gene expression, Primary Sclerosing Cholangitis Literature

Primary Sclerosing Cholangitis Literature

Home Page

FAQ

PSC Partners

www Resources

Scientific Literature

Scientific Literature, gene expression

Aaltonen J, Bjorses P. Cloning of the APECED gene provides new insight into human autoimmunity. Ann. Med. 31: 111-116 (1999).
Abal M, Obrador-Hevia A, Janssen KP, Casadome L, Menendez M, Carpentier S, Barillot E, Wagner M, Ansorge W, Moeslein G, Fsihi H, Bezrookove V, Reventos J, Louvard D, Capella G, Robine S. APC inactivation associates with abnormal mitosis completion and concomitant BUB1B/MAD2L1 up-regulation. Gastroenterology 132: 2448-2458 (2007). *
Abate N, Chandalia M, Di Paola R, Foster DW, Grundy SM, Trischitta V. Mechanisms of disease: ectonucleotide pyrophosphatase phosphodiesterase 1 as a 'gatekeeper' of insulin receptors. Nat. Clin. Pract. Endocrinol. Metab. 2: 694-701 (2006). *
Abba MC, Hu Y, Levy CC, Gaddis S, Kittrell FS, Zhang Y, Hill J, Bissonnette RP, Medina D, Brown PH, Aldaz CM. Transcriptomic signature of the chemopreventive bexarotene (rexinoid LGD1069) on mammary gland from three transgenic mouse mammary cancer models. BMC Med. Genomics 1: 40 (2008). *
Abbas AR, Baldwin D, Ma Y, Ouyang W, Gurney A, Martin F, Fong S, van Lookeren Campagne M, Godowski P, Williams PM, Chan AC, Clark HF. Immune response in silico (IRIS): immune-specific genes identified from a compendium of microarray expression data. Genes Immun. 6: 319-331 (2005). *
Abbasi AM, Chester KA, MacPherson AJ, Boxer GM, Begent RH, Malcolm AD. Localization of CEA messenger RNA by in situ hybridization in normal colonic mucosa and colorectal adenocarcinomas. J. Pathol. 168: 405-411 (1992).
Abbey JL, O'Neill HC. Expression of T-cell receptor genes during early T-cell development. Immunol. Cell Biol. 86: 166-174 (2008). *
Abbott BD. Review of the expression of peroxisome proliferators activated receptors alpha (PPARalpha), beta (PPARbeta), and gamma (PPARgamma) in rodent and human development. Reprod. Toxicol. 27: 246-257 (2009).
Abbott BD, Wolf CJ, Schmid JE, Das KP, Zehr RD, Helfant L, Nakayama S, Lindstrom AB, Strynar MJ, Lau CS. Perfluorooctanoic acid (PFOA)-induced developmental toxicity in the mouse is dependent on expression of peroxisome proliferator activated receptor-alpha (PPARalpha). Toxicol. Sci. 98: 571-581 (2007). *
Abd El-Ghaffar HA, Aladle DA, Farahat SE, Abd El-Hady N. P-Glycoprotein (P-170) expression in acute leukemias. Hematology 11: 35-41 (2006).
Abdelmalek MF, Liu C, Shuster J, Nelson DR, Asal NR. Familial aggregation of insulin resistance in first-degree relatives of patients with nonalcoholic fatty liver disease. Clin. Gastroenterol. Hepatol. 4: 1162-1169 (2006).
Abdeltawab NF, Aziz RK, Kansal R, Rowe SL, Su Y, Gardner L, Brannen C, Nooh MM, Attia RR, Abdelsamed HA, Taylor WL, Lu L, Williams RW, Kotb M. An unbiased systems genetics approach to mapping genetic loci modulating susceptibility to severe streptococcal sepsis. PLoS Pathog. 4: e1000042 (2008). *
Abdgawad M, Hellmark T, Gunnarsson L, Westman KW, Segelmark M. Increased neutrophil membrane expression and plasma level of proteinase 3 in systemic vasculitis are not a consequence of the - 564 A/G promotor polymorphism. Clin. Exp. Immunol. 145: 63-70 (2006). *
Abdollahi-Roodsaz S, Joosten LA, Roelofs MF, Radstake TR, Matera G, Popa C, van der Meer JW, Netea MG, van den Berg WB. Inhibition of Toll-like receptor 4 breaks the inflammatory loop in autoimmune destructive arthritis. Arthritis Rheum. 56: 2957-2967 (2007). *
Abdou AG, Hanout HM. Evaluation of survivin and NF-kappaB in psoriasis, an immunohistochemical study. J. Cutan. Pathol. 35: 445-451 (2008).
Abdulahad WH, van der Geld YM, Stegeman CA, Kallenberg CG. Persistent expansion of CD4(+) effector memory T cells in Wegener's granulomatosis. Kidney Int. 70: 938-947 (2006). *
Abdulrahman W, Uhring M, Kolb-Cheynel I, Garnier JM, Moras D, Rochel N, Busso D, Poterszman A. A set of baculovirus transfer vectors for screening of affinity tags and parallel expression strategies. Anal. Biochem. 385: 383-385 (2009). *
Abe K, Klaften M, Narita A, Kimura T, Imai K, Kimura M, Rubio-Aliaga I, Wagner S, Jakob T, Hrabe de Angelis M. Genome-wide search for genes that modulate inflammatory arthritis caused by Ali18 mutation in mice. Mamm. Genome 20: 152-161 (2009).
Abe S, Hanawa H, Hayashi M, Yoshida T, Komura S, Watanabe R, Lie H, Chang H, Kato K, Kodama M, Maruyama H, Nakazawa M, Miyazaki J, Aizawa Y. Prevention of experimental autoimmune myocarditis by hydrodynamics-based naked plasmid DNA encoding CTLA4-Ig gene delivery. J. Card. Fail. 11: 557-564 (2005).
Abebe F, Mustafa T, Nerland AH, Bjune GA. Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease. Clin. Exp. Immunol. 143: 180-192 (2006). *
Abedin SA, Banwell CM, Colston KW, Carlberg C, Campbell MJ. Epigenetic corruption of VDR signalling in malignancy. Anticancer Res. 26: 2557-2566 (2006).
Abedin SA, Thorne JL, Battaglia S, Maguire O, Hornung L, Doherty AP, Mills IG, Campbell MJ. Elevated NCOR1 disrupts a network of dietary-sensing nuclear receptors in bladder cancer cells. Carcinogenesis 30: 449-456 (2009). *
Abel S, Hundhausen C, Mentlein R, Schulte A, Berkhout TA, Broadway N, Hartmann D, Sedlacek R, Dietrich S, Muetze B, Schuster B, Kallen KJ, Saftig P, Rose-John S, Ludwig A. The transmembrane CXC-chemokine ligand 16 is induced by IFN-gamma and TNF-alpha and shed by the activity of the disintegrin-like metalloproteinase ADAM10. J. Immunol. 172: 6362-6372 (2004). *
Abel S, Yang Y, Waring JF. Development of an in vitro gene expression assay for predicting hepatotoxicity. ALTEX 23: S326-S331 (2006).
Abelson AK, Delgado-Vega AM, Kozyrev SV, Sanchez E, Velazquez-Cruz R, Eriksson N, Wojcik J, Linga Reddy P, Lima G, D'Alfonso S, Migliaresi S, Baca V, Orozco L, Witte T, Ortego-Centeno N, Abderrahim H, Pons-Estel BA, Gutierrez C, Suarez A, et al. STAT4 associates with SLE through two independent effects that correlate with gene expression and act additively with IRF5 to increase risk. Ann. Rheum. Dis. Dec 9 [Epub ahead of print] (2008).
Aberle J, Flitsch J, Beck NA, Mann O, Busch P, Peitsmeier P, Beil FU. Genetic variation may influence obesity only under conditions of diet: analysis of three candidate genes. Mol. Genet. Metab. 95: 188-191 (2008). *
Abeywardena MY, Head RJ. Longchain n-3 polyunsaturated fatty acids and blood vessel function. Cardiovasc. Res. 52: 361-371 (2001). *
Abildayeva K, Jansen PJ, Hirsch-Reinshagen V, Bloks VW, Bakker AH, Ramaekers FC, De Vente J, Groen AK, Wellington CL, Kuipers F, Mulder M. 24(S)-Hydroxycholesterol participates in a liver X receptor-controlled pathway in astrocytes that regulates apolipoprotein E-mediated cholesterol efflux. J. Biol. Chem. 281: 12799-12808 (2006). *
Abiru N, Kawasaki E, Eguch K. Current knowledge of Japanese type 1 diabetic syndrome. Diabetes Metab. Res. Rev. 18: 357-366 (2002). *
Abo T, Ohteki T, Seki S, Koyamada N, Yoshikai Y, Masuda T, Rikiishi H, Kumagai K. The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. J. Exp. Med. 174: 417-424 (1991). *
Aboul-Enein F, Weiser P, Hoftberger R, Lassmann H, Bradl M. Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis. Acta Neuropathol. (Berl.) 111: 539-547 (2006).
Abraham C, Cho J. Interleukin-23/Th17 pathways and inflammatory bowel disease. Inflamm. Bowel Dis. 15: 1090-1100 (2009). *
Abraham DJ, Varga J. Scleroderma: from cell and molecular mechanisms to disease models. Trends Immunol. 26: 587-595 (2005). *
Abraham LJ, Kroeger KM. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J. Leukoc. Biol. 66: 562-566 (1999). *
Abrantes EF, Pires EG, Carvalho AF, Costa FF, Savino W, Reis LF. Identification, structural characterization, and tissue distribution of Tsg-5: a new TNF-stimulated gene. Genes Immun. 4: 298-311 (2003). *
Abreu JR, Grabiec AM, Krausz S, Spijker R, Burakowski T, Maslinski W, Eldering E, Tak PP, Reedquist KA. The presumed hyporesponsive behavior of rheumatoid arthritis T lymphocytes can be attributed to spontaneous ex vivo apoptosis rather than defects in T cell receptor signaling. J. Immunol. Jun 12 [Epub ahead of print] (2009).
Abreu MT. Immunologic regulation of Toll-like receptors in gut epithelium. Curr. Opin. Gastroenterol. 19: 559-564 (2003).
Abreu MT. The pathogenesis of inflammatory bowel disease: translational implications for clinicians. Curr. Gastroenterol. Rep. 4: 481-489 (2002).
Abreu MT, Arnold ET, Thomas LS, Gonsky R, Zhou Y, Hu B, Arditi M. TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells. J. Biol. Chem. 277: 20431-20437 (2002). *
Abreu MT, Plevy S, Sands BE, Weinstein R. Selective leukocyte apheresis for the treatment of inflammatory bowel disease. J. Clin. Gastroenterol. 41: 874-888 (2007).
Abreu MT, Taylor KD, Lin YC, Hang T, Gaiennie J, Landers CJ, Vasiliauskas EA, Kam LY, Rojany M, Papadakis KA, Rotter JI, Targan SR, Yang H. Mutations in NOD2 are associated with fibrostenosing disease in patients with Crohn's disease. Gastroenterology 123: 679-688 (2002). *
Abreu MT, Yang H. Is genetic testing in IBD ready for prime time? Am. J. Gastroenterol. 99: 316-318 (2004). *
Abu-Abed S, Dolle P, Metzger D, Beckett B, Chambon P, Petkovich M. The retinoic acid-metabolizing enzyme, CYP26A1, is essential for normal hindbrain patterning, vertebral identity, and development of posterior structures. Genes Dev. 15: 226-240 (2001). *
Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dolle P. Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech. Dev. 110: 173-177 (2002). *
Acevedo-Suarez CA, Hulbert C, Woodward EJ, Thomas JW. Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes. J. Immunol. 174: 827-833 (2005). *
Achiron A, Gurevich M, Snir Y, Segal E, Mandel M. Zinc-ion binding and cytokine activity regulation pathways predicts outcome in relapsing-remitting multiple sclerosis. Clin. Exp. Immunol. 149: 235-242 (2007). *
Achkar JP, Dassopoulos T, Silverberg MS, Tuvlin JA, Duerr RH, Brant SR, Siminovitch K, Reddy D, Datta LW, Bayless TM, Zhang L, Barmada MM, Rioux JD, Steinhart AH, McLeod RS, Griffiths AM, Cohen Z, Yang H, Bromfield GP, Schumm P, Hanauer SB, Cho JH, et al. Phenotype-stratified genetic linkage study demonstrates that IBD2 is an extensive ulcerative colitis locus. Am. J. Gastroenterol. 101: 572-580 (2006). *
Ackerman LS. Sex hormones and the genesis of autoimmunity. Arch. Dermatol. 142: 371-376 (2006). *
Ackert-Bicknell C, Rosen C. The genetics of PPARG and the skeleton. PPAR Res. 2006: 93258 (2006). *
Acton JD, Wilmott RW. Phenotype of CF and the effects of possible modifier genes. Paediatr. Respir. Rev. 2: 332-339 (2001).
Adachi M, Inoko A, Hata M, Furuse K, Umeda K, Itoh M, Tsukita S. Normal establishment of epithelial tight junctions in mice and cultured cells lacking expression of ZO-3, a tight-junction MAGUK protein. Mol. Cell. Biol. 26: 9003-9015 (2006). *
Adachi M, Kurotani R, Morimura K, Shah Y, Sanford M, Madison BB, Gumucio DL, Marin HE, Peters JM, Young HA, Gonzalez FJ. PPARgamma in colonic epithelial cells protects against experimental inflammatory bowel disease. Gut 55: 1104-1113 (2006). *
Adachi T, Toishi T, Takashima E, Hara H. Infliximab neutralizes the suppressive effect of TNF-alpha on expression of extracellular-superoxide dismutase in vitro. Biol. Pharm. Bull. 29: 2095-2098 (2006). *
Adam R, Sturrock RD, Gracie JA. TLR4 mutations (Asp299Gly and Thr399Ile) are not associated with ankylosing spondylitis. Ann. Rheum. Dis. 65: 1099-1101 (2006). *
Adam-Stitah S, Penna L, Chambon P, Rochette-Egly C. Hyperphosphorylation of the retinoid X receptor alpha by activated c-Jun NH2-terminal kinases. J. Biol. Chem. 274: 18932-18941 (1999). *
Adamiec R, Gacka M, Dobosz T, Szymaniec S, Bednarska-Chabowska D, Sadakierska-Chudy A. Stimulation of the peroxisome proliferator-activated receptor gamma (PPARgamma) and the expression of selected blood monocyte cytokine genes in diabetic macroangiopathy. Atherosclerosis 194: e108-e115 (2007).
Adamkiewicz J, Kaddatz K, Rieck M, Wilke B, Muller-Brusselbach S, Muller R. Proteomic profile of mouse fibroblasts with a targeted disruption of the peroxisome proliferator activated receptor-beta/delta gene. Proteomics 7: 1208-1216 (2007). *
Adamo KB, Dent R, Langefeld CD, Cox M, Williams K, Carrick KM, Stuart JS, Sundseth SS, Harper ME, McPherson R, Tesson F. Peroxisome proliferator-activated receptor gamma 2 and acyl-CoA synthetase 5 polymorphisms influence diet response. Obesity (Silver Spring) 15: 1068-1075 (2007). *
Adamopoulos AB. Inflammatory bowel disease (IBD) and the liver. Annals of Gastroenterology 19: 146-151 (2006). *
Adams DH. Mucosal lymphocytes in the pathogenesis of the hepatic complications of inflammatory bowel disease. Clin. Med. 8: 28-29 (2008). *
Adams DH, Afford SC. Effector mechanisms of nonsuppurative destructive cholangitis in graft-versus-host disease and allograft rejection. Semin. Liver Dis. 25: 281-297 (2005).
Adams DH, Eksteen B, Grant A, Miles A, Lalor T. The molecular regulation of lymphocyte homing between the liver and gut. Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 54 (2005). *
Adams M, Lucock M, Stuart J, Fardell S, Baker K, Ng X. Preliminary evidence for involvement of the folate gene polymorphism 19bp deletion-DHFR in occurrence of autism. Neurosci. Lett. 422: 24-29 (2007).
Adams PC. Hemochromatosis. Clin. Liver Dis. 8: 735-753, vii (2004).
Adams PC, Walker AP, Acton RT. A primer for predicting risk of disease in HFE-linked hemochromatosis. Genet. Test. 5: 311-316 (2001).
Adamson AW, Dreesen TD, Tekle M, Tang C, Cho HP, Clarke SD, Gettys TW. A newly discovered member of the fatty acid desaturase gene family: a non-coding, antisense RNA gene to Delta5-desaturase. Prostaglandins Leukot. Essent. Fatty Acids 75: 97-106 (2006). *
Adamson KA, Pearce SH, Lamb JR, Seckl JR, Howie SE. A comparative study of mRNA and protein expression of the autoimmune regulator gene (Aire) in embryonic and adult murine tissues. J. Pathol. 202: 180-187 (2004). *
Adamzik M, Frey UH, Bitzer K, Jakob H, Baba HA, Schmieder RE, Schneider MP, Heusch G, Peters J, Siffert W. A novel-1364A/C aquaporin 5 gene promoter polymorphism influences the responses to salt loading of the renin-angiotensin-aldosterone system and of blood pressure in young healthy men. Basic Res. Cardiol. 103: 598-610 (2008).
Adarichev VA, Vermes C, Hanyecz A, Ludanyi K, Tunyogi-Csapo M, Finnegan A, Mikecz K, Glant TT. Antigen-induced differential gene expression in lymphocytes and gene expression profile in synovium prior to the onset of arthritis. Autoimmunity 39: 663-673 (2006).
Adarichev VA, Vermes C, Hanyecz A, Mikecz K, Bremer EG, Glant TT. Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation. Arthritis Res. Ther. 7: R196-R207 (2005). *
Adcock IM, Caramori G. Cross-talk between pro-inflammatory transcription factors and glucocorticoids. Immunol. Cell Biol. 79: 376-384 (2001).
Adcock IM, Ito K, Barnes PJ. Histone deacetylation: an important mechanism in inflammatory lung diseases. COPD 2: 445-455 (2005).
Ademokun A, Turner M. Regulation of B-cell differentiation by microRNAs and RNA-binding proteins. Biochem. Soc. Trans. 36: 1191-1193 (2008). *
Adib-Conquy M, Pedron T, Petit-Bertron AF, Tabary O, Corvol H, Jacquot J, Clement A, Cavaillon JM. Neutrophils in cystic fibrosis display a distinct gene expression pattern. Mol. Med. 14: 36-44 (2008). *
Adibi SA. Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. Am. J. Physiol. Gastrointest. Liver Physiol. 285: G779-G788 (2003). *
Adida A, Spener F. Adipocyte-type fatty acid-binding protein as inter-compartmental shuttle for peroxisome proliferator activated receptor gamma agonists in cultured cell. Biochim. Biophys. Acta 1761: 172-181 (2006). *
Adisen E, Gulekon A, Erdem O, Dursun A, Gurer M. The effects of calcipotriol and methylprednisolone aseponate on bcl-2, p53 and ki-67 expression in psoriasis. J. Eur. Acad. Dermatol. Venereol. 20: 527-533 (2006). *
Adler AS, Kawahara TL, Segal E, Chang HY. Reversal of aging by NFkappaB blockade. Cell Cycle 7: 556-559 (2008). *
Adler EM. IL-2 antagonizes Th17 differentiation. Sci. STKE 379: tw103 (2007).
Adriaansen J, Fallaux FJ, de Cortie CJ, Vervoordeldonk MJ, Tak PP. Local delivery of beta interferon using an adeno-associated virus type 5 effectively inhibits adjuvant arthritis in rats. J. Gen. Virol. 88: 1717-1721 (2007). *
Adriaansen J, Khoury M, de Cortie CJ, Fallaux FJ, Bigey P, Scherman D, Gould DJ, Chernajovsky Y, Apparailly F, Jorgensen C, Vervoordeldonk MJ, Tak P. Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent. Ann. Rheum. Dis. 66: 1143-1150 (2007). *
Adriaansen J, Kuhlman RR, Holten JV, Kaynor C, Vervoordeldonk MJ, Tak PP. Intraarticular interferon-beta gene therapy ameliorates adjuvant arthritis in rats. Hum. Gene Ther. 17: 985-996 (2006).
Adriaansen J, Tas SW, Klarenbeek PL, Bakker AC, Apparailly F, Firestein GS, Jorgensen C, Vervoordeldonk MJ, Tak PP. Enhanced gene transfer to arthritic joints using adeno-associated virus type 5: implications for intra-articular gene therapy. Ann. Rheum. Dis. 64: 1677-1684 (2005). *
Adriaansen J, Vervoordeldonk MJ, Tak PP. Gene therapy as a therapeutic approach for the treatment of rheumatoid arthritis: innovative vectors and therapeutic genes. Rheumatology (Oxford) 45: 656-668 (2006). *
Adriani M, Aoki J, Horai R, Thornton AM, Konno A, Kirby M, Anderson SM, Siegel RM, Candotti F, Schwartzberg PL. Impaired in vitro regulatory T cell function associated with Wiskott-Aldrich syndrome. Clin. Immunol. 124: 41-48 (2007). *
Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is down-regulated by interleukin-1beta in articular chondrocytes. Arthritis Res. Ther. 9: R31 (2007). *
Aflatoonian R, Tuckerman E, Elliott SL, Bruce C, Aflatoonian A, Li TC, Fazeli A. Menstrual cycle-dependent changes of Toll-like receptors in endometrium. Hum. Reprod. 22: 586-593 (2007).
Afman L, Muller M. Nutrigenomics: from molecular nutrition to prevention of disease. J. Am. Diet. Assoc. 106: 569-576 (2006).
Agalliu I, Suuriniemi M, Prokunina-Olsson L, Johanneson B, Collins FS, Stanford JL, Ostrander EA. Evaluation of a variant in the transcription factor 7-like 2 (TCF7L2) gene and prostate cancer risk in a population-based study. Prostate 68: 740-747 (2008).
Agarwal K, Czaja AJ, Donaldson PT. A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis. Tissue Antigens 69: 227-235 (2007). *
Agarwal RK, Horai R, Viley AM, Silver PB, Grajewski RS, Bo Su S, Yazdani AT, Zhu W, Kronenberg M, Murray PJ, Rutschman RL, Chan CC, Caspi RR. Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms. J. Immunol. 180: 5423-5429 (2008). *
Agassandian M, Miakotina OL, Andrews M, Mathur SN, Mallampalli RK. P. aeruginosa and sPLA2 IB stimulate ABCA1-mediated phospholipid efflux via ERK-activation of PPARalpha/RXR. Biochem. J. 403: 409-420 (2007). *
Agematsu K, Futatani T, Hokibara S, Kobayashi N, Takamoto M, Tsukada S, Suzuki H, Koyasu S, Miyawaki T, Sugane K, Komiyama A, Ochs HD. Absence of memory B cells in patients with common variable immunodeficiency. Clin. Immunol. 103: 34-42 (2002). *
Agez L, Laurent V, Pevet P, Masson-Pevet M, Gauer F. Melatonin affects nuclear orphan receptors mRNA in the rat suprachiasmatic nuclei. Neuroscience 144: 522-530 (2007).
Aggarwal BB, Sethi G, Nair A, Ichikawa H. Nuclear factor-kB: a holy grail in cancer prevention and therapy. Current Signal Transduction Therapy 1: 25-52 (2006). *
Aggarwal BB, Shishodia S, Sandur SK, Pandey MK, Sethi G. Inflammation and cancer: how hot is the link? Biochem. Pharmacol. 72: 1605-1621 (2006). *
Aggarwal BB, Takada Y, Oommen OV. From chemoprevention to chemotherapy: common targets and common goals. Expert Opin. Investig. Drugs 13: 1327-1338 (2004).
Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J. Biol. Chem. 278: 1910-1914 (2003). *
Aggarwal S, Xie MH, Maruoka M, Foster J, Gurney AL. Acinar cells of the pancreas are a target of interleukin-22. J. Interferon Cytokine Res. 21: 1047-1053 (2001).
Agostini C, Cabrelle A, Calabrese F, Bortoli M, Scquizzato E, Carraro S, Miorin M, Beghe B, Trentin L, Zambello R, Facco M, Semenzato G. Role for CXCR6 and its ligand CXCL16 in the pathogenesis of T-cell alveolitis in sarcoidosis. Am. J. Respir. Crit. Care Med. 172: 1290-1298 (2005). *
Agrawal D, Chen T, Irby R, Quackenbush J, Chambers AF, Szabo M, Cantor A, Coppola D, Yeatman TJ. Osteopontin identified as colon cancer tumor progression marker. C.R. Biol. 326: 1041-1043 (2003).
Agrawal S, Dimitrova N, Prasthani N, Udayakumar K, Sailakshmi S, Sriram S, Manjusha N, Sengupta U. T2D-Db: an integrated platform to study the molecular basis of type 2 diabetes. BMC Genomics 9: 320 (2008). *
Agrawal S, Srivastava R, Sharma B, Pandya S, Misra R, Aggarwal A. IL1RN*2 allele of IL-1receptor antagonist VNTR polymorphism is associated with susceptibility to anklyosing spondylitis in Indian patients. Clin. Rheumatol. 27: 573-576 (2008). *
Aguiari G, Varani K, Bogo M, Mangolini A, Vincenzi F, Durante C, Gessi S, Sacchetto V, Catizone L, Harris P, Rizzuto R, Borea PA, Del Senno L. Deficiency of polycystic kidney disease-1 gene (PKD1) expression increases A(3) adenosine receptors in human renal cells: implications for cAMP-dependent signalling and proliferation of PKD1-mutated cystic cells. Biochim. Biophys. Acta Mar 11 [Epub ahead of print] (2009). *
Aguilar RP, Genta S, Oliveros L, Anzulovich A, Gimenez MS, S Sanchez S. Vitamin A deficiency injures liver parenchyma and alters the expression of hepatic extracellular matrix. J. Appl. Toxicol. 29: 214-222 (2009). *
Aguilar-Martinez P, Bismuth M, Picot MC, Thelcide C, Pageaux GP, Blanc F, Blanc P, Schved JF, Larrey D. Variable phenotypic presentation of iron overload in H63D homozygotes: are genetic modifiers the cause? Gut 48: 836-842 (2001). *
Aguilera O, Pena C, Garcia JM, Larriba MJ, Ordonez-Moran P, Navarro D, Barbachano A, de Silanes IL, Ballestar E, Fraga MF, Esteller M, Gamallo C, Bonilla F, Gonzalez-Sancho JM, Munoz A. The Wnt antagonist DICKKOPF-1 gene is induced by 1alpha,25-dihydroxyvitamin D3 associated to the differentiation of human colon cancer cells. Carcinogenesis 28: 1877-1884 (2007). *
Aguillon G JC, Cruzat C A, Contreras-Levicoy J, Dotte G A, Pesce R B, Aravena MO, Salazar A L, Catalan M D, Abello C P, Aguirre D A, Llanos M C, Cuchacovich TM. Emergent therapies for rheumatoid arthritis. Rev. Med. Chil. 133: 969-976 (2005).
Aguillon JC, Cruzat A, Aravena O, Salazar L, Llanos C, Cuchacovich M. Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? Immunobiology 211: 75-84 (2006).
Aguillon JC, Cruzat A, Cuenca J, Cuchacovich M. Tumor necrosis factor alpha genetic polymorphism as a risk factor in disease. Rev. Med. Chil. 130: 1043-1050 (2002).
Aharoni R, Kayhan B, Brenner O, Domev H, Labunskay G, Arnon R. Immunomodulatory therapeutic effect of glatiramer acetate on several murine models of inflammatory bowel disease. J. Pharmacol. Exp. Ther. 318: 68-78 (2006). *
Ahluwalia A, Clodfelter KH, Waxman DJ. Sexual dimorphism of rat liver gene expression: regulatory role of growth hormone revealed by deoxyribonucleic acid microarray analysis. Mol. Endocrinol. 18: 747-760 (2004). *
Ahluwalia J, Tinker A, Clapp LH, Duchen MR, Abramov AY, Pope S, Nobles M, Segal AW. The large-conductance Ca2+-activated K+ channel is essential for innate immunity. Nature 427: 853-858 (2004). *
Ahluwalia TS, Ahuja M, Rai TS, Kohli HS, Sud K, Bhansali A, Khullar M. Endothelial nitric oxide synthase gene haplotypes and diabetic nephropathy among Asian Indians. Mol. Cell. Biochem. 314: 9-17 (2008). *
Ahmad R, Qureshi HY, El Mabrouk M, Sylvester J, Ahmad M Dr, Zafarullah M. Inhibition of interleukin 1-induced matrix metalloproteinase 13 expression in human chondrocytes by interferon gamma. Ann. Rheum. Dis. 66: 782-789 (2007). *
Ahmad R, Sylvester J, Zafarullah M. MyD88, IRAK1 and TRAF6 knockdown in human chondrocytes inhibits interleukin-1-induced matrix metalloproteinase-13 gene expression and promoter activity by impairing MAP kinase activation. Cell. Signal. 19: 2549-2557 (2007). *
Ahmad T, Marshall SE, Mulcahy-Hawes K, Orchard T, Crawshaw J, Armuzzi A, Neville M, van Heel D, Barnardo M, Welsh KI, Jewell DP, Bunce M. High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility. Tissue Antigens 60: 164-179 (2002). *
Ahmad W, Panteleyev AA, Christiano AM. The molecular basis of congenital atrichia in humans and mice: mutations in the hairless gene. J. Investig. Dermatol. Symp. Proc. 4: 240-243 (1999). *
Ahmad YA, Bruce IN. Genetic epidemiology: systemic lupus erythematosus. Arthritis Res. 3: 331-336 (2001). *
Ahmadi KR, Lanchbury JS, Reed P, Chiano M, Thompson D, Galley M, Line A, Lank E, Wong HJ, Strachan D, Spector TD. Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels. Genes Immun. 4: 289-297 (2003). *
Ahmed MB, Belhadj Hmida N, Moes N, Buyse S, Abdeladhim M, Louzir H, Cerf-Bensussan N. IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway. J. Immunol. 182: 6763-6770 (2009).
Ahmed RA, Murao K, Imachi H, Yu X, Li J, Wong NC, Ishida T. Human scavenger receptor class B type 1 is regulated by activators of peroxisome proliferators-activated receptor-gamma in hepatocytes. Endocrine 35: 233-242 (2009).
Ahmed SS, Tan FK. Identification of novel targets in scleroderma: update on population studies, cDNA arrays, SNP analysis, and mutations. Curr. Opin. Rheumatol. 15: 766-771 (2003).
Ahmed TA, Buzzelli MD, Lang CH, Capen JB, Shumate ML, Navaratnarajah M, Nagarajan M, Cooney RN. Interleukin-6 inhibits growth hormone-mediated gene expression in hepatocytes. Am. J .Physiol. Gastrointest. Liver Physiol. 292: G1793-G1803 (2007). *
Ahmed W, Orasanu G, Nehra V, Asatryan L, Rader DJ, Ziouzenkova O, Plutzky J. High-density lipoprotein hydrolysis by endothelial lipase activates PPARalpha. A candidate mechanism for high-density lipoprotein-mediated repression of leukocyte adhesion. Circ. Res. 98: 490-498 (2006). *
Ahn D, Crawley S, Hokari R, Kato S, Yang S, Li J, Kim Y. TNF-alpha activates MUC2 transcription via NF-kappaB but inhibits via JNK activation. Cell. Physiol. Biochem. 15: 29-40 (2005). *
Ahn J, Gammon MD, Santella RM, Gaudet MM, Britton JA, Teitelbaum SL, Terry MB, Neugut AI, Eng SM, Zhang Y, Garza C, Ambrosone CB. Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk. Carcinogenesis 27: 1876-1882 (2006). *
Ahn S, Lee G, Yang SJ, Lee D, Lee S, Shin HS, Kim MC, Lee KN, Palmer DC, Theoret MR, Jenkinson EJ, Anderson G, Restifo NP, Kim MG. TSCOT (+) thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS Biol. 6: e191 (2008). *
Ahn SH, Shah YM, Inoue J, Morimura K, Kim I, Yim S, Lambert G, Kurotani R, Nagashima K, Gonzalez FJ, Inoue Y. Hepatocyte nuclear factor 4 in the intestinal epithelial cells protects against inflammatory bowel disease. Inflamm. Bowel Dis. 14: 908-920 (2008).
Aho TL, Sandholm J, Peltola KJ, Ito Y, Koskinen PJ. Pim-1 kinase phosphorylates RUNX family transcription factors and enhances their activity. BMC Cell Biol. 7: 21 (2006). *
Ahrendt M, Hammerschmidt SI, Pabst O, Pabst R, Bode U. Stromal cells confer lymph node-specific properties by shaping a unique microenvironment influencing local immune responses. J. Immunol. 181: 1898-1907 (2008).
Ahrendt SA, Rashid A, Chow JT, Eisenberger CF, Pitt HA, Sidransky D. p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer. J. Hepatobiliary Pancreat. Surg. 7: 426-431 (2000).
Ahrens R, Waddell A, Seidu L, Blanchard C, Carey R, Forbes E, Lampinen M, Wilson T, Cohen E, Stringer K, Ballard E, Munitz A, Xu H, Lee N, Lee JJ, Rothenberg ME, Denson L, Hogan SP. Intestinal macrophage/epithelial cell-derived CCL11/eotaxin-1 mediates eosinophil recruitment and function in pediatric ulcerative colitis. J. Immunol. 181: 7390-7399 (2008).
Ahuja HS, Szanto A, Nagy L, Davies PJ. The retinoid X receptor and its ligands: versatile regulators of metabolic function, cell differentiation and cell death. J. Biol. Regul. Homeost. Agents 17: 29-45 (2003).
Ahuja J, Kampani K, Datta S, Wigdahl B, Flaig KE, Jain P. Use of human antigen presenting cell gene array profiling to examine the effect of human T-cell leukemia virus type 1 Tax on primary human dendritic cells. J. Neurovirol. 12: 47-59 (2006).
Ahuja V, Dieckgraefe B, Anant S. Molecular biology of the small intestine. Curr. Opin. Gastroenterol. 22: 90-94 (2006).
Ai ZL, Chen DF. The significance and effects of liver X receptor alpha in nonalcoholic fatty liver disease in rats. Zhonghua Gan Zang Bing Za Zhi 15: 127-130 (2007).
Aida K, Tawata M, Negishi M, Onaya T. Mouse glycine N-methyltransferase is sexually dimorphic and regulated by growth hormone. Horm. Metab. Res. 29: 646-649 (1997).
Aigner E, Theurl I, Theurl M, Lederer D, Haufe H, Dietze O, Strasser M, Datz C, Weiss G. Pathways underlying iron accumulation in human nonalcoholic fatty liver disease. Am. J. Clin. Nutr. 87: 1374-1383 (2008). *
Aihara K, Azuma H, Matsumoto T. Vitamin D-vitamin D receptor system regulates antithrombogenicity in vivo. Clin. Calcium 16: 1173-1179 (2006).
Ainola M, Mandelin J, Liljestrom M, Konttinen YT, Salo J. Imbalanced expression of RANKL and osteoprotegerin mRNA in pannus tissue of rheumatoid arthritis. Clin. Exp. Rheumatol. 26: 240-246 (2008).
Ainsworth DM, Wagner B, Franchini M, Grunig G, Erb HN, Tan JY. Time-dependent alterations in gene expression of interleukin-8 in the bronchial epithelium of horses with recurrent airway obstruction. Am. J. Vet. Res. 67: 669-677 (2006).
Aird RE, Thomson M, Macpherson JS, Thurston DE, Jodrell DI, Guichard SM. ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136. Pharmacogenomics J. 8: 289-296 (2008).
Aitken AE, Morgan E. Gene-specific effects of inflammatory cytokines on cytochrome P4502C, 2B6 and 3A4 mRNA levels in human hepatocytes. Drug Metab. Dispos. 35: 1687-1693 (2007). *
Aittoniemi J, Soranummi H, Rovio AT, Hurme M, Pessi T, Nieminen M, Karjalainen J. Mannose-binding lectin 2 (MBL2) gene polymorphism in asthma and atopy among adults. Clin. Exp. Immunol. 142: 120-124 (2005). *
Aizu T, Tamai K, Nakano H, Rokunohe D, Toyomaki Y, Uitto J, Sawamura D. Calcineurin/NFAT-dependent regulation of 230-kDa bullous pemphigoid antigen (BPAG1) gene expression in normal human epidermal keratinocytes. J. Dermatol. Sci. 51: 45-51 (2008).
Ajima R, Akiyama T, Usui M, Yoneda M, Yoshida Y, Nakamura T, Minowa O, Noda M, Tanaka S, Noda T, Yamamoto T. Osteoporotic bone formation in mice lacking Tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation. FEBS Lett. 582: 1313-1318 (2008). *
Ajjan RA, Weetman AP. New understanding of the role of cytokines in the pathogenesis of Graves' ophthalmopathy. J. Endocrinol. Invest. 27: 237-245 (2004).
Ajonuma LC, Chan PK, Ng EH, Fok KL, Wong CH, Tsang LL, Tang XX, Ho LS, Lau MC, Chung CM, He Q, Huang HY, Yang DZ, Rowlands DK, Chung YW, Chan HC. Involvement of cystic fibrosis transmembrane conductance regulator (CFTR) in the pathogenesis of hydrosalpinx induced by Chlamydia trachomatis infection. J. Obstet. Gynaecol. Res. 34: 923-930 (2008).
Ajonuma LC, Tsang LL, Zhang GH, Wong CH, Lau MC, Ho LS, Rowlands DK, Zhou CX, Ng CP, Chen J, Xu PH, Zhu JX, Chung YW, Chan HC. Estrogen-induced abnormally high CFTR expression results in ovarian hyperstimulation syndrome. Mol. Endocrinol. 19: 3038-3044 (2005). *
Akaishi H, Takeda K, Kaisho T, Shineha R, Satomi S, Takeda J, Akira S. Defective IL-2-mediated IL-2 receptor alpha chain expression in Stat3-deficient T lymphocytes. Int. Immunol. 10: 1747-1751 (1998). *
Akaogi J, Nozaki T, Satoh M, Yamada H. Role of PGE2 and EP receptors in the pathogenesis of rheumatoid arthritis and as a novel therapeutic strategy. Endocr. Metab. Immune Disord. Drug Targets 6: 383-394 (2006).
Akar CA, Feinstein DL. Modulation of inducible nitric oxide synthase expression by sumoylation. J. Neuroinflammation 6: 12 (2009).
Akazawa A, Sakaida I, Higaki S, Kubo Y, Uchida K, Okita K. Increased expression of tumor necrosis factor-alpha messenger RNA in the intestinal mucosa of inflammatory bowel disease, particularly in patients with disease in the inactive phase. J. Gastroenterol. 37: 345-353 (2002). *
Akbiyik F, Cinar K, Demirpence E, Ozsullu T, Tunca R, Haziroglu R, Yurdaydin C, Uzunalimoglu O, Bozkaya H. Ligand-induced expression of peroxisome proliferator-activated receptor alpha and activation of fatty acid oxidation enzymes in fatty liver. Eur. J. Clin. Invest. 34: 429-435 (2004).
Akesson LS, Duffy DL, Phelps SC, Thompson PJ, Kedda MA. A polymorphism in the promoter region of the human interleukin-16 gene is not associated with asthma or atopy in an Australian population. Clin. Exp. Allergy 35: 327-331 (2005). *
Akgul S, Erbil Y, Giris M, Alis H, Yanik BT, Olgac V, Toker GA. The effect of octreotide on pancreatic damage in TNBS-induced colitis. Surg. Innov. 13: 102-108 (2006).
Akhmetshina A, Dees C, Busch N, Beer J, Sarter K, Zwerina J, Zimmer A, Distler O, Schett G, Distler JH. The cannabinoid receptor CB2 exerts antifibrotic effects in experimental dermal fibrosis. Arthritis Rheum. 60: 1129-1136 (2009). *
Akiyama TE, Sakai S, Lambert G, Nicol CJ, Matsusue K, Pimprale S, Lee YH, Ricote M, Glass CK, Brewer HB Jr, Gonzalez FJ. Conditional disruption of the peroxisome proliferator-activated receptor gamma gene in mice results in lowered expression of ABCA1, ABCG1, and apoE in macrophages and reduced cholesterol efflux. Mol. Cell. Biol. 22: 2607-2619 (2002). *
Akiyama TE, Ward JM, Gonzalez FJ. Regulation of the liver fatty acid-binding protein gene by hepatocyte nuclear factor 1alpha (HNF1alpha). Alterations in fatty acid homeostasis in HNF1alpha-deficient mice. J. Biol. Chem. 275: 27117-27122 (2000). *
Akiyoshi H, Hatakeyama S, Pitkanen J, Mouri Y, Doucas V, Kudoh J, Tsurugaya K, Uchida D, Matsushima A, Oshikawa K, Nakayama KI, Shimizu N, Peterson P, Matsumoto M. Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner. J. Biol. Chem. 279: 33984-33991 (2004). *
Akkad DA, Arning L, Ibrahim SM, Epplen JT. Sex specifically associated promoter polymorphism in multiple sclerosis affects interleukin 4 expression levels. Genes Immun. 8: 703-706 (2007). *
Akkad DA, Kruse N, Arning L, Gold R, Epplen JT. Genomic NGFB variation and multiple sclerosis in a case control study. BMC Med. Genet. 9: 107 (2008). *
Akkiprik M, Celikel CA, Dusunceli F, Sonmez O, Gulluoglu BM, Sav A, Ozer A. Relationship between overexpression of ras p21 oncoprotein and K-ras codon 12 and 13 mutations in Turkish colorectal cancer patients. Turk. J. Gastroenterol. 19: 22-27 (2008). *
Aksentijevich I, Nowak M, Mallah M, Chae JJ, Watford WT, Hofmann SR, Stein L, Russo R, Goldsmith D, Dent P, Rosenberg HF, Austin F, Remmers EF, Balow JE Jr, Rosenzweig S, Komarow H, Shoham NG, Wood G, Jones J, Mangra N, Carrero H, Adams BS, et al. De novo CIAS1 mutations, cytokine activation, and evidence for genetic heterogeneity in patients with neonatal-onset multisystem inflammatory disease (NOMID): a new member of the expanding family of pyrin-associated autoinflammatory diseases. Arthritis Rheum. 46: 3340-3348 (2002). *
Aksoy E, Albarani V, Nguyen M, Laes JF, Ruelle JL, De Wit D, Willems F, Goldman M, Goriely S. Interferon regulatory factor 3-dependent responses to lipopolysaccharide are selectively blunted in cord blood cells. Blood 109: 2887-2893 (2007). *
Al-Alem U, Li C, Forey N, Relouzat F, Fondaneche MC, Tavtigian SV, Wang ZQ, Latour S, Yin L. Impaired Ig class switch in mice deficient for the X-linked lymphoproliferative disease gene Sap. Blood 106: 2069-2075 (2005). *
Al-Dosari MS, Knapp JE, Liu D. Activation of human CYP2C9 promoter and regulation by CAR and PXR in mouse liver. Mol. Pharm. 3: 322-328 (2006). *
Al-Falahi Y, Sand KL, Knudsen E, Damaj BB, Rolin J, Maghazachi AA. Splenic natural killer cell activity in two models of experimental neurodegenerative diseases. J. Cell. Mol. Med. Dec 29 [Epub ahead of print] (2008). *
Al-Hasani H, Joost HG. Nutrition-/diet-induced changes in gene expression in white adipose tissue. Best Pract. Res. Clin. Endocrinol. Metab. 19: 589-603 (2005).
Al-Izki S, Pryce G, Giovannoni G, Baker D. Evaluating potential therapies for bladder dysfunction in a mouse model of multiple sclerosis with high-resolution ultrasonography. Mult. Scler. May 22 [Epub ahead of print] (2009).
Al-Kandari W, Jambunathan S, Navalgund V, Koneni R, Freer M, Parimi N, Mudhasani R, Fontes JD. ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription. Mol. Immunol. 44: 311-321 (2007). *
Al-Kandari W, Koneni R, Navalgund V, Aleksandrova A, Jambunathan S, Fontes JD. The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription. J. Mol. Biol. 369: 1175-1187 (2007). *
Al-Khalidi JA, Czaja AJ. Current concepts in the diagnosis, pathogenesis, and treatment of autoimmune hepatitis. Mayo Clin. Proc. 76: 1237-1252 (2001). *
Al-Khalili L, Bouzakri K, Glund S, Lonnqvist F, Koistinen HA, Krook A. Signaling specificity of interleukin-6 action on glucose and lipid metabolism in skeletal muscle. Mol. Endocrinol. 20: 3364-3375 (2006). *
Al-Refu K, Goodfield M. Hair follicle stem cells in the pathogenesis of the scarring process in cutaneous lupus erythematosus. Autoimmun. Rev. 8: 474-477 (2009).
Al-Saleh J, el-Eissawy S. The role of T helper cell subsets in pathogenesis of systemic lupus erythematosus and their relation to disease activity. Egypt. J. Immunol. 13: 41-48 (2006).
Al-Toma A, Goerres MS, Meijer JW, von Blomberg BM, Wahab PJ, Kerckhaert JA, Mulder CJ. Cladribine therapy in refractory celiac disease with aberrant T cells. Clin. Gastroenterol. Hepatol. 4: 1322-1327 (2006).
Ala A, Schilsky ML. Inherited metabolic liver disease. Curr. Opin. Gastroenterol. 20: 198-207 (2004).
Alaez C, Gazit E, Ibarrola B, Yaron M, Livneh A, Avishai O, Gorodezky C. Distribution of HLA-B27 subtypes in ankylosing spondylitis in an Israeli population. Arch. Med. Res. 38: 452-455 (2007).
Alaez C, Vazquez-Garcia MN, Gorodezky C. DQA1 and DQB1 promoter diversity and linkage disequilibrium with class II haplotypes in Mexican Mestizo population. Genes Immun. 2: 216-221 (2001). *
Alagarasu K, Selvaraj P, Swaminathan S, Raghavan S, Narendran G, Narayanan PR. Mannose binding lectin gene variants and susceptibility to tuberculosis in HIV-1 infected patients of South India. Tuberculosis (Edinb.) 87: 535-543 (2007).
Alaminos M, Gonzalez-Andrades M, Munoz-Avila JI, Garzon I, Sanchez-Quevedo MC, Campos A. Volumetric and ionic regulation during the in vitro development of a corneal endothelial barrier. Exp. Eye Res. 86: 758-769 (2008).
Alarcon-Aguilar FJ, Almanza-Perez J, Blancas G, Angeles S, Garcia-Macedo R, Roman R, Cruz M. Glycine regulates the production of pro-inflammatory cytokines in lean and monosodium glutamate-obese mice. Eur. J. Pharmacol. 599: 152-158 (2008). *
Alarcon-Riquelme ME. Recent advances in the genetics of autoimmune diseases. Ann. N. Y. Acad. Sci. 1110: 1-9 (2007). *
Alavi K, Schwartz MZ, Palazzo JP, Prasad R. Treatment of inflammatory bowel disease in a rodent model with the intestinal growth factor glucagon-like peptide-2. J. Pediatr. Surg. 35: 847-851 (2000).
Alaynick WA. Nuclear receptors, mitochondria and lipid metabolism. Mitochondrion 8: 329-337 (2008).
Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J. Immunol. 162: 494-502 (1999). *
Albanesi C, De Pita O, Girolomoni G. Resident skin cells in psoriasis: a special look at the pathogenetic functions of keratinocytes. Clin. Dermatol. 25: 581-688 (2007).
Albanesi C, Scarponi C, Cavani A, Federici M, Nasorri F, Girolomoni G. Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. J. Invest. Dermatol. 115: 81-87 (2000). *
Albano E. Oxidative mechanisms in the pathogenesis of alcoholic liver disease. Mol. Aspects Med. 29: 9-16 (2008).
Alberati-Giani D, Malherbe P, Ricciardi-Castagnoli P, Kohler C, Denis-Donini S, Cesura AM. Differential regulation of indoleamine 2,3-dioxygenase expression by nitric oxide and inflammatory mediators in IFN-gamma-activated murine macrophages and microglial cells. J. Immunol. 159: 419-426 (1997).
Albert CJ, Anbukumar DS, Monda JK, Eckelkamp JT, Ford DA. Myocardial lipidomics. Developments in myocardial nuclear lipidomics. Front. Biosci. 12: 2750-2760 (2007).
Albert PJ, Proal AD, Marshall TG. Vitamin D: the alternative hypothesis. Autoimmun. Rev. 8: 639-644 (2009).
Alberti S, Schuster G, Parini P, Feltkamp D, Diczfalusy U, Rudling M, Angelin B, Bjorkhem I, Pettersson S, Gustafsson JA. Hepatic cholesterol metabolism and resistance to dietary cholesterol in LXRbeta-deficient mice. J. Clin. Invest. 107: 565-573 (2001). *
Albrecht U, Yang X, Asselta R, Keitel V, Tenchini ML, Ludwig S, Heinrich PC, Haussinger D, Schaper F, Bode JG. Activation of NF-kappaB by IL-1beta blocks IL-6-induced sustained STAT3 activation and STAT3-dependent gene expression of the human gamma-fibrinogen gene. Cell. Signal. 19: 1866-1878 (2007). *
Albrecht V, Hofer TP, Foxwell B, Frankenberger M, Ziegler-Heitbrock L. Tolerance induced via TLR2 and TLR4 in human dendritic cells: role of IRAK-1. BMC Immunol. 9: 69 (2008). *
Alcaraz A, Hernandez D, Iyu D, Mota R, Ortiz AJ, Atucha NM, Garcia-Estan J, Ortiz MC. Effects of chronic L-NAME on nitrotyrosine expression and renal vascular reactivity in rats with chronic bile duct ligation. Clin. Sci. (Lond.) 115: 57-68 (2008). *
Alcorta DA, Barnes DA, Dooley MA, Sullivan P, Jonas B, Liu Y, Lionaki S, Reddy CB, Chin H, Dempsey AA, Jennette JC, Falk RJ. Leukocyte gene expression signatures in antineutrophil cytoplasmic autoantibody and lupus glomerulonephritis. Kidney Int. 72: 853-864 (2007).
Alcudia JF, Martinez-Gonzalez J, Guadall A, Gonzalez-Diez M, Badimon L, Rodriguez C. Lysyl oxidase and endothelial dysfunction: mechanisms of lysyl oxidase down-regulation by pro-inflammatory cytokines. Front. Biosci. 13: 2721-2727 (2008).
Alderuccio F, Toh BH. Induction of tolerance to self-antigens using genetically modified bone marrow cells. Expert Opin. Biol. Ther. 4: 1007-1014 (2004).
Aldred PM, Hollox EJ, Armour JA. Copy number polymorphism and expression level variation of the human alpha-defensin genes DEFA1 and DEFA3. Hum. Mol. Genet. 14: 2045-2052 (2005). *
Aleffi S, Petrai I, Bertolani C, Parola M, Colombatto S, Novo E, Vizzutti F, Anania FA, Milani S, Rombouts K, Laffi G, Pinzani M, Marra F. Upregulation of proinflammatory and proangiogenic cytokines by leptin in human hepatic stellate cells. Hepatology 42: 1339-1348 (2005). *
Alegre ML, Fallarino F. Mechanisms of CTLA-4-Ig in tolerance induction. Curr. Pharm. Des. 12: 149-160 (2006).
Aleksic T, Baumann B, Wagner M, Adler G, Wirth T, Weber CK. Cellular immune reaction in the pancreas is induced by constitutively active IKK2. Gut 56: 227-236 (2007). *
Aleksunes LM, Manautou JE. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease. Toxicol. Pathol. 35: 459-473 (2007). *
Aleksunes LM, Slitt AL, Maher JM, Dieter MZ, Knight TR, Goedken M, Cherrington NJ, Chan JY, Klaassen CD, Manautou JE. Nuclear factor-E2-related factor 2 expression in liver is critical for induction of NAD(P)H:quinone oxidoreductase 1 during cholestasis. Cell Stress Chaperones 11: 356-363 (2006).
Aleman G, Torres N, Tovar AR. Peroxisome proliferator-activated receptors (PPARs) in obesity and insulin resistance development. Rev. Invest. Clin. 56: 351-367 (2004).
Alemany Bonastre R, Barquinero Manez J, Ramon y Cajal Agueras S. Gene therapy: current situation and expectations. Rev. Clin. Esp. 205: 178-188 (2005).
Alenghat T, Meyers K, Mullican SE, Leitner K, Adeniji-Adele A, Avila J, Bucan M, Ahima RS, Kaestner KH, Lazar MA. Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology. Nature 456: 997-1000 (2008). *
Alenghat T, Yu J, Lazar MA. The N-CoR complex enables chromatin remodeler SNF2H to enhance repression by thyroid hormone receptor. EMBO J. 25: 3966-3974 (2006). *
Alenius GM. Psoriatic arthritis - new insights give new options for treatment. Curr. Med. Chem. 14: 359-366 (2007).
Aleshin S, Grabeklis S, Hanck T, Sergeeva M, Reiser G. PPARgamma positively and PPARalpha negatively control COX-2 expression in rat brain astrocytes through a convergence on PPARbeta/delta via mutual control of PPAR expression levels. Mol. Pharmacol. May 29 [Epub ahead of print] (2009). *
Alex P, Gucek M, Li X. Applications of proteomics in the study of inflammatory bowel diseases: current status and future directions with available technologies. Inflamm. Bowel Dis. 15: 616-629 (2009). *
Alexander D, Friedrich B, Abruzzese T, Gondolph-Zink B, Wulker N, Aicher WK. The active form of leflunomide, HMR1726, facilitates TNF-alpha and IL-17 induced MMP-1 and MMP-3 expression. Cell. Physiol. Biochem. 17: 69-78 (2006). *
Alexander JS, Ando T. Density-dependent control of MAdCAM-1 and chronic inflammation. Focus on "Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells". Am. J. Physiol. Cell Physiol. 288: C243-C244 (2005). *
Alexander K, Edwards C, Misko IS, Geczy AF, Bashir HV, Edmonds JP. The distribution of a specific HLA-B27-associated cell surface component on the tissues of patients with ankylosing spondylitis. Clin. Exp. Immunol. 45: 158-164 (1981). *
Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF. Expression of protooncogene-encoded mRNA by colonic epithelial cells in inflammatory bowel disease. Dig. Dis. Sci. 41: 660-669 (1996).
Alexander RJ, Panja A, Kaplan-Liss E, Mayer L, Raicht RF. Expression of growth factor receptor-encoded mRNA by colonic epithelial cells is altered in inflammatory bowel disease. Dig. Dis. Sci. 40: 485-494 (1995).
Alexander S, Bramson J, Foley R, Xing Z. Protection from endotoxemia by adenoviral-mediated gene transfer of human bactericidal/permeability-increasing protein. Blood 103: 93-99 (2004). *
Alexander WS, Hilton DJ. The role of suppressors of cytokine signaling (SOCS) proteins in regulation of the immune response. Annu. Rev. Immunol. 22: 503-529 (2004). *
Alexis AF, Dudda-Subramanya R, Siu K, Sinha AA. Alopecia areata: genetic complexity underlies clinical heterogeneity. Eur. J. Dermatol. 17: 367-374 (2007).
Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, Peden DB. Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. Ann. Allergy Asthma Immunol. 100: 206-215 (2008).
