologic hyperinsulinemia on gene expression in human skeletal muscle in vivo.
Am. J. Physiol. Endocrinol. Metab. 294: E910-E917 (2008).
*
-
Colin S, Bourguignon E, Boullay AB, Tousaint JJ, Huet S, Caira F, Staels B, Lestavel S, Lobaccaro JM, Delerive P. Intestine-specific regulation of PPARalpha gene transcription by liver X receptors.
Endocrinology 149: 5128-5135 (2008).
*
-
Coll M, Martell M, Raurell I, Ezkurdia N, Cuenca S, Hernandez-Losa J, Esteban R, Guardia J, Bosch J, Genesca J. Atrophy of mesenteric sympathetic innervation may contribute to splanchnic vasodilation in rat portal hypertension.
Liver Int. Nov 30 [Epub ahead of print] (2009).
*
-
Coll T, Palomer X, Blanco-Vaca F, Escola-Gil JC, Sanchez RM, Laguna JC, Vazquez-Carrera M. Cyclooxygenase 2 inhibition exacerbates palmitate-induced inflammation and insulin resistance in skeletal muscle cells.
Endocrinology Dec 18 [Epub ahead of print] (2009).
*
-
Collett A, Higgs NB, Gironella M, Zeef LA, Hayes A, Salmo E, Haboubi N, Iovanna JL, Carlson GL, Warhurst G. Early molecular and functional changes in colonic epithelium that precede increased gut permeability during colitis development in mdr1a(-/-) mice.
Inflamm. Bowel Dis. 14: 620-631 (2008).
*
-
Colletti M, Cicchini C, Conigliaro A, Santangelo L, Alonzi T, Pasquini E, Tripodi M, Amicone L. Convergence of Wnt signaling on the HNF4alpha-driven transcription in controlling liver zonation.
Gastroenterology 137: 660-672 (2009).
*
-
Collier JD, Bennett MK, Hall A, Cattan AR, Lendrum R, Bassendine MF. Expression of glutathione S-transferases in normal and malignant pancreas: an immunohistochemical study.
Gut 35: 266-269 (1994).
*
-
Collier JD, Carpenter M, Burt AD, Bassendine MF. Expression of mutant p53 protein in hepatocellular carcinoma.
Gut 35: 98-100 (1994).
*
-
Collino M, Aragno M, Mastrocola R, Benetti E, Gallicchio M, Dianzani C, Danni O, Thiemermann C, Fantozzi R. Oxidative stress and inflammatory response evoked by transient cerebral ischemia/reperfusion: effects of the PPAR-alpha agonist WY14643.
Free Radic. Biol. Med. 41: 579-589 (2006).
-
Collino M, Patel NS, Thiemermann C. PPARs as new therapeutic targets for the treatment of cerebral ischemia/reperfusion injury.
Ther. Adv. Cardiovasc. Dis. 2: 179-197 (2008).
-
Collins CB, Ho J, Wilson TE, Wermers JD, Tlaxca JL, Lawrence MB, Solga M, Lannigan J, Rivera-Nieves J. CD44 deficiency attenuates chronic murine ileitis.
Gastroenterology 135: 1993-2002 (2008).
*
-
Collins JL, Fivush AM, Watson MA, Galardi CM, Lewis MC, Moore LB, Parks DJ, Wilson JG, Tippin TK, Binz JG, Plunket KD, Morgan DG, Beaudet EJ, Whitney KD, Kliewer SA, Willson TM. Identification of a nonsteroidal liver X receptor agonist through parallel array synthesis of tertiary amines.
J. Med. Chem. 45: 1963-1966 (2002).
*
-
Collins S, Lutz MA, Zarek PE, Anders RA, Kersh GJ, Powell JD. Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.
Eur. J. Immunol. 38: 528-536 (2008).
*
-
Collison LW, Workman CJ, Kuo TT, Boyd K, Wang Y, Vignali KM, Cross R, Sehy D, Blumberg RS, Vignali DA. The inhibitory cytokine IL-35 contributes to regulatory T-cell function.
Nature 450: 566-569 (2007).
*
-
Colliver DW, Crawford NP, Eichenberger MR, Zacharius W, Petras RE, Stromberg AJ, Galandiuk S. Molecular profiling of ulcerative colitis-associated neoplastic progression.
Exp. Mol. Pathol. 80: 1-10 (2006).
*
-
Colmenero J, Bataller R, Sancho-Bru P, Bellot P, Miquel R, Moreno M, Jares P, Bosch J, Arroyo V, Caballeria J, Gines P. Hepatic expression of candidate genes in patients with alcoholic hepatitis: correlation with disease severity.
Gastroenterology 132: 687-697 (2007).
*
-
Colnot S, Lambert M, Blin C, Thomasset M, Perret C. Identification of DNA sequences that bind retinoid X receptor-1,25(OH)2D3-receptor heterodimers with high affinity.
Mol. Cell. Endocrinol. 113: 89-98 (1995).
-
Colombara M, Antonini V, Riviera AP, Mainiero F, Strippoli R, Merola M, Fracasso G, Poffe O, Brutti N, Tridente G, Colombatti M, Ramarli D. Constitutive activation of p38 and ERK1/2 MAPKs in epithelial cells of myasthenic thymus leads to IL-6 and RANTES overexpression: effects on survival and migration of peripheral T and B cells.
J. Immunol. 175: 7021-7028 (2005).
*
-
Colombel JF. IBD: genotypes - phenotypes.
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 19 (2005). *
-
Colombo C. Liver disease in cystic fibrosis.
Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 31-33 (2006). *
-
Colombo C, Crosignani A, Apostolo MG, Marzano MT, Bettinardi N, Giunta A. Oral bile acids in cystic fibrosis-associated liver disease.
J. R. Soc. Med. 87 Suppl. 21: 20-24 (1994).
*
-
Colombo PL, Benedetti M, Tinozzi FP, Ticozzelli E, Maroni N, Di Sabatino A, Tinozzi S. Different approaches for medical or surgical management of Crohn's disease: the importance of the classification of Vienna.
Ann. Ital. Chir. 77: 485-496 (2006).
-
Colon AL, Madrigal JL, Menchen LA, Moro MA, Lizasoain I, Lorenzo P, Leza JC. Stress increases susceptibility to oxidative/nitrosative mucosal damage in an experimental model of colitis in rats.
Dig. Dis. Sci. 49: 1713-1721 (2004).
*
-
Colucci R, Blandizzi C, Bellini M, Ghisu N, Tonini M, Del Tacca M. The genetics of the serotonin transporter and irritable bowel syndrome.
Trends Mol. Med. 14: 295-304 (2008).
*
-
Columba-Cabezas S, Griguoli M, Rosicarelli B, Magliozzi R, Ria F, Serafini B, Aloisi F. Suppression of established experimental autoimmune encephalomyelitis and formation of meningeal lymphoid follicles by lymphotoxin beta receptor-Ig fusion protein.
J. Neuroimmunol. 179: 76-86 (2006).
-
Colville-Nash PR, Gilroy DW. Potential adverse effects of cyclooxygenase-2 inhibition: evidence from animal models of inflammation.
BioDrugs 15: 1-9 (2001).
-
Colvin RB, Smith RN. Antibody-mediated organ-allograft rejection.
Nat. Rev. Immunol. 5: 807-817 (2005).
*
-
Comabella M, Martin R. Genomics in multiple sclerosis - current state and future directions.
J. Neuroimmunol. 187: 1-8 (2007).
-
Combarros O, Infante J, Llorca J, Pena N, Fernandez-Viadero C, Berciano J. The chemokine receptor CCR5-Delta32 gene mutation is not protective against Alzheimer's disease.
Neurosci. Lett. 366: 312-314 (2004).
*
-
Comelli EM, Lariani S, Zwahlen MC, Fotopoulos G, Holzwarth JA, Cherbut C, Dorta G, Corthesy-Theulaz I, Grigorov M. Biomarkers of human gastrointestinal tract regions.
Mamm. Genome 20: 516-527 (2009).
*
-
Comerford KM, Wallace TJ, Karhausen J, Louis NA, Montalto MC, Colgan SP. Hypoxia-inducible factor-1-dependent regulation of the multidrug resistance (MDR1) gene.
Cancer Res. 62: 3387-3394 (2002).
*
-
Commerford SR, Vargas L, Dorfman SE, Mitro N, Rocheford EC, Mak PA, Li X, Kennedy P, Mullarkey TL, Saez E. Dissection of the insulin-sensitizing effect of liver X receptor ligands.
Mol. Endocrinol. 21: 3002-3112 (2007).
*
-
Compe E, Drane P, Laurent C, Diderich K, Braun C, Hoeijmakers JH, Egly JM. Dysregulation of the peroxisome proliferator-activated receptor target genes by XPD mutations.
Mol. Cell. Biol. 25: 6065-6076 (2005).
*
-
Comstock CE, Augello MA, Benito RP, Karch J, Tran TH, Utama FE, Tindall EA, Wang Y, Burd CJ, Groh EM, Hoang HN, Giles GG, Severi G, Hayes VM, Henderson BE, Le Marchand L, Kolonel LN, Haiman CA, Baffa R, Gomella LG, Knudsen ES, Rui H, Henshall SM, et al. Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer.
Clin. Cancer Res. 15: 5338-5349 (2009).
*
-
Conaway HH, Persson E, Halen M, Granholm S, Svensson O, Pettersson U, Lie A, Lerner UH. Retinoids inhibit differentiation of hematopoetic osteoclast progenitors.
FASEB J. 23: 3526-3538 (2009).
*
-
Conceicao N, Laize V, Simoes B, Pombinho AR, Cancela ML. Retinoic acid is a negative regulator of matrix Gla protein gene expression in teleost fish Sparus aurata.
Biochim. Biophys. Acta 1779: 28-39 (2008).
*
-
Conde I, Lobo MV, Zamora J, Perez J, Gonzalez FJ, Alba E, Fraile B, Paniagua R, Arenas MI. Human pregnane X receptor is expressed in human breast carcinomas, potential heterodimer formation between hPXR and RXR-alpha.
BMC Cancer 8: 174 (2008).
*
-
Conde I, Paniagua R, Fraile B, Ruiz A, Arenas MI. Expression of vitamin D3 receptor and retinoid receptors in human breast cancer: identification of potential heterodimeric receptors.
Int. J. Oncol. 25: 1183-1191 (2004).
-
Conese M, Boyd AC, Di Gioia S, Auriche C, Ascenzioni F. Genomic context vectors and artificial chromosomes for cystic fibrosis gene therapy.
Curr. Gene Ther. 7: 175-187 (2007).
-
Cong Y, Weaver CT, Elson CO. The mucosal adjuvanticity of cholera toxin involves enhancement of costimulatory activity by selective up-regulation of B7.2 expression.
J. Immunol. 159: 5301-5308 (1997).
-
Cong Y, Weaver CT, Lazenby A, Elson CO. Colitis induced by enteric bacterial antigen-specific CD4+ T cells requires CD40-CD40 ligand interactions for a sustained increase in mucosal IL-12.
J. Immunol. 165: 2173-2182 (2000).
*
-
Conrad B, Weissmahr RN, Boni J, Arcari R, Schupbach J, Mach B. A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes.
Cell 90: 303-313 (1997).
*
-
Conrad S, Kauffmann HM, Ito K, Deeley RG, Cole SP, Schrenk D. Identification of human multidrug resistance protein 1 (MRP1) mutations and characterization of a G671V substitution.
J. Hum. Genet. 46: 656-663 (2001).
-
Conroy ME, Walker WA. Intestinal immune health.
Nestle Nutr. Workshop Ser. Pediatr. Program 62: 111-125 (2008).
-
Conseil G, Deeley RG, Cole SP. Polymorphisms of MRP1 (ABCC1) and related ATP-dependent drug transporters.
Pharmacogenet. Genomics 15: 523-533 (2005).
-
Conseil G, Deeley RG, Cole SP. Functional importance of three basic residues clustered at the cytosolic interface of transmembrane helix 15 in the multidrug and organic anion transporter MRP1 (ABCC1).
J. Biol. Chem. 281: 43-50 (2006).
*
-
Constable PA, Lawrenson JG, Dolman DE, Arden GB, Abbott NJ. P-Glycoprotein expression in human retinal pigment epithelium cell lines.
Exp. Eye Res. 83: 24-30 (2006).
*
-
Constantin CE, Mair N, Sailer CA, Andratsch M, Xu ZZ, Blumer MJ, Scherbakov N, Davis JB, Bluethmann H, Ji RR, Kress M. Endogenous tumor necrosis factor alpha (TNFalpha) requires TNF receptor type 2 to generate heat hyperalgesia in a mouse cancer model.
J. Neurosci. 28: 5072-5081 (2008).
-
Constantin-Teodosiu D, Baker DJ, Constantin D, Greenhaff PL. PPARdelta agonism inhibits skeletal muscle PDC activity, mitochondrial ATP production and force generation during prolonged contraction.
J. Physiol. 587: 231-239 (2009).
*
-
Contardi E, Palmisano GL, Tazzari PL, Martelli AM, Fala F, Fabbi M, Kato T, Lucarelli E, Donati D, Polito L, Bolognesi A, Ricci F, Salvi S, Gargaglione V, Mantero S, Alberghini M, Ferrara GB, Pistillo MP. CTLA-4 is constitutively expressed on tumor cells and can trigger apoptosis upon ligand interaction.
Int. J. Cancer 117: 538-550 (2005).
*
-
Conti L, Cardone M, Varano B, Puddu P, Belardelli F, Gessani S. Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes.
Eur. J. Immunol. 38: 750-762 (2008).
*
-
Cooke A. Th17 cells in inflammatory conditions.
Rev. Diabet. Stud. 3: 72-75 (2006).
*
-
Cooke EL, Uings IJ, Xia CL, Woo P, Ray KP. Functional analysis of the interleukin-1-receptor-associated kinase (IRAK-1) in interleukin-1 beta-stimulated nuclear factor kappa B (NF-kappa B) pathway activation: IRAK-1 associates with the NF-kappa B essential modulator (NEMO) upon receptor …
Biochem. J. 359: 403-410 (2001).
*
-
Cookson W, Liang L, Abecasis G, Moffatt M, Lathrop M. Mapping complex disease traits with global gene expression.
Nat. Rev. Genet. 10: 184-194 (2009).
*
-
Coon CI, Fiering S, Gaudet J, Wyatt CA, Brinckerhoff CE. Site controlled transgenic mice validating increased expression from human matrix metalloproteinase (MMP-1) promoter due to a naturally occurring SNP.
Matrix Biol. 28: 425-431 (2009).
-
Cooper GS, Parks CG, Schur PS, Fraser PA. Occupational and environmental associations with antinuclear antibodies in a general population sample.
J. Toxicol. Environ. Health A. 69: 2063-2069 (2006).
-
Cooper JD, Walker NM, Smyth DJ, Downes K, Healy BC, Todd JA. Follow-up of 1715 SNPs from the Wellcome Trust Case Control Consortium genome-wide association study in type I diabetes families.
Genes Immun. 10: S85-S94 (2009).
-
Copland DA, Hussain K, Baalasubramanian S, Hughes TR, Morgan BP, Xu H, Dick AD, Nicholson LB. Systemic and local anti-C5 therapy reduces the disease severity in experimental autoimmune uveoretinitis.
Clin. Exp. Immunol. Dec 14 [Epub ahead of print] (2009).
*
-
Coppel RL, Gershwin ME. Primary biliary cirrhosis: the molecule and the mimic.
Immunol. Rev. 144: 17-49 (1995).
-
Coppi LC, Thomazzi SM, Ayrizono MD, Coy CS, Fagundes JJ, Goes JR, Franchi GC Jr, Nowill AE, Montes CG, Antunes E, Ferraz JG. Comparative study of eosinophil chemotaxis, adhesion, and degranulation in vitro in ulcerative colitis and Crohn's disease.
Inflamm. Bowel Dis. 13: 211-218 (2007).
*
-
Coppola G, Geschwind DH. Technology insight: querying the genome with microarrays-progress and hope for neurological disease.
Nat. Clin. Pract. Neurol. 2: 147-158 (2006).
-
Coppotelli G, Summers A, Chidakel A, Ross JM, Celi FS. Functional characterization of the 258 A/G (D2-ORFa-Gly3Asp) human type-2 deiodinase polymorphism: a naturally occurring variant increases the enzymatic activity by removing a putative repressor site in the 5' UTR of the gene.
Thyroid 16: 625-632 (2006).
-
Copreni E, Penzo M, Carrabino S, Conese M. Lentivirus-mediated gene transfer to the respiratory epithelium: a promising approach to gene therapy of cystic fibrosis.
Gene Ther. 11 Suppl. 1: S67-S75 (2004).
-
Coras R, Holsken A, Seufert S, Hauke J, Eyupoglu IY, Reichel M, Trankle C, Siebzehnrubl FA, Buslei R, Blumcke I, Hahnen E. The peroxisome proliferator-activated receptor-gamma agonist troglitazone inhibits transforming growth factor-beta-mediated glioma cell migration and brain invasion.
Mol. Cancer Ther. 6: 1745-1754 (2007).
*
-
Corazza N, Brunner T, Buri C, Rihs S, Imboden MA, Seibold I, Mueller C. Transmembrane tumor necrosis factor is a potent inducer of colitis even in the absence of its secreted form.
Gastroenterology 127: 816-825 (2004).
*
-
Corbaz A, ten Hove T, Herren S, Graber P, Schwartsburd B, Belzer I, Harrison J, Plitz T, Kosco-Vilbois MH, Kim SH, Dinarello CA, Novick D, van Deventer S, Chvatchko Y. IL-18-binding protein expression by endothelial cells and macrophages is up-regulated during active Crohn's disease.
J. Immunol. 168: 3608-3616 (2002).
*
-
Corbel C, Lemarchandel V, Thomas-Vaslin V, Pelus AS, Agboton C, Romeo PH. Neuropilin 1 and CD25 co-regulation during early murine thymic differentiation.
Dev. Comp. Immunol. 31: 1082-1094 (2007).
-
Cordeddu V, Di Schiavi E, Pennacchio LA, Ma'ayan A, Sarkozy A, Fodale V, Cecchetti S, Cardinale A, Martin J, Schackwitz W, Lipzen A, Zampino G, Mazzanti L, Digilio MC, Martinelli S, Flex E, Lepri F, Bartholdi D, Kutsche K, Ferrero GB, Anichini C, et al. Mutation of SHOC2 promotes aberrant protein N-myristoylation and causes Noonan-like syndrome with loose anagen hair.
Nat. Genet. 41: 1022-1026 (2009).
*
-
Cordero EA, Veit TD, da Silva MA, Jacques SM, Silla LM, Chies JA. HLA-G polymorphism influences the susceptibility to HCV infection in sickle cell disease patients.
Tissue Antigens 74: 308-313 (2009).
*
-
Cordery DV, Kishore U, Kyes S, Shafi MJ, Watkins KR, Williams TN, Marsh K, Urban BC. Characterization of a Plasmodium falciparum macrophage-migration inhibitory factor homologue.
J. Infect. Dis. 195: 905-912 (2007).
*
-
Cordonnier-Pratt MM, Liang C, Wang H, Kolychev DS, Sun F, Freeman R, Sullivan R, Pratt LH. MAGIC database and interfaces: an integrated package for gene discovery and expression.
Comp. Funct. Genomics 5: 268-275 (2004).
*
-
Corfield AP, Carroll D, Myerscough N, Probert CS. Mucins in the gastrointestinal tract in health and disease.
Front. Biosci. 6: D1321-D1357 (2001).
-
Corlazzoli F, Rossetti S, Bistulfi G, Ren M, Sacchi N. Derangement of a factor upstream of RARalpha triggers the repression of a pleiotropic epigenetic network.
PLoS ONE 4: e4305 (2009).
*
-
Cornelissen F, Mus AM, Asmawidjaja PS, van Hamburg JP, Tocker J, Lubberts E. Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORgammat in gammadelta T cells.
Arthritis Res. Ther. 11: R194 (2009).
*
-
Cornish EJ, Hassan SM, Martin JD, Li S, Merzdorf CS. A microarray screen for direct targets of Zic1 identifies an aquaporin gene, aqp-3b, expressed in the neural folds.
Dev. Dyn. 238: 1179-1194 (2009).
*
-
Cornwell PD, De Souza AT, Ulrich RG. Profiling of hepatic gene expression in rats treated with fibric acid analogs.
Mutat. Res. 549: 131-145 (2004).
-
Cornwell PD, Ulrich RG. Investigating the mechanistic basis for hepatic toxicity induced by an experimental chemokine receptor 5 (CCR5) antagonist using a compendium of gene expression profiles.
Toxicol. Pathol. 35: 576-588 (2007).
*
-
Corpechot C, Ping C, Wendum D, Matsuda F, Barbu V, Poupon R. Identification of a novel 974C-->G nonsense mutation of the MRP2/ABCC2 gene in a patient with Dubin-Johnson syndrome and analysis of the effects of rifampicin and ursodeoxycholic acid on serum bilirubin and bile acids.
Am. J. Gastroenterol. 101: 2427-2432 (2006).
*
-
Corr M, Boyle DL, Ronacher L, Flores N, Firestein GS. Synergistic benefit in inflammatory arthritis by targeting I kappaB kinase epsilon and interferon beta.
Ann. Rheum. Dis. 68: 257-263 (2009).
-
Corradini E, Garuti C, Montosi G, Ventura P, Andriopoulos B Jr, Lin HY, Pietrangelo A, Babitt JL. Bone morphogenetic protein signaling is impaired in an Hfe knockout mouse model of hemochromatosis.
Gastroenterology 137: 1489-1497 (2009).
*
-
Correa F, Docagne F, Clemente D, Mestre L, Becker C, Guaza C. Anandamide inhibits IL-12p40 production by acting on the promoter repressor element GA-12: possible involvement of the COX-2 metabolite, prostamide E 2.
Biochem. J. 409: 761-770 (2008).
*
-
Correa F, Docagne F, Mestre L, Clemente D, Hernangomez M, Loria F, Guaza C. A role for CB2 receptors in anandamide signalling pathways involved in the regulation of IL-12 and IL-23 in microglial cells.
Biochem. Pharmacol. 77: 86-100 (2009).
*
-
Correale J, Farez M. Monocyte-derived dendritic cells in multiple sclerosis: the effect of bacterial infection.
J. Neuroimmunol. 190: 177-189 (2007).
-
Correale J, Farez M, Gilmore W. Vaccines for multiple sclerosis: progress to date.
CNS Drugs 22: 175-198 (2008).
-
Correale J, Ysrraelit MC, Gaitan MI. Immunomodulatory effects of vitamin D in multiple sclerosis.
Brain 132: 1146-1160 (2009).
-
Correia M, Machado JC, Ristimaki A. Basic aspects of gastric cancer.
Helicobacter 14 Suppl. 1: 36-40 (2009).
*
-
Corte-Real J, Rodo J, Almeida P, Garcia J, Coutinho A, Demengeot J, Penha-Goncalves C. Irf4 is a positional and functional candidate gene for the control of serum IgM levels in the mouse.
Genes Immun. 10: 93-99 (2009).
*
-
Cortez DM, Feldman MD, Srinivas M, Valente AJ, Steffensen B, Vincenti M, Barnes JL, Chandrasekar B. Interleukin-17 stimulates MMP1 expression in primary human cardiac fibroblasts via p38 MAPK and ERK1/2-dependent C/EBPbeta, NF-kappaB, and AP-1 activation.
Am. J. Physiol. Heart Circ. Physiol. 293: H3356-H3365 (2007).
*
-
Cortez-Gonzalez X, Pellicciotta I, Gerloni M, Wheeler MC, Castiglioni P, Lenert P, Zanetti M. TLR9-independent activation of B lymphocytes by bacterial DNA.
DNA Cell Biol. 25: 253-261 (2006).
-
Corthesy-Theulaz I, den Dunnen JT, Ferre P, Geurts JM, Muller M, van Belzen N, van Ommen B. Nutrigenomics: the impact of biomics technology on nutrition research.
Ann. Nutr. Metab. 49: 355-365 (2005).
-
Cortina C, Palomo-Ponce S, Iglesias M, Fernandez-Masip JL, Vivancos A, Whissell G, Huma M, Peiro N, Gallego L, Jonkheer S, Davy A, Lloreta J, Sancho E, Batlle E. EphB-ephrin-B interactions suppress colorectal cancer progression by compartmentalizing tumor cells.
Nat. Genet. 39: 1376-1383 (2007).
*
-
Corton JC, Anderson SP, Stauber A. Central role of peroxisome proliferator-activated receptors in the actions of peroxisome proliferators.
Annu. Rev. Pharmacol. Toxicol. 40: 491-518 (2000).
*
-
Cortright DN, Szallasi A. Biochemical pharmacology of the vanilloid receptor TRPV1.
Eur. J. Biochem. 271: 1814-1819 (2004).
*
-
Corvol JC, Pelletier D, Henry RG, Caillier SJ, Wang J, Pappas D, Casazza S, Okuda DT, Hauser SL, Oksenberg JR, Baranzini SE. Abrogation of T cell quiescence characterizes patients at high risk for multiple sclerosis after the initial neurological event.
Proc. Natl. Acad. Sci. U.S.A. 105: 11839-11844 (2008).
*
-
Costa AC, Figueiredo C, Touati E. Pathogenesis of Helicobacter pylori infection.
Helicobacter 14 Suppl. 1: 15-20 (2009).
*
-
Costa CD, Hammes TO, Rohden F, Margis R, Bortolotto JW, Padoin AV, Mottin CC, Guaragna RM. SIRT1 transcription is decreased in visceral adipose tissue of morbidly obese patients with severe hepatic steatosis.
Obes. Surg. Dec 22 [Epub ahead of print] (2009).
-
Costa JE, Gomes CC, Cota LO, Pataro AL, Silva JF, Gomez RS, Costa FO. Polymorphism in the promoter region of the gene for 5-HTT in individuals with aggressive periodontitis.
J. Oral Sci. 50: 193-198 (2008).
*
-
Costa SC, Hirota SK, Takahashi MD, Andrade Jr H, Migliari DA. Oral lesions in 166 patients with cutaneous psoriasis: a controlled study.
Med. Oral Patol. Oral Cir. Bucal. 14: e371-e375 (2009).
*
-
Costa V, Foti D, Paonessa F, Chiefari E, Palaia L, Brunetti G, Gulletta E, Fusco A, Brunetti A. The insulin receptor: a new anticancer target for peroxisome proliferator-activated receptor-gamma (PPARgamma) and thiazolidinedione-PPARgamma agonists.
Endocr. Relat. Cancer 15: 325-335 (2008).
-
Coste AT, Turner V, Ischer F, Morschhauser J, Forche A, Semelcki A, Berman J, Bille J, Sanglard D. A mutation in Tac1p, a transcription factor regulating CDR1 and CDR2, is coupled with loss of heterozygosity at chromosome 5 to mediate antifungal resistance in Candida albicans.
Genetics 172: 2139-2156 (2006).
*
-
Costello MJ, Joyce SK, Abrahams VM. NOD protein expression and function in first trimester trophoblast cells.
Am. J. Reprod. Immunol. 57: 67-80 (2007).
*
-
Costello P, FitzGerald O. Disease mechanisms in psoriasis and psoriatic arthritis.
Curr. Rheumatol. Rep. 3: 419-427 (2001).
-
Costet P, Cariou B, Lambert G, Lalanne F, Lardeux B, Jarnoux AL, Grefhorst A, Staels B, Krempf M. Hepatic PCSK9 expression is regulated by nutritional status via insulin and sterol regulatory-element binding protein 1c.
J. Biol. Chem. 281: 6211-6218 (2006).
*
-
Cottone M, Cipolla C, Rosselli M. Epidemiology and pathogenesis of Crohn's disease.
Chir. Ital. 47: 1-7 (1995).
-
Couch FJ, Sinilnikova O, Vierkant RA, Pankratz VS, Fredericksen ZS, Stoppa-Lyonnet D, Coupier I, Hughes D, Hardouin A, Berthet P, Peock S, Cook M, Baynes C, Hodgson S, Morrison PJ, Porteous ME, Jakubowska A, Lubinski J, Gronwald J, Spurdle AB et al. AURKA F31I polymorphism and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a consortium of investigators of modifiers of BRCA1/2 study.
Cancer Epidemiol. Biomarkers Prev. 16: 1416-1421 (2007).
*
-
Couchie D, Lafdil F, Martin-Garcia N, Laperche Y, Zafrani ES, Mavier P. Expression and role of Gas6 protein and of its receptor Axl in hepatic regeneration from oval cells in the rat.
Gastroenterology 129: 1633-1642 (2005).
*
-
Couillard-Despres S, Quehl E, Altendorfer K, Karl C, Ploetz S, Bogdahn U, Winkler J, Aigner L. Human in vitro reporter model of neuronal development and early differentiation processes.
BMC Neurosci. 9: 31 (2008).
*
-
Coull DB, Lee FD, Anderson JH, McKee RF, Finlay IG, Dunlop MG. Long-term cancer risk of the anorectal cuff following restorative proctocolectomy assessed by p53 expression and cuff dysplasia.
Colorectal Dis. 9: 321-327 (2007).
*
-
Coulouarn C, Derambure C, Lefebvre G, Daveau R, Hiron M, Scotte M, Francois A, Daveau M, Salier JP. Global gene repression in hepatocellular carcinoma and fetal liver, and suppression of dudulin-2 mRNA as a possible marker for the cirrhosis-to-tumor transition.
J. Hepatol. 42: 860-869 (2005).
*
-
Coulouarn C, Factor VM, Thorgeirsson SS. Transforming growth factor-beta gene expression signature in mouse hepatocytes predicts clinical outcome in human cancer.
Hepatology 47: 2059-2067 (2008).
*
-
Coulouarn C, Gomez-Quiroz LE, Lee JS, Kaposi-Novak P, Conner EA, Goldina TA, Onishchenko GE, Factor VM, Thorgeirsson SS. Oncogene-specific gene expression signatures at preneoplastic stage in mice define distinct mechanisms of hepatocarcinogenesis.
Hepatology 44: 1003-1011 (2006).
*
-
Coulouarn C, Lefebvre G, Derambure C, Lequerre T, Scotte M, Francois A, Cellier D, Daveau M, Salier JP. Altered gene expression in acute systemic inflammation detected by complete coverage of the human liver transcriptome.
Hepatology 39: 353-364 (2004).
*
-
Couper KN, Blount DG, de Souza JB, Suffia I, Belkaid Y, Riley EM. Incomplete depletion and rapid regeneration of Foxp3+ regulatory T cells following anti-CD25 treatment in malaria-infected mice.
J. Immunol. 178: 4136-4146 (2007).
*
-
Couplan E, Le Cann M, Le Foll C, Corporeau C, Blondel M, Delarue J. Polyunsaturated fatty acids inhibit PI3K activity in a yeast-based model system.
Biotechnol. J. 4: 1190-1197 (2009).
-
Courselaud B, Pigeon C, Inoue Y, Inoue J, Gonzalez FJ, Leroyer P, Gilot D, Boudjema K, Guguen-Guillouzo C, Brissot P, Loreal O, Ilyin G. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism. Cross-talk between C/EBP pathway and iron metabolism.
J. Biol. Chem. 277: 41163-41170 (2002).
*
-
Courselaud B, Troadec MB, Fruchon S, Ilyin G, Borot N, Leroyer P, Coppin H, Brissot P, Roth MP, Loreal O. Strain and gender modulate hepatic hepcidin 1 and 2 mRNA expression in mice.
Blood Cells Mol. Dis. 32: 283-289 (2004).
-
Court MH, Hazarika S, Krishnaswamy S, Finel M, Williams JA. Novel polymorphic human UDP-glucuronosyltransferase (UGT) 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction.
Mol. Pharmacol. 74: 744-754 (2008).
*
-
Courtois G, Gilmore TD. Mutations in the NF-kappaB signaling pathway: implications for human disease.
Oncogene 25: 6831-6843 (2006).
*
-
Coury F, Annels N, Rivollier A, Olsson S, Santoro A, Speziani C, Azocar O, Flacher M, Djebali S, Tebib J, Brytting M, Egeler RM, Rabourdin-Combe C, Henter JI, Arico M, Delprat C. Langerhans cell histiocytosis reveals a new IL-17A-dependent pathway of dendritic cell fusion.
Nat. Med. 14: 81-87 (2008).
*
-
Coussens A, Timms PM, Boucher BJ, Venton TR, Ashcroft AT, Skolimowska KH, Newton SM, Wilkinson KA, Davidson RN, Griffiths CJ, Wilkinson RJ, Martineau AR. 1alpha,25-Dihydroxyvitamin D inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection.
Immunology 127: 539-548 (2009).
*
-
Coutinho A, Caramalho I, Seixas E, Demengeot J. Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection.
Curr. Top. Microbiol. Immunol. 293: 43-71 (2005).
-
Covacu R, Arvidsson L, Andersson A, Khademi M, Erlandsson-Harris H, Harris RA, Svensson MA, Olsson T, Brundin L. TLR activation induces TNF-alpha production from adult neural stem/progenitor cells.
J. Immunol. 182: 6889-6895 (2009).
-
Cowan CM, Jiang X, Hsu T, Soo C, Zhang B, Wang JZ, Kuroda S, Wu B, Zhang Z, Zhang X, Ting K. Synergistic effects of Nell-1 and BMP-2 on the osteogenic differentiation of myoblasts.
J. Bone Miner. Res. 22: 918-930 (2007).
*
-
Cowell RM, Blake KR, Russell JW. Localization of the transcriptional coactivator PGC-1alpha to GABAergic neurons during maturation of the rat brain.
J. Comp. Neurol. 502: 1-18 (2007).
-
Cox NJ. Human genetics: an expression of interest.
Nature 430: 733-734 (2004).
*
-
Cox SE, Doherty C, Atkinson SH, Nweneka CV, Fulford AJ, Ghattas H, Rockett KA, Kwiatkowski DP, Prentice AM. Haplotype association between haptoglobin (Hp2) and Hp promoter SNP (A-61C) may explain previous controversy of haptoglobin and malaria protection.
PLoS ONE 2: e362 (2007).
*
-
Cox SW, Ebersole LE, Carpenter GH, Proctor GB. Effects of autonomic agonists and immunomodulatory cytokines on polymeric immunoglobulin receptor expression by cultured rat and human salivary and colonic cell lines.
Arch. Oral Biol. 52: 411-416 (2007).
-
Coyle AT, O'keeffe MB, Kinsella BT. 15-Deoxy delta-prostaglandin J suppresses transcription by promoter 3 of the human thromboxane A receptor gene through peroxisome proliferator-activated receptor gamma in human erythroleukemia cells.
FEBS J. 272: 4754-4773 (2005).
*
-
Coyne GS, Kenny DA, Childs S, Sreenan JM, Waters SM. Dietary n-3 polyunsaturated fatty acids alter the expression of genes involved in prostaglandin biosynthesis in the bovine uterus.
Theriogenology 70: 772-782 (2008).
-
Cozar-Castellano I, Del Valle Machargo M, Trujillo E, Arteaga MF, Gonzalez T, Martin-Vasallo P, Avila J. hIscA: a protein implicated in the biogenesis of iron-sulfur clusters.
Biochim. Biophys. Acta 1700: 179-188 (2004).
*
-
Cozzolino M, Gallieni M, Brancaccio D, Arcidiacono T, Bianchi G, Vezzoli G. Vitamin D retains an important role in the pathogenesis and management of secondary hyperparathyroidism in chronic v.
J. Nephrol. 19: 566-577 (2006).
-
Cozzolino M, Pasho S, Fallabrino G, Olivi L, Gallieni M, Brancaccio D. Pathogenesis of secondary hyperparathyroidism.
Int. J. Artif. Organs 32: 75-80 (2009).
-
Cozzone D, Debard C, Dif N, Ricard N, Disse E, Vouillarmet J, Rabasa-Lhoret R, Laville M, Pruneau D, Rieusset J, Lefai E, Vidal H. Activation of liver X receptors promotes lipid accumulation but does not alter insulin action in human skeletal muscle cells.
Diabetologia 49: 990-999 (2006).
*
-
Crabe S, Guay-Giroux A, Tormo AJ, Duluc D, Lissilaa R, Guilhot F, Mavoungou-Bigouagou U, Lefouili F, Cognet I, Ferlin W, Elson G, Jeannin P, Gauchat JF. The IL-27 p28 subunit binds cytokine-like factor 1 to form a cytokine regulating NK and T cell activities requiring IL-6R for signaling.
J. Immunol. 183: 7692-7702 (2009).
-
Cragnolini JJ, Garcia-Medel N, Lopez de Castro JA. Endogenous processing and presentation of T-cell epitopes from Chlamydia trachomatis with relevance in HLA-B27-associated reactive arthritis.
Mol. Cell. Proteomics 8: 1850-1859 (2009).
*
-
Cragnolini JJ, Lopez de Castro JA. Identification of endogenously presented peptides from Chlamydia trachomatis with high homology to human proteins and to a natural self-ligand of HLA-B27.
Mol. Cell. Proteomics 7: 170-180 (2008).
*
-
Craig D, Robins G, Howdle PD. Advances in celiac disease.
Curr. Opin. Gastroenterol. 23: 142-148 (2007).
-
Cras A, Darsin-Bettinger D, Balitrand N, Cassinat B, Soulie A, Toubert ME, Delva L, Chomienne C. Epigenetic patterns of the retinoic acid receptor beta2 promoter in retinoic acid-resistant thyroid cancer cells.
Oncogene 26: 4018-4024 (2007).
*
-
Craven NM, Jackson CW, Kirby B, Perrey C, Pravica V, Hutchinson IV, Griffiths CE. Cytokine gene polymorphisms in psoriasis.
Br. J. Dermatol. 144: 849-853 (2001).
*
-
Crawford MA. Docosahexaenoic acid in neural signaling systems.
Nutr. Health 18: 263-276 (2006).
-
Crawford MA, Golfetto I, Ghebremeskel K, Min Y, Moodley T, Poston L, Phylactos A, Cunnane S, Schmidt W. The potential role for arachidonic and docosahexaenoic acids in protection against some central nervous system injuries in preterm infants.
Lipids 38: 303-315 (2003).
-
Crawford NP, Qian X, Ziogas A, Papageorge AG, Boersma BJ, Walker RC, Lukes L, Rowe WL, Zhang J, Ambs S, Lowy DR, Anton-Culver H, Hunter KW. Rrp1b, a new candidate susceptibility gene for breast cancer progression and metastasis.
PLoS Genet. 3: e214 (2007).
*
-
Crellin NK, Garcia RV, Levings MK. Flow cytometry-based methods for studying signaling in human CD4(+)CD25(+)FOXP3(+) T regulatory cells.
J. Immunol. Methods 324: 92-104 (2007).
*
-
Crespo HJ, Cabral MG, Teixeira AV, Lau JT, Trindade H, Videira PA. Effect of sialic acid loss on dendritic cell maturation.
Immunology 128: e621-e631 (2009).
-
Crettaz J, Berraondo P, Mauleon I, Ochoa L, Shankar V, Barajas M, van Rooijen N, Kochanek S, Qian C, Prieto J, Hernandez-Alcoceba R, Gonzalez-Aseguinolaza G. Intrahepatic injection of adenovirus reduces inflammation and increases gene transfer and therapeutic effect in mice.
Hepatology 44: 623-632 (2006).
*
-
Creusot RJ, Yaghoubi SS, Kodama K, Dang DN, Dang VH, Breckpot K, Thielemans K, Gambhir SS, Fathman CG. Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice.
Clin. Immunol. 127: 176-187 (2008).
*
-
Crisafulli C, Cuzzocrea S. The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.
Shock 32: 62-73 (2009).
-
Crisafulli C, Cuzzocrea S. The role of endogenous and exogenous ligands for the peroxisome proliferator-activated receptor alpha (PPAR-alpha) in the regulation of inflammation in macrophages.
Shock 32: 62-73 (2009).
-
Crisafulli C, Di Paola R, Mazzon E, Paterniti I, Galuppo M, Genovese T, Bramanti P, Cappellani Ddagger A, Cuzzocrea S. Liver X receptor agonist treatment reduced splanchnic ischemia and reperfusion injury.
J. Leukoc. Biol. Dec 22 [Epub ahead of print] (2009).
*
-
Crisafulli C, Galuppo M, Cuzzocrea S. Effects of genetic and pharmacological inhibition of TNF-alpha in the regulation of inflammation in macrophages.
Pharmacol. Res. 60: 332-340 (2009).
*
-
Crisi GM, Marconi SA, Rockwell GF, Braden GL, Campfield TJ. Immuno-localization of CD44 and osteopontin in developing human kidney.
Pediatr. Res. 65: 79-84 (2009).
*
-
Crispín JC, Liossis SN, Kis-Toth K, Lieberman LA, Kyttaris VC, Juang YT, Tsokos GC. Pathogenesis of human systemic lupus erythematosus: recent advances.
Trends Mol. Med. Feb 3 [Epub ahead of print] (2010).
*
-
Crispín JC, Tsokos GC. Human TCR-alphabeta+ CD4- CD8- T cells can derive from CD8+ T cells and display an inflammatory effector phenotype.
J. Immunol. 183: 4675-4681 (2009).
-
Crisponi L, Crisponi G, Meloni A, Toliat MR, Nurnberg G, Usala G, Uda M, Masala M, Hohne W, Becker C, Marongiu M, Chiappe F, Kleta R, Rauch A, Wollnik B, Strasser F, Reese T, Jakobs C, Kurlemann G, Cao A, Nurnberg P, Rutsch F. Crisponi syndrome is caused by mutations in the CRLF1 gene and is allelic to cold-induced sweating syndrome type 1.
Am. J. Hum. Genet. 80: 971-981 (2007).
*
-
Crocenzi FA, Mottino AD, Roma MG. Regulation of synthesis and trafficking of canalicular transporters and its alteration in acquired hepatocellular cholestasis. Experimental therapeutic strategies for its prevention.
Curr. Med. Chem. 11: 501-524 (2004).
-
Croitoru-Lamoury J, Lamoury FM, Zaunders JJ, Veas LA, Brew BJ. Human mesenchymal stem cells constitutively express chemokines and chemokine receptors that can be upregulated by cytokines, IFN-beta, and copaxone.
J. Interferon Cytokine Res. 27: 53-64 (2007).
-
Croker BP, Gilkeson G, Morel L. Genetic interactions between susceptibility loci reveal epistatic pathogenic networks in murine lupus.
Genes Immun. 4: 575-585 (2003).
*
-
Croker JA, Kimberly RP. SLE: challenges and candidates in human disease.
Trends Immunol. 26: 580-586 (2005).
*
-
Cron RQ. CD154 transcriptional regulation in primary human CD4 T cells.
Immunol. Res. 27: 185-202 (2003).
*
-
Cron RQ, Bandyopadhyay R, Genin A, Brunner M, Kersh GJ, Yin J, Finkel TH, Crow MK. Early growth response-1 is required for CD154 transcription.
J. Immunol. 176: 811-818 (2006).
*
-
Cronauer MV, Ince Y, Engers R, Rinnab L, Weidemann W, Suschek CV, Burchardt M, Kleinert H, Wiedenmann J, Sies H, Ackermann R, Kroncke KD. Nitric oxide-mediated inhibition of androgen receptor activity: possible implications for prostate cancer progression.
Oncogene 26: 1875-1884 (2007).
*
-
Cronican AA, Fitz NF, Pham T, Fogg A, Kifer B, Koldamova R, Lefterov I. Proton pump inhibitor lansoprazole is a nuclear liver X receptor agonist.
Biochem. Pharmacol. Jan 7 [Epub ahead of print] (2010).
*
-
Crosby MB, Svenson J, Gilkeson GS, Nowling TK. A novel PPAR response element in the murine iNOS promoter.
Mol. Immunol. 42: 1303-1310 (2005).
*
-
Crouthamel MH, Wu D, Yang Z, Ho RJ. A novel MDR1 G1199T variant alters drug resistance and efflux transport activity of P-glycoprotein in recombinant Hek cells.
J. Pharm. Sci. 95: 2767-2777 (2006).
*
-
Crow MK. Long interspersed nuclear elements (LINE-1): potential triggers of systemic autoimmune disease.
Autoimmunity Dec 7 [Epub ahead of print] (2009).
-
Crow MK. Interferon pathway activation in systemic lupus erythematosus.
Curr. Rheumatol. Rep. 7: 463-468 (2005).
-
Crowe DL, Chandraratna RA. A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands.
Breast Cancer Res. 6: R546-R555 (2004).
*
-
Crowley SD, Vasievich MP, Ruiz P, Gould SK, Parsons KK, Pazmino AK, Facemire C, Chen BJ, Kim HS, Tran TT, Pisetsky DS, Barisoni L, Prieto-Carrasquero MC, Jeansson M, Foster MH, Coffman TM. Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis.
J. Clin. Invest. 119: 943-953 (2009).
*
-
Crowley-Weber CL, Payne CM, Gleason-Guzman M, Watts GS, Futscher B, Waltmire CN, Crowley C, Dvorakova K, Bernstein C, Craven M, Garewal H, Bernstein H. Development and molecular characterization of HCT-116 cell lines resistant to the tumor promoter and multiple stress-inducer, deoxycholate.
Carcinogenesis 23: 2063-2080 (2002).
*
-
Croxford AL, Kurschus FC, Waisman A. Cutting edge: an IL-17F-CreEYFP reporter mouse allows fate mapping of Th17 cells.
J. Immunol. 182: 1237-1241 (2009).
-
Crozat K, Vivier E, Dalod M. Crosstalk between components of the innate immune system: promoting anti-microbial defenses and avoiding immunopathologies.
Immunol. Rev. 227: 129-149 (2009).
*
-
Cruickshank SM, Wakenshaw L, Cardone J, Howdle PD, Murray PJ, Carding SR. Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival.
World J. Gastroenterol. 14: 5834-5841 (2008).
*
-
Cruz-Garcia L, Minghetti M, Navarro I, Tocher DR. Molecular cloning, tissue expression and regulation of liver X receptor (LXR) transcription factors of Atlantic salmon (Salmo salar) and rainbow trout (Oncorhynchus mykiss).
Comp. Biochem. Physiol. B. Biochem. Mol. Biol. Feb 4 [Epub ahead of print] (2009).
*
-
Csanaky IL, Aleksunes LM, Tanaka Y, Klaassen CD. Role of hepatic transporters in prevention of bile acid toxicity after partial hepatectomy in mice.
Am. J. Physiol. Gastrointest. Liver Physiol. 297: G419-G433 (2009).
*
-
Cserepes J, Szentpetery Z, Seres L, Ozvegy-Laczka C, Langmann T, Schmitz G, Glavinas H, Klein I, Homolya L, Varadi A, Sarkadi B, Elkind NB. Functional expression and characterization of the human ABCG1 and ABCG4 proteins: indications for heterodimerization.
Biochem. Biophys. Res. Commun. 320: 860-867 (2004).
*
-
Csernok E, Schmitt WH, Ernst M, Bainton DF, Gross WL. Membrane surface proteinase 3 expression and intracytoplasmic immunoglobulin on neutrophils from patients with ANCA-associated vasculitides.
Adv. Exp. Med. Biol. 336: 45-50 (1993).
-
Csernok E, Szymkowiak CH, Mistry N, Daha MR, Gross WL, Kekow J. Transforming growth factor-beta (TGF-beta) expression and interaction with proteinase 3 (PR3) in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis.
Clin. Exp. Immunol. 105: 104-111 (1996).
*
-
Csillag C, Borup R, Olsen J, Nielsen FC, Nielsen OH. Treatment response and colonic gene expression in patients with Crohn's disease.
Scand. J. Gastroenterol. 42: 834-840 (2007).
*
-
Csillag C, Nielsen OH, Borup R, Nielsen FC, Olsen J. Clinical phenotype and gene expression profile in Crohn's disease.
Am. J. Physiol. Gastrointest. Liver Physiol. 292: G298-G304 (2007).
*
-
Csillag C, Nielsen OH, Borup R, Olsen J, Bjerrum JT, Nielsen FC. CARD15 status and familial predisposition for Crohn's disease and colonic gene expression.
Dig. Dis. Sci. 52: 1783-1789 (2007).
*
-
Csillag C, Nielsen OH, Vainer B, Olsen J, Dieckgraefe BK, Hendel J, Vind I, Dupuy C, Nielsen FC, Borup R. Expression of the genes dual oxidase 2, lipocalin 2 and regenerating islet-derived 1 alpha in Crohn's disease.
Scand. J. Gastroenterol. 42: 454-463 (2007).
*
-
Cua DJ, Sherlock J, Chen Y, Murphy CA, Joyce B, Seymour B, Lucian L, To W, Kwan S, Churakova T, Zurawski S, Wiekowski M, Lira SA, Gorman D, Kastelein RA, Sedgwick JD. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain.
Nature 421: 744-748 (2003).
*
-
Cuda CM, Wan S, Sobel ES, Croker BP, Morel L. Murine lupus susceptibility locus Sle1a controls regulatory T cell number and function through multiple mechanisms.
J. Immunol. 179: 7439-7447 (2007).
*
-
Cudrici C, Ito T, Zafranskaia E, Weerth S, Rus V, Chen H, Niculescu F, Soloviova K, Tegla C, Gherman A, Raine CS, Shin ML, Rus H. Complement C5 regulates the expression of insulin-like growth factor binding proteins in chronic experimental allergic encephalomyelitis.
J. Neuroimmunol. 203: 94-103 (2008).
-
Cuenca J, Cuchacovich M, Perez C, Ferreira L, Aguirre A, Schiattino I, Soto L, Cruzat A, Salazar-Onfray F, Aguillon JC. The -308 polymorphism in the tumour necrosis factor (TNF) gene promoter region and ex vivo lipopolysaccharide-induced TNF expression and cytotoxic activity in Chilean patients with rheumatoid arthritis.
Rheumatology (Oxford) 42: 308-313 (2003).
*
-
Cuenca J, Martin-Sanz P, Alvarez-Barrientos AM, Bosca L, Goren N. Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis.
Am. J. Pathol. 169: 1567-1576 (2006).
*
-
Cuenca J, Perez CA, Aguirre AJ, Schiattino I, Aguillon JC. Genetic polymorphism at position-308 in the promoter region of the tumor necrosis factor (TNF): implications of its allelic distribution on susceptibility or resistance to diseases in the Chilean population.
Biol. Res. 34: 237-241 (2001).
-
Cuesta N, Nhu QM, Zudaire E, Polumuri S, Cuttitta F, Vogel SN. IFN regulatory factor-2 regulates macrophage apoptosis through a STAT1/3- and caspase-1-dependent mechanism.
J. Immunol. 178: 3602-3611 (2007).
*
-
Cuff M, Dyer J, Jones M, Shirazi-Beechey S. The human colonic monocarboxylate transporter isoform 1: its potential importance to colonic tissue homeostasis.
Gastroenterology 128: 676-686 (2005).
*
-
Cui G, Olsen T, Christiansen I, Vonen B, Florholmen J, Goll R. Improvement of real-time polymerase chain reaction for quantifying TNF-alpha mRNA expression in inflamed colorectal mucosa: an approach to optimize procedures for clinical use.
Scand. J. Clin. Lab. Invest. 66: 249-259 (2006).
*
-
Cui G, Yuan A, Goll R, Olsen T, Husebekk A, Vonen B, Florholmen J. Distinct changes of dendritic cell number and IL-12 mRNA level in adjacent mucosa throughout the colorectal adenoma-carcinoma sequence.
Cancer Immunol. Immunother. 56: 1993-2001 (2007).
-
Cui J, Heard TS, Yu J, Lo JL, Huang L, Li Y, Schaeffer JM, Wright SD. The amino acid residues asparagine 354 and isoleucine 372 of human farnesoid X receptor confer the receptor with high sensitivity to chenodeoxycholate.
J. Biol. Chem. 277: 25963-25969 (2002).
*
-
Cui J, Huang L, Zhao A, Lew JL, Yu J, Sahoo S, Meinke PT, Royo I, Pelaez F, Wright SD. Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.
J. Biol. Chem. 278: 10214-10220 (2003).
*
-
Cui J, Lew J-L, Zhao A, Huang L, Wright SD. The farnesoid X receptor controls gene expression in a ligand and promoter-selective fashion.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 32. June 18-19 (2004). *
-
Cui M, Klopot A, Jiang Y, Fleet JC. The effect of differentiation on 1,25 dihydroxyvitamin D-mediated gene expression in the enterocyte-like cell line, Caco-2.
J. Cell. Physiol. 218: 113-121 (2009).
*
-
Cui M, Zhao Y, Hance KW, Shao A, Wood RJ, Fleet JC. Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2.
J. Cell. Physiol. 219: 132-142 (2009).
*
-
Cui T, Schopfer FJ, Zhang J, Chen K, Ichikawa T, Baker PR, Batthyany C, Chacko BK, Feng X, Patel RP, Agarwal A, Freeman BA, Chen YE. Nitrated fatty acids: endogenous anti-inflammatory signaling mediators.
J. Biol. Chem. 281: 35686-35698 (2006).
*
-
Cui Y, Cheng X, Miao Weaver Y, Klaassen CD. Tissue distribution, gender-divergent expression, ontogeny and chemical induction of multidrug resistance transporter genes (Mdr1a, Mdr1b, Mdr2) in mice.
Drug Metab. Dispos. 37: 203-210 (2009).
*
-
Cui Y, Freedman JH. Cadmium induces retinoic acid signaling by regulating retinoic acid metabolic gene expression.
J. Biol. Chem. 284: 24925-24932 (2009).
*
-
Cui Y, Konig J, Nies AT, Pfannschmidt M, Hergt M, Franke WW, Alt W, Moll R, Keppler D. Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.
Lab. Invest. 83: 527-538 (2003).
-
Cui YH, Liu TS, Zhuang RY, Gao HJ, Li H. Polymorphism of thymidylate synthase gene and chemosensitivity of 5-fluorouracil regimen in metastatic gastrointestinal cancer.
J. Dig. Dis. 10: 118-123 (2009).
*
-
Cui YJ, Aleksunes LM, Tanaka Y, Goedken MJ, Klaassen CD. Compensatory induction of liver efflux transporters in response to ANIT-induced liver injury is impaired in FXR-null mice.
Toxicol. Sci. 110: 47-60 (2009).
*
-
Cukovic-Cavka S, Vermeire S, Hrstic I, Claessens G, Kolacek S, Jakic-Razumovic J, Krznaric Z, Grubelic K, Radic D, Misak Z, Jadresin O, Rutgeerts P, Vucelic B. NOD2/CARD15 mutations in Croatian patients with Crohn's disease: prevalence and genotype-phenotype relationship.
Eur. J. Gastroenterol. Hepatol. 18: 895-899 (2006).
-
Cullen S, Chapman R. Chapter 19. Sclerosing cholangitis: primary and secondary.
In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 249-261 (2007). *
-
Cullinane AR, Straatman-Iwanowska A, Seo JK, Ko JS, Song KS, Gizewska M, Gruszfeld D, Gliwicz D, Tuysuz B, Erdemir G, Sougrat R, Wakabayashi Y, Hinds R, Barnicoat A, Mandel H, Chitayat D, Fischler B, Garcia-Cazorla A, Knisely AS, Kelly DA, Maher ER, Gisse. Molecular investigations to improve diagnostic accuracy in patients with ARC syndrome.
Hum. Mutat. 30: E330-E337 (2009).
*
-
Culpan D, Cram D, Chalmers K, Cornish A, Palmer L, Palmer J, Hughes A, Passmore P, Craigs D, Wilcock GK, Kehoe PG, Love S. TNFR-associated factor-2 (TRAF-2) in Alzheimer's disease.
Neurobiol. Aging 30: 1052-1060 (2009).
-
Cummins CL, Volle DH, Zhang Y, McDonald JG, Sion B, Lefrancois-Martinez AM, Caira F, Veyssiere G, Mangelsdorf DJ, Lobaccaro JM. Liver X receptors regulate adrenal cholesterol balance.
J. Clin. Invest. 116: 1902-1912 (2006).
*
-
Cummins EP, Comerford KM, Scholz C, Bruning U, Taylor CT. Hypoxic regulation of NF-kappaB signaling.
Methods Enzymol. 435: 479-492 (2007).
-
Cunard R, Ricote M, DiCampli D, Archer DC, Kahn DA, Glass CK, Kelly CJ. Regulation of cytokine expression by ligands of peroxisome proliferator activated receptors.
J. Immunol. 168: 2795-2802 (2002).
*
-
Cunha-Neto E, Nogueira LG, Teixeira PC, Ramasawmy R, Drigo SA, Goldberg AC, Fonseca SG, Bilate AM, Kalil J. Immunological and non-immunological effects of cytokines and chemokines in the pathogenesis of chronic Chagas disease cardiomyopathy.
Mem. Inst. Oswaldo Cruz 104: 252-258 (2009).
*
-
Cunningham S, Patterson CC, McDonnell G, Hawkins S, Vandenbroeck K. Haplotype analysis of the preprotachykinin-1 (TAC1) gene in multiple sclerosis.
Genes Immun. 6: 265-270 (2005).
*
-
Cunningham-Rundles C, Radigan L, Knight AK, Zhang L, Bauer L, Nakazawa A. TLR9 activation is defective in common variable immune deficiency.
J. Immunol. 176: 1978-1987 (2006).
*
-
Curfs DM, Ghesquiere SA, Vergouwe MN, van der Made I, Gijbels MJ, Greaves DR, Verbeek JS, Hofker MH, de Winther MP. Macrophage secretory phospholipase A2 group X enhances anti-inflammatory responses, promotes lipid accumulation, and contributes to aberrant lung pathology.
J. Biol. Chem. 283: 21640-21648 (2008).
*
-
Curnow SJ, Pryce K, Modi N, Knight B, Graham EM, Stewart JE, Fortune F, Stanford MR, Murray PI, Wallace GR. Serum cytokine profiles in Behcet's disease: is there a role for IL-15 in pathogenesis?
Immunol. Lett. 121: 7-12 (2008).
-
Curotto de Lafaille MA, Lino AC, Kutchukhidze N, Lafaille JJ. CD25- T cells generate CD25+Foxp3+ regulatory T cells by peripheral expansion.
J. Immunol. 173: 7259-7268 (2004).
*
-
Curran JE, Jowett JB, Elliott KS, Gao Y, Gluschenko K, Wang J, Azim DM, Cai G, Mahaney MC, Comuzzie AG, Dyer TD, Walder KR, Zimmet P, Maccluer JW, Collier GR, Kissebah AH, Blangero J. Genetic variation in selenoprotein S influences inflammatory response.
Nat. Genet. 37: 1234-1241 (2005).
*
-
Curtin P, McHugh KP, Zhou HY, Fluckiger R, Goldhaber P, Oppenheim FG, Salih E. Modulation of bone resorption by phosphorylation state of bone sialoprotein.
Biochemistry 48: 6876-6886 (2009).
*
-
Curtis MM, Way SS, Wilson CB. IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.
J. Immunol. 183: 381-387 (2009).
-
Custer M, Spindler B, Verrey F, Murer H, Biber J. Identification of a new gene product (diphor-1) regulated by dietary phosphate.
Am. J. Physiol. 273: F801-F806 (1997).
*
-
Cutolo M, Sulli A, Capellino S, Villaggio B, Montagna P, Seriolo B, Straub RH. Sex hormones influence on the immune system: basic and clinical aspects in autoimmunity.
Lupus 13: 635-638 (2004).
-
Cuvelier C, Mielants H, De Vos M, Quatacker J, Veys E. Idiopathic inflammatory bowel diseases: immunological hypothesis.
Acta Gastroenterol. Belg. 57: 292-299 (1994).
-
Cuzzocrea S. Role of nitric oxide and reactive oxygen species in arthritis.
Curr. Pharm. Des. 12: 3551-3570 (2006).
-
Cuzzocrea S, Di Paola R, Mazzon E, Genovese T, Muia C, Caputi AP. WY 14643, a potent exogenous PPAR-alpha ligand, reduces intestinal injury associated with splanchnic artery occlusion shock.
Shock 22: 340-346 (2004).
*
-
Cuzzocrea S, Mazzon E, Di Paola R, Peli A, Bonato A, Britti D, Genovese T, Mui C, Crisafulli C, Caputi AP. The role of the peroxisome proliferator-activated receptor-alpha (PPAR-alpha) in the regulation of acute inflammation.
J. Leukoc. Biol. 79: 999-1010 (2006).
*
-
Cvjeticanin T, Miljkovic D, Stojanovic I, Dekanski D, Stosic-Grujicic S. Dried leaf extract of Olea europaea ameliorates islet-directed autoimmunity in mice.
Br. J. Nutr. Dec 22 [Epub ahead of print] (2009).
*
-
Cvoro A, Tatomer D, Tee MK, Zogovic T, Harris HA, Leitman DC. Selective estrogen receptor agonists repress transcription of proinflammatory genes.
J. Immunol. 180: 630-636 (2008).
*
-
Cwinn MA, Jones SP, Kennedy SW. Exposure to perfluorooctane sulfonate or fenofibrate causes PPAR-alpha dependent transcriptional responses in chicken embryo hepatocytes.
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 148: 165-171 (2008).
*
-
Czaja AJ. Special clinical challenges in autoimmune hepatitis: the elderly, males, pregnancy, mild disease, fulminant onset, and nonwhite patients.
Semin. Liver Dis. 29: 315-330 (2009).
-
Czaja AJ. Autoimmune hepatitis: clinical and laboratory diagnosis.
Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 52-54 (2004). *
-
Czaja AJ. Autoimmune hepatitis - approach to diagnosis.
MedGenMed. 8: 55 (2006).
*
-
Czaja AJ. Autoimmune liver disease.
Curr. Opin. Gastroenterol. 17: 268-275 (2001).
-
Czaja AJ. Autoimmune liver disease.
Curr. Opin. Gastroenterol. 16: 262-270 (2000).
-
Czaja AJ. Autoimmune liver disease and rheumatic manifestations.
Curr. Opin. Rheumatol. 19: 74-80 (2007).
-
Czaja AJ. Autoimmune liver disease.
Curr. Opin. Gastroenterol. 18: 334-344 (2002).
-
Czaja AJ. Variant forms of autoimmune hepatitis.
Curr. Gastroenterol. Rep. 1: 63-70 (1999).
-
Czaja AJ. Extrahepatic immunologic features of chronic viral hepatitis.
Dig. Dis. 15: 125-144 (1997).
-
Czaja AJ. Autoimmune liver disease.
Curr. Opin. Gastroenterol. 20: 231-240 (2004).
-
Czaja AJ. Autoimmune liver disease.
Curr. Opin. Gastroenterol. 23: 255-262 (2007).
-
Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for immunological features in chronic liver diseases other than autoimmune hepatitis.
J. Hepatol. 24: 52-59 (1996).
*
-
Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Genetic predispositions for the immunological features of chronic active hepatitis.
Hepatology 18: 816-822 (1993).
-
Czaja AJ, Carpenter HA, Santrach PJ, Moore SB. Immunologic features and HLA associations in chronic viral hepatitis.
Gastroenterology 108: 157-164 (1995).
*
-
Czaja AJ, Cookson S, Constantini PK, Clare M, Underhill JA, Donaldson PT. Cytokine polymorphisms associated with clinical features and treatment outcome in type 1 autoimmune hepatitis.
Gastroenterology 117: 645-652 (1999).
*
-
Czaja AJ, Donaldson PT. Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis.
Immunol. Rev. 174: 250-259 (2000).
*
-
Czlonkowska A, Ciesielska A, Gromadzka G, Kurkowska-Jastrzebska I. Estrogen and cytokines production - the possible cause of gender differences in neurological diseases.
Curr. Pharm. Des. 11: 1017-1030 (2005).
-
Czochra P, Klopcic B, Meyer E, Herkel J, Garcia-Lazaro JF, Thieringer F, Schirmacher P, Biesterfeld S, Galle PR, Lohse AW, Kanzler S. Liver fibrosis induced by hepatic overexpression of PDGF-B in transgenic mice.
J. Hepatol. 45: 419-428 (2006).
*
-
D'Acquisto F, Ianaro A. From willow bark to peptides: the ever widening spectrum of NF-kappaB inhibitors.
Curr. Opin. Pharmacol. 6: 387-392 (2006).
-
D'Alise AM, Auyeung V, Feuerer M, Nishio J, Fontenot J, Benoist C, Mathis D. The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors.
Proc. Natl. Acad. Sci. U.S.A. 105: 19857-19862 (2008).
*
-
D'Amato G, Salzillo A, Piccolo A, D'Amato M, Liccardi G. A review of anti-IgE monoclonal antibody (omalizumab) as add on therapy for severe allergic (IgE-mediated) asthma.
Ther. Clin. Risk Manag. 3: 613-619 (2007).
*
-
D'Amato M, Bruce S, Bresso F, Zucchelli M, Ezer S, Pulkkinen V, Lindgren C, Astegiano M, Rizzetto M, Gionchetti P, Riegler G, Sostegni R, Daperno M, D'Alfonso S, Momigliano-Richiardi P, Torkvist L, Puolakkainen P, Lappalainen M, Paavola-Sakki P, et al. Neuropeptide S receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease.
Gastroenterology 133: 808-817 (2007).
*
-
D'Ambrosi N, Finocchi P, Apolloni S, Cozzolino M, Ferri A, Padovano V, Pietrini G, Carrì MT, Volonte C. The proinflammatory action of microglial P2 receptors is enhanced in SOD1 models for amyotrophic lateral sclerosis.
J. Immunol. 183: 4648-4656 (2009).
-
D'Ambrosio D, Albanesi C, Lang R, Girolomoni G, Sinigaglia F, Laudanna C. Quantitative differences in chemokine receptor engagement generate diversity in integrin-dependent lymphocyte adhesion.
J. Immunol. 169: 2303-2312 (2002).
*
-
D'Ambrosio D, Cippitelli M, Cocciolo MG, Mazzeo D, Di Lucia P, Lang R, Sinigaglia F, Panina-Bordignon P. Inhibition of IL-12 production by 1,25-dihydroxyvitamin D3. Involvement of NF-kappaB downregulation in transcriptional repression of the p40 gene.
J. Clin. Invest. 101: 252-262 (1998).
*
-
D'Angelo A, Coppola A, Madonna P, Fermo I, Pagano A, Mazzola G, Galli L, Cerbone AM. The role of vitamin B12 in fasting hyperhomocysteinemia and its interaction with the homozygous C677T mutation of the methylenetetrahydrofolate reductase (MTHFR) gene. A case-control study of patients with early-onset thrombotic events.
Thromb. Haemost. 83: 563-570 (2000).
*
-
D'Angelo G. Ethnic and genetic causes of neutropenia: clinical and therapeutic implications.
Lab. Hematol. 15: 25-29 (2009).
-
D'Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Deziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, Burns JL, Ramsey BW, Miller SI. Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients.
Mol. Microbiol. 64: 512-533 (2007).
*
-
D'Argenio G, Calvani M, Casamassimi A, Petillo O, Margarucci S, Rienzo M, Peluso I, Calvani R, Ciccodicola A, Caporaso N, Peluso G. Experimental colitis: decreased Octn2 and Atb0+ expression in rat colonocytes induces carnitine depletion that is reversible by carnitine-loaded liposomes.
FASEB J. 20: 2544-2546 (2006).
*
-
D'Argenio G, Calvani M, Della Valle N, Cosenza V, Di Matteo G, Giorgio P, Margarucci S, Petillo O, Jori FP, Galderisi U, Peluso G. Differential expression of multiple transglutaminases in human colon: impaired keratinocyte transglutaminase expression in ulcerative colitis.
Gut 54: 496-502 (2005).
*
-
D'Argenio G, Farrace MG, Cosenza V, De Ritis F, Della Valle N, Manguso F, Piacentini M. Expression of apoptosis-related proteins in rat with induced colitis.
Int. J. Colorectal Dis. 19: 451-460 (2004).
*
-
D'Arienzo R, Stefanile R, Maurano F, Luongo D, Bergamo P, Mazzarella G, Troncone R, Auricchio S, David C, Rossi M. A deregulated immune response to gliadin causes a decreased villus height in DQ8 transgenic mice.
Eur. J. Immunol. 39: 3552-3561 (2009).
*
-
D'Eon TM, Souza SC, Aronovitz M, Obin MS, Fried SK, Greenberg AS. Estrogen regulation of adiposity and fuel partitioning: evidence of genomic and non-genomic regulation of lipogenic and oxidative pathways.
J. Biol. Chem. 280: 36334-36341 (2005).
*
-
D'Haens G, Daperno M. Advances in medical therapy for Crohn's disease.
Curr. Gastroenterol. Rep. 4: 506-512 (2002).
-
D'Intino G, Perretta G, Taglioni A, Calistri M, Falzone C, Baroni M, Giardino L, Calza L. Endogenous stem and precursor cells for demyelinating diseases: an alternative for transplantation?
Neurol. Res. 28: 513-517 (2006).
-
da Silva MF, Nobrega A, Ribeiro RC, Levy MS, Ribeiro OG, Tambourgi DV, Sant'anna DA, da Silva AC. Genetic selection for resistance or susceptibility to oral tolerance imparts correlation to both immunoglobulin E level and mast cell number phenotypes with a profound impact on the atopic potential of the individual.
Clin. Exp. Allergy 36: 1399-1407 (2006).
*
-
Da Silva Morais A, Abarca-Quinones J, Horsmans Y, Starkel P, Leclercq IA. Peroxisome proliferated-activated receptor gamma ligand, pioglitazone, does not prevent hepatic fibrosis in mice.
Int. J. Mol. Med. 19: 105-112 (2007).
*
-
Daans M, Lories RJ, Luyten FP. Absence of GDF5 does not interfere with LPS Toll-like receptor signaling.
Clin. Exp. Rheumatol. 27: 495-498 (2009).
-
Dace DS, Khan AA, Stark JL, Kelly J, Cross AH, Apte RS. Interleukin-10 overexpression promotes Fas-ligand-dependent chronic macrophage-mediated demyelinating polyneuropathy.
PLoS One 4: e7121 (2009).
*
-
Dachrut S, Banthaisong S, Sripa M, Paeyao A, Ho C, Lee SA, Kosinski C, Patil MA, Zhang J, Chen X, Sripa B, Pairojkul C. DNA copy-number loss on 1p36.1 harboring RUNX3 with promoter hypermethylation and associated loss of RUNX3 expression in liver fluke-associated intrahepatic cholangiocarcinoma.
Asian Pac. J. Cancer Prev. 10: 575-582 (2009).
-
Dackor R, Caron K. Mice heterozygous for adrenomedullin exhibit a more extreme inflammatory response to endotoxin-induced septic shock.
Peptides 28: 2164-2170 (2007).
*
-
Dadi S, Le Noir S, Asnafi V, Beldjord K, Macintyre EA. Normal and pathological V(D)J recombination: contribution to the understanding of human lymphoid malignancies.
Adv. Exp. Med. Biol. 650: 180-194 (2009).
-
Dagher I, Nguyen TH, Groyer-Picard MT, Lainas P, Mainot S, Guettier C, Pariente D, Franco D, Weber A. Efficient hepatocyte engraftment and long-term transgene expression after reversible portal embolization in nonhuman primates.
Hepatology 49: 950-959 (2009).
*
-
Dagia NM, Agarwal G, Kamath DV, Chetrapal-Kunwar A, Gupte RD, Jadhav MG, Dadarkar SS, Trivedi J, Kulkarni-Almeida AA, Kharas F, Fonseca LC, Kumar S, Bhonde MR. A preferential p110alpha/gamma PI3K inhibitor attenuates experimental inflammation by suppressing the production of proinflammatory mediators in NF-kappaB dependent manner.
Am. J. Physiol. Cell Physiol. Jan 20 [Epub ahead of print] (2010).
*
-
Daginakatte GC, Gadzinski A, Emnett RJ, Stark JL, Gonzales ER, Yan P, Lee JM, Cross AH, Gutmann DH. Expression profiling identifies a molecular signature of reactive astrocytes stimulated by cyclic AMP or proinflammatory cytokines.
Exp. Neurol. 210: 261-267 (2008).
-
Dahlman I, Nilsson M, Jiao H, Hoffstedt J, Lindgren CM, Humphreys K, Kere J, Gustafsson JA, Arner P, Dahlman-Wright K. Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity.
Pharmacogenet. Genomics 16: 881-889 (2006).
-
Dahlman-Wright K, Zhao C. LXR in cholesterol metabolism.
J. Endocrinol. Oct 16 [Epub ahead of print] (2009).
*
-
Dai G, Chou N, He L, Gyamfi MA, Mendy AJ, Slitt AL, Klaassen CD, Wan YJ. RXRalpha regulates the expression of glutathione S-transferase genes and modulates acetaminophen-glutathione conjugation in mouse liver.