Alexopoulou L, Kontoyiannis D. Intestinal epithelial barrier and mucosal immunity. Contribution of microbial-associated molecules in innate mucosal responses. Cell. Mol. Life Sci. 62: 1349-1358 (2005). *
Alfalah M, Keiser M, Leeb T, Zimmer KP, Naim HY. Compound heterozygous mutations affect protein folding and function in patients with congenital sucrase-isomaltase deficiency. Gastroenterology 136: 883-892 (2009). *
Alfter K, von Kugelgen I, Haenisch B, Frieling T, Hulsdonk A, Haars U, Rolfs A, Noe G, Kolck UW, Homann J, Molderings GJ. New aspects of liver abnormalities as part of the systemic mast cell activation syndrome. Liver Int. 29: 181-186 (2009). *
Algood HM, Flynn JL. CCR5-deficient mice control Mycobacterium tuberculosis infection despite increased pulmonary lymphocytic infiltration. J. Immunol. 173: 3287-3296 (2004). *
Ali BR. Is cystic fibrosis-related diabetes an apoptotic consequence of ER stress in pancreatic cells? Med. Hypotheses 72: 55-57 (2009).
Ali MS, Pearson JP. Upper airway mucin gene expression: a review. Laryngoscope 117: 932-938 (2007).
Alic M. Is exposure to a patient with Crohn's disease an environmental factor for developing the disease. Gut 45: 631-632 (1999). *
Alimohammadi M, Bjorklund P, Hallgren A, Pontynen N, Szinnai G, Shikama N, Keller MP, Ekwall O, Kinkel SA, Husebye ES, Gustafsson J, Rorsman F, Peltonen L, Betterle C, Perheentupa J, Akerstrom G, Westin G, Scott HS, Hollander GA, Kampe O. Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen. N. Engl. J. Med. 358: 1018-1028 (2008). *
Aliprantis AO, Wang J, Fathman JW, Lemaire R, Dorfman DM, Lafyatis R, Glimcher LH. Transcription factor T-bet regulates skin sclerosis through its function in innate immunity and via IL-13. Proc. Natl. Acad. Sci. U.S.A. 104: 2827-2830 (2007). *
Alirezaei M, Fox HS, Flynn CT, Moore CS, Hebb AL, Frausto RF, Bhan V, Kiosses WB, Whitton JL, Robertson GS, Crocker SJ. Elevated ATG5 expression in autoimmune demyelination and multiple sclerosis. Autophagy 5: 152-158 (2009).
Alkhoury F, Malo MS, Mozumder M, Mostafa G, Hodin RA. Differential regulation of intestinal alkaline phosphatase gene expression by Cdx1 and Cdx2. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G285-G290 (2005). *
Alkim C, Balci M, Alkim H, Dagli U, Parlak E, Tezel A, Ulker A. The importance of peripheral immune cells in inflammatory bowel disease. Turk. J. Gastroenterol. 18: 82-88 (2007). *
Alkim C, Savas B, Ensari A, Alkim H, Dagli U, Parlak E, Ulker A, Sahin B. Expression of p53, VEGF, microvessel density, and cyclin-D1 in noncancerous tissue of inflammatory bowel disease. Dig. Dis. Sci. Nov 26 [Epub ahead of print] (2008). *
Allan SE, Passerini L, Bacchetta R, Crellin N, Dai M, Orban PC, Ziegler SF, Roncarolo MG, Levings MK. The role of 2 FOXP3 isoforms in the generation of human CD4+ Tregs. J. Clin. Invest. 115: 3276-3284 (2005). *
Allayee H, Baylin A, Hartiala J, Wijesuriya H, Mehrabian M, Lusis AJ, Campos H. Nutrigenetic association of the 5-lipoxygenase gene with myocardial infarction. Am. J. Clin. Nutr. 88: 934-940 (2008). *
Allcock R, Dolecki KJ, Boodhoo A, Abdul Khalil A, Wong AM, Price P. Genomic sequence and expression profile of murine Bat1a and Nfkbil1. DNA Seq. 17: 292-299 (2006).
Allcock RJ, Price P, Gaudieri S, Leelayuwat C, Witt CS, Dawkins RL. Characterisation of the human central MHC gene, BAT1: genomic structure and expression. Exp. Clin. Immunogenet. 16: 98-106 (1999).
Allcock RJ, Williams JH, Price P. The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production. Genes Cells 6: 487-494 (2001). *
Allen CE, Richards J, Muthusamy N, Auer H, Liu Y, Robinson ML, Barnard JA, Wu LC. Disruption of ZAS3 in mice alters NF-kappaB and AP-1 DNA binding and T-cell development. Gene Expr. 14: 83-100 (2007).
Aller MA, Arias JL, Garcia-Dominguez J, Arias JI, Duran M, Arias J. Experimental obstructive cholestasis: the wound-like inflammatory liver response. Fibrogenesis Tissue Repair. 1: 6 (2008). *
Allgayer H. Review article: mechanisms of action of mesalazine in preventing colorectal carcinoma in inflammatory bowel disease. Aliment. Pharmacol. Ther. 18 Suppl. 2: 10-14 (2003). *
Allikmets R, Gerrard B, Hutchinson A, Dean M. Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database. Hum. Mol. Genet. 5: 1649-1655 (1996). *
Allison AC. Genetic control of resistance to human malaria. Curr. Opin. Immunol. May 11 [Epub ahead of print] (2009).
Allison MC, Poulter LW. Changes in phenotypically distinct mucosal macrophage populations may be a prerequisite for the development of inflammatory bowel disease. Clin. Exp. Immunol. 85: 504-509 (1991). *
Almada L, Bellarosa C, Giraudi P, Mamprin M, Mediavilla M, Guibert E, Tiribelli C, Rodriguez J. The urea cycle enzymes activity and its gene expression in rat hepatocytes are not affected by cold storage in University of Wisconsin solution. Ann. Hepatol. 4: 224-227 (2005).
Almaguel FG, Liu JW, Pacheco FJ, Casiano CA, De Leon M. Activation and reversal of lipotoxicity in PC12 and rat cortical cells following exposure to palmitic acid. J. Neurosci. Res. 87: 1207-1218 (2009).
Almani M, Raffaeli S, Vider-Shalit T, Tsaban L, Fishbain V, Louzoun Y. Human self-protein CD8(+) T-cell epitopes are both positively and negatively selected. Eur. J. Immunol. 39: 1056-1065 (2009). *
Almendro V, Fuster G, Busquets S, Ametller E, Figueras M, Argiles JM, Lopez-Soriano FJ. Effects of IL-15 on rat brown adipose tissue: uncoupling proteins and PPARs. Obesity (Silver Spring) 16: 285-289 (2008). *
Almirza WH, Dernison MM, Peters PH, van Zoelen EJ, Theuvenet AP. Role of the prostanoid FP receptor in action potential generation and phenotypic transformation of NRK fibroblasts. Cell. Signal. 20: 2022-2029 (2008). *
Alper CA, Marcus-Bagley D, Awdeh Z, Kruskall MS, Eisenbarth GS, Brink SJ, Katz AJ, Stein R, Bing DH, Yunis EJ, Schur PH. Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype. Tissue Antigens 56: 207-216 (2000). *
Alpini G, Glaser SS, Ueno Y, Rodgers R, Phinizy JL, Francis H, Baiocchi L, Holcomb LA, Caligiuri A, LeSage GD. Bile acid feeding induces cholangiocyte proliferation and secretion: evidence for bile acid-regulated ductal secretion. Gastroenterology 116: 179-186 (1999). *
Alrefai WA, Tyagi S, Nazir TM, Barakat J, Anwar SS, Hadjiagapiou C, Bavishi D, Sahi J, Malik P, Goldstein J, Layden TJ, Ramaswamy K, Dudeja PK. Human intestinal anion exchanger isoforms: expression, distribution, and membrane localization. Biochim. Biophys. Acta 1511: 17-27 (2001). *
Altes A, Bach V, Ruiz A, Esteve A, Felez J, Remacha AF, Sarda MP, Baiget M. Mutations in HAMP and HJV genes and their impact on expression of clinical hemochromatosis in a cohort of 100 Spanish patients homozygous for the C282Y mutation of HFE gene. Ann. Hematol. Feb 13 [Epub ahead of print] (2009).
Altucci L, Rossin A, Hirsch O, Nebbioso A, Vitoux D, Wilhelm E, Guidez F, De Simone M, Schiavone EM, Grimwade D, Zelent A, de The H, Gronemeyer H. Rexinoid-triggered differentiation and tumor-selective apoptosis of acute myeloid leukemia by protein kinase a-mediated desubordination of retinoid X receptor. Cancer Res. 65: 8754-8765 (2005). *
Altuwaijri S, Chuang KH, Lai KP, Lai JJ, Lin HY, Young FM, Bottaro A, Tsai MY, Zeng WP, Chang HC, Yeh S, Chang C. Susceptibility to autoimmunity and B cell resistance to apoptosis in mice lacking androgen receptor in B cells. Mol. Endocrinol. 23: 444-453 (2009). *
Aluru M, Xu Y, Guo R, Wang Z, Li S, White W, Wang K, Rodermel S. Generation of transgenic maize with enhanced provitamin A content. J. Exp. Bot. 59: 3551-3562 (2008). *
Alvarado J, Del Castillo JR, Thomas LE. Modulation of membrane type 1 matrix metalloproteinase by LPS and gamma interferon bound to extracellular matrix in intestinal crypt cells. Cytokine 41: 155-161 (2008).
Alvarado J, Taylor P, Castillo JR, Thomas LE. Interferon gamma bound to extracellular matrix changes the hyporesponsiveness to LPS in crypt but not villous intestinal epithelial cells. Immunol. Lett. 99: 109-112 (2005).
Alvarado-Navarro A, Montoya-Buelna M, Munoz-Valle JF, Lopez-Roa RI, Guillen-Vargas C, Fafutis-Morris M. The 3'UTR 1188 A/C polymorphism in the interleukin-12p40 gene (IL-12B) is associated with lepromatous leprosy in the west of Mexico. Immunol. Lett. 118: 148-151 (2008).
Alvarez BV, Kieller DM, Quon AL, Markovich D, Casey JR. Slc26a6: a cardiac chloride-hydroxyl exchanger and predominant chloride-bicarbonate exchanger of the mouse heart. J. Physiol. 561: 721-734 (2004). *
Alvarez D, Arkinson JL, Sun J, Fattouh R, Walker T, Jordana M. Th2 differentiation in distinct lymph nodes influences the site of mucosal Th2 immune-inflammatory responses. J. Immunol. 179: 3287-3296 (2007). *
Alvarez I, Lopez de Castro JA. HLA-B27 and immunogenetics of spondyloarthropathies. Curr. Opin. Rheumatol. 12: 248-253 (2000).
Alvarez JI. Inhibition of Toll-like receptor immune responses by microbial pathogens. Front. Biosci. 10: 582-587 (2005).
Alvarez L, Jara P, Sanchez-Sabate E, Hierro L, Larrauri J, Diaz MC, Camarena C, De La Vega A, Frauca E, Lopez-Collazo E, Lapunzina P. Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1. Hum. Mol. Genet. 13: 2451-2460 (2004). *
Alvarez R, Checa M, Brun S, Vinas O, Mampel T, Iglesias R, Giralt M, Villarroya F. Both retinoic-acid-receptor- and retinoid-X-receptor-dependent signalling pathways mediate the induction of the brown-adipose-tissue-uncoupling-protein-1 gene by retinoids. Biochem. J. 345: 91-97 (2000). *
Alvarez R, de Andres J, Yubero P, Vinas O, Mampel T, Iglesias R, Giralt M, Villarroya F. A novel regulatory pathway of brown fat thermogenesis. Retinoic acid is a transcriptional activator of the mitochondrial uncoupling protein gene. J. Biol. Chem. 270: 5666-5673 (1995). *
Alvarez Y, Tang X, Coligan JE, Borrego F. The CD300a (IRp60) inhibitory receptor is rapidly up-regulated on human neutrophils in response to inflammatory stimuli and modulates CD32a (FcgammaRIIa) mediated signaling. Mol. Immunol. 45: 253-258 (2008). *
Alvarez-Pellitero P. Fish immunity and parasite infections: from innate immunity to immunoprophylactic prospects. Vet. Immunol. Immunopathol. 126: 171-198 (2008).
Alvaro A, Rosales R, Masana L, Vallve JC. Polyunsaturated fatty acids down-regulate in vitro expression of the key intestinal cholesterol absorption protein NPC1L1: no effect of monounsaturated nor saturated fatty acids. J. Nutr. Biochem. May 13 [Epub ahead of print] (2009). *
Alwayn IP, Andersson C, Lee S, Arsenault DA, Bistrian B, Gura KM, Nose V, Zauscher B, Moses MA, Puder M. Inhibition of matrix metalloproteinases increases PPAR-alpha and IL-6 and prevents dietary-induced hepatic steatosis and injury in a murine model. Am. J. Physiol. Gastrointest. Liver Physiol. 291: G1011-G1019 (2006). *
Aly HH, Shimotohno K, Hijikata M. 3D cultured immortalized human hepatocytes useful to develop drugs for blood-borne HCV. Biochem. Biophys. Res. Commun. 379: 330-334 (2009). *
Amador-Noguez D, Dean A, Huang W, Setchell K, Moore D, Darlington G. Alterations in xenobiotic metabolism in the long-lived Little mice. Aging Cell 6: 453-470 (2007). *
Amanatidou V, Sourvinos G, Apostolakis S, Neonaki P, Tsilimigaki A, Krambovitis E, Spandidos DA. RANTES promoter gene polymorphisms and susceptibility to severe respiratory syncytial virus-induced bronchiolitis. Pediatr. Infect. Dis. J. 27: 38-42 (2008).
Amann-Zalcenstein D, Avidan N, Kanyas K, Ebstein RP, Kohn Y, Hamdan A, Ben-Asher E, Karni O, Mujaheed M, Segman RH, Maier W, Macciardi F, Beckmann JS, Lancet D, Lerer B. AHI1, a pivotal neurodevelopmental gene, and C6orf217 are associated with susceptibility to schizophrenia. Eur. J. Hum. Genet. 14: 1111-1119 (2006). *
Amano Y, Cho Y, Matsunawa M, Komiyama K, Makishima M. Increased nuclear expression and transactivation of vitamin D receptor by the cardiotonic steroid bufalin in human myeloid leukemia cells. J. Steroid Biochem. Mol. Biol. 114: 144-151 (2009).
Amaral JD, Castro RE, Sola S, Steer CJ, Rodrigues CM. p53 is a key molecular target of ursodeoxycholic acid in regulating apoptosis. J. Biol. Chem. 282: 34250-34259 (2007). *
Amaral MD, Clarke LA, Ramalho AS, Beck S, Broackes-Carter F, Rowntree R, Mouchel N, Williams SH, Harris A, Tzetis M, Steiner B, Sanz J, Gallati S, Nissim-Rafinifa M, Kerem B, Hefferon T, Cutting GR, Goina E, Pagani F. Quantitative methods for the analysis of CFTR transcripts/splicing variants. J. Cyst. Fibros. 3 Suppl. 2: 17-23 (2004).
Amarapurkar AD, Amarapurkar DN, Vibhav S, Patel ND. Angiogenesis in chronic liver disease. Ann. Hepatol. 6: 170-173 (2007). *
Amarnath S, Dong L, Li J, Wu Y, Chen W. Endogenous TGF-beta activation by reactive oxygen species is key to Foxp3 induction in TCR-stimulated and HIV-1-infected human CD4+CD25- T cells. Retrovirology 4: 57 (2007).
Amasheh S, Barmeyer C, Koch CS, Tavalali S, Mankertz J, Epple HJ, Gehring MM, Florian P, Kroesen AJ, Zeitz M, Fromm M, Schulzke JD. Cytokine-dependent transcriptional down-regulation of epithelial sodium channel in ulcerative colitis. Gastroenterology 126: 1711-1720 (2004). *
Ambati S, Duan J, Choi YH, Hartzell DL, Della-Fera MA, Baile CA. ICV vs. VMH injection of leptin: comparative effects on hypothalamic gene expression. Behav. Brain Res. 196: 279-285 (2009).
Ambrogini E, Toraldo G, Marcocci C. Post-menopausal osteoporosis: is it an autoimmune disease? J. Endocrinol. Invest. 28: S43-S47 (2005).
Ameen C, Edvardsson U, Ljungberg A, Asp L, Akerblad P, Tuneld A, Olofsson SO, Linden D, Oscarsson J. Activation of peroxisome proliferator-activated receptor alpha increases the expression and activity of microsomal triglyceride transfer protein in the liver. J. Biol. Chem. 280: 1224-1229 (2005). *
Ameen N, Alexis J, Salas P. Cellular localization of the cystic fibrosis transmembrane conductance regulator in mouse intestinal tract. Histochem. Cell Biol. 114: 69-75 (2000). *
Amela-Peris R, Aladro Y, Conde-Sendin MA, Alemany-Rodriguez MJ, Munoz-Fernandez C, Reyes-Yanez MP, Deniz-Naranjo MC, Sanchez-Garcia F. Familial multiple sclerosis in Canary Islands. Rev. Neurol. 39: 911-914 (2004).
Amend B, Doster H, Lange C, Dubois E, Kalbacher H, Melms A, Bischof F. Induction of autoimmunity by expansion of autoreactive CD4+CD62Llow cells in vivo. J. Immunol. 177: 4384-4390 (2006). *
Amengual J, Ribot J, Bonet ML, Palou A. Retinoic acid treatment increases lipid oxidation capacity in skeletal muscle of mice. Obesity (Silver Spring) 16: 585-591 (2008). *
Amiel E, Alonso A, Uematsu S, Akira S, Poynter ME, Berwin B. Toll-like receptor regulation of scavenger receptor-A-mediated phagocytosis. J. Leukoc. Biol. 85: 595-605 (2009). *
Amigo L, Castro J, Miquel JF, Zanlungo S, Young SG, Nervi F. Inactivation of hepatic microsomal triglyceride transfer protein protects mice from diet-induced gallstones. Gastroenterology 131: 1870-1878 (2006). *
Amin AR, Patel RN, Thakker GD, Lowenstein CJ, Attur MG, Abramson SB. Post-transcriptional regulation of inducible nitric oxide synthase mRNA in murine macrophages by doxycycline and chemically modified tetracyclines. FEBS Lett. 410: 259-264 (1997).
Amin MR, Malakooti J, Sandoval R, Dudeja PK, Ramaswamy K. IFN-gamma and TNF-alpha regulate the human NHE3 gene expression by modulating the Sp family transcription factors in human intestinal epithelial cell line, C2BBe1. Am. J. Physiol. Cell Physiol. 291: C887-C896 (2006). *
Amit I, Citri A, Shay T, Lu Y, Katz M, Zhang F, Tarcic G, Siwak D, Lahad J, Jacob-Hirsch J, Amariglio N, Vaisman N, Segal E, Rechavi G, Alon U, Mills GB, Domany E, Yarden Y. A module of negative feedback regulators defines growth factor signaling. Nat. Genet. 39: 503-512 (2007). *
Amit-Romach E, Uni Z, Cheled S, Berkovich Z, Reifen R. Bacterial population and innate immunity-related genes in rat gastrointestinal tract are altered by vitamin A-deficient diet. J. Nutr. Biochem. 20: 70-77 (2009). *
Amoli MM, Salway F, Ollier WE, Gonzalez-Gay MA. MCP-1 gene haplotype association in biopsy proven giant cell arteritis. J. Rheumatol. 32: 507-510 (2005).
Amsaguine-Safir S, Bianchi A, Collet P, Huin-Schohn C, Jeanvoine A, Becuwe P, Kremarik-Bouillaud P, Domenjoud L, Keller JM, Schohn H, Dauca M. Induction of the expression of the peroxisome proliferator-activated receptor alpha (PPARalpha) by clofibrate in jerboa tissues. Microsc. Res. Tech. 61: 185-190 (2003). *
Amsen D, Spilianakis CG, Flavell RA. How are T(H)1 and T(H)2 effector cells made? Curr. Opin. Immunol. 21: 153-160 (2009).
An F, Li Q, Tu Z, Bu H, Chan CC, Caspi RR, Lin F. DAF protects against T cell autoreactivity that leads to experimental autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. May 14 [Epub ahead of print] (2009).
An H, Zhao W, Hou J, Zhang Y, Xie Y, Zheng Y, Xu H, Qian C, Zhou J, Yu Y, Liu S, Feng G, Cao X. SHP-2 phosphatase negatively regulates the TRIF adaptor protein-dependent type I interferon and proinflammatory cytokine production. Immunity 25: 919-928 (2006). *
An P, Thio CL, Kirk GD, Donfield S, Goedert JJ, Winkler CA. Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance. J. Infect. Dis. 198: 1159-1165 (2008). *
Anakk S, Huang W, Staudinger JL, Tan K, Cole TJ, Moore DD, Strobel HW. Gender dictates the nuclear receptor mediated regulation of CYP3A44. Drug Metab. Dispos. 35: 36-42 (2007). *
Anakk S, Kalsotra A, Kikuta Y, Huang W, Zhang J, Staudinger JL, Moore DD, Strobel HW. CAR/PXR provide directives for Cyp3a41 gene regulation differently from Cyp3a11. Pharmacogenomics J. 4: 91-101 (2004). *
Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors. FASEB J. 17: 1736-1738 (2003). *
Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J. Biol. Chem. 276: 28857-28865 (2001). *
Anapolsky A, Teng S, Dixit S, Piquette-Miller M. The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and metabolizing enzymes in mice. Drug Metab. Dispos. 34: 405-409 (2006). *
Anchang B, Sadeh MJ, Jacob J, Tresch A, Vlad MO, Oefner PJ, Spang R. Special feature: modeling the temporal interplay of molecular signaling and gene expression by using dynamic nested effects models. Proc. Natl. Acad. Sci. U.S.A. 106: 6447-6452 (2009). *
Andersen J, Vanscoy S, Cheng TF, Gomez D, Reich NC. IRF-3-dependent and augmented target genes during viral infection. Genes Immun. 9: 168-175 (2008). *
Andersen MH, Schrama D, Thor Straten P, Becker JC. Cytotoxic T cells. J. Invest. Dermatol. 126: 32-41 (2006). *
Anderson GG, Moreau-Marquis S, Stanton BA, O'Toole GA. In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells. Infect. Immun. 76: 1423-1433 (2008). *
Anderson GJ, Frazer DM, McLaren GD. Iron absorption and metabolism. Curr. Opin. Gastroenterol. 25: 129-135 (2009).
Anderson JP, Mueller JL, Rosengren S, Boyle DL, Schaner P, Cannon SB, Goodyear CS, Hoffman HM. Structural, expression, and evolutionary analysis of mouse CIAS1. Gene 338: 25-34 (2004). *
Anderson MK. At the crossroads: diverse roles of early thymocyte transcriptional regulators. Immunol. Rev. 209: 191-211 (2006).
Anderson MS, Venanzi ES, Chen Z, Berzins SP, Benoist C, Mathis D. The cellular mechanism of Aire control of T cell tolerance. Immunity 23: 227-239 (2005). *
Anderson MS, Venanzi ES, Klein L, Chen Z, Berzins SP, Turley SJ, von Boehmer H, Bronson R, Dierich A, Benoist C, Mathis D. Projection of an immunological self shadow within the thymus by the aire protein. Science 298: 1395-1401 (2002). *
Anderson SK, Dewar K, Goulet ML, Leveque G, Makrigiannis AP. Complete elucidation of a minimal class I MHC natural killer cell receptor haplotype. Genes Immun. 6: 481-492 (2005). *
Anderson SP, Dunn C, Laughter A, Yoon L, Swanson C, Stulnig TM, Steffensen KR, Chandraratna RA, Gustafsson JA, Corton JC. Overlapping transcriptional programs regulated by the nuclear receptors peroxisome proliferator-activated receptor alpha, retinoid X receptor and liver X receptor in mouse liver. Mol. Pharmacol. 66: 1440-1452 (2004). *
Anderson SP, Dunn CS, Cattley RC, Corton JC. Hepatocellular proliferation in response to a peroxisome proliferator does not require TNFalpha signaling. Carcinogenesis 22: 1843-1851 (2001). *
Anderson SP, Howroyd P, Liu J, Qian X, Bahnemann R, Swanson C, Kwak MK, Kensler TW, Corton JC. The transcriptional response to a peroxisome proliferator-activated receptor alpha agonist includes increased expression of proteome maintenance genes. J. Biol. Chem. 279: 52390-52398 (2004). *
Anderson SP, Yoon L, Richard EB, Dunn CS, Cattley RC, Corton JC. Delayed liver regeneration in peroxisome proliferator-activated receptor-alpha-null mice. Hepatology 36: 544-554 (2002). *
Andersson D, Kotarsky K, Wu J, Agace W, Duan RD. Expression of alkaline sphingomyelinase in yeast cells and anti-inflammatory effects of the expressed enzyme in a rat colitis model. Dig. Dis. Sci. Nov 7 [Epub ahead of print] (2008). *
Andersson HA, Passeri MF, Barry MA. Rad23 as a reciprocal agent for stimulating or repressing immune responses. Hum. Gene Ther. 16: 634-641 (2005).
Andersson J, Tran DQ, Pesu M, Davidson TS, Ramsey H, O'Shea JJ, Shevach EM. CD4+FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner. J. Exp. Med. 205: 1975-1981 (2008). *
Andersson U, Tracey KJ. HMGB1 in sepsis. Scand. J. Infect. Dis. 35: 577-584 (2003).
Ando H, Tsuruoka S, Yamamoto H, Takamura T, Kaneko S, Fujimura A. Effects of pravastatin on the expression of ATP-binding cassette transporter A1. J. Pharmacol. Exp. Ther. 311: 420-425 (2004). *
Ando T, Nobata K, Watanabe O, Ina K, Kusugami K, Maeda O, Ishiguro K, Ohmiya N, Niwa Y, Goto H. Abnormalities in the upper gastrointestinal tract in inflammatory bowel disease. Inflammopharmacology Apr 28 [Epub ahead of print] (2007).
Ando T, Watanabe O, Ishiguro K, Maeda O, Ishikawa D, Minami M, Hasegawa M, Kondo S, Goto Y, Ohmiya N, Niwa Y, Goto H. Relationships between Helicobacter pylori infection status, endoscopic, histopathological findings, and cytokine production in the duodenum of Crohn's disease patients. J. Gastroenterol. Hepatol. 23 Suppl. 2: S193-S197 (2008).
Andoh A, Fujino S, Bamba S, Araki Y, Okuno T, Bamba T, Fujiyama Y. IL-17 selectively down-regulates TNF-alpha-induced RANTES gene expression in human colonic subepithelial myofibroblasts. J. Immunol. 169: 1683-1687 (2002). *
Andoh A, Fujino S, Hirai Y, Fujiyama Y. Epimorphin expression in human colonic myofibroblasts. Int. J. Mol. Med. 13: 57-61 (2004).
Andoh A, Shioya M, Nishida A, Bamba S, Tsujikawa T, Kim-Mitsuyama S, Fujiyama Y. Expression of IL-24, an activator of the JAK1/STAT3/SOCS3 cascade, is enhanced in inflammatory bowel disease. J. Immunol. Jun 17 [Epub ahead of print] (2009).
Andrade RJ, Lucena MI, Alonso A, Garcia-Cores M, Garcia-Ruiz E, Benitez R, Fernandez MC, Pelaez G, Romero M, Corpas R, Duran JA, Jimenez M, Rodrigo L, Nogueras F, Martin-Vivaldi R, Navarro JM, Salmeron J, de la Cuesta FS, Hidalgo R. HLA class II genotype influences the type of liver injury in drug-induced idiosyncratic liver disease. Hepatology 39: 1603-1612 (2004). *
Andrassy M, Igwe J, Autschbach F, Volz C, Remppis A, Neurath MF, Schleicher E, Humpert PM, Wendt T, Liliensiek B, Morcos M, Schiekofer S, Thiele K, Chen J, Kientsch-Engel R, Schmidt AM, Stremmel W, Stern DM, Katus HA, Nawroth PP, Bierhaus A. Posttranslationally modified proteins as mediators of sustained intestinal inflammation. Am. J. Pathol. 169: 1223-1237 (2006). *
Andrault JB, Gaillard I, Giorgi D, Rouquier S. Expansion of the BPI family by duplication on human chromosome 20: characterization of the RY gene cluster in 20q11.21 encoding olfactory transporters/antimicrobial-like peptides. Genomics 82: 172-184 (2003). *
Andre J, Cimaz R, Ranchin B, Galambrun C, Bertrand Y, Bouvier R, Rieux-Laucat F, Trescol-Biemont MC, Cochat P, Bonnefoy-Berard N. Overexpression of the antiapoptotic gene Bfl-1 in B cells from patients with familial systemic lupus erythematosus. Lupus 16: 95-100 (2007).
Andre MF, Aumaitre O, Piette JC, Grateau G, Cardoso MC, Ouchchane L, Kemeny JL, Dastugue B, Delpech M, Creveaux I. Analysis of the NOD2/CARD15 gene in patients affected with the aseptic abscesses syndrome with or without inflammatory bowel disease. Dig. Dis. Sci. 53: 490-499 (2008). *
Andreakos E, Foxwell B, Feldmann M. Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation? Immunol. Rev. 202: 250-265 (2004). *
Andreakos E, Sacre S, Foxwell BM, Feldmann M. The Toll-like receptor-nuclear factor kappaB pathway in rheumatoid arthritis. Front. Biosci. 10: 2478-2488 (2005).
Andreas K, Haupl T, Lubke C, Ringe J, Morawietz L, Wachtel A, Sittinger M, Kaps C. Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis Res. Ther. 11: R15 (2009). *
Andreas K, Luebke C, Haeupl T, Dehne T, Morawietz L, Ringe J, Kaps C, Sittinger M. Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study. Arthritis Res. Ther. 10: R9 (2008). *
Andreeva-Gateva P. Peroxisome proliferator activated receptors PPARs: their role in carbohydrate and lipid metabolism. Ann. Biol. Clin. (Paris) 61: 295-303 (2003).
Andrejko KM, Raj NR, Kim PK, Cereda M, Deutschman CS. IL-6 modulates sepsis-induced decreases in transcription of hepatic organic anion and bile acid transporters. Shock 29: 490-496 (2008).
Andres D, Bautista M, Cascales M. Attenuation of cyclosporine A toxicity by sublethal heat shock. Role of catalase. Biochem. Pharmacol. 69: 493-501 (2005). *
Andres PG, Beck PL, Mizoguchi E, Mizoguchi A, Bhan AK, Dawson T, Kuziel WA, Maeda N, MacDermott RP, Podolsky DK, Reinecker HC. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. J. Immunol. 164: 6303-6312 (2000). *
Andresen L, Jorgensen VL, Perner A, Hansen A, Eugen-Olsen J, Rask-Madsen J. Activation of nuclear factor kappaB in colonic mucosa from patients with collagenous and ulcerative colitis. Gut 54: 503-509 (2005). *
Andriopoulos Jr B, Corradini E, Xia Y, Faasse SA, Chen S, Grgurevic L, Knutson MD, Pietrangelo A, Vukicevic S, Lin HY, Babitt JL. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat. Genet. 41: 482-487 (2009). *
Andrulionyte L, Peltola P, Chiasson JL, Laakso M. Single nucleotide polymorphisms of PPARD in combination with the Gly482Ser substitution of PGC-1A and the Pro12Ala substitution of PPARG2 predict the conversion from impaired glucose tolerance to type 2 diabetes: the STOP-NIDDM trial. Diabetes 55: 2148-2152 (2006). *
Aneja RK, Tsung A, Sjodin H, Gefter JV, Delude RL, Billiar TR, Fink MP. Preconditioning with high mobility group box 1 (HMGB1) induces lipopolysaccharide (LPS) tolerance. J. Leukoc. Biol. 84: 1326-1334 (2008). *
Anest V, Hanson JL, Cogswell PC, Steinbrecher KA, Strahl BD, Baldwin AS. A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression. Nature 423: 659-663 (2003). *
Anetor JI, Ajose F, Anetor GO, Iyanda AA, Babalola OO, Adeniyi FA. High cadmium/zinc ratio in cigarette smokers:potential implications as a biomarker of risk of prostate cancer. Niger J. Physiol. Sci. 23: 41-49 (2008).
Anezaki Y, Ohshima S, Ishii H, Kinoshita N, Dohmen T, Kataoka E, Sato W, Iizuka M, Goto T, Sasaki J, Sasaki T, Suzuki A, Ohnishi H, Horie Y. Sex difference in the liver of hepatocyte-specific Pten-deficient mice: a model of nonalcoholic steatohepatitis. Hepatol. Res. 39: 609-618 (2009).
Ang DK, Brodnicki TC, Jordan MA, Wilson WE, Silveira P, Gliddon BL, Baxter AG, van Driel IR. Two genetic loci independently confer susceptibility to autoimmune gastritis. Int. Immunol. 19: 1135-1144 (2007). *
Angelo G, Lamon-Fava S, Sonna LA, Lindauer ML, Wood RJ. Heat shock protein 90beta: a novel mediator of vitamin D action. Biochem. Biophys. Res. Commun. 367: 578-583 (2008). *
Anger T, Ekici AB, Daniel WG, Garlichs CD. Gene polymorphisms leading to calcified and stenotic aortic valves. Herz. 31: 635-643 (2006).
Angers I, Sancho-Shimizu V, Descoteaux A, Gewirtz AT, Malo D. Tlr5 is not primarily associated with susceptibility to Salmonella typhimurium infection in MOLF/Ei mice. Mamm. Genome 17: 385-397 (2006). *
Anghel SI, Wahli W. Fat poetry: a kingdom for PPARgamma. Cell Res. 17: 486-511 (2007). *
Anglicheau D, Thervet E, Etienne I, Hurault De Ligny B, Le Meur Y, Touchard G, Buchler M, Laurent-Puig P, Tregouet D, Beaune P, Daly A, Legendre C, Marquet P. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation. Clin. Pharmacol. Ther. 75: 422-433 (2004). *
Anheim M, Degos B, Echaniz-Laguna A, Fleury M, Grucker M, Tranchant C. Ataxia associated with gluten sensitivity, myth or reality? Rev. Neurol. (Paris) 162: 214-221 (2006).
Anilkumar N, Weber R, Zhang M, Brewer A, Shah AM. Nox4 and Nox2 NADPH oxidases mediate distinct cellular redox signaling responses to agonist stimulation. Arterioscler. Thromb. Vasc. Biol. 28: 1347-1354 (2008).
Anjos S, Polychronakos C. Mechanisms of genetic susceptibility to type I diabetes: beyond HLA. Mol. Genet. Metab. 81: 187-195 (2004). *
Anjos SM, Tessier MC, Polychronakos C. Association of the cytotoxic T lymphocyte-associated antigen 4 gene with type 1 diabetes: evidence for independent effects of two polymorphisms on the same haplotype block. J. Clin. Endocrinol. Metab. 89: 6257-6265 (2004). *
Annereau JP, Szakacs G, Tucker CJ, Arciello A, Cardarelli C, Collins J, Grissom S, Zeeberg B, Reinhold W, Weinstein J, Pommier Y, Paules RS, Gottesman MM. Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance. Mol. Pharmacol. 66: 1397-1405 (2004). *
Annese V, Valvano MR, Palmieri O, Latiano A, Bossa F, Andriulli A. Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis. World J. Gastroenterol. 12: 3636-3644 (2006). *
Annibali V, Giovanni SD, Cannoni S, Giugni E, Bomprezzi R, Mattei C, Elkahloun A, Coccia EM, Alfo M, Orzi F, Ristori G, Salvetti M. Gene expression profiles reveal homeostatic dynamics during interferon-beta therapy in multiple sclerosis. Autoimmunity 40: 16-22 (2007).
Annilo T, Chen ZQ, Shulenin S, Dean M. Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes. Mamm. Genome 14: 7-20 (2003). *
Annilo T, Dean M. Degeneration of an ATP-binding cassette transporter gene, ABCC13, in different mammalian lineages. Genomics 84: 34-46 (2004). *
Annilo T, Tammur J, Hutchinson A, Rzhetsky A, Dean M, Allikmets R. Human and mouse orthologs of a new ATP-binding cassette gene, ABCG4. Cytogenet. Cell. Genet. 94: 196-201 (2001).
Annoni A, Battaglia M, Follenzi A, Lombardo A, Sergi-Sergi L, Naldini L, Roncarolo MG. The immune response to lentiviral-delivered transgene is modulated in vivo by transgene expressing antigen presenting cells but not by CD4+CD25+ regulatory T cells. Blood 110: 1788-1796 (2007). *
Annunziato F, Cosmi L, Santarlasci V, Maggi L, Liotta F, Mazzinghi B, Parente E, Fil� L, Ferri S, Frosali F, Giudici F, Romagnani P, Parronchi P, Tonelli F, Maggi E, Romagnani S. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 204: 1849-1861 (2007). *
Anolik JH. B cell biology and dysfunction in SLE. Bull. N.Y.U. Hosp. Jt. Dis. 65: 182-186 (2007). *
Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu. Rev. Immunol. 24: 607-656 (2006). *
Anson DS, Smith GJ, Parsons DW. Gene therapy for cystic fibrosis airway disease- is clinical success imminent? Curr. Gene Ther. 6: 161-179 (2006).
Anstee QM, Wright M, Goldin R, Thursz MR. Parenchymal extinction: coagulation and hepatic fibrogenesis. Clin. Liver Dis. 13: 117-126 (2009).
Antes TJ, Levy-Wilson B. HNF-3 beta, C/EBP beta, and HNF-4 act in synergy to enhance transcription of the human apolipoprotein B gene in intestinal cells. DNA Cell Biol. 20: 67-74 (2001).
Anthoni C, Laukoetter MG, Rijcken E, Vowinkel T, Mennigen R, Muller S, Senninger N, Russell J, Jauch J, Bergmann J, Granger DN, Krieglstein CF. Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1131-G1137 (2006). *
Anthoni H, Zucchelli M, Matsson H, Muller-Myhsok B, Fransson I, Schumacher J, Massinen S, Onkamo P, Warnke A, Griesemann H, Hoffmann P, Nopola-Hemmi J, Lyytinen H, Schulte-Korne G, Kere J, Nothen MM, Peyrard-Janvid M. A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia. Hum. Mol. Genet. 16: 667-677 (2007). *
Antille C, Frei M, Sorg O, Tran C, Kaya G, Masouye I, Fontao L, Prins C, Saurat JH. Amicrobial pustulosis of the folds associated with auto-immune disorders. A case report with an analysis of cytokine expression profile in skin lesions of cutaneous neutrophilic lupus. Dermatology 216: 324-329 (2008).
Antoniazi S, Price HP, Kropf P, Freudenberg MA, Galanos C, Smith DF, Muller I. Chemokine gene expression in Toll-like receptor-competent and -deficient mice infected with Leishmania major. Infect. Immun. 72: 5168-5174 (2004). *
Antonicelli R, Olivieri F, Cavallone L, Spazzafumo L, Bonafe M, Marchegiani F, Cardelli M, Galeazzi R, Giovagnetti S, Perna GP, Franceschi C. Tumor necrosis factor-alpha gene -308G>A polymorphism is associated with ST-elevation myocardial infarction and with high plasma levels of biochemical ischemia markers. Coron. Artery Dis. 16: 489-493 (2005).
Antonioli L, Fornai M, Colucci R, Ghisu N, Tuccori M, Del Tacca M, Blandizzi C. Pharmacological modulation of adenosine system: novel options for treatment of inflammatory bowel diseases. Inflamm. Bowel Dis. 14: 566-574 (2008). *
Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP. Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology 136: 2325-2333 (2009). *
Antoniv TT, Ivashkiv LB. Dysregulation of interleukin-10-dependent gene expression in rheumatoid arthritis synovial macrophages. Arthritis Rheum. 54: 2711-2721 (2006). *
Antonson P, Jakobsson T, Alml�f T, Guldevall K, Steffensen KR, Gustafsson JA. RAP250 is a coactivator in the transforming growth factor beta signaling pathway that interacts with SMAD2 and SMAD3. J. Biol. Chem. 283: 8995-9001 (2008). *
Antony JM, Ellestad KK, Hammond R, Imaizumi K, Mallet F, Warren KG, Power C. The human endogenous retrovirus envelope glycoprotein, syncytin-1, regulates neuroinflammation and its receptor expression in multiple sclerosis: a role for endoplasmic reticulum chaperones in astrocytes. J. Immunol. 179: 1210-1224 (2007). *
Antony JM, Izad M, Bar-Or A, Warren KG, Vodjgani M, Mallet F, Power C. Quantitative analysis of human endogenous retrovirus-W env in neuroinflammatory diseases. AIDS Res. Hum. Retroviruses 22: 1253-1259 (2006).
Antony JM, Zhu Y, Izad M, Warren KG, Vodjgani M, Mallet F, Power C. Comparative expression of human endogenous retrovirus-W genes in multiple sclerosis. AIDS Res. Hum. Retroviruses 23: 1251-1256 (2007).
Antonyak MA, Li B, Regan AD, Feng Q, Dusaban SS, Cerione RA. Tissue transglutaminase is an essential participant in the EGF-stimulated signaling pathway leading to cancer cell migration and invasion. J. Biol. Chem. Apr 29 [Epub ahead of print] (2009). *
Antoun J, Amet Y, Simon B, Dreano Y, Corlu A, Corcos L, Salaun JP, Plee-Gautier E. CYP4A11 is repressed by retinoic acid in human liver cells. FEBS Lett. 580: 3361-3367 (2006). *
Antoun J, Goulitquer S, Amet Y, Dreano Y, Salaun JP, Corcos L, Plee-Gautier E. CYP4F3B is induced by PGA1 in human liver cells: a regulation of the 20-HETE synthesis. J. Lipid Res. 49: 2135-2141 (2008). *
Anuchapreeda S, Thanarattanakorn P, Sittipreechacharn S, Tima S, Chanarat P, Limtrakul P. Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells. Arch. Pharm. Res. 29: 866-873 (2006).
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T, Yamanaka S. Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321: 699-702 (2008). *
Aoki CA, Dawson K, Kenny TP, Gershwin ME, Bowlus CL. Gene expression by PBMC in primary sclerosing cholangitis: evidence for dysregulation of immune mediated genes. Clin. Dev. Immunol. 13: 265-271 (2006). *
Aoki T. Genetic disorders of copper transport - diagnosis and new treatment for the patients of Wilson's disease. No To Hattatsu 37: 99-109 (2005).
Aouabdi S, Gibson GG, Plant N. Transcriptional regulation of the PXR gene: identification and characterization of a functional PPARalpha-binding site within the proximal promoter of the PXR gene. Drug Metab. Dispos. 34: 138-144 (2006). *
Aouacheria A, Navratil V, Lopez-Perez R, Gutierrez NC, Churkin A, Barash D, Mouchiroud D, Gautier C. In silico whole-genome screening for cancer-related single-nucleotide polymorphisms located in human mRNA untranslated regions. BMC Genomics 8: 2 (2007). *
Aouadi M, Tesz GJ, Nicoloro SM, Wang M, Chouinard M, Soto E, Ostroff GR, Czech MP. Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature 458: 1180-1184 (2009). *
Aoudjit F, Brochu N, Morin N, Poulin G, Stratowa C, Audette M. Heterodimeric retinoic acid receptor-beta and retinoid X receptor-alpha complexes stimulate expression of the intercellular adhesion molecule-1 gene. Cell Growth Differ. 6: 515-521 (1995).
Aoyama T, Ikejima K, Kon K, Okumura K, Arai K, Watanabe S. Pioglitazone promotes survival and prevents hepatic regeneration failure after partial hepatectomy in obese and diabetic KK-Ay mice. Hepatology 49: 1636-1644 (2009).
Aoyama T, Peters JM, Iritani N, Nakajima T, Furihata K, Hashimoto T, Gonzalez FJ. Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor alpha (PPARalpha). J. Biol. Chem. 273: 5678-5684 (1998). *
Apoil PA, Kuhlein E, Robert A, Rubie H, Blancher A. HIGM syndrome caused by insertion of an AluYb8 element in exon 1 of the CD40LG gene. Immunogenetics 59: 17-23 (2007). *
Apostolaki M, Manoloukos M, Roulis M, Wurbel MA, Muller W, Papadakis KA, Kontoyiannis DL, Malissen B, Kollias G. Role of beta7 integrin and the chemokine/chemokine receptor pair CCL25/CCR9 in modeled TNF-dependent Crohn's disease. Gastroenterology 134: 2025-2035 (2008). *
Appledorn DM, Patial S, McBride A, Godbehere S, Van Rooijen N, Parameswaran N, Amalfitano A. Adenovirus vector-induced innate inflammatory mediators, MAPK signaling, as well as adaptive immune responses are dependent upon both TLR2 and TLR9 in vivo. J. Immunol. 181: 2134-2144 (2008).
Apps R, Murphy SP, Fernando R, Gardner L, Ahad T, Moffett A. Human leucocyte antigen (HLA) expression of primary trophoblast cells and placental cell lines, determined using single antigen beads to characterize allotype specificities of anti-HLA antibodies. Immunology 127: 26-39 (2009). *
Apte UM, Banerjee A, McRee R, Wellberg E, Ramaiah SK. Role of osteopontin in hepatic neutrophil infiltration during alcoholic steatohepatitis. Toxicol. Appl. Pharmacol. 207: 25-38 (2005). *
Aptsiauri N, Carretero R, Garcia-Lora A, Real LM, Cabrera T, Garrido F. Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations. Cancer Immunol. Immunother. 57: 1727-1733 (2008).
Aquino JB, Marmigere F, Lallemend F, Lundgren TK, Villar MJ, Wegner M, Ernfors P. Differential expression and dynamic changes of murine NEDD9 in progenitor cells of diverse tissues. Gene Expr. Patterns 8: 217-226 (2008).
Ara AI, Xia M, Ramani K, Mato JM, Lu SC. S-Adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. Hepatology 47: 1655-1666 (2008). *
Arabzadeh A, Troy TC, Turksen K. Changes in the distribution pattern of claudin tight junction proteins during the progression of mouse skin tumorigenesis. BMC Cancer 7: 196 (2007). *
Arachchige PG, Takahashi Y, Ide T. Dietary sesamin and docosahexaenoic and eicosapentaenoic acids synergistically increase the gene expression of enzymes involved in hepatic peroxisomal fatty acid oxidation in rats. Metabolism 55: 381-390 (2006). *
Arad G, Hillman D, Levy R, Kaempfer R. Superantigen antagonist blocks Th1 cytokine gene induction and lethal shock. J. Leukoc. Biol. 69: 921-927 (2001). *
Arafat HA, Lada E, Katakam AK, Amin N. Osteopontin deficiency impacts the pancreatic TH1/TH2 cytokine profile following multiple low dose streptozotocin-induced diabetes. Exp. Clin. Endocrinol. Diabetes 114: 555-562 (2006).
Arai T, Kaneko H, Ohnishi H, Matsui E, Fukao T, Kawamoto N, Kasahara K, Kondo N. Hypothermia augments NF-kappaB activity and the production of IL-12 and IFN-gamma. Allergol. Int. 57: 331-338 (2008).
Araki M, Nozaki Y, Motojima K. Transcriptional regulation of metabolic switching PDK4 gene under various physiological conditions. Yakugaku Zasshi 127: 153-162 (2007).
Araki Y, Wang Z, Zang C, Wood WH 3rd, Schones D, Cui K, Roh TY, Lhotsky B, Wersto RP, Peng W, Becker KG, Zhao K, Weng NP. Genome-wide analysis of histone methylation reveals chromatin state-based regulation of gene transcription and function of memory CD8(+) T cells. Immunity Jun 10 [Epub ahead of print] (2009).
Arakura F, Hida S, Ichikawa E, Yajima C, Nakajima S, Saida T, Taki S. Genetic control directed toward spontaneous IFN-alpha/IFN-beta responses and downstream IFN-gamma expression influences the pathogenesis of a murine psoriasis-like skin disease. J. Immunol. 179: 3249-3257 (2007). *
Aranami T, Yamamura T. Th17 cells and autoimmune encephalomyelitis (EAE/MS). Allergol. Int. 57: 115-120 (2008). *
Arancibia SA, Beltran CJ, Aguirre IM, Silva P, Peralta AL, Malinarich F, Hermoso MA. Toll-like receptors are key participants in innate immune responses. Biol. Res. 40: 97-112 (2007). *
Aranda A, Pascual A. Nuclear hormone receptors and gene expression. Physiol. Rev. 81: 1269-1304 (2001). *
Aranda V, Martinez I, Melero S, Lecanda J, Banales JM, Prieto J, Medina JF. Shared apical sorting of anion exchanger isoforms AE2a, AE2b1, and AE2b2 in primary hepatocytes. Biochem. Biophys. Res. Commun. 319: 1040-1046 (2004). *
Aranyi T, Ratajewski M, Bardoczy V, Pulaski L, Bors A, Tordai A, Varadi A. Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6. J. Biol. Chem. 280: 18643-18550 (2005). *
Aravalli RN, Hu S, Lokensgard JR. Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia. J. Neuroinflammation 4: 11 (2007).
Aravindhan K, Webb CL, Jaye M, Ghosh A, Willette RN, Dinardo NJ, Jucker BM. Assessing the effects of LXR agonists on cellular cholesterol handling: a stable isotope tracer study. J. Lipid Res. 47: 1250-1260 (2006). *
Archer A, Lauter G, Hauptmann G, Mode A, Gustafsson JA. Transcriptional activity and developmental expression of liver X receptor (lxr) in zebrafish. Dev. Dyn. 237: 1090-1098 (2008).
Archer H, Jura N, Keller J, Jacobson M, Bar-Sagi D. A mouse model of hereditary pancreatitis generated by transgenic expression of R122H trypsinogen. Gastroenterology 131: 1844-1855 (2006). *
Arcos-Burgos M, Palacio LG, Mora O, Sanchez JL, Jimenez M, Jimenez I. Molecular genetic aspects of the susceptibility to develop idiopathic epilepsy. Rev. Neurol. 30: 173-177 (2000).
Ardeniz O, Avci CB, Sin A, Ozgen G, Gunsar F, Mete N, Gulbahar O, Kokuludag A. Vitamin D deficiency in the absence of enteropathy in three cases with common variable immunodeficiency. Int. Arch. Allergy Immunol. 147: 74-83 (2008).
Ardern-Jones MR, Black AP, Bateman EA, Ogg GS. Bacterial superantigen facilitates epithelial presentation of allergen to T helper 2 cells. Proc. Natl. Acad. Sci. U.S.A. 104: 5557-5562 (2007). *
Ardizzone S, Maconi G, Bianchi V, Russo A, Colombo E, Cassinotti A, Penati C, Tenchini ML, Bianchi Porro G. Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease. Inflamm. Bowel Dis. 13: 516-523 (2007). *
Arellanes-Garcia L, Bautista N, Mora P, Ortega-Larrocea G, Burguet A, Gorodezky C. HLA-DR is strongly associated with Vogt-Koyanagi-Harada disease in Mexican Mestizo patients. Ocul. Immunol. Inflamm. 6: 93-100 (1998).
Arenas F, Hervias I, Uriz M, Joplin R, Prieto J, Medina JF. Combination of ursodeoxycholic acid and glucocorticoids upregulates the AE2 alternate promoter in human liver cells. J. Clin. Invest. 118: 695-709 (2008). *
Arentz-Hansen EH, McAdam SN, Molberg O, Kristiansen C, Sollid LM. Production of a panel of recombinant gliadins for the characterisation of T cell reactivity in coeliac disease. Gut 46: 46-51 (2000). *
Argent RH, Kidd M, Owen RJ, Thomas RJ, Limb MC, Atherton JC. Determinants and consequences of different levels of CagA phosphorylation for clinical isolates of Helicobacter pylori. Gastroenterology 127: 514-523 (2004). *
Argyropoulos C, Nikiforidis GC, Theodoropoulou M, Adamopoulos P, Boubali S, Georgakopoulos TN, Paliogianni F, Papavassiliou AG, Mouzaki A. Mining microarray data to identify transcription factors expressed in naive resting but not activated T lymphocytes. Genes Immun. 5: 16-25 (2004). *
Aricha R, Feferman T, Fuchs S, Souroujon MC. Ex vivo generated regulatory T cells modulate experimental autoimmune myasthenia gravis. J. Immunol. 180: 2132-2139 (2008). *
Arikan C, Berdeli A, Ozgenc F, Tumgor G, Yagci RV, Aydogdu S. Positive association of macrophage migration inhibitory factor gene-173G/C polymorphism with biliary atresia. J. Pediatr. Gastroenterol. Nutr. 42: 77-82 (2006). *
Arimilli S, Johnson JB, Clark KM, Graff AH, Alexander-Miller MA, Mizel SB, Parks GD. Engineered expression of the TLR5 ligand flagellin enhances paramyxovirus activation of human dendritic cell function. J. Virol. 82: 10975-10985 (2008). *
Arimoto K, Kadowaki N, Ishikawa T, Ichinohe T, Uchiyama T. FOXP3 expression in peripheral blood rapidly recovers and lacks correlation with the occurrence of graft-versus-host disease after allogeneic stem cell transplantation. Int. J. Hematol. 85: 154-162 (2007).
Arimura S, Matsunaga A, Kitamura T, Aoki K, Aoki M, Taketo MM. Reduced level of smoothened suppresses intestinal tumorigenesis by down-regulation of Wnt signaling. Gastroenterology May 6 [Epub ahead of print] (2009). *
Arina A, Murillo O, Dubrot J, Azpilikueta A, Alfaro C, Perez-Gracia JL, Bendandi M, Palencia B, Hervas-Stubbs S, Melero I. Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer. Expert Opin. Biol. Ther. 7: 599-615 (2007).
Arisawa S, Ishida K, Kameyama N, Ueyama J, Hattori A, Tatsumi Y, Hayashi H, Yano M, Hayashi K, Katano Y, Gotoh H, Takagi K, Wakusawa S. Ursodeoxycholic acid induces glutathione synthesis through activation of PI3K/Akt pathway in HepG2 cells. Biochem. Pharmacol. 77: 858-866 (2009). *
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Hasegawa S, Takagi T, Wang FY, Hirata I, Nakano H. The relationship between Helicobacter pylori infection and promoter polymorphism of the Nrf2 gene in chronic gastritis. Int. J. Mol. Med. 19: 143-148 (2007). *
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Arima Y, Okubo M, Hirata I, Nakano H. The influence of promoter polymorphism of nuclear factor-erythroid 2-related factor 2 gene on the aberrant DNA methylation in gastric epithelium. Oncol. Rep. 19: 211-216 (2008). *
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Okubo M, Hirata I, Nakano H. Nrf2 gene promoter polymorphism and gastric carcinogenesis. Hepatogastroenterology 55: 750-754 (2008).
Arisawa T, Tahara T, Shibata T, Nagasaka M, Nakamura M, Kamiya Y, Fujita H, Yoshioka D, Okubo M, Sakata M, Wang FY, Hirata I, Nakano H. Nrf2 gene promoter polymorphism is associated with ulcerative colitis in a Japanese population. Hepatogastroenterology 55: 394-397 (2008).