Mol. Pharmacol. 68: 1590-1596 (2005).
*
-
Dai G, He L, Bu P, Wan YJ. Pregnane X receptor is essential for normal progression of liver regeneration.
Hepatology 47: 1277-1287 (2008).
*
-
Dai H, Dai Z. The role of tryptophan catabolism in acquisition and effector function of memory T cells.
Curr. Opin. Organ Transplant. 13: 31-35 (2008).
-
Dai J, Liu B, Cua DJ, Li Z. Essential roles of IL-12 and dendritic cells but not IL-23 and macrophages in lupus-like diseases initiated by cell surface HSP gp96.
Eur. J. Immunol. 37: 706-715 (2007).
*
-
Dai J, Peng L, Fan K, Wang H, Wei R, Ji G, Cai J, Lu B, Li B, Zhang D, Kang Y, Tan M, Qian W, Guo Y. Osteopontin induces angiogenesis through activation of PI3K/AKT and ERK1/2 in endothelial cells.
Oncogene 28: 3412-3422 (2009).
*
-
Dai JY, Defrances MC, Zou C, Johnson CJ, Zarnegar R. The Met protooncogene is a transcriptional target of NFkappaB: implications for cell survival.
J. Cell. Biochem. 107: 1222-1236 (2009).
*
-
Dai L, Gu L, Ding C, Qiu L, Di W. TWEAK promotes ovarian cancer cell metastasis via NF-kappaB pathway activation and VEGF expression.
Cancer Lett. 283: 159-167 (2009).
-
Dai M, Wang P, Boyd AD, Kostov G, Athey B, Jones EG, Bunney WE, Myers RM, Speed TP, Akil H, Watson SJ, Meng F. Evolving gene/transcript definitions significantly alter the interpretation of GeneChip data.
Nucleic Acids Res. 33: e175 (2005).
*
-
Dai S, Hirayama T, Abbas S, Abu-Amer Y. The IKK inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis.
J. Biol. Chem. 279: 37219-37222 (2004).
*
-
Dai W, Gupta SL. Regulation of indoleamine 2,3-dioxygenase gene expression in human fibroblasts by interferon-gamma. Upstream control region discriminates between interferon-gamma and interferon-alpha.
J. Biol. Chem. 265: 19871-19877 (1990).
*
-
Dai X, Sayama K, Shirakata Y, Hanakawa Y, Yamasaki K, Tokumaru S, Yang L, Wang X, Hirakawa S, Tohyama M, Yamauchi T, Takashi K, Kagechika H, Hashimoto K. STAT5a/PPARgamma pathway regulates involucrin expression in keratinocyte differentiation.
J. Invest. Dermatol. 127: 1728-1735 (2007).
*
-
Dai X, Souza AT, Dai H, Lewis DL, Lee CK, Spencer AG, Herweijer H, Hagstrom JE, Linsley PS, Bassett DE, Ulrich RG, He YD. PPARalpha siRNA-treated expression profiles uncover the causal sufficiency network for compound-induced liver hypertrophy.
PLoS Comput. Biol. 3: e30 (2007).
*
-
Dai XG, Yao YM, Ai YH, Yu Y. The enhancing effect of "xuebijing injection" on lipopolysaccharide-induced apoptosis of regulatory T cells and mediation of polarization of helper T cells.
Zhonghua Shao Shang Za Zhi 25: 106-110 (2009).
-
Dai XY, Ou X, Hao XR, Cao DL, Tang YL, Hu YW, Li XX, Tang CK. The effect of T0901317 on ATP-binding cassette transporter A1 and Niemann-Pick type C1 in ApoE-/- mice.
J. Cardiovasc. Pharmacol. 51: 467-475 (2008).
-
Dai YD, Marrero IG, Gros P, Zaghouani H, Wicker LS, Sercarz EE. Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens.
Diabetes 58: 156-164 (2009).
*
-
Dairkee SH, Ji Y, Ben Y, Moore DH, Meng Z, Jeffrey SS. A molecular 'signature' of primary breast cancer cultures; patterns resembling tumor tissue.
BMC Genomics 5: 47 (2004).
*
-
Dajotoy T, Andersson P, Bjartell A, Lofdahl CG, Tapper H, Egesten A. Human eosinophils produce the T cell-attracting chemokines MIG and IP-10 upon stimulation with IFN-gamma.
J. Leukoc. Biol. 76: 685-691 (2004).
*
-
Dal-Ros S, Oswald-Mammosser M, Pestrikova T, Schott C, Boehm N, Bronner C, Chataigneau T, Geny B, Schini-Kerth VB. Losartan prevents portal hypertension induced, redox-mediated endothelial dysfunction in the mesenteric artery in rats.
Gastroenterology Oct 28 [Epub ahead of print] (2009).
*
-
Dalakas MC. Mechanisms of disease: signaling pathways and immunobiology of inflammatory myopathies.
Nat. Clin. Pract. Rheumatol. 2: 219-227 (2006).
*
-
Dalekos GN, Zachou K, Liaskos C, Gatselis N. Autoantibodies and defined target autoantigens in autoimmune hepatitis: an overview.
Eur. J. Intern. Med. 13: 293-303 (2002).
-
Dalmasso G, Charrier-Hisamuddin L, Thu Nguyen HT, Yan Y, Sitaraman S, Merlin D. PepT1-mediated tripeptide KPV uptake reduces intestinal inflammation.
Gastroenterology 134: 166-178 (2008).
*
-
Dalwadi H, Wei B, Schrage M, Spicher K, Su TT, Birnbaumer L, Rawlings DJ, Braun J. B cell developmental requirement for the Galphai2 gene.
J. Immunol. 170: 1707-1715 (2003).
*
-
Daly AC, Vizan P, Hill CS. SMAD3 protein levels are modulated by ras activity and during cell cycle to dictate TGF-beta responses.
J. Biol. Chem. Dec 26 [Epub ahead of print] (2009).
*
-
Daly AK. Significance of the minor cytochrome P450 3A isoforms.
Clin. Pharmacokinet. 45: 13-31 (2006).
-
Daly MJ, Rioux JD. New approaches to gene hunting in IBD.
Inflamm. Bowel Dis. 10: 312-317 (2004).
*
-
Dambacher J, Beigel F, Zitzmann K, de Toni E, Goke B, Diepolder HM, Auernhammer CJ, Brand S. The role of the novel Th17 cytokine IL-26 in intestinal inflammation.
Gut 58: 1207-1217 (2009).
*
-
Damiani D, Tiribelli M, Raspadori D, Michelutti A, Gozzetti A, Calistri E, Candoni A, Chiarvesio A, Lenoci M, Russo D, Fanin R. The role of MDR-related proteins in the prognosis of adult acute myeloid leukaemia (AML) with normal karyotype.
Hematol. Oncol. 25: 38-43 (2007).
-
Damiano F, Gnoni GV, Siculella L. Functional analysis of rat liver citrate carrier promoter: differential responsiveness to polyunsaturated fatty acids.
Biochem. J. 417: 561-571 (2009).
*
-
Dammeier J, Brauchle M, Falk W, Grotendorst GR, Werner S. Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?
Int. J. Biochem. Cell Biol. 30: 909-922 (1998).
*
-
Dammeyer P, Mwakigonja AR, Rethi B, Chiodi F, Wolpert EZ. Vaccination with beta-microglobulin-deficient dendritic cells protects against growth of beta-microglobulin-deficient tumours.
Scand. J. Immunol. 70: 44-52 (2009).
*
-
Damron FH, Qiu D, Yu HD. Pseudomonas aeruginosa sensor kinase KinB negatively controls alginate production through AlgW-dependent MucA proteolysis.
J. Bacteriol. 191: 2285-2295 (2009).
*
-
Damude HG, Zhang H, Farrall L, Ripp KG, Tomb JF, Hollerbach D, Yadav NS. Identification of bifunctional Delta12/omega3 fatty acid desaturases for improving the ratio of omega-3 to omega-6 fatty acids in microbes and plants.
Proc. Natl. Acad. Sci. U.S.A. 103: 9446-9451 (2006).
*
-
Danda RS, Habiba NM, Rincon-Choles H, Bhandari BK, Barnes JL, Abboud HE, Pergola PE. Kidney involvement in a nongenetic rat model of type 2 diabetes.
Kidney Int. 68: 2562-2571 (2005).
*
-
Dandrieux JR, Bornand VF, Doherr MG, Kano R, Zurbriggen A, Burgener IA. Evaluation of lymphocyte apoptosis in dogs with inflammatory bowel disease.
Am. J. Vet. Res. 69: 1279-1285 (2008).
-
Danese S, Sans M, de la Motte C, Graziani C, West G, Phillips MH, Pola R, Rutella S, Willis J, Gasbarrini A, Fiocchi C. Angiogenesis as a novel component of inflammatory bowel disease pathogenesis.
Gastroenterology 130: 2060-2073 (2006).
*
-
Danese S, Sans M, Scaldaferri F, Sgambato A, Rutella S, Cittadini A, Pique JM, Panes J, Katz JA, Gasbarrini A, Fiocchi C. TNF-alpha blockade down-regulates the CD40/CD40L pathway in the mucosal microcirculation: a novel anti-inflammatory mechanism of infliximab in Crohn's disease.
J. Immunol. 176: 2617-2624 (2006).
*
-
Danese S, Sgambato A, Papa A, Scaldaferri F, Pola R, Sans M, Lovecchio M, Gasbarrini G, Cittadini A, Gasbarrini A. Homocysteine triggers mucosal microvascular activation in inflammatory bowel disease.
Am. J. Gastroenterol. 100: 886-895 (2005).
*
-
Danesi F, Philpott M, Huebner C, Bordoni A, Ferguson LR. Food-derived bioactives as potential regulators of the IL-12/IL-23 pathway implicated in inflammatory bowel diseases.
Mutat. Res. Jan 9 [Epub ahead of print] (2010).
-
Dang CT, Shapiro CL, Hudis CA. Potential role of selective COX-2 inhibitors in cancer management.
Oncology (Huntingt.) 16: 30-36 (2002).
-
Dang H, Liu Y, Pang W, Wang N, Shyy JY, Zhu Y. Suppression of 2,3-oxidosqualene cyclase by high-fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile.
J. Biol. Chem. 284: 6218-6226 (2009).
*
-
Dang I, Nelson JK, DeVries GH. c-Kit receptor expression in normal human Schwann cells and Schwann cell lines derived from neurofibromatosis type 1 tumors.
J. Neurosci. Res. 82: 465-471 (2005).
*
-
Daniels G. The molecular genetics of blood group polymorphism.
Hum. Genet. Aug 29 [Epub ahead of print] (2009).
*
-
Daniels G. The molecular genetics of blood group polymorphism.
Transpl. Immunol. 14: 143-153 (2005).
-
Daniels I, Cavill D, Murray IA, Long RG. Elevated expression of iNOS mRNA and protein in coeliac disease.
Clin. Chim. Acta 356: 134-142 (2005).
*
-
Danis VA, Millington M, Hyland V, Lawford R, Huang Q, Grennan D. Increased frequency of the uncommon allele of a tumour necrosis factor alpha gene polymorphism in rheumatoid arthritis and systemic lupus erythematosus.
Dis. Markers. 12: 127-133 (1995).
-
Dankort D, Curley DP, Cartlidge RA, Nelson B, Karnezis AN, Damsky Jr WE, You MJ, Depinho RA, McMahon M, Bosenberg M. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.
Nat. Genet. 41: 544-552 (2009).
*
-
Dann CT, Alvarado AL, Molyneux LA, Denard BS, Garbers DL, Porteus MH. Spermatogonial stem cell self renewal requires OCT4, a factor down-regulated during retinoic acid induced differentiation.
Stem Cells 26: 2928-2937 (2008).
*
-
Darimont C, Avanti O, Zbinden I, Leone-Vautravers P, Mansourian R, Giusti V, Mace K. Liver X receptor preferentially activates de novo lipogenesis in human preadipocytes.
Biochimie 88: 309-318 (2006).
-
Darragh J, Hunter M, Pohler E, Nelson L, Dillon JF, Nenutil R, Vojtesek B, Ross PE, Kernohan N, Hupp TR. The calcium-binding domain of the stress protein SEP53 is required for survival in response to deoxycholic acid-mediated injury.
FEBS J. 273: 1930-1947 (2006).
*
-
Darsigny M, Babeu JP, Dupuis AA, Furth EE, Seidman EG, Levy E, Verdu EF, Gendron FP, Boudreau F. Loss of hepatocyte-nuclear-factor-4alpha affects colonic ion transport and causes chronic inflammation resembling inflammatory bowel disease in mice.
PLoS One 4: e7609 (2009).
*
-
Darwiche N, Celli G, Tennenbaum T, Glick AB, Yuspa SH, De Luca LM. Mouse skin tumor progression results in differential expression of retinoic acid and retinoid X receptors.
Cancer Res. 55: 2774-2782 (1995).
*
-
Darwish H, DeLuca HF. Vitamin D-regulated gene expression.
Crit. Rev. Eukaryot. Gene Expr. 3: 89-116 (1993).
-
Das A, Guyton MK, Matzelle DD, Ray SK, Banik NL. Time-dependent increases in protease activities for neuronal apoptosis in spinal cords of Lewis rats during development of acute experimental autoimmune encephalomyelitis.
J. Neurosci. Res. 86: 2992-3001 (2008).
-
Das J, Ren G, Zhang L, Roberts AI, Zhao X, Bothwell AL, Van Kaer L, Shi Y, Das G. Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation.
J. Exp. Med. 206: 2407-2416 (2009).
*
-
Das KK, Bajpai M, Kong Y, Liu J, Geng X, Das KM. Mesalamine suppresses the expression of a novel tropomyosin isoform, TC22, associated with colonic neoplasia.
Mol. Pharmacol. 76: 183-191 (2009).
*
-
Das KM. Immunopathogenesis of primary sclerosing cholangitis: possible role of a shared colonic and biliary epithelial antigen.
J. Gastroenterol. Hepatol. 19: S290-S294 (2004). *
-
Das KM, Bajpai M. Tropomyosins in human diseases: ulcerative colitis.
Adv. Exp. Med. Biol. 644: 158-167 (2008).
-
Das P, Abraham R, David C. HLA transgenic mice as models of human autoimmune diseases.
Rev. Immunogenet. 2: 105-114 (2000).
-
Das R, Dhokalia A, Huang XZ, Hammamieh R, Chakraborty N, Lindler LE, Jett M. Study of proinflammatory responses induced by Yersinia pestis in human monocytes using cDNA arrays.
Genes Immun. 8: 308-319 (2007).
*
-
Das S, Haddadi A, Veniamin S, Samuel J. Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34(+) progenitor-derived dendritic cells.
J. Biomed. Mater. Res. A. 85: 983-992 (2008).
*
-
Das S, Nwachukwu JC, Li D, Vulin AI, Martinez-Caballero S, Kinnally KW, Samuels HH. The nuclear receptor interacting factor-3 transcriptional coregulator mediates rapid apoptosis in breast cancer cells through direct and bystander-mediated events.
Cancer Res. 67: 1775-1782 (2007).
*
-
Das Sarma J, Ciric B, Marek R, Sadhukhan S, Caruso ML, Shafagh J, Fitzgerald DC, Shindler KS, Rostami AM. Functional interleukin-17 receptor A is expressed in central nervous system glia and upregulated in experimental autoimmune encephalomyelitis.
J. Neuroinflammation 6: 14 (2009).
-
Das SK, Chakrabarti R. Role of PPAR in cardiovascular diseases.
Recent Patents Cardiovasc. Drug Discov. 1: 193-209 (2006).
-
Das SK, Chu W, Zhang Z, Hasstedt SJ, Elbein SC. Calsquestrin 1 (CASQ1) gene polymorphisms under chromosome 1q21 linkage peak are associated with type 2 diabetes in Northern European Caucasians.
Diabetes 53: 3300-3306 (2004).
*
-
Das UN. Pathophysiology of metabolic syndrome X and its links to the perinatal period.
Nutrition 21: 762-773 (2005).
*
-
Das UN. A defect in the activity of Delta(6) and Delta(5) desaturases may be a factor predisposing to the development of insulin resistance syndrome.
Prostaglandins Leukot. Essent. Fatty Acids 72: 343-350 (2005).
*
-
Das UN. Perinatal supplementation of long-chain polyunsaturated fatty acids, immune response and adult diseases.
Med. Sci. Monit. 10: HY19-HY25 (2004).
*
-
Das UN. Insulin in the critically ill with focus on cytokines, reactive oxygen species, HLA-DR expression.
J. Assoc. Physicians India 55: S56-S65 (2007).
-
Das UN. A defect in the activity of Delta(6) and Delta(5) desaturases may be a factor in the initiation and progression of atherosclerosis.
Prostaglandins Leukot. Essent. Fatty Acids 76: 251-268 (2007).
*
-
Das UN. Folic acid and polyunsaturated fatty acids improve cognitive function and prevent depression, dementia, and Alzheimer's disease - but how and why?
Prostaglandins Leukot. Essent. Fatty Acids 78: 11-19 (2008).
*
-
Das UN, Rao AA. Gene expression profile in obesity and type 2 diabetes mellitus.
Lipids Health Dis. 6: 35 (2007).
*
-
Dasgupta A, Das S, Sarkar PK. Thyroid hormone promotes glutathione synthesis in astrocytes by up regulation of glutamate cysteine ligase through differential stimulation of its catalytic and modulator subunit mRNAs.
Free Radic. Biol. Med. 42: 617-626 (2007).
-
Dasgupta S, Bandopadhyay M, Pahan K. Generation of functional blocking monoclonal antibodies against mouse interleukin-12 p40 homodimer and monomer.
Hybridoma (Larchmt.) 27: 141-151 (2008).
-
Dasgupta S, Silva J, Wang G, Yu RK. Sulfoglucuronosyl paragloboside is a ligand for T cell adhesion: regulation of sulfoglucuronosyl paragloboside expression via nuclear factor kappaB signaling.
J. Neurosci. Res. 87: 3591-3599 (2009).
-
Dashtsoodol N, Watarai H, Sakata S, Taniguchi M. Identification of CD4(-)CD8(-) double-negative natural killer T cell precursors in the thymus.
PLoS ONE 3: e3688 (2008).
*
-
Dassoulas K, Gazouli M, Rizos S, Theodoropoulos G, Christoni Z, Nikiteas N, Karakitsos P. Common polymorphisms in the vascular endothelial growth factor gene and colorectal cancer development, prognosis, and survival.
Mol. Carcinog. 48: 563-569 (2009).
*
-
Dastani Z, Pajukanta P, Marcil M, Rudzicz N, Ruel I, Bailey SD, Lee JC, Lemire M, Faith J, Platko J, Rioux J, Hudson TJ, Gaudet D, Engert JC, Genest J. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.
Eur. J. Hum. Genet. Oct 21 [Epub ahead of print] (2009).
-
Dat NT, Lee JH, Lee K, Hong YS, Kim YH, Lee JJ. Phenolic constituents of Amorpha fruticosa that inhibit NF-kappaB activation and related gene expression.
J. Nat. Prod. 71: 1696-1700 (2008).
*
-
Datta A, Sinha-Datta U, Kaur Dhillon N, Buch S, Nicot C. The HTLV-I p30 Interferes with TLR4 signaling and modulates the release of pro-and anti-inflammatory cytokines from human macrophages.
J. Biol. Chem. 281: 23414-23424 (2006).
*
-
Dauchy S, Dutheil F, Weaver RJ, Chassoux F, Daumas-Duport C, Couraud PO, Scherrmann JM, De Waziers I, Decleves X. ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.
J. Neurochem. 107: 1518-1528 (2008).
-
Dauchy S, Miller F, Couraud PO, Weaver RJ, Weksler B, Romero IA, Scherrmann JM, De Waziers I, Decleves X. Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.
Biochem. Pharmacol. 77: 897-909 (2009).
*
-
Dauncey MJ, White P, Burton KA, Katsumata M. Nutrition-hormone receptor-gene interactions: implications for development and disease.
Proc. Nutr. Soc. 60: 63-72 (2001).
-
Dave SS, Fu K, Wright GW, Lam LT, Kluin P, Boerma EJ, Greiner TC, Weisenburger DD, Rosenwald A, Ott G, Muller-Hermelink HK, Gascoyne RD, Delabie J, Rimsza LM, Braziel RM, Grogan TM, Campo E, Jaffe ES, Dave BJ, Sanger W, Bast M, Vose JM, Armitage JO, et al. Molecular diagnosis of Burkitt's lymphoma.
N. Engl. J. Med. 354: 2431-2442 (2006).
*
-
Dave VP, Kaul D, Sharma Y, Bhattacharya R. Functional genomics of blood cellular LXR-alpha gene in human coronary heart disease.
J. Mol. Cell. Cardiol. 46: 536-544 (2009).
-
Davey GM, Heath WR, Starr R. SOCS1: a potent and multifaceted regulator of cytokines and cell-mediated inflammation.
Tissue Antigens 67: 1-9 (2006).
*
-
Davey HW, Park SH, Grattan DR, McLachlan MJ, Waxman DJ. STAT5b-deficient mice are growth hormone pulse-resistant. Role of STAT5b in sex-specific liver p450 expression.
J. Biol. Chem. 274: 35331-35336 (1999).
*
-
Davey HW, Xie T, McLachlan MJ, Wilkins RJ, Waxman DJ, Grattan DR. STAT5b is required for GH-induced liver IGF-I gene expression.
Endocrinology 142: 3836-3841 (2001).
*
-
Davey JC, Nomikos AP, Wungjiranirun M, Sherman JR, Ingram L, Batki C, Lariviere JP, Hamilton JW. Arsenic as an endocrine disruptor: arsenic disrupts retinoic acid receptor-and thyroid hormone receptor-mediated gene regulation and thyroid hormone-mediated amphibian tail metamorphosis.
Environ. Health Perspect. 116: 165-172 (2008).
*
-
Davey MP, Martin TM, Planck SR, Lee J, Zamora D, Rosenbaum JT. Human endothelial cells express NOD2/CARD15 and increase IL-6 secretion in response to muramyl dipeptide.
Microvasc. Res. 71: 103-107 (2006).
*
-
Davezac N, Tondelier D, Lipecka J, Fanen P, Demaugre F, Debski J, Dadlez M, Schrattenholz A, Cahill MA, Edelman A. Global proteomic approach unmasks involvement of keratins 8 and 18 in the delivery of cystic fibrosis transmembrane conductance regulator (CFTR)/DeltaF508-CFTR to the plasma membrane.
Proteomics 4: 3833-3844 (2004).
*
-
David A, Fridlich R, Aviram I. The presence of membrane proteinase 3 in neutrophil lipid rafts and its colocalization with FcgammaRIIIb and cytochrome b558.
Exp. Cell Res. 308: 156-165 (2005).
*
-
David AL, Peebles DM, Gregory L, Waddington SN, Themis M, Weisz B, Ruthe A, Lawrence L, Cook T, Rodeck CH, Coutelle C. Clinically applicable procedure for gene delivery to fetal gut by ultrasound-guided gastric injection: toward prenatal prevention of early-onset intestinal diseases.
Hum. Gene Ther. 17: 767-779 (2006).
-
David G, Morvan M, Gagne K, Kerdudou N, Willem C, Devys A, Bonneville M, Follea G, Bignon JD, Retiere C. Discrimination between the main activating and inhibitory killer cell immunoglobulin-like receptor positive natural killer cell subsets using newly characterized monoclonal antibodies.
Immunology 128: 172-184 (2009).
*
-
David SP, Murthy NV, Rabiner EA, Munafo MR, Johnstone EC, Jacob R, Walton RT, Grasby PM. A functional genetic variation of the serotonin (5-HT) transporter affects 5-HT1A receptor binding in humans.
J. Neurosci. 25: 2586-2590 (2005).
*
-
Davidson AJ, Castanon-Cervantes O, Stephan FK. Daily oscillations in liver function: diurnal vs circadian rhythmicity.
Liver Int. 24: 179-186 (2004).
*
-
Davidson AL, Dassa E, Orelle C, Chen J. Structure, function, and evolution of bacterial ATP-binding cassette systems.
Microbiol. Mol. Biol. Rev. 72: 317-364 (2008).
*
-
Davidson DJ, Gray MA, Kilanowski FM, Tarran R, Randell SH, Sheppard DN, Argent BE, Dorin JR. Murine epithelial cells: isolation and culture.
J. Cyst. Fibros. 3 Suppl. 2: 59-62 (2004).
-
Davidson H, McLachlan G, Wilson A, Boyd AC, Doherty A, Macgregor G, Davies L, Painter HA, Coles R, Hyde SC, Gill DR, Amaral MD, Collie DD, Porteous DJ, Penque D. Human specific cystic fibrosis transmembrane conductance regulator antibodies detect in vivo gene transfer to ovine airways.
Am. J. Respir. Cell. Mol. Biol. 35: 72-83 (2006).
*
-
Davidson LA, Nguyen DV, Hokanson RM, Callaway ES, Isett RB, Turner ND, Dougherty ER, Wang N, Lupton JR, Carroll RJ, Chapkin RS. Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat.
Cancer Res. 64: 6797-6804 (2004).
*
-
Davidson LA, Wang N, Shah MS, Lupton JR, Ivanov I, Chapkin RS. n-3 Polyunsaturated fatty acids modulate carcinogen-directed non-coding microRNA signatures in rat colon.
Carcinogenesis 30: 2077-2084 (2009).
-
Davidson ME, Kerepesi LA, Soto A, Chan VT. D-Serine exposure resulted in gene expression changes implicated in neurodegenerative disorders and neuronal dysfunction in male Fischer 344 rats.
Arch. Toxicol. 83: 747-762 (2009).
*
-
Davidson TS, Longnecker DS, Hickey WF. An experimental model of autoimmune pancreatitis in the rat.
Am. J. Pathol. 166: 729-736 (2005).
*
-
Davidson-Moncada J, Papavasiliou FN, Tam W. MicroRNAs of the immune system.
Ann. N. Y. Acad. Sci. 1183: 183-194 (2010).
*
-
Davies BS, Waki H, Beigneux AP, Farber E, Weinstein MM, Wilpitz DC, Tai LJ, Evans RM, Fong LG, Tontonoz P, Young SG. The expression of GPIHBP1, an endothelial cell binding site for lipoprotein lipase and chylomicrons, is induced by PPARgamma.
Mol. Endocrinol. 22: 2496-2504 (2008).
*
-
Davies CJ. Why is the fetal allograft not rejected?
J. Anim. Sci. 85: E32-E35 (2007).
*
-
Davies GE, Locke SM, Wright PW, Li H, Hanson RJ, Miller JS, Anderson SK. Identification of bidirectional promoters in the human KIR genes.
Genes Immun. 8: 245-253 (2007).
*
-
Davies JM, Sheil B, Shanahan F. Bacterial signalling overrides cytokine signalling and modifies dendritic cell differentiation.
Immunology 128: e805-e815 (2009).
-
Davies JS, Kotokorpi P, Eccles SR, Barnes SK, Tokarczuk PF, Allen SK, Whitworth HS, Guschina IA, Evans BA, Mode A, Zigman JM, Wells T. Ghrelin induces abdominal obesity via GHS-R-dependent lipid retention.
Mol. Endocrinol. 23: 914-924 (2009).
*
-
Davies LA, Varathalingam A, Painter H, Lawton AE, Sumner-Jones SG, Nunez-Alonso GA, Chan M, Munkonge F, Alton EW, Hyde SC, Gill DR. Adenovirus-mediated in utero expression of CFTR does not improve survival of CFTR knockout mice.
Mol. Ther. 16: 812-818 (2008).
-
Davies MR, Ribeiro LR, Downey-Jones M, Needham MR, Oakley C, Wardale J. Ligands for retinoic acid receptors are elevated in osteoarthritis and may contribute to pathologic processes in the osteoarthritic joint.
Arthritis Rheum. 60: 1722-1732 (2009).
*
-
Davies PS, Enns CA. Expression of the hereditary hemochromatosis protein HFE increases ferritin levels by inhibiting iron export in HT29 cells.
J. Biol. Chem. 279: 25085-25092 (2004).
*
-
Davies R, Schuurman A, Barker CR, Clothier B, Chernova T, Higginson FM, Judah DJ, Dinsdale D, Edwards RE, Greaves P, Gant TW, Smith AG. Hepatic gene expression in protoporphyic fech mice is associated with cholestatic injury but not a marked depletion of the heme regulatory pool.
Am. J. Pathol. 166: 1041-1053 (2005).
*
-
Davies RJ, Scott IS, Morris LS, Rushbrook SM, Bird K, Vowler SL, Arends M, Miller R, Coleman N. Increased expression of minichromosome maintenance protein 2 in active inflammatory bowel disease.
Colorectal Dis. 6: 103-110 (2004).
-
Davila S, Hibberd ML, Hari Dass R, Wong HE, Sahiratmadja E, Bonnard C, Alisjahbana B, Szeszko JS, Balabanova Y, Drobniewski F, van Crevel R, van de Vosse E, Nejentsev S, Ottenhoff TH, Seielstad M. Genetic association and expression studies indicate a role of Toll-like receptor 8 in pulmonary tuberculosis.
PLoS Genet. 4: e1000218 (2008).
*
-
Davis AS, Vergne I, Master SS, Kyei GB, Chua J, Deretic V. Mechanism of inducible nitric oxide synthase exclusion from mycobacterial phagosomes.
PLoS Pathog. 3: e186 (2007).
*
-
Davis PB, Cooper MJ. Vectors for airway gene delivery.
AAPS J. 9: E11-E17 (2007).
*
-
Davis RS. Fc receptor-like molecules.
Annu. Rev. Immunol. 25: 525-560 (2007).
*
-
Davis W Jr, Boyd JT, Ile KE, Tew KD. Human ATP-binding cassette transporter-2 (ABCA2) positively regulates low-density lipoprotein receptor expression and negatively regulates cholesterol esterification in Chinese hamster ovary cells.
Biochim. Biophys. Acta 1683: 89-100 (2004).
*
-
Davoodi-Semiromi A, Samson N, Daniell H. The green vaccine: a global strategy to combat infectious and autoimmune diseases.
Hum. Vaccin. 5: 488-493 (2009).
-
Daw EW, Yu R. The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees.
BMC Proc. 1 Suppl. 1: S108 (2007).
*
-
Dawczynski C, Schubert R, Hein G, Muller A, Eidner T, Vogelsang H, Basu S, Jahreis G. Long-term moderate intervention with n-3 long-chain PUFA-supplemented dairy products: effects on pathophysiological biomarkers in patients with rheumatoid arthritis.
Br. J. Nutr. 101: 1517-1526 (2009).
*
-
Dawson H, Solano-Aguilar G, Beal M, Beshah E, Vangimalla V, Jones E, Botero S, Urban JF Jr. Localized Th1-, Th2-, Treg and inflammation-associated hepatic and pulmonary immune responses in Ascaris-infected swine are increased by retinoic acid.
Infect. Immun. 77: 2576-2587 (2009).
*
-
Dawson PA. Molecular pathways for intestinal bile acid transport.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 53. June 18-19 (2004). *
-
Dawson PA, Rao A, Craddock AL, Haywood J. Analysis of the molecular mechanisms responsible for intestinal basolateral bile acid transport.
Falk Symposium 155. XIII FALK LIVER WEEK (Part I) XIX International Bile Acid Meeting. Bile Acids: Biological Actions and Clinical Relevance, October 6 - 7, 2006 Freiburg (Germany), p. 43 (2006). *
-
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, Depierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression.
Nature 443: 350-354 (2006).
*
-
Day MJ. Canine sino-nasal aspergillosis: parallels with human disease.
Med. Mycol. 47 Suppl. 1: S315-S323 (2009).
*
-
Dayer Schneider J, Seibold I, Saxer-Sekulic N, Paredes BE, Saurer L, Mueller C. Lack of TNFR2 expression by CD4(+) T cells exacerbates experimental colitis.
Eur. J. Immunol. 39: 1743-1753 (2009).
*
-
de Alencar BC, Persechini PM, Haolla FA, de Oliveira G, Silverio JC, Lannes-Vieira J, Machado AV, Gazzinelli RT, Bruna-Romero O, Rodrigues MM. Perforin and gamma interferon expression are required for CD4+ and CD8+ T-cell-dependent protective immunity against a human parasite, Trypanosoma cruzi, elicited by heterologous plasmid DNA prime-recombinant adenovirus 5 boost vaccination.
Infect. Immun. 77: 4383-4395 (2009).
*
-
de Almeida AC, Barbosa SM, Barjas-Castro Mde L, Olalla-Saad ST, Condino-Neto A. The role of glucocorticoid in SIRP alpha and SHP-1 gene expression in AIHA patients.
Immunopharmacol. Immunotoxicol. 31: 636-640 (2009).
-
de Almeida AC, Barbosa SM, Lourdes Barjas-Castro MD, Olalla-Saad ST, Condino-Neto A. The role of glucocorticoid in SIRPalpha and SHP-1 gene expression in AIHA patients.
Immunopharmacol. Immunotoxicol. May 20 [Epub ahead of print] (2009).
-
De Arce M, O'Brien S, Hegarty J, O'Mahoney SM, Cashman SM, Martinez A, Delgado M, FitzGerald MX. Deletion delta F508 and clinical expression of cystic fibrosis-related liver disease.
Clin. Genet. 42: 271-272 (1992).
-
De Backer O, Elinck E, Priem E, Leybaert L, Lefebvre RA. PPARgamma activation alleviates postoperative ileus in mice by inhibition of Egr-1 expression and its downstream target genes.
J. Pharmacol. Exp. Ther. 331: 496-503 (2009).
*
-
de Bie P, van de Sluis B, Burstein E, van de Berghe PV, Muller P, Berger R, Gitlin JD, Wijmenga C, Klomp LW. Distinct Wilson's disease mutations in ATP7B are associated with enhanced binding to COMMD1 and reduced stability of ATP7B.
Gastroenterology 133: 1316-1326 (2007).
*
-
de Borst M, Prakash J, Sandovici M, Klok PA, Hamming I, Kok RJ, Navis G, van Goor H. c-Jun N-terminal kinase is crucially involved in renal tubulo-interstitial inflammation.
J. Pharmacol. Exp. Ther. 331: 896-905 (2009).
*
-
De Bosscher K, Vanden Berghe W, Beck IM, Van Molle W, Hennuyer N, Hapgood J, Libert C, Staels B, Louw A, Haegeman G. A fully dissociated compound of plant origin for inflammatory gene repression.
Proc. Natl. Acad. Sci. U.S.A. 102: 15827-15832 (2005).
*
-
De Bosscher K, Vanden Berghe W, Haegeman G. Cross-talk between nuclear receptors and nuclear factor kappaB.
Oncogene 25: 6868-6886 (2006).
*
-
de Bruin EC, van de Pas S, van de Velde CJ, van Krieken JH, Peltenburg LT, Marijnen CA, Medema JP. Gene expression profiling reveals two separate mechanisms regulating apoptosis in rectal carcinomas in vivo.
Apoptosis 12: 1671-1680 (2007).
*
-
de Buhr MF, Hedrich HJ, Westendorf AM, Obermeier F, Hofmann C, Zschemisch NH, Buer J, Bumann D, Goyert SM, Bleich A. Analysis of Cd14 as a genetic modifier of experimental inflammatory bowel disease (IBD) in mice.
Inflamm. Bowel Dis. 15: 1824-1836 (2009).
*
-
de Buhr MF, Mahler M, Geffers R, Hansen W, Westendorf AM, Lauber J, Buer J, Schlegelberger B, Hedrich HJ, Bleich A. Cd14, Gbp1, and Pla2g2a: three major candidate genes for experimental IBD identified by combining QTL and microarray analyses.
Physiol. Genomics 25: 426-434 (2006).
*
-
De Caterina R, Cybulsky MA, Clinton SK, Gimbrone MA Jr, Libby P. Omega-3 fatty acids and endothelial leukocyte adhesion molecules.
Prostaglandins Leukot. Essent. Fatty Acids 52: 191-195 (1995).
-
De Caterina R, Cybulsky MI, Clinton SK, Gimbrone MA Jr, Libby P. The omega-3 fatty acid docosahexaenoate reduces cytokine-induced expression of proatherogenic and proinflammatory proteins in human endothelial cells.
Arterioscler. Thromb. 14: 1829-1836 (1994).
-
De Caterina R, Liao JK, Libby P. Fatty acid modulation of endothelial activation.
Am. J. Clin. Nutr. 71: 213S-223S (2000).
*
-
De Caterina R, Massaro M. Omega-3 fatty acids and the regulation of expression of endothelial pro-atherogenic and pro-inflammatory genes.
J. Membr. Biol. 206: 103-116 (2005).
*
-
de Cid R, Riveira-Munoz E, Zeeuwen PL, Robarge J, Liao W, Dannhauser EN, Giardina E, Stuart PE, Nair R, Helms C, Escaramís G, Ballana E, Martín-Ezquerra G, Heijer MD, Kamsteeg M, Joosten I, Eichler EE, Lázaro C, Pujol RM, Armengol L, et al. Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis.
Nat. Genet. 41: 211-215 (2009).
*
-
De Fabiani E, Mitro N, Anzulovich AC, Pinelli A, Galli G, Crestani M. The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis…
J. Biol. Chem. 276: 30708-30716 (2001).
*
-
De Fabiani E, Mitro N, Gilardi F, Caruso D, Galli G, Crestani M. Coordinated control of cholesterol catabolism to bile acids and of gluconeogenesis via a novel mechanism of transcription regulation linked to the fasted-to-fed cycle.
J. Biol. Chem. 278: 39124-39132 (2003).
*
-
de Fraia Pinto L, Compri CM, Fornari JV, Bartchewsky W, Cintra DE, Trevisan M, de Oliveira Carvalho P, Ribeiro ML, Velloso LA, Saad MJ, Pedrazzoli J Jr, Gambero A. The immunosuppressant drug, thalidomide, improves hepatic alterations induced by a high-fat diet in mice.
Liver Int. Jan 15 [Epub ahead of print] (2010).
*
-
De Gobbi M, Viprakasit V, Hughes JR, Fisher C, Buckle VJ, Ayyub H, Gibbons RJ, Vernimmen D, Yoshinaga Y, de Jong P, Cheng JF, Rubin EM, Wood WG, Bowden D, Higgs DR. A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter.
Science 312: 1215-1217 (2006).
*
-
De Gottardi A, Hadengue A, Dumonceau JM. Retinoids, bile acids and PPARs in Barrett's oesophagus.
Gut 57: 137 (2008).
*
-
De Gottardi A, Pazienza V, Pugnale P, Bruttin F, Rubbia-Brandt L, Juge-Aubry CE, Meier CA, Hadengue A, Negro F. Peroxisome proliferator-activated receptor-alpha and -gamma mRNA levels are reduced in chronic hepatitis C with steatosis and genotype 3 infection.
Aliment. Pharmacol.Ther. 23: 107-114 (2006).
*
-
De Gottardi A, Touri F, Maurer CA, Perez A, Maurhofer O, Ventre G, Bentzen CL, Niesor EJ, Dufour JF. The bile acid nuclear receptor FXR and the bile acid binding protein IBABP are differently expressed in colon cancer.
Dig. Dis. Sci. 49: 982-989 (2004).
*
-
De Gottardi A, Vinciguerra M, Sgroi A, Moukil M, Ravier-Dall'Antonia F, Pazienza V, Pugnale P, Foti M, Hadengue A. Microarray analyses and molecular profiling of steatosis induction in immortalized human hepatocytes.
Lab. Invest. 87: 792-806 (2007).
*
-
de Groot M, Teunissen MB, Ortonne JP, Lambert JR, Naeyaert JM, Picavet DI, Arreaza MG, Simon JS, Kraan M, Bos JD, de Rie MA. Expression of the chemokine receptor CCR5 in psoriasis and results of a randomized placebo controlled trial with a CCR5 inhibitor.
Arch. Dermatol. Res. 299: 305-313 (2007).
*
-
de Haan W, de Vries-van der Weij J, Mol IM, Hoekstra M, A Romijn J, Jukema JW, Havekes LM, Princen HM, Rensen PC. PXR agonism decreases plasma HDL levels in apoE3-Leiden.CETP mice.
Biochim. Biophys. Acta 1791: 191-197 (2009).
*
-
de Heredia FP, Sanchez J, Priego T, Larque E, Del Puy Portillo M, Palou A, Zamora S, Garaulet M. Adiponectin is associated with serum and adipose tissue fatty acid composition in rats.
J. Endocrinol. Invest. 32: 659-665 (2009).
-
De Jager PL, Baecher-Allan C, Maier LM, Arthur AT, Ottoboni L, Barcellos L, McCauley JL, Sawcer S, Goris A, Saarela J, Yelensky R, Price A, Leppa V, Patterson N, de Bakker PI, Tran D, Aubin C, Pobywajlo S, Rossin E, et al. The role of the CD58 locus in multiple sclerosis.
Proc. Natl. Acad. Sci. U.S.A. 106: 5264-5269 (2009).
*
-
De Jager PL, Jia X, Wang J, de Bakker PI, Ottoboni L, Aggarwal NT, Piccio L, Raychaudhuri S, Tran D, Aubin C, Briskin R, Romano S; International MS Genetics Consortium, Baranzini SE, McCauley JL, Pericak-Vance MA, Haines JL, Gibson RA, Naeglin Y, et al. Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci.
Nat. Genet. 41: 776-782 (2009).
*
-
de Jersey J, Snelgrove SL, Palmer SE, Teteris SA, Mullbacher A, Miller JF, Slattery RM. beta Cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice.
Proc. Natl. Acad. Sci. U.S.A. 104: 1295-1300 (2007).
*
-
De Jesus M, Nicola AM, Frases S, Lee IR, Mieses S, Casadevall A. Galactoxylomannan-mediated immunological paralysis results from specific B cell depletion in the context of widespread immune system damage.
J. Immunol. 183: 3885-3894 (2009).
-
de Jong-Curtain TA, Parslow AC, Trotter AJ, Hall NE, Verkade H, Tabone T, Christie EL, Crowhurst MO, Layton JE, Shepherd IT, Nixon SJ, Parton RG, Zon LI, Stainier DY, Lieschke GJ, Heath JK. Abnormal nuclear pore formation triggers apoptosis in the intestinal epithelium of elys-deficient zebra fish.
Gastroenterology 136: 902-911.e7 (2009).
*
-
de Jonge HR. Cystic fibrosis mice rehabilitated for studies of airway gland dysfunction.
J. Physiol. 580: 7-8 (2007).
*
-
de la Fontaine L, Schwarz M, Plischke H, Kleindienst N, Gruber R. Lack of association of the CD14/C-159T polymorphism with susceptibility and serological activity parameters of rheumatoid arthritis.
Scand. J. Rheumatol. 35: 20-22 (2006).
*
-
de la Monte SM, Tong M, Lester-Coll N, Plater M Jr, Wands JR. Therapeutic rescue of neurodegeneration in experimental type 3 diabetes: relevance to Alzheimer's disease.
J. Alzheimers Dis. 10: 89-109 (2006).
-
de la Paz Bettinotti M, Kolek A, Brunnler G, Haas P, Paul C, Hochberger M, Bartova A, Kimura A, Sasazuki T, Albert ED. Polymorphism of the 5' flanking region of the HLA-DQA1 gene in coeliac disease.
Eur. J. Immunogenet. 20: 399-407 (1993).
-
De Lerma Barbaro A, De Ambrosis A, Banelli B, Pira GL, Aresu O, Romani M, Ferrini S, Accolla RS. Methylation of CIITA promoter IV causes loss of HLA-II inducibility by IFN-gamma in promyelocytic cells.
Int. Immunol. 20: 1457-1466 (2008).
*
-
De Lisle RC. Altered transit and bacterial overgrowth in the cystic fibrosis mouse small intestine.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G104-G111 (2007).
*
-
De Lisle RC, Meldi L, Flynn M, Jansson K. Altered eicosanoid metabolism in the cystic fibrosis mouse small intestine.
J. Pediatr. Gastroenterol. Nutr. 47: 406-416 (2008).
*
-
De Lisle RC, Petitt M, Huff J, Isom KS, Agbas A. MUCLIN expression in the cystic fibrosis transmembrane conductance regulator knockout mouse.
Gastroenterology 113: 521-532 (1997).
*
-
De Lisle RC, Roach EA, Norkina O. Eradication of small intestinal bacterial overgrowth in the cystic fibrosis mouse reduces mucus accumulation.
J. Pediatr. Gastroenterol. Nutr. 42: 46-52 (2006).
*
-
de Lisle RC, Sewell R, Meldi L. Enteric circular muscle dysfunction in the cystic fibrosis mouse small intestine.
Neurogastroenterol. Motil. Oct 8 [Epub ahead of print] (2009).
-
De Luca V, Likhodi O, Kennedy JL, Wong AH. Differential expression and parent-of-origin effect of the 5-HT2A receptor gene C102T polymorphism: analysis of suicidality in schizophrenia and bipolar disorder.
Am. J. Med. Genet. B. Neuropsychiatr. Genet. 144B: 370-374 (2007).
-
De Marchis ML, Ballarino M, Salvatori B, Puzzolo MC, Bozzoni I, Fatica A. A new molecular network comprising PU.1, interferon regulatory factor proteins and miR-342 stimulates ATRA-mediated granulocytic differentiation of acute promyelocytic leukemia cells.
Leukemia 23: 856-862 (2009).
-
de Messias-Reason IJ, Boldt AB, Moraes Braga AC, Von Rosen Seeling Stahlke E, Dornelles L, Pereira-Ferrari L, Kremsner PG, Kun JF. The association between mannan-binding lectin gene polymorphism and clinical leprosy: new insight into an old paradigm.
J. Infect. Dis. 196: 1379-1385 (2007).
*
-
De Minicis S, Candelaresi C, Marzioni M, Saccomano S, Roskams T, Casini A, Risaliti A, Salzano R, Cautero N, di Francesco F, Benedetti A, Svegliati-Baroni G. Role of endogenous opioids in modulating HSC activity in vitro and liver fibrosis in vivo.
Gut 57: 352-364 (2008).
-
De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells.
Hepatology 48: 2016-2026 (2008).
*
-
de Miranda NF, Nielsen M, Pereira D, van Puijenbroek M, Vasen HF, Hes FJ, van Wezel T, Morreau H. MUTYH-associated polyposis carcinomas frequently lose HLA class I expression - a common event amongst DNA-repair-deficient colorectal cancers.
J. Pathol. 219: 69-76 (2009).
*
-
de Nigris F, Williams-Ignarro S, Lerman LO, Crimi E, Botti C, Mansueto G, D'Armiento FP, De Rosa G, Sica V, Ignarro LJ, Napoli C. Beneficial effects of pomegranate juice on oxidation-sensitive genes and endothelial nitric oxide synthase activity at sites of perturbed shear stress.
Proc. Natl. Acad. Sci. U.S.A. 102: 4896-4901 (2005).
*
-
De Nitto D, Monteleone I, Franze E, Pallone F, Monteleone G. Involvement of interleukin-15 and interleukin-21, two gamma-chain-related cytokines, in celiac disease.
World J. Gastroenterol. 15: 4609-4614 (2009).
*
-
de Oliveira CP, Stefano JT, de Lima VM, de Sa SV, Simplicio FI, de Mello ES, Correa-Giannella ML, Alves VA, Laurindo FR, de Oliveira MG, Giannella-Neto D, Carrilho FJ. Hepatic gene expression profile associated with non-alcoholic steatohepatitis protection by S-nitroso-N-acetylcysteine in ob/ob mice.
J. Hepatol. 45: 725-733 (2006).
*
-
de Pablo MA, Alvarez de Cienfuegos G. Modulatory effects of dietary lipids on immune system functions.
Immunol. Cell Biol. 78: 31-39 (2000).
*
-
De Paiva CS, Chotikavanich S, Pangelinan SB, Pitcher JD 3rd, Fang B, Zheng X, Ma P, Farley WJ, Siemasko KF, Niederkorn JY, Stern ME, Li DQ, Pflugfelder SC. IL-17 disrupts corneal barrier following desiccating stress.
Mucosal Immunol. 2: 243-253 (2009).
-
De Palma C, Falcone S, Panzeri C, Radice S, Bassi MT, Clementi E. Endothelial nitric oxide synthase overexpression by neuronal cells in neurodegeneration: a link between inflammation and neuroprotection.
J. Neurochem. 106: 193-204 (2008).
*
-
De Palma G, Cinova J, Stepankova R, Tuckova L, Sanz Y. Pivotal advance: Bifidobacteria and Gram-negative bacteria differentially influence immune responses in the proinflammatory milieu of celiac disease.
J. Leukoc. Biol. Dec 14 [Epub ahead of print] (2009).
*
-
De Pascale MC, Bassi AM, Patrone V, Villacorta L, Azzi A, Zingg JM. Increased expression of transglutaminase-1 and PPARgamma after vitamin E treatment in human keratinocytes.
Arch. Biochem. Biophys. 447: 97-106 (2006).
*
-
De Re V, Simula MP, Caggiari L, Orzes N, Spina M, Da Ponte A, De Appollonia L, Dolcetti R, Canzonieri V, Cannizzaro R. Proteins specifically hyperexpressed in a coeliac disease patient with aberrant T cells.
Clin. Exp. Immunol. 148: 402-409 (2007).
*
-
De Re V, Simula MP, Cannizzaro R, Pavan A, De Zorzi MA, Toffoli G, Canzonieri V. Galectin-10, eosinophils, and celiac disease.
Ann. N. Y. Acad. Sci. 1173: 357-364 (2009).
*
-
de Rijke B, van Horssen-Zoetbrood A, Veenbergen S, Fredrix H, de Witte T, van de Wiel-van Kemenade E, Dolstra H. Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens.
J. Immunol. Methods 329: 125-137 (2008).
*
-
de Sa AR, Moreira PR, Xavier GM, Sampaio I, Kalapothakis E, Dutra WO, Gomez RS. Association of CD14, IL1B, IL6, IL10 and TNFA functional gene polymorphisms with symptomatic dental abscesses.
Int. Endod. J. 40: 563-572 (2007).
-
De Silva MG, Hildebrand MS, Christopoulos H, Newman MR, Bell K, Ritchie M, Smyth GK, Dahl HH. Gene expression changes during step-wise differentiation of embryonic stem cells along the inner ear hair cell pathway.
Acta Otolaryngol. 126: 1148-1157 (2006).
*
-
De Stefano D, De Rosa G, Maiuri MC, Ungaro F, Quaglia F, Iuvone T, Cinelli MP, La Rotonda MI, Carnuccio R. Oligonucleotide decoy to NF-kappaB slowly released from PLGA microspheres reduces chronic inflammation in rat.
Pharmacol. Res. 60: 33-40 (2009).
*
-
De Stefano D, Maiuri MC, Iovine B, Ialenti A, Bevilacqua MA, Carnuccio R. The role of NF-kappaB, IRF-1, and STAT-1alpha transcription factors in the iNOS gene induction by gliadin and IFN-gamma in RAW 264.7 macrophages.
J. Mol. Med. 84: 65-74 (2006).
*
-
De Stefano D, Maiuri MC, Simeon V, Grassia G, Soscia A, Cinelli MP, Carnuccio R. Lycopene, quercetin and tyrosol prevent macrophage activation induced by gliadin and IFN-gamma.
Eur. J. Pharmacol. 566: 192-199 (2007).
*
-
de Villiers JN, Treurnicht FK, Warnich L, Carr J, van Rensburg SJ, Kotze MJ. Analysis of viral and genetic factors in South African patients with multiple sclerosis.
Metab. Brain Dis. 21: 163-169 (2006).
*
-
De Vincenzi M, Vincentini O, Di Nardo G, Boirivant M, Gazza L, Pogna N. Two prolamin peptides from durum wheat preclude celiac disease-specific T cell activation by gluten proteins.
Eur. J. Nutr. Nov 6 [Epub ahead of print] (2009).
*
-
De Vita S, Quartuccio L, Fabris M. Hepatitis C virus infection, mixed crioglobulinemia cryoglobulinemia and BLyS upregulation: targeting the infectious trigger, the autoimmune response, or both?
Autoimmun. Rev. 8: 95-99 (2008).
-
de Vogel-van den Bosch HM, Bunger M, de Groot PJ, Bosch-Vermeulen H, Hooiveld GJ, Muller M. PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression.
BMC Genomics 9: 231 (2008).
*
-
De Vos M. Joint involvement associated with inflammatory bowel disease.
Dig. Dis. 27: 511-515 (2009).
-
de Vries B, Kohl J, Leclercq WK, Wolfs TG, van Bijnen AA, Heeringa P, Buurman WA. Complement factor C5a mediates renal ischemia-reperfusion injury independent from neutrophils.
J. Immunol. 170: 3883-3889 (2003).
*
-
de Vries HS, Plantinga TS, van Krieken JH, Stienstra R, van Bodegraven AA, Festen EA, Weersma RK, Crusius JB, Linskens RK, Joosten LA, Netea MG, de Jong DJ. Genetic association analysis of the functional c.714T>G polymorphism and mucosal expression of dectin-1 in inflammatory bowel disease.
PLoS One 4: e7818 (2009).
*
-
De Wit M, Keil D, Remmerie N, Ven KV, Brandhof EJ, Knapen D, Witters E, Coen WD. Molecular targets of TBBPA in zebrafish analysed through integration of genomic and proteomic approaches.
Chemosphere 74: 96-105 (2008).
*
-
de Wit NJ, Bosch-Vermeulen H, de Groot PJ, Hooiveld GJ, Grootte Bromhaar MM, Jansen J, Muller M, van der Meer R. The role of the small intestine in the development of dietary fat-induced obesity and insulin resistance in C57BL/6J mice.
BMC Med. Genomics 1: 14 (2008).
*
-
de Zoeten EF, Hancock WW. Strategies to cure experimental autoimmune colitis using antigen-specific Foxp3(+) regulatory T cells.
Gastroenterology 134: 2171-2174 (2008).
*
-
de Zoeten EF, Lee I, Wang L, Chen C, Ge G, Wells AD, Hancock WW, Ozkaynak E. Foxp3 processing by proprotein convertases and control of regulatory T cell function.
J. Biol. Chem. 284: 5709-5716 (2009).
*
-
de Zoeten EF, Wang L, Sai H, Dillmann WH, Hancock WW. Expression of HDAC9 by T regulatory cells prevents colitis in mice.
Gastroenterology 138: 583-594 (2010).
*
-
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M, Kuchroo VK, Strom TB, Robson SC. Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression.
J. Exp. Med. 204: 1257-1265 (2007).
*
-
Deakin S, Guernier S, James RW. Pharmacogenetic interaction between paraoxonase-1 gene promoter polymorphism C-107T and statin.
Pharmacogenet. Genomics 17: 451-457 (2007).
-
Dealberto MJ. Why are immigrants at increased risk for psychosis? Vitamin D insufficiency, epigenetic mechanisms, or both?
Med. Hypotheses 68: 259-267 (2007).
-
Dean EJ, Ranson M, Blackhall F, Dive C. X-linked inhibitor of apoptosis protein as a therapeutic target.
Expert Opin. Ther. Targets 11: 1459-1471 (2007).
-
Dean M, Rzhetsky A, Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily.
Genome Res. 11: 1156-1166 (2001).
*
-
Deane JA, Bolland S. Nucleic acid-sensing TLRs as modifiers of autoimmunity.
J. Immunol. 177: 6573-6578 (2006).
*
-
Deane JA, Pisitkun P, Barrett RS, Feigenbaum L, Town T, Ward JM, Flavell RA, Bolland S. Control of Toll-like receptor 7 expression is essential to restrict autoimmunity and dendritic cell proliferation.
Immunity 27: 801-810 (2007).
*
-
Deangelis RA, Markiewski MM, Taub R, Lambris JD. A high-fat diet impairs liver regeneration in C57BL/6 mice through overexpression of the NF-kappaB inhibitor, IkappaBalpha.
Hepatology 42: 1148-1157 (2005).
*
-
Deban L, Correale C, Vetrano S, Malesci A, Danese S. Multiple pathogenic roles of microvasculature in inflammatory bowel disease: a Jack of all trades.
Am. J. Pathol. 172: 1457-1466 (2008).
*
-
Debard C, Cozzone D, Ricard N, Vouillarmet J, Disse E, Husson B, Laville M, Vidal H. Short-term activation of peroxisome proliferator-activated receptor beta/delta increases fatty acid oxidation but does not restore insulin action in muscle cells from type 2 diabetic patients.
J. Mol. Med. 84: 747-752 (2006).
*
-
Debinski HS, Lee CS, Danks JA, Mackenzie PI, Desmond PV. Localization of uridine 5'-diphosphate-glucuronosyltransferase in human liver injury.
Gastroenterology 108: 1464-1469 (1995).
*
-
DeCicco KL, Youngdahl JD, Ross AC. All-trans-retinoic acid and polyriboinosinic : polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity.
Immunology 104: 341-348 (2001).
*
-
Deckelbaum RJ, Worgall TS, Seo T. n-3 Fatty acids and gene expression.
Am. J. Clin. Nutr. 83: 1520S-1525S (2006).
*
-
Decker P, Kotter I, Klein R, Berner B, Rammensee HG. Monocyte-derived dendritic cells over-express CD86 in patients with systemic lupus erythematosus.
Rheumatology (Oxford) 45: 1087-1095 (2006).
*
-
Decker T, Pasca di Magliano M, McManus S, Sun Q, Bonifer C, Tagoh H, Busslinger M. Stepwise activation of enhancer and promoter regions of the B cell commitment gene Pax5 in early lymphopoiesis.
Immunity 30: 508-520 (2009).
*
-
Dedoussis GV, Kapiri A, Kalogeropoulos N, Samara A, Dimitriadis D, Lambert D, Pfister M, Siest G, Visvikis-Siest S. Adipokine expression in adipose tissue and in peripheral blood mononuclear cells in children. Correlation with BMI and fatty acid content.
Clin. Chim. Acta 410: 85-89 (2009).
*
-
Dedoussis GV, Maumus S, Choumerianou DM, Skoumas J, Pitsavos C, Stefanadis C, Visvikis-Siest S. Different genes and polymorphisms affecting high-density lipoprotein cholesterol levels in Greek familial hypercholesterolemia patients.
Genet. Test. 10: 192-199 (2006).
-
Defaux A, Zurich MG, Braissant O, Honegger P, Monnet-Tschudi F. Effects of the PPAR-beta agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination.
J. Neuroinflammation 6: 15 (2009).
*
-
Degagne E, Grbic DM, Dupuis AA, Lavoie EG, Langlois C, Jain N, Weisman GA, Sevigny J, Gendron FP. P2Y2 receptor transcription is increased by NF-kappaB and stimulates cyclooxygenase-2 expression and PGE2 released by intestinal epithelial cells.
J. Immunol. 183: 4521-4529 (2009).
-
Degasperi GR, Romanatto T, Denis RG, Araujo EP, Moraes JC, Inada NM, Vercesi AE, Velloso LA. UCP2 protects hypothalamic cells from TNF-alpha-induced damage.
FEBS Lett. 582: 3103-3110 (2008).
*
-
Degenhardt T, Matilainen M, Herzig KH, Dunlop TW, Carlberg C. The insulin-like growth factor binding protein 1 gene is a primary target of peroxisome proliferator-activated receptors.
J. Biol. Chem. 281: 39607-39619 (2006).
*
-
Degenhardt T, Saramaki A, Malinen M, Rieck M, Vaisanen S, Huotari A, Herzig KH, Muller R, Carlberg C. Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.
J. Mol. Biol. 372: 341-355 (2007).
*
-
Degeorge KC, Degeorge BR, Testa JS, Rothstein JL. Inhibition of oncogene-induced inflammatory chemokines using a farnesyltransferase inhibitor.
J. Inflamm. (Lond.) 5: 3 (2008).
*
-
Degn SE, Hansen AG, Steffensen R, Jacobsen C, Jensenius JC, Thiel S. MAp44, a human protein associated with pattern recognition molecules of the complement system and regulating the lectin pathway of complement activation.
J. Immunol. 183: 7371-7378 (2009).
-
Deguara J, Burnand KG, Berg J, Green P, Lewis CM, Chinien G, Waltham M, Taylor P, Stern RF, Solomon E, Smith A. An increased frequency of the 5A allele in the promoter region of the MMP3 gene is associated with abdominal aortic aneurysms.
Hum. Mol. Genet. 16: 3002-3007 (2007).
*
-
Deguchi A, Arima K, Masaki T, Yachida M, Nakai S, Ito T, Kita Y, Kurokohchi K, Watanabe S, Kuriyama S. Enhanced expression of Bcl-2 in lymphocytes infiltrating into the liver of patients with primary biliary cirrhosis.
Int. J. Mol. Med. 9: 571-577 (2002).
-
Deichmann M, Thome M, Egner U, Hartschuh W, Kurzen H. The chemoresistance gene ABCG2 (MXR/BCRP1/ABCP1) is not expressed in melanomas but in single neuroendocrine carcinomas of the skin.
J. Cutan. Pathol. 32: 467-473 (2005).
*
-
Dejardin E, Droin NM, Delhase M, Haas E, Cao Y, Makris C, Li ZW, Karin M, Ware CF, Green DR. The lymphotoxin-beta receptor induces different patterns of gene expression via two NF-kappaB pathways.
Immunity 17: 525-535 (2002).
*
-
Dekaney CM, von Allmen DC, Garrison AP, Rigby RJ, Lund PK, Henning SJ, Helmrath MA. Bacterial-dependent up-regulation of intestinal bile acid binding protein and transport is FXR-mediated following ileo-cecal resection.
Surgery 144: 174-181 (2008).
-
Dekaney CM, Wu G, Yin YL, Jaeger LA. Regulation of ornithine aminotransferase gene expression and activity by all-trans retinoic acid in Caco-2 intestinal epithelial cells.
J. Nutr. Biochem. 19: 674-681 (2008).
*
-
Del Bas JM, Ricketts ML, Vaque M, Sala E, Quesada H, Ardevol A, Salvado MJ, Blay M, Arola L, Moore DD, Pujadas G, Fernandez-Larrea J, Blade C. Dietary procyanidins enhance transcriptional activity of bile acid-activated FXR in vitro and reduce triglyceridemia in vivo in a FXR-dependent manner.
Mol. Nutr. Food Res. 53: 805-814 (2009).
-
Del Campo AB, Aptsiauri N, Mendez R, Zinchenko S, Vales A, Paschen A, Ward S, Ruiz-Cabello F, Gonzalez-Aseguinolaza G, Garrido F. Efficient recovery of HLA class I expression in human tumor cells after beta2-microglobulin gene transfer using adenoviral vector: implications for cancer immunotherapy.
Scand. J. Immunol. 70: 125-135 (2009).
*
-
del Castillo-Olivares A, Campos JA, Pandak WM, Gil G. The role of alpha1-fetoprotein transcription factor/LRH-1 in bile acid biosynthesis: a known nuclear receptor activator that can act as a suppressor of bile acid biosynthesis.
J. Biol. Chem. 279: 16813-16821 (2004).
*
-
del Castillo-Olivares A, Gil G. Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7alpha-hydroxylase transcription.
Nucleic Acids Res. 28: 3587-3593 (2000).
*
-
del Fresno C, Garcia-Rio F, Gomez-Pina V, Soares-Schanoski A, Fernandez-Ruiz I, Jurado T, Kajiji T, Shu C, Marin E, Gutierrez del Arroyo A, Prados C, Arnalich F, Fuentes-Prior P, Biswas SK, Lopez-Collazo E. Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients.
J. Immunol. 182: 6494-6507 (2009).
-
del Fresno C, Gomez-Pina V, Lores V, Soares-Schanoski A, Fernandez-Ruiz I, Rojo B, Alvarez-Sala R, Caballero-Garrido E, Garcia F, Veliz T, Arnalich F, Fuentes-Prior P, García-Río F, Lopez-Collazo E. Monocytes from cystic fibrosis patients are locked in an LPS tolerance state: down-regulation of TREM-1 as putative underlying mechanism.
PLoS ONE 3: e2667 (2008).
*
-
del Rey A, Besedovsky HO. Sympathetic nervous system-immune interactions in autoimmune lymphoproliferative diseases.
Neuroimmunomodulation 15: 29-36 (2008).
-
Del Rey A, Roggero E, Kabiersch A, Schafer M, Besedovsky HO. The role of noradrenergic nerves in the development of the lymphoproliferative disease in Fas-deficient, lpr/lpr mice.
J. Immunol. 176: 7079-7086 (2006).
*
-
del Rincon I, Battafarano DF, Arroyo RA, Murphy FT, Escalante A. Heterogeneity between men and women in the influence of the HLA-DRB1 shared epitope on the clinical expression of rheumatoid arthritis.
Arthritis Rheum. 46: 1480-1488 (2002).
*
-
Del Rio Espínola A, Sole E, Montaner J. Pathophysiology of CADASIL disease.
Med. Clin. (Barc.) Dec 24 [Epub ahead of print] (2009).
-
Del Rio R, Noubade R, Subramanian M, Saligrama N, Diehl S, Rincon M, Teuscher C. SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3.
Genes Immun. 9: 115-121 (2008).
*
-
dela Pena A, Leclercq IA, Williams J, Farrell GC. NADPH oxidase is not an essential mediator of oxidative stress or liver injury in murine MCD diet-induced steatohepatitis.
J. Hepatol. 46: 304-313 (2007).
*
-
Delatycki MB, Powell LW, Allen KJ. Hereditary hemochromatosis genetic testing of at-risk children: what is the appropriate age?
Genet. Test. 8: 98-103 (2004).
-
Delaunay JL, Durand-Schneider AM, Delautier D, Rada A, Gautherot J, Jacquemin E, Ait-Slimane T, Maurice M. A missense mutation in ABCB4 gene involved in progressive familial intrahepatic cholestasis type 3 leads to a folding defect that can be rescued by low temperature.
Hepatology 49: 1218-1227 (2009).
*
-
Delbosc S, Glorian M, Le Port AS, Bereziat G, Andreani M, Limon I. The benefit of docosahexanoic acid on the migration of vascular smooth muscle cells is partially dependent on Notch regulation of MMP-2/-9.
Am. J. Pathol. 172: 1430-1440 (2008).
*
-
Deleeuw RJ, Zettl A, Klinker E, Haralambieva E, Trottier M, Chari R, Ge Y, Gascoyne RD, Chott A, Muller-Hermelink HK, Lam WL. Whole-genome analysis and HLA genotyping of enteropathy-type T-cell lymphoma reveals 2 distinct lymphoma subtypes.
Gastroenterology 132: 1902-1911 (2007).
*
-
Delerive P, Chin WW, Suen CS. Identification of Reverb(alpha) as a novel ROR(alpha) target gene.
J. Biol. Chem. 277: 35013-35018 (2002).
*
-
Delerive P, De Bosscher K, Besnard S, Vanden Berghe W, Peters JM, Gonzalez FJ, Fruchart JC, Tedgui A, Haegeman G, Staels B. Peroxisome proliferator-activated receptor alpha negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-kappaB and AP-1.
J. Biol. Chem. 274: 32048-32054 (1999).
*
-
Delerive P, Galardi CM, Bisi JE, Nicodeme E, Goodwin B. Identification of liver receptor homolog-1 as a novel regulator of apolipoprotein AI gene transcription.
Mol. Endocrinol. 18: 2378-2387 (2004).
*
-
Delerive P, Gervois P, Fruchart JC, Staels B. Induction of IkappaBalpha expression as a mechanism contributing to the anti-inflammatory activities of peroxisome proliferator-activated receptor-alpha activators.
J. Biol. Chem. 275: 36703-36707 (2000).
*
-
Deleuran B, Abraham DJ. Possible implication of the effector CD4(+) T-cell subpopulation T(H)17 in the pathogenesis of systemic scleroderma.
Nat. Clin. Pract. Rheumatol. 3: 682-683 (2007).
*
-
Deleuze JF, Jacquemin E, Dubuisson C, Cresteil D, Dumont M, Erlinger S, Bernard O, Hadchouel M. Defect of multidrug-resistance 3 gene expression in a subtype of progressive familial intrahepatic cholestasis.
Hepatology 23: 904-908 (1996).
*
-
Delgado F, Estrada-Chavez C, Romano M, Paolicchi F, Blanco-Viera F, Capellino F, Chavez-Gris G, Pereira-Suarez AL. Expression of NRAMP1 and iNOS in Mycobacterium avium subsp. paratuberculosis naturally infected cattle.
Comp. Immunol. Microbiol. Infect. Dis. Apr 3 [Epub ahead of print] (2009).
*
-
Delgado M, Robledo G, Rueda B, Varela N, O'Valle F, Hernandez-Cortes P, Caro M, Orozco G, Gonzalez-Rey E, Martin J. Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: altered expression and signal in immune cells.
Arthritis Rheum. 58: 1010-1019 (2008).
*
-
Delgado MA, Elmaoued RA, Davis AS, Kyei G, Deretic V. Toll-like receptors control autophagy.
EMBO J. 27: 1110-1121 (2008).
*
-
Delgado-Escueta AV, White R, Greenberg DA, Treiman LJ. Looking for epilepsy genes: clinical and molecular genetic studies.
Adv. Neurol. 44: 77-95 (1986).
-
Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishy S, Haussinger D, Wunderlich F. Loss to self-heal malaria upon taurine transporter deletion.
Infect. Immun. Jan 25 [Epub ahead of print] (2010).
*
-
Delimaprata K, Orellana MD, De Santis GC, Kashima S, Fontes AM, Decassiaviucarrara R, Boninipalma PV, Neder L, Covas DT. Effects of high dose chemotherapy on bone marrow multipotent mesenchymal stromal cells isolated from lymphoma patients.
Exp. Hematol. Feb 4 [Epub ahead of print] (2010).
-
Delmotte MH, Tahayato A, Formstecher P, Lefebvre P. Serine 157, a retinoic acid receptor alpha residue phosphorylated by protein kinase C in vitro, is involved in RXR.RARalpha heterodimerization and transcriptional activity.
J. Biol. Chem. 274: 38225-38231 (1999).
*
-
Delogu LG, Magrini A, Bergamaschi A, Rosato N, Dawson MI, Bottini N, Bottini M. Conjugation of antisense oligonucleotides to PEGylated carbon nanotubes enables efficient knockdown of PTPN22 in T lymphocytes.
Bioconjug. Chem. 20: 427-431 (2009).
*
-
Deluca DS, Blasczyk R. The immunoinformatics of cancer immunotherapy.
Tissue Antigens 70: 265-271 (2007).
*
-
Delvecchio CJ, Bilan P, Radford K, Stephen J, Trigatti BL, Cox G, Parameswaran K, Capone JP. Liver X receptor stimulates cholesterol efflux and inhibits expression of pro-inflammatory mediators in human airway smooth muscle cells.
Mol. Endocrinol. 21: 1324-1334 (2007).
*
-
Demacq C, de Souza AP, Machado AA, Gerlach RF, Tanus-Santos JE. Genetic polymorphism of matrix metalloproteinase (MMP)-9 does not affect plasma MMP-9 activity in healthy subjects.
Clin. Chim. Acta 365: 183-187 (2006).
*
-
Demay MB, Macdonald PN, Skorija K, Dowd DR, Cianferrotti L, Cox M. Role of the vitamin D receptor in hair follicle biology.
J. Steroid Biochem. Mol. Biol. 103: 344-346 (2007).
-
Demedts IK, Bracke KR, Maes T, Joos GF, Brusselle GG. Different roles for human lung dendritic cell subsets in pulmonary immune defense mechanisms.
Am. J. Respir. Cell. Mol. Biol. 35: 387-393 (2006).
*
-
Demeilliers C, Jacquemin E, Barbu V, Mergey M, Paye F, Fouassier L, Chignard N, Housset C, Lomri NE. Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation.
Hepatology 43: 1125-1134 (2006).
*
-
Demetris AJ, Specht S, Nozaki I, Lunz JG 3rd, Stolz DB, Murase N, Wu T. Small proline-rich proteins (SPRR) function as SH3 domain ligands, increase resistance to injury and are associated with epithelial-mesenchymal transition (EMT) in cholangiocytes.
J. Hepatol. 48: 276–288 (2008).
*
-
Demirci FY, Manzi S, Ramsey-Goldman R, Minster RL, Kenney M, Shaw PS, Dunlop-Thomas CM, Kao AH, Rhew E, Bontempo F, Kammerer C, Kamboh MI. Association of a common interferon regulatory factor 5 (IRF5) variant with increased risk of systemic lupus erythematosus (SLE).
Ann. Hum. Genet. 71: 308-311 (2007).
*
-
Demirkiran A, Baan CC, Kok A, Metselaar HJ, Tilanus HW, van der Laan LJ. Intrahepatic detection of FOXP3 gene expression after liver transplantation using minimally invasive aspiration biopsy.
Transplantation 83: 819-823 (2007).