Arita M, Clish CB, Serhan CN. The contributions of aspirin and microbial oxygenase to the biosynthesis of anti-inflammatory resolvins: novel oxygenase products from omega-3 polyunsaturated fatty acids. Biochem. Biophys. Res. Commun. 338: 149-157 (2005). *
Arita M, Yoshida M, Hong S, Tjonahen E, Glickman JN, Petasis NA, Blumberg RS, Serhan CN. Resolvin E1, an endogenous lipid mediator derived from omega-3 eicosapentaenoic acid, protects against 2,4,6-trinitrobenzene sulfonic acid-induced colitis. Proc. Natl. Acad. Sci. U.S.A. 102: 7671-7676 (2005). *
Ariyan C, Salvalaggio P, Fecteau S, Deng S, Rogozinski L, Mandelbrot D, Sharpe A, Sayegh MH, Basadonna GP, Rothstein DM. Cutting edge: transplantation tolerance through enhanced CTLA-4 expression. J. Immunol. 171: 5673-5677 (2003). *
Armaka M, Apostolaki M, Jacques P, Kontoyiannis DL, Elewaut D, Kollias G. Mesenchymal cell targeting by TNF as a common pathogenic principle in chronic inflammatory joint and intestinal diseases. J. Exp. Med. 205: 331-337 (2008). *
Armananzas R, Calvo B, Inza I, Lopez-Hoyos M, Martinez-Taboada V, Ucar E, Bernales I, Fullaondo A, Larranaga P, Zubiaga AM. Microarray analysis of autoimmune diseases by machine learning procedures. IEEE Trans. Inf. Technol. Biomed. 13: 341-350 (2009). *
Armstrong JL, Redfern CP, Veal GJ. 13-cis Retinoic acid and isomerisation in paediatric oncology - is changing shape the key to success? Biochem. Pharmacol. 69: 1299-1306 (2005). *
Arnesano F, Bertini I. Structural genomics on metalloproteins. Gene Funct. Dis. 3: 49-55 (2002). *
Arnett FC. Genetic studies of human lupus in families. Int. Rev. Immunol. 19: 297-317 (2000).
Arnett FC, Shulman LE. Studies in familial systemic lupus erythematosus. Medicine (Baltimore) 55: 313-322 (1976).
Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL. BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation. J. Immunol. 178: 1523-1533 (2007). *
Arnett HA, Viney JL. Considerations for the sensible use of rodent models of inflammatory disease in predicting efficacy of new biological therapeutics in the clinic. Adv. Drug Deliv. Rev. 59: 1084-1092 (2007).
Arnold AP, Chen X. What does the "four core genotypes" mouse model tell us about sex differences in the brain and other tissues? Front. Neuroendocrinol. 30: 1-9 (2009).
Arnold KA, Eichelbaum M, Burk O. Alternative splicing affects the function and tissue-specific expression of the human constitutive androstane receptor. Nucl. Recept. 2: 1 (2004). *
Arredondo J, Chernyavsky AI, Jolkovsky DL, Webber RJ, Grando SA. SLURP-2: a novel cholinergic signaling peptide in human mucocutaneous epithelium. J. Cell. Physiol. 208: 238-245 (2006). *
Arredondo M, Jorquera D, Carrasco E, Albala C, Hertrampf E. Microsatellite polymorphism in the heme oxygenase-1 gene promoter is associated with iron status in persons with type 2 diabetes mellitus. Am. J. Clin. Nutr. 86: 1347-1353 (2007). *
Arrese M, Ananthanarayanan M. The bile salt export pump: molecular properties, function and regulation. Pflugers Arch. 449: 123-131 (2004). *
Arrese M, Miquel JF, Ananthanarayanan M. BetaKlotho: a new kid on the bile acid biosynthesis block. Hepatology 43: 191-193 (2006). *
Arruda SF, Siqueira EM, de Valencia FF. Vitamin A deficiency increases hepcidin expression and oxidative stress in rat. Nutrition 25: 472-478 (2009).
Arsenescu R, Bruno ME, Rogier EW, Stefka AT, McMahan AE, Wright TB, Nasser MS, de Villiers WJ, Kaetzel CS. Signature biomarkers in Crohn's disease: toward a molecular classification. Mucosal Immunol. 1: 399-411 (2008).
Artaza J, Norris K. Vitamin D reduces the expression of collagen and key profibrotic factors by inducing an antifibrotic phenotype in mesenchymal multipotent cells. J. Endocrinol. 200: 207-221 (2009). *
Arthur AT, Armati PJ, Bye C, Consortium SM, Heard RN, Stewart GJ, Pollard JD, Booth DR. Genes implicated in multiple sclerosis pathogenesis from consilience of genotyping and expression profiles in relapse and remission. BMC Med. Genet. 9: 17 (2008). *
Arthur MJ. Fibrogenesis. II. Metalloproteinases and their inhibitors in liver fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G245-G249 (2000). *
Artis D, Shapira S, Mason N, Speirs KM, Goldschmidt M, Caamano J, Liou HC, Hunter CA, Scott P. Differential requirement for NF-kappa B family members in control of helminth infection and intestinal inflammation. J. Immunol. 169: 4481-4487 (2002). *
Artis DR, Lin JJ, Zhang C, Wang W, Mehra U, Perreault M, Erbe D, Krupka HI, England BP, Arnold J, Plotnikov AN, Marimuthu A, Nguyen H, Will S, Signaevsky M, Kral J, Cantwell J, Settachatgull C, Yan DS, Fong D, Oh A, Shi S, Womack P, Powell B, et al. Scaffold-based discovery of indeglitazar, a PPAR pan-active anti-diabetic agent. Proc. Natl. Acad. Sci. U.S.A. 106: 262-267 (2009). *
Arukwe A, Nordbo B. Hepatic biotransformation responses in Atlantic salmon exposed to retinoic acids and 3,3',4,4'-tetrachlorobiphenyl (PCB congener 77). Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 147: 470-482 (2008). *
Aruna BV, Sela M, Mozes E. Suppression of myasthenogenic responses of a T cell line by a dual altered peptide ligand by induction of CD4+CD25+ regulatory cells. Proc. Natl. Acad. Sci. U.S.A. 102: 10285-10290 (2005). *
Arundel C, Lewis JH. Drug-induced liver disease in 2006. Curr. Opin. Gastroenterol. 23: 244-254 (2007).
Arya R, Mallik M, Lakhotia SC. Heat shock genes - integrating cell survival and death. J. Biosci. 32: 595-610 (2007). *
Arzuaga X, Reiterer G, Majkova Z, Kilgore MW, Toborek M, Hennig B. PPARalpha ligands reduce PCB-induced endothelial activation: possible interactions in inflammation and atherosclerosis. Cardiovasc. Toxicol. 7: 264-272 (2007). *
Arzuaga X, Ren N, Stromberg A, Black EP, Arsenescu V, Cassis LA, Majkova Z, Toborek M, Hennig B. Induction of gene pattern changes associated with dysfunctional lipid metabolism induced by dietary fat and exposure to a persistent organic pollutant. Toxicol. Lett. May 22 [Epub ahead of print] (2009). *
Asahina K, Tsai SY, Li P, Ishii M, Maxson RE Jr, Sucov HM, Tsukamoto H. Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development. Hepatology 49: 998-1011 (2009).
Asai Y, Makimura Y, Ogawa T. Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide. J. Med. Microbiol. 56: 459-465 (2007). *
Asaka JI, Terada T, Ogasawara K, Katsura T, Inui KI. Characterization of the basal promoter element of human organic cation transporter 2 (hOCT2) gene. J. Pharmacol. Exp. Ther. 321: 684-689 (2007). *
Asaka JI, Terada T, Okuda M, Katsura T, Inui KI. Androgen receptor is responsible for rat organic cation transporter 2 gene regulation but not for rOCT1 and rOCT3. Pharm. Res. 23: 697-704 (2006). *
Asakura H, Sugimura K, Funakoshi K. Molecular pathoimmunology of ulcerative colitis. Nippon Rinsho 54: 1170-1175 (1996).
Asano Y, Ihn H, Jinnin M, Mimura Y, Tamaki K. Involvement of alphavbeta5 integrin in the establishment of autocrine TGF-beta signaling in dermal fibroblasts derived from localized scleroderma. J. Invest. Dermatol. 126: 1761-1769 (2006). *
Asano Y, Ihn H, Yamane K, Jinnin M, Mimura Y, Tamaki K. Increased expression of integrin alpha(v)beta3 contributes to the establishment of autocrine TGF-beta signaling in scleroderma fibroblasts. J. Immunol. 175: 7708-7718 (2005). *
Asano Y, Iimuro Y, Son G, Hirano T, Fujimoto J. Hepatocyte growth factor promotes remodeling of murine liver fibrosis, accelerating recruitment of bone marrow-derived cells into the liver. Hepatol. Res. 37: 1080-1094 (2007). *
Asghar A, Gorski JC, Haehner-Daniels B, Hall SD. Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin. Drug Metab. Dispos. 30: 20-26 (2002). *
Ashikov A, Routier F, Fuhlrott J, Helmus Y, Wild MK, Gerardy-Schahn R, Bakker H. The human solute carrier gene SLC35B4 encodes a bifunctional nucleotide sugar transporter with specificity for UDP-xylose and UDP-N-acetylglucosamine. J. Biol. Chem. 280: 27230-27235 (2005). *
Ashino T, Arima Y, Shioda S, Iwakura Y, Numazawa S, Yoshida T. Effect of interleukin-6 neutralization on CYP3A11 and metallothionein-1/2 expressions in arthritic mouse liver. Eur. J. Pharmacol. 558: 199-207 (2007). *
Ashkar AA, Yao XD, Gill N, Sajic D, Patrick AJ, Rosenthal KL. Toll-like receptor (TLR)-3, but not TLR4, agonist protects against genital herpes infection in the absence of inflammation seen with CpG DNA. J. Infect. Dis. 190: 1841-1849 (2004). *
Ashman RF, Schaffer FM, Kemp JD, Yokoyama WM, Zhu ZB, Cooper MD, Volanakis JE. Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency. J. Clin. Immunol. 12: 406-414 (1992).
Ashwell JD, Lu FW, Vacchio MS. Glucocorticoids in T cell development and function. Annu. Rev. Immunol. 18: 309-345 (2000). *
Ashwood P, Harvey R, Verjee T, Wolstencroft R, Thompson RP, Powell JJ. Functional interactions between mucosal IL-1, IL-ra and TGF-beta 1 in ulcerative colitis. Inflamm. Res. 53: 53-59 (2004). *
Askar E, Bregadze R, Mertens J, Schweyer S, Rosenberger A, Ramadori G, Mihm S. TLR3 gene polymorphisms and liver disease manifestations in chronic hepatitis C. J. Med. Virol. 81: 1204-1211 (2009). *
Asling B, Jirholt J, Hammond P, Knutsson M, Walentinsson A, Davidson G, Agreus L, Lehmann A, Lagerstrom-Fermer M. Collagen type III alpha I (COL3A1) is a gastro-oesophageal reflux disease (GORD) susceptibility gene and a male risk factor for hiatus hernia (HH). Gut Apr 26 [Epub ahead of print] (2009).
Asnani S, Theuma P, Fonseca VA. PPARgamma agonists and vascular risk factors: potential effects on cardiovascular disease. Metab. Syndr. Relat. Disord. 1: 23-32 (2003).
Aspinall R. T cell development, ageing and interleukin-7. Mech. Ageing Dev. 127: 572-578 (2006).
Asquith DL, McInnes IB. Emerging cytokine targets in rheumatoid arthritis. Curr. Opin. Rheumatol. 19: 246-251 (2007). *
Assassi S, Tan FK. Genetics of scleroderma: update on single nucleotide polymorphism analysis and microarrays. Curr. Opin. Rheumatol. 17: 761-767 (2005).
Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J. Biol. Chem. 279: 22250-22257 (2004). *
Assenat E, Gerbal-Chaloin S, Larrey D, Saric J, Fabre JM, Maurel P, Vilarem MJ, Pascussi JM. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance. Hepatology 40: 951-960 (2004). *
Assi K, Mills J, Owen D, Ong C, St Arnaud R, Dedhar S, Salh B. Integrin-linked kinase regulates cell proliferation and tumor growth in murine colitis-associated carcinogenesis. Gut 57: 931-940 (2008).
Assi LK, Wong SH, Ludwig A, Raza K, Gordon C, Salmon M, Lord JM, Scheel-Toellner D. Tumor necrosis factor alpha activates release of B lymphocyte stimulator by neutrophils infiltrating the rheumatoid joint. Arthritis Rheum. 56: 1776-1786 (2007). *
Astapova I, Lee LJ, Morales C, Tauber S, Bilban M, Hollenberg AN. The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo. Proc. Natl. Acad. Sci. U.S.A. 105: 19544-19549 (2008). *
Asumalahti K, Veal C, Laitinen T, Suomela S, Allen M, Elomaa O, Moser M, de Cid R, Ripatti S, Vorechovsky I, Marcusson JA, Nakagawa H, Lazaro C, Estivill X, Capon F, Novelli G, Saarialho-Kere U, Barker J, Trembath R, Kere J; Psoriasis Consortium. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. Hum. Mol. Genet. 11: 589-597 (2002). *
Atalay A, Yildiz-Demirtepe S, Tatlipinar S, Sanli-Erdogan B, Cobankara V, Yildirim C, Bagci H, Atalay EO. HLA-B51 gene and its expression in association with Behcet's disease in Denizli province of Turkey. Mol. Biol. Rep. 35: 345-349 (2008). *
Atalay C, Deliloglu Gurhan I, Irkkan C, Gunduz U. Multidrug resistance in locally advanced breast cancer. Tumour Biol. 27: 309-318 (2006).
Atar D, Dyrberg T, Michelsen B, Karlsen A, Kofod H, M�lvig J, Lernmark A. Site-specific antibodies distinguish single amino acid substitutions in position 57 in HLA-DQ beta-chain alleles associated with insulin-dependent diabetes. J. Immunol. 143: 533-538 (1989).
Ates O, Dalyan L, Hatemi G, Hamuryudan V, Topal-Sarikaya A. Genetic susceptibility to Behcet's syndrome is associated with NRAMP1 (SLC11A1) polymorphism in Turkish patients. Rheumatol. Int. 29: 787-791 (2009). *
Ates O, Musellim B, Ongen G, Topal-Sarikaya A. NRAMP1 (SLC11A1): a plausible candidate gene for systemic sclerosis (SSc) with interstitial lung involvement. J. Clin. Immunol. 28: 73-77 (2008). *
Athyros VG, Kakafika AI, Tziomalos K, Karagiannis A, Mikhailidis DP. Antisense technology for the prevention or the treatment of cardiovascular disease: the next blockbuster? Expert Opin. Investig. Drugs 17: 969-972 (2008).
Atkins D, Breuckmann A, Schmahl GE, Binner P, Ferrone S, Krummenauer F, Storkel S, Seliger B. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma. Int. J. Cancer 109: 265-273 (2004). *
Atkins KB, Troen BR. Regulation of cathepsin D gene expression in HL-60 cells by retinoic acid and calcitriol. Cell Growth Differ. 6: 871-877 (1995).
Atkinson EM. American society of gene therapy - third annual meeting. IDrugs 3: 1009-1011 (2000).
Atkinson TJ. Toll-like receptors, transduction-effector pathways, and disease diversity: evidence of an immunobiological paradigm explaining all human illness? Int. Rev. Immunol. 27: 255-281 (2008).
Atreya I, Atreya R, Neurath MF. NF-kappaB in inflammatory bowel disease. J. Intern. Med. 263: 591-596 (2008). *
Atreya R, Neurath MF. Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer. Clin. Rev. Allergy Immunol. 28: 187-196 (2005).
Atta HM, Al-Hendy A, Salama SA, Shaker OG, Hammam OA. Low-dose simultaneous delivery of adenovirus encoding hepatocyte growth factor and vascular endothelial growth factor in dogs enhances liver proliferation without systemic growth factor elevation. Liver Int. Jun 3 [Epub ahead of print] (2009).
Atug O, Tahan V, Eren F, Tiftikci A, Imeryuz N, Hamzaoglu HO, Tozun N. Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma (PPARgamma) gene in inflammatory bowel disease. J. Gastrointestin. Liver Dis. 17: 433-437 (2008). *
Atzeni F, Boiardi L, Casali B, Farnetti E, Sarzi-Puttini P, Pipitone N, Olivieri I, Cantini F, Salvi F, La Corte R, Triolo G, Filippini D, Paolazzi G, Salvarani C. Lack of association of the 463 G/A myeloperoxidase promoter polymorphism with Behcet's disease in Italian patients. Rheumatology (Oxford) 46: 1547-1550 (2007). *
Aubareda A, Mulero MC, Perez-Riba M. Functional characterization of the calcipressin 1 motif that suppresses calcineurin-mediated NFAT-dependent cytokine gene expression in human T cells. Cell. Signal. 18: 1430-1438 (2006). *
Aubourg P. X-linked adrenoleukodystrophy. Ann. Endocrinol. (Paris) 68: 403-411 (2007).
Aubry EM, Odermatt A. Retinoic acid reduces glucocorticoid sensitivity in C2C12 myotubes by decreasing 11beta-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor activities. Endocrinology 150: 2700-2708 (2009). *
Auerbach SS, Dekeyser JG, Stoner MA, Omiecinski CJ. CAR2 displays unique ligand binding and RXRalpha heterodimerization characteristics. Drug Metab. Dispos. 35: 428-439 (2007). *
Auerbach SS, Stoner MA, Su S, Omiecinski CJ. Retinoid X receptor-dependent transactivation by a naturally occurring structural variant of human CAR (NR1I3). Mol. Pharmacol. 68: 1239-1253 (2005). *
Augello A, Tasso R, Negrini SM, Amateis A, Indiveri F, Cancedda R, Pennesi G. Bone marrow mesenchymal progenitor cells inhibit lymphocyte proliferation by activation of the programmed death 1 pathway. Eur. J. Immunol. 35: 1482-1490 (2005). *
Augello A, Tasso R, Negrini SM, Cancedda R, Pennesi G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum. 56: 1175-1186 (2007). *
Augereau P, Badia E, Carascossa S, Castet A, Fritsch S, Harmand PO, Jalaguier S, Cavailles V. The nuclear receptor transcriptional coregulator RIP140. Nucl. Recept. Signal. 4: e024 (2006). *
Augoustides-Savvopoulou P, Luka Z, Karyda S, Stabler SP, Allen RH, Patsiaoura K, Wagner C, Mudd SH. Glycine N-methyltransferase deficiency: a new patient with a novel mutation. J. Inherit. Metab. Dis. 26: 745-759 (2003). *
Augustin MT, Kokkonen J, Karttunen TJ. Duodenal cytotoxic lymphocytes in cow's milk protein sensitive enteropathy and coeliac disease. Scand. J. Gastroenterol. 40: 1398-1406 (2005). *
Aulisa L, Papaleo P, Pola E, Angelini F, Aulisa AG, Tamburrelli FC, Pola P, Logroscino CA. Association between IL-6 and MMP-3 gene polymorphisms and adolescent idiopathic scoliosis: a case-control study. Spine 32: 2700-2702 (2007).
Aune TM, Maas K, Moore JH, Olsen NJ. Gene expression profiles in human autoimmune disease. Curr. Pharm. Des. 9: 1905-1917 (2003).
Aune TM, Maas K, Parker J, Moore JH, Olsen NJ. Profiles of gene expression in human autoimmune disease. Cell. Biochem. Biophys. 40: 81-96 (2004).
Aune TM, Parker JS, Maas K, Liu Z, Olsen NJ, Moore JH. Co-localization of differentially expressed genes and shared susceptibility loci in human autoimmunity. Genet. Epidemiol. 27: 162-172 (2004). *
Aust DE, Haase M, Dobryden L, Markwarth A, Lohrs U, Wittekind C, Baretton GB, Tannapfel A. Mutations of the BRAF gene in ulcerative colitis-related colorectal carcinoma. Int. J. Cancer 115: 673-677 (2005). *
Aust S, Brucker B, Graf J, Klimpfinger M, Thalhammer T. Melatonin modulates acid/base transport in human pancreatic carcinoma cells. Cell. Physiol. Biochem. 18: 91-102 (2006). *
Autenrieth IB, Bucheler N, Bohn E, Heinze G, Horak I. Cytokine mRNA expression in intestinal tissue of interleukin-2 deficient mice with bowel inflammation. Gut 41: 793-800 (1997). *
Auth MK, Woitaschek D, Beste M, Schreiter T, Kim HS, Oppermann E, Joplin RE, Baumann U, Hilgard P, Nadalin S, Markus BH, Blaheta RA. Preservation of the synthetic and metabolic capacity of isolated human hepatocytes by coculture with human biliary epithelial cells. Liver Transpl. 11: 410-419 (2005). *
Autschbach F, Braunstein J, Helmke B, Zuna I, Schurmann G, Niemir ZI, Wallich R, Otto HF, Meuer SC. In situ expression of interleukin-10 in noninflamed human gut and in inflammatory bowel disease. Am. J. Pathol. 153: 121-130 (1998). *
Auwerx J, Avner P, Baldock R, Ballabio A, Balling R, Barbacid M, Berns A, Bradley A, Brown S, Carmeliet P, Chambon P, Cox R, Davidson D, Davies K, Duboule D, Forejt J, Granucci F, Hastie N, De Angelis MH, Jackson I, Kioussis D, et al. The European dimension for the mouse genome mutagenesis program. Nat. Genet. 36: 925-927 (2004). *
Auwerx J, Schoonjans K, Fruchart JC, Staels B. Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects. J. Atheroscler. Thromb. 3: 81-89 (1996).
Avallone R, Demers A, Rodrigue-Way A, Bujold K, Harb D, Anghel S, Wahli W, Marleau S, Ong H, Tremblay A. A growth hormone-releasing peptide that binds scavenger receptor CD36 and ghrelin receptor upregulates ABC sterol transporters and cholesterol efflux in macrophages through a PPARgamma-dependent pathway. Mol. Endocrinol. 20: 3165-3178 (2006). *
Avasarala JR, Chittur SV, George AD, Tine JA. Microarray analysis in B cells among siblings with/without MS - role for transcription factor TCF2. BMC Med. Genomics 1: 2 (2008). *
Avbelj M, Tahirovic H, Debeljak M, Kusekova M, Toromanovic A, Krzisnik C, Battelino T. High prevalence of thyroid peroxidase gene mutations in patients with thyroid dyshormonogenesis. Eur. J. Endocrinol. 156: 511-519 (2007). *
Averdam A, Kuhl H, Sontag M, Becker T, Hughes AL, Reinhardt R, Walter L. Genomics and diversity of the common marmoset monkey NK complex. J. Immunol. 178: 7151-7161 (2007). *
Aversa A, Caprio M, Rosano GM, Spera G. Endothelial effects of drugs designed to treat erectile dysfunction. Curr. Pharm. Des. 14: 3768-3778 (2009).
Avila E, Diaz L, Barrera D, Halhali A, Mendez I, Gonzalez L, Zuegel U, Steinmeyer A, Larrea F. Regulation of vitamin D hydroxylases gene expression by 1,25-dihydroxyvitamin D(3) and cyclic AMP in cultured human syncytiotrophoblasts. J. Steroid Biochem. Mol. Biol. 103: 90-96 (2007).
Avila MA, Berasain C, Torres L, Martin-Duce A, Corrales FJ, Yang H, Prieto J, Lu SC, Caballeria J, Rodes J, Mato JM. Reduced mRNA abundance of the main enzymes involved in methionine metabolism in human liver cirrhosis and hepatocellular carcinoma. J. Hepatol. 33: 907-914 (2000). *
Avila MA, Garcia-Trevijano ER, Martinez-Chantar ML, Latasa MU, Perez-Mato I, Martinez-Cruz LA, del Pino MM, Corrales FJ, Mato JM. S-Adenosylmethionine revisited: its essential role in the regulation of liver function. Alcohol 27: 163-167 (2002). *
Awane M, Andres PG, Li DJ, Reinecker HC. NF-kappa B-inducing kinase is a common mediator of IL-17-, TNF-alpha-, and IL-1 beta-induced chemokine promoter activation in intestinal epithelial cells. J. Immunol. 162: 5337-5344 (1999). *
Awara WM, El-Sisi AE, El-Refaei M, El-Naa MM, El-Desoky K. Insulinotropic and anti-inflammatory effects of rosiglitazone in experimental autoimmune diabetes. Rev. Diabet. Stud. 2: 146-156 (2005). *
Awasthi A, Carrier Y, Peron JP, Bettelli E, Kamanaka M, Flavell RA, Kuchroo VK, Oukka M, Weiner HL. A dominant function for interleukin 27 in generating interleukin 10-producing anti-inflammatory T cells. Nat. Immunol. 8: 1380-1389 (2007). *
Awasthi A, Riol-Blanco L, Jager A, Korn T, Pot C, Galileos G, Bettelli E, Kuchroo VK, Oukka M. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J. Immunol. 182: 5904-5908 (2009).
Ayaori M, Sawada S, Yonemura A, Iwamoto N, Ogura M, Tanaka N, Nakaya K, Kusuhara M, Nakamura H, Ohsuzu F. Glucocorticoid receptor regulates ATP-binding cassette transporter-A1 expression and apolipoprotein-mediated cholesterol efflux from macrophages. Arterioscler. Thromb. Vasc. Biol. 26: 163-168 (2006). *
Ayensu WK, Tchounwou PB. Microarray analysis of mercury-induced changes in gene expression in human liver carcinoma (HepG2) cells: importance in immune responses. Int. J. Environ. Res. Public Health 3: 141-173 (2006).
Ayroles JF, Carbone MA, Stone EA, Jordan KW, Lyman RF, Magwire MM, Rollmann SM, Duncan LH, Lawrence F, Anholt RR, Mackay TF. Systems genetics of complex traits in Drosophila melanogaster. Nat. Genet. 41: 299-307 (2009). *
Azarpira N, Aghdaie MH, Behzad-Behbahanie A, Geramizadeh B, Behzadi S, Malekhoseinie SA, Raisjalal GH, Rahsaz M, Pourgholami A, Sagheb F. Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation. Exp. Clin. Transplant. 4: 416-419 (2006).
Azim K, McManus R, Brophy K, Ryan A, Kelleher D, Reynolds JV. Genetic polymorphisms and the risk of infection following esophagectomy: positive association with TNF-alpha gene -308 genotype. Ann. Surg. 246: 122-128 (2007). *
Aziz A, Xiao CW, Cockell KA, Sarwar Gilani G, Cruz-Hernandez C, Nimal Ratnayake WM. Impact of dietary protein on lipid metabolism in hamsters is source-dependent and associated with changes in hepatic gene expression. Br. J. Nutr. 100: 503-511 (2008). *
Azmy IA, Balasubramanian SP, Wilson AG, Stephenson TJ, Cox A, Brown NJ, Reed MW. Role of tumour necrosis factor gene polymorphisms (-308 and -238) in breast cancer susceptibility and severity. Breast Cancer Res. 6: R395-R400 (2004). *
Azuz-Lieberman N, Markel G, Mizrahi S, Gazit R, Hanna J, Achdout H, Gruda R, Katz G, Arnon TI, Battat S, Zamir E, Adawi M, Mader R, Mandelboim O. The involvement of NK cells in ankylosing spondylitis. Int. Immunol. 17: 837-845 (2005). *
Azzi A, Gysin R, Kempna P, Munteanu A, Negis Y, Villacorta L, Visarius T, Zingg JM. Vitamin E mediates cell signaling and regulation of gene expression. Ann. N. Y. Acad. Sci. 1031: 86-95 (2004). *
Azzi A, Gysin R, Kempna P, Munteanu A, Villacorta L, Visarius T, Zingg JM. Regulation of gene expression by alpha-tocopherol. Biol. Chem. 385: 585-591 (2004).
Baader M, Gnerre C, Stegeman JJ, Meyer UA. Transcriptional activation of cytochrome P450 CYP2C45 by drugs is mediated by the chicken xenobiotic receptor (CXR) interacting with a phenobarbital response enhancer unit. J. Biol. Chem. 277: 15647-15653 (2002). *
Baadsgaard O, Fisher G, Voorhees JJ, Cooper KD. The role of immune system in the pathogenesis of psoriasis. J. Invest. Dermatol. 95: 32S-34S (1990). *
Baba MI, Kaul D, Grover A. Importance of blood cellular genomic profile in coronary heart disease. J. Biomed. Sci. 13: 17-26 (2006). *
Baba N, Kobashi H, Yamamoto K, Terada R, Suzuki T, Hakoda T, Okano N, Shimada N, Fujioka S, Iwasaki Y, Shiratori Y. Gene expression profiling in biliary epithelial cells of primary biliary cirrhosis using laser capture microdissection and cDNA microarray. Transl. Res. 148: 103-113 (2006). *
Baba T, Ishizu A, Ikeda H, Miyatake Y, Tsuji T, Suzuki A, Tomaru U, Yoshiki T. Chronic graft-versus-host disease-like autoimmune disorders spontaneously occurred in rats with neonatal thymus atrophy. Eur. J. Immunol. 35: 1731-1740 (2005). *
Babcock AA, Wirenfeldt M, Holm T, Nielsen HH, Dissing-Olesen L, Toft-Hansen H, Millward JM, Landmann R, Rivest S, Finsen B, Owens T. Toll-like receptor 2 signaling in response to brain injury: an innate bridge to neuroinflammation. J. Neurosci. 26: 12826-12837 (2006).
Babcock TA, Carlin JM. Transcriptional activation of indoleamine dioxygenase by interleukin 1 and tumor necrosis factor alpha in interferon-treated epithelial cells. Cytokine 12: 588-594 (2000).
Babidge W, Millard S, Roediger W. Sulfides impair short chain fatty acid beta-oxidation at acyl-CoA dehydrogenase level in colonocytes: implications for ulcerative colitis. Mol. Cell. Biochem. 181: 117-124 (1998).
Babu D, Lee JS, Park SY, Thapa D, Choi MK, Kim AR, Park YJ, Kim JA. Involvement of NF-kappaB in the inhibitory actions of Platycarya strobilacea on the TNF-alpha-induced monocyte adhesion to colon epithelial cells and chemokine expression. Arch. Pharm. Res. 31: 727-735 (2008). *
Babu D, Thapa D, Lee JS, Park SY, Kim AR, Kim YH, Yang HC, Kim JA. Inhibitory effects of an aqueous extract of Cornus kousa Burg. leaves on TNF-alpha-induced chemokine expression and monocyte adhesion to human colonic epithelial cells. Arch. Pharm. Res. 32: 91-98 (2009). *
Babu MM. Computational approaches to study transcriptional regulation. Biochem. Soc. Trans. 36: 758-765 (2008). *
Babu S, Blauvelt CP, Kumaraswami V, Nutman TB. Regulatory networks induced by live parasites impair both Th1 and Th2 pathways in patent lymphatic filariasis: implications for parasite persistence. J. Immunol. 176: 3248-3256 (2006). *
Babyatsky MW, Rossiter G, Podolsky DK. Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease. Gastroenterology 110: 975-984 (1996). *
Bach JP, Rinn B, Meyer B, Dodel R, Bacher M. Role of MIF in inflammation and tumorigenesis. Oncology 75: 127-133 (2008).
Bachem MG, Schunemann M, Ramadani M, Siech M, Beger H, Buck A, Zhou S, Schmid-Kotsas A, Adler G. Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells. Gastroenterology 128: 907-921 (2005). *
Bacher S, Schmitz ML. The NF-kappa B pathway as a potential target for autoimmune disease therapy. Curr. Pharm. Des. 10: 2827-2837 (2004).
Bachmann MP, Bartsch H, Gross JK, Maier SM, Gross TF, Workman JL, James JA, Farris AD, Jung B, Franke C, Conrad K, Schmitz M, Buttner C, Buyon JP, Semsei I, Harley JB, Rieber EP. Autoimmunity as a result of escape from RNA surveillance. J. Immunol. 177: 1698-1707 (2006). *
Backlund MG, Mann JR, Holla VR, Buchanan FG, Tai HH, Musiek ES, Milne GL,Katkuri S, Dubois RN. 15-Hydroxyprostaglandin dehydrogenase is downregulated in colorectal cancer. J. Biol. Chem. 280: 3217-3223 (2005). *
Badagnani I, Castro RA, Taylor TR, Brett CM, Huang CC, Stryke D, Kawamoto M, Johns SJ, Ferrin TE, Carlson EJ, Burchard EG, Giacomini KM. Interaction of methotrexate with OATP1A2 and its genetic variants. J. Pharmacol. Exp. Ther. 318: 521-529 (2006). *
Badot V, Galant C, Nzeusseu Toukap A, Theate I, Maudoux AL, Van den Eynde BJ, Durez P, Houssiau FA, Lauwerys BR. Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis. Arthritis Res. Ther. 11: R57 (2009). *
Badou A, Saoudi A, Dietrich G, Druet E, Druet P, Pelletier L. Mercuric chloride-induced autoimmunity. Curr. Protoc. Immunol. Chapter 15: Unit 15.15 (2001).
Bae E, Kim WJ, Kang YM, Suk K, Koh EM, Cha HS, Ahn KS, Huh TL, Lee WH. Glucocorticoid-induced tumour necrosis factor receptor-related protein-mediated macrophage stimulation may induce cellular adhesion and cytokine expression in rheumatoid arthritis. Clin. Exp. Immunol. 148: 410-418 (2007). *
Bae EH, Lee J, Ma SK, Kim IJ, Fr�ki�r J, Nielsen S, Kim SY, Kim SW. alpha-Lipoic acid prevents cisplatin-induced acute kidney injury in rats. Nephrol. Dial. Transplant. Apr 17 [Epub ahead of print] (2009).
Bae SC, Choi JK. Tumor suppressor activity of RUNX3. Oncogene 23: 4336-4340 (2004). *
Bae Y, Kemper JK, Kemper B. Repression of CAR-mediated transactivation of CYP2B genes by the orphan nuclear receptor, short heterodimer partner (SHP). DNA Cell Biol. 23: 81-91 (2004).
Bae YS, Lee JH, Choi SH, Kim S, Almazan F, Witztum JL, Miller YI. Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein. Toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ. Res. 104: 210-218 (2009).
Baechler EC, Batliwalla FM, Karypis G, Gaffney PM, Moser K, Ortmann WA, Espe KJ, Balasubramanian S, Hughes KM, Chan JP, Begovich A, Chang SY, Gregersen PK, Behrens TW. Expression levels for many genes in human peripheral blood cells are highly sensitive to ex vivo incubation. Genes Immun. 5: 347-353 (2004). *
Baechler EC, Batliwalla FM, Reed AM, Peterson EJ, Gaffney PM, Moser KL, Gregersen PK, Behrens TW. Gene expression profiling in human autoimmunity. Immunol. Rev. 210: 120-137 (2006). *
Baechler EC, Bauer JW, Slattery CA, Ortmann WA, Espe KJ, Novitzke J, Ytterberg SR, Gregersen PK, Behrens TW, Reed AM. An interferon signature in the peripheral blood of dermatomyositis patients is associated with disease activity. Mol. Med. 13: 59-68 (2007). *
Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, Yamaguchi K, Mishina Y, Martin DW, Shoieb A, McEntee MF, Eling TE. Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia. Gastroenterology 131: 1553-1560 (2006). *
Baek SJ, Wilson LC, Lee CH, Eling TE. Dual function of nonsteroidal anti-inflammatory drugs (NSAIDs): inhibition of cyclooxygenase and induction of NSAID-activated gene. J. Pharmacol. Exp. Ther. 301: 1126-1131 (2002). *
Baerwald CG, Panayi GS, Lanchbury JS. Corticotropin releasing hormone promoter region polymorphisms in rheumatoid arthritis. J. Rheumatol. 24: 215-216 (1997).
Baes M, Gulick T, Choi HS, Martinoli MG, Simha D, Moore DD. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. Mol. Cell Biol. 14: 1544-1552 (1994). *
Baeten D, Steenbakkers PG, Rijnders AM, Boots AM, Veys EM, De Keyser F. Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker. Arthritis Rheum. 50: 444-451 (2004). *
Baetz A, Frey M, Heeg K, Dalpke AH. Suppressor of cytokine signaling (SOCS) proteins indirectly regulate Toll-like receptor signaling in innate immune cells. J. Biol. Chem. 279: 54708-54715 (2004). *
Baev DV, Caielli S, Ronchi F, Coccia M, Facciotti F, Nichols KE, Falcone M. Impaired SLAM-SLAM homotypic interaction between invariant NKT cells and dendritic cells affects differentiation of IL-4/IL-10-secreting NKT2 cells in nonobese diabetic mice. J. Immunol. 181: 869-877 (2008).
Baganz NL, Horton RE, Calderon AS, Owens WA, Munn JL, Watts LT, Koldzic-Zivanovic N, Jeske NA, Koek W, Toney GM, Daws LC. Organic cation transporter 3: keeping the brake on extracellular serotonin in serotonin-transporter-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 105: 18976-18981 (2008). *
Bagdanoff JT, Donoviel MS, Nouraldeen A, Tarver J, Fu Q, Carlsen M, Jessop TC, Zhang H, Hazelwood J, Nguyen H, Baugh SD, Gardyan M, Terranova KM, Barbosa J, Yan J, Bednarz M, Layek S, Taylor J, Digeorge-Foushee AM, Gopinathan S, Bruce D, Smith T, et al. Inhibition of sphingosine-1-phosphate lyase for the treatment of autoimmune disorders. J. Med. Chem. May 21 [Epub ahead of print] (2009).
Bagga D, Wang L, Farias-Eisner R, Glaspy JA, Reddy ST. Differential effects of prostaglandin derived from omega-6 and omega-3 polyunsaturated fatty acids on COX-2 expression and IL-6 secretion. Proc. Natl. Acad. Sci. U.S.A. 100: 1751-1756 (2003). *
Baggio B, Musacchio E, Priante G. Polyunsaturated fatty acids and renal fibrosis: pathophysiologic link and potential clinical implications. J. Nephrol. 18: 362-367 (2005).
Bagnall RD, Roberts RG, Mirza MM, Torigoe T, Prescott NJ, Mathew CG. Novel isoforms of the CARD8 (TUCAN) gene evade a nonsense mutation. Eur. J. Hum. Genet. 16: 619-625 (2008). *
Bagnoli S, Putignano AL, Melean G, Baglioni S, Sestini R, Milla M, d'Albasio G, Genuardi M, Pacini F, Trallori G, Papi L. Susceptibility to refractory ulcerative colitis is associated with polymorphism in the hMLH1 mismatch repair gene. Inflamm. Bowel Dis. 10: 705-708 (2004). *
Bagnyukova TV, Tryndyak VP, Muskhelishvili L, Ross SA, Beland FA, Pogribny IP. Epigenetic downregulation of the suppressor of cytokine signaling 1 (Socs1) gene is associated with the STAT3 activation and development of hepatocellular carcinoma induced by methyl-deficiency in rats. Cell Cycle 7: 3202-3210 (2008).
Baharvand H, Hashemi SM, Shahsavani M. Differentiation of human embryonic stem cells into functional hepatocyte-like cells in a serum-free adherent culture condition. Differentiation 76: 465-477 (2008).
Bahn A, Ebbinghaus C, Ebbinghaus D, Ponimaskin EG, Fuzesi L, Burckhardt G, Hagos Y. Expression studies and functional characterization of renal human organic anion transporter 1 isoforms. Drug Metab. Dispos. 32: 424-430 (2004). *
Bahn A, Hagos Y, Rudolph T, Burckhardt G. Mutation of amino acid 475 of rat organic cation transporter 2 (rOCT2) impairs organic cation transport. Biochimie 86: 133-136 (2004).
Bai A, Hu P, Chen J, Song X, Chen W, Peng W, Zeng Z, Gao X. Blockade of STAT3 by antisense oligonucleotide in TNBS-induced murine colitis. Int. J. Colorectal Dis. 22: 625-635 (2007). *
Bai DS, Dai Z, Zhou J, Liu YK, Qiu SJ, Tan CJ, Shi YH, Huang C, Wang Z, He YF, Fan J. Capn4 overexpression underlies tumor invasion and metastasis after liver transplantation for hepatocellular carcinoma. Hepatology 49: 460-470 (2009).
Bai J, Odin JA. Apoptosis and the liver: relation to autoimmunity and related conditions. Autoimmun. Rev. 2: 36-42 (2003). *
Bai L, Kao JY, Law DJ, Merchant JL. Recruitment of ataxia-telangiectasia mutated to the p21(waf1) promoter by ZBP-89 plays a role in mucosal protection. Gastroenterology 131: 841-852 (2006). *
Bai L, Zimmer S, Rickes O, Rohleder N, Holthues H, Engel L, Leube R, Spessert R. Daily oscillation of gene expression in the retina is phase-advanced with respect to the pineal gland. Brain Res. 1203: 89-96 (2008).
Bai P, Houten SM, Huber A, Schreiber V, Watanabe M, Kiss B, de Murcia G, Auwerx J, Menissier-de Murcia J. PARP-2 controls adipocyte differentiation and adipose tissue function through the regulation of the activity of the RXR/PPARgamma heterodimer. J. Biol. Chem. 282: 37738-37746 (2007). *
Bai S, Kitaura H, Zhao H, Chen J, Muller JM, Schule R, Darnay B, Novack DV, Ross FP, Teitelbaum SL. FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner. J. Clin. Invest. 115: 2742-2751 (2005). *
Bai S, Stepkowski SM, Kahan BD, Brunner LJ. Metabolic interaction between cyclosporine and sirolimus. Transplantation 77: 1507-1512 (2004).
Bai XP, Li HL, Yang WY, Xiao JZ, Wang B, Du RQ, Lou DJ. Effects of fenofibrate on gene expression of carnitine palmitoyltransferase 1 in liver and skeletal muscle and its influence on insulin sensitivity. Zhonghua Yi Xue Za Zhi 88: 268-270 (2008).
Bai Y, Onuma H, Bai X, Medvedev AV, Misukonis M, Weinberg JB, Cao W, Robidoux J, Floering LM, Daniel KW, Collins S. Persistent NF-kappa B activation in Ucp2-/-mice leads to enhanced nitric oxide and inflammatory cytokine production. J. Biol. Chem. 280: 19062-19069 (2005). *
Bailey M, Haverson K, Inman C, Harris C, Jones P, Corfield G, Miller B, Stokes C. The development of the mucosal immune system pre- and post-weaning: balancing regulatory and effector function. Proc. Nutr. Soc. 64: 451-457 (2005). *
Bailey-Dell KJ, Hassel B, Doyle LA, Ross DD. Promoter characterization and genomic organization of the human breast cancer resistance protein (ATP-binding cassette transporter G2) gene. Biochim. Biophys. Acta 1520: 234-241 (2001). *
Baillat D, Leprivier G, Regnier D, Vintonenko N, Begue A, Stehelin D, Aumercier M. Stromelysin-1 expression is activated in vivo by Ets-1 through palindromic head-to-head Ets binding sites present in the promoter. Oncogene 25: 5764-5776 (2006). *
Baillie RA, Jump DB, Clarke SD. Specific effects of polyunsaturated fatty acids on gene expression. Curr. Opin. Lipidol. 7: 53-55 (1996).
Bailly-Maitre B, Fondevila C, Kaldas F, Droin N, Luciano F, Ricci JE, Croxton R, Krajewska M, Zapata JM, Kupiec-Weglinski JW, Farmer D, Reed JC. Cytoprotective gene bi-1 is required for intrinsic protection from endoplasmic reticulum stress and ischemia-reperfusion injury. Proc. Natl. Acad. Sci. U.S.A. 103: 2809-2814 (2006). *
Bain LJ, Feldman RA. Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice. Xenobiotica 33: 1173-1183 (2005). *
Bajmoczi M, Gadjeva M, Alper SL, Pier G, Golan DE. Cystic fibrosis transmembrane conductance regulator and caveolin-1 regulate epithelial cell internalization of Pseudomonas aeruginosa. Am. J. Physiol. Cell. Physiol. Apr 22 [Epub ahead of print] (2009). *
Bajwa A, Forster MA, Maiti A, Woolbright BL, Beckman MJ. Specific regulation of CYP27B1 and VDR in proximal versus distal renal cells. Arch. Biochem. Biophys. 477: 33-42 (2008). *
Bak-Romaniszyn L, Cedzynski M, Szemraj J, St Swierzko A, Zeman K, Kaluzynski A, Planeta-Malecka I. Mannan-binding lectin in children with chronic gastritis. Scand. J. Immunol. 63: 131-135 (2006). *
Baken KA, Ezendam J, Gremmer ER, de Klerk A, Pennings JL, Matthee B, Peijnenburg AA, van Loveren H. Evaluation of immunomodulation by Lactobacillus casei Shirota: immune function, autoimmunity and gene expression. Int. J. Food Microbiol. 112: 8-18 (2006). *
Baker KP. BLyS-an essential survival factor for B cells: basic biology, links to pathology and therapeutic target. Autoimmun. Rev. 3: 368-375 (2004).
Baker PR, Lin Y, Schopfer FJ, Woodcock SR, Groeger AL, Batthyany C, Sweeney S, Long MH, Iles KE, Baker LM, Branchaud BP, Chen YE, Freeman BA. Fatty acid transduction of nitric oxide signaling: identification of unsaturated fatty acid nitro derivatives and PPAR receptor-dependent signaling activity. J. Biol. Chem. 280: 42464-42475 (2005). *
Bakir F, Kher S, Pannala M, Wilson N, Nguyen T, Sircar I, Takedomi K, Fukushima C, Zapf J, Xu K, Zhang SH, Liu J, Morera L, Schneider L, Sakurai N, Jack R, Cheng JF. Discovery and structure-activity relationship studies of indole derivatives as liver X receptor (LXR) agonists. Bioorg. Med. Chem. Lett. 17: 3473-3479 (2007). *
Balaban YH, Korkusuz P, Simsek H, Gokcan H, Gedikoglu G, Pinar A, Hascelik G, Asan E, Hamaloglu E, Tatar G. Dipeptidyl peptidase IV (DDP IV) in NASH patients. Ann. Hepatol. 6: 242-250 (2007). *
Balabanov R, Strand K, Goswami R, McMahon E, Begolka W, Miller SD, Popko B. Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis. J. Neurosci. 27: 2013-2024 (2007). *
Balabanov R, Strand K, Kemper A, Lee JY, Popko B. Suppressor of cytokine signaling 1 expression protects oligodendrocytes from the deleterious effects of interferon-gamma. J. Neurosci. 26: 5143-5152 (2006).
Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Rosa-Leyva M, Vilardell-Tarres M. Transcript levels of DNA methyltransferases DNMT1, DNMT3A and DNMT3B in CD4+ T cells from patients with systemic lupus erythematosus. Immunology 124: 339-347 (2008). *
Balada E, Ordi-Ros J, Serrano-Acedo S, Martinez-Lostao L, Vilardell-Tarres M. Transcript overexpression of the MBD2 and MBD4 genes in CD4+ T cells from systemic lupus erythematosus patients. J. Leukoc. Biol. 81: 1609-1616 (2007). *
Balada E, Ordi-Ros J, Vilardell-Tarres M. DNA methylation and systemic lupus erythematosus. Ann. N. Y. Acad. Sci. 1108: 127-136 (2007). *
Balakathiresan NS, Bhattacharyya S, Gutti U, Long RP, Jozwik C, Huang W, Srivastava M, Pollard HB, Biswas R. Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. 296: L1012-L018 (2009). *
Balakrishnan A, Sussman DJ, Polli JE. Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT). Pharm. Res. 22: 1269-1280 (2005). *
Balandraud N, Gouret P, Danchin EG, Blanc M, Zinn D, Roudier J, Pontarotti P. A rigorous method for multigenic families' functional annotation: the peptidyl arginine deiminase (PADs) proteins family example. BMC Genomics 6: 153 (2005). *
Balasubramaniyan N, Shahid M, Suchy FJ, Ananthanarayanan M. Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G251-G260 (2005). *
Baldan A, Bojanic DD, Edwards PA. The ABCs of sterol transport. J. Lipid Res. 50: S80-S85 (2009). *
Baldan A, Relat J, Marrero PF, Haro D. Functional interaction between peroxisome proliferator-activated receptors-alpha and Mef-2C on human carnitine palmitoyltransferase 1beta (CPT1beta) gene activation. Nucleic Acids Res. 32: 4742-4749 (2004). *
Baldan A, Tarr P, Lee R, Edwards PA. ATP-binding cassette transporter G1 and lipid homeostasis. Curr. Opin. Lipidol. 17: 227-232 (2006).
Balesaria S, Pell RJ, Abbott LJ, Tasleem A, Chavele KM, Barley NF, Khair U, Simon A, Moriarty KJ, Brydon WG, Walters JR. Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. Eur. J. Gastroenterol. Hepatol. 20: 413-422 (2008).
Balint BL, Nagy L. Selective modulators of PPAR activity as new therapeutic tools in metabolic diseases. Endocr. Metab. Immune Disord. Drug Targets 6: 33-43 (2006).
Balistreri WF. Genetic liver disease. 54th Annual Meeting of the American Association for the Study of Liver Diseases (2003).
Balkhi MY, Fitzgerald KA, Pitha PM. Functional regulation of MyD88-activated interferon regulatory factor 5 by K63-linked polyubiquitination. Mol. Cell. Biol. 28: 7296-7308 (2008). *
Balladares S, Alaez C, Pujol J, Duran C, Navarro JL, Gorodezky C. Distribution of TAP gene polymorphisms and extended MHC haplotypes in Mexican Mestizos and in Seri Indians from northwest Mexico. Genes Immun. 3: 78-85 (2002). *
Ballardini G, Bianchi FB, Mirakian R, Fallani M, Pisi E, Bottazzo GF. HLA-A,B,C, HLA-D/DR and HLA-D/DQ expression on unfixed liver biopsy sections from patients with chronic liver disease. Clin. Exp. Immunol. 70: 35-46 (1987). *
Ballardini G, Mirakian R, Bianchi FB, Pisi E, Doniach D, Bottazzo GF. Aberrant expression of HLA-DR antigens on bileduct epithelium in primary biliary cirrhosis: relevance to pathogenesis. Lancet 2: 1009-1013 (1984).
Ballatori N, Fang F, Christian WV, Li N, Hammond CL. Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G179-G186 (2008). *
Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol. Chem. 390: 191-214 (2009). *
Bamba S, Lee CY, Brittan M, Preston S, Direkze N, Poulsom R, Alison M, Wright N, Otto W. Bone marrow transplantation ameliorates pathology in interleukin-10 knockout colitic mice. J. Pathol. 209: 265-273 (2006). *
Bamias G, Martin C, Mishina M, Ross WG, Rivera-Nieves J, Marini M, Cominelli F. Proinflammatory effects of TH2 cytokines in a murine model of chronic small intestinal inflammation. Gastroenterology 128: 654-666 (2005). *
Bamias G, Okazawa A, Rivera-Nieves J, Arseneau KO, De La Rue SA, Pizarro TT, Cominelli F. Commensal bacteria exacerbate intestinal inflammation but are not essential for the development of murine ileitis. J. Immunol. 178: 1809-1818 (2007). *
Ban H, Inoue M, Griesenbach U, Munkonge F, Chan M, Iida A, Alton EW, Hasegawa M. Expression and maturation of Sendai virus vector-derived CFTR protein: functional and biochemical evidence using a GFP-CFTR fusion protein. Gene Ther. 14: 1688-1694 (2007). *
Ban JO, Hwang IG, Kim TM, Hwang BY, Lee US, Jeong HS, Yoon YW, Kimz DJ, Hong JT. Anti-proliferate and pro-apoptotic effects of 2,3-dihydro-3,5-dihydroxy-6-methyl-4H-pyranone through inactivation of NF-kappaB in human colon cancer cells. Arch. Pharm. Res. 30: 1455-1463 (2007).
Ban Y, Ban Y, Taniyama M, Katagiri T. Vitamin D receptor initiation codon polymorphism in Japanese patients with Graves' disease. Thyroid 10: 475-480 (2000).
Ban Y, Ban Y, Taniyama M, Katagiri T. Vitamin D receptor initiation codon polymorphism in Japanese patients with Graves' disease. Thyroid 10: 375-380 (2000).
Ban Y, Davies TF, Greenberg DA, Concepcion ES, Tomer Y. The influence of human leucocyte antigen (HLA) genes on autoimmune thyroid disease (AITD): results of studies in HLA-DR3 positive AITD families. Clin. Endocrinol. (Oxf.) 57: 81-88 (2002). *
Ban Y, Tozaki T, Tobe T, Ban Y, Jacobson EM, Concepcion ES, Tomer Y. The regulatory T cell gene FOXP3 and genetic susceptibility to thyroid autoimmunity: an association analysis in Caucasian and Japanese cohorts. J. Autoimmun. 28: 201-207 (2007).
Banach-Petrosky W, Ouyang X, Gao H, Nader K, Ji Y, Suh N, Dipaola RS, Abate-Shen C. Vitamin D inhibits the formation of prostatic intraepithelial neoplasia in Nkx3.1; Pten mutant mice. Clin. Cancer Res. 12: 5895-5901 (2006). *
Banales JM, Masyuk TV, Bogert PS, Huang BQ, Gradilone SA, Lee SO, Stroope AJ, Masyuk AI, Medina JF, LaRusso NF. Hepatic cystogenesis is associated with abnormal expression and location of ion transporters and water channels in an animal model of autosomal recessive polycystic kidney disease. Am. J. Pathol. 173: 1637-1646 (2008). *
Banan A, Zhang L, Farhadi A, Fields JZ, Shaikh M, Forsyth CB, Choudhary S, Keshavarzian A. Critical role of the atypical lambda ({lambda}) isoform of PKC (PKC-{lambda}) in oxidant-induced disruption of the microtubule cytoskeleton and barrier function of intestinal epithelium. J. Pharmacol. Exp. Ther. 312: 458-471 (2005). *
Bandyopadhyay S, Soto-Nieves N, Macian F. Transcriptional regulation of T cell tolerance. Semin. Immunol. 19: 180-187 (2007). *
Banerjee A, Gerondakis S. Coordinating TLR-activated signaling pathways in cells of the immune system. Immunol. Cell Biol. 85: 420-424 (2007). *
Banerjee A, Gugasyan R, McMahon M, Gerondakis S. Diverse Toll-like receptors utilize Tpl2 to activate extracellular signal-regulated kinase (ERK) in hemopoietic cells. Proc. Natl. Acad. Sci. U.S.A. 103: 3274-3279 (2006). *
Banerjee A, Hussainzada N, Khandelwal A, Swaan PW. Electrostatic and potential cation-pi forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter. Biochem. J. 410: 391-400 (2008). *
Banerjee A, Ray A, Chang C, Swaan PW. Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry 44: 8908-8917 (2005). *
Banerjee S, Oneda B, Yap LM, Jewell DP, Matters GL, Fitzpatrick LR, Seibold F, Sterchi EE, Ahmad T, Lottaz D, Bond JS. MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease. Mucosal Immunol. 2: 220-231 (2009). *
Bangsow C, Rubins N, Glusman G, Bernstein Y, Negreanu V, Goldenberg D, Lotem J, Ben-Asher E, Lancet D, Levanon D, Groner Y. The RUNX3 gene - sequence, structure and regulated expression. Gene 279: 221-232 (2001).
Baniyash M. TCR zeta-chain downregulation: curtailing an excessive inflammatory immune response. Nat. Rev. Immunol. 4: 675-687 (2004). *
Banks C, Bateman A, Payne R, Johnson P, Sheron N. Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease. J. Pathol. 199: 28-35 (2003). *
Banks KE, Anderson AL, Tang H, Hughes DE, Costa RH, McLachlan A. Hepatocyte nuclear factor 3beta inhibits hepatitis B virus replication in vivo. J. Virol. 76: 12974-12980 (2002). *
Bannerman DD, Eiting KT, Winn RK, Harlan JM. FLICE-like inhibitory protein (FLIP) protects against apoptosis and suppresses NF-kappaB activation induced by bacterial lipopolysaccharide. Am. J. Pathol. 165: 1423-1431 (2004). *
Bannerman PG, Hahn A. Enhanced visualization of axonopathy in EAE using thy1-YFP transgenic mice. J. Neurol. Sci. 260: 23-32 (2007).
Banno T, Gazel A, Blumenberg M. Effects of tumor necrosis factor-alpha (TNFalpha) in epidermal keratinocytes revealed using global transcriptional profiling. J. Biol. Chem. 279: 32633-32642 (2004). *
Banno T, Gazel A, Blumenberg M. Pathway-specific profiling identifies the NFkB-dependent TNFa-regulated genes in epidermal keratinocytes. J. Biol. Chem. 280: 18973-18980 (2005). *
Bansal K, Narayana Y, Balaji KN. Inhibition of TNF-alpha-induced cyclooxygenase-2 expression by Mycobacterium bovis BCG in human alveolar epithelial A549 cells. Scand. J. Immunol. 69: 11-19 (2009). *
Bansal MB, Kovalovich K, Gupta R, Li W, Agarwal A, Radbill B, Alvarez CE, Safadi R, Fiel MI, Friedman SL, Taub RA. Interleukin-6 protects hepatocytes from CCl4-mediated necrosis and apoptosis in mice by reducing MMP-2 expression. J. Hepatol. 42: 548-556 (2005). *
Bantel H, Berg C, Vieth M, Stolte M, Kruis W, Schulze-Osthoff K. Mesalazine inhibits activation of transcription factor NF-kappaB in inflamed mucosa of patients with ulcerative colitis. Am. J. Gastroenterol. 95: 3452-3457 (2000). *
Bantis C, Heering PJ, Aker S, Schwandt C, Grabensee B, Ivens K. Influence of interleukin-10 gene G-1082A polymorphism on recurrent IgA nephropathy. J. Nephrol. 21: 941-946 (2008).
Bantis C, Heering PJ, Aker S, Siekierka M, Kuhr N, Grabensee B, Ivens K. Tumor necrosis factor-alpha gene G-308A polymorphism is a risk factor for the development of membranous glomerulonephritis. Am. J. Nephrol. 26: 12-15 (2006).
Banus HA, Vandebriel RJ, de Ruiter H, Dormans JA, Nagelkerke NJ, Mooi FR, Hoebee B, van Kranen HJ, Kimman TG. Host genetics of Bordetella pertussis infection in mice: significance of Toll-like receptor 4 in genetic susceptibility and pathobiology. Infect. Immun. 74: 2596-2605 (2006). *
Banus S, Pennings J, Vandebriel R, Wester P, Breit T, Mooi F, Hoebee B, Kimman T. Lung response to Bordetella pertussis infection in mice identified by gene-expression profiling. Immunogenetics 59: 555-564 (2007). *
Banyer JL, Halliday DC, Thomson SA, Hamilton NH. Combinations of IFN-gamma and IL-4 induce distinct profiles of dendritic cell-associated immunoregulatory properties. Genes Immun. 4: 427-440 (2003). *
Bao C, Guo J, Lin G, Hu M, Hu Z. TNFR gene-modified mesenchymal stem cells attenuate inflammation and cardiac dysfunction following MI. Scand. Cardiovasc. J. 42: 56-62 (2008).
Bao J, Wang Q, Zheng L, Qiu YR, Zeng FY, Yang CL, Huang XZ. RelB silencing in mouse bone-marrow derived dendritic cells mediated by lentiviral vector. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24: 857-860 (2008).
Bao L, Osawe I, Puri T, Lambris JD, Haas M, Quigg RJ. C5a promotes development of experimental lupus nephritis which can be blocked with a specific receptor antagonist. Eur. J. Immunol. 35: 2496-2506 (2005). *
Bao L, Zhou M, Wu L, Lu L, Goldowitz D, Williams RW, Cui Y. PolymiRTS database: linking polymorphisms in microRNA target sites with complex traits. Nucleic Acids Res. 35: D51-D54 (2007). *
Bao S, Beagley KW, Murray AM, Caristo V, Matthaei KI, Young IG, Husband AJ. Intestinal IgA plasma cells of the B1 lineage are IL-5 dependent. Immunology 94: 181-188 (1998). *
Bar-Yehuda S, Silverman MH, Kerns WD, Ochaion A, Cohen S, Fishman P. The anti-inflammatory effect of A(3) adenosine receptor agonists: a novel targeted therapy for rheumatoid arthritis. Expert Opin. Investig. Drugs 16: 1601-1613 (2007).
Baragiotta A, Floreani A, Agarwal K, Venturi C, Craggs A, Jones DEJ, Donaldson PT, Bassendine MF. Chemokine receptor 5 and primary biliary cirrhosis: a two-centre genetic association study. Liver Int. 24: 646-650 (2004). *
Baran W, Szepietowski JC, Mazur G, Baran E. TGF-beta(1) gene polymorphism in psoriasis vulgaris. Cytokine 38: 8-11 (2007).
Baran W, Szepietowski JC, Mazur G, Baran E. IL-6 and IL-10 promoter gene polymorphisms in psoriasis vulgaris. Acta Derm. Venereol. 88: 113-116 (2008). *
Baranek T, Debret R, Antonicelli F, Lamkhioued B, Belaaouaj A, Hornebeck W, Bernard P, Guenounou M, Le Naour R. Elastin receptor (spliced galactosidase) occupancy by elastin peptides counteracts proinflammatory cytokine expression in lipopolysaccharide-stimulated human monocytes through NF-kappaB down-regulation. J. Immunol. 179: 6184-6192 (2007). *
Baranova A, Liotta L, Petricoin E, Younossi ZM. The role of genomics and proteomics: technologies in studying non-alcoholic fatty liver disease. Clin. Liver Dis.11: 209-220 (2007).
Baranska M, Skretkowicz J. Prospects of gene therapy. Wiad. Lek. 60: 305-311 (2007).
Bararia D, Trivedi AK, Zada AA, Greif PA, Mulaw MA, Christopeit M, Hiddemann W, Bohlander SK, Behre G. Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha. Leukemia 22: 800-807 (2008).
Baratelli F, Lin Y, Zhu L, Yang SC, Heuze-Vourc'h N, Zeng G, Reckamp K, Dohadwala M, Sharma S, Dubinett SM. Prostaglandin E2 induces FOXP3 gene expression and T regulatory cell function in human CD4+ T cells. J. Immunol. 175: 1483-1490 (2005). *
Barbaux S, Poirier O, Godefroy T, Kleinert H, Blankenberg S, Cambien F, Tiret L. Differential haplotypic expression of the interleukin-18 gene. Eur. J. Hum. Genet. 15: 856-863 (2007). *
Barbe-Tuana FM, Klein D, Ichii H, Berman DM, Coffey L, Kenyon NS, Ricordi C, Pastori RL. CD40-CD40 ligand interaction activates proinflammatory pathways in pancreatic islets. Diabetes 55: 2437-2445 (2006). *
Barbeau WE, Bassaganya-Riera J, Hontecillas R. Putting the pieces of the puzzle together - a series of hypotheses on the etiology and pathogenesis of type 1 diabetes. Med. Hypotheses 68: 607-619 (2007).
Barbera MJ, Schluter A, Pedraza N, Iglesias R, Villarroya F, Giralt M. Peroxisome proliferator-activated receptor alpha activates transcription of the brown fat uncoupling protein-1 gene. A link between regulation of the thermogenic and lipid oxidation pathways in the brown fat cell. J. Biol. Chem. 276: 1486-1493 (2001). *
Barbier O, Duran-Sandoval D, Pineda-Torra I, Kosykh V, Fruchart JC, Staels B. Peroxisome proliferator-activated receptor alpha induces hepatic expression of the human bile acid glucuronidating UDP-glucuronosyltransferase 2B4 enzyme. J. Biol. Chem. 278: 32852-32860 (2003). *
Barbier O, Torra IP, Duguay Y, Blanquart C, Fruchart JC, Glineur C, Staels B. Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 22: 717-726 (2002). *
Barbier O, Torra IP, Sirvent A, Claudel T, Blanquart C, Duran-Sandoval D, Kuipers F, Kosykh V, Fruchart JC, Staels B. FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. Gastroenterology 124: 1926-1940 (2003). *
Barbier O, Trottier J, Kaeding J, Caron P, Verreault M. Lipid-activated transcription factors control bile acid glucuronidation. Mol. Cell. Biochem. 326: 3-8 (2009). *
Barbier O, Villeneuve L, Bocher V, Fontaine C, Torra IP, Duhem C, Kosykh V, Fruchart JC, Guillemette C, Staels B. The UDP-glucuronosyltransferase 1A9 enzyme is a peroxisome proliferator-activated receptor alpha and gamma target gene. J. Biol. Chem. 278: 13975-13983 (2003). *
Barbon A, Gervasoni A, Lavia L, Orlandi C, Jaskolski F, Perrais D, Barlati S. Human GluR6c, a functional splicing variants of GluR6, is mainly expressed in non-nervous cells. Neurosci. Lett. 434: 77-82 (2008).
Barbosa KV, de Souza AF, Chebli JM, Proietti FA, Meirelles RS, de Souza JL. Hereditary hemochromatosis: population screening based on phenotype in Brazilian blood donors. J. Clin. Gastroenterol. 39: 430-434 (2005).
Barcellos LF, Oksenberg JR, Begovich AB, Martin ER, Schmidt S, Vittinghoff E, Goodin DS, Pelletier D, Lincoln RR, Bucher P, Swerdlin A, Pericak-Vance MA, Haines JL, Hauser SL; Multiple Sclerosis Genetics Group. HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am. J. Hum. Genet. 72: 710-716 (2003). *
Barcellos LF, Oksenberg JR, Green AJ, Bucher P, Rimmler JB, Schmidt S, Garcia ME, Lincoln RR, Pericak-Vance MA, Haines JL, Hauser SL; Multiple Sclerosis Genetics Group. Genetic basis for clinical expression in multiple sclerosis. Brain 125: 150-158 (2002). *
Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Ucelli A, Savettieri G, Lincoln RL, Deloa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum. Mol. Genet. 15: 2813-2824 (2006). *
Barcellos LF, Schito AM, Rimmler JB, Vittinghoff E, Shih A, Lincoln R, Callier S, Elkins MK, Goodkin DE, Haines JL, Pericak-Vance MA, Hauser SL, Oksenberg JR. CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group. Immunogenetics 51: 281-288 (2000).
Barcelo-Coblijn G, Golovko MY, Weinhofer I, Berger J, Murphy EJ. Brain neutral lipids mass is increased in alpha-synuclein gene-ablated mice. J. Neurochem. 101: 132-141 (2007).
Barcelo-Coblijn G, Kitajka K, Puskas LG, Hogyes E, Zvara A, Hackler L Jr, Farkas T. Gene expression and molecular composition of phospholipids in rat brain in relation to dietary n-6 to n-3 fatty acid ratio. Biochim. Biophys. Acta 1632: 72-79 (2003). *
Barchet W, Wimmenauer V, Schlee M, Hartmann G. Accessing the therapeutic potential of immunostimulatory nucleic acids. Curr. Opin. Immunol. 20: 389-395 (2008).
Bardin N, Reumaux D, Geboes K, Colombel JF, Blot-Chabaud M, Sampol J, Duthilleul P, Dignat-George F. Increased expression of CD146, a new marker of the endothelial junction in active inflammatory bowel disease. Inflamm. Bowel Dis. 12: 16-21 (2006). *
Bardon S, Benelli C, Bernard-Gallon D, Blottiere H, Demarquoy J, Duee PH, Forest C. Dietary fatty acids and cancer: potential cellular and molecular mechanisms. Bull. Cancer 92: 697-707 (2005).
Baricordi OR, Stignani M, Melchiorri L, Rizzo R. HLA-G and inflammatory diseases. Inflamm. Allergy Drug Targets 7: 67-74 (2008).
Barile S, Medda E, Nistico L, Bordignon V, Cordiali-Fei P, Carducci M, Rainaldi A, Marinelli R, Bonifati C. Vascular endothelial growth factor gene polymorphisms increase the risk to develop psoriasis. Exp. Dermatol. 15: 368-376 (2006).
Barisani D, Ceroni S, Meneveri R, Cesana BM, Bardella MT. IL-10 polymorphisms are associated with early-onset celiac disease and severe mucosal damage in patients of Caucasian origin. Genet. Med. 8: 169-174 (2006).
Barish GD. Peroxisome proliferator-activated receptors and liver X receptors in atherosclerosis and immunity. J. Nutr. 136: 690-694 (2006). *
Barish GD, Atkins AR, Downes M, Olson P, Chong LW, Nelson M, Zou Y, Hwang H, Kang H, Curtiss L, Evans RM, Lee CH. PPARdelta regulates multiple proinflammatory pathways to suppress atherosclerosis. Proc. Natl. Acad. Sci. U.S.A. 105: 4271-4276 (2008). *
Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. A nuclear receptor atlas: macrophage activation. Mol. Endocrinol. 19: 2466-2477 (2005). *
Barish GD, Narkar VA, Evans RM. PPARdelta: a dagger in the heart of the metabolic syndrome. J. Clin. Invest. 116: 590-597 (2006). *
Barkauskaite V, Ek M, Popovic K, Harris HE, Wahren-Herlenius M, Nyberg F. Translocation of the novel cytokine HMGB1 to the cytoplasm and extracellular space coincides with the peak of clinical activity in experimentally UV-induced lesions of cutaneous lupus erythematosus. Lupus 16: 794-802 (2007).
Barker CL, McHale MT, Gillies AK, Waller J, Pearce DM, Osborne J, Hutchinson PE, Smith GM, Pringle JH. The development and characterization of an in vitro model of psoriasis. J. Invest. Dermatol. 123: 892-901 (2004). *
Barker DF, Husain A, Neale JR, Martini BD, Zhang X, Doll MA, Christopher States J, Hein DW. Functional properties of an alternative, tissue-specific promoter for human arylamine N-acetyltransferase 1. Pharmacogenet. Genomics 16: 515-525 (2006). *
Barker JN. Genetic aspects of psoriasis. Clin. Exp. Dermatol. 26: 321-325 (2001). *
Barker N, van Es JH, Kuipers J, Kujala P, van den Born M, Cozijnsen M, Haegebarth A, Korving J, Begthel H, Peters PJ, Clevers H. Identification of stem cells in small intestine and colon by marker gene Lgr5. Nature 449: 1003-1007 (2007). *
Barksby HE, Lea SR, Preshaw PM, Taylor JJ. The expanding family of interleukin-1 cytokines and their role in destructive inflammatory disorders. Clin. Exp. Immunol. 149: 217-225 (2007). *
Barksby HE, Milner JM, Patterson AM, Peake NJ, Hui W, Robson T, Lakey R, Middleton J, Cawston TE, Richards CD, Rowan AD. Matrix metalloproteinase 10 promotion of collagenolysis via procollagenase activation: implications for cartilage degradation in arthritis. Arthritis Rheum. 54: 3244-3253 (2006). *
Barksby HE, Nile CJ, Jaedicke KM, Taylor JJ, Preshaw PM. Differential expression of immunoregulatory genes in monocytes in response to Porphyromonas gingivalis and Escherichia coli lipopolysaccharide. Clin. Exp. Immunol. 156: 479-487 (2009). *
Barlic J, Zhang Y, Foley JF, Murphy PM. Oxidized lipid-driven chemokine receptor switch, CCR2 to CX3CR1, mediates adhesion of human macrophages to coronary artery smooth muscle cells through a peroxisome proliferator-activated receptor gamma-dependent pathway. Circulation 114: 807-819 (2006).
Barlow AK, He X, Janeway C Jr. Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells. J. Exp. Med. 187: 1403-1415 (1998). *
Barna BP, Malur A, Dalrymple H, Karnekar R, Culver DA, Abraham S, Singh RJ, Brescia D, Kavuru MS, Thomassen MJ. A novel 1,25-dihydroxyvitamin D-activin A pathway in human alveolar macrophages is dysfunctional in patients with pulmonary alveolar proteinosis (PAP). Autoimmunity 42: 56-62 (2009).
Barnes B, Lubyova B, Pitha PM. On the role of IRF in host defense. J. Interferon Cytokine Res. 22: 59-71 (2002).
Barnes BJ, Field AE, Pitha-Rowe PM. Virus-induced heterodimer formation between IRF-5 and IRF-7 modulates assembly of the IFNA enhanceosome in vivo and transcriptional activity of IFNA genes. J. Biol. Chem. 278: 16630-16641 (2003). *
Barnes BJ, Richards J, Mancl M, Hanash S, Beretta L, Pitha PM. Global and distinct targets of IRF-5 and IRF-7 during innate response to viral infection. J. Biol. Chem. 279: 45194-45207 (2004). *
Barnes KC, Grant A, Gao P, Baltadjieva D, Berg T, Chi P, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, Brummet ME, Stockton M, Watkins T, Gao L, Gittens M, Wills-Karp M, Cheadle C, Beck LA, Beaty TH, Becker KG, Garcia JG, Mathias RA. Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes. J. Allergy Clin. Immunol. 118: 70-77 (2006). *
Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken M, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE. Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases. Drug Metab. Dispos. 35: 1963-1969 (2007). *
Barnich N, Bringer MA, Claret L, Darfeuille-Michaud A. Involvement of lipoprotein NlpI in the virulence of adherent invasive Escherichia coli strain LF82 isolated from a patient with Crohn's disease. Infect. Immun. 72: 2484-2493 (2004). *
Barnich N, Darfeuille-Michaud A. Role of bacteria in the etiopathogenesis of inflammatory bowel disease. World J. Gastroenterol. 13: 5571-5576 (2007). *
Barnich N, Hisamatsu T, Aguirre JE, Xavier R, Reinecker HC, Podolsky DK. GRIM-19 interacts with NOD2 and serves as down-stream effector of anti-bacterial function in intestinal epithelial cells. J. Biol. Chem. 280: 19021-19026 (2005). *
Baron M, Davignon JL. Inhibition of IFN-gamma-induced STAT1 tyrosine phosphorylation by human CMV is mediated by SHP2. J. Immunol. 181: 5530-5536 (2008).
Barone F, Bombardieri M, Manzo A, Blades MC, Morgan PR, Challacombe SJ, Valesini G, Pitzalis C. Association of CXCL13 and CCL21 expression with the progressive organization of lymphoid-like structures in Sjogren's syndrome. Arthritis Rheum. 52: 1773-1784 (2005). *
Baroni A, Orlando M, Donnarumma G, Farro P, Iovene MR, Tufano MA, Buommino E. Toll-like receptor 2 (TLR2) mediates intracellular signalling in human keratinocytes in response to Malassezia furfur. Arch. Dermatol. Res. 297: 280-288 (2006). *
Baroni SS, Santillo M, Bevilacqua F, Luchetti M, Spadoni T, Mancini M, Fraticelli P, Sambo P, Funaro A, Kazlauskas A, Avvedimento EV, Gabrielli A. Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. N. Engl. J. Med. 354: 2667-2676 (2006). *
Barouch-Bentov R, Che J, Lee CC, Yang Y, Herman A, Jia Y, Velentza A, Watson J, Sternberg L, Kim S, Ziaee N, Miller A, Jackson C, Fujimoto M, Young M, Batalov S, Liu Y, Warmuth M, Wiltshire T, Cooke MP, Sauer K. A conserved salt bridge in the G loop of multiple protein kinases is important for catalysis and for in vivo Lyn function. Mol. Cell 33: 43-52 (2009). *
Baroukh N, Ravier MA, Loder MK, Hill EV, Bounacer A, Scharfmann R, Rutter GA, Van Obberghen E. MicroRNA-124a regulates Foxa2 expression and intracellular signaling in pancreatic beta-cell lines. J. Biol. Chem. 282: 19575-19588 (2007). *
Barra GB, Velasco LF, Pessanha RP, Campos AM, Moura FN, Dias SM, Polikarpov I, Ribeiro RC, Simeoni LA, Neves FA. Molecular mechanism of thyroid hormone action. Arq. Bras. Endocrinol. Metabol. 48: 25-39 (2004).
Barrera G, Toaldo C, Pizzimenti S, Cerbone A, Pettazzoni P, Dianzani MU, Ferretti C. The role of PPAR ligands in controlling growth-related gene expression and their interaction with lipoperoxidation products. PPAR Res. 2008: 524671 (2008). *
Barresi V, Grosso M, Vitarelli E, Tuccari G, Barresi G. 5-Lipoxygenase is coexpressed with Cox-2 in sporadic colorectal cancer: a correlation with advanced stage. Dis. Colon Rectum 50: 1576-1584 (2007). *
Barrett JC, Hansoul S, Nicolae DL, Cho JH, Duerr RH, Rioux JD, Brant SR, Silverberg MS, Taylor KD, Barmada MM, Bitton A, Dassopoulos T, Datta LW, Green T, Griffiths AM, Kistner EO, Murtha MT, Regueiro MD, Rotter JI, et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat. Genet. 40: 955-962 (2008). *
Barriere H, Bagdany M, Bossard F, Okiyoneda T, Wojewodka G, Gruenert D, Radzioch D, Lukacs GL. Revisiting the role of CFTR and counterion permeability in the pH regulation of endocytic organelles. Mol. Biol. Cell May 6 [Epub ahead of print] (2009). *
Barro Soria R, Spitzner M, Schreiber R, Kunzelmann K. Bestrophin 1 enables Ca2+ activated Cl- conductance in epithelia. J. Biol. Chem. Sep 26 [Epub ahead of print] (2006). *
Bartee E, McCormack A, Fruh K. Quantitative membrane proteomics reveals new cellular targets of viral immune modulators. PLoS Pathog. 2: e107 (2006). *
Bartholin L, Cyprian FS, Vincent D, Garcia CN, Martel S, Horvat B, Berthet C, Goddard-Leon S, Treilleux I, Rimokh R, Marie JC. Generation of mice with conditionally activated transforming growth factor beta signaling through the TbetaRI/ALK5 receptor. Genesis 46: 724-731 (2008). *
Bartholin L, Powers SE, Melhuish TA, Lasse S, Weinstein M, Wotton D. TGIF inhibits retinoid signaling. Mol. Cell. Biol. 26: 990-1001 (2006). *
Bartke A, Bonkowski M, Masternak M. THow diet interacts with longevity genes. Hormones (Athens) 7: 17-23 (2008).
Bartling TR, Drumm ML. Loss of CFTR results in reduction of histone deacetylase 2 in airway epithelial cells. Am. J. Physiol. Lung Cell. Mol. Physiol. May 1 [Epub ahead of print] (2009). *
Bartling TR, Drumm ML. Oxidative stress causes IL8 promoter hyperacetylation in cystic fibrosis airway cell models. Am. J. Respir. Cell. Mol. Biol. 40: 58-65 (2009). *
Bartolome MJ, Martinez-Taboda VM, Lopez-Hoyos M, Blanco R, Rodriguez-Valverde V. Familial aggregation of polymyalgia rheumatica and giant cell arteritis: genetic and T cell repertoire analysis. Clin. Exp. Rheumatol. 19: 259-264 (2001).
Barton GM, Medzhitov R. Toll-like receptors and their ligands. Curr. Top. Microbiol. Immunol. 270: 81-92 (2002).
Barton SG, Rampton DS, Winrow VR, Domizio P, Feakins RM. Expression of heat shock protein 32 (hemoxygenase-1) in the normal and inflamed human stomach and colon: an immunohistochemical study. Cell Stress Chaperones 8: 329-334 (2003). *
Bartz H, Avalos NM, Baetz A, Heeg K, Dalpke AH. Involvement of suppressors of cytokine signaling in Toll-like receptor-mediated block of dendritic cell differentiation. Blood 108: 4102-4108 (2006). *
Baruah P, Dumitriu IE, Malik TH, Cook HT, Dyson J, Scott D, Simpson E, Botto M. C1q enhances IFN-gamma production by antigen specific T cells via the CD40 co-stimulatory pathway on dendritic cells. Blood 113: 3485-3493 (2009). *
Barzon L, Stefani AL, Pacenti M, Palu G. Versatility of gene therapy vectors through viruses. Expert Opin. Biol. Ther. 5: 639-662 (2005).
Bas A, Forsberg G, Sjoberg V, Hammarstrom S, Hernell O, Hammarstrom ML. Aberrant extrathymic T cell receptor gene rearrangement in the small intestinal mucosa: a risk factor for celiac disease? Gut 58: 189-195 (2009). *
Basak GW, Yasukawa S, Alfaro A, Halligan S, Srivastava AS, Min WP, Minev B, Carrier E. Human embryonic stem cells-derived blast cells expres HLA-antigens. J. Transl. Med. 7: 27 (2009). *
Basak P, Adiloglu A, Koc I, Tas T, Akkaya V. Evaluation of activatory and inhibitory natural killer cell receptors in non-segmental vitiligo: a flow cytometric study. J. Eur. Acad. Dermatol. Venereol. May 8 [Epub ahead of print] (2008). *
Basarkar A, Singh J. Poly (lactide-co-glycolide)-polymethacrylate nanoparticles for intramuscular delivery of plasmid encoding interleukin-10 to prevent autoimmune diabetes in mice. Pharm. Res. 26: 72-81 (2009).
Bashir MM, Sharma MR, Werth VP. TNF-alpha production in the skin. Arch. Dermatol. Res. 301: 87-91 (2009). *
Basinski TM, Holzmann D, Eiwegger T, Zimmermann M, Klunker S, Meyer N, Schmid-Grendelmeier P, Jutel M, Akdis CA. Dual nature of T-cell-epithelium interaction in chronic rhinosinusitis. J. Allergy Clin. Immunol. Jun 10 [Epub ahead of print] (2009).
Basler T, Geffers R, Weiss S, Valentin-Weigand P, Goethe R. Mycobacterium avium subspecies induce differential expression of pro-inflammatory mediators in a murine macrophage model: Evidence for enhanced pathogenicity of Mycobacterium avium subspecies paratuberculosis. Immunobiology 213: 879-888 (2008).
Basler T, Jeckstadt S, Valentin-Weigand P, Goethe R. Mycobacterium paratuberculosis, Mycobacterium smegmatis, and lipopolysaccharide induce different transcriptional and post-transcriptional regulation of the IRG1 gene in murine macrophages. J. Leukoc. Biol. 79: 628-638 (2006). *
Basma H, Soto-Gutierrez A, Yannam GR, Liu L, Ito R, Yamamoto T, Ellis E, Carson SD, Sato S, Chen Y, Muirhead D, Navarro-Alvarez N, Wong RJ, Roy-Chowdhury J, Platt JL, Mercer DF, Miller JD, Strom SC, Kobayashi N, Fox IJ. Differentiation and transplantation of human embryonic stem cell-derived hepatocytes. Gastroenterology 136: 990-999.e4 (2009). *
Bassaganya-Riera J, Hontecillas R. CLA and n-3 PUFA differentially modulate clinical activity and colonic PPAR-responsive gene expression in a pig model of experimental IBD. Clin. Nutr. 25: 454-465 (2006).
Bassaganya-Riera J, Hontecillas R, Beitz DC. Colonic anti-inflammatory mechanisms of conjugated linoleic acid. Clin. Nutr. 21: 451-459 (2002).
Bassaganya-Riera J, Misyak S, Guri AJ, Hontecillas R. PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation. Cell. Immunol. May 5 [Epub ahead of print] (2009). *
Bassaganya-Riera J, Reynolds K, Martino-Catt S, Cui Y, Hennighausen L, Gonzalez F, Rohrer J, Benninghoff AU, Hontecillas R. Activation of PPAR gamma and delta by conjugated linoleic acid mediates protection from experimental inflammatory bowel disease. Gastroenterology 127: 777-791 (2004). *
Bassendine MF. Infectious etiology of primary biliary cirrhosis (PBC). Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 45-46 (2004). *
Bassett MH, Suzuki T, Sasano H, De Vries CJ, Jimenez PT, Carr BR, Rainey WE. The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase: implications for the control of adrenal functional zonation. J. Biol. Chem. 279: 37622-37630 (2004). *
Bassi MT, Manzoni M, Bresciani R, Pizzo MT, Della Monica A, Barlati S, Monti E, Borsani G. Cellular expression and alternative splicing of SLC25A23, a member of the mitochondrial Ca(2+)-dependent solute carrier gene family. Gene 345: 173-182 (2005). *
Basso K, Sumazin P, Morozov P, Schneider C, Maute RL, Kitagawa Y, Mandelbaum J, Haddad J Jr, Chen CZ, Califano A, Dalla-Favera R. Identification of the human mature B cell miRNome. Immunity 30: 744-752 (2009). *
Bassols J, Ortega FJ, Moreno-Navarrete JM, Peral B, Ricart W, Fernandez-Real JM. Study of the proinflammatory role of human differentiated omental adipocytes. J. Cell. Biochem. Jun 2 [Epub ahead of print] (2009).
Bastonero S, Gargouri M, Ortiou S, Gueant JL, Merten MD. Inhibition by TNF-alpha and IL-4 of cationic lipid mediated gene transfer in cystic fibrosis tracheal gland cells. J. Gene Med. 7: 1439-1449 (2005).
Bastonero S, Le Priol Y, Armand M, Bernard CS, Reynaud-Gaubert M, Olive D, Parzy D, de Bentzmann S, Capo C, Mege JL. New microbicidal functions of tracheal glands: defective anti-infectious response to Pseudomonas aeruginosa in cystic fibrosis. PLoS ONE 4: e5357 (2009). *
Basu S, Pathak SK, Banerjee A, Pathak S, Bhattacharyya A, Yang Z, Talarico S, Kundu M, Basu J. Execution of macrophage apoptosis by PE_PGRS33 of Mycobacterium tuberculosis is mediated by Toll-like receptor 2-dependent release of tumor necrosis factor-alpha. J. Biol. Chem. 282: 1039-1050 (2007). *
Basu-Modak S, Braissant O, Escher P, Desvergne B, Honegger P, Wahli W. Peroxisome proliferator-activated receptor beta regulates acyl-CoA synthetase 2 in reaggregated rat brain cell cultures. J. Biol. Chem. 274: 35881-35888 (1999). *
Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J. Invest. Dermatol. 105: 89S-94S (1995).
Bataille F, Rohrmeier C, Bates R, Weber A, Rieder F, Brenmoehl J, Strauch U, Farkas S, Furst A, Hofstadter F, Scholmerich J, Herfarth H, Rogler G. Evidence for a role of epithelial mesenchymal transition during pathogenesis of fistulae in Crohn's disease. Inflamm. Bowel Dis. 14: 1514-1527 (2008).
Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis. Semin. Liver Dis. 21: 437-451 (2001).
Bates IR, Libich DS, Wood DD, Moscarello MA, Harauz G. An Arg/Lys-->Gln mutant of recombinant murine myelin basic protein as a mimic of the deiminated form implicated in multiple sclerosis. Protein Expr. Purif. 25: 330-341 (2002). *
Bates JM, Akerlund J, Mittge E, Guillemin K. Intestinal alkaline phosphatase detoxifies lipopolysaccharide and prevents inflammation in zebrafish in response to the gut microbiota. Cell Host Microbe 2: 371-382 (2007). *
Bates JM, Mittge E, Kuhlman J, Baden KN, Cheesman SE, Guillemin K. Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation. Dev. Biol. 297: 374-386 (2006). *
Batheja N, Suriawinata A, Saxena R, Ionescu G, Schwartz M, Thung SN. Expression of p53 and PCNA in cholangiocarcinoma and primary sclerosing cholangitis. Mod. Pathol. 13: 1265-1268 (2000). *
Batista-Pinto C, Rocha E, Castro LF, Rodrigues P, Lobo-da-Cunha A. Seasonal and gender variation of peroxisome proliferator activated receptors expression in brown trout liver. Gen. Comp. Endocrinol. 161: 146-152 (2009). *
Batliwalla FM, Baechler EC, Xiao X, Li W, Balasubramanian S, Khalili H, Damle A, Ortmann WA, Perrone A, Kantor AB, Gulko PS, Kern M, Furie R, Behrens TW, Gregersen PK. Peripheral blood gene expression profiling in rheumatoid arthritis. Genes Immun. 6: 388-397 (2005). *
Batliwalla FM, Li W, Ritchlin CT, Xiao X, Brenner M, Laragione T, Shao T, Durham R, Kemshetti S, Schwarz E, Coe R, Kern M, Baechler EC, Behrens TW, Gregersen PK, Gulko PS. Microarray analyses of peripheral blood cells identifies unique gene expression signature in psoriatic arthritis. Mol. Med. 11: 21-29 (2005). *
Batra A, Zeitz M, Siegmund B. Adipokine signaling in inflammatory bowel disease. Inflamm. Bowel Dis. Apr 30 [Epub ahead of print] (2009).
Batrakova EV, Kelly DL, Li S, Li Y, Yang Z, Xiao L, Alakhova DY, Sherman S, Alakhov VY, Kabanov AV. Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85. Mol. Pharm. 3: 113-123 (2006). *
Batten M, Kljavin NM, Li J, Walter MJ, de Sauvage FJ, Ghilardi N. Cutting edge: IL-27 is a potent inducer of IL-10 but not FoxP3 in murine T cells. J. Immunol. 180: 2752-2756 (2008). *
Battle MA, Konopka G, Parviz F, Gaggl AL, Yang C, Sladek FM, Duncan SA. Hepatocyte nuclear factor 4alpha orchestrates expression of cell adhesion proteins during the epithelial transformation of the developing liver. Proc. Natl. Acad. Sci. U.S.A. 103: 8419-8424 (2006). *
Baudouin-Legros M, Hamdaoui N, Borot F, Fritsch J, Ollero M, Planelles G, Edelman A. Control of basal CFTR gene expression by bicarbonate-sensitive adenylyl cyclase in human pulmonary cells. Cell Physiol. Biochem. 21: 75-86 (2008). *
Baudouin-Legros M, Hinzpeter A, Jaulmes A, Brouillard F, Costes B, Fanen P, Edelman A. Cell-specific posttranscriptional regulation of CFTR gene expression via the influence of MAP kinase cascades on the 3'UTR part of the transcripts. Am. J. Physiol. Cell. Physiol. 289: C1240-C1250 (2005). *
Bauer JW, Bilgic H, Baechler EC. Gene-expression profiling in rheumatic disease: tools and therapeutic potential. Nat. Rev. Rheumatol. 5: 257-265 (2009).
Bauer M, Hamm AC, Bonaus M, Jacob A, Jaekel J, Schorle H, Pankratz MJ, Katzenberger JD. Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. Physiol. Genomics 17: 230-244 (2004). *
Baugh JA, Chitnis S, Donnelly SC, Monteiro J, Lin X, Plant BJ, Wolfe F, Gregersen PK, Bucala R. A functional promoter polymorphism in the macrophage migration inhibitory factor (MIF) gene associated with disease severity in rheumatoid arthritis. Genes Immun. 3: 170-176 (2002). *
Baum S, Barzilai A, Huszar M, Greenberger S, Trau H, Bank I. Very late antigen-1 in psoriasis: an immunohistochemical study. J. Eur. Acad. Dermatol. Venereol. 22: 283-289 (2008). *
Baumann U, Schmidt RE, Gessner JE. New insights into the pathophysiology and in vivo function of IgG Fc receptors through gene deletion studies. Arch. Immunol. Ther. Exp. (Warsz.) 51: 399-406 (2003).
Baumel M, Lechner A, Hehlgans T, Mannel DN. Enhanced susceptibility to Con A-induced liver injury in mice transgenic for the intracellular isoform of human TNF receptor type 2. J. Leukoc. Biol. 84: 162-169 (2008). *
Baumgardner JN, Shankar K, Korourian S, Badger TM, Ronis MJ. Undernutrition enhances alcohol-induced hepatocyte proliferation in the liver of rats fed via total enteral nutrition. Am. J. Physiol. Gastrointest. Liver Physiol. 293: G355-G364 (2007). *
Baumgart DC, Thomas S, Przesdzing I, Metzke D, Bielecki C, Lehmann SM, Lehnardt S, Dorffel Y, Sturm A, Scheffold A, Schmitz J, Radbruch A. Exaggerated inflammatory response of primary human myeloid dendritic cells to lipopolysaccharide in patients with inflammatory bowel disease. Clin. Exp. Immunol. [In Press] (2009). *
Baumhoer D, Tornillo L, Stadlmann S, Roncalli M, Diamantis EK, Terracciano LM. Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples. Am. J. Clin. Pathol. 129: 899-906 (2008).
Baus-Loncar M, Lubka M, Pusch CM, Otto WR, Poulsom R, Blin N. Cytokine regulation of the trefoil factor family binding protein GKN2 (GDDR/TFIZ1/blottin) in human gastrointestinal epithelial cells. Cell. Physiol. Biochem. 20: 193-204 (2007). *
Baxter SS, Carlson LA, Mayer AM, Hall ML, Fay MJ. Granulocytic differentiation of HL-60 promyelocytic leukemia cells is associated with increased expression of Cul5. In Vitro Cell. Dev. Biol. Anim. 45: 264-274 (2009).
Bayat A, Watson JS, Stanley JK, Ferguson MW, Ollier WE. Genetic susceptibility to Dupuytren disease: association of Zf9 transcription factor gene. Plast. Reconstr. Surg. 111: 2133-2139 (2003).
Bayle J, Fitch J, Jacobsen K, Kumar R, Lafyatis R, Lemaire R. Increased expression of Wnt2 and SFRP4 in Tsk mouse skin: role of Wnt signaling in altered dermal fibrillin deposition and systemic sclerosis. J. Invest. Dermatol. 128: 871-881 (2008). *
Bayou N, M'rad R, Ahlem B, Bechir Helayem M, Chaabouni H. Autism: an overview of genetic aetiology. Tunis. Med. 86: 573-578 (2008).
Bazan NG. Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations and Alzheimer's disease. J. Lipid Res. 50: S400-S405 (2009). *
Bazan NG. Cellular and molecular events mediated by docosahexaenoic acid-derived neuroprotectin D1 signaling in photoreceptor cell survival and brain protection. Prostaglandins Leukot. Essent. Fatty Acids Jun 9 [Epub ahead of print] (2009).
Bazan NG. Neurotrophins induce neuroprotective signaling in the retinal pigment epithelial cell by activating the synthesis of the anti-inflammatory and anti-apoptotic neuroprotectin D1. Adv. Exp. Med. Biol. 613: 39-44 (2008). *
Bazan NG. Lipid signaling in neural plasticity, brain repair, and neuroprotection. Mol. Neurobiol. 32: 89-103 (2005).
Bazhin AV, Schadendorf D, Owen RW, Zernii EY, Philippov PP, Eichmuller SB. Visible light modulates the expression of cancer-retina antigens. Mol. Cancer Res. 6: 110-118 (2008). *
Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, McIlrath J, Carr JM, Armit LJ, Clacher C, Malone L, Kollias G, Arthur JS. Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol. Cell. Biol. 25: 10454-10464 (2005). *
Beaumier CM, Harris LD, Goldstein S, Klatt NR, Whitted S, McGinty J, Apetrei C, Pandrea I, Hirsch VM, Brenchley JM. CD4 downregulation by memory CD4(+) T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nat. Med. Jun 14 [Epub ahead of print] (2009).
Beauquis J, Homo-Delarche F, Revsin Y, De Nicola AF, Saravia F. Brain alterations in autoimmune and pharmacological models of diabetes mellitus: focus on hypothalamic-pituitary-adrenocortical axis disturbances. Neuroimmunomodulation 15: 61-67 (2008).
Becanovic K, Jagodic M, Sheng JR, Dahlman I, Aboul-Enein F, Wallstrom E, Olofsson P, Holmdahl R, Lassmann H, Olsson T. Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis. J. Immunol. 176: 6055-6064 (2006). *
Bechmann LP, Zahn D, Gieseler RK, Fingas CD, Marquitan G, Jochum C, Gerken G, Friedman SL, Canbay A. Resveratrol amplifies profibrogenic effects of free fatty acids on human hepatic stellate cells. Hepatol. Res. 39: 601-608 (2009). *
Beck F, Plummer S, Senior PV, Byrne S, Green S, Brammar WJ. The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat. Proc. Biol. Sci. 247: 83-87 (1992).
Beck IM, Berghe WV, Gerlo S, Bougarne N, Vermeulen L, De Bosscher K, Haegeman G. Glucocorticoids and mitogen- and stress-induced protein kinase 1 inhibitors: possible partners in the combat against inflammation. Biochem. Pharmacol. 77: 1194-1205 (2009). *
Beck IM, Vanden Berghe W, Vermeulen L, Bougarne N, Vander Cruyssen B, Haegeman G, De Bosscher K. Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition. EMBO J. 27: 1682-1693 (2008). *
Beck PL, Podolsky DK. Growth factors in inflammatory bowel disease. Inflamm. Bowel Dis. 5: 44-60 (1999). *
Becker C, Dornhoff H, Neufert C, Fantini MC, Wirtz S, Huebner S, Nikolaev A, Lehr HA, Murphy AJ, Valenzuela DM, Yancopoulos GD, Galle PR, Karow M, Neurath MF. Cutting edge: IL-23 cross-regulates IL-12 production in T cell-dependent experimental colitis. J. Immunol. 177: 2760-2764 (2006). *
Becker C, Fantini MC, Wirtz S, Nikolaev A, Lehr HA, Galle PR, Rose-John S, Neurath MF. IL-6 signaling promotes tumor growth in colorectal cancer. Cell Cycle 4: 217-220 (2005). *
Becker C, Wirtz S, Blessing M, Pirhonen J, Strand D, Bechthold O, Frick J, Galle PR, Autenrieth I, Neurath MF. Constitutive p40 promoter activation and IL-23 production in the terminal ileum mediated by dendritic cells. J. Clin. Invest. 112: 693-706 (2003). *
Becker J, Delayre-Orthez C, Frossard N, Pons F. Regulation of inflammation by PPARs: a future approach to treat lung inflammatory diseases? Fundam. Clin. Pharmacol. 20: 429-447 (2006). *
Becker KG. The common variants/multiple disease hypothesis of common complex genetic disorders. Med. Hypotheses 62: 309-317 (2004).
Becker-Weimann S, Wolf J, Kramer A, Herzel H. A model of the mammalian circadian oscillator including the REV-ERBalpha module. Genome Inform. 15: 3-12 (2004).
Becquemont L, Camus M, Kriaa F, Barbu V, Charpentier B, Jaillon P. Low levels of lymphocyte MDR1 gene expression during early renal transplantation in patients treated with tacrolimus. Fundam. Clin. Pharmacol. 14: 225-229 (2000).
Becskei A, Grusby MJ. Contribution of IL-12R mediated feedback loop to Th1 cell differentiation. FEBS Lett. 581: 5199-5206 (2007). *
Bedrine-Ferran H, Le Meur N, Gicquel I, Le Cunff M, Soriano N, Guisle I, Mottier S, Monnier A, Teusan R, Fergelot P, Le Gall JY, Leger J, Mosser J. Transcriptome variations in human CaCo-2 cells: a model for enterocyte differentiation and its link to iron absorption. Genomics 83: 772-789 (2004). *
Beeton C, Wulff H, Standifer NE, Azam P, Mullen KM, Pennington MW, Kolski-Andreaco A, Wei E, Grino A, Counts DR, Wang PH, Leehealey CJ, S Andrews B, Sankaranarayanan A, Homerick D, Roeck WW, Tehranzadeh J, Stanhope KL, Zimin P, Havel PJ, Griffey S, et al. Kv1.3 channels are a therapeutic target for T cell-mediated autoimmune diseases. Proc. Natl. Acad. Sci. U.S.A. 103: 17414-17419 (2006). *
Beetz S, Wesch D, Marischen L, Welte S, Oberg HH, Kabelitz D. Innate immune functions of human gammadelta T cells. Immunobiology 213: 173-182 (2008).
Begni B, Amadori M, Ritelli M, Podavini D. Effects of IFN-alpha on the inflammatory response of swine leukocytes to bacterial endotoxin. J. Interferon. Cytokine Res. 25: 202-208 (2005).
Begue B, Dumant C, Bambou JC, Beaulieu JF, Chamaillard M, Hugot JP, Goulet O, Schmitz J, Philpott DJ, Cerf-Bensussan N, Ruemmele FM. Microbial induction of CARD15 expression in intestinal epithelial cells via Toll-like receptor 5 triggers an antibacterial response loop. J. Cell. Physiol. 209: 241-252 (2006). *
Begum-Haque S, Sharma A, Kasper IR, Foureau DM, Mielcarz DW, Haque A, Kasper LH. Downregulation of IL-17 and IL-6 in the central nervous system by glatiramer acetate in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 204: 58-65 (2008).
Behrendt M, Keiser M, Hoch M, Naim HY. Impaired trafficking and subcellular localization of a mutant lactase associated with congenital lactase deficiency. Gastroenterology 136: 2295-2303 (2009). *
Beigneux AP, Moser AH, Shigenaga JK, Grunfeld C, Feingold KR. The acute phase response is associated with retinoid X receptor repression in rodent liver. J. Biol. Chem. 275: 16390-16399 (2000). *
Beilke LD, Aleksunes L, Holland R, Besselsen DG, Beger RD, Klaassen CD, Cherrington N. Constitutive androstane receptor-mediated changes in bile acid composition contributes to hepatoprotection from lithocholic acid-induced liver injury in mice. Drug Metab. Dispos. 37: 1035-1045 (2009). *
Beketic-Oreskovic L, Duran GE, Chen G, Dumontet C, Sikic BI. Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833. J. Natl. Cancer Inst. 87: 1593-1602 (1995).
Bekpen C, Marques-Bonet T, Alkan C, Antonacci F, Leogrande MB, Ventura M, Kidd JM, Siswara P, Howard JC, Eichler EE. Death and resurrection of the human IRGM gene. PLoS Genet. 5: e1000403 (2009). *
Bel Hadj Jrad B, Mahfouth W, Bouaouina N, Gabbouj S, Ahmed SB, Ltaief M, Jalbout M, Chouchane L. A polymorphism in FAS gene promoter associated with increased risk of nasopharyngeal carcinoma and correlated with anti-nuclear autoantibodies induction. Cancer Lett. 233: 21-27 (2006). *
Belaguli NS, Zhang M, Rigi M, Aftab M, Berger DH. Cooperation between GATA4 and TGF-beta signaling regulates intestinal epithelial gene expression. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1520-G1533 (2007). *
Belakavadi M, Fondell JD. Role of the mediator complex in nuclear hormone receptor signaling. Rev. Physiol. Biochem. Pharmacol. 156: 23-43 (2006).
Belinsky GS, Parke AL, Huang Q, Blanchard K, Jayadev S, Stoll R, Rothe M, Achenie LE, Gupta RR, Wu GY, Rosenberg DW. The contribution of methotrexate exposure and host factors on transcriptional variance in human liver. Toxicol. Sci. 97: 582-594 (2007). *
Belkind-Gerson J, Carreon-Rodriguez A, Contreras-Ochoa CO, Estrada-Mondaca S, Parra-Cabrera MS. Fatty acids and neurodevelopment. J. Pediatr. Gastroenterol. Nutr. 47 Suppl. 1: S7-S9 (2008).
Bell AW, Michalopoulos GK. Phenobarbital regulates nuclear expression of HNF-4alpha in mouse and rat hepatocytes independent of CAR and PXR. Hepatology 44: 186-194 (2006). *
Bell MP, Svingen PA, Rahman MK, Xiong Y, Faubion WA. Forkhead box P3 regulates TLR10 expression in human T regulatory cells. J. Immunol. 179: 1893-1900 (2007). *
Bellanti JA, Sabra A, Zeligs BJ. Gastrointestinal immunopathology and food allergy. Ann. Allergy Asthma Immunol. 93: S26-S32 (2004).
Bellemere G, Von Stetten O, Oddos T. Retinoic acid increases aquaporin 3 expression in normal human skin. J. Invest. Dermatol. 128: 542-548 (2008). *
Bellezza I, Tucci A, Minelli A. 2-Chloroadenosine and human prostate cancer cells. Anticancer Agents Med. Chem. 8: 783-789 (2008).
Bellinger DL, Lorton D, Brouxhon S, Felten S, Felten DL. The significance of vasoactive intestinal polypeptide (VIP) in immunomodulation. Adv. Neuroimmunol. 6: 5-27 (1996).
Bellodi-Privato M, Aubert D, Pichard V, Myara A, Trivin F, Ferry N. Successful gene therapy of the Gunn rat by in vivo neonatal hepatic gene transfer using murine oncoretroviral vectors. Hepatology 42: 431-438 (2005). *
Beltowski J. Liver X receptors (LXR) as therapeutic targets in dyslipidemia. Cardiovasc. Ther. 26: 297-316 (2008).
Beltowski J, Wojcicka G, Jamroz A. Peroxisome proliferator-activated receptors (PPAR) in pathophysiology of the circulatory system and prospective use of agonists of these receptors in therapy. Postepy. Hig. Med. Dosw. 57: 199-217 (2003).
Belvederesi L, Bianchi F, Loretelli C, Gagliardini D, Galizia E, Bracci R, Rosati S, Bearzi I, Viel A, Cellerino R, Porfiri E. Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features. Eur. J. Hum. Genet. 14: 853-859 (2006). *
Belvisi MG, Hele DJ. Peroxisome proliferator-activated receptors as novel targets in lung disease. Chest 134: 152-157 (2008). *
Belvisi MG, Hele DJ, Birrell MA. Peroxisome proliferator-activated receptor gamma agonists as therapy for chronic airway inflammation. Eur. J. Pharmacol. 533: 101-109 (2006). *
Belyaeva OV, Johnson MP, Kedishvili NY. Kinetic analysis of human enzyme RDH10 defines the characteristics of a physiologically relevant retinol dehydrogenase. J. Biol. Chem. 283: 20299-20308 (2008). *
Ben Gedalya T, Loeb V, Israeli E, Altschuler Y, Selkoe DJ, Sharon R. alpha-Synuclein and polyunsaturated fatty acids promote clathrin mediated endocytosis and synaptic vesicle recycling. Traffic 10: 218-234 (2009). *
Ben-Shushan E, Marshak S, Shoshkes M, Cerasi E, Melloul D. A pancreatic beta-cell-specific enhancer in the human PDX-1 gene is regulated by hepatocyte nuclear factor 3beta (HNF-3beta), HNF-1alpha, and SPs transcription factors. J. Biol. Chem. 276: 17533-17540 (2001). *
Benakanakere MR, Li Q, Eskan MA, Singh AV, Zhao J, Galicia JC, Stathopoulou P, Knudsen TB, Kinane DF. Modulation of TLR2 protein expression by a miR-105 in human oral keratinocytes. J. Biol. Chem. Jun 9 [Epub ahead of print] (2009). *
Benatti P, Peluso G, Nicolai R, Calvani M. Polyunsaturated fatty acids: biochemical, nutritional and epigenetic properties. J. Am. Coll. Nutr. 23: 281-302 (2004). *
Bendinelli P, Piccoletti R, Maroni P. Leptin rapidly activates PPARs in C2C12 muscle cells. Biochem. Biophys. Res. Commun. 332: 719-725 (2005). *
Benigni A, Zoja C, Tomasoni S, Campana M, Corna D, Zanchi C, Gagliardini E, Garofano E, Rottoli D, Ito T, Remuzzi G. Transcriptional regulation of nephrin gene by peroxisome proliferator-activated receptor-gamma agonist: molecular mechanism of the antiproteinuric effect of pioglitazone. J. Am. Soc. Nephrol. 17: 1624-1632 (2006). *
Benito-Martin A, Ucero A, Santamar�a B, Lorz C, Kretzler M, Rastaldi M, Sanchez-Nino M, Sanz A, Izquierdo M, Ruiz Ortega M, Egido J, Ortiz A. Transcriptomics illustrate a deadly TRAIL to diabetic nephropathy. Nefrologia 29: 13-19 (2009).
Benjamin JT, Smith RJ, Halloran BA, Day TJ, Kelly DR, Prince LS. FGF-10 is decreased in bronchopulmonary dysplasia and suppressed by Toll-like receptor activation. Am. J. Physiol. Lung Cell. Mol. Physiol. 292: L550-L558 (2007). *
Benko S, Fantes JA, Amiel J, Kleinjan DJ, Thomas S, Ramsay J, Jamshidi N, Essafi A, Heaney S, Gordon CT, McBride D, Golzio C, Fisher M, Perry P, Abadie V, Ayuso C, Holder-Espinasse M, Kilpatrick N, Lees MM, Picard A, Temple IK, Thomas P, Vazquez MP, et al. Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence. Nat. Genet. 41: 359-364 (2009). *
Benlloch M, Ortega A, Ferrer P, Segarra R, Obrador E, Asensi M, Carretero J, Estrela JM. Acceleration of glutathione efflux and inhibition of gamma-glutamyl transpeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity. J. Biol. Chem. 280: 6950-6959 (2005). *
Bennett DJ, Carswell EL, Cooke AJ, Edwards AS, Nimz O. Design, structure activity relationships and X-ray co-crystallography of non-steroidal LXR agonists. Curr. Med. Chem. 15: 195-209 (2008).
Bennett ST, Wilson AJ, Cucca F, Nerup J, Pociot F, McKinney PA, Barnett AH, Bain SC, Todd JA. IDDM2-VNTR-encoded susceptibility to type 1 diabetes: dominant protection and parental transmission of alleles of the insulin gene-linked minisatellite locus. J. Autoimmun. 9: 415-421 (1996).
Bennetts BH, Teutsch SM, Buhler MM, Heard RN, Stewart GJ. The CCR5 deletion mutation fails to protect against multiple sclerosis. Hum. Immunol. 58: 52-59 (1997).
Bennouna S, Sukhumavasi W, Denkers EY. Toxoplasma gondii inhibits Toll-like receptor 4 ligand-induced mobilization of intracellular tumor necrosis factor alpha to the surface of mouse peritoneal neutrophils. Infect. Immun. 74: 4274-4281 (2006). *
Benoit S, Toksoy A, Brocker EB, Gillitzer R, Goebeler M. Treatment of recalcitrant pustular psoriasis with infliximab: effective reduction of chemokine expression. Br. J. Dermatol. 150: 1009-1012 (2004). *
Bensalem N, Ventura AP, Vallee B, Lipecka J, Tondelier D, Davezac N, Dos Santos A, Perretti M, Fajac A, Sermet-Gaudelus I, Renouil M, Lesure JF, Halgand F, Laprevote O, Edelman A. Down-regulation of the anti-inflammatory protein annexin A1 in cystic fibrosis knock-out mice and patients. Mol. Cell. Proteomics 4: 1591-1601 (2005). *
Bensi G, Raugei G, Klefenz H, Cortese R. Structure and expression of the human haptoglobin locus. EMBO J. 4: 119-126 (1985). *
Bensing S, Fetissov SO, Mulder J, Perheentupa J, Gustafsson J, Husebye ES, Oscarson M, Ekwall O, Crock PA, Hokfelt T, Hulting AL, Kampe O. Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. Proc. Natl. Acad. Sci. U.S.A. 104: 949-954 (2007). *
Benson EB, Strober W. Regulation of IgA secretion by T cell clones derived from the human gastrointestinal tract. J. Immunol. 140: 1874-1882 (1988).
Benson M, Carlsson L, Guillot G, Jernas M, Langston MA, Rudemo M, Andersson B. A network-based analysis of allergen-challenged CD4+ T cells from patients with allergic rhinitis. Genes Immun. 7: 514-521 (2006). *
Benten D, Kumaran V, Joseph B, Schattenberg J, Popov Y, Schuppan D, Gupta S. Hepatocyte transplantation activates hepatic stellate cells with beneficial modulation of cell engraftment in the rat. Hepatology 42: 1072-1081 (2005). *
Bentrem DJ, Joehl RJ. Pancreas: healing response in critical illness. Crit. Care Med. 31: S582-S589 (2003).