-
Dempke W, Rie C, Grothey A, Schmoll HJ. Cyclooxygenase-2: a novel target for cancer chemotherapy?
J. Cancer Res. Clin. Oncol. 127: 411-417 (2001).
*
-
den Hollander AI, Roepman R, Koenekoop RK, Cremers FP. Leber congenital amaurosis: genes, proteins and disease mechanisms.
Prog. Retin. Eye Res. 27: 391-419 (2008).
-
Denardo GL, Natarajan A, Hok S, Perkins J, Cosman M, Denardo SJ, Lightstone FC, Mirick GR, Miers LA, Balhorn RL. Pharmacokinetic characterization in xenografted mice of a series of first-generation mimics for HLA-DR antibody, Lym-1, as carrier molecules to image and treat lymphoma.
J. Nucl. Med. 48: 1338-1347 (2007).
-
Dendrou CA, Plagnol V, Fung E, Yang JH, Downes K, Cooper JD, Nutland S, Coleman G, Himsworth M, Hardy M, Burren O, Healy B, Walker NM, Koch K, Ouwehand WH, Bradley JR, Wareham NJ, Todd JA, Wicker LS. Cell-specific protein phenotypes for the autoimmune locus IL2RA using a genotype-selectable human bioresource.
Nat. Genet. 41: 1011-1015 (2009).
*
-
Denechaud PD, Bossard P, Lobaccaro JM, Millatt L, Staels B, Girard J, Postic C. ChREBP, but not LXRs, is required for the induction of glucose-regulated genes in mouse liver.
J. Clin. Invest. 118: 956-964 (2008).
*
-
Deng A, Yao D, Chen S, Liu C, Kang J, Zhou Y, Yu H, Qian C, Wu C, Jiang T, Zhong R, Pei G. beta-Arrestin 1 contributes to primary biliary cirrhosis.
Clin. Sci. (Lond.) Dec 21 [Epub ahead of print] (2009).
*
-
Deng G, Zhou G, Zhang R, Zhai Y, Zhao W, Yan Z, Deng C, Yuan X, Xu B, Dong X, Zhang X, Zhang X, Yao Z, Shen Y, Qiang B, Wang Y, He F. Regulatory polymorphisms in the promoter of CXCL10 gene and disease progression in male hepatitis B virus carriers.
Gastroenterology 134: 716-726.e2 (2008).
*
-
Deng GM. Tumor necrosis factor receptor pre-ligand assembly domain is an important therapeutic target in inflammatory arthritis.
BioDrugs 21: 23-29 (2007).
-
Deng H, Yang X, Jin T, Wu J, Hu LS, Chang M, Sun XJ, Adem A, Winblad B, Zhu J. The role of IL-12 and TNF-alpha in AIDP and AMAN.
Eur. J. Neurol. 15: 1100-1105 (2008).
-
Deng Q, Mancini-Bourgine M, Zhang X, Cumont MC, Zhu R, Lone YC, Michel ML. Hepatitis B virus as a gene delivery vector activating foreign antigenic T cell response that abrogates viral expression in mouse models.
Hepatology 50: 1380-1391 (2009).
-
Deng QG, She H, Cheng JH, French SW, Koop DR, Xiong S, Tsukamoto H. Steatohepatitis induced by intragastric overfeeding in mice.
Hepatology 42: 905-914 (2005).
*
-
Deng R, Yang D, Radke A, Yang J, Yan B. Hypolipidemic agent guggulsterone regulates the expression of human bile salt export pump: dominance of transactivation over FXR-mediated antagonism.
J. Pharmacol. Exp. Ther. 320: 1153-1162 (2007).
*
-
Deng R, Yang D, Yang J, Yan B. Oxysterol 22(R)-hydroxycholesterol induces the expression of the bile salt export pump through nuclear receptor FXR but not LXR.
J. Pharmacol. Exp. Ther. 317: 317-325 (2006).
*
-
Deng T, Shan S, Li ZB, Wu ZW, Liao CZ, Ko B, Lu XP, Cheng J, Ning ZQ. A new retinoid-like compound that activates peroxisome proliferator-activated receptors and lowers blood glucose in diabetic mice.
Biol. Pharm. Bull. 28: 1192-1196 (2005).
*
-
Deng X, Stachlewitz RF, Liguori MJ, Blomme EA, Waring JF, Luyendyk JP, Maddox JF, Ganey PE, Roth RA. Modest inflammation enhances diclofenac hepatotoxicity in rats: role of neutrophils and bacterial translocation.
J. Pharmacol. Exp. Ther. 319: 1191-1199 (2006).
*
-
Deng X, Tolstanova G, Khomenko T, Chen L, Tarnawski AS, Szabo S, Sandor Z. Mesalamine restores angiogenic balance in experimental ulcerative colitis by reducing expression of endostatin and angiostatin: novel molecular mechanism for mesalamine's therapeutic action.
J. Pharmacol. Exp. Ther. 331: 1071-1078 (2009).
*
-
Deng X, Yellaturu C, Cagen L, Wilcox HG, Park EA, Raghow R, Elam MB. Expression of the rat sterol regulatory element binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).
J. Biol. Chem. 282: 17517-17529 (2007).
*
-
Deng YJ, Huang ZX, Zhou CJ, Wang JW, You Y, Song ZQ, Xiang MM, Zhong BY, Hao F. Gene profiling involved in immature CD4+ T lymphocyte responsible for systemic lupus erythematosus.
Mol. Immunol. 43: 1497-1507 (2006).
*
-
Deng YN, Zhou WB. Expression of TLR4 and TLR9 mRNA in Lewis rats with experimental allergic neuritis.
Neuroimmunomodulation 14: 336-342 (2008).
-
Dengler HS, Baracho GV, Omori SA, Bruckner S, Arden KC, Castrillon DH, Depinho RA, Rickert RC. Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation.
Nat. Immunol. 9: 1388-1398 (2008).
*
-
Denis M, Bissonnette R, Haidar B, Krimbou L, Bouvier M, Genest J. Expression, regulation, and activity of ABCA1 in human cell lines.
Mol. Genet. Metab. 78: 265-274 (2003).
*
-
Denk GU, Cai SY, Chen WS, Lin A, Soroka CJ, Boyer JL. A comparison of gene expression in mouse liver and kidney in obstructive cholestasis utilizing high-density oligonucleotide microarray technology.
World J. Gastroenterol. 12: 2536-2548 (2006).
*
-
Denk H. Alcoholic hepatitis and Mallory bodies.
Falk Symposium 137. XII FALK LIVER WEEK 2003 (Part II) In honour of Hans Popper’s 100th Birthday. Liver Diseases: Advances in Treatment and Prevention. Freiburg (Germany). p. 46. October 17 - 19 (2003). *
-
Denman CJ, McCracken J, Hariharan V, Klarquist J, Oyarbide-Valencia K, Guevara-Patino JA, Caroline Le Poole I. HSP70i accelerates depigmentation in a mouse model of autoimmune vitiligo.
J. Invest. Dermatol. 128: 2041-2048 (2008).
*
-
Denning GM, Stoll LL. Peroxisome proliferator-activated receptors: potential therapeutic targets in lung disease?
Pediatr. Pulmonol. 41: 23-34 (2006).
-
Denning K, Smyth P, Cahill S, Li J, Flavin R, Aherne S, O' Leary JJ, Sheils O. ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells.
Mol. Cancer 7: 44 (2008).
*
-
Denoeud F, Kapranov P, Ucla C, Frankish A, Castelo R, Drenkow J, Lagarde J, Alioto T, Manzano C, Chrast J, Dike S, Wyss C, Henrichsen CN, Holroyd N, Dickson MC, Taylor R, Hance Z, Foissac S, Myers RM, Rogers J, Hubbard T, Harrow J, Guigo R, et al. Prominent use of distal 5' transcription start sites and discovery of a large number of additional exons in ENCODE regions.
Genome Res. 17: 746-759 (2007).
*
-
Denson LA, McClure MH, Bogue CW, Karpen SJ, Jacobs HC. HNF3beta and GATA-4 transactivate the liver-enriched homeobox gene, Hex.
Gene 246: 311-320 (2000).
*
-
Denson LA, Sturm E, Echevarria W, Zimmerman TL, Makishima M, Mangelsdorf DJ, Karpen SJ. The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp.
Gastroenterology 121: 140-147 (2001).
*
-
Dentelli P, Trombetta A, Togliatto G, Zeoli A, Rosso A, Uberti B, Orso F, Taverna D, Pegoraro L, Brizzi MF. Formation of STAT5/PPARgamma transcriptional complex modulates angiogenic cell bioavailability in diabetes.
Arterioscler. Thromb. Vasc. Biol. 29: 114-120 (2009).
-
Dentin R, Benhamed F, Pegorier JP, Foufelle F, Viollet B, Vaulont S, Girard J, Postic C. Polyunsaturated fatty acids suppress glycolytic and lipogenic genes through the inhibition of ChREBP nuclear protein translocation.
J. Clin. Invest. 115: 2843-2854 (2005).
*
-
Denucci CC, Pagan AJ, Mitchell JS, Shimizu Y. Control of alpha4beta7 integrin expression and CD4 T cell homing by the beta1 integrin subunit.
J. Immunol. Jan 29 [Epub ahead of print] (2010).
-
Denys A, Hichami A, Khan NA. n-3 PUFAs modulate T-cell activation via protein kinase C-alpha and -epsilon and NF-kappa B signaling pathway.
J. Lipid Res. 46: 752-758 (2005).
*
-
Depetris M, Casalis P, Kratje R, Etcheverrigaray M, Oggero M. A scFv antibody fragment as a therapeutic candidate to neutralize a broad diversity of human IFN-alpha subtypes.
J. Immunol. Methods 334: 104-113 (2008).
*
-
Depil S, Morales O, Castelli FA, Delhem N, Francois V, Georges B, Dufosse F, Morschhauser F, Hammer J, Maillere B, Auriault C, Pancre V. Determination of a HLA II promiscuous peptide cocktail as potential vaccine against EBV latency II malignancies.
J. Immunother. 30: 215-226 (2007).
-
Deplancke B, Gaskins HR. Microbial modulation of innate defense: goblet cells and the intestinal mucus layer.
Am. J. Clin. Nutr. 73: 1131S-1141S (2001).
*
-
Derbinski J, Kyewski B. Linking signalling pathways, thymic stroma integrity and autoimmunity.
Trends Immunol. 26: 503-506 (2005).
*
-
Derecka K, Sheldrick EL, Wathes DC, Abayasekara DR, Flint AP. A PPAR-independent pathway to PUFA-induced COX-2 expression.
Mol. Cell. Endocrinol. 287: 65-71 (2008).
-
Derhovanessian E, Adams V, Hahnel K, Groeger A, Pandha H, Ward S, Pawelec G. Pretreatment frequency of circulating IL-17(+)CD4(+) T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients.
Int. J. Cancer 125: 1372-1379 (2009).
*
-
Deroee AF, Oweinah J, Naraghi M, Hosemann W, Athari B, Volker U, Scharf C. Regression of polypoid nasal mucosa after systemic corticosteroid therapy: a proteomics study.
Am. J. Rhinol. Allergy 23: 480-485 (2009).
-
Derudder E, Cadera EJ, Vahl JC, Wang J, Fox CJ, Zha S, van Loo G, Pasparakis M, Schlissel MS, Schmidt-Supprian M, Rajewsky K. Development of immunoglobulin lambda-chain-positive B cells, but not editing of immunoglobulin kappa-chain, depends on NF-kappaB signals.
Nat. Immunol. 10: 647-654 (2009).
*
-
Desai S, Bolick SC, Maurin M, Wright KL. PU.1 regulates positive regulatory domain I-binding factor 1/Blimp-1 transcription in lymphoma cells.
J. Immunol. 183: 5778-5787 (2009).
-
Descamps D, Le Gars M, Hong SS, Granio O, Huerre M, Chignard M, Sallenave JM. Modulation of the pro-inflammatory phenotype of CFTR mutated epithelial cells.
Rev. Mal. Respir. 25: 1183 (2008).
-
Descamps D, Vigant F, Esselin S, Connault E, Opolon P, Perricaudet M, Benihoud K. Expression of non-signaling membrane-anchored death receptors protects murine livers in different models of hepatitis.
Hepatology 44: 399-409 (2006).
*
-
Desch M, Schreiber A, Schweda F, Madsen K, Friis UG, Weatherford ET, Sigmund CD, Sequeira Lopez ML, Gomez RA, Todorov VT. Increased renin production in mice with deletion of peroxisome proliferator-activated receptor-gamma in juxtaglomerular cells.
Hypertension Jan 11 [Epub ahead of print] (2010).
-
Desideri G, Croce G, Tucci M, Passacquale G, Broccoletti S, Valeri L, Santucci A, Ferri C. Effects of bezafibrate and simvastatin on endothelial activation and lipid peroxidation in hypercholesterolemia: evidence of different vascular protection by different lipid-lowering treatments.
J. Clin. Endocrinol. Metab. 88: 5341-5437 (2003).
*
-
Desiderio S, Yoo JY. A genome-wide analysis of the acute-phase response and its regulation by Stat3beta.
Ann. N. Y. Acad. Sci. 987: 280-284 (2003).
*
-
Desmetz C, Lin YL, Mettling C, Portales P, Rabesandratana H, Clot J, Corbeau P. The strength of the chemotactic response to a CCR5 binding chemokine is determined by the level of cell surface CCR5 density.
Immunology 119: 551-561 (2006).
*
-
Dessein R, Chamaillard M, Danese S. Innate immunity in Crohn's disease: the reverse side of the medal.
J. Clin. Gastroenterol. 42 Suppl. 3 Pt. 1: S144-S147 (2008).
-
Dessein R, Gironella M, Vignal C, Peyrin-Biroulet L, Sokol H, Secher T, Lacas-Gervais S, Gratadoux JJ, Lafont F, Dagorn JC, Ryffel B, Akira S, Langella P, Nunez G, Sirard JC, Iovanna J, Simonet M, Chamaillard M. Toll-like receptor 2 is critical for induction of Reg3beta expression and intestinal clearance of Yersinia pseudotuberculosis.
Gut 58: 771-776 (2009).
-
Desvergne B, IJpenberg A, Devchand PR, Wahli W. The peroxisome proliferator-activated receptors at the cross-road of diet and hormonal signalling.
J. Steroid Biochem. Mol. Biol. 65: 65-74 (1998).
-
Detrick B, Lee MT, Chin MS, Hooper LC, Chan CC, Hooks JJ. Experimental coronavirus retinopathy (ECOR): retinal degeneration susceptible mice have an augmented interferon and chemokine (CXCL9, CXCL10) response early after virus infection.
J. Neuroimmunol. 193: 28-37 (2008).
-
Detro-Dassen S, Schanzler M, Lauks H, Martin I, Meyer Zu Berstenhorst S, Nothmann D, Torres-Salazar D, Hidalgo P, Schmalzing G, Fahlke C. Conserved dimeric subunit stoichiometry of SLC26 multifunctional anion exchangers.
J. Biol. Chem. 283: 4177-4188 (2008).
*
-
Deugnier Y, Le Gall JY. Should we support large-scale screening for genetic haemochromatosis in France?
Bull. Acad. Natl. Med. 188: 265-272 (2004).
-
Devauchelle V, Essabbani A, De Pinieux G, Germain S, Tourneur L, Mistou S, Margottin-Goguet F, Anract P, Migaud H, Le Nen D, Lequerre T, Saraux A, Dougados M, Breban M, Fournier C, Chiocchia G. Characterization and functional consequences of underexpression of clusterin in rheumatoid arthritis.
J. Immunol. 177: 6471-6479 (2006).
*
-
Devauchelle V, Marion S, Cagnard N, Mistou S, Falgarone G, Breban M, Letourneur F, Pitaval A, Alibert O, Lucchesi C, Anract P, Hamadouche M, Ayral X, Dougados M, Gidrol X, Fournier C, Chiocchia G. DNA microarray allows molecular profiling of rheumatoid arthritis and identification of pathophysiological targets.
Genes Immun. 5: 597-608 (2004).
*
-
Devaux PF, Lopez-Montero I, Bryde S. Proteins involved in lipid translocation in eukaryotic cells.
Chem. Phys. Lipids 141: 119-132 (2006).
-
Devchand PR, Ijpenberg A, Devesvergne B, Wahli W. PPARs: nuclear receptors for fatty acids, eicosanoids, and xenobiotics.
Adv. Exp. Med. Biol. 469: 231-236 (1999).
-
Devitt G, Meyer C, Wiedemann N, Eichmuller S, Kopp-Schneider A, Haferkamp A, Hautmann R, Zoller M. Serological analysis of human renal cell carcinoma.
Int. J. Cancer 118: 2210-2219 (2006).
*
-
Devoss J, Hou Y, Johannes K, Lu W, Liou GI, Rinn J, Chang H, Caspi R, Fong L, Anderson MS. Spontaneous autoimmunity prevented by thymic expression of a single self-antigen.
J. Exp. Med. 203: 2727-2735 (2006).
*
-
Devosse T, Guillabert A, D'Haene N, Berton A, De Nadai P, Noel S, Brait M, Franssen JD, Sozzani S, Salmon I, Parmentier M. Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils.
J. Immunol. 182: 4974-4984 (2009).
-
Dewitt JC, Shnyra A, Badr MZ, Loveless SE, Hoban D, Frame SR, Cunard R, Anderson SE, Meade BJ, Peden-Adams MM, Luebke RW, Luster MI. Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha.
Crit. Rev. Toxicol. 39: 76-94 (2009).
-
Dey I, Lejeune M, Chadee K. Prostaglandin E2 receptor distribution and function in the gastrointestinal tract.
Br. J. Pharmacol. 149: 611-623 (2006).
*
-
Dezso K, Jelnes P, Laszlo V, Baghy K, Bodor C, Paku S, Tygstrup N, Bisgaard HC, Nagy P. Thy-1 is expressed in hepatic myofibroblasts and not oval cells in stem cell-mediated liver regeneration.
Am. J. Pathol. 171: 1529-1537 (2007).
*
-
Dezso Z, Nikolsky Y, Nikolskaya T, Miller J, Cherba D, Webb C, Bugrim A. Identifying disease-specific genes based on their topological significance in protein networks.
BMC Syst. Biol. 3: 36 (2009).
*
-
Dhadialla PS, Ohiorhenuan IE, Cohen A, Strickland S. Maximum-entropy network analysis reveals a role for tumor necrosis factor in peripheral nerve development and function.
Proc. Natl. Acad. Sci. U.S.A. 106: 12494-12499 (2009).
*
-
Dharancy S, Malapel M, Perlemuter G, Roskams T, Cheng Y, Dubuquoy L, Podevin P, Conti F, Canva V, Philippe D, Gambiez L, Mathurin P, Paris JC, Schoonjans K, Calmus Y, Pol S, Auwerx J, Desreumaux P. Impaired expression of the peroxisome proliferator-activated receptor alpha during hepatitis C virus infection.
Gastroenterology 128: 334-342 (2005).
*
-
Dheen ST, Jun Y, Yan Z, Tay SS, Ling EA. Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia.
Glia 50: 21-31 (2005).
*
-
Dhillon NK, Mudryj M. Cyclin E overexpression enhances cytokine-mediated apoptosis in MCF7 breast cancer cells.
Genes Immun. 4: 336-342 (2003).
*
-
Di Campli C, Gasbarrini G, Gasbarrini A. Review article: a medicine based on cell transplantation - is there a future for treating liver diseases?
Aliment. Pharmacol. Ther. 18: 473-480 (2003).
*
-
Di Cristofaro J, Silvy M, Lanteaume A, Marcy M, Carayon P, De Micco C. Expression of tpo mRNA in thyroid tumors: quantitiative PCR analysis and correlation with alterations of ret, Braf, ras and pax8 genes.
Endocr. Relat. Cancer 13: 485-495 (2006).
*
-
Di Girolamo N, Indoh I, Jackson N, Wakefield D, McNeil HP, Yan W, Geczy C, Arm JP, Tedla N. Human mast cell-derived gelatinase B (matrix metalloproteinase-9) is regulated by inflammatory cytokines: role in cell migration.
J. Immunol. 177: 2638-2650 (2006).
*
-
Di Gregorio C, Frattini M, Maffei S, Ponti G, Losi L, Pedroni M, Venesio T, Bertario L, Varesco L, Risio M, de Leon MP. Immunohistochemical expression of MYH protein can be used to identify patients with MYH-associated polyposis.
Gastroenterology 131: 439-444 (2006).
*
-
Di Mola FF, Di Sebastiano P, Gardini A, Innocenti P, Zimmermann A, Buchler MW, Friess H. Differential expression of connective tissue growth factor in inflammatory bowel disease.
Digestion 69: 245-253 (2004).
-
Di Niro R, Ziller F, Florian F, Crovella S, Stebel M, Bestagno M, Burrone O, Bradbury AR, Secco P, Marzari R, Sblattero D. Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models.
BMC Biotechnol. 7: 46 (2007).
*
-
Di Nunzio M, Danesi F, Bordoni A. n-3 PUFA as regulators of cardiac gene transcription: a new link between PPAR activation and fatty acid composition.
Lipids Oct 27 [Epub ahead of print] (2009).
-
Di Nunzio S, Cecconi M, Passerini L, McMurchy AN, Baron U, Turbachova I, Vignola S, Valencic E, Tommasini A, Junker A, Cazzola G, Olek S, Levings MK, Perroni L, Roncarolo MG, Bacchetta R. Wild-type FOXP3 is selectively active in CD4+CD25hi regulatory T cells of healthy female carriers of different FOXP3 mutations.
Blood 114: 4138-4141 (2009).
*
-
Di Paola JA, Buchanan GR. Immune thrombocytopenic purpura.
Pediatr. Clin. North Am. 49: 911-928 (2002).
-
Di Pierro E, Cappellini MD, Mazzucchelli R, Moriondo V, Mologni D, Poma BZ, Riva A. A point mutation affecting an SP1 binding site in the promoter of the ferrochelatase gene impairs gene transcription and causes erythropoietic protoporphyria.
Exp. Hematol. 33: 584-591 (2005).
*
-
Di Renzo F, Corsini E, Broccia ML, Marinovich M, Galli CL, Giavini E, Menegola E. Molecular mechanism of teratogenic effects induced by the fungicide triadimefon: study of the expression of TGF-beta mRNA and TGF-beta and CRABPI proteins during rat in vitro development.
Toxicol. Appl. Pharmacol. 234: 107-116 (2009).
*
-
Di Sabatino A, Ciccocioppo R, Cupelli F, Cinque B, Millimaggi D, Clarkson MM, Paulli M, Cifone MG, Corazza GR. Epithelium derived interleukin 15 regulates intraepithelial lymphocyte Th1 cytokine production, cytotoxicity, and survival in coeliac disease.
Gut 55: 469-477 (2006).
*
-
Di Sabatino A, Ciccocioppo R, D'Alo S, Parroni R, Millimaggi D, Cifone MG, Corazza GR. Intraepithelial and lamina propria lymphocytes show distinct patterns of apoptosis whereas both populations are active in Fas based cytotoxicity in coeliac disease.
Gut 49: 380-386 (2001).
*
-
Di Sabatino A, Ciccocioppo R, Luinetti O, Ricevuti L, Morera R, Cifone MG, Solcia E, Corazza GR. Increased enterocyte apoptosis in inflamed areas of Crohn's disease.
Dis. Colon Rectum 46: 1498-1507 (2003).
-
Di Sabatino A, Rovedatti L, Kaur R, Spencer JP, Brown JT, Morisset VD, Biancheri P, Leakey NA, Wilde JI, Scott L, Corazza GR, Lee K, Sengupta N, Knowles CH, Gunthorpe MJ, McLean PG, Macdonald TT, Kruidenier L. Targeting gut T cell Ca2+ release-activated Ca2+ channels inhibits T cell cytokine production and T-box transcription factor T-bet in inflammatory bowel disease.
J. Immunol. 183: 3454-3462 (2009).
-
Di Sabatino A, Rovedatti L, Rosado MM, Carsetti R, Corazza GR, Macdonald TT. Increased expression of mucosal addressin cell adhesion molecule 1 in the duodenum of patients with active celiac disease is associated with depletion of integrin alpha(4)beta(7)-positive T cells in blood.
Hum. Pathol. 40: 699-704 (2009).
-
Di Sebastiano P, di Mola FF, Di Febbo C, Baccante G, Porreca E, Innocenti P, Friess H, Buchler MW. Expression of interleukin 8 (IL-8) and substance P in human chronic pancreatitis.
Gut 47: 423-428 (2000).
*
-
Di Toro R, Campana G, Murari G, Spampinato S. Effects of specific bile acids on c-fos messenger RNA levels in human colon carcinoma Caco-2 cells.
Eur. J. Pharm. Sci. 11: 291-298 (2000).
*
-
Di WL, Hennekam RC, Callard RE, Harper JI. A heterozygous null mutation combined with the G1258A polymorphism of SPINK5 causes impaired LEKTI function and abnormal expression of skin barrier proteins.
Br. J. Dermatol. 161: 404-412 (2009).
*
-
Di YM, Chan E, Wei MQ, Liu JP, Zhou SF. Prediction of deleterious non-synonymous single-nucleotide polymorphisms of human uridine diphosphate glucuronosyltransferase genes.
AAPS J. 11: 469-480 (2009).
-
Di YM, Chow VD, Yang LP, Zhou SF. Structure, function, regulation and polymorphism of human cytochrome P450 2A6.
Curr. Drug Metab. Sep 1 [Epub ahead of print] (2009).
-
Di ZL, Niu XL, Wei J, Li YQ, Chen GL, Wang NP. Expression of peroxisome proliferator-activated receptors Y changes with age in vascular smooth muscle cells of spontaneously hypertensive rat.
Sichuan Da Xue Xue Bao Yi Xue Ban 37: 204-207 (2006).
-
Di-Poi N, Desvergne B, Michalik L, Wahli W. Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.
J. Biol. Chem. 280: 38700-38710 (2005).
*
-
Diab A, Hussain RZ, Lovett-Racke AE, Chavis JA, Drew PD, Racke MK. Ligands for the peroxisome proliferator-activated receptor-gamma and the retinoid X receptor exert additive anti-inflammatory effects on experimental autoimmune encephalomyelitis.
J. Neuroimmunol. 148: 116-126 (2004).
-
Dialynas DP, Rodgers VD. Anomalous leukopoiesis in two patients with Crohn's disease.
J. Clin. Gastroenterol. 34: 64-71 (2002).
-
Diamond DL, Proll SC, Jacobs JM, Chan EY, Camp DG 2nd, Smith RD, Katze MG. HepatoProteomics: applying proteomic technologies to the study of liver function and disease.
Hepatology 44: 299-308 (2006).
*
-
Dias S, Mansson R, Gurbuxani S, Sigvardsson M, Kee BL. E2A proteins promote development of lymphoid-primed multipotent progenitors.
Immunity 29: 217-227 (2008).
*
-
Diatchenko L, Romanov S, Malinina I, Clarke J, Tchivilev I, Li X, Makarov SS. Identification of novel mediators of NF-kappaB through genome-wide survey of monocyte adherence-induced genes.
J. Leukoc. Biol. 78: 1366-1377 (2005).
*
-
Diaz-Carballo D, Freista Hler M, Malak S, Bardenheuer W, Reusch HP. Mucronulatol from Caribbean propolis exerts cytotoxic effects on human tumor cell lines.
Int. J. Clin. Pharmacol. Ther. 46: 226-235 (2008).
-
Diaz-Sanjuan T, Garcia-Ruiz I, Rodriguez-Juan C, Munoz-Yague T, Solis-Munoz P, Solís-Herruzo JA. Interferon alpha increases metalloproteinase-13 gene expression through a polyomavirus enhancer activator 3-dependent pathway in hepatic stellate cells.
J. Hepatol. 50: 128-139 (2009).
*
-
Diaz-Viciedo R, Hortelano S, Giron N, Masso JM, Rodriguez B, Villar A, de Las Heras B. Modulation of inflammatory responses by diterpene acids from Helianthus annuus L.
Biochem. Biophys. Res. Commun. 369: 761-766 (2008).
*
-
Dib SA. Heterogeneity of type 1 diabetes mellitus.
Arq. Bras. Endocrinol. Metabol. 52: 205-218 (2008).
-
Diblasio-Smith EA, Arai M, Quinet EM, Evans MJ, Kornaga T, Basso MD, Chen L, Feingold I, Halpern AR, Liu QY, Nambi P, Savio D, Wang S, Mounts WM, Isler JA, Slager AM, Burczynski ME, Dorner AJ, Lavallie ER. Discovery and implementation of transcriptional biomarkers of synthetic LXR agonists in peripheral blood cells.
J. Transl. Med. 6: 59 (2008).
*
-
Dick EP, Prince LR, Prestwich EC, Renshaw SA, Whyte MK, Sabroe I. Pathways regulating lipopolysaccharide-induced neutrophil survival revealed by lentiviral transduction of primary human neutrophils.
Immunology 127: 249-255 (2009).
-
Dickensheets H, Vazquez N, Sheikh F, Gingras S, Murray PJ, Ryan JJ, Donnelly RP. Suppressor of cytokine signaling-1 is an IL-4-inducible gene in macrophages and feedback inhibits IL-4 signaling.
Genes Immun. 8: 21-27 (2007).
*
-
Dickey W. Joint BAPEN and British Society of Gastroenterology Symposium on 'Coeliac disease: basics and controversies'. Coeliac disease in the twenty-first century.
Proc. Nutr. Soc. 68: 234-241 (2009).
*
-
Dickins RA, McJunkin K, Hernando E, Premsrirut PK, Krizhanovsky V, Burgess DJ, Kim SY, Cordon-Cardo C, Zender L, Hannon GJ, Lowe SW. Tissue-specific and reversible RNA interference in transgenic mice.
Nat. Genet. 39: 914-921 (2007).
*
-
Diczfalusy U, Olofsson KE, Carlsson AM, Gong M, Golenbock DT, Rooyackers O, Flaring U, Bjorkbacka H. Marked up-regulation of cholesterol 25-hydroxylase expression by lipopolysaccharide.
J. Lipid Res. 50: 2258-2264 (2009).
*
-
Didilescu AC, Hanganu SC, Galie N, Greabu M, Totan A, Stratul SI, Puiu L. The role of smoking in changing essential parameters in body homeostasis.
Pneumologia 58: 89-94 (2009).
-
Dieckgraefe BK, Korzenik JR, Husain A, Dieruf L. Association of glycogen storage disease 1b and Crohn disease: results of a North American survey.
Eur. J. Pediatr. 161 Suppl. 1: S88-S92 (2002).
-
Dieckgraefe BK, Stenson WF, Korzenik JR, Swanson PE, Harrington CA. Analysis of mucosal gene expression in inflammatory bowel disease by parallel oligonucleotide arrays.
Physiol. Genomics 4: 1-11 (2000).
*
-
Diede SJ, Guenthoer J, Geng LN, Mahoney SE, Marotta M, Olson JM, Tanaka H, Tapscott SJ. DNA methylation of developmental genes in pediatric medulloblastomas identified by denaturation analysis of methylation differences.
Proc. Natl. Acad. Sci. U.S.A. Dec 4 [Epub ahead of print] (2009).
*
-
Diehl AM. Role of the immune system in the pathogenesis of nonalcoholic steatohepatitis.
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 78 (2005). *
-
Diehl C, Lipozencic J, Ledic-Drvar D. The basis of topical superoxide dismutase antipruritic activity.
Acta Dermatovenerol. Croat. 17: 25-39 (2009).
-
Dieker J, Muller S. Epigenetic histone code and autoimmunity.
Clin. Rev. Allergy Immunol. Aug 7 [Epub ahead of print] (2009).
*
-
Dieleman LA, Elson CO, Tennyson GS, Beagley KW. Kinetics of cytokine expression during healing of acute colitis in mice.
Am. J. Physiol. 271: G130-G136 (1996).
-
Dieplinger B, Schiefermeier N, Juchum-Pasquazzo M, Gstir R, Huber LA, Klimaschewski L, Vietor I. The transcriptional corepressor TPA-inducible sequence 7 regulates adult axon growth through cellular retinoic acid binding protein II expression.
Eur. J. Neurosci. 26: 3358-3367 (2007).
-
Diepstra A, Poppema S, Boot M, Visser L, Nolte IM, Niens M, Te Meerman GJ, van den Berg A. HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin's lymphoma.
Tissue Antigens 71: 219-226 (2008).
*
-
Diestel A, Berger F, Schmitt K. Hypothermia downregulates inflammation but enhances IL-6 secretion by stimulated endothelial cells.
Cryobiology 57: 216-222 (2008).
-
Dieter MZ, Maher JM, Cheng X, Klaassen CD. Expression and regulation of the sterol half-transporter genes ABCG5 and ABCG8 in rats.
Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 139: 209-218 (2004).
*
-
Dieterich W, Esslinger B, Schuppan D. Pathomechanisms in celiac disease.
Int. Arch. Allergy Immunol. 132: 98-108 (2003).
-
Dietrich CG, Geier A, Oude Elferink RP. ABC of oral bioavailability: transporters as gatekeepers in the gut.
Gut 52: 1788-1795 (2003).
*
-
Dieude P. Rheumatic diseases: environment and genetics.
Joint Bone Spine 76: 602-607 (2009).
*
-
Dieude P, Guedj M, Wipff J, Avouac J, Fajardy I, Diot E, Granel B, Sibilia J, Cabane J, Mouthon L, Cracowski JL, Carpentier PH, Hachulla E, Meyer O, Kahan A, Boileau C, Allanore Y. Association between the IRF5 rs2004640 functional polymorphism and systemic sclerosis: a new perspective for pulmonary fibrosis.
Arthritis Rheum. 60: 225-233 (2009).
*
-
Diez M, Abdelmagid N, Harnesk K, Strom M, Lidman O, Swanberg M, Lindblom R, Al-Nimer F, Jagodic M, Olsson T, Piehl F. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury.
J. Neuroimmunol. 212: 82-92 (2009).
-
Dif N, Euthine V, Gonnet E, Laville M, Vidal H, Lefai E. Insulin activates human sterol regulatory element-binding protein-1c (SREBP-1c) promoter through SRE motifs.
Biochem. J. 400: 179-188 (2006).
*
-
Difedele LM, He J, Bonkowski EL, Han X, Held MA, Bohan A, Menon RK, Denson LA. Tumor necrosis factor alpha blockade restores growth hormone signaling in murine colitis.
Gastroenterology 128: 1278-1291 (2005).
*
-
Digby JE, McNeill E, Dyar OJ, Lam V, Greaves DR, Choudhury RP. Anti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and upregulation of adiponectin.
Atherosclerosis Aug 31 [Epub ahead of print] (2009).
-
Dijkhuis AJ, Klappe K, Kamps W, Sietsma H, Kok JW. Gangliosides do not affect ABC transporter function in human neuroblastoma cells.
J. Lipid Res. 47: 1187-1195 (2006).
*
-
Dijkstra G, Blokzijl H, Bok L, Homan M, van Goor H, Nico Faber K, Jansen PL, Moshage H. Opposite effect of oxidative stress on inducible nitric oxide synthase and haem oxygenase-1 expression in intestinal inflammation: anti-inflammatory effect of carbon monoxide.
J. Pathol. 204: 296-303 (2004).
*
-
Dijkstra G, Moshage H, Jansen PL. Blockade of NF-kappaB activation and donation of nitric oxide: new treatment options in inflammatory bowel disease?
Scand. J. Gastroenterol. Suppl. 236: 37-41 (2002).
*
-
Dijkstra G, Yuvaraj S, Jiang HQ, Bun JC, Moshage H, Kushnir N, Peppelenbosch MP, Cebra JJ, Bos NA. Early bacterial dependent induction of inducible nitric oxide synthase (iNOS) in epithelial cells upon transfer of CD45RB(high) CD4(+) T cells in a model for experimental colitis.
Inflamm. Bowel Dis. 13: 1467-1474 (2007).
*
-
Dijstelbloem HM, Scheepers RH, Oost WW, Stegeman CA, van der Pol WL, Sluiter WJ, Kallenberg CG, van de Winkel JG, Tervaert JW. Fcgamma receptor polymorphisms in Wegener's granulomatosis: risk factors for disease relapse.
Arthritis Rheum. 42: 1823-1827 (1999).
*
-
Dilger K, Cascorbi I, Grunhage F, Hohenester S, Sauerbruch T, Beuers U. Multidrug resistance 1 genotype and disposition of budesonide in early primary biliary cirrhosis.