Benvenisty N, Reshef L. Regulation of tissue- and development-specific gene expression in the liver. Biol. Neonate 59: 181-189 (1991).
Benyon RC, Arthur MJ. Extracellular matrix degradation and the role of hepatic stellate cells. Semin. Liver Dis. 21: 373-384 (2001).
Benyon RC, Iredale JP, Goddard S, Winwood PJ, Arthur MJ. Expression of tissue inhibitor of metalloproteinases 1 and 2 is increased in fibrotic human liver. Gastroenterology 110: 821-831 (1996). *
Berard AM, Dumon MF, Darmon M. Dietary fish oil up-regulates cholesterol 7alpha-hydroxylase mRNA in mouse liver leading to an increase in bile acid and cholesterol excretion. FEBS Lett. 559: 125-128 (2004). *
Berasain C, Garcia-Trevijano ER, Castillo J, Erroba E, Lee DC, Prieto J, Avila MA. Amphiregulin: an early trigger of liver regeneration in mice. Gastroenterology 128: 424-432 (2005). *
Beraza N, Marques JM, Martinez-Anso E, Iniguez M, Prieto J, Bustos M. Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration. Hepatology 41: 460-469 (2005). *
Berberat PO, A-Rahim YI, Yamashita K, Warny MM, Csizmadia E, Robson SC, Bach FH. Heme oxygenase-1-generated biliverdin ameliorates experimental murine colitis. Inflamm. Bowel Dis. 11: 350-359 (2005). *
Bercher M, Hanson B, van Staden C, Wu K, Ng GY, Lee PH. Agonists of the orphan human G2A receptor identified from inducible G2A expression and beta-lactamase reporter screen. Assay Drug Dev. Technol. 7: 133-142 (2009).
Berchtold CM, Wu ZH, Huang TT, Miyamoto S. Calcium-dependent regulation of NEMO nuclear export in response to genotoxic stimuli. Mol. Cell. Biol. 27: 497-509 (2007). *
Berg PA, Klein R, Rocken M. Cytokines in primary biliary cirrhosis. Semin. Liver Dis. 17: 115-123 (1997).
Bergamaschi G. Two novel mutations, L490R and V561X, in transferrin receptor 2 in Japanese patients with hemochromatosis. Haematologica 90: 289A (2005). *
Bergann T, Zeissig S, Fromm A, Richter JF, Fromm M, Schulzke JD. Glucocorticoids and tumor necrosis factor-alpha synergize to induce colonic sodium absorption by the epithelial sodium channel. Gastroenterology 136: 933-942.e2 (2009). *
Bergasa NV. The pruritus of cholestasis. J. Hepatol. 43: 1078-1088 (2005). *
Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ. Primary biliary cirrhosis: report of a focus study group. Hepatology 40: 1013-1020 (2004). *
Bergen AA, Plomp AS, Gorgels TG, de Jong PT. From gene to disease; pseudoxanthoma elasticum and the ABCC6 gene. Ned. Tijdschr. Geneeskd. 148: 1586-1589 (2004).
Berger A, Mutch DM, German JB, Roberts MA. Dietary effects of arachidonate-rich fungal oil and fish oil on murine hepatic and hippocampal gene expression. Lipids Health Dis. 1: 2 (2002). *
Berger A, Mutch DM, German JB, Roberts MA. Unraveling lipid metabolism with microarrays: effects of arachidonate and docosahexaenoate acid on murine hepatic and hippocampal gene expression. Genome Biol. 3: PREPRINT0004 (2002). *
Berger J, Moller DE. The mechanisms of action of PPARs. Annu. Rev. Med. 53: 409-435 (2002). *
Berger J, Wagner JA. Physiological and therapeutic roles of peroxisome proliferator-activated receptors. Diabetes Technol. Ther. 4: 163-174 (2002).
Berghofer-Hochheimer Y, Zurek C, Langer G, Munder T. Expression of the vitamin D and the retinoid X receptors in Saccharomyces cerevisiae: alternative in vivo models for ligand-induced transactivation. J. Cell. Biochem. 66: 184-196 (1997). *
Bergholdt R, Karlsen AE, Hagedorn PH, Aalund M, Nielsen JH, Kruhoffer M, Orntoft T, Wang H, Wollheim CB, Nerup J, Pociot F. Transcriptional profiling of type 1 diabetes genes on chromosome 21 in a rat beta-cell line and human pancreatic islets. Genes Immun. 8: 232-238 (2007). *
Bergholdt R, Taxvig C, Eising S, Nerup J, Pociot F. CBLB variants in type 1 diabetes and their genetic interaction with CTLA4. J. Leukoc. 77: 579-585 (2005). *
Bergmann F, Breinig M, Hopfner M, Rieker RJ, Fischer L, Kohler C, Esposito I, Kleeff J, Herpel E, Ehemann V, Friess H, Schirmacher P, Kern MA. Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors? Am. J. Gastroenterol. 104: 171-181 (2009). *
Bergtold A, Gavhane A, D'Agati V, Madaio M, Clynes R. FcR-bearing myeloid cells are responsible for triggering murine lupus nephritis. J. Immunol. 177: 7287-7295 (2006). *
Beringer PM, Kriengkauykiat J, Zhang X, Hidayat L, Liu S, Louie S, Synold T, Burckart GJ, Rao PA, Shapiro B, Gill M. Lack of effect of P-glycoprotein inhibition on renal clearance of dicloxacillin in patients with cystic fibrosis. Pharmacotherapy 28: 883-894 (2008).
Beriou G, Costantino CM, Ashley CW, Yang L, Kuchroo VK, Baecher-Allan C, Hafler DA. IL-17 producing human peripheral regulatory T cells retain suppressive function. Blood 113: 4240-4249 (2009). *
Berkowitz CM, Shen CS, Bilir BM, Guibert E, Gumucio JJ. Different hepatocytes express the cholesterol 7 alpha-hydroxylase gene during its circadian modulation in vivo. Hepatology 21: 1658-1667 (1995).
Berlec A, Strukelj B. Novel applications of recombinant lactic acid bacteria in therapy and in metabolic engineering. Recent Pat. Biotechnol. 3: 77-87 (2009).
Berlin AL, Paller AS, Chan LS. Incontinentia pigmenti: a review and update on the molecular basis of pathophysiology. J. Am. Acad. Dermatol. 47: 169-187 (2002).
Bermudez B, Lopez S, Pacheco YM, Villar J, Muriana FJ, Hoheisel JD, Bauer A, Abia R. The influence of postprandial triglyceride-rich lipoproteins on lipid-mediated gene expression in smooth muscle cells of the human coronary artery. Cardiovasc. Res. 79: 294-303 (2008). *
Bermudo R, Abia D, Ferrer B, Nayach I, Benguria A, Zaballos A, Del Rey J, Miro R, Campo E, Martinez-A C, Ortiz AR, Fernandez PL, Thomson TM. Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer. BMC Cancer 8: 315 (2008). *
Bernales I, Fullaondo A, Marin-Vidalled MJ, Ucar E, Martinez-Taboada V, Lopez-Hoyos M, Zubiaga AM. Innate immune response gene expression profiles characterize primary antiphospholipid syndrome. Genes Immun. 9: 38-46 (2008). *
Bernardino AL, Myers TA, Alvarez X, Hasegawa A, Philipp MT. Toll-like receptors: insights into their possible role in the pathogeneis of Lyme neuroborreliosis. Infect. Immun. 76: 4385-4395 (2008). *
Bernardo AS, Hay CW, Docherty K. Pancreatic transcription factors and their role in the birth, life and survival of the pancreatic beta cell. Mol. Cell. Endocrinol. 294: 1-9 (2008).
Bernasconi P, Barberis M, Baggi F, Passerini L, Cannone M, Arnoldi E, Novellino L, Cornelio F, Mantegazza R. Increased Toll-like receptor 4 expression in thymus of myasthenic patients with thymitis and thymic involution. Am. J. Pathol. 167: 129-139 (2005). *
Bernatoniene J, Zhang Q, Dogan S, Mitchell TJ, Paton JC, Finn A. Induction of CC and CXC chemokines in human antigen-presenting dendritic cells by the pneumococcal proteins pneumolysin and CbpA, and the role played by Toll-like receptor 4, NF-kappaB, and mitogen-activated protein kinases. J. Infect. Dis. 198: 1823-1833 (2008). *
Berndt U, Philipsen L, Bartsch S, Wiedenmann B, Baumgart DC, Hammerle M, Sturm A. Systematic high-content proteomic analysis reveals substantial immunologic changes in colorectal cancer. Cancer Res. 68: 880-888 (2008). *
Bernotas RC, Singhaus RR, Kaufman DH, Ullrich J, Fletcher H 3rd, Quinet E, Nambi P, Unwalla R, Wilhelmsson A, Goos-Nilsson A, Farnegardh M, Wrobel J. Biarylether amide quinolines as liver X receptor agonists. Bioorg. Med. Chem. 17: 1663-1670 (2009). *
Bernstein H, Holubec H, Bernstein C, Ignatenko N, Gerner E, Dvorak K, Besselsen D, Ramsey L, Dall'Agnol M, Blohm-Mangone KA, Padilla-Torres J, Cui H, Garewal H, Payne CM. Unique dietary-related mouse model of colitis. Inflamm. Bowel Dis. 12: 278-293 (2006). *
Bernstein H, Holubec H, Bernstein C, Ignatenko NA, Gerner E, Dvorak K, Besselsen D, Blohm-Mangone KA, Padilla-Torres J, Dvorakova B, Garewal H, Payne CM. Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles. Dig. Dis. Sci. 52: 628-642 (2007). *
Bernstein H, Payne CM, Kunke K, Crowley-Weber CL, Waltmire CN, Dvorakova K, Holubec H, Bernstein C, Vaillancourt RR, Raynes DA, Guerriero V, Garewal H. A proteomic study of resistance to deoxycholate-induced apoptosis. Carcinogenesis 25: 681-692 (2004). *
Berrebi D, Maudinas R, Hugot JP, Chamaillard M, Chareyre F, De Lagausie P, Yang C, Desreumaux P, Giovannini M, Cezard JP, Zouali H, Emilie D, Peuchmaur M. Card15 gene overexpression in mononuclear and epithelial cells of the inflamed Crohn's disease colon. Gut 52: 840-846 (2003). *
Berrih-Aknin S. Myasthenia gravis, a model of organ-specific autoimmune disease. J. Autoimmun. 8: 139-143 (1995).
Berry DC, Noy N. All-trans-retinoic acid represses obesity and insulin resistance by activating both peroxisome proliferation-activated receptor beta/delta and retinoic acid receptor. Mol. Cell. Biol. 29: 3286-3296 (2009). *
Berstad AE, Brandtzaeg P. Expression of cell membrane complement regulatory glycoproteins along the normal and diseased human gastrointestinal tract. Gut 42: 522-529 (1998). *
Bertagnolli MM. Cyclooxygenase-2 as a target for prevention of colorectal cancer. Curr. Oncol. Rep. 1: 173-178 (1999).
Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH. The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis. Exp. Cell Res. 313: 1696-1709 (2007). *
Bertilsson G, Heidrich J, Svensson K, Asman M, Jendeberg L, Sydow-Backman M, Ohlsson R, Postlind H, Blomquist P, Berkenstam A. Identification of a human nuclear receptor defines a new signaling pathway for CYP3A induction. Proc. Natl. Acad. Sci. U.S.A. 95: 12208-12213 (1998). *
Bertolini A, Ottani A, Sandrini M. Selective COX-2 inhibitors and dual acting anti-inflammatory drugs: critical remarks. Curr. Med. Chem. 9: 1033-1043 (2002).
Bertolino P, Bowen DG, Zen M, Holz L, Davis T, McCaughan GW. Hepatocytes as targets of autoreactivity. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, p. 33 (2004). *
Bertolino P, Holz LE. Toll-like receptor-3 and the regulation of intrahepatic immunity: implications for interferon-alpha therapy. Hepatology 45: 250-251 (2007). *
Bertram JS, Vine AL. Cancer prevention by retinoids and carotenoids: independent action on a common target. Biochim. Biophys. Acta 1740: 170-178 (2005). *
Bertrand-Philippe M, Ruddell RG, Arthur MJ, Thomas J, Mungalsingh N, Mann DA. Regulation of tissue inhibitor of metalloproteinase-1 gene transcription by RUNX1 and RUNX2. J. Biol. Chem. 279: 24530-24539 (2004). *
Bertsias GK, Nakou M, Choulaki C, Raptopoulou A, Papadimitraki E, Goulielmos G, Kritikos H, Sidiropoulos P, Tzardi M, Kardassis D, Mamalaki C, Boumpas DT. Genetic, immunologic, and immunohistochemical analysis of the programmed death 1/programmed death ligand 1 pathway in human systemic lupus erythematosus. Arthritis Rheum. 60: 207-218 (2009). *
Bertucci F, Salas S, Eysteries S, Nasser V, Finetti P, Ginestier C, Charafe-Jauffret E, Loriod B, Bachelart L, Montfort J, Victorero G, Viret F, Ollendorff V, Fert V, Giovaninni M, Delpero JR, Nguyen C, Viens P, Monges G, Birnbaum D, Houlgatte R. Gene expression profiling of colon cancer by DNA microarrays and correlation with histoclinical parameters. Oncogene 23: 1377-1391 (2004). *
Besancon F, Przewlocki G, Baro I, Hongre AS, Escande D, Edelman A. Interferon-gamma downregulates CFTR gene expression in epithelial cells. Am. J. Physiol. 267: C1398-C1404 (1994).
Besnard P, Landrier JF, Grober J, Niot I. Is the ileal bile acid-binding protein (I-BABP) gene involved in cholesterol homeostasis? Med. Sci. (Paris) 20: 73-77 (2004).
Besnard V, Wert SE, Hull WM, Whitsett JA. Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues. Gene Expr. Patterns 5: 193-208 (2004). *
Besnard V, Xu Y, Whitsett JA. Sterol response element binding protein and thyroid transcription factor-1 (Nkx2.1) regulate Abca3 gene expression. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L1395-L405 (2007). *
Betser-Cohen G, Katz G, Gonen-Gross T, Stern N, Arnon TI, Achdout H, Gazit R, Mandelboim O. Reduced KIR2DL1 recognition of MHC class I molecules presenting phosphorylated peptides. J. Immunol. 176: 6762-6769 (2006). *
Bettelli E, Dastrange M, Oukka M. Foxp3 interacts with nuclear factor of activated T cells and NF-kappaB to repress cytokine gene expression and effector functions of T helper cells. Proc. Natl. Acad. Sci. U.S.A. 102: 5138-5143 (2005). *
Bettelli E, Oukka M, Kuchroo VK. T(H)-17 cells in the circle of immunity and autoimmunity. Nat. Immunol. 8: 345-350 (2007). *
Bettencourt R, Tanji T, Yagi Y, Ip YT. Toll and Toll-9 in Drosophila innate immune response. J. Endotoxin Res. 10: 261-268 (2004). *
Bettoun DJ, Burris TP, Houck KA, Buck DW 2nd, Stayrook KR, Khalifa B, Lu J, Chin WW, Nagpal S. Retinoid X receptor is a nonsilent major contributor to vitamin D receptor-mediated transcriptional activation. Mol. Endocrinol. 17: 2320-2328 (2003). *
Betz S, Kaser A, Nagaishi T, Yoshida M, Hussain M, vander Lugt B, Exley M, Blumberg RS. Lipids and IBD: microsomal triglyceride transfer protein - the new dimension? Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 23 (2005). *
Beuers U, Kullak-Ublick GA, Pusl T, Rauws ER, Rust C. Medical treatment of primary sclerosing cholangitis: a role for novel bile acids and other (post-)transcriptional modulators? Clin. Rev. Allergy Immunol. 36: 52-61 (2009). *
Bevins CL. Paneth cell defensins: key effector molecules of innate immunity. Biochem. Soc. Trans. 34: 263-266 (2006). *
Bevins CL. The role of gut flora and innate immunity in pathogenesis of inflammatory bowel disease. Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 58. September 12 - 13 (2003). *
Bevins CL. Defensins and other antibacterial mediators. Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 45 (2005). *
Bewry NN, Bolick SC, Wright KL, Harton JA. GTP-dependent recruitment of CIITA to the class II major histocompatibility complex promoter. J. Biol. Chem. 282: 26178-26184 (2007). *
Beyea MM, Heslop CL, Sawyez CG, Edwards JY, Markle JG, Hegele RA, Huff MW. Selective up-regulation of LXR-regulated genes ABCA1, ABCG1 and APOE in macrophages through increased endogenous synthesis of 24(S),25-epoxycholesterol. J. Biol. Chem. 282: 5207-5216 (2007). *
Beyer TP, Chen Y, Porter RK, Lu D, Schmidt RJ, Mantlo NB, Konrad RJ, Cao G. Peroxisome proliferator-activated receptor alpha agonists regulate cholesterol ester transfer protein. Lipids 43: 611-618 (2008).
Bezbradica JS, Medzhitov R. Integration of cytokine and heterologous receptor signaling pathways. Nat. Immunol. 10: 333-339 (2009). *
Bhadhprasit W, Sakuma T, Hatakeyama N, Fuwa M, Kitajima K, Nemoto N. Involvement of glucocorticoid receptor and pregnane X receptor in the regulation of mouse CYP3A44 female-predominant expression by glucocorticoid hormone. Drug Metab. Dispos. 35: 1880-1885 (2007). *
Bhagat G, Naiyer AJ, Shah JG, Harper J, Jabri B, Wang TC, Green PH, Manavalan JS. Small intestinal CD8+TCRgammadelta+NKG2A+ intraepithelial lymphocytes have attributes of regulatory cells in patients with celiac disease. J. Clin. Invest. 118: 281-293 (2008). *
Bhalla S, Ozalp C, Fang S, Xiang L, Kemper JK. Ligand-activated PXR interferes with HNF-4 signaling by targeting a common coactivator PGC-1alpha: functional implications in hepatic cholesterol and glucose metabolism. J. Biol. Chem. 279: 45139-45147 (2004). *
Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. Mol. Immunol. 45: 2214-2224 (2008). *
Bhat MK, Ashizawa K, Cheng SY. Phosphorylation enhances the target gene sequence-dependent dimerization of thyroid hormone receptor with retinoid X receptor. Proc. Natl. Acad. Sci. U.S.A. 91: 7927-7931 (1994). *
Bhat R, Bresnick E. Glycine N-methyltransferase is an example of functional diversity. Role as a polycyclic aromatic hydrocarbon-binding receptor. J. Biol. Chem. 272: 21221-21226 (1997). *
Bhatnagar V, Xu G, Hamilton BA, Truong DM, Eraly SA, Wu W, Nigam SK. Analyses of 5' regulatory region polymorphisms in human SLC22A6 (OAT1) and SLC22A8 (OAT3). J. Hum. Genet. 51: 575-580 (2006). *
Bhattacharyya Majumdar S, Dey R, Majumder N, Bhattacharjee S, Majumdar S. A novel approach to regulate experimental visceral leishmaniasis in murine macrophages using CCR5 siRNA. Scand. J. Immunol. 67: 345-353 (2008). *
Bhaumik D, Scott GK, Schokrpur S, Patil CK, Campisi J, Benz CC. Expression of microRNA-146 suppresses NF-kappaB activity with reduction of metastatic potential in breast cancer cells. Oncogene May 26 [Epub ahead of print] (2008). *
Bhavsar MD, Amiji MM. Polymeric nano- and microparticle technologies for oral gene delivery. Expert Opin. Drug Deliv. 4: 197-213 (2007).
Bhavsar MD, Amiji MM. Oral IL-10 gene delivery in a microsphere-based formulation for local transfection and therapeutic efficacy in inflammatory bowel disease. Gene Ther. 15: 1200-1209 (2008).
Bhavsar PK, Sukkar MB, Khorasani N, Lee KY, Chung KF. Glucocorticoid suppression of CX3CL1 (fractalkine) by reduced gene promoter recruitment of NF-kappaB. FASEB J. 22: 1807-1816 (2008). *
Bhavsar SK, Singh S, Giri S, Jain MR, Santani DD. Effect of saponins from Helicteres isora on lipid and glucose metabolism regulating genes expression. J. Ethnopharmacol. Jun 5 [Epub ahead of print] (2009).
Bhide MR, Mucha R, Mikula I Jr, Kisova L, Skrabana R, Novak M, Mikula I Sr. Novel mutations in TLR genes cause hyporesponsiveness to Mycobacterium avium subsp. paratuberculosis infection. BMC Genet. 10: 21 (2009). *
Bhojani MS, Hamstra DA, Chang DC, Coppola JM, Khan AP, Reddy GR, Ross BD, Rehemtulla A. Imaging of proteolytic activity using a conditional cell surface receptor. Mol. Imaging 5: 129-137 (2006).
Bhura-Bandali FN, Suh M, Man SF, Clandinin MT. The deltaF508 mutation in the cystic fibrosis transmembrane conductance regulator alters control of essential fatty acid utilization in epithelial cells. J. Nutr. 130: 2870-2875 (2000). *
Bhutani M, Pathak AK, Nair AS, Kunnumakkara AB, Guha S, Sethi G, Aggarwal BB. Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation. Clin. Cancer Res. 13: 3024-3032 (2007). *
Bi Y, Sun WP, Chen X, Li M, Liang H, Cai MY, Zhu YH, He XY, Xu F, Weng JP. Effect of early insulin therapy on nuclear factor kappaB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats. Acta Diabetol. 45: 167-178 (2008).
Bialecka M, Hnatyszyn G, Bielicka-Cymerman J, Drozdzik M. The effect of MDR1 gene polymorphism in the pathogenesis and the treatment of drug-resistant epilepsy. Neurol. Neurochir. Pol. 39: 476-481 (2005).
Bian GX, Miao H, Qiu L, Cao DM, Guo BY. Profiling of differentially expressed chemotactic-related genes in MCP-1 treated macrophage cell line using human cDNA arrays. World J. Gastroenterol. 11: 2508-2512 (2005). *
Bian ZM, Elner SG, Elner VM. Regulated expression of truncated short variants of caspase-12 mRNA in human retinal pigment epithelial cells suggests their immunomodulating role. Invest. Ophthalmol. Vis. Sci. 49: 5593-5601 (2008). *
Bianchi MG, Gazzola GC, Cagnin S, Kagechika H, Bussolati O. The ATRA-dependent overexpression of the glutamate transporter EAAC1 requires RARbeta induction. Biochim. Biophys. Acta May 15 [Epub ahead of print] (2009). *
Bianchi MG, Gazzola GC, Tognazzi L, Bussolati O. C6 glioma cells differentiated by retinoic acid overexpress the glutamate transporter excitatory amino acid carrier 1 (EAAC1). Neuroscience 151: 1042-1052 (2008).
Bianchi T, Pincus LB, Wurbel MA, Rich BE, Kupper TS, Fuhlbrigge RC, Boes M. Maintenance of peripheral tolerance through controlled tissue homing of antigen-specific T cells in K14-mOVA mice. J. Immunol. 182: 4665-4674 (2009).
Biancone L, Palmieri G, Lombardi A, Vavassori P, Monteleone I, Del Vecchio Blanco G, Colantoni A, Spagnoli L, Tonelli F, Pallone F. Cytoskeletal proteins and resident flora. Dig. Liver Dis. 34 Suppl. 2: S34-S36 (2002).
Biasi F, Mascia C, Poli G. TGFbeta1 expression in colonic mucosa: modulation by dietary lipids. Genes Nutr. 2: 233-243 (2007). *
Bickenbach KA, Veerapong J, Shao MY, Mauceri HJ, Posner MC, Kron SJ, Weichselbaum RR. Resveratrol is an effective inducer of CArG-driven TNF-alpha gene therapy. Cancer Gene Ther. 15: 133-139 (2008).
Bickston SJ, Comerford LW, Cominelli F. Future therapies for inflammatory bowel disease. Curr. Gastroenterol. Rep. 5: 518-523 (2003).
Bienvenu T. Cystic fibrosis: relationship between genotype and phenotype. Arch. Pediatr. 10 Suppl. 2: 318s-324s (2003).
Biernacka JM, Sun L, Bull SB. Simultaneous localization of two linked disease susceptibility genes. Genet. Epidemiol. 28: 33-47 (2004). *
Biesalski HK, Tinz J. Nutritargeting. Adv. Food Nutr. Res. 54: 179-217 (2008).
Bigger B, Coutelle C. Perspectives on gene therapy for cystic fibrosis airway disease. BioDrugs 15: 615-634 (2001).
Bigliardi PL, Stammer H, Jost G, Rufli T, Buchner S, Bigliardi-Qi M. Treatment of pruritus with topically applied opiate receptor antagonist. J. Am. Acad. Dermatol. 56: 979-988 (2007).
Bihl F, Salez L, Beaubier M, Torres D, Lariviere L, Laroche L, Benedetto A, Martel D, Lapointe JM, Ryffel B, Malo D. Overexpression of Toll-like receptor 4 amplifies the host response to lipopolysaccharide and provides a survival advantage in transgenic mice. J. Immunol. 170: 6141-6150 (2003). *
Bijl M, Reefman E, Horst G, Limburg PC, Kallenberg CG. Reduced uptake of apoptotic cells by macrophages in systemic lupus erythematosus (SLE): correlates with decreased serum levels of complement. Ann. Rheum. Dis. 65: 57-63 (2006). *
Bikle D, Teichert A, Hawker N, Xie Z, Oda Y. Sequential regulation of keratinocyte differentiation by 1,25(OH)(2)D(3), VDR, and its coregulators. J. Steroid Biochem. Mol. Biol. 103: 396-404 (2007).
Bikle DD, Elalieh H, Chang S, Xie Z, Sundberg JP. Development and progression of alopecia in the vitamin D receptor null mouse. J. Cell. Physiol. 207: 340-353 (2006). *
Bilate AM, Salemi VM, Ramires FJ, de Brito T, Russo M, Fonseca SG, Fae KC, Martins DG, Silva AM, Mady C, Kalil J, Cunha-Neto E. TNF blockade aggravates experimental chronic Chagas disease cardiomyopathy. Microbes Infect. 9: 1104-1113 (2007). *
Bilban M, Haslinger P, Prast J, Klinglmuller F, Woelfel T, Haider S, Sachs A, Otterbein LE, Desoye G, Hiden U, Wagner O, Knofler M. Identification of novel trophoblast invasion-related genes: heme oxygenase-1 controls motility via PPARgamma. Endocrinology 150: 1000-1013 (2009). *
Bilitewski U. DNA microarrays: an introduction to the technology. Methods Mol. Biol. 509: 1-14 (2009).
Bility MT, Devlin-Durante MK, Blazanin N, Glick AB, Ward JM, Kang BH, Kennett MJ, Gonzalez FJ, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits chemically-induced skin tumorigenesis. Carcinogenesis 29: 2406-2414 (2008). *
Billaut-Laden I, Allorge D, Crunelle-Thibaut A, Rat E, Cauffiez C, Chevalier D, Houdret N, Lo-Guidice JM, Broly F. Evidence for a functional genetic polymorphism of the human thiosulfate sulfurtransferase (Rhodanese), a cyanide and H(2)S detoxification enzyme. Toxicology 225: 1-11 (2006). *
Billaut-Laden I, Rat E, Allorge D, Crunelle-Thibaut A, Cauffiez C, Chevalier D, Lo-Guidice JM, Broly F. Evidence for a functional genetic polymorphism of the human mercaptopyruvate sulfurtransferase (MPST), a cyanide detoxification enzyme. Toxicol. Lett. 165: 101-111 (2006).
Billerey-Larmonier C, Uno JK, Larmonier N, Midura AJ, Timmermann B, Ghishan FK, Kiela PR. Protective effects of dietary curcumin in mouse model of chemically induced colitis are strain dependent. Inflamm. Bowel Dis. 14: 780-793 (2008). *
Billiet L, Furman C, Larigauderie G, Copin C, Page S, Fruchart JC, Brand K, Rouis M. Enhanced VDUP-1 gene expression by PPARgamma agonist induces apoptosis in human macrophage. J. Cell. Physiol. 214: 183-191 (2008). *
Bilz S, Samuel V, Morino K, Savage D, Choi CS, Shulman GI. Activation of the farnesoid X receptor improves lipid metabolism in combined hyperlipidemic hamsters. Am. J. Physiol. Endocrinol. Metab. 290: E716-E722 (2006). *
Bingle CD, Craven CJ. PLUNC: a novel family of candidate host defence proteins expressed in the upper airways and nasopharynx. Hum. Mol. Genet. 11: 937-943 (2002). *
Bingle L, Barnes FA, Cross SS, Rassl D, Wallace WA, Campos MA, Bingle CD. Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis. Respir. Res. 8: 79 (2007). *
Binion DG, Kugathasan S, Dwinell MB. Molecular stratification of Crohn's disease by chemokine receptors: fractalkine receptor polymorphisms define a fibrostenosing ileal subgroup. Am. J. Gastroenterol. 101: 107-109 (2006). *
Bioley G, Guillaume P, Luescher I, Yeh A, Dupont B, Bhardwaj N, Mears G, Old LJ, Valmori D, Ayyoub M. HLA class I-associated immunodominance affects CTL responsiveness to an ESO recombinant protein tumor antigen vaccine. Clin. Cancer Res. 15: 299-306 (2009). *
Bionaz M, Baumrucker CR, Shirk E, Vanden Heuvel JP, Block E, Varga GA. Characterization of Madin-Darby bovine kidney cell line for peroxisome proliferator-activated receptors: temporal response and sensitivity to fatty acids. J. Dairy Sci. 91: 2808-2813 (2008).
Biondo M, Field J, Toh BH, Alderuccio F. Prednisolone promotes remission and gastric mucosal regeneration in experimental autoimmune gastritis. J. Pathol. 209: 384-391 (2006). *
Birch D, Knight GE, Boulos PB, Burnstock G. Analysis of innervation of human mesenteric vessels in non-inflamed and inflamed bowel - a confocal and functional study. Neurogastroenterol. Motil. 20: 660-670 (2008).
Birebent B, Lorho R, Lechartier H, de Guibert S, Alizadeh M, Vu N, Beauplet A, Robillard N, Semana G. Suppressive properties of human CD4(+)CD25(+) regulatory T cells are dependent on CTLA-4 expression. Eur. J. Immunol. 34: 3485-3496 (2004). *
Birkenkamp-Demtroder K, Olesen SH, Sorensen FB, Laurberg S, Laiho P, Aaltonen LA, Orntoft TF. Differential gene expression in colon cancer of the caecum versus the sigmoid and rectosigmoid. Gut 54: 374-384 (2005). *
Birmachu W, Gleason RM, Bulbulian BJ, Riter CL, Vasilakos JP, Lipson KE, Nikolsky Y. Transcriptional networks in plasmacytoid dendritic cells stimulated with synthetic TLR 7 agonists. BMC Immunol. 8: 26 (2007). *
Birnbaum G, Kotilinek L. Heat shock or stress proteins and their role as autoantigens in multiple sclerosis. Ann. N. Y. Acad. Sci. 835: 157-167 (1997). *
Birnbaum G, Kotilinek L. Immunity to heat shock proteins and neurological disorders of women. Infect. Dis. Obstet. Gynecol. 7: 39-48 (1999).
Biro T, Toth BI, Marincsak R, Dobrosi N, Geczy T, Paus R. TRP channels as novel players in the pathogenesis and therapy of itch. Biochim. Biophys. Acta 1772: 1004-1021 (2007). *
Birrell MA, Catley MC, Hardaker E, Wong S, Willson TM, McCluskie K, Leonard T, Farrow SN, Collins JL, Haj-Yahia S, Belvisi MG. Novel role for the liver X nuclear receptor in the suppression of lung inflammatory responses. J. Biol. Chem. 282: 31882-31890 (2007). *
Bises G, Bajna E, Manhardt T, Gerdenitsch W, Kallay E, Cross HS. Gender-specific modulation of markers for premalignancy by nutritional soy and calcium in the mouse colon. J. Nutr. 137: 211S-215S (2007). *
Bisgaard HC, Holmskov U, Santoni-Rugiu E, Nagy P, Nielsen O, Ott P, Hage E, Dalhoff K, Rasmussen LJ, Tygstrup N. Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor 1. Am. J. Pathol. 161: 1187-1198 (2002). *
Bishnupuri KS, Luo Q, Murmu N, Houchen CW, Anant S, Dieckgraefe BK. Reg IV activates the epidermal growth factor receptor/Akt/AP-1 signaling pathway in colon adenocarcinomas. Gastroenterology 130: 137-149 (2006). *
Bisping G, Lugering N, Lutke-Brintrup S, Pauels HG, Schurmann G, Domschke W, Kucharzik T. Patients with inflammatory bowel disease (IBD) reveal increased induction capacity of intracellular interferon-gamma (IFN-gamma) in peripheral CD8+ lymphocytes co-cultured with intestinal epithelial cells. Clin. Exp. Immunol. 123: 15-22 (2001). *
Bissig KD, Le TT, Woods NB, Verma IM. Repopulation of adult and neonatal mice with human hepatocytes: a chimeric animal model. Proc. Natl. Acad. Sci. U.S.A. 104: 20507-20511 (2007). *
Bissonnette M, Khare S, von Lintig FC, Wali RK, Nguyen L, Zhang Y, Hart J, Skarosi S, Varki N, Boss GR, Brasitus TA. Mutational and nonmutational activation of p21ras in rat colonic azoxymethane-induced tumors: effects on mitogen-activated protein kinase, cyclooxygenase-2, and cyclin D1. Cancer Res. 60: 4602-4609 (2000). *
Bissonnette RP, Brunner T, Lazarchik SB, Yoo NJ, Boehm MF, Green DR, Heyman RA. 9-cis Retinoic acid inhibition of activation-induced apoptosis is mediated via regulation of Fas ligand and requires retinoic acid receptor and retinoid X receptor activation. Mol. Cell. Biol. 15: 5576-5585 (1995). *
Bister V, Makitalo L, Jeskanen L, Saarialho-Kere U. Expression of MMP-9, MMP-10 and TNF-alpha and lack of epithelial MMP-1 and MMP-26 characterize pyoderma gangrenosum. J. Cutan. Pathol. 34: 889-898 (2007). *
Biswas PS, Pedicord V, Ploss A, Menet E, Leiner I, Pamer EG. Pathogen-specific CD8 T cell responses are directly inhibited by IL-10. J. Immunol. 179: 4520-4528 (2007). *
Bittencourt PL, Palacios SA, Cancado EL, Porta G, Carrilho FJ, Laudanna AA, Kalil J, Goldberg AC. Cytotoxic T lymphocyte antigen-4 gene polymorphisms do not confer susceptibility to autoimmune hepatitis types 1 and 2 in Brazil. Am. J. Gastroenterol. 98: 1616-1620 (2003). *
Bitzer M, von Gersdorff G, Liang D, Dominguez-Rosales A, Beg AA, Rojkind M, Bottinger EP. A mechanism of suppression of TGF-beta/SMAD signaling by NF-kappa B/RelA. Genes Dev. 14: 187-197 (2000). *
Bjerkeli V, Halvorsen B, Damas JK, Nordoy I, Yndestad A, Aukrust P, Froland SS. Expression of matrix metalloproteinases in patients with Wegener's granulomatosis. Ann. Rheum. Dis. 63: 1659-1663 (2004). *
Bjornsson E, Chapman RW. Sclerosing cholangitis. Curr. Opin. Gastroenterol. 19: 270-275 (2003).
Bjorses P, Halonen M, Palvimo JJ, Kolmer M, Aaltonen J, Ellonen P, Perheentupa J, Ulmanen I, Peltonen L. Mutations in the AIRE gene: effects on subcellular location and transactivation function of the autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy protein. Am. J. Hum. Genet. 66: 378-392 (2000). *
Bjorses P, Pelto-Huikko M, Kaukonen J, Aaltonen J, Peltonen L, Ulmanen I. Localization of the APECED protein in distinct nuclear structures. Hum. Mol. Genet. 8: 259-266 (1999). *
Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. J. Hepatol. 40: 942-951 (2004). *
Black JA, Liu S, Waxman SG. Sodium channel activity modulates multiple functions in microglia. Glia Dec 29 [Epub ahead of print] (2008).
Black JA, Newcombe J, Trapp BD, Waxman SG. Sodium channel expression within chronic multiple sclerosis plaques. J. Neuropathol. Exp. Neurol. 66: 828-837 (2007).
Blackledge NP, Carter EJ, Evans JR, Lawson V, Rowntree RK, Harris A. CTCF mediates insulator function at the CFTR locus. Biochem. J. 408: 267-275 (2007). *
Blackledge NP, Ott CJ, Gillen AE, Harris A. An insulator element 3' to the CFTR gene binds CTCF and reveals an active chromatin hub in primary cells. Nucleic Acids Res. 37: 1086-1094 (2009). *
Blackwell JM. Structure and function of the natural-resistance-associated macrophage protein (Nramp1), a candidate protein for infectious and autoimmune disease susceptibility. Mol. Med. Today 2: 205-211 (1996).
Blackwell JM, Searle S. Genetic regulation of macrophage activation: understanding the function of Nramp1 (=Ity/Lsh/Bcg). Immunol. Lett. 65: 73-80 (1999).
Blackwell K, Zhang L, Thomas GS, Sun S, Nakano H, Habelhah H. TRAF2 phosphorylation modulates TNFalpha-induced gene expression and cell resistance to apoptosis. Mol. Cell. Biol. 29: 303-314 (2009). *
Blair SA, Kane SV, Clayburgh DR, Turner JR. Epithelial myosin light chain kinase expression and activity are upregulated in inflammatory bowel disease. Lab. Invest. 86: 191-201 (2006). *
Blais M, Seidman EG, Asselin C. Dual effect of butyrate on IL-1beta-mediated intestinal epithelial cell inflammatory response. DNA Cell Biol. 26: 133-147 (2007).
Blanchard C, Durual S, Estienne M, Emami S, Vasseur S, Cuber JC. Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated by interleukin-4 and interleukin-13 via the signal transducer and activator of transcription 6. Int. J. Biochem. Cell. Biol. 37: 2559-2573 (2005). *
Blanchard C, Mingler MK, Vicario M, Abonia JP, Wu YY, Lu TX, Collins MH, Putnam PE, Wells SI, Rothenberg ME. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. J. Allergy Clin. Immunol. 120: 1292-1300 (2007). *
Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116: 536-547 (2006). *
Blanchard RK, Cousins RJ. Regulation of intestinal gene expression by dietary zinc: induction of uroguanylin mRNA by zinc deficiency. J. Nutr. 130: 1393S-1398S (2000). *
Blanchard TG, Drakes ML, Czinn SJ. Helicobacter infection: pathogenesis. Curr. Opin. Gastroenterol. 20: 10-15 (2004).
Blanco P, Pitard V, Viallard JF, Taupin JL, Pellegrin JL, Moreau JF. Increase in activated CD8+ T lymphocytes expressing perforin and granzyme B correlates with disease activity in patients with systemic lupus erythematosus. Arthritis Rheum. 52: 201-211 (2005). *
Blank C, Gajewski TF, Mackensen A. Interaction of PD-L1 on tumor cells with PD-1 on tumor-specific T cells as a mechanism of immune evasion: implications for tumor immunotherapy. Cancer Immunol. Immunother. 54: 307-314 (2005). *
Blank M, Shoenfeld Y. The story of the 16/6 idiotype and systemic lupus erythematosus. Isr. Med. Assoc. J. 10: 37-39 (2008). *
Blank MC, Stefanescu RN, Masuda E, Marti F, King PD, Redecha PB, Wurzburger RJ, Peterson MG, Tanaka S, Pricop L. Decreased transcription of the human FCGR2B gene mediated by the -343 G/C promoter polymorphism and association with systemic lupus erythematosus. Hum. Genet. 117: 220-227 (2005). *
Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes 54: 1233-1237 (2005). *
Blanquart C, Barbier O, Fruchart JC, Staels B, Glineur C. Peroxisome proliferator-activated receptor alpha (PPARalpha ) turnover by the ubiquitin-proteasome system controls the ligand-induced expression level of its target genes. J. Biol. Chem. 277: 37254-37259 (2002). *
Blaschke F, Takata Y, Caglayan E, Collins A, Tontonoz P, Hsueh WA, Tangirala RK. A nuclear receptor corepressor-dependent pathway mediates suppression of cytokine-induced C-reactive protein gene expression by liver X receptor. Circ. Res. 99: e88-e99 (2006). *
Blechacz B, Splinter PL, Greiner S, Myers R, Peng KW, Federspiel MJ, Russell SJ, LaRusso NF. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology 44: 1465-1477 (2006). *
Blechschmidt K, Schweiger M, Wertz K, Poulson R, Christensen HM, Rosenthal A, Lehrach H, Yaspo ML. The mouse Aire gene: comparative genomic sequencing, gene organization, and expression. Genome Res. 9: 158-166 (1999). *
Bleiber G, May M, Suarez C, Martinez R, Marzolini C, Egger M, Telenti A; Swiss HIV Cohort Study. MDR1 genetic polymorphism does not modify either cell permissiveness to HIV-1 or disease progression before treatment. J. Infect. Dis. 189: 583-586 (2004). *
Bleich D, Chen S, Zipser B, Sun D, Funk CD, Nadler JL. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice. J. Clin. Invest. 103: 1431-1436 (1999). *
Blenman KR, Duan B, Xu Z, Wan S, Atkinson MA, Flotte TR, Croker BP, Morel L. IL-10 regulation of lupus in the NZM2410 murine model. Lab. Invest. 86: 1136-1148 (2006). *
Bloch DB, de la Monte SM, Guigaouri P, Filippov A, Bloch KD. Identification and characterization of a leukocyte-specific component of the nuclear body. J. Biol. Chem. 271: 29198-29204 (1996). *
Blokzijl H, Vander Borght S, Bok LI, Libbrecht L, Geuken M, van den Heuvel FA, Dijkstra G, Roskams TA, Moshage H, Jansen PL, Faber KN. Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels. Inflamm. Bowel Dis. 13: 710-720 (2007). *
Bloomer J, Wang Y, Singhal A, Risheg H. Molecular studies of liver disease in erythropoietic protoporphyria. J. Clin. Gastroenterol. 39: S167-S175 (2005).
Bloquel C, Bessis N, Boissier MC, Scherman D, Bigey P. Gene therapy of collagen-induced arthritis by electrotransfer of human tumor necrosis factor-alpha soluble receptor I variants. Hum. Gene Ther. 15: 189-201 (2004). *
Bluestone JA. A balanced attack. The Scientist May, 2007 (http://www.the-scientist.com/2007/05/01/s32/1/ ) (2007).
Blum A, Setiawan T, Hang L, Stoyanoff K, Weinstock JV. Interleukin-12 (IL-12) and IL23 induction of substance P synthesis in murine T cells and macrophages is subject to IL10 and TGFbeta regulation. Infect. Immun. 76: 3651-3656 (2008). *
Blum HE. Gene therapy for liver diseases: experimental strategies. Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 44-45 (2006). *
Blum HE. Hepatocellular carcinoma: therapy and prevention. World J. Gastroenterol. 11: 7391-7400 (2005). *
Blum HE. Treatment of hepatocellular carcinoma. Best Pract. Res. Clin. Gastroenterol. 19: 129-145 (2005).
Blum R, Gupta R, Burger PE, Ontiveros CS, Salm SN, Xiong X, Kamb A, Wesche H, Marshall L, Cutler G, Wang X, Zavadil J, Moscatelli D, Wilson EL. Molecular signatures of prostate stem cells reveal novel signaling pathways and provide insights into prostate cancer. PLoS ONE 4: e5722 (2009). *
Blumberg B, Sabbagh W Jr, Juguilon H, Bolado J Jr, van Meter CM, Ong ES, Evans RM. SXR, a novel steroid and xenobiotic-sensing nuclear receptor. Genes Dev. 12: 3195-3205 (1998). *
Blumberg JM, Tzameli I, Astapova I, Lam FS, Flier JS, Hollenberg AN. Complex role of the vitamin D receptor and its ligand in adipogenesis in 3T3-L1 cells. J. Biol. Chem. 281: 11205-11213 (2006). *
Blumerman SL, Herzig CT, Wang F, Coussens PM, Baldwin CL. Comparison of gene expression by co-cultured WC1(+) gammadelta and CD4(+) alphabeta T cells exhibiting a recall response to bacterial antigen. Mol. Immunol. 44: 2033-2045 (2007). *
Bluthner M, Schafer C, Schneider C, Bautz FA. Identification of major linear epitopes on the sp100 nuclear PBC autoantigen by the gene-fragment phage-display technology. Autoimmunity 29: 33-42 (1999).
Blyth K, Vaillant F, Hanlon L, Mackay N, Bell M, Jenkins A, Neil JC, Cameron ER. Runx2 and MYC collaborate in lymphoma development by suppressing apoptotic and growth arrest pathways in vivo. Cancer Res. 66: 2195-2201 (2006). *
Bo X, Broome U, Remberger M, Sumitran-Holgersson S. Tumour necrosis factor alpha impairs function of liver derived T lymphocytes and natural killer cells in patients with primary sclerosing cholangitis. Gut 49: 131-141 (2001). *
Boadu E, Choi HY, Lee DW, Waddington EI, Chan T, Asztalos B, Vance JE, Chan A, Castro G, Francis GA. Correction of apolipoprotein A-I-mediated lipid efflux and HDL particle formation in human Niemann-Pick type C disease fibroblasts. J. Biol. Chem. 281: 37081-37090 (2006). *
Bobacz K, Sunk IG, Hofstaetter JG, Amoyo L, Toma CD, Akira S, Weichhart T, Saemann M, Smolen JS. Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of Toll-like receptor 4 and antagonized by bone morphogenetic protein 7. Arthritis Rheum. 56: 1880-1893 (2007). *
Boberg J, Metzdorff S, Wortziger R, Axelstad M, Brokken L, Vinggaard AM, Dalgaard M, Nellemann C. Impact of diisobutyl phthalate and other PPAR agonists on steroidogenesis and plasma insulin and leptin levels in fetal rats. Toxicology 250: 75-81 (2008). *
Boberg KM, Lundin KE, Schrumpf E. Etiology and pathogenesis in primary sclerosing cholangitis. Scand. J. Gastroenterol. Suppl. 204: 47-58 (1994).
Boberg KM, Schrumpf E. Diagnosis and treatment of cholangiocarcinoma. Curr. Gastroenterol. Rep. 6: 52-59 (2004).
Bocca C, Bozzo F, Francica S, Colombatto S, Miglietta A. Involvement of PPARgamma and E-cadherin/beta-catenin pathway in the antiproliferative effect of conjugated linoleic acid in MCF-7 cells. Int. J. Cancer 121: 248-256 (2007). *
Bocca C, Bozzo F, Martinasso G, Canuto RA, Miglietta A. Involvement of PPARalpha in the growth inhibitory effect of arachidonic acid on breast cancer cells. Br. J. Nutr. 100: 739-750 (2008). *
Bocher V, Pineda-Torra I, Fruchart JC, Staels B. PPARs: transcription factors controlling lipid and lipoprotein metabolism. Ann. N. Y. Acad. Sci. 967: 7-18 (2002). *
Bochkis IM, Rubins NE, White P, Furth EE, Friedman JR, Kaestner KH. Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat. Med. 14: 828-836 (2008). *
Bochkis IM, Schug J, Rubins NE, Chopra AR, O'Malley BW, Kaestner KH. Foxa2-dependent hepatic gene regulatory networks depend on physiological state. Physiol. Genomics May 5 [Epub ahead of print] (2009). *
Bock C, Lengauer T. Computational epigenetics. Bioinformatics 24: 1-10 (2008). *
Bock HH, Lammert F. Nuclear xeno-sensors as receptors for cholestatic bile acids: the second line of defense. Hepatology 35: 232-234 (2002). *
Bock KW, Kohle C. UDP-glucuronosyltransferase 1A6: structural, functional, and regulatory aspects. Methods Enzymol. 400: 57-75 (2005).
Bockelmann R, Horn T, Gollnick H, Bonnekoh B. Interferon-gamma-dependent in vitro model for the putative keratin 17 autoimmune loop in psoriasis: exploration of pharmaco- and gene-therapeutic effects. Skin Pharmacol. Physiol. 18: 42-54 (2005).
Bodaghi B, Rao N. Relevance of animal models to human uveitis. Ophthalmic Res. 40: 200-202 (2008).
Bode KA, Schroder K, Hume DA, Ravasi T, Heeg K, Sweet MJ, Dalpke AH. Histone deacetylase inhibitors decrease Toll-like receptor-mediated activation of proinflammatory gene expression by impairing transcription factor recruitment. Immunology 122: 596-606 (2007). *
Boden G, Zhang M. Recent findings concerning thiazolidinediones in the treatment of diabetes. Expert Opin. Investig. Drugs 15: 243-250 (2006).
Bodger K, Halfvarson J, Dodson A, Campbell F, Wilson S, Lee R, Lindberg E, Jarnerot G, Tysk C, Rhodes J. Altered colonic glycoprotein expression in unaffected monozygotic twins of inflammatory bowel disease patients. Gut 55: 973-977 (2006). *
Bodin K. Role of CYP3A4 as a cholesterol and bile acid metabolizing enzyme. Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 25. June 18-19 (2004). *
Boettler T, Panther E, Bengsch B, Nazarova N, Spangenberg HC, Blum HE, Thimme R. Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection. J. Virol. 80: 3532-3540 (2006). *
Bogazzi F, Bartalena L, Brogioni S, Burelli A, Grasso L, Dell'Unto E, Manetti L, Martino E. L-Thyroxine directly affects expression of thyroid hormone-sensitive genes: regulatory effect of RXRbeta. Mol. Cell. Endocrinol. 134: 23-31 (1997).
Bogert PT, LaRusso NF. Cholangiocyte biology. Curr. Opin. Gastroenterol. 23: 299-305 (2007).
Bogoch Y, Linial M. Coordinated expression of cytoskeleton regulating genes in the accelerated neurite outgrowth of P19 embryonic carcinoma cells. Exp. Cell Res. 314: 677-690 (2008). *
Bogoevska V, Horst A, Klampe B, Lucka L, Wagener C, Nollau P. CEACAM1, an adhesion molecule of human granulocytes, is fucosylated by fucosyltransferase IX and interacts with DC-SIGN of dendritic cells via LewisX residues. Glycobiology 16: 197-209 (2006). *
Bogunia-Kubik K, Jaskula E, Lange A. The presence of functional CCR5 and EBV reactivation after allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant. 40: 145-150 (2007).
Bogunovic M, Dave SH, Tilstra JS, Chang DT, Harpaz N, Xiong H, Mayer LF, Plevy SE. Enteroendocrine cells express functional Toll-like receptors. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1770-G1783 (2007). *
Bohan A, Boyer JL. Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions. Semin. Liver Dis. 22: 123-136 (2002).
Bohgaki T, Amasaki Y, Nishimura N, Bohgaki M, Yamashita Y, Nishio M, Sawada KI, Jodo S, Atsumi T, Koike T. Up regulated expression of tumour necrosis factor alpha converting enzyme in peripheral monocytes of patients with early systemic sclerosis. Ann. Rheum. Dis. 64: 1165-1173 (2005). *
Bohlken A, Cheung BB, Bell JL, Koach J, Smith S, Sekyere E, Thomas W, Norris M, Haber M, Lovejoy DB, Richardson DR, Marshall GM. ATP7A is a novel target of retinoic acid receptor beta2 in neuroblastoma cells. Br. J. Cancer 100: 96-105 (2009). *
Bohn E, Bechtold O, Zahir N, Frick JS, Reimann J, Jilge B, Autenrieth IB. Host gene expression in the colon of gnotobiotic interleukin-2-deficient mice colonized with commensal colitogenic or noncolitogenic bacterial strains: common patterns and bacteria strain specific signatures. Inflamm. Bowel Dis. 12: 853-862 (2006). *
Bohn G, Allroth A, Brandes G, Thiel J, Glocker E, Schaffer AA, Rathinam C, Taub N, Teis D, Zeidler C, Dewey RA, Geffers R, Buer J, Huber LA, Welte K, Grimbacher B, Klein C. A novel human primary immunodeficiency syndrome caused by deficiency of the endosomal adaptor protein p14. Nat. Med. 13: 38-45 (2007). *
Bohren KM, Nadkarni V, Song JH, Gabbay KH, Owerbach D. A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J. Biol. Chem. 279: 27233-27238 (2004). *
Bois-Joyeux B, Chauvet C, Nacer-Cherif H, Bergeret W, Mazure N, Giguere V, Laudet V, Danan JL. Modulation of the far-upstream enhancer of the rat alpha-fetoprotein gene by members of the ROR alpha, Rev-erb alpha, and Rev-erb beta groups of monomeric orphan nuclear receptors. DNA Cell Biol. 19: 589-599 (2000).
Boitier E, Gautier JC, Roberts R. Advances in understanding the regulation of apoptosis and mitosis by peroxisome-proliferator activated receptors in pre-clinical models: relevance for human health and disease. Comp. Hepatol. 2: 3 (2003). *
Bolland D, Corcoran A. Somatic hypermutation is a matter of choice. Nat. Immunol. 8: 677-679 (2007). *
Bolstad AI, Jonsson R. Gene therapeutics in Sjogren's syndrome. Expert Opin. Biol. Ther. 5: 763-772 (2005).
Bolt HM. Rifampicin, a keystone inducer of drug metabolism: from Herbert Remmer's pioneering ideas to modern concepts. Drug Metab. Rev. 36: 497-509 (2004).
Bombail V, Taylor K, Gibson GG, Plant N. Role of Sp1, C/EBPalpha, HNF3, and PXR in the basal- and xenobiotic-mediated regulation of the CYP3A4 gene. Drug Metab. Dispos. 32: 525-535 (2004). *
Bommareddy A, Arasada BL, Mathees DP, Dwivedi C. Chemopreventive effects of dietary flaxseed on colon tumor development. Nutr. Cancer 54: 216-222 (2006). *
Bommareddy A, Zhang X, Schrader D, Kaushik RS, Zeman D, Matthees DP, Dwivedi C. Effects of dietary flaxseed on intestinal tumorigenesis in apc(min) mouse. Nutr. Cancer 61: 276-283 (2009).
Bommireddy R, Doetschman T. TGFbeta1 and T(reg) cells: alliance for tolerance. Trends Mol. Med. 13: 492-501 (2007). *
Bommireddy R, Pathak LJ, Martin J, Ormsby I, Engle SJ, Boivin GP, Babcock GF, Eriksson AU, Singh RR, Doetschman T. Self-antigen recognition by TGFbeta1-deficient T cells causes their activation and systemic inflammation. Lab. Invest. 86: 1008-1019 (2006). *
Boncoeur E, Criq VS, Bonvin E, Roque T, Henrion-Caude A, Gruenert DC, Clement A, Jacquot J, Tabary O. Oxidative stress induces extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase in cystic fibrosis lung epithelial cells: potential mechanism for excessive IL-8 expression. Int. J. Biochem. Cell Biol. 40: 432-446 (2008). *
Bondeva T, Roger T, Wolf G. Differential regulation of Toll-like receptor 4 gene expression in renal cells by angiotensin II: dependency on AP1 and PU.1 transcriptional sites. Am. J. Nephrol. 27: 308-314 (2007).
Bonelli M, Savitskaya A, Steiner CW, Rath E, Smolen JS, Scheinecker C. Phenotypic and functional analysis of CD4+CD25-Foxp3+ T cells in patients with systemic lupus erythematosus. J. Immunol. 182: 1689-1695 (2009).
Bonelli M, Savitskaya A, von Dalwigk K, Steiner CW, Aletaha D, Smolen JS, Scheinecker C. Quantitative and qualitative deficiencies of regulatory T cells in patients with systemic lupus erythematosus (SLE). Int. Immunol. 20: 861-868 (2008).
Bonelli M, von Dalwigk K, Savitskaya A, Smolen JS, Scheinecker C. Foxp3 expression in CD4+ T cells of patients with systemic lupus erythematosus: a comparative phenotypic analysis. Ann. Rheum. Dis. 67: 664-671 (2008).
Bonet ML, Ribot J, Felipe F, Palou A. Vitamin A and the regulation of fat reserves. Cell. Mol. Life Sci. 60: 1311-1321 (2003).
Bonfield TL, Barna BP, John N, Malur A, Culver DA, Kavuru MS, Thomassen MJ. Suppression of activin A in autoimmune lung disease associated with anti-GM-CSF. J. Autoimmun. 26: 37-41 (2006).
Bonfield TL, Swaisgood CM, Barna BP, Farver CF, Kavuru MS, Thomassen MJ. Elevated gelatinase activity in pulmonary alveolar proteinosis: role of macrophage-colony stimulating factor. J. Leukoc. Biol. 79: 133-139 (2006). *
Bonfield TL, Thomassen MJ, Farver CF, Abraham S, Koloze MT, Zhang X, Mosser DM, Culver DA. Peroxisome proliferator-activated receptor-gamma regulates the expression of alveolar macrophage macrophage colony-stimulating factor. J. Immunol. 181: 235-242 (2008).
Bonhomme-Faivre L, Devocelle A, Saliba F, Chatled S, Maccario J, Farinotti R, Picard V. MDR-1 C3435T polymorphism influences cyclosporine A dose requirement in liver-transplant recipients. Transplantation 78: 21-25 (2004).
Bonif M, Meuwis MA, Close P, Benoit V, Heyninck K, Chapelle JP, Bours V, Merville MP, Piette J, Beyaert R, Chariot A. TNFalpha- and IKKbeta-mediated TANK/I-TRAF phosphorylation: implications for interaction with NEMO/IKKgamma and NF-kappaB activation. Biochem. J. 394: 593-603 (2006). *
Boniface K, Bernard FX, Garcia M, Gurney AL, Lecron JC, Morel F. IL-22 inhibits epidermal differentiation and induces proinflammatory gene expression and migration of human keratinocytes. J. Immunol. 174: 3695-3702 (2005). *
Boniface K, Blom B, Liu YJ, de Waal Malefyt R. From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited. Immunol. Rev. 226: 132-146 (2008). *
Boniface K, Diveu C, Morel F, Pedretti N, Froger J, Ravon E, Garcia M, Venereau E, Preisser L, Guignouard E, Guillet G, Dagregorio G, Pene J, Moles JP, Yssel H, Chevalier S, Bernard FX, Gascan H, Lecron JC. Oncostatin M secreted by skin infiltrating T lymphocytes is a potent keratinocyte activator involved in skin inflammation. J. Immunol. 178: 4615-4622 (2007). *
Boniface K, Lecron JC, Bernard FX, Dagregorio G, Guillet G, Nau F, Morel F. Keratinocytes as targets for interleukin-10-related cytokines: a putative role in the pathogenesis of psoriasis. Eur. Cytokine Netw. 16: 309-319 (2005).
Bonin S, Pascolo L, Croce LS, Stanta G, Tiribelli C. Gene expression of ABC proteins in hepatocellular carcinoma, perineoplastic tissue, and liver diseases. Mol. Med. 8: 318-325 (2002). *
Boniotto M, Radillo O, Braida L, Pirulli D, Citta A, Not T, Amoroso A, Crovella S. Detection of MBL-2 gene expression in intestinal biopsies of celiac patients by in situ reverse transcription polymerase chain reaction. Eur. J. Histochem. 47: 177-180 (2003).
Bonnefont-Rebeix C, Marchal T, Bernaud J, Pin JJ, Leroux C, Lebecque S, Chabanne L, Rigal D. Toll-like receptor 3 (TLR3): a new marker of canine monocytes-derived dendritic cells (cMo-DC). Vet. Immunol. Immunopathol. 118: 134-139 (2007). *
Bonnekoh B, Pommer AJ, Bockelmann R, Hofmeister H, Philipsen L, Gollnick H. Topo-proteomic in situ analysis of psoriatic plaque under efalizumab treatment. Skin Pharmacol. Physiol. 20: 237-252 (2007).
Bonnet E, Touyarot K, Alfos S, Pallet V, Higueret P, Abrous DN. Retinoic acid restores adult hippocampal neurogenesis and reverses spatial memory deficit in vitamin A deprived rats. PLoS ONE 3: e3487 (2008). *
Boone DL, Turer EE, Lee EG, Ahmad RC, Wheeler MT, Tsui C, Hurley P, Chien M, Chai S, Hitotsumatsu O, McNally E, Pickart C, Ma A. The ubiquitin-modifying enzyme A20 is required for termination of Toll-like receptor responses. Nat. Immunol. 5: 1052-1060 (2004). *
Boonsaen T, Rojvirat P, Surinya KH, Wallace JC, Jitrapakdee S. Transcriptional regulation of the distal promoter of the rat pyruvate carboxylase gene by hepatocyte nuclear factor 3beta/Foxa2 and upstream stimulatory factors in insulinoma cells. Biochem. J. 405: 359-367 (2007). *
Booth DR, Arthur AT, Teutsch SM, Bye C, Rubio J, Armati PJ, Pollard JD, Heard RN, Stewart GJ; The Southern MS Genetics Consortium. Gene expression and genotyping studies implicate the interleukin 7 receptor in the pathogenesis of primary progressive multiple sclerosis. J. Mol. Med. 83: 822-830 (2005). *
Booth G, Newham P, Barlow R, Raines S, Zheng B, Han S. Gene expression profiles at different stages of collagen-induced arthritis. Autoimmunity 41: 512-521 (2008).
Boothby M. The calculus of integrating differentiation: timing control of T-bet. Immunity 30: 666-668 (2009). *
Booty MG, Chae JJ, Masters SL, Remmers EF, Barham B, Le JM, Barron KS, Holland SM, Kastner DL, Aksentijevich I. Familial Mediterranean fever with a single MEFV mutation: where is the second hit? Arthritis Rheum. 60: 1851-1861 (2009).
Boquoi A, Jover R, Chen T, Pennings M, Enders G. Transgenic expression of VEGF in intestinal epithelium drives mesenchymal cell interactions and epithelial neoplasia. Gastroenterology 136: 596-606.e4 (2009). *
Boraska V, Torlak V, Skrabic V, Kacic Z, Jaksic J, Stipancic G, Spehar A, Markotic A, Zemunik T. Glycosyltransferase B4GALNT1 and type 1 diabetes in Croatian population. Clin. Biochem. 42: 819-822 (2009). *
Borchers MT, Wesselkamper SC, Curull V, Ramirez-Sarmiento A, Sanchez-Font A, Garcia-Aymerich J, Coronell C, Lloreta J, Agusti AG, Gea J, Howington JA, Reed MF, Starnes SL, Harris NL, Vitucci M, Eppert BL, Motz GT, Fogel K, McGraw DW, Tichelaar JW, et al. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease. J. Clin. Invest. pii: 34462 (2009). *
Bordoni A, Di Nunzio M, Danesi F, Biagi PL. Polyunsaturated fatty acids: from diet to binding to PPARs and other nuclear receptors. Genes & Nutrition 1: 95-106 (2006). *
Bordoni A, Di Nunzio M, Danesi F, Biagi PL. Polyunsaturated fatty acids: from diet to binding to PPARs and other nuclear receptors. Genes Nutr. 1: 95-106 (2006).
Bordoni V, Alonzi T, Zanetta L, Khouri D, Conti A, Corazzari M, Bertolini F, Antoniotti P, Pisani G, Tognoli F, Dejana E, Tripodi M. Hepatocyte-conditioned medium sustains endothelial differentiation of human hematopoietic-endothelial progenitors. Hepatology 45: 1218-1228 (2007). *
Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily. Biochem. Biophys. Res. Commun. 357: 977-983 (2007). *
Borge BA, Kalland KH, Olsen S, Bletsa A, Berggreen E, Wiig H. Cytokines are produced locally by myocytes in rat skeletal muscle during endotoxemia. Am. J. Physiol. Heart Circ. Physiol. 296: H735-H744 (2009). *
Borghaei RC, Gorski G, Javadi M, Chambers M. NF-kappaB and ZBP-89 regulate MMP-3 expression via a polymorphic site in the promoter. Biochem. Biophys. Res. Commun. 382: 269-273 (2009). *
Borghi A, Fogli E, Stignani M, Melchiorri L, Altieri E, Baricordi O, Rizzo R, Virgili A. Soluble human leukocyte antigen-G and interleukin-10 levels in plasma of psoriatic patients: preliminary study on a possible correlation between generalized immune status, treatments and disease. Arch. Dermatol. Res. 300: 551-559 (2008). *
Borgmann S, Haubitz M. Genetic impact of pathogenesis and prognosis of ANCA-associated vasculitides. Clin. Exp. Rheumatol. 22 (6 Suppl. 36): S79-S86 (2004).
Borgogni E, Sarchielli E, Sottili M, Santarlasci V, Cosmi L, Gelmini S, Lombardi A, Cantini G, Perigli G, Luconi M, Vannelli GB, Annunziato F, Adorini L, Serio M, Crescioli C. Elocalcitol inhibits inflammatory responses in human thyroid cells and T cells. Endocrinology 149: 3626-3634 (2008). *
Borland MG, Foreman JE, Girroir EE, Zolfaghari R, Sharma AK, Amin SM, Gonzalez FJ, Ross AC, Peters JM. Ligand activation of peroxisome proliferator-activated receptor-beta/delta (PPARbeta/delta) inhibits cell proliferation in human HaCaT keratinocytes. Mol. Pharmacol. 74: 1429-1442 (2008). *
Borm ME, He J, Kelsall B, Pena AS, Strober W, Bouma G. A major quantitative trait locus on mouse chromosome 3 is involved in disease susceptibility in different colitis models. Gastroenterology 128: 74-85 (2005). *
Borregaard N, Sorensen OE, Theilgaard-Monch K. Neutrophil granules: a library of innate immunity proteins. Trends Immunol. 28: 340-345 (2007). *
Borrego F, Kabat J, Kim DK, Lieto L, Maasho K, Pena J, Solana R, Coligan JE. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Mol. Immunol. 38: 637-660 (2002). *
Borruel N, Carol M, Casellas F, Antol�n M, de Lara F, Esp�n E, Naval J, Guarner F, Malagelada JR. Increased mucosal tumour necrosis factor alpha production in Crohn's disease can be downregulated ex vivo by probiotic bacteria. Gut 51: 659-664 (2002). *
Borst P, Evers R, Kool M, Wijnholds J. A family of drug transporters: the multidrug resistance-associated proteins. J. Natl. Cancer Inst. 92: 1295-1302 (2000). *
Borthwick F, Taylor JM, Bartholomew C, Graham A. Differential regulation of the STARD1 subfamily of START lipid trafficking proteins in human macrophages. FEBS Lett. 583: 1147-1153 (2009). *
Borysiewicz E, Fil D, Konat GW. Rho proteins are negative regulators of TLR2, TLR3, and TLR4 signaling in astrocytes. J. Neurosci. Res. 87: 1565-1572 (2009).
Bos CL, Diks SH, Hardwick JC, Walburg KV, Peppelenbosch MP, Richel DJ. Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity. Carcinogenesis 27: 2371-2382 (2006). *
Bos CL, van Baarsen LG, Timmer TC, Overbeek MJ, Basoski NM, Rustenburg F, Baggen JM, Thiesen HJ, Dijkmans BA, van der Pouw Kraan TC, Voskuyl AE, Verweij CL. Molecular subtypes of systemic sclerosis in association with anti-centromere antibodies and digital ulcers. Genes Immun. 10: 210-218 (2009).
Bosch TM, Deenen M, Pruntel R, Smits PH, Schellens JH, Beijnen JH, Meijerman I. Screening for polymorphisms in the PXR gene in a Dutch population. Eur. J. Clin. Pharmacol. 62: 395-399 (2006). *
Bose JS, Gangan V, Jain SK, Manna SK. Novel caffeic acid ester derivative induces apoptosis by expressing Fasl and downregulating NF-kappaB: potentiation of cell death mediated by chemotherapeutic agents. J. Cell. Physiol. 218: 653-662 (2008). *
Bosello S, Pers JO, Rochas C, Devauchelle V, De Santis M, Daridon C, Saraux A, Ferraccioli GF, Youinou P. BAFF and rheumatic autoimmune disorders: implications for disease management and therapy. Int. J. Immunopathol. Pharmacol. 20: 1-8 (2007).
Bosisio D, Vulcano M, Del Prete A, Sironi M, Salvi V, Salogni L, Riboldi E, Leoni F, Dinarello CA, Girolomoni G, Sozzani S. Blocking TH17-polarizing cytokines by histone deacetylase inhibitors in vitro and in vivo. J. Leukoc. Biol. 84: 1540-1548 (2008). *
Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, Lindhout D, Tytgat GN, Jansen PL, Oude Elferink RP, et al. The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N. Engl. J. Med. 333: 1171-1175 (1995). *
Bossard C, Souaze F, Jarry A, Bezieau S, Mosnier JF, Forgez P, Laboisse CL. Over-expression of neurotensin high-affinity receptor 1 (NTS1) in relation with its ligand neurotensin (NT) and nuclear beta-catenin in inflammatory bowel disease-related oncogenesis. Peptides 28: 2030-2035 (2007). *
Bosse Y, Maghni K, Hudson TJ. 1alpha,25-Dihydroxy-vitamin D3 stimulation of bronchial smooth muscle cells induces autocrine, contractility and remodelling processes. Physiol. Genomics 29: 161-168 (2007). *
Bosse Y, Rola-Pleszczynski M. Controversy surrounding the increased expression of TGFbeta1 in asthma. Respir. Res. 8: 66 (2007). *
Bossowski A, Czarnocka B, Bardadin K, Stasiak-Barmuta A, Urban M, Dadan J, Ratomski K, Bossowska A. Identification of apoptotic proteins in thyroid gland from patients with Graves' disease and Hashimoto's thyroiditis. Autoimmunity 41: 163-173 (2008).
Bossowski A, Czarnocka B, Stasiak-Barmuta A, Bardadin K, Urban M, Dadan J. Analysis of Fas, FasL and caspase-8 expression in thyroid gland in young patients with immune and non-immune thyroid diseases. Endokrynol. Pol. 58: 303-313 (2007).
Bossu P, Ciaramella A, Moro ML, Bellincampi L, Bernardini S, Federici G, Trequattrini A, Macciardi F, Spoletini I, Di Iulio F, Caltagirone C, Spalletta G. Interleukin-18 gene polymorphisms predict risk and outcome of Alzheimer's disease. J. Neurol. Neurosurg. Psychiatry 78: 807-811 (2007). *
Bostjancic E, Glavac D. Importance of microRNAs in skin morphogenesis and diseases. Acta Dermatovenerol. Alp. Panonica Adriat. 17: 95-102 (2008).
Bott C, Lembcke B, Stein J. Colorectal cancer and folate. Z. Gastroenterol. 41: 263-270 (2003).
Bottcher I, Bellinghausen I, K�nig B, Knop J, Saloga J. Different regulation of T helper 1- and T helper 2-promoting cytokine signalling factors in human dendritic cells after exposure to protein versus contact allergens. Immunology 123: 139-144 (2008). *
Bottcher S, Ritgen M, Bruggemann M, Raff T, Luschen S, Humpe A, Kneba M, Pott C. Flow cytometric assay for determination of FcgammaRIIIA-158 V/F polymorphism. J. Immunol. Methods 306: 128-136 (2005). *
Bottini N, Gloria-Bottini F, Lucarini N, Ronchetti PG, Fontana L. Inflammatory bowel disease: are there gender differences in the genetics of signal transduction? A preliminary study of cytosolic low molecular weight protein tyrosine phosphatase. Dis. Markers 16: 163-166 (2000).
Bouali H, Nietert P, Nowling TM, Pandey J, Dooley MA, Cooper G, Harley J, Kamen DL, Oates J, Gilkeson G. Association of the G-463A myeloperoxidase gene polymorphism with renal disease in African Americans with systemic lupus erythematosus. J. Rheumatol. 34: 2028-2034 (2007).
Bouchier-Hayes L, Conroy H, Egan H, Adrain C, Creagh EM, MacFarlane M, Martin SJ. CARDINAL, a novel caspase recruitment domain protein, is an inhibitor of multiple NF-kappa B activation pathways. J. Biol. Chem. 276: 44069-44077 (2001). *
Boudjelal M, Mason SJ, Katso RM, Fleming JM, Parham JH, Condreay JP, Merrihew RV, J Cairns W. The application of BacMam technology in nuclear receptor drug discovery. Biotechnol. Annu. Rev. 11: 101-125 (2005).
Bougarne N, Paumelle R, Caron S, Hennuyer N, Mansouri R, Gervois P, Staels B, Haegeman G, De Bosscher K. PPARalpha blocks glucocorticoid receptor alpha-mediated transactivation but cooperates with the activated glucocorticoid receptor alpha for transrepression on NF-kappaB. Proc. Natl. Acad. Sci. U.S.A. 106: 7397-7402 (2009). *
Boughan PK, Argent RH, Body-Malapel M, Park JH, Ewings KE, Bowie AG, Ong SJ, Cook SJ, Sorensen OE, Manzo BA, Inohara N, Klein NJ, Nunez G, Atherton JC, Bajaj-Elliott M. Nucleotide-binding oligomerization domain-1 and epidermal growth factor receptor: critical regulators of beta-defensins during Helicobacter pylori infection. J. Biol. Chem. 281: 11637-11648 (2006). *
Bouillon R, Verstuyf A, Mathieu C, Van Cromphaut S, Masuyama R, Dehaes P, Carmeliet G. Vitamin D resistance. Best Pract. Res. Clin. Endocrinol. Metab. 20: 627-645 (2006).
Boulanger A, McLemore P, Copeland NG, Gilbert DJ, Jenkins NA, Yu SS, Gentleman S, Redmond TM. Identification of beta-carotene 15, 15'-monooxygenase as a peroxisome proliferator-activated receptor target gene. FASEB J. 17: 1304-1306 (2003). *
Boulet LP. Influence of obesity on the prevalence and clinical features of asthma. Clin. Invest. Med. 31: E386 (2008).
Boulet S, Kleyman M, Kim JY, Kamya P, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection. AIDS 22: 1487-1491 (2008).
Boulet S, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals. AIDS 22: 595-599 (2008).
Boulias K, Katrakili N, Bamberg K, Underhill P, Greenfield A, Talianidis I. Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. EMBO J. 24: 2624-2633 (2005). *
Bouqbis L, Izaabel H, Akhayat O, Perez-Lezaun A, Calafell F, Bertranpetit J, Comas D. Association of the CTLA4 promoter region (-1661G allele) with type 1 diabetes in the South Moroccan population. Genes Immun. 4: 132-137 (2003). *
Bourdi M, Masubuchi Y, Reilly TP, Amouzadeh HR, Martin JL, George JW, Shah AG, Pohl LR. Protection against acetaminophen-induced liver injury and lethality by interleukin 10: role of inducible nitric oxide synthase. Hepatology 35: 289-298 (2002). *
Bourke B. Campylobacter infection: small bowel and colon. Curr. Opin. Gastroenterol. 18: 4-9 (2002).
Bourlier V, Zakaroff-Girard A, Miranville A, De Barros S, Maumus M, Sengenes C, Galitzky J, Lafontan M, Karpe F, Frayn KN, Bouloumie A. Remodeling phenotype of human subcutaneous adipose tissue macrophages. Circulation 117: 806-815 (2008). *
Bourquin C, van der Haar ME, Anz D, Sandholzer N, Neumaier I, Endres S, Skerra A, Schwab ME, Linington C. DNA vaccination efficiently induces antibodies to Nogo-A and does not exacerbate experimental autoimmune encephalomyelitis. Eur. J. Pharmacol. 588: 99-105 (2008).
Boursier L, Gordon JN, Thiagamoorthy S, Edgeworth JD, Spencer J. Human intestinal IgA response is generated in the organized gut-associated lymphoid tissue but not in the lamina propria. Gastroenterology 128: 1879-1889 (2005). *
Bouwens M, Afman LA, M�ller M. Activation of peroxisome proliferator-activated receptor alpha in human peripheral blood mononuclear cells reveals an individual gene expression profile response. BMC Genomics 9: 262 (2008). *
Bouwens M, van de Rest O, Dellschaft N, Bromhaar MG, de Groot LC, Geleijnse JM, Muller M, Afman LA. Fish-oil supplementation induces antiinflammatory gene expression profiles in human blood mononuclear cells. Am. J. Clin. Nutr. Jun 10 [Epub ahead of print] (2009).
Bovin LF, Brynskov J, Hegedus L, Jess T, Nielsen CH, Bendtzen K. Gene expression profiling in autoimmune diseases: chronic inflammation or disease specific patterns? Autoimmunity 40: 191-201 (2007).
Bovin LF, Rieneck K, Workman C, Nielsen H, Sorensen SF, Skjodt H, Florescu A, Brunak S, Bendtzen K. Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor. Immunol. Lett. 93: 217-226 (2004).
Bovo P, Mirakian R, Merigo F, Angelini G, Cavallini G, Rizzini P, Bottazzo GF, Scuro LA. HLA molecule expression on chronic pancreatitis specimens: is there a role for autoimmunity? A preliminary study. Pancreas 2: 350-356 (1987).
Bowcock AM. The genetics of psoriasis and autoimmunity. Annu. Rev. Genomics Hum. Genet. 6: 93-122 (2005). *
Bowcock AM, Krueger JG. Getting under the skin: the immunogenetics of psoriasis. Nat. Rev. Immunol. 5: 699-711 (2005). *
Bowcock AM, Shannon W, Du F, Duncan J, Cao K, Aftergut K, Catier J, Fernandez-Vina MA, Menter A. Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies. Hum. Mol. Genet. 10: 1793-1805 (2001). *
Bowden K, Ridgway ND. OSBP negatively regulates ABCA1 protein stability. J. Biol. Chem. 283: 18210-18217 (2008). *
Bowen H, Biggs TE, Phillips E, Baker ST, Perry VH, Mann DA, Barton CH. c-Myc represses and Miz-1 activates the murine natural resistance-associated protein 1 promoter. J. Biol. Chem. 277: 34997-35006 (2002). *
Bowlus CL. Chapter 11. Tumor immunology: hepatocellular carcinoma, cholangiocarcinoma, and metastatic neoplasms. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 137-149 (2007). *
Boxall S, Stanton T, Hirai K, Ward V, Yasui T, Tahara H, Tamori A, Nishiguchi S, Shiomi S, Ishiko O, Inaba M, Nishizawa Y, Dawes R, Bodmer W, Beverley PC, Tchilian EZ. Disease associations and altered immune function in CD45 138G variant carriers. Hum. Mol. Genet. 13: 2377-2384 (2004). *
Boyault S, Rickman DS, de Reynies A, Balabaud C, Rebouissou S, Jeannot E, Herault A, Saric J, Belghiti J, Franco D, Bioulac-Sage P, Laurent-Puig P, Zucman-Rossi J. Transcriptome classification of HCC is related to gene alterations and to new therapeutic targets. Hepatology 45: 42-52 (2007). *
Boyce BF, Schwarz EM, Xing L. Osteoclast precursors: cytokine-stimulated immunomodulators of inflammatory bone disease. Curr. Opin. Rheumatol. 18: 427-432 (2006).
Boyd JH, Divangahi M, Yahiaoui L, Gvozdic D, Qureshi S, Petrof BJ. Toll-like receptors differentially regulate CC and CXC chemokines in skeletal muscle via NF-kappaB and calcineurin. Infect. Immun. 74: 6829-6838 (2006). *
Boyella VD, Nicastri AD, Bergasa NV. Human hepatic met-enkephalin and delta opioid receptor-1 immunoreactivities in viral and autoimmune hepatitis. Ann. Hepatol. 7: 221-226 (2008). *
Boyer JL. New perspectives for the treatment of cholestasis: lessons from basic science applied clinically. J. Hepatol. 46: 365-371 (2007). *
Boyer JL. Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease? Gastroenterology 129: 735-740 (2005). *
Boyer JL, Denk G, Bohan A, Chen WS, Soroka C, Denson L. Adaptive regulation of bile salt transporters in cholestasis. Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 46-47. June 18-19 (2004). *
Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N. Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OSTalpha-OSTbeta, in cholestasis in humans and rodents. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1124-G1130 (2006). *
Boyle DL, Jones TL, Hammaker D, Svensson CI, Rosengren S, Albani S, Sorkin L, Firestein GS. Regulation of peripheral inflammation by spinal p38 MAP kinase in rats. PLoS Med. 3: e338 (2006). *
Boyle LH, Traherne JA, Plotnek G, Ward R, Trowsdale J. Splice variation in the cytoplasmic domains of myelin oligodendrocyte glycoprotein affects its cellular localisation and transport. J. Neurochem. 102: 1853-1862 (2007). *
Boyton RJ, Altmann DM. Natural killer cells, killer immunoglobulin-like receptors and human leucocyte antigen class I in disease. Clin. Exp. Immunol. 149: 1-8 (2007). *
Boyton RJ, Reynolds C, Wahid FN, Jones MG, Ozerovitch L, Ahmad T, Chaudhry A, Jewell DP, Kon OM, Smith J, Rose M, Newman-Taylor AJ, Cole P, Wilson R, Altmann DM. IFNgamma and CXCR-1 gene polymorphisms in idiopathic bronchiectasis. Tissue Antigens 68: 325-330 (2006). *
Bozzo F, Bocca C, Colombatto S, Miglietta A. Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways. Chem. Biol. Interact. 169: 110-121 (2007). *
Braat H, Stokkers P, Hommes T, Cohn D, Vogels E, Pronk I, Spek A, van Kampen A, van Deventer S, Peppelenbosch M, Hommes D. Consequence of functional Nod2 and Tlr4 mutations on gene transcription in Crohn's disease patients. J. Mol. Med. 83: 601-609 (2005). *
Brabender J, Metzger R, Salonga D, Danenberg KD, Danenberg PV, Holscher AH, Schneider PM. Comprehensive expression analysis of retinoic acid receptors and retinoid X receptors in non-small cell lung cancer: implications for tumor development and prognosis. Carcinogenesis 26: 525-530 (2005). *
Bracken S, Byrne G, Kelly J, Jackson J, Feighery C. Altered gene expression in highly purified enterocytes from patients with active coeliac disease. BMC Genomics 9: 377 (2008). *
Bradford EM, Sartor MA, Gawenis LR, Clarke LL, Shull GE. Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice. Am. J. Physiol. Gastrointest. Liver Physiol. 296: G886-G898 (2009). *
Bradl M, Lassmann DH. Anti-aquaporin-4 antibodies in neuromyelitis optica: how to prove their pathogenetic relevance? Int. MS J. 15: 75-78 (2008).
Bradley RL, Fisher FM, Maratos-Flier E. Dietary fatty acids differentially regulate production of TNF-alpha and IL-10 by murine 3T3-L1 adipocytes. Obesity (Silver Spring) 16: 938-944 (2008). *
Bradshaw S, Zheng WJ, Tsoi LC, Gilkeson G, Zhang XK. A role for Fli-1 in B cell proliferation: implications for SLE pathogenesis. Clin. Immunol. 129: 19-30 (2008). *
Braegger CP, MacDonald TT. Immune mechanisms in chronic inflammatory bowel disease. Ann. Allergy 72: 135-141 (1994).
Braff MH, Bardan A, Nizet V, Gallo RL. Cutaneous defense mechanisms by antimicrobial peptides. J. Invest. Dermatol. 125: 9-13 (2005). *
Brahmachari S, Pahan K. Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J. Immunol. 179: 275-283 (2007). *
Brahn E, Banquerigo ML, Lee JK, Park EJ, Fogler WE, Plum SM. An angiogenesis inhibitor, 2-methoxyestradiol, involutes rat collagen-induced arthritis and suppresses gene expression of synovial vascular endothelial growth factor and basic fibroblast growth factor. J. Rheumatol. 35: 2119-2128 (2008).
Braissant O, Foufelle F, Scotto C, Dauca M, Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 137: 354-366 (1996). *
Brambilla R, Persaud T, Hu X, Karmally S, Shestopalov VI, Dvoriantchikova G, Ivanov D, Nathanson L, Barnum SR, Bethea JR. Transgenic inhibition of astroglial NF-kappaB improves functional outcome in experimental autoimmune encephalomyelitis by suppressing chronic central nervous system inflammation. J. Immunol. 182: 2628-2640 (2009).
Bramlage CP, Kaps C, Ungethum U, Bramlage P, Koziolek M, Wessels J, Krenn V, Pruss A, Muller GA, Strutz F, Burmester GR, Haupl T. Modulatory effects of inflammation and therapy on GDF-5 expression in rheumatoid arthritis synovium. Scand. J. Rheumatol. 37: 401-409 (2008). *
Bramlett KS, Yao S, Burris TP. Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids. Mol. Genet. Metab. 71: 609-615 (2000). *
Brancaccio D, Bommer J, Coyne D. Vitamin D receptor activator selectivity in the treatment of secondary hyperparathyroidism: understanding the differences among therapies. Drugs 67: 1981-1998 (2007).
Brand A, Schonfeld E, Isharel I, Yavin E. Docosahexaenoic acid-dependent iron accumulation in oligodendroglia cells protects from hydrogen peroxide-induced damage. J. Neurochem. 105: 1325-1335 (2008). *
Brand DD, Kang AH, Rosloniec EF. Immunopathogenesis of collagen arthritis. Springer Semin. Immunopathol. 25: 3-18 (2003). *
Brand N, Petkovich M, Krust A, Chambon P, de The H, Marchio A, Tiollais P, Dejean A. Identification of a second human retinoic acid receptor. Nature 332: 850-853 (1988). *
Brand NJ, Petkovich M, Chambon P. Characterization of a functional promoter for the human retinoic acid receptor-alpha (hRAR-alpha). Nucleic Acids Res. 18: 6799-6806 (1990). *
Brand OJ, Barrett JC, Simmonds MJ, Newby PR, McCabe CJ, Bruce CK, Kysela B, Carr-Smith JD, Brix T, Hunt PJ, Wiersinga WM, Hegedus L, Connell J, Wass JA, Franklyn JA, Weetman AP, Heward JM, Gough SC. Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease. Hum. Mol. Genet. 18: 1704-1713 (2009).
Brand S, Beigel F, Olszak T, Zitzmann K, Eichhorst ST, Otte JM, Diepolder H, Marquardt A, Jagla W, Popp A, Leclair S, Herrmann K, Seiderer J, Ochsenkuhn T, Goke B, Auernhammer CJ, Dambacher J. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G827-G838 (2006). *
Brand S, Dambacher J, Beigel F, Zitzmann K, Heeg MH, Weiss TS, Prufer T, Olszak T, Steib CJ, Storr M, Goke B, Diepolder H, Bilzer M, Thasler WE, Auernhammer CJ. IL-22-mediated liver cell regeneration is abrogated by SOCS-1/3 overexpression in vitro. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G1019-G1028 (2007). *
Brand S, Hofbauer K, Dambacher J, Schnitzler F, Staudinger T, Pfennig S, Seiderer J, Tillack C, Konrad A, Goke B, Ochsenkuhn T, Lohse P. Increased expression of the chemokine fractalkine in Crohn's disease and association of the fractalkine receptor T280M polymorphism with a fibrostenosing disease phenotype. Am. J. Gastroenterol. 101: 99-106 (2006). *
Brandacher G, Margreiter R, Fuchs D. Implications of IFN-gamma-mediated tryptophan catabolism on solid organ transplantation. Curr. Drug Metab. 8: 273-282 (2007).
Brandacher G, Perathoner A, Ladurner R, Schneeberger S, Obrist P, Winkler C, Werner ER, Werner-Felmayer G, Weiss HG, Gobel G, Margreiter R, Konigsrainer A, Fuchs D, Amberger A. Prognostic value of indoleamine 2,3-dioxygenase expression in colorectal cancer: effect on tumor-infiltrating T cells. Clin. Cancer Res. 12: 1144-1151 (2006). *
Brandhagen D. Can liver transplantation improve our understanding of the pathophysiology of iron overload? Liver Transpl. 10: 1218-1220 (2004). *
Brandl K, Plitas G, Mihu CN, Ubeda C, Jia T, Fleisher M, Schnabl B, Dematteo RP, Pamer EG. Vancomycin-resistant enterococci exploit antibiotic-induced innate immune deficits. Nature 455: 804-807 (2008). *
Brandtzaeg P. Nature and function of gastrointestinal antigen-presenting cells. Allergy 56 Suppl. 67: 16-20 (2001).
Brandtzaeg P, Carlsen HS, Halstensen TS. The B-cell system in inflammatory bowel disease. Adv. Exp. Med. Biol. 579: 149-167 (2006).
Brant SR. Exposed: the genetic underpinnings of ulcerative colitis relative to Crohn's disease. Gastroenterology 136: 396-399 (2009). *
Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am. J. Hum. Genet.73: 1282-1292 (2003). *
Bratke K, Goettsching H, Kuepper M, Geyer S, Luttmann W, Virchow JC. Interleukin-4 suppresses the cytotoxic potential of in vitro generated, adaptive regulatory CD4(+) T cells by down-regulation of granzyme B. Immunology 127: 338-344 (2009). *
Bratland E, Bredholt G, Mellgren G, Knappskog PM, Mozes E, Husebye ES. The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: the major autoantigen in autoimmune Addison's disease. J. Autoimmun. 33: 58-67 (2009).
Bravo I, Amigo L, Cohen DE, Nervi F, Rigotti A, Francone O, Zanlungo S. Role of plasma and liver cholesterol- and lipoprotein-metabolism determinants in LpX formation in the mouse. Biochim. Biophys. Acta 1770: 979-988 (2007). *
Brazowski E, Rozen P, Misonzhnick-Bedny F, Gitstein G. Characteristics of familial juvenile polyps expressing cyclooxygenase-2. Am. J. Gastroenterol. 100: 130-138 (2005). *
Bream JH, Ping A, Zhang X, Winkler C, Young HA. A single nucleotide polymorphism in the proximal IFN-gamma promoter alters control of gene transcription. Genes Immun. 3: 165-169 (2002). *
Breant B, Gesina E, Blondeau B. Nutrition, glucocorticoids and pancreas development. Horm. Res. 65 Suppl. 3: 98-104 (2006).
Breban M, Hacquard-Bouder C, Falgarone G. Animal models of HLA-B27-associated diseases. Curr. Mol. Med. 4: 31-40 (2004).
Brechot C. Pathogenesis of hepatitis B virus-related hepatocellular carcinoma: old and new paradigms. Gastroenterology 127 (5 Suppl. 2): S56-S61 (2004). *
Bregenholt S, Brimnes J, Nissen MH, Claesson MH. In vitro activated CD4+ T cells from interferon-gamma (IFN-gamma)-deficient mice induce intestinal inflammation in immunodeficient hosts. Clin. Exp. Immunol. 118: 228-234 (1999). *
Breinig M, Caldas-Lopes E, Goeppert B, Malz M, Rieker R, Bergmann F, Schirmacher P, Mayer M, Chiosis G, Kern MA. Targeting heat shock protein 90 with non-quinone inhibitors: a novel chemotherapeutic approach in human hepatocellular carcinoma. Hepatology Feb 18 [Epub ahead of print] (2009).
Breitkopf K, Sawitza I, Westhoff JH, Wickert L, Dooley S, Gressner AM. Thrombospondin 1 acts as a strong promoter of transforming growth factor beta effects via two distinct mechanisms in hepatic stellate cells. Gut 54: 673-681 (2005). *
Brem RB, Kruglyak L. The landscape of genetic complexity across 5,700 gene expression traits in yeast. Proc. Natl. Acad. Sci. U.S.A. 102: 1572-1577 (2005). *
Brendel C, Schoonjans K, Botrugno OA, Treuter E, Auwerx J. The small heterodimer partner interacts with the liver X receptor alpha and represses its transcriptional activity. Mol. Endocrinol. 16: 2065-2076 (2002). *
Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y. Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc. Natl. Acad. Sci. U.S.A. 101: 16016-16021 (2004). *
Brentano F, Kyburz D, Gay S. Toll-like receptors and rheumatoid arthritis. Methods Mol. Biol. 517: 1-15 (2009). *
Brentnall TA. Ursodiol: good drug makes good. Gastroenterology 124: 1139-1140 (2003). *
Breslin NP, Todd A, Kilgallen C, O'Morain C. Monozygotic twins with Crohn's disease and ulcerative colitis: a unique case report. Gut 41: 557-560 (1997). *
Bresolin T, de Freitas Rebelo M, Celso Dias Bainy A. Expression of PXR, CYP3A and MDR1 genes in liver of zebrafish. Comp. Biochem. Physiol. C. Toxicol. Pharmacol. 140: 403-407 (2005). *
Breuhahn K, Baeuerle PA, Peters M, Prang N, Tox U, Kohne-Volland R, Dries V, Schirmacher P, Leo E. Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma. Hepatol. Res. 34: 50-56 (2006).
Breulmann B, Bantis C, Siekierka M, Blume C, Aker S, Kuhr N, Grabensee B, Ivens K. Influence of cytokine genes polymorphisms on long-term outcome in renal transplantation. Clin. Transplant. 21: 615-621 (2007). *
Breunis WB, van Mirre E, Geissler J, Laddach N, Wolbink G, van der Schoot E, de Haas M, de Boer M, Roos D, Kuijpers TW. Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B. Hum. Mutat. 30: E640-E650 (2009). *
Brewer M, Kirkpatrick ND, Wharton JT, Wang J, Hatch K, Auersperg N, Utzinger U, Gershenson D, Bast R, Zou C. 4-HPR modulates gene expression in ovarian cells. Int. J. Cancer 119: 1005-1013 (2006). *
Briani C, Samaroo D, Alaedini A. Celiac disease: from gluten to autoimmunity. Autoimmun. Rev. 7: 644-650 (2008).
Bridges KR. Iron overload and chelation therapy. ENCYCLOPEDIA OF LIFE SCIENCES Nature Publishing Group www.els.net (2001). *
Bridle KR, Frazer DM, Wilkins SJ, Dixon JL, Purdie DM, Crawford DH, Subramaniam VN, Powell LW, Anderson GJ, Ramm GA. Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis. Lancet 361: 669-673 (2003). *
Brigelius-Flohe R. Vitamin E and drug metabolism. Biochem. Biophys. Res. Commun. 305: 737-740 (2003). *
Brigelius-Flohe R. Induction of drug metabolizing enzymes by vitamin E. J. Plant Physiol. 162: 797-802 (2005).
Briggs L, Laird K, Boss JM, Garvie CW. Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP. Proteins Jan 23 [Epub ahead of print] (2009).
Brilot F, Geenen V. Role of viral infections in the pathogenesis of type 1 diabetes. Rev. Med. Liege 60: 297-302 (2005).
Brinckerhoff CE, Sporn MB. Retinoids and rexinoids for the 21st century: a brave new world for arthritis. J. Rheumatol. 30: 211-213 (2003).
Bringer MA, Rolhion N, Glasser AL, Darfeuille-Michaud A. The oxidoreductase DsbA plays a key role in the ability of the Crohn's disease-associated adherent-invasive Escherichia coli strain LF82 to resist macrophage killing. J. Bacteriol. 189: 4860-4871 (2007). *
Brisebois M, Zehntner SP, Estrada J, Owens T, Fournier S. A pathogenic role for CD8+ T cells in a spontaneous model of demyelinating disease. J. Immunol. 177: 2403-2411 (2006). *
Briskin M, Winsor-Hines D, Shyjan A, Cochran N, Bloom S, Wilson J, McEvoy LM, Butcher EC, Kassam N, Mackay CR, Newman W, Ringler DJ. Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. Am. J. Pathol. 151: 97-110 (1997). *
Brisslert M, Bokarewa M, Larsson P, Wing K, Collins LV, Tarkowski A. Phenotypic and functional characterization of human CD25 B cells. Immunology 117: 548-557 (2006). *
Bristol JA, Morrison TE, Kenney SC. CCAAT/enhancer binding proteins alpha and beta regulate the tumor necrosis factor receptor 1 gene promoter. Mol. Immunol. Jun 10 [Epub ahead of print] (2009).
Bristow CA, Shore P. Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ. Nucleic Acids Res. 31: 2735-2744 (2003). *
Brites D, Fernandes A, Falcao AS, Gordo AC, Silva RF, Brito MA. Biological risks for neurological abnormalities associated with hyperbilirubinemia. J. Perinatol. 29 Suppl. 1: S8-S13 (2009).
Britten AC, Mijovic CH, Barnett AH, Kelly MA. Differential expression of HLA-DQ alleles in peripheral blood mononuclear cells: alleles associated with susceptibility to and protection from autoimmune type 1 diabetes. Int. J. Immunogenet. 36: 47-57 (2009). *
Brockmann JG, August C, Wolters HH, Homme R, Palmes D, Baba H, Spiegel HU, Dietl KH. Sequence of reperfusion influences ischemia/reperfusion injury and primary graft function following porcine liver transplantation. Liver Transpl. 11: 1214-1222 (2005). *
Broderick G, Craddock RC, Whistler T, Taylor R, Klimas N, Unger ER. Identifying illness parameters in fatiguing syndromes using classical projection methods. Pharmacogenomics 7: 407-419 (2006).
Brodin P, Karre K, Hoglund P. NK cell education: not an on-off switch but a tunable rheostat. Trends Immunol. 30: 143-149 (2009). *
Brody F, Hill S, Celenski S, Kar R, Kluk B, Pinzone J, Fu S. Expression of ectonucleotide pyrophosphate phosphodiesterase and peroxisome proliferator activated receptor gamma in morbidly obese patients. Surg. Endosc. 21: 941-944 (2007). *
Broering R, Wu J, Meng Z, Hilgard P, Lu M, Trippler M, Szczeponek A, Gerken G, Schlaak JF. Toll-like receptor-stimulated non-parenchymal liver cells can regulate hepatitis C virus replication. J. Hepatol. 48: 914-922 (2008).
Broersen K, Brink DV, Fraser G, Goedert M, Davletov B. alpha-Synuclein adopts an alpha-helical conformation in the presence of polyunsaturated fatty acids to hinder micelle formation. Biochemistry 45: 15610-15616 (2006). *
Brogan PA, Shah V, Klein N, Dillon MJ. Vbeta-restricted T cell adherence to endothelial cells: a mechanism for superantigen-dependent vascular injury. Arthritis Rheum. 50: 589-597 (2004). *
Bromley SK, Mempel TR, Luster AD. Orchestrating the orchestrators: chemokines in control of T cell traffic. Nat. Immunol. 9: 970-980 (2008). *
Bronsveld I, Mekus F, Bijman J, Ballmann M, de Jonge HR, Laabs U, Halley DJ, Ellemunter H, Mastella G, Thomas S, Veeze HJ, Tummler B. Chloride conductance and genetic background modulate the cystic fibrosis phenotype of Delta F508 homozygous twins and siblings. J. Clin. Invest. 108: 1705-1715 (2001). *
Brookes MJ, Hughes S, Turner FE, Reynolds G, Sharma N, Ismail T, Berx G, McKie AT, Hotchin N, Anderson GJ, Iqbal T, Tselepis C. A modulation of iron transport proteins in human colorectal carcinogenesis. Gut 55: 1449-1460 (2006). *
Brooks AG, Boyington JC, Sun PD. Natural killer cell recognition of HLA class I molecules. Rev. Immunogenet. 2: 433-448 (2000).
Brooks WH. Autoimmune disorders result from loss of epigenetic control following chromosome damage. Med. Hypotheses 64: 590-598 (2005).
Broom OJ, Massoumi R, Sjolander A. alpha2beta1 integrin signalling enhances cyclooxygenase-2 expression in intestinal epithelial cells. J. Cell. Physiol. 209: 950-958 (2006). *
Broome U, Grunewald J, Scheynius A, Olerup O, Hultcrantz R. Preferential V beta3 usage by hepatic T lymphocytes in patients with primary sclerosing cholangitis. J. Hepatol. 26: 527-534 (1997). *
Broome U, Scheynius A, Hultcrantz R. Induced expression of heat-shock protein on biliary epithelium in patients with primary sclerosing cholangitis and primary biliary cirrhosis. Hepatology 18: 298-303 (1993).
Brophy CM, Luebke-Wheeler JL, Amiot BP, Khan H, Remmel RP, Rinaldo P, Nyberg SL. Rat hepatocyte spheroids formed by rocked technique maintain differentiated hepatocyte gene expression and function. Hepatology 49: 578-586 (2009).
Brouillard F, Bensalem N, Hinzpeter A, Tondelier D, Trudel S, Gruber AD, Ollero M, Edelman A. Blue native-SDS PAGE analysis reveals reduced expression of the mClCA3 protein in cystic fibrosis knock-out mice. Mol. Cell. Proteomics 4: 1762-1775 (2005). *
Brousseau ME. ATP-binding cassette transporter A1, fatty acids, and cholesterol absorption. Curr. Opin. Lipidol. 14: 35-40 (2003).
Brousseau ME, Hoeg JM. Transgenic rabbits as models for atherosclerosis research. J. Lipid Res. 40: 365-375 (1999). *
Brouwer E, Tervaert JW, Horst G, Huitema MG, van der Giessen M, Limburg PC, Kallenberg CG. Predominance of IgG1 and IgG4 subclasses of anti-neutrophil cytoplasmic autoantibodies (ANCA) in patients with Wegener's granulomatosis and clinically related disorders. Clin. Exp. Immunol. 83: 379-386 (1991). *
Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, Manning C, Voland C, Goldring SR, Goldring MB, Libermann TA, Gravalllese EM, Oettgen P. ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. J. Biol. Chem. 279: 12794-12803 (2004). *
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. J. Biol. Chem. 279: 34674-34681 (2004). *
Brown KL, Bylund J, Macdonald KL, Song-Zhao GX, Elliott MR, Falsafi R, Hancock RE, Speert DP. ROS-deficient monocytes have aberrant gene expression that correlates with inflammatory disorders of chronic granulomatous disease. Clin. Immunol. 129: 90-102 (2008). *
Brown KS, Nackos E, Morthala S, Jensen LE, Whitehead AS, VON Feldt JM. Independent role of conventional cardiovascular risk factors as predictors of C-reactive protein concentrations in rheumatoid arthritis. J. Rheumatol. 34: 740-746 (2007).
Brown L, Ongusaha PP, Kim HG, Nuti S, Mandinova A, Lee JW, Khosravi-Far R, Aaronson SA, Lee SW. CDIP, a novel pro-apoptotic gene, regulates TNFalpha-mediated apoptosis in a p53-dependent manner. EMBO J. 26: 3410-3422 (2007). *
Brown NK, McCormick DJ, David CS, Kong YC. H2E-derived Ealpha52-68 peptide presented by H2Ab interferes with clonal deletion of autoreactive T cells in autoimmune thyroiditis. J. Immunol. 180: 7039-7046 (2008). *
Brown SJ, Abreu MT. Antibodies to tumor necrosis factor-alpha in the treatment of Crohn's disease. Curr. Opin. Drug Discov. Devel. 8: 160-168 (2005).
Brown TR, Stonehouse TJ, Branch JS, Brickell PM, Katz DR. Stable transfection of U937 cells with sense or antisense RXR-alpha cDNA suggests a role for RXR-alpha in the control of monoblastic differentiation induced by retinoic acid and vitamin D. Exp. Cell Res. 236: 94-102 (1997). *
Brozek W, Bises G, Fabjani G, Cross HS, Peterlik M. Clone-specific expression, transcriptional regulation, and action of interleukin-6 in human colon carcinoma cells. BMC Cancer 8: 13 (2008). *
Brtko J, Rock E, Nezbedova P, Krizanova O, Dvorcakova M, Minet-Quinard R, Farges MC, Ribalta J, Winklhofer-Roob BM, Vasson MP, Macejova D. Age-related change in the retinoid X receptor beta gene expression in peripheral blood mononuclear cells of healthy volunteers: effect of 13-cis retinoic acid supplementation. Mech. Ageing Dev. 128: 594-600 (2007).
Brucet M, Marques L, Sebastian C, Lloberas J, Celada A. Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1. Genes Immun. 5: 26-35 (2004). *
Bruck R, Ashkenazi M, Weiss S, Goldiner I, Shapiro H, Aeed H, Genina O, Helpern Z, Pines M. Prevention of liver cirrhosis in rats by curcumin. Liver Int. 27: 373-383 (2007). *
Brudzewsky D, Pedersen AE, Claesson MH, Gad M, Kristensen NN, Lage K, Jensen T, Tommerup N, Larsen LA, Knudsen S, Tumer Z. Genome-wide gene expression profiling of SCID mice with T-cell-mediated colitis. Scand. J. Immunol. 69: 437-446 (2009). *
Bruemmer D, Law RE. Liver X receptors: potential novel targets in cardiovascular diseases. Curr. Drug Targets Cardiovasc. Haematol. Disord. 5: 533-540 (2005).
Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Reed JC. PAN1/NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kB and caspase-1 activation in macrophages. J. Biol. Chem. 279: 51897-51907 (2004). *
Brummelkamp T, Nijman S, Dirac A, Bernards R. High throughput loss-of-function phenotypic screens in mammalian cells. Falk Symposium 138. XII FALK LIVER WEEK 2003 (Part III) In Honour of Hans Popper�s 100th Birthday. State-of-the-art of hepatology: Molecular and Cell Biology. Freiburg (Germany). p. 52. October 20 - 21 (2003). *
Brun T, Gauthier BR. A focus on the role of Pax4 in mature pancreatic islet beta-cell expansion and survival in health and disease. J. Mol. Endocrinol. 40: 37-45 (2008). *
Brundage SI, Kirilcuk NN, Lam JC, Spain DA, Zautke NA. Insulin increases the release of proinflammatory mediators. J. Trauma 65: 367-372 (2008).
Brune CW, Kim SJ, Salt J, Leventhal BL, Lord C, Cook EH Jr. 5-HTTLPR genotype-specific phenotype in children and adolescents with autism. Am. J. Psychiatry 163: 2148-2156 (2006).
Brunelli L, Cieslik KA, Alcorn JL, Vatta M, Baldini A. Peroxisome proliferator-activated receptor-delta upregulates 14-3-3varepsilon in human endothelial cells via CCAAT/enhancer binding protein-beta. Circ. Res. 100: e59-e71 (2007). *
Brunham LR, Kruit JK, Pape TD, Parks JS, Kuipers F, Hayden MR. Tissue-specific induction of intestinal ABCA1 expression with a liver X receptor agonist raises plasma HDL cholesterol levels. Circ. Res. 99: 672-674 (2006). *
Bruno ME, Kaetzel CS. Long-term exposure of the HT-29 human intestinal epithelial cell line to TNF causes sustained up-regulation of the polymeric Ig receptor and proinflammatory genes through transcriptional and posttranscriptional mechanisms. J. Immunol. 174: 7278-7284 (2005). *
Bruno ME, West RB, Schneeman TA, Bresnick EH, Kaetzel CS. Upstream stimulatory factor but not c-Myc enhances transcription of the human polymeric immunoglobulin receptor gene. Mol. Immunol. 40: 695-708 (2004). *
Bruno R, Ferretti E, Tosi E, Arturi F, Giannasio P, Mattei T, Scipioni A, Presta I, Morisi R, Gulino A, Filetti S, Russo D. Modulation of thyroid-specific gene expression in normal and nodular human thyroid tissues from adults: an in vivo effect of thyrotropin. J. Clin. Endocrinol. Metab. 90: 5692-5697 (2005). *
Brunt EM, Swanson PE. Immunoreactivity for c-erbB-2 oncopeptide in benign and malignant diseases of the liver. Am. J. Clin. Pathol. 97: S53-S61 (1992).
Brush MH, Shenolikar S. Control of cellular GADD34 levels by the 26S proteasome. Mol. Cell. Biol. 28: 6989-7000 (2008). *
Brustle A, Heink S, Huber M, Rosenplanter C, Stadelmann C, Yu P, Arpaia E, Mak TW, Kamradt T, Lohoff M. The development of inflammatory T(H)-17 cells requires interferon-regulatory factor 4. Nat. Immunol. 8: 958-966 (2007). *
Bruwer M, Schmid KW, Senninger N, Schurmann G. Immunohistochemical expression of P53 and oncogenes in ulcerative colitis-associated colorectal carcinoma. World J. Surg. 26: 390-396 (2002). *
Bruzzese V, Pepe J. Efficacy of cyclosporine in the treatment of a case of infliximab-induced erythrodermic psoriasis. Int. J. Immunopathol. Pharmacol. 22: 235-238 (2009).
Bryceson YT, March ME, Ljunggren HG, Long EO. Activation, coactivation, and costimulation of resting human natural killer cells. Immunol. Rev. 214: 73-91 (2006). *
Bryl E, Vallejo AN, Matteson EL, Witkowski JM, Weyand CM, Goronzy JJ. Modulation of CD28 expression with anti-tumor necrosis factor alpha therapy in rheumatoid arthritis. Arthritis Rheum. 52: 2996-3003 (2005). *
Bryzgalov LO, Ershov NI, Oshchepkov DY, Kaledin VI, Merkulova TI. Detection of target genes of FOXA transcription factors involved in proliferation control. Biochemistry (Mosc.) 73: 70-75 (2008).
Bsibsi M, Bajramovic JJ, Van Duijvenvoorden E, Persoon C, Ravid R, Van Noort JM, Vogt MH. Identification of soluble CD14 as an endogenous agonist for Toll-like receptor 2 on human astrocytes by genome-scale functional screening of glial cell derived proteins. Glia 55: 473-482 (2007).
Bsibsi M, Persoon-Deen C, Verwer RW, Meeuwsen S, Ravid R, Van Noort JM. Toll-like receptor 3 on adult human astrocytes triggers production of neuroprotective mediators. Glia 53: 688-695 (2006).
Bu D, Tomlinson G, Lewis CM, Zhang C, Kildebeck E, Euhus DM. An intronic polymorphism associated with increased XRCC1 expression, reduced apoptosis and familial breast cancer. Breast Cancer Res. Treat. 99: 257-265 (2006). *
Bu P, Wan YJ. Fenretinide-induced apoptosis of Huh-7 hepatocellular carcinoma is retinoic acid receptor beta dependent. BMC Cancer 7: 236 (2007). *
Buch MH, Boyle DL, Rosengren S, Saleem B, Reece RJ, Rhodes LA, Radjenovic A, English A, Tang H, Vratsanos G, O'Connor P, Firestein GS, Emery P. Mode of action of abatacept in rheumatoid arthritis patients having failed TNF blockade: a histological, gene expression and dynamic MRI pilot study. Ann. Rheum. Dis. 68: 1220-1227 (2009).
Buch MH, Reece RJ, Quinn MA, English A, Cunnane G, Henshaw K, Bingham SJ, Bejarano V, Isaacs J, Emery P. The value of synovial cytokine expression in predicting the clinical response to TNF antagonist therapy (infliximab). Rheumatology (Oxford) 47: 1469-1475 (2008). *
Buchert M, Darido C, Lagerqvist E, Sedello A, Cazevieille C, Buchholz F, Pannequin J, Joubert D, Hollande F. The symplekin/ZONAB complex inhibits intestinal cell differentiation via the repression of AML1/Runx1. Gastroenterology Mar 26 [Epub ahead of print] (2009).