Liver Int. 26: 285-290 (2006).
*
-
Diluvio L, Vollmer S, Besgen P, Ellwart JW, Chimenti S, Prinz JC. Identical TCR beta-chain rearrangements in streptococcal angina and skin lesions of patients with psoriasis vulgaris.
J. Immunol. 176: 7104-7111 (2006).
*
-
DiMagno MJ, Lee SH, Hao Y, Zhou Sy, McKenna BJ, Owyang C. A proinflammatory, anti-apoptotic phenotype underlies the susceptibility to acute pancreatitis in UNC cftr (-/-) mice.
Gastroenterology 129: 665-681 (2005).
*
-
Dimberg J, Dienus O, Lofgren S, Hugander A, Wagsater D. Expression and gene polymorphisms of the chemokine CXCL5 in colorectal cancer patients.
Int. J. Oncol. 31: 97-102 (2007).
*
-
Dimicoli S, Bensoussan D, Latger-Cannard V, Straczek J, Antunes L, Mainard L, Dao A, Barbe F, Araujo C, Clement L, Feugier P, Lecompte T, Stoltz JF, Bordigoni P. Complete recovery from Cryptosporidium parvum infection with gastroenteritis and sclerosing cholangitis after successful bone marrow transplantation in two brothers with X-linked hyper-IgM syndrome.
Bone Marrow Transplant. 32: 733-737 (2003).
*
-
Dimri M, Bommi P, Sahasrabuddhe AA, Khandekar JD, Dimri GP. Dietary omega-3 polyunsaturated fatty acids suppress expression of EZH2 in breast cancer cells.
Carcinogenesis Dec 7 [Epub ahead of print] (2009).
*
-
Dinarello CA. Anti-cytokine therapy from the bench to the bedside.
Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, pp. 84-86 (2005). *
-
Dinarello CA. The IL-1 family and inflammatory diseases.
Clin. Exp. Rheumatol. 20 (5 Suppl. 27): S1-S13 (2002).
-
Ding B, Kirkiles-Smith NC, Pober JS. FOXO3A regulates oxygen-responsive expression of tumor necrosis factor receptor 2 in human dermal microvascular endothelial cells.
J. Biol. Chem. 284: 19331-19339 (2009).
*
-
Ding C, Parsa L, Nandoskar P, Zhao P, Wu K, Wang Y. Duct system of the rabbit lacrimal gland: structural characteristics and its role in lacrimal secretion.
Invest. Ophthalmol. Vis. Sci. Jan 27 [Epub ahead of print] (2010).
-
Ding J, Song D, Ye X, Liu SF. A pivotal role of endothelial-specific NF-kappaB signaling in the pathogenesis of septic shock and septic vascular dysfunction.
J. Immunol. 183: 4031-4038 (2009).
-
Ding J, Woo JT, Nagai K. The effects of retinoic acid on reversing the adipocyte differentiation into an osteoblastic tendency in ST2 cells, a murine bone marrow-derived stromal cell line.
Cytotechnology 36: 125-136 (2001).
*
-
Ding JX, Xu LX, Zhu L, Lv JC, Zhao MH, Zhang H, Wang HY. Activity of alpha2,6-sialyltransferase and its gene expression in peripheral B lymphocytes in patients with IgA nephropathy.
Scand. J. Immunol. 69: 174-180 (2009).
*
-
Ding L, Liang X, Zhu D, Lou Y. Peroxisome proliferator-activated receptor alpha is involved in cardiomyocyte differentiation of murine embryonic stem cells in vitro.
Cell Biol. Int. 31: 1002-1009 (2007).
*
-
Ding SZ, O'hara AM, Denning TL, Dirden-Kramer B, Mifflin RC, Reyes VE, Ryan KA, Elliott SN, Izumi T, Boldogh I, Mitra S, Ernst PB, Crowe SE. Helicobacter pylori and H2O2 increase AP endonuclease-1/redox factor-1 expression in human gastric epithelial cells.
Gastroenterology 127: 845-858 (2004).
*
-
Ding SZ, Torok AM, Smith MF Jr, Goldberg JB. Toll-like receptor 2-mediated gene expression in epithelial cells during Helicobacter pylori infection.
Helicobacter 10: 193-204 (2005).
*
-
Ding W, Mouzaki M, You H, Laird JC, Mato J, Lu SC, Rountree CB. CD133(+) liver cancer stem cells from methionine adenosyl transferase 1A-deficient mice demonstrate resistance to transforming growth factor (TGF)-beta-induced apoptosis.
Hepatology 49: 1277-1286 (2009).
*
-
Ding X, Lichti K, Kim I, Gonzalez FJ, Staudinger JL. Regulation of constitutive androstane receptor and its target genes by fasting, cAMP, hepatocyte nuclear factor alpha, and the coactivator peroxisome proliferator-activated receptor gamma coactivator-1alpha.
J. Biol. Chem. 281: 26540-26551 (2006).
*
-
Ding X, Lichti K, Staudinger JL. The mycoestrogen zearalenone induces CYP3A through activation of the pregnane X receptor.
Toxicol. Sci. 91: 448-455 (2006).
*
-
Ding X, Staudinger J. Induction of drug metabolism by forskolin, the role of the pregnane X receptor and the protein kinase A signal transduction pathway.
J. Pharmacol. Exp. Ther. 312: 849-856 (2005).
*
-
Ding X, Staudinger JL. The ratio of constitutive androstane receptor to pregnane X receptor determines the activity of guggulsterone against the Cyp2b10 promoter.
J. Pharmacol. Exp. Ther. 314: 120-127 (2005).
*
-
Ding X, Staudinger JL. Repression of PXR-mediated induction of hepatic CYP3A gene expression by protein kinase C.
Biochem. Pharmacol. 69: 867-873 (2005).
*
-
Ding Y, Chen D, Tarcsafalvi A, Su R, Qin L, Bromberg JS. Suppressor of cytokine signaling 1 inhibits IL-10-mediated immune responses.
J. Immunol. 170: 1383-1391 (2003).
*
-
Ding Y, Huang Y, Song N, Gao X, Yuan S, Wang X, Cai H, Fu Y, Luo Y. NFAT1 mediates placental growth factor-induced myelomonocytic cell recruitment via the induction of TNF-alpha.
J. Immunol. Jan 22 [Epub ahead of print] (2010).
-
Ding Y, Shen S, Lino AC, Curotto de Lafaille MA, Lafaille JJ. Beta-catenin stabilization extends regulatory T cell survival and induces anergy in nonregulatory T cells.
Nat. Med. 14: 162-169 (2008).
*
-
Ding Z, Maubach G, Masamune A, Zhuo L. Glial fibrillary acidic protein promoter targets pancreatic stellate cells.
Dig. Liver Dis. 41: 229-236 (2009).
-
Dion MF, Altschuler SJ, Wu LF, Rando OJ. Genomic characterization reveals a simple histone H4 acetylation code.
Proc. Natl. Acad. Sci. U.S.A. 102: 5501-5506 (2005).
*
-
Dionne S, Hiscott J, D'Agata I, Duhaime A, Seidman EG. Quantitative PCR analysis of TNF-alpha and IL-1 beta mRNA levels in pediatric IBD mucosal biopsies.
Dig. Dis. Sci. 42: 1557-1566 (1997).
*
-
Dionne S, Levy E, Levesque D, Seidman EG. PPARgamma ligand 15-deoxy-delta 12,14-prostaglandin J2 sensitizes human colon carcinoma cells to TWEAK-induced apoptosis.
Anticancer Res. 30: 157-166 (2010).
-
Diosdado B, Monsuur AJ, Mearin ML, Mulder C, Wijmenga C. The downstream modulator of interferon-gamma, STAT1 is not genetically associated to the Dutch coeliac disease population.
Eur. J. Hum. Genet. 14: 1120-1124 (2006).
*
-
Diosdado B, Stepniak DT, Monsuur AJ, Franke L, Wapenaar MC, Mearin ML, Koning F, Wijmenga C. No genetic association of the human prolyl endopeptidase gene found in the Dutch celiac disease population.
Am. J. Physiol. Gastrointest. Liver Physiol. 289: G495-G500 (2005).
*
-
Diosdado B, van Bakel H, Strengman E, Franke L, van Oort E, Mulder CJ, Wijmenga C, Wapenaar MC. Neutrophil recruitment and barrier impairment in celiac disease: a genomic study.
Clin. Gastroenterol. Hepatol. 5: 574-581.e5 (2007).
-
Diosdado B, Wapenaar MC, Franke L, Duran KJ, Goerres MJ, Hadithi M, Crusius JB, Meijer JW, Duggan DJ, Mulder CJ, Holstege FC, Wijmenga C. A microarray screen for novel candidate genes in coeliac disease pathogenesis.
Gut 53: 944-951 (2004).
*
-
Dipaolo RJ, Brinster C, Davidson TS, Andersson J, Glass D, Shevach EM. Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells.
J. Immunol. 179: 4685-4693 (2007).
*
-
DiRenzo J, Soderstrom M, Kurokawa R, Ogliastro MH, Ricote M, Ingrey S, Horlein A, Rosenfeld MG, Glass CK. Peroxisome proliferator-activated receptors and retinoic acid receptors differentially control the interactions of retinoid X receptor heterodimers with ligands, coactivators, and corepressors.
Mol. Cell. Biol. 17: 2166-2176 (1997).
*
-
Dirkx R, Vanhorebeek I, Martens K, Schad A, Grabenbauer M, Fahimi D, Declercq P, Van Veldhoven PP, Baes M. Absence of peroxisomes in mouse hepatocytes causes mitochondrial and ER abnormalities.
Hepatology 41: 868-878 (2005).
*
-
Dirosario J, Divers E, Wang C, Etter J, Charrier A, Jukkola P, Auer H, Best V, Newsom DL, McCarty DM, Fu H. Innate and adaptive immune activation in the brain of MPS IIIB mouse model.
J. Neurosci. Res. 87: 978-990 (2009).
-
Distante S, Berg JP, Lande K, Haug E, Bell H. HFE gene mutation (C282Y) and phenotypic expression among a hospitalised population in a high prevalence area of haemochromatosis.
Gut 47: 575-579 (2000).
*
-
Distler JH, Jungel A, Kowal-Bielecka O, Michel BA, Gay RE, Sprott H, Matucci-Cerinic M, Chilla M, Reich K, Kalden JR, Muller-Ladner U, Lorenz HM, Gay S, Distler O. Expression of interleukin-21 receptor in epidermis from patients with systemic sclerosis.
Arthritis Rheum. 52: 856-864 (2005).
*
-
Divangahi M, Balghi H, Danialou G, Comtois AS, Demoule A, Ernest S, Haston C, Robert R, Hanrahan JW, Radzioch D, Petrof BJ. Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice.
PLoS Genet. 5: e1000586 (2009).
*
-
Dixit SG, Tirona RG, Kim RB. Beyond CAR and PXR.
Curr. Drug Metab. 6: 385-397 (2005).
-
Dixon AL, Liang L, Moffatt MF, Chen W, Heath S, Wong KC, Taylor J, Burnett E, Gut I, Farrall M, Lathrop GM, Abecasis GR, Cookson WO. A genome-wide association study of global gene expression.
Nat. Genet. 39: 1202-1207 (2007).
*
-
Djerbi M, Malinowski MM, Yagita H, Zhivotovsky B, Grandien A. Participation of FLIP, RIP and Bcl-x(L) in Fas-mediated T-cell Death.
Scand. J. Immunol. 66: 410-421 (2007).
*
-
Djilali-Saiah I, Fakhfakh A, Louafi H, Caillat-Zucman S, Debray D, Alvarez F. HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis.
J. Hepatol. 45: 844-850 (2006).
*
-
Djouadi F, Aubey F, Schlemmer D, Bastin J. Peroxisome proliferator activated receptor delta (PPARdelta) agonist but not PPARalpha corrects carnitine palmitoyl transferase 2 (CPT2) deficiency in human muscle cells.
J. Clin. Endocrinol. Metab. 90: 1791-1797 (2005).
*
-
Djouadi F, Bonnefont JP, Thuillier L, Droin V, Khadom N, Munnich A, Bastin J. Correction of fatty acid oxidation in carnitine palmitoyl transferase 2-deficient cultured skin fibroblasts by bezafibrate.
Pediatr. Res. 54: 446-451 (2003).
*
-
Djouadi F, Lecarpentier Y, Hebert JL, Charron P, Bastin J, Coirault C. A potential link between PPAR signaling and the pathogenesis of arrhythmogenic right ventricular cardiomyopathy (ARVC).
Cardiovasc. Res. 84: 83-90 (2009).
-
Dlugosova K, Weismann P, Bernatova I, Sotnikova R, Slezak J, Okruhlicova L. Omega-3 fatty acids and atorvastatin affect connexin 43 expression in the aorta of hereditary hypertriglyceridemic rats.
Can. J. Physiol. Pharmacol. 87: 1074-1082 (2009).
-
Dmitriev O, Tsivkovskii R, Abildgaard F, Morgan CT, Markley JL, Lutsenko S. Solution structure of the N-domain of Wilson disease protein: distinct nucleotide-binding environment and effects of disease mutations.
Proc. Natl. Acad. Sci. U.S.A. 103: 5302-5307 (2006).
*
-
Do JE, Kwon SY, Park S, Lee ES. Effects of vitamin D on expression of Toll-like receptors of monocytes from patients with Behcet's disease.
Rheumatology (Oxford) 47: 840-848 (2008).
*
-
Do JS, Fink PJ, Li L, Spolski R, Robinson J, Leonard WJ, Letterio JJ, Min B. Cutting edge: spontaneous development of IL-17-producing gammadelta T cells in the thymus occurs via a TGF-beta1-dependent mechanism.
J. Immunol. Jan 8 [Epub ahead of print] (2010).
-
Doan T, McNally A, Thomas R, Steptoe RJ. Steady-state dendritic cells continuously inactivate T cells that escape thymic negative selection.
Immunol. Cell Biol. 87: 615-622 (2009).
*
-
Dobreva ZG, Stanilova SA, Miteva LD. Differences in the inducible gene expression and protein production of IL-12p40, IL-12p70 and IL-23: involvement of p38 and JNK kinase pathways.
Cytokine 43: 76-82 (2008).
-
Dobreva ZG, Stanilova SA, Miteva LD. The influence of JNK and P38 MAPK inhibition on IL-12P40 and IL-23 production depending on IL12B promoter polymorphism.
Cell. Mol. Biol. Lett. 14: 609-621 (2009).
-
Dobromylskyj M, Ellis S. Complexity in cattle KIR genes: transcription and genome analysis.
Immunogenetics 59: 463-472 (2007).
*
-
Dobrovolskaia MA, Kozlov SV. Inflammation and cancer: when NF-kappaB amalgamates the perilous partnership.
Curr. Cancer Drug Targets 5: 325-344 (2005).
-
Dobrovolskaia MA, Medvedev AE, Thomas KE, Cuesta N, Toshchakov V, Ren T, Cody MJ, Michalek SM, Rice NR, Vogel SN. Induction of in vitro reprogramming by Toll-like receptor (TLR)2 and TLR4 agonists in murine macrophages: effects of TLR "homotolerance" versus "heterotolerance" on NF-kappa B signaling pathway components.
J. Immunol. 170: 508-519 (2003).
*
-
Dobrzynski E, Fitzgerald JC, Cao O, Mingozzi F, Wang L, Herzog RW. Prevention of cytotoxic T lymphocyte responses to factor IX-expressing hepatocytes by gene transfer-induced regulatory T cells.
Proc. Natl. Acad. Sci. U.S.A. 103: 4592-4597 (2006).
*
-
Dodge JC, Clarke J, Song A, Bu J, Yang W, Taksir TV, Griffiths D, Zhao MA, Schuchman EH, Cheng SH, O'Riordan CR, Shihabuddin LS, Passini MA, Stewart GR. Gene transfer of human acid sphingomyelinase corrects neuropathology and motor deficits in a mouse model of Niemann-Pick type A disease
Proc. Natl. Acad. Sci. U.S.A. 102: 17822-17827 (2005).
*
-
Dodge R, Loomans C, Sharma A, Bonner-Weir S. Developmental pathways during in vitro progression of human islet neogenesis.
Differentiation 77: 135-147 (2009).
*
-
Dodon MD, Li Z, Hamaia S, Gazzolo L. Tax protein of human T-cell leukaemia virus type 1 induces interleukin 17 gene expression in T cells.
J. Gen. Virol. 85: 1921-1932 (2004).
*
-
Doebis C, Schu S, Ladhoff J, Busch A, Beyer F, Reiser J, Nicosia RF, Broesel S, Volk HD, Seifert M. An anti-major histocompatibility complex class I intrabody protects endothelial cells from an attack by immune mediators.
Cardiovasc. Res. 72: 331-338 (2006).
*
-
Dogan RN, Elhofy A, Karpus WJ. Production of CCL2 by central nervous system cells regulates development of murine experimental autoimmune encephalomyelitis through the recruitment of TNF- and iNOS-expressing macrophages and myeloid dendritic cells.
J. Immunol. 180: 7376-7384 (2008).
*
-
Doganci A, Neurath MF, Finotto S. Mucosal immunoregulation: transcription factors as possible therapeutic targets.
Curr. Drug Targets Inflamm. Allergy 4: 565-575 (2005).
-
Doger FK, Dikicioglu E, Ergin F, Unal E, Sendur N, Uslu M. Nature of cell kinetics in psoriatic epidermis.
J. Cutan. Pathol. 34: 257-263 (2007).
*
-
Dogra N, Warburton C, McMaster WR. Leishmania major abrogates gamma interferon-induced gene expression in human macrophages from a global perspective.
Infect. Immun. 75: 3506-3515 (2007).
*
-
Dohi T, Borodovsky A, Wu P, Shearstone JR, Kawashima R, Runkel L, Rajman L, Dong X, Scott ML, Michaelson JS, Jakubowski A, Burkly LC. TWEAK/Fn14 pathway: a nonredundant role in intestinal damage in mice through a TWEAK/intestinal epithelial cell axis.
Gastroenterology 136: 912-923.e8 (2009).
*
-
Doisne JM, Castaigne JG, Deruyffelaere C, Dieu-Nosjean MC, Chamot C, Alcaide-Loridan C, Charron D, Al-Daccak R. The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes.
Mol. Immunol. 45: 709-718 (2008).
*
-
Dolan BP, Li L, Takeda K, Bennink JR, Yewdell JW. Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase.
J. Immunol. Dec 28 [Epub ahead of print] (2009).
-
Dolis D, Moreau C, Zachowski A, Devaux PF. Aminophospholipid translocase and proteins involved in transmembrane phospholipid traffic.
Biophys. Chem. 68: 221-231 (1997).
-
Dolle P. Developmental expression of retinoic acid receptors (RARs).
Nucl. Recept. Signal. 7: e006 (2009).
*
-
Dolle P, Ruberte E, Kastner P, Petkovich M, Stoner CM, Gudas LJ, Chambon P. Differential expression of genes encoding alpha, beta and gamma retinoic acid receptors and CRABP in the developing limbs of the mouse.
Nature 342: 702-705 (1989).
*
-
Domberg J, Chao L, Papewalis C, Pfleger C, Xu K, Willenberg HS, Hermsen D, Scherbaum WA, Schloot NC, Schott M. Circulating chemokines in patients with autoimmune thyroid diseases.
Horm. Metab. Res. 40: 416-421 (2008).
-
Domenicali M, Caraceni P, Giannone F, Baldassarre M, Lucchetti G, Quarta C, Patti C, Catani L, Nanni C, Lemoli RM, Bernardi M. A novel model of CCl(4)-induced cirrhosis with ascites in the mouse.
J. Hepatol. 51: 991-999 (2009).
-
Dominguez-Soto A, Aragoneses-Fenoll L, Gomez-Aguado F, Corcuera MT, Claria J, Garcia-Monzon C, Bustos M, Corbí AL. The pathogen receptor liver and lymph node sinusoidal endotelial cell C-type lectin is expressed in human Kupffer cells and regulated by PU.1.
Hepatology 49: 287-296 (2009).
*
-
Dominguez-Soto A, Relloso M, Vega MA, Corbi AL, Puig-Kroger A. RUNX3 regulates the activity of the CD11a and CD49d integrin gene promoters.
Immunobiology 210: 133-139 (2005).
-
Dommels YE, Butts CA, Zhu S, Davy M, Martell S, Hedderley D, Barnett MP, McNabb WC, Roy NC. Characterization of intestinal inflammation and identification of related gene expression changes in mdr1a(-/-) mice.
Genes Nutr. 2: 209-223 (2007).
*
-
Dona M, Fredman G, Schwab JM, Chiang N, Arita M, Goodarzi A, Cheng G, von Andrian UH, Serhan CN. Resolvin E1, an EPA-derived mediator in whole blood, selectively counterregulates leukocytes and platelets.
Blood 112: 848-855 (2008).
*
-
Donaghue KC, Margan SH, Chan AK, Holloway B, Silink M, Rangel T, Bennetts B. The association of aldose reductase gene (AKR1B1) polymorphisms with diabetic neuropathy in adolescents.
Diabet. Med. 22: 1315-1320 (2005).
*
-
Donaldson PT. Chapter 17. Immunogenetics of autoimmune liver disease: risk factors for susceptibility and progression.
In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 221-234 (2007). *
-
Donaldson PT. Immunogenetics in liver diseases.
Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 23-24. September 12 - 13 (2003). *
-
Donaldson PT, Czaja AJ. Genetic effects on susceptibility, clinical expression, and treatment outcome of type 1 autoimmune hepatitis.
Clin. Liver Dis. 6: 419-437 (2002).
-
Donato AJ, Black AD, Jablonski KL, Gano LB, Seals DR. Aging is associated with greater nuclear NFkappaB, reduced IkappaBalpha and increased expression of proinflammatory cytokines in vascular endothelial cells of healthy humans.
Aging Cell 7: 805-812 (2008).
-
Donato LJ, Suh JH, Noy N. Suppression of mammary carcinoma cell growth by retinoic acid: the cell cycle control gene Btg2 is a direct target for retinoic acid receptor signaling.
Cancer Res. 67: 609-615 (2007).
*
-
Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, Moore DD. Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease.
Proc. Natl. Acad. Sci. U.S.A. 106: 18831-18836 (2009).
*
-
Dong C. Regulation and pro-inflammatory function of interleukin-17 family cytokines.
Immunol. Rev. 226: 80-86 (2008).
*
-
Dong DM, Yao M, Liu B, Sun CY, Jiang YQ, Wang YS. Association between the -1306C/T polymorphism of matrix metalloproteinase-2 gene and lumbar disc disease in Chinese young adults.
Eur. Spine J. 16: 1958-1961 (2007).
*
-
Dong H, Yauk CL, Williams A, Lee A, Douglas GR, Wade MG. Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid responsive element.
Endocrinology 148: 3932-3940 (2007).
*
-
Dong HD, Chen XM. Immunoregulatory role of B7-H1 in chronicity of inflammatory responses.
Cell. Mol. Immunol. 3: 179-187 (2006).
*
-
Dong HY, Shao JW, Chen JF, Wang T, Lin FP, Guo YH. Transcriptional regulation of cytochrome P450 3A4 by four kinds of traditional Chinese medicines.
Zhongguo Zhong Yao Za Zhi 33: 1014-1017, 1089 (2008).
-
Dong J, Lai R, Nielsen K, Fekete CA, Qiu H, Hinnebusch AG. The essential ATP-binding cassette protein RLI1 functions in translation by promoting preinitiation complex assembly.
J. Biol. Chem. 279: 42157-42168 (2004).
*
-
Dong J, Wang QX, Zhou CY, Ma XF, Zhang YC. Activation of the STAT1 signalling pathway in lupus nephritis in MRL/lpr mice.
Lupus 16: 101-109 (2007).
*
-
Dong L, Wang S, Chen M, Li H, Bi W. The activation of macrophage and upregulation of CD40 costimulatory molecule in lipopolysaccharide-induced acute lung injury.
J. Biomed. Biotechnol. 2008: 852571 (2008).
*
-
Dong LW, Kong XN, Yan HX, Yu LX, Chen L, Yang W, Liu Q, Huang DD, Wu MC, Wang HY. Signal regulatory protein alpha negatively regulates both TLR3 and cytoplasmic pathways in type I interferon induction.
Mol. Immunol. 45: 3025-3035 (2008).
*
-
Dong P, Tao Y, Yang Y, Wang W. Expression of retinoic acid receptors in intestinal mucosa and the effect of vitamin A on mucosal immunity.
Nutrition Nov 19 [Epub ahead of print] (2009).
-
Dong X, Zhou G, Zhai Y, Zhang H, Yang H, Zhi L, Zhang X, Chu J, He F. Association of DLC1 gene polymorphism with susceptibility to hepatocellular carcinoma in Chinese hepatitis B virus carriers.
Cancer Epidemiol. 33: 265-270 (2009).
-
Dong YW, Wang XP, Wu K. Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition.
World J. Gastroenterol. 15: 441-448 (2009).
*
-
Dongiovanni P, Fracanzani AL, Cairo G, Megazzini CP, Gatti S, Rametta R, Fargion S, Valenti L. Iron-dependent regulation of MDM2 influences p53 activity and hepatic carcinogenesis.
Am. J. Pathol. Dec 17 [Epub ahead of print] (2009).
*
-
Doni A, Mantovani G, Porta C, Tuckermann J, Reichardt HM, Kleiman A, Sironi M, Rubino L, Pasqualini F, Nebuloni M, Signorini S, Peri G, Sica A, Beck-Peccoz P, Bottazzi B, Mantovani A. Cell-specific regulation of PTX3 by glucocorticoid hormones in hematopoietic and non-hematopoietic cells.
J. Biol. Chem. 283: 29983-29992 (2008).
*
-
Donkor J, Sparks LM, Xie H, Smith SR, Reue K. Adipose tissue lipin-1 expression is correlated with PPARalpha gene expression and insulin sensitivity in healthy young men.
J. Clin. Endocrinol. Metab. 93: 233-239 (2008).
*
-
Donner MG, Schumacher S, Warskulat U, Heinemann J, Haussinger D. Obstructive cholestasis induces TNF-alpha- and IL-1beta-mediated periportal down-regulation of Bsep and zonal regulation of Ntcp, Oatp1a4 and Oatp1b2.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G1134-G1146 (2007).
*
-
Donson AM, Birks DK, Barton VN, Wei Q, Kleinschmidt-Demasters BK, Handler MH, Waziri A, Wang M, Foreman NK. Immune gene and cell enrichment is associated with a good prognosis in ependymoma.
J. Immunol. 183: 7428-7440 (2009).
-
Doodes PD, Cao Y, Hamel KM, Wang Y, Rodeghero RL, Mikecz K, Glant TT, Iwakura Y, Finnegan A. IFN-gamma regulates the requirement for IL-17 in proteoglycan-induced arthritis.
J. Immunol. Dec 18 [Epub ahead of print] (2009).
-
Doody KM, Bourdeau A, Tremblay ML. T-cell protein tyrosine phosphatase is a key regulator in immune cell signaling: lessons from the knockout mouse model and implications in human disease.
Immunol. Rev. 228: 325-341 (2009).
*
-
Dooley J, Erickson M, Farr AG. Lessons from thymic epithelial heterogeneity: FoxN1 and tissue-restricted gene expression by extrathymic, endodermally derived epithelium.
J. Immunol. 183: 5042-5049 (2009).
-
Dooley TP, Curto EV, Reddy SP, Davis RL, Lambert GW, Wilborn TW, Elson CO. Regulation of gene expression in inflammatory bowel disease and correlation with IBD drugs: screening by DNA microarrays.
Inflamm. Bowel Dis. 10: 1-14 (2004).
*
-
Dooms H, Wolslegel K, Lin P, Abbas AK. Interleukin-2 enhances CD4+ T cell memory by promoting the generation of IL-7R alpha-expressing cells.
J. Exp. Med. 204: 547-557 (2007).
*
-
Doonan F, Wallace DM, O'Driscoll C, Cotter TG. Rosiglitazone acts as a neuro-protectant in retinal cells via up-regulation of sestrin-1 and SOD-2.
J. Neurochem. 109: 631-643 (2009).
-
Dorfman R, Sandford A, Taylor C, Huang B, Frangolias D, Wang Y, Sang R, Pereira L, Sun L, Berthiaume Y, Tsui LC, Pare PD, Durie P, Corey M, Zielenski J. Complex two-gene modulation of lung disease severity in children with cystic fibrosis.
J. Clin. Invest. 118: 1040-1049 (2008).
*
-
Dorfmeister B, Brandlhofer S, Schaap FG, Hermann M, Furnsinn C, Hagerty BP, Stangl H, Patsch W, Strobl W. Apolipoprotein AV does not contribute to hypertriglyceridaemia or triglyceride lowering by dietary fish oil and rosiglitazone in obese Zucker rats.
Diabetologia 49: 1324-1332 (2006).
*
-
Dorin JR, Stevenson BJ, Fleming S, Alton EW, Dickinson P, Porteous DJ. Long-term survival of the exon 10 insertional cystic fibrosis mutant mouse is a consequence of low level residual wild-type Cftr gene expression.
Mamm. Genome 5: 465-472 (1994).
-
Dorner AJ, Goldman SJ, Keith Jr JC. Interleukin-11.
BioDrugs 8: 418-429 (1997).
-
Dorner M, Brandt S, Tinguely M, Zucol F, Bourquin JP, Zauner L, Berger C, Bernasconi M, Speck RF, Nadal D. Plasma cell Toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production.
Immunology 128: 573-579 (2009).
*
-
Dorner T, Feist E, Wagenmann A, Kato T, Yamamoto K, Nishioka K, Burmester GR, Hiepe F. Anti-52 kDa Ro(SSA) autoantibodies in different autoimmune diseases preferentially recognize epitopes on the central region of the antigen.
J. Rheumatol. 23: 462-468 (1996).
-
Dorwart MR, Shcheynikov N, Baker JM, Forman-Kay JD, Muallem S, Thomas PJ. Congenital chloride-losing diarrhea causing mutations in the STAS domain result in misfolding and mistrafficking of SLC26A3.
J. Biol. Chem. 283: 8711-8722 (2008).
*
-
Dos Santos AC, Roffe E, Arantes RM, Juliano L, Pesquero JL, Pesquero JB, Bader M, Teixeira MM, Carvalho-Tavares J. Kinin B2 receptor regulates chemokines CCL2 and CCL5 expression and modulates leukocyte recruitment and pathology in experimental autoimmune encephalomyelitis (EAE) in mice.
J. Neuroinflammation 5: 49 (2008).
-
Dos Santos Mendes S, Candi A, Vansteenbrugge M, Pignon MR, Bult H, Boudjeltia KZ, Munaut C, Raes M. Microarray analyses of the effects of NFkappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells. Synergistic effects of rapamycin on LPS induced MMP9-overexpression.
Cell Signal. 21: 1109-1122 (2009).
*
-
Dosenko VE, Zagoriy VY, Haytovich NV, Gordok OA, Moibenko AA. Allelic polymorphism of endothelial NO-synthase gene and its functional manifestations.
Acta Biochim. Pol. 53: 299-302 (2006).
*
-
Dotan I, Mayer L. Immunopathogenesis of inflammatory bowel disease.
Curr. Opin. Gastroenterol. 18: 421-427 (2002).
-
Dotsch J, Puls J, Klimek T, Rascher W. Reduction of neuronal and inducible nitric oxide synthase gene expression in patients with cystic fibrosis.
Eur. Arch. Otorhinolaryngol. 259: 222-226 (2002).
-
Dotzlaw H, Eggert M, Neeck G, Schulz M. Spots, blots, peaks and chips: proteomic approaches in autoimmune diseases.
Curr. Pharm. Des. 12: 3699-3706 (2006).
-
Dou J, Wang Y, Wang J, Zhao F, Li Y, Cao M, Hu W, Hu K, He XF, Chu L, Jiang C, Gu N. Antitumor efficacy induced by human ovarian cancer cells secreting IL-21 alone or combination with GM-CSF cytokines in nude mice model.
Immunobiology 214: 483-492 (2009).
-
Douet V, Heller MB, Le Saux O. DNA methylation and Sp1 binding determine the tissue-specific transcriptional activity of the mouse Abcc6 promoter.
Biochem. Biophys. Res. Commun. 354: 66-71 (2007).
*
-
Douet V, Vanwart CM, Heller MB, Reinhard S, Le Saux O. HNF4alpha and NF-E2 are key transcriptional regulators of the murine Abcc6 gene expression.
Biochim. Biophys. Acta 1759: 426-436 (2006).
*
-
Douglas G, Reilly C, Dooley MA, Page G, Cooper G, Gilkeson G. Angiotensin-converting enzyme (insertion/deletion) and endothelial nitric oxide synthase polymorphisms in patients with systemic lupus erythematosus.
J. Rheumatol. 31: 1756-1762 (2004).
-
Douglas RS, Naik V, Hwang CJ, Afifiyan NF, Gianoukakis AG, Sand D, Kamat S, Smith TJ. B cells from patients with Graves' disease aberrantly express the IGF-1 receptor: implications for disease pathogenesis.
J. Immunol. 181: 5768-5774 (2008).
*
-
Dowds TA, Masumoto J, Chen FF, Ogura Y, Inohara N, Nunez G. Regulation of cryopyrin/Pypaf1 signaling by pyrin, the familial Mediterranean fever gene product.
Biochem. Biophys. Res. Commun. 302: 575-580 (2003).
*
-
Dowds TA, Masumoto J, Zhu L, Inohara N, Nunez G. Cryopyrin-induced interleukin 1beta secretion in monocytic cells: enhanced activity of disease-associated mutants and requirement for ASC.
J. Biol. Chem. 279: 21924-21928 (2004).
*
-
Dower K, Ellis DK, Saraf K, Jelinsky SA, Lin LL. Innate immune responses to TREM-1 activation: overlap, divergence, and positive and negative cross-talk with bacterial lipopolysaccharide.
J. Immunol. 180: 3520-3534 (2008).
*
-
Downes M, Liddle C. Look who's talking: nuclear receptors in the liver and gastrointestinal tract.
Cell Metab. 7: 195-199 (2008).
*
-
Downes M, Verdecia MA, Roecker AJ, Hughes R, Hogenesch JB, Kast-Woelbern HR, Bowman ME, Ferrer JL, Anisfeld AM, Edwards PA, Rosenfeld JM, Alvarez JG, Noel JP, Nicolaou KC, Evans RM. A chemical, genetic, and structural analysis of the nuclear bile acid receptor FXR.
Mol. Cell 11: 1079-1092 (2003).
*
-
Downie MM, Sanders DA, Maier LM, Stock DM, Kealey T. Peroxisome proliferator-activated receptor and farnesoid X receptor ligands differentially regulate sebaceous differentiation in human sebaceous gland organ cultures in vitro.
Br. J. Dermatol. 151: 766-775 (2004).
*
-
Doyle DF, Mangelsdorf DJ, Corey DR. Modifying ligand specificity of gene regulatory proteins.
Curr. Opin. Chem. Biol. 4: 60-63 (2000).
*
-
Doyle LA, Ross DD. Multidrug resistance mediated by the breast cancer resistance protein BCRP (ABCG2).
Oncogene 22: 7340-7358 (2003).
*
-
Doyle SE, Schreckhise H, Khuu-Duong K, Henderson K, Rosler R, Storey H, Yao L, Liu H, Barahmand-Pour F, Sivakumar P, Chan C, Birks C, Foster D, Clegg CH, Wietzke-Braun P, Mihm S, Klucher KM. Interleukin-29 uses a type 1 interferon-like program to promote antiviral responses in human hepatocytes.
Hepatology 44: 896-906 (2006).
*
-
Doyle SL, O'Neill LA. Toll-like receptors: from the discovery of NFkappaB to new insights into transcriptional regulations in innate immunity.
Biochem. Pharmacol. 72: 1102-1113 (2006).
*
-
Doyon G, St-Jean S, Darsigny M, Asselin C, Boudreau F. Nuclear receptor co-repressor is required to maintain proliferation of normal intestinal cells in culture and down-modulates the expression of pigment-epithelial-derived factor.
J. Biol. Chem. 284: 25220-25229 (2009).
*
-
Dozmorov I, Knowlton N, Tang Y, Shields A, Pathipvanich P, Jarvis JN, Centola M. Hypervariable genes - experimental error or hidden dynamics.
Nucleic Acids Res. 32: e147 (2004).
*
-
Dragnev KH, Petty WJ, Dmitrovsky E. Retinoid targets in cancer therapy and chemoprevention.
Cancer Biol. Ther. 2: S150-S156 (2003).
-
Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Sapone AT, Thakar M, Iacono G, Carroccio A, D'Agate C, Not T, Zampini L, Catassi C, Fasano A. Gliadin, zonulin and gut permeability: effects on celiac and non-celiac intestinal mucosa and intestinal cell lines.
Scand. J. Gastroenterol. 41: 408-419 (2006).
*
-
Drake TA, Schadt EE, Lusis AJ. Integrating genetic and gene expression data: application to cardiovascular and metabolic traits in mice.
Mamm. Genome 17: 466-479 (2006).
*
-
Dransfeld O, Gehrmann T, Kohrer K, Kircheis G, Holneicher C, Haussinger D, Wettstein M. Oligonucleotide microarray analysis of differential transporter regulation in the regenerating rat liver.
Liver Int. 25: 1243-1258 (2005).
*
-
Dray C, Daviaud D, Guigne C, Valet P, Castan-Laurell I. Caffeine reduces TNFalpha up-regulation in human adipose tissue primary culture.
J. Physiol. Biochem. 63: 329-336 (2007).
-
Dray-Charier N, Paul A, Scoazec JY, Veissiere D, Mergey M, Capeau J, Soubrane O, Housset C. Expression of delta F508 cystic fibrosis transmembrane conductance regulator protein and related chloride transport properties in the gallbladder epithelium from cystic fibrosis patients.
Hepatology 29: 1624-1634 (1999).
*
-
Dray-Charier N, Paul A, Veissiere D, Mergey M, Scoazec JY, Capeau J, Brahimi-Horn C, Housset C. Expression of cystic fibrosis transmembrane conductance regulator in human gallbladder epithelial cells.
Lab. Invest. 73: 828-836 (1995).
-
Dreijerink KM, Varier RA, van Beekum O, Jeninga EH, Hoppener JW, Lips CJ, Kummer JA, Kalkhoven E, Timmers HT. The multiple endocrine neoplasia type 1 (MEN1) tumor suppressor regulates PPARgamma-dependent adipocyte differentiation.
Mol. Cell Biol. 29: 5060-5069 (2009).
*
-
Dreijerink KM, Varier RA, van Nuland R, Broekhuizen R, Valk GD, van der Wal JE, Lips CJ, Kummer JA, Timmers HT. Regulation of vitamin D receptor function in MEN1-related parathyroid adenomas.
Mol. Cell. Endocrinol. 313: 1-8 (2009).
-
Dresch C, Edelmann SL, Marconi P, Brocker T. Lentiviral-mediated transcriptional targeting of dendritic cells for induction of T cell tolerance in vivo.
J. Immunol. 181: 4495-4506 (2008).
*
-
Dreuw A, Hermanns HM, Heise R, Joussen S, Rodriguez F, Marquardt Y, Jugert F, Merk HF, Heinrich PC, Baron JM. Interleukin-6-type cytokines upregulate expression of multidrug resistance-associated proteins in NHEK and dermal fibroblasts.
J. Invest. Dermatol. 124: 28-37 (2005).
*
-
Drevinek P, Holden MT, Ge Z, Jones AM, Ketchell I, Gill RT, Mahenthiralingam E. Gene expression changes linked to antimicrobial resistance, oxidative stress, iron depletion and retained motility are observed when Burkholderia cenocepacia grows in cystic fibrosis sputum.
BMC Infect. Dis. 8: 121 (2008).
*
-
Drew JE, Farquharson AJ, Arthur JR, Morrice PC, Duthie GG. Novel sites of cytosolic glutathione peroxidase expression in colon.
FEBS Lett. 579: 6135-6139 (2005).
*
-
Dreyer C, Keller H, Mahfoudi A, Laudet V, Krey G, Wahli W. Positive regulation of the peroxisomal beta-oxidation pathway by fatty acids through activation of peroxisome proliferator-activated receptors (PPAR).
Biol. Cell 77: 67-76 (1993).
-
Drinda S, Franke S, Eidner T, Schmidt C, Ruster C, Bondeva T, Hein G, Wolf G. Decreased RAGE expression in peripheral blood mononuclear cells of patients with rheumatoid arthritis.
Clin. Exp. Rheumatol. 27: 483-490 (2009).
-
Dring MM, Goulding CA, Trimble VI, Keegan D, Ryan AW, Brophy KM, Smyth CM, Keeling PWN, O’Donoghue D, O’Sullivan M, O’Morain C, Mahmud N, Wikstrom AC, Kelleher D, McManus R. The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.
Gastroenterology 130: 341-348 (2006).
*
-
Droemann D, Rupp J, Goldmann T, Uhlig U, Branscheid D, Vollmer E, Kujath P, Zabel P, Dalhoff K. Disparate innate immune responses to persistent and acute Chlamydia pneumoniae infection in chronic obstructive pulmonary disease.
Am. J. Respir. Crit. Care Med. 175: 791-797 (2007).
*
-
Drosera M, Facchetti F, Landolfo S, Mondini M, Nyberg F, Parodi A, Santoro A, Zampieri S, Doria A. Role of soluble and cell surface molecules in the pathogenesis of autoimmune skin diseases.
Clin. Exp. Rheumatol. 24: S7-S13 (2006).
-
Drosos AA, Moutsopoulos HM. Rheumatoid arthritis in Greece: clinical, serological and genetic considerations.
Clin. Exp. Rheumatol. 13 Suppl. 12: S7-S12 (1995).
-
Drumm ML, Wilkinson DJ, Smit LS, Worrell RT, Strong TV, Frizzell RA, Dawson DC, Collins FS. Chloride conductance expressed by delta F508 and other mutant CFTRs in Xenopus oocytes.
Science 254: 1797-1799 (1991).
*
-
Du C, Fujii Y, Ito M, Harada M, Moriyama E, Shimada R, Ikemoto A, Okuyama H. Dietary polyunsaturated fatty acids suppress acute hepatitis, alter gene expression and prolong survival of female Long-Evans Cinnamon rats, a model of Wilson disease.
J. Nutr. Biochem. 15: 273-280 (2004).
*
-
Du C, Liu C, Kang J, Zhao G, Ye Z, Huang S, Li Z, Wu Z, Pei G. MicroRNA miR-326 regulates T(H)-17 differentiation and is associated with the pathogenesis of multiple sclerosis.
Nat. Immunol. 10: 1252-1259 (2009).
*
-
DU CQ, Huang MX, Liu WJ. Effect of ATRA on the expression of genes Hoxb2 and Hoxb4 in cord blood erythroid progenitors.
Zhongguo Shi Yan Xue Ye Xue Za Zhi 17: 1516-1521 (2009).
-
Du HQ, Yin M, Ye HY, Shang YJ, Dai XD, Jing W, Zhang L, Xiao N, Li JF, Pan J. Expression profiles of lipid metabolism-related genes in liver of apoE(-/-)/LDLR(-/-) mice.
Zhonghua Bing Li Xue Za Zhi 36: 751-755 (2007).
-
Du J, Huang C, Zhou B, Ziegler SF. Isoform-specific inhibition of RORalpha-mediated transcriptional activation by human FOXP3.
J. Immunol. 180: 4785-4792 (2008).
*
-
Du J, Liang X, Liu Y, Qu Z, Gao L, Han L, Liu S, Cui M, Shi Y, Zhang Z, Yu L, Cao L, Ma C, Zhang L, Chen Y, Sun W. Hepatitis B virus core protein inhibits TRAIL-induced apoptosis of hepatocytes by blocking DR5 expression.
Cell Death Differ. 16: 219-229 (2009).
-
Du M, Keeling KM, Fan L, Liu X, Kovacs T, Sorscher E, Bedwell DM. Clinical doses of amikacin provide more effective suppression of the human CFTR-G542X stop mutation than gentamicin in a transgenic CF mouse model.
J. Mol. Med. 84: 573-582 (2006).
*
-
Du MR, Zhou WH, Yan FT, Zhu XY, He YY, Yang JY, Li DJ. Cyclosporine A induces titin expression via MAPK/ERK signalling and improves proliferative and invasive potential of human trophoblast cells.
Hum. Reprod. 22: 2528-2537 (2007).
*
-
Du S, Hiramatsu N, Hayakawa K, Kasai A, Okamura M, Huang T, Yao J, Takeda M, Araki I, Sawada N, Paton AW, Paton JC, Kitamura M. Suppression of NF-kappaB by cyclosporin A and tacrolimus (FK506) via induction of the C/EBP family: implication for unfolded protein response.
J. Immunol. 182: 7201-7211 (2009).
-
Du XL, Jiang T, Sheng XG, Gao R, Li QS. Inhibition of osteopontin suppresses in vitro and in vivo angiogenesis in endometrial cancer.
Gynecol. Oncol. 115: 371-376 (2009).
-
Du Y, Zhang QY, Ruan LR, Liang CC, Li QR, He W. The relationship between abnormal apoptosis and Fas expression of thymocytes from patients with myasthenia gravis.
Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 19: 450-453 (2003).
-
Du YC, Oshima H, Oguma K, Kitamura T, Itadani H, Fujimura T, Piao YS, Yoshimoto T, Minamoto T, Kotani H, Taketo MM, Oshima M. Induction and downregulation of Sox17 and its possible roles during the course of gastrointestinal tumorigenesis.
Gastroenterology 137: 1346-1357 (2009).
*
-
Duan H, Chai J, Sheng Z, Yao Y, Yin H, Liang L, Shen C, Lin J. Effect of burn injury on apoptosis and expression of apoptosis-related genes/proteins in skeletal muscles of rats.
Apoptosis 14: 52-65 (2009).
*
-
Duan H, Fleming J, Pritchard DK, Amon LM, Xue J, Arnett HA, Chen G, Breen P, Buckner JH, Molitor JA, Elkon KB, Schwartz SM. Combined analysis of monocyte and lymphocyte messenger RNA expression with serum protein profiles in patients with scleroderma.
Arthritis Rheum. 58: 1465-1474 (2008).
*
-
Duan HO, Simpson-Haidaris PJ. Functional analysis of interleukin 6 response elements (IL-6REs) on the human gamma-fibrinogen promoter: binding of hepatic Stat3 correlates negatively with transactivation potential of type II IL-6REs.
J. Biol. Chem. 278: 41270-41281 (2003).
*
-
Duan K, Surette MG. Environmental regulation of Pseudomonas aeruginosa PAO1 Las and Rhl quorum-sensing systems.
J. Bacteriol. 189: 4827-4836 (2007).
*
-
Duan RD. Alkaline sphingomyelinase: an old enzyme with novel implications.
Biochim. Biophys. Acta 1761: 281-291 (2006).
*
-
Duan RS, Jin T, Yang X, Mix E, Adem A, Zhu J. Apolipoprotein E deficiency enhances the antigen-presenting capacity of Schwann cells.
Glia 55: 772-776 (2007).
-
Duan ZX, Zhu PF, Dong H, Gu W, Yang C, Liu Q, Wang ZG, Jiang JX. Functional significance of the TLR4/11367 polymorphism identified in Chinese Han population.
Shock 28: 160-164 (2007).
*
-
Duane WC, Hartich LA, Bartman AE, Ho SB. Diminished gene expression of ileal apical sodium bile acid transporter explains impaired absorption of bile acid in patients with hypertriglyceridemia.
J. Lipid Res. 41: 1384-1389 (2000).
*
-
Duane WC, Xiong W, Lofgren J. Transactivation of the human apical sodium-dependent bile acid transporter gene by human serum.
J. Steroid Biochem. Mol. Biol. 108: 137-148 (2008).
-
Duane WC, Xiong W, Wolvers J. Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene.
Biochim. Biophys. Acta 1771: 1380-1388 (2007).
*
-
Duanmu Z, Locke D, Smigelski J, Wu W, Dahn MS, Falany CN, Kocarek TA, Runge-Morris M. Effects of dexamethasone on aryl (SULT1A1)- and hydroxysteroid (SULT2A1)-sulfotransferase gene expression in primary cultured human hepatocytes.
Drug Metab. Dispos. 30: 997-1004 (2002).
*
-
Duarte PM, Neto JB, Casati MZ, Sallum EA, Nociti FH Jr. Diabetes modulates gene expression in the gingival tissues of patients with chronic periodontitis.
Oral Dis. 13: 594-599 (2007).
-
Duarte WR, Shibata T, Takenaga K, Takahashi E, Kubota K, Ohya K, Ishikawa I, Yamauchi M, Kasugai S. S100A4: a novel negative regulator of mineralization and osteoblast differentiation.
J. Bone Miner. Res. 18: 493-501 (2003).
-
Dubaniewicz A, Dubaniewicz A. Cholangiocarcinoma - bile ducts cancer.
Wiad. Lek. 56: 57-60 (2003).
-
Dubaniewicz A, Dubaniewicz-Wybieralska M, Moszkowska G, Sternau A, Dubaniewicz A. Comparative analysis of DR and DQ alleles occurrence in sarcoidosis and tuberculosis in the same ethnic group: preliminary study.
Sarcoidosis Vasc. Diffuse Lung Dis. 23: 180-189 (2006).
-
Dubben S, Honscheid A, Winkler K, Rink L, Haase H. Cellular zinc homeostasis is a regulator in monocyte differentiation of HL-60 cells by 1alpha,25-dihydroxyvitamin D3.
J. Leukoc. Biol. Jan 20 [Epub ahead of print] (2010).
*
-
Dubeykovskiy A, McWhinney C, Robishaw JD. Runx-dependent regulation of G-protein gamma3 expression in T-cells.
Cell. Immunol. 240: 86-95 (2006).
*
-
Dubinsky MC. Optimizing immunomodulator therapy for inflammatory bowel disease.
Curr. Gastroenterol. Rep. 5: 506-511 (2003).
-
Dubois M, Vantyghem MC, Schoonjans K, Pattou F. Thiazolidinediones in type 2 diabetes. Role of peroxisome proliferator-activated receptor gamma (PPARgamma).
Ann. Endocrinol. (Paris) 63: 511-523 (2002).
-
DuBois RN, Gupta R, Brockman J, Reddy BS, Krakow SL, Lazar MA. The nuclear eicosanoid receptor, PPARgamma, is aberrantly expressed in colonic cancers.
Carcinogenesis 19: 49-53 (1998).
*
-
Dubois SG, Heilbronn LK, Smith SR, Albu JB, Kelley DE, Ravussin E. Decreased expression of adipogenic genes in obese subjects with type 2 diabetes.
Obesity (Silver Spring) 14: 1543-1552 (2006).
*
-
Dubrac S, Lear SR, Ananthanarayanan M, Balasubramaniyan N, Bollineni J, Shefer S, Hyogo H, Cohen DE, Blanche PJ, Krauss RM, Batta AK, Salen G, Suchy FJ, Maeda N, Erickson SK. Role of CYP27A in cholesterol and bile acid metabolism.
J. Lipid Res. 46: 76-85 (2005).
*
-
Dubucquoi S, Janin A, Klein O, Desreumaux P, Quandalle P, Cortot A, Capron M, Colombel JF. Activated eosinophils and interleukin 5 expression in early recurrence of Crohn's disease.
Gut 37: 242-246 (1995).
*
-
Dubuquoy L, Jansson EA, Deeb S, Rakotobe S, Karoui M, Colombel JF, Auwerx J, Pettersson S, Desreumaux P. Impaired expression of peroxisome proliferator-activated receptor gamma in ulcerative colitis.
Gastroenterology 124: 1265-1276 (2003).
*
-
Ducray F, Honnorat J, Lachuer J. DNA microarray technology: principles and applications to the study of neurological disorders.
Rev. Neurol. (Paris) 163: 409-420 (2007).
-
Dudas PL, Mentone S, Greineder CF, Biemesderfer D, Aronson PS. Immunolocalization of anion transporter Slc26a7 in mouse kidney.
Am. J. Physiol. Renal Physiol. 290: F937-F945 (2006).
*
-
Dudda JC, Simon JC, Martin S. Dendritic cell immunization route determines CD8+ T cell trafficking to inflamed skin: role for tissue microenvironment and dendritic cells in establishment of T cell-homing subsets.
J. Immunol. 172: 857-863 (2004).
*
-
Dudler J, Li J, Pagnotta M, Pascual M, von Segesser LK, Vassalli G. Gene transfer of programmed death ligand-1.Ig prolongs cardiac allograft survival.
Transplantation 82: 1733-1737 (2006).
-
Duelli A, Ronnberg E, Waern I, Ringvall M, Kolset SO, Pejler G. Mast cell differentiation and activation is closely linked to expression of genes coding for the serglycin proteoglycan core protein and a distinct set of chondroitin sulfate and heparin sulfotransferases.
J. Immunol. 183: 7073-7083 (2009).
-
Duenas AI, Aceves M, Fernandez-Pisonero I, Gomez C, Orduna A, Crespo MS, Garcia-Rodriguez C. Selective attenuation of Toll-like receptor 2 signaling may explain the atheroprotective effect of sphingosine 1-phosphate.
Cardiovasc. Res. 79: 537-544 (2008).
*
-
Duenas AI, Aceves M, Orduna A, Diaz R, Sanchez Crespo M, Garcia-Rodriguez C. Francisella tularensis LPS induces the production of cytokines in human monocytes and signals via Toll-like receptor 4 with much lower potency than E. coli LPS.
Int. Immunol. 18: 785-795 (2006).
*
-
Duenas AI, Orduna A, Sanchez Crespo M, Garcia-Rodriguez C. Interaction of endotoxins with Toll-like receptor 4 correlates with their endotoxic potential and may explain the proinflammatory effect of Brucella spp. LPS.
Int. Immunol. 16: 1467-1475 (2004).
*
-
Duerr RH. Genome-wide association studies herald a new era of rapid discoveries in inflammatory bowel disease research.
Gastroenterology 132: 2045-2049 (2007).
*
-
Duester G. Keeping an eye on retinoic acid signaling during eye development.
Chem. Biol. Interact. 178: 178-181 (2009).
*
-
Duez H, Chao YS, Hernandez M, Torpier G, Poulain P, Mundt S, Mallat Z, Teissier E, Burton CA, Tedgui A, Fruchart JC, Fievet C, Wright SD, Staels B. Reduction of atherosclerosis by the peroxisome proliferator-activated receptor alpha agonist fenofibrate in mice.
J. Biol. Chem. 277: 48051-48057 (2002).
*
-
Duez H, Fruchart JC, Staels B. PPARS in inflammation, atherosclerosis and thrombosis.
J. Cardiovasc. Risk 8: 187-194 (2001).
-
Duez H, Veen JV, Duhem C, Pourcet B, Touvier T, Fontaine C, Derudas B, Bauge E, Havinga R, Bloks VW, Wolters H, van der Sluijs FH, Vennstrom B, Kuipers F, Staels B. Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
Gastroenterology 135: 689-698.e5 (2008).
*
-
Duffin KC, Chandran V, Gladman DD, Krueger GG, Elder JT, Rahman P. Genetics of psoriasis and psoriatic arthritis: update and future direction.
J. Rheumatol. 35: 1449-1453 (2008).
-
Duffy DL, Montgomery GW, Chen W, Zhao ZZ, Le L, James MR, Hayward NK, Martin NG, Sturm RA. A three-single-nucleotide polymorphism haplotype in intron 1 of OCA2 explains most human eye-color variation.
Am. J. Hum. Genet. 80: 241-252 (2007).
*
-
Dufour CR, Wilson BJ, Huss JM, Kelly DP, Alaynick WA, Downes M, Evans RM, Blanchette M, Giguere V. Genome-wide orchestration of cardiac functions by the orphan nuclear receptors ERRalpha and gamma.
Cell. Metab. 5: 345-356 (2007).
*
-
Dumartin L, Quemener C, Laklai H, Herbert J, Bicknell R, Bousquet C, Pyronnet S, Castronovo V, Schilling MK, Bikfalvi A, Hagedorn M. Netrin-1 mediates early events in pancreatic adenocarcinoma progression, acting on tumor and endothelial cells.
Gastroenterology Jan 14 [Epub ahead of print] (2010).
*
-
Dumasia R, Eagle KA, Kline-Rogers E, May N, Cho L, Mukherjee D. Role of PPAR- gamma agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective.
Curr. Drug Targets Cardiovasc. Haemato. Disord. 5: 377-386 (2005).
-
Dumitriu IE, Bianchi ME, Bacci M, Manfredi AA, Rovere-Querini P. The secretion of HMGB1 is required for the migration of maturing dendritic cells.
J. Leukoc. Biol. 81: 84-91 (2007).
*
-
Dumoulin FL, Reichel C, Sauerbruch T, Spengler U. Semiquantitation of intrahepatic MDR3 mRNA levels by reverse transcription/competitive polymerase chain reaction.
J. Hepatol. 26: 852-856 (1997).
*
-
Dumoutier L, Lejeune D, Colau D, Renauld JC. Cloning and characterization of IL-22 binding protein, a natural antagonist of IL-10-related T cell-derived inducible factor/IL-22.
J. Immunol. 166: 7090-7095 (2001).
*
-
Dumoutier L, Van Roost E, Ameye G, Michaux L, Renauld JC. IL-TIF/IL-22: genomic organization and mapping of the human and mouse genes.
Genes Immun. 1: 488-494 (2000).
*
-
Duncan JG, Fong JL, Medeiros DM, Finck BN, Kelly DP. Insulin-resistant heart exhibits a mitochondrial biogenic response driven by the peroxisome proliferator-activated receptor-alpha/PGC-1alpha gene regulatory pathway.
Circulation 115: 909-917 (2007).
*
-
Duncan RE, Archer MC. Farnesol decreases serum triglycerides in rats: identification of mechanisms including up-regulation of PPARalpha and down-regulation of fatty acid synthase in hepatocytes.
Lipids 43: 619-627 (2008).
-
Duncan RE, Archer MC. Farnesol induces thyroid hormone receptor (THR) beta1 but inhibits THR-mediated signaling in MCF-7 human breast cancer cells.
Biochem. Biophys. Res. Commun. 343: 239-243 (2006).
*
-
Duncan SA, Navas MA, Dufort D, Rossant J, Stoffel M. Regulation of a transcription factor network required for differentiation and metabolism.
Science 281: 692-695 (1998).
*
-
Dunehoo AL, Anderson M, Majumdar S, Kobayashi N, Berkland C, Siahaan TJ. Cell adhesion molecules for targeted drug delivery.
J. Pharm. Sci. 95: 1856-1872 (2006).
*
-
Dunlop TW, Vaisanen S, Frank C, Molnar F, Sinkkonen L, Carlberg C. The human peroxisome proliferator-activated receptor delta gene is a primary target of 1alpha,25-dihydroxyvitamin D(3) and its nuclear receptor.
J. Mol. Biol. 349: 248-260 (2005).
*
-
Dunn SE, Ousman SS, Sobel RA, Zuniga L, Baranzini SE, Youssef S, Crowell A, Loh J, Oksenberg J, Steinman L. Peroxisome proliferator-activated receptor (PPAR) alpha expression in T cells mediates gender differences in development of T cell-mediated autoimmunity.
J. Exp. Med. 204: 321-330 (2007).
*
-
Dunne C, Shanahan F. Role of probiotics in the treatment of intestinal infections and inflammation.
Curr. Opin. Gastroenterol. 18: 40-45 (2002).
-
Dunnebier T, Bermejo JL, Haas S, Fischer HP, Pierl CB, Justenhoven C, Brauch H, Baisch C, Gilbert M, Harth V, Spickenheuer A, Rabstein S, Pesch B, Bruning T, Ko YD, Hamann U. Common variants in the UBC9 gene encoding the SUMO-conjugating enzyme are associated with breast tumor grade.
Int. J. Cancer 125: 596-602 (2009).
*
-
Dunnwald M, Zuberi AR, Stephens K, Le R, Sundberg JP, Fleckman P, Dale BA. The ichq mutant mouse, a model for the human skin disorder harlequin ichthyosis: mapping, keratinocyte culture, and consideration of candidate genes involved in epidermal growth regulation.
Exp. Dermatol. 12: 245-254 (2003).
*
-
Duntas LH. Selenium and inflammation: underlying anti-inflammatory mechanisms.
Horm. Metab. Res. 41: 443-447 (2009).
-
Duong FH, Christen V, Lin S, Heim MH. Hepatitis C virus-induced up-regulation of protein phosphatase 2A inhibits histone modification and DNA damage repair.
Hepatology Oct 22 [Epub ahead of print] (2009).
*
-
Dupe V, Matt N, Garnier JM, Chambon P, Mark M, Ghyselinck NB. A newborn lethal defect due to inactivation of retinaldehyde dehydrogenase type 3 is prevented by maternal retinoic acid treatment.
Proc. Natl. Acad. Sci. U.S.A. 100: 14036-14041 (2003).
*
-
Duplantier JG, Dubuisson L, Senant N, Freyburger G, Laurendeau I, Herbert JM, Desmouliere A, Rosenbaum J. A role for thrombin in liver fibrosis.
Gut 53: 1682-1687 (2004).
*
-
Duque-Guimaraes DE, de Castro J, Martinez-Botas J, Sardinha FL, Ramos MP, Herrera E, do Carmo MD. Early and prolonged intake of partially hydrogenated fat alters the expression of genes in rat adipose tissue.
Nutrition 25: 782-789 (2009).
*
-
Duran-Sandoval D, Cariou B, Percevault F, Hennuyer N, Grefhorst A, van Dijk TH, Gonzalez FJ, Fruchart JC, Kuipers F, Staels B. The farnesoid X receptor modulates hepatic carbohydrate metabolism during fasting/refeeding transition.
J. Biol. Chem. 280: 29971-29979 (2005).
*
-
Duran-Sandoval D, Mautino G, Martin G, Percevault F, Barbier O, Fruchart JC, Kuipers F, Staels B. Glucose regulates the expression of the farnesoid X receptor in liver.
Diabetes 53: 890-898 (2004).
*
-
Durant S, Pederzoli M, Lepelletier Y, Canteloup S, Nusbaum P, Lesavre P, Witko-Sarsat V. Apoptosis-induced proteinase 3 membrane expression is independent from degranulation.
J. Leukoc. Biol. 75: 87-98 (2004).
*
-
Durcan N, Costello RW, McLean WG, Blusztajn J, Madziar B, Fenech AG, Hall IP, Gleich GJ, McGarvey L, Walsh MT. Eosinophil-mediated cholinergic nerve remodeling.
Am. J. Respir. Cell. Mol. Biol. 34: 775-786 (2006).
*
-
Duret C, Daujat-Chavanieu M, Pascussi JM, Pichard-Garcia L, Balaguer P, Fabre JM, Vilarem MJ, Maurel P, Gerbal-Chaloin S. Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor.
Mol. Pharmacol. 70: 329-339 (2006).
*
-
Duret C, Gerbal-Chaloin S, Ramos J, Fabre JM, Jacquet E, Navarro F, Blanc P, Sa-Cunha A, Maurel P, Daujat-Chavanieu M. Isolation, characterization, and differentiation to hepatocyte-like cells of nonparenchymal epithelial cells from adult human liver.
Stem Cells 25: 1779-1790 (2007).
*
-
Durinovic-Bello I, Wu RP, Gersuk VH, Sanda S, Shilling HG, Nepom GT. Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin.
Genes Immun. Jan 7 [Epub ahead of print] (2010).
*
-
Durst KL, Hiebert SW. Role of RUNX family members in transcriptional repression and gene silencing.
Oncogene 23: 4220-4224 (2004).
*
-
Durston S, Fossella JA, Mulder MJ, Casey BJ, Ziermans TB, Vessaz MN, VAN Engeland H. Dopamine transporter genotype conveys familial risk of attention-deficit/hyperactivity disorder through striatal activation.
J. Am. Acad. Child. Adolesc. Psychiatry 47: 61-67 (2008).
-
Dussault I, Lin M, Hollister K, Wang EH, Synold TW, Forman BM. Peptide mimetic HIV protease inhibitors are ligands for the orphan receptor SXR.
J. Biol. Chem. 276: 33309-33312 (2001).
*
-
Dussault I, Yoo HD, Lin M, Wang E, Fan M, Batta AK, Salen G, Erickson SK, Forman BM. Identification of an endogenous ligand that activates pregnane X receptor-mediated sterol clearance.
Proc. Natl. Acad. Sci. U.S.A. 100: 833-838 (2003).
*
-
Dutra WO, Moreira PR, Souza PE, Gollob KJ, Gomez RS. Implications of cytokine gene polymorphisms on the orchestration of the immune response: lessons learned from oral diseases.
Cytokine Growth Factor Rev. 20: 223-232 (2009).
-
Dutzan N, Gamonal J, Silva A, Sanz M, Vernal R. Over-expression of forkhead box P3 and its association with receptor activator of nuclear factor-kappa B ligand, interleukin (IL) -17, IL-10 and transforming growth factor-beta during the progression of chronic periodontitis.
J. Clin. Periodontol. 36: 396-403 (2009).
-
Duvoix A, Delhalle S, Blasius R, Schnekenburger M, Morceau F, Fougere M, Henry E, Galteau MM, Dicato M, Diederich M. Effect of chemopreventive agents on glutathione S-transferase P1-1 gene expression mechanisms via activating protein 1 and nuclear factor kappaB inhibition.
Biochem. Pharmacol. 68: 1101-1011 (2004).
*
-
Duymaz-Tozkir J, Gul A, Uyar FA, Ozbek U, Saruhan-Direskeneli G. Tumour necrosis factor-alpha gene promoter region -308 and -376 G-->A polymorphisms in Behcet's disease.
Clin. Exp. Rheumatol. 21: S15-S18 (2003).
-
Duymaz-Tozkir J, Yilmaz V, Uyar FA, Hajeer AH, Saruhan-Direskeneli G, Gul A. Polymorphisms of the IL-8 and CXCR2 genes are not associated with Behcet's disease.
J. Rheumatol. 32: 93-97 (2005).
-
Dvorak Z, Modriansky M, Pichard-Garcia L, Balaguer P, Vilarem MJ, Ulrichova J, Maurel P, Pascussi JM. Colchicine down-regulates cytochrome P450 2B6, 2C8, 2C9, and 3A4 in human hepatocytes by affecting their glucocorticoid receptor-mediated regulation.
Mol. Pharmacol. 64: 160-169 (2003).
*
-
Dvorak Z, Vrzal R, Starha P, Klanicova A, Travnicek Z. Effects of dinuclear copper(II) complexes with 6-(benzylamino)purine derivatives on AhR and PXR dependent expression of cytochromes P450 CYP1A2 and CYP3A4 genes in primary cultures of human hepatocytes.
Toxicol. In Vitro Oct 22 [Epub ahead of print] (2009).
-
Dvorak Z, Vrzal R, Ulrichova J, Macejova D, Ondkova S, Brtko J. Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans-retinoic acid in primary rat hepatocytes.
Mol. Cell. Endocrinol. 267: 89-96 (2007).
-
Dvornyk V, Liu Y, Lu Y, Shen H, Lappe JM, Recker RR, Deng H, Lei S. Effect of menopause on gene expression profiles of circulating monocytes: a pilot in vivo microarray study.
J. Genet. Genomics 34: 974-983 (2007).
-
Dwyer KM, Deaglio S, Gao W, Friedman D, Strom TB, Robson SC. CD39 and control of cellular immune responses.
Purinergic Signal. 3: 171-180 (2007).
*
-
Dybkaer K, Iqbal J, Zhou G, Geng H, Xiao L, Schmitz A, D' Amore F, Chan WC. Genome wide transcriptional analysis of resting and IL2 activated human natural killer cells: gene expression signatures indicative of novel molecular signaling pathways.
BMC Genomics 8: 230 (2007).
*
-
Dziarski R. Peptidoglycan recognition proteins (PGRPs).
Mol. Immunol. 40: 877-886 (2004).
*
-
Dzidzuguri DV, Bakuradze ED, Kakhidze IG, Megrelishvili GZ, Kordzaia DD. Regeneration of white rat liver during cholestasis.
Tsitologiia 46: 411-415 (2004).
-
Dzik WH, Cserti-Gazdewich CM, Ssewanyana I, Delelys M, Preffer FI. When monocytes and platelets compete: the effect of platelet count on the flow cytometric measurement of monocyte CD36.
Cytometry B. Clin. Cytom. Nov 9 [Epub ahead of print] (2009).
-
Eastham LL, Mills CN, Niles RM. PPARalpha/gamma expression and activity in mouse and human melanocytes and melanoma cells.
Pharm. Res. 25: 1327-1333 (2008).
*
-
Eaves IA, Wicker LS, Ghandour G, Lyons PA, Peterson LB, Todd JA, Glynne RJ. Combining mouse congenic strains and microarray gene expression analyses to study a complex trait: the NOD model of type 1 diabetes.
Genome Res. 12: 232-243 (2002).
*
-
Eberhardt NL, Grebe SK, McIver B, Reddi HV. The role of the PAX8/PPARgamma fusion oncogene in the pathogenesis of follicular thyroid cancer.
Mol. Cell. Endocrinol. Oct 30 [Epub ahead of print] (2009).
-
Eberl G, Littman DR. The role of the nuclear hormone receptor RORgammat in the development of lymph nodes and Peyer's patches.
Immunol. Rev. 195: 81-90 (2003).
*
-
Ebert EC, Mehta V, Das KM. Activation antigens on colonic T cells in inflammatory bowel disease: effects of IL-10.
Clin. Exp. Immunol. 140: 157-165 (2005).
*
-
Ebert LM, Schaerli P, Moser B. Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues.
Mol. Immunol. 42: 799-809 (2005).
*
-
Ebert S, Weigelt K, Walczak Y, Drobnik W, Mauerer R, Hume DA, Weber BH, Langmann T. Docosahexaenoic acid attenuates microglial activation and delays early retinal degeneration.
J. Neurochem. 110: 1863-1875 (2009).
-
Ebihara N, Chen L, Tokura T, Ushio H, Iwatsu M, Murakami A. Distinct functions between Toll-like receptors 3 and 9 in retinal pigment epithelial cells.
Ophthalmic Res. 39: 155-163 (2007).
-
Ebihara T, Sakai N, Koyama S. CD8+ T cell subsets of cytotoxic T lymphocytes induced by Epstein-Barr virus infection in infectious mononucleosis.
Tohoku J. Exp. Med. 162: 213-224 (1990).
-
Ebinc FA, Derici U, Gonen S, Reis KA, Erten Y, Bali M, Sindel S, Arinsoy T. TGF-beta1 gene polymorphisms and peritoneal equilibration test results in CAPD patients.
Ren. Fail. 30: 15-19 (2008).
-
Ebling FJ, Barrett P. The regulation of seasonal changes in food intake and body weight.
J. Neuroendocrinol. 20: 827-833 (2008).
-
Ebrahimkhani MR, Kiani S, Oakley F, Kendall T, Shariftabrizi A, Tavangar SM, Moezi L, Payabvash S, Karoon A, Hoseininik H, Mann DA, Moore KP, Mani AR, Dehpour AR. Naltrexone, an opioid receptor antagonist, attenuates liver fibrosis in bile duct ligated rats.
Gut 55: 1606-1616 (2006).
*
-
Echchgadda I, Song CS, Oh T, Ahmed M, De La Cruz IJ, Chatterjee B. The xenobiotic-sensing nuclear receptors pregnane X receptor, constitutive androstane receptor, and orphan nuclear receptor hepatocyte nuclear factor 4alpha in the regulation of human steroid-/bile acid-sulfotransferase.
Mol. Endocrinol. 21: 2099-2111 (2007).
*
-
Echchgadda I, Song CS, Oh TS, Cho SH, Rivera OJ, Chatterjee B. Gene regulation for the senescence marker protein DHEA-sulfotransferase by the xenobiotic-activated nuclear pregnane X receptor (PXR).
Mech. Ageing Dev. 125: 733-745 (2004).
-
Ecker J, Liebisch G, Patsch W, Schmitz G. The conjugated linoleic acid isomer trans-9, trans-11 is a dietary occurring agonist of liver X receptor alpha.
Biochem. Biophys. Res. Commun. 388: 660-666 (2009).
*
-
Eckert GP, Vardanian L, Rebeck GW, Burns MP. Regulation of central nervous system cholesterol homeostasis by the liver X receptor agonist TO-901317.
Neurosci. Lett. 423: 47-52 (2007).
*
-
Eckey M, Hong W, Papaioannou M, Baniahmad A. The nucleosome assembly activity of NAP1 is enhanced by Alien.
Mol. Cell. Biol. 27: 3557-3568 (2007).
*
-
Eckmann L. Defence molecules in intestinal innate immunity against bacterial infections.