Buchwald M, Sood R, Auerbach W. Regulation of expression of CFTR in human intestinal epithelial cells. Adv. Exp. Med. Biol. 290: 241-250 (1991).
Buchwald PC, Westin G, Akerstrom G. Vitamin D in normal and pathological parathyroid glands: new prospects for treating hyperparathyroidism (review). Int. J. Mol. Med. 15: 701-706 (2005).
Bucin D, Truedsson L, Hammarstrom L, Smith CI, Sjoholm AG. C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes. Exp. Clin. Immunogenet. 8: 233-241 (1991).
Buck D, Kroner A, Rieckmann P, Maurer M, Wiendl H. Analysis of the C/T(-1)) single nucleotide polymorphism in the CD40 gene in multiple sclerosis. Tissue Antigens 68: 335-338 (2006). *
Buck I, Morceau F, Cristofanon S, Reuter S, Dicato M, Diederich M. The inhibitory effect of the proinflammatory cytokine TNFalpha on erythroid differentiation involves erythroid transcription factor modulation. Int. J. Oncol. 34: 853-860 (2009).
Buckley DB, Klaassen CD. Induction of mouse UDP-glucuronosyltransferase mRNA expression in liver and intestine by activators of AhR, CAR, PXR, PPARalpha, and Nrf2. Drug Metab. Dispos. 37: 847-856 (2009). *
Buckley SM, Waddington S, Jezzard S, Bergau A, Themis M, Macvinish L, Cuthbert A, Colledge W, Coutelle C. Intra-amniotic delivery of CFTR-expressing adenovirus does not reverse cystic fibrosis phenotype in inbred CFTR-knockout mice. Mol. Ther. 16: 819-824 (2008).
Bucova M, Bernadic M, Buckingham T. C-reactive protein, cytokines and inflammation in cardiovascular diseases. Bratisl. Lek. Listy. 109: 333-340 (2008).
Budagian V, Bulanova E, Orinska Z, Ludwig A, Rose-John S, Saftig P, Borden EC, Bulfone-Paus S. Natural soluble interleukin-15Ralpha is generated by cleavage that involves the tumor necrosis factor-alpha-converting enzyme (TACE/ADAM17). J. Biol. Chem. 279: 40368-40375 (2004). *
Buenafe AC, Bourdette DN. Lipopolysaccharide pretreatment modulates the disease course in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 182: 32-40 (2007).
Buendia MA. Liver cancer. Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 20-21 (2006). *
Bueno AA, Oyama LM, de Oliveira C, Pisani LP, Ribeiro EB, Silveira VL, Oller do Nascimento CM. Effects of different fatty acids and dietary lipids on adiponectin gene expression in 3T3-L1 cells and C57BL/6J mice adipose tissue. Pflugers Arch. 455: 701-709 (2008). *
Bueno MR, Daneri A, Armendariz-Borunda J. Cholestasis-induced fibrosis is reduced by interferon alpha-2a and is associated with elevated liver metalloprotease activity. J. Hepatol. 33: 915-925 (2000). *
Buetler TM. Identification of glutathione S-transferase isozymes and gamma-glutamylcysteine synthetase as negative acute-phase proteins in rat liver. Hepatology 28: 1551-1560 (1998). *
Buettner R, Parhofer KG, Woenckhaus M, Wrede CE, Kunz-Schughart LA, Scholmerich J, Bollheimer LC. Defining high-fat-diet rat models: metabolic and molecular effects of different fat types. J. Mol. Endocrinol. 36: 485-501 (2006). *
Bugge A, Grontved L, Aagaard MM, Borup R, Mandrup S. The PPARgamma2 A/B-domain plays a gene specific role in transactivation and co-factor recruitment. Mol. Endocrinol. 23: 794-808 (2009). *
Bugianesi E, McCullough AJ, Marchesini G. Insulin resistance: a metabolic pathway to chronic liver disease. Hepatology 42: 987-1000 (2005). *
Buhler MM, Craig M, Donaghue KC, Badhwar P, Willis J, Manolios N, Tait BD, Silink M, Bennetts BH, Stewart GJ. CCR5 genotyping in an Australian and New Zealand type 1 diabetes cohort. Autoimmunity 35: 457-461 (2002).
Buis CI, Geuken E, Visser DS, Kuipers F, Haagsma EB, Verkade HJ, Porte RJ. Altered bile composition after liver transplantation is associated with the development of nonanastomotic biliary strictures. J. Hepatol. 50: 69-79 (2009). *
Buis CI, van der Steege G, Visser DS, Nolte IM, Hepkema BG, Nijsten M, Slooff MJ, Porte RJ. Heme oxygenase-1 genotype of the donor is associated with graft survival after liver transplantation. Am. J. Transplant. 8: 377-385 (2008).
Buisine MP, Desreumaux P, Debailleul V, Gambiez L, Geboes K, Ectors N, Delescaut MP, Degand P, Aubert JP, Colombel JF, Porchet N. Abnormalities in mucin gene expression in Crohn's disease. Inflamm. Bowel Dis. 5: 24-32 (1999). *
Buisine MP, Desreumaux P, Leteurtre E, Copin MC, Colombel JF, Porchet N, Aubert JP. Mucin gene expression in intestinal epithelial cells in Crohn's disease. Gut 49: 544-551 (2001). *
Buisine MP, Devisme L, Degand P, Dieu MC, Gosselin B, Copin MC, Aubert JP, Porchet N. Developmental mucin gene expression in the gastroduodenal tract and accessory digestive glands. II. Duodenum and liver, gallbladder, and pancreas. J. Histochem. Cytochem. 48: 1667-1676 (2000). *
Bulian P, Gaidano G, Poeta GD, Gattei V. CD49d expression in chronic lymphocytic leukemia: a prognostic parameter and a therapeutic target. Future Oncol. 4: 355-358 (2008).
Bullard DC, Hu X, Adams JE, Schoeb TR, Barnum SR. p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis. Am. J. Pathol. 170: 2001-2008 (2007). *
Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis. J. Immunol. 178: 851-857 (2007). *
Bungard CI, McGivan JD. Identification of the promoter elements involved in the stimulation of ASCT2 expression by glutamine availability in HepG2 cells and the probable involvement of FXR/RXR dimers. Arch. Biochem. Biophys. 443: 53-59 (2005). *
Bunger M, Hooiveld GJ, Kersten S, Muller M. Exploration of PPAR functions by microarray technology - a paradigm for nutrigenomics. Biochim. Biophys. Acta 1771: 1046-1064 (2007). *
Bunger M, van den Bosch HM, van der Meijde J, Kersten S, Hooiveld GJ, Muller M. Genome-wide analysis of PPARalpha activation in murine small intestine. Physiol. Genomics 30: 192-204 (2007). *
Buning C, Schmidt HH, Molnar T, DE Jong DJ, Fiedler T, Buhner S, Sturm A, Baumgart DC, Nagy F, Lonovics J, Drenth JP, Landt O, Nickel R, Buttner J, Lochs H, Witt H. Heterozygosity for IL23R p.Arg381Gln confers a protective effect not only against Crohn's disease but also ulcerative colitis. Aliment. Pharmacol. Ther. 26: 1025-1033 (2007). *
Bunk R, Dittrich AM, Schulze I, Horn J, Schmolke K, Volk HD, Wahn V, Hoflich C. Rapid whole blood flow cytometric test to detect ICOS deficiency in patients with common variable immunodeficiency. Int. Arch. Allergy Immunol. 140: 342-344 (2006).
Bur IM, Cohen-Solal AM, Carmignac D, Abecassis PY, Chauvet N, Martin AO, van der Horst GT, Robinson IC, Maurel P, Mollard P, Bonnefont X. The circadian clock components CRY1 and CRY2 are necessary to sustain sex dimorphism in mouse liver metabolism. J. Biol. Chem. 284: 9066-9073 (2009). *
Burchill MA, Yang J, Vogtenhuber C, Blazar BR, Farrar MA. IL-2 receptor beta-dependent STAT5 activation is required for the development of Foxp3+ regulatory T cells. J. Immunol. 178: 280-290 (2007). *
Burczynski ME, Peterson RL, Twine NC, Zuberek KA, Brodeur BJ, Casciotti L, Maganti V, Reddy PS, Strahs A, Immermann F, Spinelli W, Schwertschlag U, Slager AM, Cotreau MM, Dorner AJ. Molecular classification of Crohn's disease and ulcerative colitis patients using transcriptional profiles in peripheral blood mononuclear cells. J. Mol. Diagn. 8: 51-61 (2006). *
Burek CL, Rose NR. Autoimmune thyroiditis and ROS. Autoimmun. Rev. 7: 530-537 (2008).
Buren M, Yamashita M, Suzuki Y, Tomino Y, Emancipator SN. Altered expression of lymphocyte homing chemokines in the pathogenesis of IgA nephropathy. Contrib. Nephrol. 157: 50-55 (2007).
Burgener IA, Konig A, Allenspach K, Sauter SN, Boisclair J, Doherr MG, Jungi TW. Upregulation of Toll-like receptors in chronic enteropathies in dogs. J. Vet. Intern. Med. 22: 553-560 (2008).
Burger D, Molnarfi N, Weber MS, Brandt KJ, Benkhoucha M, Gruaz L, Chofflon M, Zamvil SS, Lalive PH. Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1beta in human monocytes and multiple sclerosis. Proc. Natl. Acad. Sci. U.S.A. 106: 4355-4359 (2009). *
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lutjohann D, Demattos RB, Wellington CL. ABCG1 influences brain cholesterol synthesis but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo. J. Lipid Res. 49: 1254-1267 (2008). *
Burgler S, Ouaked N, Bassin C, Basinski TM, Mantel PY, Siegmund K, Meyer N, Akdis CA, Schmidt-Weber CB. Differentiation and functional analysis of human T(H)17 cells. J. Allergy Clin. Immunol. 123: 588-595, 595.e1-e7 (2009).
Burgos JS, Serrano-Saiz E, Sastre I, Valdivieso F. ICP47 mediates viral neuroinvasiveness by induction of TAP protein following intravenous inoculation of herpes simplex virus type 1 in mice. J. Neurovirol. 12: 420-427 (2006).
Burich A, Hershberg R, Waggie K, Zeng W, Brabb T, Westrich G, Viney JL, Maggio-Price L. Helicobacter-induced inflammatory bowel disease in IL-10- and T cell-deficient mice. Am. J. Physiol. Gastrointest. Liver Physiol. 281: G764-G778 (2001). *
Burk O, Arnold KA, Geick A, Tegude H, Eichelbaum M. A role for constitutive androstane receptor in the regulation of human intestinal MDR1 expression. Biol. Chem. 386: 503-513 (2005).
Burk O, Arnold KA, Nussler AK, Schaeffeler E, Efimova E, Avery BA, Avery MA, Fromm MF, Eichelbaum M. Anti-malarial artemisinin drugs induce CYP and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor. Mol. Pharmacol. 67: 1954-1965 (2005). *
Burkart KM, Barton SJ, Holloway JW, Yang IA, Cakebread JA, Cruikshank W, Little F, Jin X, Farrer LA, Clough JB, Keith TP, Holgate S, Center DM, O'connor GT. Association of asthma with a functional promoter polymorphism in the IL16 gene. J. Allergy Clin. Immunol. 117: 86-91 (2006). *
Burke JP, Ferrante M, Dejaegher K, Watson RW, Docherty NG, De Hertogh G, Vermeire S, Rutgeerts P, D'Hoore A, Penninckx F, Geboes K, Van Assche G, O'Connell PR. Transcriptomic analysis of intestinal fibrosis-associated gene expression in response to medical therapy in Crohn's disease. Inflamm. Bowel Dis. 14: 1197-1204 (2008). *
Burke ZD, Reed KR, Phesse TJ, Sansom OJ, Clarke AR, Tosh D. Liver zonation occurs through a beta-catenin dependent, c-Myc independent mechanism. Gastroenterology 136: 2316-2324.e3 (2009).
Burkly LC, Michaelson JS, Hahm K, Jakubowski A, Zheng TS. TWEAKing tissue remodeling by a multifunctional cytokine: role of TWEAK/Fn14 pathway in health and disease. Cytokine 40: 1-16 (2007).
Burl S, Hill PC, Jeffries DJ, Holland MJ, Fox A, Lugos MD, Adegbola RA, Rook GA, Zumla A, McAdam KP, Brookes RH. FOXP3 gene expression in a tuberculosis case contact study. Clin. Exp. Immunol. 149: 117-122 (2007). *
Burnat G, Rau T, Elshimi E, Hahn EG, Konturek PC. Bile acids induce overexpression of homeobox gene CDX-2 and vascular endothelial growth factor (VEGF) in human Barrett's esophageal mucosa and adenocarcinoma cell line. Scand. J. Gastroenterol. 42: 1460-1465 (2007). *
Burns CE, Traver D, Mayhall E, Shepard JL, Zon LI. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 19: 2331-2342 (2005). *
Burns KA, Vanden Heuvel JP. Modulation of PPAR activity via phosphorylation. Biochim. Biophys. Acta 1771: 952-960 (2007). *
Buroker NE, Barboza J, Huang JY. The IkappaBalpha gene is a peroxisome proliferator-activated receptor cardiac target gene. FEBS J. Apr 29 [Epub ahead of print] (2009). *
Buroker NE, Young ME, Wei C, Serikawa K, Ge M, Ning XH, Portman MA. The dominant negative thyroid hormone receptor beta mutant Delta337T alters peroxisome proliferator-activated receptor alpha signaling in heart. Am. J. Physiol. Endocrinol. Metab. 292: E453-E460 (2007). *
Burrage PS, Huntington JT, Sporn MB, Brinckerhoff CE. Regulation of matrix metalloproteinase gene expression by a retinoid X receptor-specific ligand. Arthritis Rheum. 56: 892-904 (2007). *
Burrage PS, Mix KS, Brinckerhoff CE. Matrix metalloproteinases: role in arthritis. Front. Biosci. 11: 529-543 (2006).
Burrage PS, Schmucker AC, Ren Y, Sporn MB, Brinckerhoff CE. Retinoid X receptor and peroxisome proliferator-activated receptor-gamma agonists cooperate to inhibit matrix metalloproteinase gene expression. Arthritis Res. Ther. 10: R139 (2008). *
Burrin DG, Stoll B. Emerging aspects of gut sulfur amino acid metabolism. Curr. Opin. Clin. Nutr. Metab. Care 10: 63-68 (2007).
Burt AD. Spectrum of liver pathology in immune mediated liver diseases. J. Gastroenterol. Hepatol. 19: S353-S355 (2004). *
Burum-Auensen E, De Angelis PM, Schjolberg AR, Roislien J, Andersen SN, Clausen OP. Spindle proteins Aurora A and BUB1B, but not Mad2, are aberrantly expressed in dysplastic mucosa of patients with longstanding ulcerative colitis. J. Clin. Pathol. 60: 1403-1408 (2007). *
Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A. Hum. Gene Ther. 17: 135-146 (2006).
Busso N, Frasnelli M, Feifel R, Cenni B, Steinhoff M, Hamilton J, So A. Evaluation of protease-activated receptor 2 in murine models of arthritis. Arthritis Rheum. 56: 101-107 (2007). *
Bustamante M, Nogues X, Agueda L, Jurado S, Wesselius A, Caceres E, Carreras R, Ciria M, Mellibovsky L, Balcells S, Diez-Perez A, Grinberg D. Promoter 2 -1025 T/C polymorphism in the RUNX2 gene is associated with femoral neck BMD in Spanish postmenopausal women. Calcif. Tissue Int. 81: 327-332 (2007). *
Butler JE, Moore MB, Presnell SR, Chan HW, Chalupny NJ, Lutz CT. Proteasome regulation of ULBP1 transcription. J. Immunol. 182: 6600-6609 (2009).
Butscheid M, Hauptvogel P, Fritz P, Klotz U, Alscher D. Hepatic expression of galectin-3 and receptor for advanced glycation end products in patients with liver disease. J. Clin. Pathol. 60: 415-418 (2007).
Butti E, Bergami A, Recchia A, Brambilla E, Del Carro U, Amadio S, Cattalini A, Esposito M, Stornaiuolo A, Comi G, Pluchino S, Mavilio F, Martino G, Furlan R. IL4 gene delivery to the CNS recruits regulatory T cells and induces clinical recovery in mouse models of multiple sclerosis. Gene Ther. 15: 504-515 (2008).
Butura A, Nilsson K, Morgan K, Morgan TR, French SW, Johansson I, Schuppe-Koistinen I, Ingelman-Sundberg M. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model. J. Hepatol. 50: 572-583 (2009).
Buxbaum JD, Georgieva L, Young JJ, Plescia C, Kajiwara Y, Jiang Y, Moskvina V, Norton N, Peirce T, Williams H, Craddock NJ, Carroll L, Corfas G, Davis KL, Owen MJ, Harroch S, Sakurai T, O'Donovan MC. Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene. Mol. Psychiatry 13: 162-172 (2008).
Buxbaum JN, Ye Z, Reixach N, Friske L, Levy C, Das P, Golde T, Masliah E, R Roberts A, Bartfai T. Transthyretin protects Alzheimer's mice from the behavioral and biochemical effects of Abeta toxicity. Proc. Natl. Acad. Sci. U.S.A. 105: 2681-2686 (2008). *
Buyon JP, Clancy RM, Friedman DM. Autoimmune associated congenital heart block: integration of clinical and research clues in the management of the maternal/foetal dyad at risk. J. Intern. Med. 265: 653-662 (2009).
Buyse M, Radeva G, Bado A, Farinotti R. Intestinal inflammation induces adaptation of P-glycoprotein expression and activity. Biochem. Pharmacol. 69: 1745-1754 (2005). *
Buzzelli MD, Nagarajan M, Radtka JF, Shumate ML, Navaratnarajah M, Lang CH, Cooney RN. Nuclear factor kappaB mediates the inhibitory effects of tumor necrosis factor-alpha on growth hormone-inducible gene expression in liver. Endocrinology 149: 6378-6388 (2008). *
Byrd JC, Bresalier RS. Mucins and mucin binding proteins in colorectal cancer. Cancer Metastasis Rev. 23: 77-99 (2004). *
Byrne JA, Meara NJ, Rayner AC, Thompson RJ, Knisely AS. Lack of hepatocellular CD10 along bile canaliculi is physiologic in early childhood and persistent in Alagille syndrome. Lab. Invest. 87: 1138-1148 (2007). *
Byun HJ, Jung WW, Lee JB, Chung HY, Sul D, Kim SJ, Park CG, Choi I, Hwang KW, Chun T. An evaluation of the neonatal immune system using a Listeria infection model. Neonatology 92: 83-90 (2007).
Caballero-Franco C, Keller K, De Simone C, Chadee K. The VSL#3 probiotic formula induces mucin gene expression and secretion in colonic epithelial cells. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G315-G322 (2007). *
Cabbage SE, Huseby ES, Sather BD, Brabb T, Liggitt D, Goverman J. Regulatory T cells maintain long-term tolerance to myelin basic protein by inducing a novel, dynamic state of T cell tolerance. J. Immunol. 178: 887-896 (2007). *
Cable EE, Finn PD, Stebbins JW, Hou J, Ito BR, van Poelje PD, Linemeyer DL, Erion MD. Reduction of hepatic steatosis in rats and mice after treatment with a liver-targeted thyroid hormone receptor agonist. Hepatology 49: 407-417 (2009).
Cabranes A, Venderova K, de Lago E, Fezza F, Sanchez A, Mestre L, Valenti M, Garcia-Merino A, Ramos JA, Di Marzo V, Fernandez-Ruiz J. Decreased endocannabinoid levels in the brain and beneficial effects of agents activating cannabinoid and/or vanilloid receptors in a rat model of multiple sclerosis. Neurobiol. Dis. 20: 207-217 (2005).
Cabrelle A, Dell'aica I, Melchiori L, Carraro S, Brunetta E, Niero R, Scquizzato E, D'Intino G, Calz L, Garbisa S, Agostini C. Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease. J. Leukoc. Biol. 83: 212-219 (2008). *
Cabrero A, Alegret M, Sanchez RM, Adzet T, Laguna JC, Vazquez M. Bezafibrate reduces mRNA levels of adipocyte markers and increases fatty acid oxidation in primary culture of adipocytes. Diabetes 50: 1883-1890 (2001). *
Cabrero A, Cubero M, Llaverias G, Jove M, Planavila A, Alegret M, Sanchez R, Laguna JC, Carrera MV. Differential effects of peroxisome proliferator-activated receptor activators on the mRNA levels of genes involved in lipid metabolism in primary human monocyte-derived macrophages. Metabolism 52: 652-657 (2003). *
Cabrero A, Laguna JC, Vazquez M. Peroxisome proliferator-activated receptors and the control of inflammation. Curr. Drug Targets Inflamm. Allergy 1: 243-248 (2002).
Cabrijan L, Lipozencic J, Batinac T, Lenkovic M, Stanic Zgombic Z. Influence of PUVA and UVB radiation on expression of ICAM-1 and VCAM-1 molecules in psoriasis vulgaris. Coll. Antropol. 32 Suppl. 2: 53-56 (2008).
Cacev T, Radosevic S, Spaventi R, Pavelic K, Kapitanovic S. NF1 gene loss of heterozygosity and expression analysis in sporadic colon cancer. Gut 54: 1129-1135 (2005). *
Cadoudal T, Glorian M, Massias A, Fouque F, Forest C, Benelli C. Retinoids upregulate phosphoenolpyruvate carboxykinase and glyceroneogenesis in human and rodent adipocytes. J. Nutr. 138: 1004-1009 (2008). *
Cadwell K, Liu JY, Brown SL, Miyoshi H, Loh J, Lennerz JK, Kishi C, Kc W, Carrero JA, Hunt S, Stone CD, Brunt EM, Xavier RJ, Sleckman BP, Li E, Mizushima N, Stappenbeck TS, Virgin Iv HW. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature 456: 259-263 (2008). *
Cadwell K, Patel KK, Komatsu M, Virgin HW 4th, Stappenbeck TS. A common role for Atg16L1, Atg5 and Atg7 in small intestinal Paneth cells and Crohn disease. Autophagy 5: 250-252 (2009).
Caglayan E, Stauber B, Collins AR, Lyon CJ, Yin F, Liu J, Rosenkranz S, Erdmann E, Peterson LE, Ross RS, Tangirala RK, Hsueh WA. Differential roles of cardiomyocyte and macrophage peroxisome proliferator-activated receptor gamma in cardiac fibrosis. Diabetes 57: 2470-2479 (2008). *
Cagnard N, Letourneur F, Essabbani A, Devauchelle V, Mistou S, Rapinat A, Decraene C, Fournier C, Chiocchia G. Interleukin-32, CCL2, PF4F1 and GFD10 are the only cytokine/chemokine genes differentially expressed by in vitro cultured rheumatoid and osteoarthritis fibroblast-like synoviocytes. Eur. Cytokine Netw. 16: 289-292 (2005).
Cagnin A, Taylor-Robinson SD, Forton DM, Banati RB. In vivo imaging of cerebral "peripheral benzodiazepine binding sites" in patients with hepatic encephalopathy. Gut 55: 547-553 (2006). *
Cagnin S, Biscuola M, Patuzzo C, Trabetti E, Pasquali A, Laveder P, Faggian G, Iafrancesco M, Mazzucco A, Pignatti PF, Lanfranchi G. Reconstruction and functional analysis of altered molecular pathways in human atherosclerotic arteries. BMC Genomics 10: 13 (2009). *
Cahan P, Li Y, Izumi M, Graubert TA. The impact of copy number variation on local gene expression in mouse hematopoietic stem and progenitor cells. Nat. Genet. 41: 430-437 (2009). *
Cahill RJ, Foltz CJ, Fox JG, Dangler CA, Powrie F, Schauer DB. Inflammatory bowel disease: an immunity-mediated condition triggered by bacterial infection with Helicobacter hepaticus. Infect. Immun. 65: 3126-3131 (1997). *
Cai G, Zhang J, Liu L, Shen Q. Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA. J. Mol. Cell. Cardiol. 38: 593-605 (2005). *
Cai H, Chen L, Wan L, Zeng L, Yang H, Li S, Li Y, Cheng J, Lu X. High-level expression of a functional humanized anti-CTLA4 single-chain variable fragment antibody in Pichia pastoris. Appl. Microbiol. Biotechnol. 82: 41-48 (2009). *
Cai L, Yin JP, Starovasnik MA, Hogue DA, Hillan KJ, Mort JS, Filvaroff EH. Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo. Cytokine 16: 10-21 (2001).
Cai SY, Boyer JL. FXR: a target for cholestatic syndromes? Expert Opin. Ther. Targets 10: 409-421 (2006).
Cai SY, Gautam S, Nguyen T, Soroka CJ, Rahner C, Boyer JL. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained. Gastroenterology 136: 1060-1069.e4 (2009). *
Cai SY, Wang L, Ballatori N, Boyer JL. Bile salt export pump is highly conserved during vertebrate evolution and its expression is inhibited by PFIC type II mutations. Am. J. Physiol. Gastrointest. Liver Physiol. 281: G316-G322 (2001). *
Cai X, Wong YF, Zhou H, Xie Y, Liu ZQ, Jiang ZH, Bian ZX, Xu HX, Liu L. The comparative study of Sprague-Dawley and Lewis rats in adjuvant-induced arthritis. Naunyn. Schmiedebergs. Arch. Pharmacol. 373: 140-147 (2006). *
Cai Y, Dai T, Ao Y, Konishi T, Chuang KH, Lue Y, Chang C, Wan YJ. Cytochrome P450 genes are differentially expressed in female and male hepatocyte retinoid X receptor alpha-deficient mice. Endocrinology 144: 2311-2318 (2003). *
Cai Y, Konishi T, Han G, Campwala KH, French SW, Wan YJ. The role of hepatocyte RXR alpha in xenobiotic-sensing nuclear receptor-mediated pathways. Eur. J. Pharm. Sci. 15: 89-96 (2002). *
Calabrese V, Butterfield DA, Stella AM. Nutritional antioxidants and the heme oxygenase pathway of stress tolerance: novel targets for neuroprotection in Alzheimer's disease. Ital. J. Biochem. 52: 177-181 (2003).
Calabrese V, Cornelius C, Mancuso C, Pennisi G, Calafato S, Bellia F, Bates TE, Giuffrida Stella AM, Schapira T, Dinkova Kostova AT, Rizzarelli E. Cellular stress response: a novel target for chemoprevention and nutritional neuroprotection in aging, neurodegenerative disorders and longevity. Neurochem. Res. 33: 2444-2471 (2008).
Calabrese V, Lodi R, Tonon C, D'Agata V, Sapienza M, Scapagnini G, Mangiameli A, Pennisi G, Stella AM, Butterfield DA. Oxidative stress, mitochondrial dysfunction and cellular stress response in Friedreich's ataxia. J. Neurol. Sci. 233: 145-162 (2005). *
Calabrese V, Scapagnini G, Colombrita C, Ravagna A, Pennisi G, Giuffrida Stella AM, Galli F, Butterfield DA. Redox regulation of heat shock protein expression in aging and neurodegenerative disorders associated with oxidative stress: a nutritional approach. Amino Acids 25: 437-444 (2003). *
Calabuig E, Salavert M. Infectious risk. Actas Dermosifiliogr. 99 Suppl. 4: 14-22 (2008).
Calandria JM, Marcheselli VL, Mukherjee PK, Uddin J, Winkler JW, Petasis NA, Bazan NG. Selective survival rescue in 15-lipoxygenase-1 deficient retinal pigment epithelial cells by the novel docosahexaenoic acid-derived mediator, neuroprotectin D1. J. Biol. Chem. Apr 29 [Epub ahead of print] (2009). *
Calbo S, Delagreverie H, Arnoult C, Authier FJ, Tron F, Boyer O. Functional tolerance of CD8+ T cells induced by muscle-specific antigen expression. J. Immunol. 181: 408-417 (2008).
Calcagno AM, Ludwig JA, Fostel JM, Gottesman MM, Ambudkar SV. Comparison of drug transporter levels in normal colon, colon cancer, and Caco-2 cells: impact on drug disposition and discovery. Mol. Pharm. 3: 87-93 (2006).
Calcinaro F, Dionisi S, Marinaro M, Candeloro P, Bonato V, Marzotti S, Corneli RB, Ferretti E, Gulino A, Grasso F, De Simone C, Di Mario U, Falorni A, Boirivant M, Dotta F. Oral probiotic administration induces interleukin-10 production and prevents spontaneous autoimmune diabetes in the non-obese diabetic mouse. Diabetologia 48: 1565-1575 (2005). *
Caldenhoven E, Liden J, Wissink S, Van de Stolpe A, Raaijmakers J, Koenderman L, Okret S, Gustafsson JA, Van der Saag PT. Negative cross-talk between RelA and the glucocorticoid receptor: a possible mechanism for the antiinflammatory action of glucocorticoids. Mol. Endocrinol. 9: 401-412 (1995). *
Calder PC. Polyunsaturated fatty acids and inflammatory processes: new twists in an old tale. Biochimie. 91: 791-795 (2009).
Calder PC. Fatty acids and gene expression related to inflammation. Nestle Nutr. Workshop Ser. Clin. Perform. Programme 7: 19-36 (2002).
Calder PC. Immunoregulatory and anti-inflammatory effects of n-3 polyunsaturated fatty acids. Braz. J. Med. Biol. Res. 31: 467-490 (1998). *
Calder PC. Dietary modification of inflammation with lipids. Proc. Nutr. Soc. 61: 345-358 (2002). *
Calder PC. n-3 Polyunsaturated fatty acids and inflammation: from molecular biology to the clinic. Lipids 38: 343-352 (2003).
Calder PC. Polyunsaturated fatty acids and inflammation. Biochem. Soc. Trans. 33: 423-427 (2005). *
Calder PC. Polyunsaturated fatty acids, inflammatory processes and inflammatory bowel diseases. Mol. Nutr. Food Res. 52: 885-897 (2008). *
Calder PC, Dimitriadis G, Newsholme P. Glucose metabolism in lymphoid and inflammatory cells and tissues. Curr. Opin. Clin. Nutr. Metab. Care 10: 531-540 (2007).
Calder PC, Yaqoob P. Omega-3 polyunsaturated fatty acids and human health outcomes. Biofactors 35: 266-272 (2009).
Calderon B, Suri A, Pan XO, Mills JC, Unanue ER. IFN-gamma-dependent regulatory circuits in immune inflammation highlighted in diabetes. J. Immunol. 181: 6964-6974 (2008).
Calderon TM, Eugenin EA, Lopez L, Kumar SS, Hesselgesser J, Raine CS, Berman JW. A role for CXCL12 (SDF-1alpha) in the pathogenesis of multiple sclerosis: regulation of CXCL12 expression in astrocytes by soluble myelin basic protein. J. Neuroimmunol. 177: 27-39 (2006).
Callen DF, Baker E, Simmers RN, Seshadri R, Roninson IB. Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. Hum. Genet. 77: 142-144 (1987).
Calmus Y, Gane P, Rouger P, Poupon R. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid. Hepatology 11: 12-15 (1990).
Calon F, Lim GP, Morihara T, Yang F, Ubeda O, Salem N Jr, Frautschy SA, Cole GM. Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease. Eur. J. Neurosci. 22: 617-626 (2005). *
Cals-Grierson MM, Ormerod AD. Nitric oxide function in the skin. Nitric Oxide 10: 179-193 (2004). *
Calura E, Cagnin S, Raffaello A, Laveder P, Lanfranchi G, Romualdi C. Meta-analysis of expression signatures of muscle atrophy: gene interaction networks in early and late stages. BMC Genomics 9: 630 (2008). *
Calvano SE, Xiao W, Richards DR, Felciano RM, Baker HV, Cho RJ, Chen RO, Brownstein BH, Cobb JP, Tschoeke SK, Miller-Graziano C, Moldawer LL, Mindrinos MN, Davis RW, Tompkins RG, Lowry SF, Large Scale Collab Res Program IA. A network-based analysis of systemic inflammation in humans. Nature 437: 1032-1037 (2005). *
Calverley DC, Baldermann LV, Moran K, Chen NN, McFann K. Platelet FcgammaRIIA expression is associated with the alpha(2) integrin C807T gene polymorphism in type 2 diabetes. Platelets 17: 78-83 (2006).
Calviello G, Di Nicuolo F, Gragnoli S, Piccioni E, Serini S, Maggiano N, Tringali G, Navarra P, Ranelletti FO, Palozza P. n-3 PUFAs reduce VEGF expression in human colon cancer cells modulating the COX-2/PGE2 induced ERK-1 and -2 and HIF-1alpha induction pathway. Carcinogenesis 25: 2303-2310 (2004). *
Calviello G, Resci F, Serini S, Piccioni E, Toesca A, Boninsegna A, Monego G, Ranelletti FO, Palozza P. Docosahexaenoic acid induces proteasome-dependent degradation of beta-catenin, down-regulation of survivin and apoptosis in human colorectal cancer cells not expressing COX-2. Carcinogenesis 28: 1202-1209 (2007). *
Calvisi DF, Ladu S, Hironaka K, Factor VM, Thorgeirsson SS. Vitamin E down-modulates iNOS and NADPH oxidase in c-Myc/TGF-alpha transgenic mouse model of liver cancer. J. Hepatol. 41: 815-822 (2004). *
Calvisi DF, Pinna F, Ladu S, Pellegrino R, Simile MM, Frau M, De Miglio MR, Tomasi ML, Sanna V, Muroni MR, Feo F, Pascale RM. Forkhead box M1B is a determinant of rat susceptibility to hepatocarcinogenesis and sustains ERK activity in human HCC. Gut 58: 679-687 (2009).
Calzascia T, Loh JM, Di Berardino-Besson W, Masson F, Guillaume P, Burkhardt K, Herrera PL, Dietrich PY, Walker PR. Peripheral tolerance limits CNS accumulation of CD8 T cells specific for an antigen shared by tumor cells and normal astrocytes. Glia 56: 1625-1636 (2008).
Camacho JA, Mardach R, Rioseco-Camacho N, Ruiz-Pesini E, Derbeneva O, Andrade D, Zaldivar F, Qu Y, Cederbaum SD. Clinical and functional characterization of a human ORNT1 mutation (T32R) in the hyperornithinemia-hyperammonemia-homocitrullinuria (HHH) syndrome. Pediatr. Res. 60: 423-429 (2006). *
Camacho M, Rodriguez C, Salazar J, Martinez-Gonzalez J, Ribalta J, Escudero JR, Masana L, Vila L. Retinoic acid induces PGI-synthase expression in human endothelial cells. J. Lipid Res. 49: 1707-1714 (2008). *
Camacho-Barquero L, Villegas I, Sanchez-Calvo JM, Talero E, Sanchez-Fidalgo S, Motilva V, Alarcon de la Lastra C. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. Int. Immunopharmacol. 7: 333-342 (2007).
Camateros P, Moisan J, Henault J, De Sanctis J, Skamene E, Radzioch D. Toll-like receptors, cytokines and the immunotherapeutics of asthma. Curr. Pharm. Des. 12: 2365-2374 (2006).
Camateros P, Tamaoka M, Hassan M, Marino R, Moisan J, Marion D, Guiot MC, Martin JG, Radzioch D. Chronic asthma induced airway remodeling is prevented by the Toll-like receptor 7/8 ligand S28463. Am. J. Respir. Crit. Care Med. 175: 1241-1249 (2007). *
Cameron ER, Neil JC. The Runx genes: lineage-specific oncogenes and tumor suppressors. Oncogene 23: 4308-4314 (2004). *
Cameron S, Haller F, Dudas J, Moriconi F, Gunawan B, Armbrust T, Langer C, F�zesi L, Ramadori G. Immune cells in primary gastrointestinal stromal tumors. Eur. J. Gastroenterol. Hepatol. 20: 327-334 (2008).
Camilleri M, Carlson P, McKinzie S, Grudell A, Busciglio I, Burton D, Baxter K, Ryks M, Zinsmeister AR. Genetic variation in endocannabinoid metabolism, gastrointestinal motility and sensation. Am. J. Physiol. Gastrointest. Liver Physiol. 294: G13-G19 (2008). *
Camoglio L, Te Velde AA, Tigges AJ, Das PK, Van Deventer SJ. Altered expression of interferon-gamma and interleukin-4 in inflammatory bowel disease. Inflamm. Bowel Dis. 4: 285-290 (1998). *
Campagna D, Cope L, Lakkur SS, Henderson C, Laheru D, Iacobuzio-Donahue CA. Gene expression profiles associated with advanced pancreatic cancer. Int. J. Clin. Exp. Pathol. 1: 32-43 (2008). *
Campagnoli MF, Pucci A, Garelli E, Carando A, Defilippi C, Lala R, Ingrosso G, Dianzani I, Forni M, Ramenghi U. Familial tumoral calcinosis and testicular microlithiasis associated with a new mutation of GALNT3 in a white family. J. Clin. Pathol. 59: 440-442 (2006). *
Campana G, Pasini P, Roda A, Spampinato S. Regulation of ileal bile acid-binding protein expression in Caco-2 cells by ursodeoxycholic acid: role of the farnesoid X receptor. Biochem. Pharmacol. 69: 1755-1763 (2005). *
Campanati A, Goteri G, Simonetti O, Ganzetti G, Giuliodori K, Giuliano A, Sabato S, Stramazzotti D, Gulini E, Dusi D, De Blasio S, Fabris G, Offidani A. Angiogenesis in psoriatic skin and its modifications after administration of etanercept: videocapillaroscopic, histological and immunohistochemical evaluation. Int. J. Immunopathol. Pharmacol. 22: 371-377 (2009).
Campbell DB, Buie TM, Winter H, Bauman M, Sutcliffe JS, Perrin JM, Levitt P. Distinct genetic risk based on association of MET in families with co-occurring autism and gastrointestinal conditions. Pediatrics 123: 1018-1024 (2009). *
Campbell DB, D'Oronzio R, Garbett K, Ebert PJ, Mirnics K, Levitt P, Persico AM. Disruption of cerebral cortex MET signaling in autism spectrum disorder. Ann. Neurol. 62: 243-250 (2007).
Campbell DB, Sutcliffe JS, Ebert PJ, Militerni R, Bravaccio C, Trillo S, Elia M, Schneider C, Melmed R, Sacco R, Persico AM, Levitt P. A genetic variant that disrupts MET transcription is associated with autism. Proc. Natl. Acad. Sci. U.S.A. 103: 16834-16839 (2006). *
Campbell DJ, Ziegler SF. FOXP3 modifies the phenotypic and functional properties of regulatory T cells. Nat. Rev. Immunol. 7: 305-310 (2007). *
Campbell IK, Kinkel SA, Drake SF, Nieuwenhuijze AV, Hubert FX, Tarlinton DM, Heath WR, Scott HS, Wicks IP. Autoimmune regulator controls T cell help for pathogenetic autoantibody production in collagen-induced arthritis. Arthritis Rheum. 60: 1683-1693 (2009). *
Campbell JJ, Murphy KE, Kunkel EJ, Brightling CE, Soler D, Shen Z, Boisvert J, Greenberg HB, Vierra MA, Goodman SB, Genovese MC, Wardlaw AJ, Butcher EC, Wu L. CCR7 expression and memory T cell diversity in humans. J. Immunol. 166: 877-884 (2001). *
Campbell JS, Hughes SD, Gilbertson DG, Palmer TE, Holdren MS, Haran AC, Odell MM, Bauer RL, Ren HP, Haugen HS, Yeh MM, Fausto N. Platelet-derived growth factor C induces liver fibrosis, steatosis, and hepatocellular carcinoma. Proc. Natl. Acad. Sci. U.S.A. 102: 3389-3394 (2005). *
Campbell KL, Makar KW, Kratz M, Foster-Schubert KE, McTiernan A, Ulrich CM. A pilot study of sampling subcutaneous adipose tissue to examine biomarkers of cancer risk. Cancer Prev. Res. (Phila. Pa) 2: 37-42 (2009).
Campbell PW 3rd, Phillips JA 3rd. The cystic fibrosis gene and relationships to clinical status. Semin. Respir. Infect. 7: 150-157 (1992).
Campbell S, Michaelson J, Burkly L, Putterman C. The role of TWEAK/Fn14 IN the pathogenesis of inflammation and systemic autoimmunity. Front. Biosci. 9: 2273-2284 (2004).
Campese AF, Grazioli P, Colantoni S, Anastasi E, Mecarozzi M, Checquolo S, De Luca G, Bellavia D, Frati L, Gulino A, Screpanti I. Notch3 and pTalpha/pre-TCR sustain the in vivo function of naturally occurring regulatory T cells. Int. Immunol. 21: 727-743 (2009).
Campo GM, Avenoso A, Campo S, D'Ascola A, Traina P, Sama D, Calatroni A. Glycosaminoglycans modulate inflammation and apoptosis in LPS-treated chondrocytes. J. Cell. Biochem. 106: 83-92 (2009). *
Campo I, Morbini P, Zorzetto M, Tinelli C, Brunetta E, Villa C, Bombieri C, Cuccia M, Agostini C, Bozzi V, Facoetti A, Ferrarotti I, Mazzola P, Scabini R, Semenzato G, Pignatti PF, Pozzi E, Luisetti M. Expression of receptor for advanced glycation end products in sarcoid granulomas. Am. J. Respir. Crit. Care Med. 175: 498-506 (2007). *
Campoli M, Ferrone S. Tumor escape mechanisms: potential role of soluble HLA antigens and NK cells activating ligands. Tissue Antigens 72: 321-334 (2008). *
Canale-Zambrano JC, Poffenberger MC, Cory SM, Humes DG, Haston CK. Intestinal phenotype of variable-weight cystic fibrosis knockout mice. Am. J. Physiol. Gastrointest. Liver Physiol. 293: G222-G229 (2007). *
Canaple L, Rambaud J, Dkhissi-Benyahya O, Rayet B, Tan NS, Michalik L, Delaunay F, Wahli W, Laudet V. Reciprocal regulation of BMAL1 and PPARalpha defines a novel positive feedback loop in the rodent liver circadian clock. Mol. Endocrinol. 20: 1715-1727 (2006). *
Canbay A, Feldstein A, Baskin-Bey E, Bronk SF, Gores GJ. The caspase inhibitor IDN-6556 attenuates hepatic injury and fibrosis in the bile duct ligated mouse. J. Pharmacol. Exp. Ther. 308: 1191-1196 (2004). *
Cancino-Diaz JC, Reyes-Maldonado E, Banuelos-Panuco CA, Jimenez-Zamudio L, Garcia-Latorre E, Leon-Dorantes G, Blancas-Gonzalez F, Paredes-Cabrera G, Cancino-Diaz ME. Interleukin-13 receptor in psoriatic keratinocytes: overexpression of the mRNA and underexpression of the protein. J. Invest. Dermatol. 119: 1114-1120 (2002). *
Cane G, Moal VL, Pages G, Servin AL, Hofman P, Vouret-Craviari V. Up-regulation of intestinal vascular endothelial growth factor by Afa/Dr diffusely adhering Escherichia coli. PLoS ONE 2: e1359 (2007). *
Canedo P, Corso G, Pereira F, Lunet N, Suriano G, Figueiredo C, Pedrazzani C, Moreira H, Barros H, Carneiro F, Seruca R, Roviello F, Machado JC. The interferon gamma receptor 1 (IFNGR1) -56C/T gene polymorphism is associated with increased risk of early gastric carcinoma. Gut 57: 1504-1508 (2008).
Canestro C, Catchen JM, Rodriguez-Mari A, Yokoi H, Postlethwait JH. Consequences of lineage-specific gene loss on functional evolution of surviving paralogs: ALDH1A and retinoic acid signaling in vertebrate genomes. PLoS Genet. 5: e1000496 (2009). *
Canete JD, Santiago B, Cantaert T, Sanmarti R, Palacin A, Celis R, Graell E, Gil-Torregrosa B, Baeten D, Pablos JL. Ectopic lymphoid neogenesis in psoriatic arthritis. Ann. Rheum. Dis. 66: 720-726 (2007). *
Canny G, Cario E, Lennartsson A, Gullberg U, Brennan C, Levy O, Colgan SP. Functional and biochemical characterization of epithelial bactericidal/permeability-increasing protein. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G557-G567 (2006). *
Canny G, Colgan SP. Events at the host-microbial interface of the gastrointestinal tract. I. Adaptation to a microbial world: role of epithelial bactericidal/permeability-increasing protein. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G593-G597 (2005). *
Cansell MS, Battin A, Degrace P, Gresti J, Clouet P, Combe N. Early dissimilar fates of liver eicosapentaenoic acid in rats fed liposomes or fish oil and gene expression related to lipid metabolism. Lipids 44: 237-247 (2009).
Cantarini MC, de la Monte SM, Pang M, Tong M, D'Errico A, Trevisani F, Wands JR. Aspartyl-asparagyl beta hydroxylase over-expression in human hepatoma is linked to activation of insulin-like growth factor and notch signaling mechanisms. Hepatology 44: 446-457 (2006). *
Cantin AM, Bilodeau G, Ouellet C, Liao J, Hanrahan JW. Oxidant stress suppresses CFTR expression. Am. J. Physiol. Cell. Physiol. 290: C262-C270 (2006). *
Cantin AM, Hanrahan JW, Bilodeau G, Ellis L, Dupuis A, Liao J, Zielenski J, Durie P. Cystic fibrosis transmembrane conductance regulator function is suppressed in cigarette smokers. Am. J. Respir. Crit. Care Med. 173: 1139-1144 (2006). *
Canto E, Rodriguez-Sanchez JL, Vidal S. Naive CD4+ cells from cord blood can generate competent Th effector cells. Transplantation 80: 850-858 (2005).
Canton RF, Peijnenburg AA, Hoogenboom RL, Piersma AH, van der Ven LT, van den Berg M, Heneweer M. Subacute effects of hexabromocyclododecane (HBCD) on hepatic gene expression profiles in rats. Toxicol. Appl. Pharmacol. 231: 267-272 (2008). *
Cantorna MT, Nashold FE, Hayes CE. Vitamin A deficiency results in a priming environment conducive for Th1 cell development. Eur. J. Immunol. 25: 1673-1679 (1995).
Cany J, Avril A, Pichard V, Aubert D, Ferry N, Conchon S. A transgenic mouse with beta-galactosidase as a fetal liver self-antigen for immunotherapy studies. J. Hepatol. 47: 396-403 (2007). *
Cao G, Bales KR, Demattos RB, Paul SM. Liver X receptor-mediated gene regulation and cholesterol homeostasis in brain: relevance to Alzheimer's disease therapeutics. Curr. Alzheimer Res. 4: 179-184 (2007).
Cao G, Beyer TP, Yang XP, Schmidt RJ, Zhang Y, Bensch WR, Kauffman RF, Gao H, Ryan TP, Liang Y, Eacho PI, Jiang XC. Phospholipid transfer protein is regulated by liver X receptors in vivo. J. Biol. Chem. 277: 39561-39565 (2002). *
Cao H, Kabaroff LC, You Q, Rodriguez A, Boermans HJ, Karrow NA. Characterization of ovine hepatic gene expression profiles in response to Escherichia coli lipopolysaccharide using a bovine cDNA microarray. BMC Vet. Res. 2: 34 (2006). *
Cao H, Liu H, Wu ZY. Effects of combined immune therapy on survival and Th1/Th2 cytokine balance in rat orthotopic liver transplantation. Chin. Med. J. (Engl.) 120: 1809-1812 (2007).
Cao J, Li JL, Li D, Tobin JF, Gimeno RE. Molecular identification of microsomal acyl-CoA:glycerol-3-phosphate acyltransferase, a key enzyme in de novo triacylglycerol synthesis. Proc. Natl. Acad. Sci. U.S.A. 103: 19695-19700 (2006). *
Cao L, Xu X, Cao LL, Wang RH, Coumoul X, Kim SS, Deng CX. Absence of full-length Brca1 sensitizes mice to oxidative stress, and carcinogen-induced tumorigenesis in the esophagus and forestomach. Carcinogenesis 28: 1401-1407 (2007). *
Cao LQ, Chen XL, Wang Q, Huang XH, Zhen MC, Zhang LJ, Li W, Bi J. Upregulation of PTEN involved in rosiglitazone-induced apoptosis in human hepatocellular carcinoma cells. Acta Pharmacol. Sin. 28: 879-887 (2007). *
Cao M, Cao P, Yan H, Lu W, Ren F, Hu Y, Zhang S. Construction, purification, and characterization of anti-BAFF scFv-Fc fusion antibody expressed in CHO/dhfr(-) cells. Appl. Biochem. Biotechnol. 157: 562-574 (2009). *
Cao P, Zhang S, Fang Z, Huang H, Bai P, Zhang Q, Luo C. Generation of a fusion protein of the extracellular domain of BR3 with the Fc fragment of human IgG1 (sBR3-Fc) in Pichia pastoris as an antagonist for BLyS. Appl. Microbiol. Biotechnol. 78: 275-282 (2008). *
Cao WM, Murao K, Imachi H, Yu X, Dobashi H, Yoshida K, Muraoka T, Kotsuna N, Nagao S, Wong NC, Ishida T. Insulin like growth factor-I regulation of hepatic scavenger receptor class BI. Endocrinology 145: 5540-5547 (2004). *
Cao Y, Brombacher F, Tunyogi-Csapo M, Glant TT, Finnegan A. Interleukin-4 regulates proteoglycan-induced arthritis by specifically suppressing the innate immune response. Arthritis Rheum. 56: 861-870 (2007). *
Capeau J. The story of adiponectin and its receptors AdipoR1 and R2: to follow. J. Hepatol. 47: 736-738 (2007).
Capelli A, Di Stefano A, Gnemmi I, Donner CF. CCR5 expression and CC chemokine levels in idiopathic pulmonary fibrosis. Eur. Respir. J. 25: 701-707 (2005). *
Capello A, Moons LM, Van de Winkel A, Siersema PD, van Dekken H, Kuipers EJ, Kusters JG. Bile acid-stimulated expression of the farnesoid X receptor enhances the immune response in Barrett esophagus. Am. J. Gastroenterol. 103: 1510-1516 (2008). *
Capocasale RJ, Makropoulos DA, Achuthanandam R, Stowell N, Quinn J, Rafferty PA, O'Brien J, Emmell E, Bugelski PJ. Myelodysplasia and anemia of chronic disease in human tumor necrosis factor-alpha transgenic mice. Cytometry A. 73: 148-159 (2008).
Capon F, Allen MH, Ameen M, Burden AD, Tillman D, Barker JN, Trembath RC. A synonymous SNP of the corneodesmosin gene leads to increased mRNA stability and demonstrates association with psoriasis across diverse ethnic groups. Hum. Mol. Genet. 13: 2361-2368 (2004). *
Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. Hum. Mol. Genet. 17: 1938-1945 (2008). *
Caponi L, Petit-Teixeira E, Sebbag M, Bongiorni F, Moscato S, Pratesi F, Pierlot C, Osorio J, Chapuy-Regaud S, Guerrin M, Cornelis F, Serre G, Migliorini P; ECRAF. A family based study shows no association between rheumatoid arthritis and the PADI4 gene in a white French population. Ann. Rheum. Dis. 64: 587-593 (2005). *
Caprioli F, Pallone F, Monteleone G. Th17 immune response in IBD: a new pathogenic mechanism. Journal of Crohn's and Colitis 2: 291-295 (2008).
Caprioli F, Sarra M, Caruso R, Stolfi C, Fina D, Sica G, Macdonald TT, Pallone F, Monteleone G. Autocrine regulation of IL-21 production in human T lymphocytes. J. Immunol. 180: 1800-1807 (2008). *
Capsoni F, Sarzi-Puttini P, Atzeni F, Minonzio F, Bonara P, Doria A, Carrabba M. Effect of adalimumab on neutrophil function in patients with rheumatoid arthritis. Arthritis Res. Ther. 7: R250-R255 (2005). *
Capuano P, Bacic D, Stange G, Hernando N, Kaissling B, Pal R, Kocher O, Biber J, Wagner CA, Murer H. Expression and regulation of the renal Na/phosphate cotransporter NaPi-IIa in a mouse model deficient for the PDZ protein PDZK1. Pflugers Arch. 449: 392-402 (2005). *
Caputo CB, Salama AI. The amyloid proteins of Alzheimer's disease as potential targets for drug therapy. Neurobiol. Aging 10: 451-461 (1989).
Caputo M, Eletto D, Torino G, Tecce MF. Cooperation of docosahexaenoic acid and vitamin E in the regulation of UDP-glucuronosyltransferase mRNA expression. J. Cell Physiol. 215: 765-770 (2008). *
Caraccio N, Cuccato S, Pratesi F, Dardano A, Ursino S, Chimenti D, Boldrini L, Materazzi G, Migliorini P, Monzani F. Effect of type I interferon(s) on cell viability and apoptosis in primary human thyrocyte cultures. Thyroid 19: 149-155 (2009).
Caraceni P, Pertosa A, Giannone F, Domenicali M, Grattagliano I, Perrelli MG, Principe A, Cutrin J, Croci T, Bernardi M. Antagonism of the cannabinoid CB-1 receptor protects rat liver against ischemia-reperfusion injury complicated by endotoxemia. Gut Mar 11 [Epub ahead of print] (2009).
Caramia G. Omega-3: from cod-liver oil to nutrigenomics. Minerva Pediatr. 60: 443-455 (2008).
Carayol N, Chen J, Yang F, Jin T, Jin L, States D, Wang CY. A dominant function of IKK/NF-kappaB signaling in global lipopolysaccharide-induced gene expression. J. Biol. Chem. 281: 31142-31151 (2006). *
Carbone J, Sarmiento E, Micheloud D, Rodriguez-Molina J, Fernandez-Cruz E. Elevated levels of activated CD4 T cells in common variable immunodeficiency: association with clinical findings. Allergol. Immunopathol. (Madr.) 34: 131-135 (2006).
Cardoso CR, Provinciatto PR, Godoi DF, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. IL-4 regulates susceptibility to intestinal inflammation in murine food allergy. Am. J. Physiol. Gastrointest. Liver Physiol. 296: G593-G600 (2009). *
Cardoso CR, Provinciatto PR, Godoi DF, Vieira TS, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. B cells are involved in the modulation of pathogenic gut immune response in food-allergic enteropathy. Clin. Exp. Immunol. 154: 153-161 (2008).
Cardoso FC, Macedo GC, Gava E, Kitten GT, Mati VL, de Melo AL, Caliari MV, Almeida GT, Venancio TM, Verjovski-Almeida S, Oliveira SC. Schistosoma mansoni tegument protein Sm29 is able to induce a Th1-type of immune response and protection against parasite infection. PLoS Negl. Trop. Dis. 2: e308 (2008). *
Carey AH, Waterworth D, Patel K, White D, Little J, Novelli P, Franks S, Williamson R. Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum. Mol. Genet. 3: 1873-1876 (1994).
Carey AL, Petersen EW, Bruce CR, Southgate RJ, Pilegaard H, Hawley JA, Pedersen BK, Febbraio MA. Discordant gene expression in skeletal muscle and adipose tissue of patients with type 2 diabetes: effect of interleukin-6 infusion. Diabetologia 49: 1000-1007 (2006). *
Carey HV, Martin SL. Preservation of intestinal gene expression during hibernation. Am. J. Physiol. 271: G804-G813 (1996).