Curr. Opin. Gastroenterol. 21: 147-151 (2005).
-
Eckmann L. Innate immunity and mucosal bacterial interactions in the intestine.
Curr. Opin. Gastroenterol. 20: 82-88 (2004).
-
Eckstein AK, Johnson KT, Thanos M, Esser J, Ludgate M. Current insights into the pathogenesis of Graves' orbitopathy.
Horm. Metab. Res. 41: 456-464 (2009).
-
Edelman LB, Toia G, Geman D, Zhang W, Price ND. Two-transcript gene expression classifiers in the diagnosis and prognosis of human diseases.
BMC Genomics 10: 583 (2009).
*
-
Eder K, Gutgesell A, Ringseis R, Schmidt E, Brandsch C, Stangl G. Down-regulation of peroxisome proliferator-activated receptor alpha and its coactivators in liver and skeletal muscle mediates the metabolic adaptations during lactation in mice.
J. Mol. Endocrinol. 43: 241-250 (2009).
*
-
Eder T, Mayer R, Langsenlehner U, Renner W, Krippl P, Wascher TC, Pummer K, Kapp KS. Interleukin-10 [ATA] promoter haplotype and prostate cancer risk: a population-based study.
Eur. J. Cancer 43: 472-475 (2007).
*
-
Edgar AD, Tomkiewicz C, Costet P, Legendre C, Aggerbeck M, Bouguet J, Staels B, Guyomard C, Pineau T, Barouki R. Fenofibrate modifies transaminase gene expression via a peroxisome proliferator activated receptor alpha-dependent pathway.
Toxicol. Lett. 98: 13-23 (1998).
-
Edgel KA, Leboeuf RC, Oram JF. Tumor necrosis factor-alpha and lymphotoxin-alpha increase macrophage ABCA1 by gene expression and protein stabilization via different receptors.
Atherosclerosis Oct 22 [Epub ahead of print] (2009).
-
Edwards CJ, Feldman JL, Beech J, Shields KM, Stover JA, Trepicchio WL, Larsen G, Foxwell BM, Brennan FM, Feldmann M, Pittman DD. Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis.
Mol. Med. 13: 40-58 (2007).
*
-
Edwards G. Ivermectin: does P-glycoprotein play a role in neurotoxicity?
Filaria J. 2 Suppl. 1: S8 (2003).
*
-
Edwards IJ, O'Flaherty JT. Omega-3 fatty acids and PPARgamma in cancer.
PPAR Res. 2008: 358052 (2008).
*
-
Edwards IJ, Sun H, Hu Y, Berquin IM, O'Flaherty JT, Cline JM, Rudel LL, Chen YQ. In vivo and in vitro regulation of syndecan 1 in prostate cells by n-3 polyunsaturated fatty acids.
J. Biol. Chem. 283: 18441-18449 (2008).
*
-
Edwards PA, Kennedy MA, Mak PA. LXRs; oxysterol-activated nuclear receptors that regulate genes controlling lipid homeostasis.
Vascul. Pharmacol. 38: 249-256 (2002).
*
-
Edwards RA, Witherspoon M, Wang K, Afrasiabi K, Pham T, Birnbaumer L, Lipkin SM. Epigenetic repression of DNA mismatch repair by inflammation and hypoxia in inflammatory bowel disease-associated colorectal cancer.
Cancer Res. 69: 6423-6429 (2009).
*
-
Ee HL, Liu L, Goh CL, McGrath JA. Clinical and molecular dilemmas in the diagnosis of familial epidermolysis bullosa pruriginosa.
J. Am. Acad. Dermatol. 56: S77-S81 (2007).
-
Eerligh P, Koeleman BP, Dudbridge F, Jan Bruining G, Roep BO, Giphart MJ. Functional genetic polymorphisms in cytokines and metabolic genes as additional genetic markers for susceptibility to develop type 1 diabetes.
Genes Immun. 5: 36-40 (2004).
*
-
Eeva J, Nuutinen U, Ropponen A, Matto M, Eray M, Pellinen R, Wahlfors J, Pelkonen J. Feedback regulation of mitochondria by caspase-9 in the B cell receptor-mediated apoptosis.
Scand. J. Immunol. 70: 574-583 (2009).
*
-
Eferl R, Hasselblatt P, Rath M, Popper H, Zenz R, Komnenovic V, Idarraga MH, Kenner L, Wagner EF. Development of pulmonary fibrosis through a pathway involving the transcription factor Fra-2/AP-1.
Proc. Natl. Acad. Sci. U.S.A. 105: 10525-10530 (2008).
*
-
Efferth T. Adenosine triphosphate-binding cassette transporter genes in ageing and age-related diseases.
Ageing Res. Rev. 2: 11-24 (2003).
-
Efrati S, Berman S, Chachashvili A, Cohen N, Siman-Tov Y, Averbukh Z, Weissgarten J. Rosiglitazone treatment attenuates renal tissue inflammation generated by urinary tract obstruction.
Nephrology (Carlton) 14: 189-197 (2009).
-
Egan JB, Thompson PA, Vitanov MV, Bartik L, Jacobs ET, Haussler MR, Gerner EW, Jurutka PW. Vitamin D receptor ligands, adenomatous polyposis coli, and the vitamin D receptor FokI polymorphism collectively modulate beta-catenin activity in colon cancer cells.
Mol. Carcinog. Dec 30 [Epub ahead of print] (2009).
-
Egan LJ. Mechanism of action of established drugs: cyclosporine, methotrexate and others.
Falk Symposium 140. Inflammatory Bowel Disease: Translation from Basic Research to Clinical Practice. Dubrovnik (Croatia). p. 63-64. May 7-8 (2004). *
-
Egan ME, Pearson M, Weiner SA, Rajendran V, Rubin D, Glockner-Pagel J, Canny S, Du K, Lukacs GL, Caplan MJ. Curcumin, a major constituent of turmeric, corrects cystic fibrosis defects.
Science 304: 600-602 (2004).
*
-
Egawa S, Iijima H, Shinzaki S, Nakajima S, Wang J, Kondo J, Ishii S, Yoshio T, Irie T, Nishida T, Kakiuchi Y, Yasumaru M, Yoshihara H, Kanto T, Tsujii M, Tsuji S, Hayashi N. Upregulation of GRAIL is associated with remission of ulcerative colitis.
Am. J. Physiol. Gastrointest. Liver Physiol. 295: G163-G169 (2008).
*
-
Egawa T, Littman DR. ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage.
Nat. Immunol. 9: 1131-1139 (2008).
*
-
Egawa T, Tillman RE, Naoe Y, Taniuchi I, Littman DR. The role of the Runx transcription factors in thymocyte differentiation and in homeostasis of naive T cells.
J. Exp. Med. 204: 1945-1957 (2007).
*
-
Egefjord L, Jensen JL, Bang-Berthelsen CH, Petersen AB, Smidt K, Schmitz O, Karlsen AE, Pociot F, Chimienti F, Rungby J, Magnusson NE. Zinc transporter gene expression is regulated by pro-inflammatory cytokines: a potential role for zinc transporters in beta-cell apoptosis?
BMC Endocr. Disord. 9: 7 (2009).
*
-
Egesten A, Eliasson M, Olin AI, Erjefält JS, Bjartell A, Sangfelt P, Carlson M. The proinflammatory CXC-chemokines GRO-alpha/CXCL1 and MIG/CXCL9 are concomitantly expressed in ulcerative colitis and decrease during treatment with topical corticosteroids.
Int. J. Colorectal Dis. 22: 1421-1427 (2007).
*
-
Eggermont E. Gastrointestinal manifestations in cystic fibrosis.
Eur. J. Gastroenterol. Hepatol. 8: 731-738 (1996).
-
Egli RJ, Southam L, Wilkins JM, Lorenzen I, Pombo-Suarez M, Gonzalez A, Carr A, Chapman K, Loughlin J. Functional analysis of the osteoarthritis susceptibility-associated GDF5 regulatory polymorphism.
Arthritis Rheum. 60: 2055-2064 (2009).
*
-
Egusa H, Kaneda Y, Akashi Y, Hamada Y, Matsumoto T, Saeki M, Thakor DK, Tabata Y, Matsuura N, Yatani H. Enhanced bone regeneration via multimodal actions of synthetic peptide SVVYGLR on osteoprogenitors and osteoclasts.
Biomaterials 30: 4676-4686 (2009).
-
Ehlhardt S, Seifert M, Schneider J, Ojak A, Zang KD, Mehraein Y. Human endogenous retrovirus HERV-K(HML-2) Rec expression and transcriptional activities in normal and rheumatoid arthritis synovia.
J. Rheumatol. 33: 16-23 (2006).
-
Ehlin-Henriksson B, Liang W, Cagigi A, Mowafi F, Klein G, Nilsson A. Changes in chemokines and chemokine receptor expression on tonsillar B cells upon Epstein-Barr virus infection.
Immunology 127: 549-557 (2009).
*
-
Ehret MJ, Levin GM, Narasimhan M, Rathinavelu A. Venlafaxine induces P-glycoprotein in human Caco-2 cells.
Hum. Psychopharmacol. 22: 49-53 (2006).
-
Ehrhardt C, Collnot EM, Baldes C, Becker U, Laue M, Kim KJ, Lehr CM. Towards an in vitro model of cystic fibrosis small airway epithelium: characterisation of the human bronchial epithelial cell line CFBE41o-
Cell Tissue Res. 323: 405-415 (2006).
*
-
Eichelbaum M, Fromm MF, Schwab M. Clinical aspects of the MDR1 (ABCB1) gene polymorphism.
Ther. Drug Monit. 26: 180-185 (2004).
-
Eichenmuller M, Gruner I, Hagl B, Haberle B, Muller-Hocker J, von Schweinitz D, Kappler R. Blocking the hedgehog pathway inhibits hepatoblastoma growth.
Hepatology 49: 482-490 (2009).
*
-
Eichmuller SB, Bazhin AV. Onconeural versus paraneoplastic antigens?
Curr. Med. Chem. 14: 2489-2494 (2007).
-
Eidelman O, Srivastava M, Zhang J, Leighton X, Murtie J, Jozwik C, Jacobson K, Weinstein DL, Metcalf EL, Pollard HB. Control of the proinflammatory state in cystic fibrosis lung epithelial cells by genes from the TNF-alphaR/NFkappaB pathway.
Mol. Med. 7: 523-534 (2001).
*
-
Eidelman O, Zhang J, Srivastava M, Pollard HB. Cystic fibrosis and the use of pharmacogenomics to determine surrogate endpoints for drug discovery.
Am. J. Pharmacogenomics 1: 223-238 (2001).
-
Eilers M, Roy U, Mondal D. MRP (ABCC) transporters-mediated efflux of anti-HIV drugs, saquinavir and zidovudine, from human endothelial cells.
Exp. Biol. Med. (Maywood) 233: 1149-1160 (2008).
*
-
Einstein MH, Leanza S, Chiu LG, Schlecht NF, Goldberg GL, Steinberg BM, Burk RD. Genetic variants in TAP are associated with high-grade cervical neoplasia.
Clin. Cancer Res. 15: 1019-1023 (2009).
*
-
Einstein O, Grigoriadis N, Mizrachi-Kol R, Reinhartz E, Polyzoidou E, Lavon I, Milonas I, Karussis D, Abramsky O, Ben-Hur T. Transplanted neural precursor cells reduce brain inflammation to attenuate chronic experimental autoimmune encephalomyelitis.
Exp. Neurol. 198: 275-284 (2006).
*
-
Eipel C, Schuett H, Glawe C, Bordel R, Menger MD, Vollmar B. Pifithrin-alpha induced p53 inhibition does not affect liver regeneration after partial hepatectomy in mice.
J. Hepatol. 43: 829-835 (2005).
*
-
Eisfeld AJ, Yee MB, Erazo A, Abendroth A, Kinchington PR. Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase dependent and independent mechanisms.
J. Virol. 81: 9034-9049 (2007).
*
-
Eisinger AL, Nadauld LD, Shelton DN, Peterson PW, Phelps RA, Chidester S, Stafforini DM, Prescott SM, Jones DA. The adenomatous polyposis coli tumor suppressor gene regulates expression of cyclooxygenase-2 by a mechanism that involves retinoic acid.
J. Biol. Chem. 281: 20474-20482 (2006).
*
-
Eisinger AL, Nadauld LD, Shelton DN, Prescott SM, Stafforini DM, Jones DA. Retinoic acid inhibits beta-catenin through suppression of Cox-2: a role for truncated adenomatous polyposis coli.
J. Biol. Chem. 282: 29394-29400 (2007).
*
-
Eitsuka T, Nakagawa K, Suzuki T, Miyazawa T. Polyunsaturated fatty acids inhibit telomerase activity in DLD-1 human colorectal adenocarcinoma cells: a dual mechanism approach.
Biochim. Biophys. Acta 1737: 1-10 (2005).
*
-
Ejiri N, Katayama KI, Kiyosawa N, Baba Y, Doi K. Microarray analysis on phase II drug metabolizing enzymes expression in pregnant rats after treatment with pregnenolone-16alpha-carbonitrile or phenobarbital.
Exp. Mol. Pathol. 79: 272-277 (2005).
*
-
Ekici M, Hohl M, Schuit F, Martinez-Serrano A, Thiel G. Transcription of genes encoding synaptic vesicle proteins in human neural stem cells: chromatin accessibility, histone methylation pattern and essential role of REST.
J. Biol. Chem. 283: 9257-9268 (2008).
*
-
Ekins S, Andreyev S, Rybadov A, Kirillov E, Rakhmatulin EA, Sorokina S, Bugrim A, Nikolskaya T. A combined approach to drug metabolism and toxicity assessment.
Drug Metab. Dispos. 34: 495-503 (2006).
*
-
Ekins S, Kirillov E, Rakhmatulin EA, Nikolskaya T. A novel method for visualizing nuclear hormone receptor networks relevant to drug metabolism.
Drug Metab. Dispos. 33: 474-481 (2005).
*
-
Eklow C, Makrygiannakis D, Backdahl L, Padyukov L, Ulfgren AK, Lorentzen JC, Malmstrom V. Cellular distribution of the C-type II lectin dendritic cell immunoreceptor (DCIR) and its expression in the rheumatic joint: identification of a subpopulation of DCIR+ T cells.
Ann. Rheum. Dis. 67: 1742-1749 (2008).
-
El Boustany C, Bidaux G, Enfissi A, Delcourt P, Prevarskaya N, Capiod T. Capacitative calcium entry and transient receptor potential canonical 6 expression control human hepatoma cell proliferation.
Hepatology 47: 2068-2077 (2008).
*
-
El Eter E, Al Tuwaijiri A, Hagar H, Arafa M. In vivo and in vitro antioxidant activity of ghrelin: attenuation of gastric ischemic injury in the rat.
J. Gastroenterol. Hepatol. 22: 1791-1799 (2007).
*
-
El Kasmi KC, Smith AM, Williams L, Neale G, Panopolous AD, Watowich SS, Hacker H, Foxwell BM, Murray PJ. Cutting edge: a transcriptional repressor and corepressor induced by the STAT3-regulated anti-inflammatory signaling pathway.
J. Immunol. 179: 7215-7219 (2007).
*
-
El Kebir D, Jozsef L, Pan W, Wang L, Filep JG. Bacterial DNA activates endothelial cells and promotes neutrophil adherence through TLR9 signaling.
J. Immunol. 182: 4386-4394 (2009).
-
El Kebir D, Jozsef L, Pan W, Wang L, Petasis NA, Serhan CN, Filep JG. 15-epi-Lipoxin A4 inhibits myeloperoxidase signaling and enhances resolution of acute lung injury.
Am. J. Respir. Crit. Care Med. 180: 311-319 (2009).
*
-
El Mabrouk M, Qureshi HY, Li WQ, Sylvester J, Zafarullah M. Interleukin-4 antagonizes oncostatin M and transforming growth factor beta-induced responses in articular chondrocytes.
J. Cell. Biochem. 103: 588-597 (2008).
*
-
El Mezayen R, El Gazzar M, Myer R, High KP. Aging-dependent upregulation of IL-23p19 gene expression in dendritic cells is associated with differential transcription factor binding and histone modifications.
Aging Cell 8: 553-565 (2009).
*
-
El Mokhtari NE, Ott SJ, Nebel A, Schaefer A, Rosenstiel P, Foerster M, Nothnagel M, Simon R, Schreiber S. Role of NOD2/CARD15 in coronary heart disease.
BMC Genet. 8: 76 (2007).
*
-
El-Bayoumy K, Sinha R. Molecular chemoprevention by selenium: a genomic approach.
Mutat. Res. 591: 224-236 (2005).
-
El-Domyati M, Barakat M, Abdel-Razek R, El-Din Anbar T. Apoptosis, P53 and Bcl-2 expression in response to topical calcipotriol therapy for psoriasis.
Int. J. Dermatol. 46: 468-474 (2007).
*
-
El-Magadmi M, Alansari A, Teh LS, Ordi J, Gul A, Inanc M, Bruce I, Hajeer A. Association of the A561C E-selectin polymorphism with systemic lupus erythematosus in 2 independent populations.
J. Rheumatol. 28: 2650-2652 (2001).
-
El-Nour H, Santos A, Nordin M, Jonsson P, Svensson M, Nordlind K, Berg M. Neuronal changes in psoriasis exacerbation.
J. Eur. Acad. Dermatol. Venereol. 23: 1240-1245 (2009).
*
-
El-Obeid A, Hassib A, Ponten F, Westermark B. Effect of herbal melanin on IL-8: a possible role of Toll-like receptor 4 (TLR4).
Biochem. Biophys. Res. Commun. 344: 1200-1206 (2006).
*
-
El-Sankary W, Bombail V, Gibson GG, Plant N. Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element.
Drug Metab. Dispos. 30: 1029-1034 (2002).
*
-
El-Sohemy A. Nutrigenetics.
Forum Nutr. 60: 25-30 (2007).
-
El-Swefy S, Hassanen SI. Improvement of hepatic fibrosis by leukotriene inhibition in cholestatic rats.
Ann. Hepatol. 8: 41-49 (2009).
*
-
El-Tanani M, Platt-Higgins A, Rudland PS, Campbell FC. Ets gene PEA3 cooperates with beta-catenin-Lef-1 and c-Jun in regulation of osteopontin transcription.
J. Biol. Chem. 279: 20794-20806 (2004).
*
-
El-Tanani MK, Campbell FC, Crowe P, Erwin P, Harkin DP, Pharoah P, Ponder B, Rudland PS. BRCA1 suppresses osteopontin-mediated breast cancer.
J. Biol. Chem. 281: 26587-2601 (2006).
*
-
Elam MB, Cowan GS Jr, Rooney RJ, Hiler ML, Yellaturu CR, Deng X, Howell GE, Park EA, Gerling IC, Patel D, Corton JC, Cagen LM, Wilcox HG, Gandhi M, Bahr MH, Allan MC, Wodi LA, Cook GA, Hughes TA, Raghow R. Hepatic gene expression in morbidly obese women: implications for disease susceptibility.
Obesity (Silver Spring) 17: 1563-1573 (2009).
*
-
Elamanchili P, Lutsiak CM, Hamdy S, Diwan M, Samuel J. "Pathogen-mimicking" nanoparticles for vaccine delivery to dendritic cells.
J. Immunother. 30: 378-395 (2007).
-
Elander N, Zhou J, Ungerback J, Dimberg J, Soderkvist P. Association between adenomatosis polyposis coli functional status and microsomal prostaglandin E synthase-1 expression in colorectal cancer.
Mol. Carcinog. 48: 401-407 (2009).
*
-
Elbarbary RA, Takaku H, Tamura M, Nashimoto M. Inhibition of vascular endothelial growth factor expression by TRUE gene silencing.
Biochem. Biophys. Res. Commun. 379: 924-927 (2009).
*
-
Elbein SC, Chu WS, Das SK, Yao-Borengasser A, Hasstedt SJ, Wang H, Rasouli N, Kern PA. Transcription factor 7-like 2 polymorphisms and type 2 diabetes, glucose homeostasis traits and gene expression in US participants of European and African descent.
Diabetologia 50: 1621-1630 (2007).
*
-
Elbekai RH, Korashy HM, El-Kadi AOS. The effect of liver cirrhosis on the regulation and expression of drug metabolizing enzymes.
Curr. Drug Metab. 5: 157-167 (2004).
-
Elco CP, Sen GC. Stat1 required for interferon-inducible but not constitutive responsiveness to extracellular dsRNA.
J. Interferon Cytokine Res. 27: 411-424 (2007).
-
Elder DJ, Halton DE, Hague A, Paraskeva C. Induction of apoptotic cell death in human colorectal carcinoma cell lines by a cyclooxygenase-2 (COX-2)-selective nonsteroidal anti-inflammatory drug: independence from COX-2 protein expression.
Clin. Cancer Res. 3: 1679-1683 (1997).
*
-
Elder JT. IL-15 and psoriasis: another genetic link to Th17?
J. Invest. Dermatol. 127: 2495-2497 (2007).
*
-
Elder LT, Klein SB, Tavakkol A, Fisher GJ, Nickoloff BJ, Voorhees JJ. Growth factor and proto-oncogene expression in psoriasis.
J. Invest. Dermatol. 95: 7S-9S (1990).
*
-
Elefteriou F, Benson MD, Sowa H, Starbuck M, Liu X, Ron D, Parada LF, Karsenty G. ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae.
Cell. Metab. 4: 441-451 (2006).
*
-
Eleftheriadis T, Kartsios C, Yiannaki E, Kazila P, Antoniadi G, Liakopoulos V, Markala D. Chronic inflammation and T cell zeta-chain downregulation in hemodialysis patients.
Am. J. Nephrol. 28: 152-157 (2008).
-
Eletto D, Leone A, Bifulco M, Tecce MF. Effect of unsaturated fat intake from Mediterranean diet on rat liver mRNA expression profile: selective modulation of genes involved in lipid metabolism.
Nutr. Metab. Cardiovasc. Dis. 15: 13-23 (2005).
-
Eley L, Gabrielides C, Adams M, Johnson CA, Hildebrandt F, Sayer JA. Jouberin localizes to collecting ducts and interacts with nephrocystin-1.
Kidney Int. 74: 1139-1149 (2008).
*
-
Elghazi L, Weiss AJ, Barker DJ, Callaghan J, Staloch L, Sandgren EP, Gannon M, Adsay VN, Bernal-Mizrachi E. Regulation of pancreas plasticity and malignant transformation by Akt signaling.
Gastroenterology 136: 1091-1103.e8 (2009).
*
-
Elgueta R, Sepulveda FE, Vilches F, Vargas L, Mora JR, Bono MR, Rosemblatt M. Imprinting of CCR9 on CD4 T cells requires IL-4 signaling on mesenteric lymph node dendritic cells.
J. Immunol. 180: 6501-6507 (2008).
*
-
Elias E, Mills CO. Coordinated defence and the liver.
Clin. Med. 7: 180-184 (2007).
-
Elias PM, Arbiser J, Brown BE, Rossiter H, Man MQ, Cerimele F, Crumrine D, Gunathilake R, Choi EH, Uchida Y, Tschachler E, Feingold KR. Epidermal vascular endothelial growth factor production is required for permeability barrier homeostasis, dermal angiogenesis, and the development of epidermal hyperplasia. Implications for the pathogenesis of psoriasis.
Am. J. Pathol. 173: 689-699 (2008).
*
-
Elinav E, Ali M, Bruck R, Brazowski E, Phillips A, Shapira Y, Katz M, Solomon G, Halpern Z, Gertler A. Competitive inhibition of leptin signaling results in amelioration of liver fibrosis through modulation of stellate cell function.
Hepatology 49: 278-286 (2009).
*
-
Elinson RP, Walton Z, Nath K. Raldh expression in embryos of the direct developing frog Eleutherodactylus coqui and the conserved retinoic acid requirement for forelimb initiation.
J. Exp. Zoolog. B. Mol. Dev. Evol. 310B: 588-595 (2008).
-
Eliopoulos AG, Caamano JH, Flavell J, Reynolds GM, Murray PG, Poyet JL, Young LS. Epstein-Barr virus-encoded latent infection membrane protein 1 regulates the processing of p100 NF-kappaB2 to p52 via an IKKgamma/NEMO-independent signalling pathway.
Oncogene 22: 7557-7569 (2003).
*
-
Elizondo G, Medina-Diaz IM, Cruz R, Gonzalez FJ, Vega L. Retinoic acid modulates retinaldehyde dehydrogenase 1 gene expression through the induction of GADD153-C/EBPbeta interaction.
Biochem. Pharmacol. 77: 248-257 (2009).
*
-
Ellegren H, Parsch J. The evolution of sex-biased genes and sex-biased gene expression.
Nat. Rev. Genet. 8: 689-698 (2007).
*
-
Eller E, Vardi P, McFann KK, Babu SR, Yu L, Bugawan TL, Erlich HA, Eisenbarth GS, Fain PR. Differential effects of DRB1(*)0301 and DQA1(*)0501-DQB1(*)0201 on the activation and progression of islet cell autoimmunity.
Genes Immun. 8: 628-633 (2007).
*
-
Ellerman JE, Brown CK, de Vera M, Zeh HJ, Billiar T, Rubartelli A, Lotze MT. Masquerader: high mobility group box-1 and cancer.
Clin. Cancer Res. 13: 2836-2848 (2007).
*
-
Elliott DE, Summers RW, Weinstock JV. Helminths and the modulation of mucosal inflammation.
Curr. Opin. Gastroenterol. 21: 51-58 (2005).
-
Elliott J. SOCS3 in liver regeneration and hepatocarcinoma.
Mol. Interv. 8: 19-21 (2008).
*
-
Ellis JA, Stebbing M, Harrap SB. Polymorphism of the androgen receptor gene is associated with male pattern baldness.
J. Invest. Dermatol. 116: 452-455 (2001).
*
-
Ellmark P, Woolfson A, Belov L, Christopherson RI. The applicability of a cluster of differentiation monoclonal antibody microarray to the diagnosis of human disease.
Methods Mol. Biol. 439: 199-209 (2008).
*
-
Elloumi HZ, Holland SM. Complex regulation of human cathelicidin gene expression: novel splice variants and 5'UTR negative regulatory element.
Mol. Immunol. 45: 204-217 (2008).
*
-
Elner SG, Petty HR, Elner VM, Yoshida A, Bian ZM, Yang D, Kindezelskii AL. TLR4 mediates human retinal pigment epithelial endotoxin binding and cytokine expression.
Trans. Am. Ophthalmol. Soc. 103: 126-137 (2005).
*
-
Elomaa O, Majuri I, Suomela S, Asumalahti K, Jiao H, Mirzaei Z, Rozell B, Dahlman-Wright K, Pispa J, Kere J, Saarialho-Kere U. Transgenic mouse models support HCR as an effector gene in the PSORS1 locus.
Hum. Mol. Genet. 13: 1551-1561 (2004).
*
-
Eloranta JJ, Hiller C, Hausler S, Stieger B, Kullak-Ublick GA. Vitamin D3 and its nuclear receptor increase the expression and activity of the human proton-coupled folate transporter.
Mol. Pharmacol. 76: 1062-1071 (2009).
-
Elrefaei M, Burke CM, Baker CA, Jones NG, Bousheri S, Bangsberg DR, Cao H. TGF-beta and IL-10 production by HIV-specific CD8+ T cells is regulated by CTLA-4 signaling on CD4+ T cells.
PLoS One 4: e8194 (2009).
*
-
Elson CO, Cong Y, Sundberg J. The C3H/HeJBir mouse model: a high susceptibility phenotype for colitis.
Int. Rev. Immunol. 19: 63-75 (2000).
-
Emamian ES, Leon JM, Lessard CJ, Grandits M, Baechler EC, Gaffney PM, Segal B, Rhodus NL, Moser KL. Peripheral blood gene expression profiling in Sjogren's syndrome.
Genes Immun. 10: 285-296 (2009).
*
-
Embree-Ku M, Gruppuso PA. The role of nuclear factor kappaB in late-gestation liver development in the rat.
Hepatology 42: 326-334 (2005).
*
-
Emery B, Butzkueven H, Snell C, Binder M, Kilpatrick TJ. Oligodendrocytes exhibit selective expression of suppressor of cytokine signaling genes and signal transducer and activator of transcription 1 independent inhibition of interferon-gamma-induced toxicity in response to leukemia inhibitory factor.
Neuroscience 137: 463-472 (2006).
-
Emilsson V, Thorleifsson G, Zhang B, Leonardson AS, Zink F, Zhu J, Carlson S, Helgason A, Walters GB, Gunnarsdottir S, Mouy M, Steinthorsdottir V, Eiriksdottir GH, Bjornsdottir G, Reynisdottir I, Gudbjartsson D, Helgadottir A, Jonasdottir A, et al. Genetics of gene expression and its effect on disease.
Nature 452: 423-428 (2008).
*
-
Eminli S, Foudi A, Stadtfeld M, Maherali N, Ahfeldt T, Mostoslavsky G, Hock H, Hochedlinger K. Differentiation stage determines potential of hematopoietic cells for reprogramming into induced pluripotent stem cells.
Nat. Genet. 41: 968-976 (2009).
*
-
Emmer A, Gerlach K, Staege MS, Kornhuber ME. Cerebral gene expression of superantigen encephalitis in the Lewis rat induced by staphylococcal enterotoxin A.
Scand. J. Immunol. 67: 464-472 (2008).
*
-
Endo I, Inoue D, Mitsui T, Umaki Y, Akaike M, Yoshizawa T, Kato S, Matsumoto T. Deletion of vitamin D receptor gene in mice results in abnormal skeletal muscle development with deregulated expression of myoregulatory transcription factors.
Endocrinology 144: 5138-5144 (2003).
*
-
Endo K, Kinouchi Y, Kakuta Y, Ueki N, Takahashi S, Shimosegawa T. Involvement of NF-kappa B pathway in TL1A gene expression induced by lipopolysaccharide.
Cytokine Oct 6 [Epub ahead of print] (2009).
-
Endo K, Yoon BI, Pairojkul C, Demetris AJ, Sirica AE. ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions.
Hepatology 36: 439-450 (2002).
*
-
Endo M, Antonyak MA, Cerione RA. CDC42-mTOR signaling pathway controls HES5 and PAX6 expression in retinoic acid-dependent neural differentiation.
J. Biol. Chem. 284: 5107-5118 (2009).
*
-
Endo Y, Marusawa H, Kinoshita K, Morisawa T, Sakurai T, Okazaki IM, Watashi K, Shimotohno K, Honjo T, Chiba T. Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling.
Oncogene 26: 5587-5595 (2007).
*
-
Endo Y, Marusawa H, Kou T, Nakase H, Fujii S, Fujimori T, Kinoshita K, Honjo T, Chiba T. Activation-induced cytidine deaminase: links between inflammation and the development of colitis-associated colorectal cancers.
Gastroenterology 135: 889-898.e3 (2008).
*
-
Endresen MJ. The role of fatty acids in gene regulation. An example of an important nutritional factor which may influence our genes.
Tidsskr. Nor. Laegeforen. 115: 2084-2086 (1995).
-
Enerback C, Enlund F, Inerot A, Samuelsson L, Wahlstrom J, Swanbeck G, Martinsson T. S gene (Corneodesmosin) diversity and its relationship to psoriasis; high content of cSNP in the HLA-linked S gene.
J. Invest. Dermatol. 114: 1158-1163 (2000).
*
-
Enesa K, Zakkar M, Chaudhury H, Luong LA, Rawlinson L, Mason JC, Haskard DO, Dean JL, Evans PC. NF-kappaB suppression by the deubiquitinating enzyme cezanne: a novel negative feedback loop in pro-inflammatory signaling.
J. Biol. Chem. 283: 7036-7045 (2008).
*
-
Eng FJ, Friedman SL. Transcriptional regulation in hepatic stellate cells.
Semin. Liver Dis. 21: 385-395 (2001).
-
Eng HL, Wang CH, Chen CH, Chou MH, Cheng CT, Lin TM. A CD14 promoter polymorphism is associated with CD14 expression and Chlamydia-stimulated TNF alpha production.
Genes Immun. 5: 426-430 (2004).
*
-
Engdahl R, Monroy MA, Daly JM. 15-Deoxy-Delta(12,14)-prostaglandin J2 (15d-PGJ2) mediates repression of TNF-alpha by decreasing levels of acetylated histone H3 and H4 at its promoter.
Biochem. Biophys. Res. Commun. 359: 88-93 (2007).
*
-
Engel I, Murre C. The function of E- and Id proteins in lymphocyte development.
Nat. Rev. Immunol. 1: 193-199 (2001).
*
-
Engel T, Kannenberg F, Fobker M, Nofer JR, Bode G, Lueken A, Assmann G, Seedorf U. Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.
FEBS Lett. 581: 1673-1680 (2007).
*
-
Engel T, Lorkowski S, Lueken A, Rust S, Schluter B, Berger G, Cullen P, Assmann G. The human ABCG4 gene is regulated by oxysterols and retinoids in monocyte-derived macrophages.
Biochem. Biophys. Res. Commun. 288: 483-488 (2001).
*
-
Engelhard A, Bauer RC, Casta A, Djabali K, Christiano AM. Ligand-independent regulation of the hairless promoter by vitamin D receptor.
Photochem. Photobiol. 84: 515-521 (2008).
-
Engelhardt B. Molecular mechanisms involved in T cell migration across the blood-brain barrier.
J. Neural. Transm. 113: 477-485 (2006).
*
-
Enjoji M, Yada R, Fujino T, Yoshimoto T, Yada M, Harada N, Higuchi N, Kato M, Kohjima M, Taketomi A, Maehara Y, Nakashima M, Kotoh K, Nakamuta M. The state of cholesterol metabolism in the liver of patients with primary biliary cirrhosis: the role of MDR3 expression.
Hepatol. Int. Jun 16 [Epub ahead of print] (2009).
*
-
Enke U, Seyfarth L, Schleussner E, Markert UR. Impact of PUFA on early immune and fetal development.
Br. J. Nutr. 100: 1158-1168 (2008).
*
-
Enlow RW, Bias WB, Arnett FC. The spondylitis of inflammatory bowel disease. Evidence for a non-HLA linked axial arthropathy.
Arthritis Rheum. 23: 1359-1365 (1980).
-
Enomoto H, Nakamura H, Liu W, Yoshida K, Okuda Y, Imanishi H, Saito M, Shimomura S, Hada T, Nishiguchi S. Hepatoma-derived growth factor is induced in liver regeneration.
Hepatol. Res. 39: 988-997 (2009).
*
-
Enstrom AM, Lit L, Onore CE, Gregg JP, Hansen R, Pessah IN, Hertz-Picciotto I, Van de Water JA, Sharp FR, Ashwood P. Altered gene expression and function of peripheral blood natural killer cells in children with autism.
Brain Behav. Immun. 23: 124-133 (2009).
-
Enzler T, Chang X, Facchinetti V, Melino G, Karin M, Su B, Gallagher E. MEKK1 binds HECT E3 ligase Itch by its amino-terminal RING motif to regulate Th2 cytokine gene expression.
J. Immunol. 183: 3831-3838 (2009).
-
Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE. The mouse genome database (MGD): new features facilitating a model system.
Nucleic Acids Res. 35: D630-D637 (2007).
*
-
Epping MT, Meijer LA, Bos JL, Bernards R. UNC45A confers resistance to histone deacetylase inhibitors and retinoic acid.
Mol. Cancer Res. 7: 1861-1870 (2009).
*
-
Epping MT, Wang L, Plumb JA, Lieb M, Gronemeyer H, Brown R, Bernards R. A functional genetic screen identifies retinoic acid signaling as a target of histone deacetylase inhibitors.
Proc. Natl. Acad. Sci. U.S.A. 104: 17777-17782 (2007).
*
-
Epple R, Cow C, Xie Y, Azimioara M, Russo R, Wang X, Wityak J, Karanewsky DS, Tuntland T, Nguyen-Tran VT, Cuc Ngo C, Huang D, Saez E, Spalding T, Gerken A, Iskandar M, Seidel HM, Tian SS. Novel bisaryl substituted thiazoles and oxazoles as highly potent and selective peroxisome proliferator-activated receptor delta agonists.
J. Med. Chem. Nov 20 [Epub ahead of print] (2009).
*
-
Epstein DJ. Cis-regulatory mutations in human disease.
Brief. Funct. Genomic. Proteomic. 8: 310-316 (2009).
-
Eran E, Nitzan A, Tova W, Eshhar Z. Amelioration of colitis by genetically engineered murine regulatory T cells redir
| |