Carey R, Jurickova I, Ballard E, Bonkowski E, Han X, Xu H, Denson LA. Activation of an IL-6:STAT3-dependent transcriptome in pediatric-onset inflammatory bowel disease. Inflamm. Bowel Dis. 14: 446-457 (2008). *
Cariello NF, Romach EH, Colton HM, Ni H, Yoon L, Falls JG, Casey W, Creech D, Anderson SP, Benavides GR, Hoivik DJ, Brown R, Miller RT. Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver. Toxicol. Sci. 88: 250-264 (2005). *
Cario E. Toll-like receptors and gastrointestinal diseases: from bench to bedside? Curr. Opin. Gastroenterol. 18: 696-704 (2002).
Cario E, Podolsky DK. Differential alteration in intestinal epithelial cell expression of Toll-like receptor 3 (TLR3) and TLR4 in inflammatory bowel disease. Infect. Immun. 68: 7010-7017 (2000). *
Cariou B, Bouchaert E, Abdelkarim M, Dumont J, Caron S, Fruchart JC, Burcelin R, Kuipers F, Staels B. FXR-deficiency confers increased susceptibility to torpor. FEBS Lett. 581: 5191-5198 (2007). *
Carissimi C, Fulci V, Macino G. MicroRNAs: novel regulators of immunity. Autoimmun. Rev. 8: 520-524 (2009).
Carl JW, Bai XF. IL27: its roles in the induction and inhibition of inflammation. Int. J. Clin. Exp. Pathol. 1: 117-123 (2008). *
Carl VS, Brown-Steinke K, Nicklin MJ, Smith MF Jr. Toll-like receptor 2 and 4 (TLR2 and TLR4) agonists differentially regulate secretory interleukin-1 receptor antagonist gene expression in macrophages. J. Biol. Chem. 277: 17448-17456 (2002). *
Carlberg C, Dunlop TW. The impact of chromatin organization of vitamin D target genes. Anticancer Res. 26: 2637-2645 (2006).
Carlberg C, Dunlop TW. An integrated biological approach to nuclear receptor signaling in physiological control and disease. Crit. Rev. Eukaryot. Gene Expr. 16: 1-22 (2006).
Carlen L, Sakuraba K, Stahle M, Sanchez F. HLA-C expression pattern is spatially different between psoriasis and eczema skin lesions. J. Invest. Dermatol. 127: 342-348 (2007). *
Carlen LM, Sanchez F, Bergman AC, Becker S, Hirschberg D, Franzen B, Coffey J, Jornvall H, Auer G, Alaiya AA, Stahle M. Proteome analysis of skin distinguishes acute guttate from chronic plaque psoriasis. J. Invest. Dermatol. 124: 63-69 (2005). *
Carless M. Investigation of genomic methylation status using methylation-specific and bisulfite sequencing polymerase chain reaction. Methods Mol. Biol. 523: 1-18 (2009).
Carlos Moraes Dos Santos D, da Silva Gomes Martinho JM, Pacheco-Moreira LF, Carvalho Viana de Araujo C, Caroli-Bottino A, Pannain VL, Soares Trinta K, Gandini M, da Costa Neves PC, de Souza Matos DC, Goncalves Caputo LF, Pelajo-Machado M, Alves Pinto M. Eosinophils involved in fulminant hepatic failure are associated with high interleukin-6 expression and absence of interleukin-5 in liver and peripheral blood. Liver Int. 29: 544-551 (2009). *
Carlsen M, Cilio CM. Normal T cell development in the absence of thymic insulin expression. Ann. N. Y. Acad. Sci. 1079: 205-212 (2006). *
Carlson CS, Heagerty PJ, Nord AS, Pritchard DK, Ranchalis J, Boguch JM, Duan H, Hatsukami TS, Schwartz SM, Rieder MJ, Nickerson DA, Jarvik GP. TagSNP evaluation for the association of 42 inflammation loci and vascular disease: evidence of IL6, FGB, ALOX5, NFKBIA, and IL4R loci effects. Hum. Genet. 121: 65-75 (2007). *
Carluccio MA, Ancora MA, Massaro M, Carluccio M, Scoditti E, Distante A, Storelli C, De Caterina R. Homocysteine induces VCAM-1 gene expression through NF-kappaB and NAD(P)H oxidase activation - protective role of Mediterranean diet polyphenolic antioxidants. Am. J. Physiol. Heart Circ. Physiol. 293: H2344-H2354 (2007). *
Carmel JF, Tarnus E, Cohn JS, Bourdon E, Davignon J, Bernier L. High expression of apolipoprotein E impairs lipid storage and promotes cell proliferation in human adipocytes. J. Cell. Biochem. 106: 608-617 (2009). *
Carmel L, Efroni S, White PD, Aslakson E, Vollmer-Conna U, Rajeevan MS. Gene expression profile of empirically delineated classes of unexplained chronic fatigue. Pharmacogenomics 7: 375-386 (2006).
Carmody RJ, Ruan Q, Liou HC, Chen YH. Essential roles of c-Rel in TLR-induced IL-23 p19 gene expression in dendritic cells. J. Immunol. 178: 186-191 (2007). *
Carmona MC, Louche K, Lefebvre B, Pilon A, Hennuyer N, Audinot-Bouchez V, Fievet C, Torpier G, Formstecher P, Renard P, Lefebvre P, Dacquet C, Staels B, Casteilla L, Penicaud L. S 26948, a new specific PPARgamma modulator (SPPARM) with potent antidiabetic and antiatherogenic effects. Diabetes 56: 2797-2808 (2007). *
Carnahan VE, Redinbo MR. Structure and function of the human nuclear xenobiotic receptor PXR. Curr. Drug Metab. 6: 357-367 (2005).
Carney G, Wei S, Rizzo WB. Sjogren-Larsson syndrome: seven novel mutations in the fatty aldehyde dehydrogenase gene ALDH3A2. Hum. Mutat. 24: 186 (2004). *
Carobbio S, Frigerio F, Rubi B, Vetterli L, Bloksgaard M, Gjinovci A, Pournourmohammadi S, Herrera PL, Reith W, Mandrup S, Maechler P. Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis. J. Biol. Chem. 284: 921-929 (2009). *
Carol M, Borruel N, Antolin M, Llopis M, Casellas F, Guarner F, Malagelada JR. Modulation of apoptosis in intestinal lymphocytes by a probiotic bacteria in Crohn's disease. J. Leukoc. Biol. 79: 917-922 (2006). *
Carr DF, Alfirevic A, Tugwood JD, Barratt BJ, Sherwood J, Smith J, Pirmohamed M, Kevin Park B. Molecular and genetic association of interleukin-6 in tacrine-induced hepatotoxicity. Pharmacogenet. Genomics 17: 961-972 (2007).
Carr WH, Pando MJ, Parham P. KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand. J. Immunol. 175: 5222-5229 (2005). *
Carr WH, Rosen DB, Arase H, Nixon DF, Michaelsson J, Lanier LL. Cutting edge: KIR3DS1, a gene implicated in resistance to progression to AIDS, encodes a DAP12-associated receptor expressed on NK cells that triggers NK cell activation. J. Immunol. 178: 647-651 (2007). *
Carretero M, Escamez MJ, Garcia M, Duarte B, Holguin A, Retamosa L, Jorcano JL, Rio MD, Larcher F. In vitro and in vivo wound healing-promoting activities of human cathelicidin LL-37. J. Invest. Dermatol. 128: 223-236 (2008). *
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. II. TGF-beta-transgenic Th3 cells rescue IL-2-deficient mice from autoimmunity. J. Immunol. 178: 172-178 (2007). *
Carrier Y, Yuan J, Kuchroo VK, Weiner HL. Th3 cells in peripheral tolerance. I. Induction of Foxp3-positive regulatory T cells by Th3 cells derived from TGF-beta T cell-transgenic mice. J. Immunol. 178: 179-185 (2007). *
Carrillo-Lopez N, Alvarez-Hernandez D, Gonzalez-Suarez I, Roman-Garcia P, Valdivielso JM, Fernandez-Martin JL, Cannata-Andia JB. Simultaneous changes in the calcium-sensing receptor and the vitamin D receptor under the influence of calcium and calcitriol. Nephrol. Dial. Transplant. 23: 3479-3484 (2008).
Carrington M, Kissner T, Gerrard B, Ivanov S, O'Brien SJ, Dean M. Novel alleles of the chemokine-receptor gene CCR5. Am. J. Hum. Genet. 61: 1261-1267 (1997). *
Carrington M, Martin MP. The impact of variation at the KIR gene cluster on human disease. Curr. Top. Microbiol. Immunol. 298: 225-257 (2006).
Carroll JM, Crompton T, Seery JP, Watt FM. Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. J. Invest. Dermatol. 108: 412-422 (1997).
Carroll MC, Prodeus AP. Linkages of innate and adaptive immunity. Curr. Opin. Immunol. 10: 36-40 (1998).
Carta M, Stancampiano R, Tronci E, Collu M, Usiello A, Morelli M, Fadda F. Vitamin A deficiency induces motor impairments and striatal cholinergic dysfunction in rats. Neuroscience 139: 1163-1172 (2006). *
Carter BA, Prendergast DR, Taylor OA, Zimmerman TL, Furstenberg RV, Moore DD, Karpen SJ. Stigmasterol, a soy lipid-derived phytosterol, is an antagonist of the bile acid nuclear receptor FXR. Pediatr. Res. 62: 301-306 (2007). *
Carter CJ. Convergence of genes implicated in Alzheimer's disease on the cerebral cholesterol shuttle: APP, cholesterol, lipoproteins, and atherosclerosis. Neurochem. Int. 50: 12-38 (2007).
Carter MJ, Jones S, Camp NJ, Cox A, Mee J, Warren B, Duff GW, Lobo AJ, Di Giovine FS. Functional correlates of the interleukin-1 receptor antagonist gene polymorphism in the colonic mucosa in ulcerative colitis. Genes Immun. 5: 8-15 (2004). *
Cartier KC, Miscimarra L, Dazard JE, Song Y, Iyengar SK, Rao JS. Studying genetic determinants of natural variation in human gene expression using Bayesian ANOVA. BMC Proc. 1 Suppl. 1: S115 (2007). *
Carty M, Goodbody R, Schroder M, Stack J, Moynagh PN, Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat. Immunol. 7: 1074-1081 (2006). *
Carvajal K, Hernandez-Esquivel Mde L, Moreno-Sanchez R. PPARs, metabolic syndrome and cardiac diseases. Arch. Cardiol. Mex. 77 Suppl. 4: S4-S66-S76 (2007).
Carvalho B, Postma C, Mongera S, Hopmans E, Diskin S, van de Wiel MA, van Criekinge W, Thas O, Matthai A, Cuesta MA, Droste JS, Craanen ME, Schrock E, Ylstra B, Meijer GA. Multiple putative oncogenes at the chromosome 20q amplicon contribute to colorectal adenoma to carcinoma progression. Gut 58: 79-89 (2009).
Carvalho LS, Correa H, Silva GC, Campos FS, Baiao FR, Ribeiro LS, Faria AM, d'Avila Reis D. May genetic factors in fibromyalgia help to identify patients with differentially altered frequencies of immune cells? Clin. Exp. Immunol. 154: 346-352 (2008). *
Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP. Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate. Nat. Genet. 41: 619-624 (2009). *
Casas R, Lindau C, Zetterstrom O, Duchen K. Downregulation of CXCR6 and CXCR3 in lymphocytes from birch-allergic patients. Scand. J. Immunol. 68: 351-361 (2008). *
Casciola-Rosen L, Miagkov A, Nagaraju K, Askin F, Jacobson L, Rosen A, Drachman DB. Granzyme B: evidence for a role in the origin of myasthenia gravis. J. Neuroimmunol. 201-202: 33-40 (2008).
Casellas F, Antoln M, Varela E, Garca-Lafuente A, Guarner F, Borruel N, Armengol Miro JR, Malagelada JR. Fecal excretion of human deoxyribonucleic acid as an index of inflammatory activity in ulcerative colitis. Clin. Gastroenterol. Hepatol. 2: 683-689 (2004). *
Caserta TM, Knisley AA, Tan FK, Arnett FC, Brown TL. Genotypic analysis of the TGF beta-509 allele in patients with systemic lupus erythematosus and Sjogren's syndrome. Ann. Genet. 47: 359-363 (2004).
Casey WM, Brodie T, Yoon L, Ni H, Jordan HL, Cariello NF. Correlation analysis of gene expression and clinical chemistry to identify biomarkers of skeletal myopathy in mice treated with PPAR agonist GW610742X. Biomarkers 13: 364-376 (2008).
Cash HL, Whitham CV, Hooper LV. Refolding, purification, and characterization of human and murine RegIII proteins expressed in Escherichia coli. Protein Expr. Purif. 48: 151-159 (2006). *
Cassatella MA, da Silva GP, Tinazzi I, Facchetti F, Scapini P, Calzetti F, Tamassia N, Wei P, Nardelli B, Roschke V, Vecchi A, Mantovani A, Bambara LM, Edwards SW, Carletto A. Soluble TNF-like cytokine (TL1A) production by immune complexes stimulated monocytes in rheumatoid arthritis. J. Immunol. 178: 7325-7333 (2007). *
Cassiani-Ingoni R, Cabral ES, Lunemann JD, Garza Z, Magnus T, Gelderblom H, Munson PJ, Marques A, Martin R. Borrelia burgdorferi induces TLR1 and TLR2 in human microglia and peripheral blood monocytes but differentially regulates HLA-class II expression. J. Neuropathol. Exp. Neurol. 65: 540-548 (2006).
Castaldo G, Fuccio A, Salvatore D, Raia V, Santostasi T, Leonardi S, Lizzi N, La Rosa M, Rigillo N, Salvatore F. Liver expression in cystic fibrosis could be modulated by genetic factors different from the cystic fibrosis transmembrane regulator genotype. Am. J. Med. Genet. 98: 294-297 (2001). *
Castaldo G, Rippa E, Salvatore D, Sibillo R, Raia V, de Ritis G, Salvatore F. Severe liver impairment in a cystic fibrosis-affected child homozygous for the G542X mutation. Am. J. Med. Genet. 69: 155-158 (1997).
Castaneda FE, Walia B, Vijay-Kumar M, Patel NR, Roser S, Kolachala VL, Rojas M, Wang L, Oprea G, Garg P, Gewirtz AT, Roman J, Merlin D, Sitaraman SV. Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP. Gastroenterology 129: 1991-2008 (2005). *
Castellaneta A, Di Leo A, Francavilla R, Margiotta M, Barone M, Amoruso A, Troiani L, Thomson AW, Francavilla A. Functional modification of CD11c(+) liver dendritic cells during liver regeneration after partial hepatectomy in mice. Hepatology 43: 807-816 (2006). *
Castellanos-Rubio A, Martin-Pagola A, Santin I, Hualde I, Aransay AM, Castano L, Vitoria JC, Bilbao JR. Combined functional and positional gene information for the identification of susceptibility variants in celiac disease. Gastroenterology 134: 738-746 (2008). *
Castellanos-Rubio A, Santin I, Irastorza I, Castano L, Carlos Vitoria J, Ramon Bilbao J. TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin. Autoimmunity 42: 69-73 (2009).
Castellheim A, Brekke OL, Espevik T, Harboe M, Mollnes TE. Innate immune responses to danger signals in systemic inflammatory response syndrome and sepsis. Scand. J. Immunol. 69: 479-491 (2009). *
Castelli R, Ferrari B, Cortelezzi A, Guariglia A. Thromboembolic complications in malignant haematological disorders. Curr. Vasc. Pharmacol. Jan 1 [Epub ahead of print] (2009).
Castermans D, Vermeesch JR, Fryns JP, Steyaert JG, Van de Ven WJ, Creemers JW, Devriendt K. Identification and characterization of the TRIP8 and REEP3 genes on chromosome 10q21.3 as novel candidate genes for autism. Eur. J. Hum. Genet. 15: 422-431 (2007). *
Castiglione F, Taddei A, Degl'Innocenti DR, Buccoliero AM, Bechi P, Garbini F, Chiara FG, Moncini D, Cavallina G, Marascio L, Freschi G, Gian LT. Expression of estrogen receptor beta in colon cancer progression. Diagn. Mol. Pathol. 17: 231-236 (2008).
Castrillo A, Joseph SB, Marathe C, Mangelsdorf DJ, Tontonoz P. Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. J. Biol. Chem. 278: 10443-10449 (2003). *
Castriota G, Thompson GM, Lin Y, Scherer PE, Moller DE, Berger JP. Peroxisome proliferator-activated receptor gamma agonists inhibit adipocyte expression of alpha1-acid glycoprotein. Cell Biol. Int. 31: 586-591 (2007). *
Castro J, Amigo L, Miquel JF, Galman C, Crovari F, Raddatz A, Zanlungo S, Jalil R, Rudling M, Nervi F. Increased activity of hepatic microsomal triglyceride transfer protein and bile acid synthesis in gallstone disease. Hepatology 45: 1261-1266 (2007). *
Castro J, Balada E, Ordi-Ros J, Vilardell-Tarres M. The complex immunogenetic basis of systemic lupus erythematosus. Autoimmun. Rev. 7: 345-351 (2008).
Castro RE, Sola S, Ma X, Ramalho RM, Kren BT, Steer CJ, Rodrigues CM. A distinct microarray gene expression profile in primary rat hepatocytes incubated with ursodeoxycholic acid. J. Hepatol. 42: 897-906 (2005). *
Castro-Chavez F. Microarrays, antiobesity and the liver. Ann. Hepatol. 3: 137-145 (2004). *
Castro-Parodi M, Levi L, Dietrich V, Zotta E, Damiano AE. CFTR may modulate AQP9 functionality in preeclamptic placentas. Placenta May 27 [Epub ahead of print] (2009).
Catalano M, Cortelazzo A, Santi R, Contino L, Demicheli M, Yilmaz Y, Zorzetto M, Campo I, Lanati N, Emanuele E. The Pro12Ala polymorphism of peroxisome proliferator-activated receptor-gamma2 gene is associated with plasma levels of soluble RAGE (Receptor for Advanced Glycation Endproducts) and the presence of peripheral arterial disease. Clin. Biochem. 41: 981-985 (2008). *
Cataldegirmen G, Zeng S, Feirt N, Ippagunta N, Dun H, Qu W, Lu Y, Rong LL, Hofmann MA, Kislinger T, Pachydaki SI, Jenkins DG, Weinberg A, Lefkowitch J, Rogiers X, Yan SF, Schmidt AM, Emond JC. RAGE limits regeneration after massive liver injury by coordinated suppression of TNF-alpha and NF-kappaB. J. Exp. Med. 201: 473-484 (2005). *
Cataldo F, Lio D, Marino V, Scola L, Crivello A, Mule AM, Corazza GR; Groups of the SIGEP and "Club del Tenue". Cytokine genotyping (TNF and IL-10) in patients with celiac disease and selective IgA deficiency. Am. J. Gastroenterol. 98: 850-856 (2003). *
Caterino M, Ruoppolo M, Fulcoli G, Huynth T, Orru S, Baldini A, Salvatore F. Transcription factor TBX1 overexpression induces downregulation of proteins involved in retinoic acid metabolism: a comparative proteomic analysis. J. Proteome Res. Jan 29 [Epub ahead of print] (2009). *
Caudy AA, Reddy ST, Chatila T, Atkinson JP, Verbsky JW. CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome and defective IL-10 expression from CD4 lymphocytes. J. Allergy Clin. Immunol. 119: 482-487 (2007). *
Cauli A, Dessole G, Fiorillo MT, Vacca A, Mameli A, Bitti P, Passiu G, Sorrentino R, Mathieu A. Increased level of HLA-B27 expression in ankylosing spondylitis patients compared with healthy HLA-B27-positive subjects: a possible further susceptibility factor for the development of disease. Rheumatology (Oxford) 41: 1375-1379 (2002). *
Cavadini G, Petrzilka S, Kohler P, Jud C, Tobler I, Birchler T, Fontana A. TNF-alpha suppresses the expression of clock genes by interfering with E-box-mediated transcription. Proc. Natl. Acad. Sci. U.S.A. 104: 12843-12848 (2007). *
Cavadini P, Vermi W, Facchetti F, Fontana S, Nagafuchi S, Mazzolari E, Sediva A, Marrella V, Villa A, Fischer A, Notarangelo LD, Badolato R. AIRE deficiency in thymus of 2 patients with Omenn syndrome. J. Clin. Invest. 115: 728-732 (2005). *
Cavallaro S, Paratore S, Fradale F, de Vrij FM, Willemsen R, Oostra BA. Genes and pathways differentially expressed in the brains of Fxr2 knockout mice. Neurobiol. Dis. 32: 510-520 (2008).
Cave WT Jr. Dietary n-3 (omega-3) polyunsaturated fatty acid effects on animal tumorigenesis. FASEB J. 5: 2160-2166 (1991). *
Cavelier LB, Qiu Y, Bielicki JK, Afzal V, Cheng JF, Rubin EM. Regulation and activity of the human ABCA1 gene in transgenic mice. J. Biol. Chem. 276: 18046-18051 (2001). *
Cawkwell L, Sutherland F, Murgatroyd H, Jarvis P, Gray S, Cross D, Shepherd N, Day D, Quirke P. Defective hMSH2/hMLH1 protein expression is seen infrequently in ulcerative colitis associated colorectal cancers. Gut 46: 367-369 (2000). *
Cawood AL, Carroll MP, Wootton SA, Calder PC. Is there a case for n-3 fatty acid supplementation in cystic fibrosis? Curr. Opin. Clin. Nutr. Metab. Care 8: 153-159 (2005).
Cawthorn WP, Heyd F, Hegyi K, Sethi JK. Tumour necrosis factor-alpha inhibits adipogenesis via a beta-catenin/TCF4(TCF7L2)-dependent pathway. Cell Death Differ. 14: 1361-1373 (2007).
Cayla C, Schaak S, Crassous PA, Buffin-Meyer B, Delage C, Paris H, Senard JM, Denis C. Transcriptional down-regulation of human alpha(2A)-adrenoceptors by IFNgamma and TNFalpha in intestinal cells. Eur. J. Pharmacol. 588: 33-40 (2008).
Cayon A, Crespo J, Guerra AR, Pons-Romero F. Gene expression in obese patients with non-alcoholic steatohepatitis. Rev. Esp. Enferm. Dig. 100: 212-218 (2008).
Cebecauerova D, Jirasek T, Budisova L, Mandys V, Volf V, Novotna Z, Subhanova I, Hrebicek M, Elleder M, Jirsa M. Dual hereditary jaundice: simultaneous occurrence of mutations causing Gilbert's and Dubin-Johnson syndrome. Gastroenterology 129: 315-320 (2005). *
Cebotaru L, Vij N, Ciobanu I, Wright J, Flotte T, Guggino WB. Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and uF508 processing. J. Biol. Chem. 283: 21926-21933 (2008). *
Cecere A, Caiazzo R, Romano C, Gattoni A. Primary biliary cirrhosis. Clin. Ter. 149: 143-150 (1998).
Cecil DL, Johnson K, Rediske J, Lotz M, Schmidt AM, Terkeltaub R. Inflammation-induced chondrocyte hypertrophy is driven by receptor for advanced glycation end products. J. Immunol. 175: 8296-8302 (2005). *
Ceelie H, Spaargaren-Van Riel CC, De Jong M, Bertina RM, Vos HL. Functional characterization of transcription factor binding sites for HNF1-alpha, HNF3-beta (FOXA2), HNF4-alpha, Sp1 and Sp3 in the human prothrombin gene enhancer. J. Thromb. Haemost. 1: 1688-1698 (2003). *
Cejkova J, Ardan T, Jirsova K, Jechova G, Malec J, Simonova Z, Cejka C, Filipec M, Dotrelova D, Brunova B. The role of conjunctival epithelial cell xanthine oxidoreductase/xanthine oxidase in oxidative reactions on the ocular surface of dry eye patients with Sjogren's syndrome. Histol. Histopathol. 22: 997-1003 (2007).
Cejkova J, Ardan T, Simonova Z, Cejka C, Malec J, Dotrelova D, Brunova B. Decreased expression of antioxidant enzymes in the conjunctival epithelium of dry eye (Sjogren's syndrome) and its possible contribution to the development of ocular surface oxidative injuries. Histol. Histopathol. 23: 1477-1483 (2008). *
Celinska-Lowenhoff M, Undas A. Nonlipid effects of fibrates. Przegl. Lek. 61: 99-101 (2004).
Celius T, Garberg P, Lundgren B. Stable suppression of MDR1 gene expression and function by RNAi in Caco-2 cells. Biochem. Biophys. Res. Commun. 324: 365-371 (2004). *
Ceni E, Crabb DW, Foschi M, Mello T, Tarocchi M, Patussi V, Moraldi L, Moretti R, Milani S, Surrenti C, Galli A. Acetaldehyde inhibits PPARgamma via H(2)O(2)-mediated c-Abl activation in human hepatic stellate cells. Gastroenterology 131: 1235-1252 (2006). *
Centola M, Frank MB, Bolstad AI, Alex P, Szanto A, Zeher M, Hjelmervik TO, Jonsson R, Nakken B, Szegedi G, Szodoray P. Genome-scale assessment of molecular pathology in systemic autoimmune diseases using microarray technology: a potential breakthrough diagnostic and individualized therapy-design tool. Scand. J. Immunol. 64: 236-242 (2006). *
Centonze D, Muzio L, Rossi S, Cavasinni F, De Chiara V, Bergami A, Musella A, D'Amelio M, Cavallucci V, Martorana A, Bergamaschi A, Cencioni MT, Diamantini A, Butti E, Comi G, Bernardi G, Cecconi F, Battistini L, Furlan R, Martino G. Inflammation triggers synaptic alteration and degeneration in experimental autoimmune encephalomyelitis. J. Neurosci. 29: 3442-3452 (2009).
Centrella M, Christakos S, McCarthy TL. Skeletal hormones and the C/EBP and Runx transcription factors: interactions that integrate and redefine gene expression. Gene 342: 13-24 (2004). *
Ceperuelo-Mallafre V, Miranda M, Chacon MR, Vilarrasa N, Megia A, Gutierrez C, Fernandez-Real JM, Gomez JM, Caubet E, Fruhbeck G, Vendrell J. Adipose tissue expression of the glycerol channel aquaporin-7 gene is altered in severe obesity but not in type 2 diabetes. J. Clin. Endocrinol. Metab. 92: 3640-3645 (2007). *
Cepok S, Zhou D, Srivastava R, Nessler S, Stei S, Bussow K, Sommer N, Hemmer B. Identification of Epstein-Barr virus proteins as putative targets of the immune response in multiple sclerosis. J. Clin. Invest. 115: 1352-1360 (2005). *
Cereghini S. Liver-enriched transcription factors and hepatocyte differentiation. FASEB J. 10: 267-282 (1996). *
Cerman AA, Bozkurt S, Sav A, Tulunay A, Elbasi MO, Ergun T. Serum leptin levels, skin leptin and leptin receptor expression in psoriasis. Br. J. Dermatol. 159: 820-826 (2008). *
Cerruti F, Martano M, Petterino C, Bollo E, Morello E, Bruno R, Buracco P, Cascio P. Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer. Neoplasia 9: 960-969 (2007). *
Cerutti E, Campagnoli MF, Ferretti M, Garelli E, Crescenzio N, Rosolen A, Chiocchetti A, Lenardo MJ, Ramenghi U, Dianzani U. Co-inherited mutations of Fas and caspase-10 in development of the autoimmune lymphoproliferative syndrome. BMC Immunol. 8: 28 (2007). *
Cerveny L, Svecova L, Anzenbacherova E, Vrzal R, Staud F, Dvorak Z, Ulrichova J, Anzenbacher P, Pavek P. Valproic acid induces CYP3A4 and MDR1 genes expression by activation of constitutive androstane receptor and pregnane X receptor pathways. Drug Metab. Dispos. 35: 1032-1041 (2007). *
Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12: 721-727 (2000). *
Cesaratto L, Vascotto C, Calligaris S, Tell G. The importance of redox state in liver damage. Ann. Hepatol. 3: 86-92 (2004). *
Cetinkaya C, Hultquist A, Su Y, Wu S, Bahram F, P�hlman S, Guzhova I, Larsson LG. Combined IFN-gamma and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells. Mol. Cancer Ther. 6: 2634-2641 (2007).
Cha DR, Zhang X, Zhang Y, Wu J, Su DM, Han JY, Fang X, Yu B, Breyer MD, Guan Y. Peroxisome proliferator activated receptor alpha/gamma dual agonist tesaglitazar attenuates diabetic nephropathy in db/db mice. Diabetes 56: 2036-2045 (2007). *
Cha EJ, Oh BC, Wee HJ, Chi XZ, Goh YM, Lee KS, Ito Y, Bae SC. E1A physically interacts with RUNX3 and inhibits its transactivation activity. J. Cell. Biochem. 105: 236-244 (2008).
Cha JY, Kim H, Kim KS, Hur MW, Ahn Y. Identification of transacting factors responsible for the tissue-specific expression of human glucose transporter type 2 isoform gene. Cooperative role of hepatocyte nuclear factors 1alpha and 3beta. J. Biol. Chem. 275: 18358-18365 (2000). *
Cha JY, Repa JJ. The liver X receptor and hepatic lipogenesis: the carbohydrate-response element binding protein is a target gene of LXR. J. Biol. Chem. 282: 743-751 (2007). *
Cha S, Brayer J, Gao J, Brown V, Killedar S, Yasunari U, Peck AB. A dual role for interferon-gamma in the pathogenesis of Sjogren's syndrome-like autoimmune exocrinopathy in the nonobese diabetic mouse. Scand. J. Immunol. 60: 552-565 (2004). *
Cha Y, Sung MK, Jung KW, Kim HH, Lee SM, Park KS. Epigenetic deregulation of the human Oct4 promoter in mouse cells. Dev. Genes Evol. 218: 561-566 (2008). *
Chabane N, Zayed N, Afif H, Mfuna-Endam L, Benderdour M, Boileau C, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H. Histone deacetylase inhibitors suppress interleukin-1beta-induced nitric oxide and prostaglandin E(2) production in human chondrocytes. Osteoarthritis Cartilage 16: 1267-1274 (2008).
Chabas D. Osteopontin, a multi-faceted molecule. Med. Sci. (Paris) 21: 832-838 (2005).
Chabas D, Green AJ, Waubant E. Pediatric multiple sclerosis. NeuroRx. 3: 264-275 (2006).
Chadwick CC, Chippari S, Matelan E, Borges-Marcucci L, Eckert AM, Keith JC Jr, Albert LM, Leathurby Y, Harris HA, Bhat RA, Ashwell M, Trybulski E, Winneker RC, Adelman SJ, Steffan RJ, Harnish DC. Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity. Proc. Natl. Acad. Sci. U.S.A. 102: 2543-2548 (2005). *
Chae BS, Shin TY. Immunoregulatory abnormalities of T cells and hyperreactivity of B cells in the in vitro immune response in pristane-induced lupus mice. Arch. Pharm. Res. 30: 191-198 (2007).
Chae SC, Park BL, Park CS, Ryu HJ, Yang YS, Lee SO, Choi YH, Kim EM, Uh ST, Kim YH, Kim KK, Oh B, Chung HT, Kimm K, Shin HD. Putative association of RUNX1 polymorphisms with IgE levels in a Korean population. Exp. Mol. Med. 38: 583-588 (2006). *
Chakravarthy MV, Pan Z, Zhu Y, Tordjman K, Schneider JG, Coleman T, Turk J, Semenkovich CF. "New" hepatic fat activates PPARalpha to maintain glucose, lipid, and cholesterol homeostasis. Cell. Metab. 1: 309-322 (2005). *
Chakravarti N, Lotan R, Diwan AH, Warneke CL, Johnson MM, Prieto VG. Decreased expression of retinoid receptors in melanoma: entailment in tumorigenesis and prognosis. Clin. Cancer Res. 13: 4817-4824 (2007). *
Chakravarty SD, Zhu G, Tsai MC, Mohan VP, Marina S, Kirschner DE, Huang L, Flynn J, Chan J. Tumor necrosis factor blockade in chronic murine tuberculosis enhances granulomatous inflammation and disorganizes granulomas in the lungs. Infect. Immun. 76: 916-926 (2008). *
Chakraverty R, Flutter B, Fallah-Arani F, Eom HS, Means T, Andreola G, Schwarte S, Buchli J, Cotter P, Zhao G, Sykes M. The host environment regulates the function of CD8+ graft-versus-host-reactive effector cells. J. Immunol. 181: 6820-6828 (2008).
Chalasani N, Gorski JC, Asghar MS, Asghar A, Foresman B, Hall SD, Crabb DW. Hepatic cytochrome P450 2E1 activity in nondiabetic patients with nonalcoholic steatohepatitis. Hepatology 37: 544-550 (2003). *
Challet E. Clock genes, circadian rhythms and food intake. Pathol. Biol. (Paris) 55: 176-177 (2007).
Chaluvadi MR, Nyagode BA, Kinloch RD, Morgan ET. TLR4-dependent and -independent regulation of hepatic cytochrome P450 in mice with chemically induced inflammatory bowel disease. Biochem. Pharmacol. 77: 464-471 (2009). *
Chambon P. The retinoid signaling pathway: molecular and genetic analyses. Semin. Cell Biol. 5: 115-125 (1994).
Chambon P. A decade of molecular biology of retinoic acid receptors. FASEB J. 10: 940-954 (1996). *
Chambrier C, Bastard JP, Rieusset J, Chevillotte E, Bonnefont-Rousselot D, Therond P, Hainque B, Riou JP, Laville M, Vidal H. Eicosapentaenoic acid induces mRNA expression of peroxisome proliferator-activated receptor gamma. Obes. Res. 10: 518-525 (2002). *
Chamian F, Lowes MA, Lin SL, Lee E, Kikuchi T, Gilleaudeau P, Sullivan-Whalen M, Cardinale I, Khatcherian A, Novitskaya I, Wittkowski KM, Krueger JG. Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris. Proc. Natl. Acad. Sci. U.S.A. 102: 2075-2080 (2005). *
Chamorro CI, Weber G, Gronberg A, Pivarcsi A, Stahle M. The human antimicrobial peptide LL-37 suppresses apoptosis in keratinocytes. J. Invest. Dermatol. 129: 937-944 (2009). *
Chan AO, Rashid A. CpG island methylation in precursors of gastrointestinal malignancies. Curr. Mol. Med. 6: 401-408 (2006).
Chan BY, Gartland A, Wilson PJ, Buckley KA, Dillon JP, Fraser WD, Gallagher JA. PPAR agonists modulate human osteoclast formation and activity in vitro. Bone 40: 149-159 (2007). *
Chan J, Clements W, Field J, Nasa Z, Lock P, Yap F, Toh BH, Alderuccio F. Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice. J. Gene Med. 8: 1281-1290 (2006).
Chan JR, Blumenschein W, Murphy E, Diveu C, Wiekowski M, Abbondanzo S, Lucian L, Geissler R, Brodie S, Kimball AB, Gorman DM, Smith K, de Waal Malefyt R, Kastelein RA, McClanahan TK, Bowman EP. IL-23 stimulates epidermal hyperplasia via TNF and IL-20R2-dependent mechanisms with implications for psoriasis pathogenesis. J. Exp. Med. 203: 2577-2587 (2006). *
Chan LY, Leung JC, Tsang AW, Tang SC, Lai KN. Activation of tubular epithelial cells by mesangial-derived TNF-alpha: glomerulotubular communication in IgA nephropathy. Kidney Int. 67: 602-612 (2005). *
Chan MM, Chmura K, Chan ED. Increased NaCl-induced interleukin-8 production by human bronchial epithelial cells is enhanced by the DeltaF508/W1282X mutation of the cystic fibrosis transmembrane conductance regulator gene. Cytokine 33: 309-316 (2006).
Chan RW, Lai FM, Li EK, Tam LS, Chow KM, Lai KB, Li PK, Szeto CC. Intra-renal cytokine gene expression in lupus nephritis. Ann. Rheum. Dis. 66: 886-892 (2007). *
Chan SS, Schedlich LJ, Twigg SM, Baxter RC. Inhibition of adipocyte differentiation by insulin-like growth factor binding protein-3. Am. J. Physiol. Endocrinol. Metab. 296: E654-E663 (2009). *
Chan YC, Leung PS. Angiotensin II type 1 receptor-dependent nuclear factor-kappaB activation-mediated proinflammatory actions in a rat model of obstructive acute pancreatitis. J. Pharmacol. Exp. Ther. 323: 10-18 (2007). *
Chance SA. Subtle changes in the ageing human brain. Nutr. Health 18: 217-224 (2006).
Chanda D, Lee CH, Kim YH, Noh JR, Kim DK, Park JH, Hwang JH, Lee MR, Jeong KH, Lee IK, Kweon GR, Shong M, Oh GT, Chiang JY, Choi HS. Fenofibrate differentially regulates PAI-1 gene expression via AMPK-dependent induction of orphan nuclear receptor SHP. Hepatology [In Press] (2009).
Chandalia A, Clarke HJ, Clemens LE, Pandey B, Vicena V, Lee P, Lavan BE, Gregoire FM. MBX-102/JNJ39659100, a novel non-TZD selective partial PPAR-gamma agonist lowers triglyceride independently of PPAR-alpha activation. PPAR Res. 2009: 706852 (2009). *
Chandra AP, Ouyang L, Yi S, Wong JK, Ha H, Walters SN, Patel AT, Stokes R, Jardine M, Hawthorne WJ, O'Connell PJ. Chemokine and Toll-like receptor signaling in macrophage mediated islet xenograft rejection. Xenotransplantation 14: 48-59 (2007). *
Chandra P, Brouwer KL. The complexities of hepatic drug transport: current knowledge and emerging concepts. Pharm. Res. 21: 719-735 (2004). *
Chandra V, Huang P, Hamuro Y, Raghuram S, Wang Y, Burris TP, Rastinejad F. Structure of the intact PPAR-gamma-RXR-alpha nuclear receptor complex on DNA. Nature 456: 350-356 (2008). *
Chandrasekharan B, Bala V, Kolachala VL, Vijay-Kumar M, Jones D, Gewirtz AT, Sitaraman SV, Srinivasan S. Targeted deletion of neuropeptide Y (NPY) modulates experimental colitis. PLoS ONE 3: e3304 (2008). *
Chang AJ, Song DH, Wolfe MM. Attenuation of peroxisome proliferator activated receptor gamma (PPARgamma) mediates gastrin-stimulated colorectal cancer cell proliferation. J. Biol. Chem. 281: 14700-14710 (2006). *
Chang CC, Chen SC, Hsieh YH, Chen YC, Chen TY, Chu YH, Ma HJ, Chou MC, Tsai HT, Yang SF. Stromal cell-derived factor-1 but not its receptor, CXCR4, gene variants increase susceptibility and pathological development of hepatocellular carcinoma. Clin. Chem. Lab. Med. 47: 412-418 (2009).
Chang CC, Silvia EA, Ho EK, Vlad G, Suciu-Foca N, Vasilescu ER. Polymorphism and linkage disequilibrium of immunoglobulin-like transcript 3 gene. Hum. Immunol. 69: 284-290 (2008).
Chang CC, Wang SS, Huang HC, Lee FY, Lin HC, Lee JY, Chen YC, Lee SD. Chronic thalidomide administration enhances vascular responsiveness to vasopressin in portal-systemic collaterals of bile duct-ligated rats. J. Chin. Med. Assoc. 72: 234-242 (2009).
Chang CH, Flavell RA. Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J. Exp. Med. 181: 765-767 (1995). *
Chang CL, Hong E, Lao-Sirieix P, Fitzgerald RC. A novel role for the retinoic acid-catabolizing enzyme CYP26A1 in Barrett's associated adenocarcinoma. Oncogene 27: 2951-260 (2008). *
Chang H, Hanawa H, Liu H, Yoshida T, Hayashi M, Watanabe R, Abe S, Toba K, Yoshida K, Elnaggar R, Minagawa S, Okura Y, Kato K, Kodama M, Maruyama H, Miyazaki J, Aizawa Y. Hydrodynamic-based delivery of an interleukin-22-Ig fusion gene ameliorates experimental autoimmune myocarditis in rats. J. Immunol. 177: 3635-3643 (2006). *
Chang H, Hanawa H, Yoshida T, Hayashi M, Liu H, Ding L, Otaki K, Hao K, Yoshida K, Kato K, Toba K, Kodama M, Maruyama H, Miyazaki J, Aizawa Y. Alteration of IL-17 related protein expressions in experimental autoimmune myocarditis and inhibition of IL-17 by IL-10-Ig fusion gene transfer. Circ. J. 72: 813-819 (2008). *
Chang HD, Radbruch A. The pro- and anti-inflammatory potential of interleukin-12. Ann. N. Y. Acad. Sci. 1109: 40-46 (2007). *
Chang HS, Kim JS, Lee JH, Cho JI, Rhim TY, Uh ST, Park BL, Chung IY, Park CS, Shin HD. A single nucleotide polymorphism on the promoter of eotaxin1 associates with its mRNA expression and asthma phenotypes. J. Immunol. 174: 1525-1531 (2005). *
Chang JH, Lin KH, Shih CH, Chang YJ, Chi HC, Chen SL. Myogenic basic helix-loop-helix proteins regulate the expression of peroxisomal proliferator activated receptor-gamma coactivator-1alpha. Endocrinology 147: 3093-3106 (2006). *
Chang JH, McCluskey PJ, Wakefield D. Toll-like receptors in ocular immunity and the immunopathogenesis of inflammatory eye disease. Br. J. Ophthalmol. 90: 103-108 (2006).
Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins S, Wang W, Wang Y, Lacava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S. Liver X receptor is a therapeutic target for photoaging and chronological skin aging. Mol. Endocrinol. 22: 2407-2419 (2008). *
Chang LT, Sun CK, Wang CY, Youssef AA, Wu CJ, Chua S, Yip HK. Downregulation of peroxisme proliferator activated receptor gamma co-activator 1alpha in diabetic rats. Int. Heart J. 47: 901-910 (2006).
Chang MH, Dipiero J, Sonnichsen FD, Romero MF. Entry to "HCO3 tunnel" revealed by SLC4A4 human mutation and structural model. J. Biol. Chem. 283: 18402-18410 (2008). *
Chang Q, Zhang Y, Beezhold KJ, Bhatia D, Zhao H, Chen J, Castranova V, Shi X, Chen F. Sustained JNK1 activation is associated with altered histone H3 methylations in human liver cancer. J. Hepatol. 50: 323-333 (2009).
Chang TK, Bandiera SM, Chen J. Constitutive androstane receptor and pregnane X receptor gene expression in human liver: interindividual variability and correlation with CYP2B6 mRNA levels. Drug Metab. Dispos. 31: 7-10 (2003). *
Chang TT, Hughes-Fulford M. Monolayer and spheroid culture of human liver hepatocellular carcinoma cell line cells demonstrate distinct global gene expression patterns and functional phenotypes. Tissue Eng. Part A. 15: 559-567 (2009).
Chang WW, Su IJ, Lai MD, Chang WT, Huang W, Lei HY. Toll-like receptor 4 plays an anti-HBV role in a murine model of acute hepatitis B virus expression. World J. Gastroenterol. 11: 6631-6637 (2005). *
Chang X, Gao JX, Jiang Q, Wen J, Seifers N, Su L, Godfrey VL, Zuo T, Zheng P, Liu Y. The Scurfy mutation of FoxP3 in the thymus stroma leads to defective thymopoiesis. J. Exp. Med. 202: 1141-1151 (2005). *
Chang X, Yamada R, Sawada T, Suzuki A, Kochi Y, Yamamoto K. The inhibition of antithrombin by peptidylarginine deiminase 4 may contribute to pathogenesis of rheumatoid arthritis. Rheumatology (Oxford) 44: 293-298 (2005). *
Chang X, Yamada R, Suzuki A, Kochi Y, Sawada T, Yamamoto K. Citrullination of fibronectin in rheumatoid arthritis synovial tissue. Rheumatology (Oxford) 44: 1374-1382 (2005). *
Chang X, Yamada R, Suzuki A, Sawada T, Yoshino S, Tokuhiro S, Yamamoto K. Localization of peptidylarginine deiminase 4 (PADI4) and citrullinated protein in synovial tissue of rheumatoid arthritis. Rheumatology (Oxford) 44: 40-50 (2005). *
Chang X, Zheng P, Liu Y. Homeostatic proliferation in the mice with germline FoxP3 mutation and its contribution to fatal autoimmunity. J. Immunol. 181: 2399-2406 (2008).
Chang XH, Zhang L, Yang R, Feng J, Cheng YX, Cheng HY, Ye X, Fu TY, Cui H. Screening for genes associated with ovarian cancer prognosis. Chin. Med. J. (Engl.) 122: 1167-1172 (2009).
Chang Y, Yap S, Ge X, Piganelli J, Bertera S, Giannokakis N, Mathews C, Prud'homme G, Trucco M. DNA vaccination with an insulin construct and a chimeric protein binding to both CTLA4 and CD40 ameliorates type 1 diabetes in NOD mice. Gene Ther. 12: 1679-1685 (2005). *
Chang YC, Chen TC, Lee CT, Yang CY, Wang HW, Wang CC, Hsieh SL. Epigenetic control of MHC-II expression in tumor-associated macrophages by decoy receptor 3. Blood 111: 5054-5063 (2008). *
Chang YC, Kao YH, Hu DN, Tsai LY, Wu WC. All-trans retinoic acid remodels extracellular matrix and suppresses laminin-enhanced contractility of cultured human retinal pigment epithelial cells. Exp. Eye Res. 88: 900-909 (2009).
Chang YT, Hsu C, Jeng YM, Chang MC, Wei SC, Wong JM. Expression of the caudal-type homeodomain transcription factor CDX2 is related to clinical outcome in biliary tract carcinoma. J. Gastroenterol. Hepatol. 22: 389-394 (2007). *
Chanson M, Berclaz PY, Scerri I, Dudez T, Wernke-Dollries K, Pizurki L, Pavirani A, Fiedler MA, Suter S. Regulation of gap junctional communication by a pro-inflammatory cytokine in cystic fibrosis transmembrane conductance regulator-expressing but not cystic fibrosis airway cells. Am. J. Pathol. 158: 1775-1784 (2001). *
Chanson M, Scerri I, Suter S. Defective regulation of gap junctional coupling in cystic fibrosis pancreatic duct cells. J. Clin. Invest. 103: 1677-1684 (1999). *
Chao C, Youssef J, Rezaiekhaleigh M, Birnbaum LS, Badr M. Senescence-associated decline in hepatic peroxisomal enzyme activities corresponds with diminished levels of retinoid X receptor alpha, but not peroxisome proliferator-activated receptor alpha. Mech. Ageing Dev. 123: 1469-1476 (2002).
Chao EY, Caravella JA, Watson MA, Campobasso N, Ghisletti S, Billin AN, Galardi C, Wang P, Laffitte BA, Iannone MA, Goodwin BJ, Nichols JA, Parks DJ, Stewart E, Wiethe RW, Williams SP, Smallwood A, Pearce KH, Glass CK, Willson TM, Zuercher WJ, Collins JL. Structure-guided design of N-phenyl tertiary amines as transrepression-selective liver X receptor modulators with anti-inflammatory activity. J. Med. Chem. 51: 5758-5765 (2008). *
Chao YC, Chang SF, Lu SC, Hwang TC, Hsieh WH, Liaw J. Ethanol enhanced in vivo gene delivery with non-ionic polymeric micelles inhalation. J. Control. Release 118: 105-117 (2007).
Chaparro M, Sanz-Cameno P, Trapero-Marugan M, Garcia-Buey L, Moreno-Otero R. Mechanisms of angiogenesis in chronic inflammatory liver disease. Ann. Hepatol. 6: 208-213 (2007). *
Chapkin RS, Seo J, McMurray DN, Lupton JR. Mechanisms by which docosahexaenoic acid and related fatty acids reduce colon cancer risk and inflammatory disorders of the intestine. Chem. Phys. Lipids 153: 14-23 (2008). *
Chapman C, Morgan LM, Murphy MC. Maternal and early dietary fatty acid intake: changes in lipid metabolism and liver enzymes in adult rats. J. Nutr. 130: 146-151 (2000). *
Chapman RW. The management of primary sclerosing cholangitis. Curr. Gastroenterol. Rep. 5: 9-17 (2003).
Chapman RW, Kelly PM, Heryet A, Jewell DP, Fleming KA. Expression of HLA-DR antigens on bile duct epithelium in primary sclerosing cholangitis. Gut 29: 422-427 (1988). *
Chapuis J, Hot D, Hansmannel F, Kerdraon O, Ferreira S, Hubans C, Maurage CA, Huot L, Bensemain F, Laumet G, Ayral AM, Fievet N, Hauw JJ, Dekosky ST, Lemoine Y, Iwatsubo T, Wavrant-Devrieze F, Dartigues JF, Tzourio C, Buee L, Pasquier F, Berr C, et al. Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease. Mol. Psychiatry Feb 10 [Epub ahead of print] (2009).
Charoensit P, Kawakami S, Higuchi Y, Hashida M. Incorporation of all-trans retinoic acid into lipoplexes inhibits nuclear factor kappaB activation mediated liver injury induced by lipoplexes in mice. J. Gene Med. 10: 61-69 (2008). *
Charrier-Hisamuddin L, Laboisse CL, Merlin D. ADAM-15: a metalloprotease that mediates inflammation. FASEB J. 22: 641-653 (2008). *
Charron DJ. New aspects of HLA: perspectives for rheumatoid arthritis. Clin. Exp. Rheumatol. 10: 293-296 (1992).
Chase MA, Wheeler DS, Lierl KM, Hughes VS, Wong HR, Page K. Hsp72 induces inflammation and regulates cytokine production in airway epithelium through a TLR4- and NF-kappaB-dependent mechanism. J. Immunol. 179: 6318-6324 (2007). *
Chatellard P, Pankiewicz R, Meier E, Durrer L, Sauvage C, Imhof MO. The IE2 promoter/enhancer region from mouse CMV provides high levels of therapeutic protein expression in mammalian cells. Biotechnol. Bioeng. 96: 106-117 (2007). *
Chatterjee R, Batra J, Kumar A, Mabalirajan U, Nahid S, Niphadkar PV, Ghosh B. Interleukin-10 promoter polymorphisms and atopic asthma in North Indians. Clin. Exp. Allergy 35: 914-919 (2005).
Chaturvedi RK, Adhihetty P, Shukla S, Hennessy T, Calingasan N, Yang L, Starkov A, Kiaei M, Cannella M, Sassone J, Ciammola A, Squitieri F, Beal MF. Impaired PGC-1alpha function in muscle in Huntington's disease. Hum. Mol. Genet. May 21 [Epub ahead of print] (2009).
Chaturvedi RK, Flint Beal M. PPAR: a therapeutic target in Parkinson's disease. J. Neurochem. 106: 506-518 (2008). *
Chatzantoni K, Mouzaki A. Anti-TNF-alpha antibody therapies in autoimmune diseases. Curr. Top. Med. Chem. 6: 1707-1714 (2006).
Chatzikyriakidou A, Georgiou I, Voulgari PV, Papadopoulos CG, Tzavaras T, Drosos AA. Transcription regulatory polymorphism -43T>C in the 5'-flanking region of SLC19A1 gene could affect rheumatoid arthritis patient response to methotrexate therapy. Rheumatol. Int. 27: 1057-1061 (2007). *
Chatzipantelis P, Lazaris AC, Kafiri G, Nonni A, Papadimitriou K, Xiromeritis K, Patsouris ES. CD56 as a useful marker in the regenerative process of the histological progression of primary biliary cirrhosis. Eur. J. Gastroenterol. Hepatol. 20: 837-842 (2008).
Chatzipantelis P, Lazaris AC, Kafiri G, Papadimitriou K, Papathomas TG, Nonni A, Patsouris ES. Cytokeratin-7, cytokeratin-19, and c-Kit: immunoreaction during the evolution stages of primary biliary cirrhosis. Hepatol. Res. 36: 182-187 (2006).
Chaudhuri V, Tayal R, Nayak B, Acharya SK, Panda SK. Occult hepatitis B virus infection in chronic liver disease: full-length genome and analysis of mutant surface promoter. Gastroenterology 127: 1356-1371 (2004). *
Chaudiere J, Ferrari-Iliou R. Intracellular antioxidants: from chemical to biochemical mechanisms. Food Chem. Toxicol. 37: 949-962 (1999).
Chaung WW, Jacob A, Ji Y, Wang P. Suppression of PGC-1alpha by ethanol: implications of its role in alcohol induced liver injury. Int. J. Clin. Exp. Med. 1: 161-170 (2008).
Chava KR, Karpurapu M, Wang D, Bhanoori M, Kundumani-Sridharan V, Zhang Q, Ichiki T, Glasgow WC, Rao GN. CREB-mediated IL-6 expression is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration. Arterioscler. Thromb. Vasc. Biol. 29: 809-815 (2009).
Chavanas S, Mechin MC, Takahara H, Kawada A, Nachat R, Serre G, Simon M. Comparative analysis of the mouse and human peptidylarginine deiminase gene clusters reveals highly conserved non-coding segments and a new human gene, PADI6. Gene 330: 19-27 (2004). *
Chawla A, Repa JJ, Evans RM, Mangelsdorf DJ. Nuclear receptors and lipid physiology: opening the X-files. Science 294: 1866-1870 (2001). *
Chazouilleres O. Primary sclerosing cholangitis and biliary malignancy: a glimmer of hope? J. Hepatol. 40: 857-859 (2004). *
Chearwae W, Bright JJ. PPARgamma agonists inhibit growth and expansion of CD133+ brain tumour stem cells. Br. J. Cancer 99: 2044-2053 (2008). *
Chearwae W, Bright JJ. 15-Deoxy-delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of Toll-like receptors 4 and 9 in autoimmune T lymphocyte. J. Clin. Immunol. 28: 558-570 (2008). *
Chedid A, Mendenhall CL, Moritz TE. The antigenic heterogeneity of the bile duct epithelium in alcoholic liver disease. VA Cooperative Study Group 275. Arch. Pathol. Lab. Med. 123: 411-414 (1999). *
Cheema SK, Agarwal-Mawal A, Murray CM, Tucker S. Lack of stimulation of cholesterol ester transfer protein by cholesterol in the presence of a diet high in monounsaturated fatty acids. J. Lipid Res. 46: 2356-2366 (2005). *
Cheepala SB, Yin W, Syed Z, Gill JN, McMillian A, Kleiner HE, Lynch M, Loganantharaj R, Trutschl M, Cvek U, Clifford JL. Identification of the B-Raf/Mek/Erk MAP kinase pathway as a target for all-trans retinoic acid during skin cancer promotion. Mol. Cancer 8: 27 (2009). *
Chelvarajan RL, Liu Y, Popa D, Getchell ML, Getchell TV, Stromberg AJ, Bondada S. Molecular basis of age-associated cytokine dysregulation in LPS-stimulated macrophages. J. Leukoc. Biol. 79: 1314-1327 (2006). *
Chen A, Zheng S. Curcumin inhibits connective tissue growth factor gene expression in activated hepatic stellate cells in vitro by blocking NF-kappaB and ERK signalling. Br. J. Pharmacol. 153: 557-567 (2008). *
Chen AB, Hamamura K, Wang G, Xing W, Mohan S, Yokota H, Liu Y. Model-based comparative prediction of transcription-factor binding motifs in anabolic responses in bone. Genomics Proteomics Bioinformatics 5: 158-165 (2007).
Chen B, Fang J, Zhang W, Jin Z, Yu Z, Cai W. Detection of C1236T, G2677T/A, and C3435T polymorphism of MDR1 by amplification refractory mutation system PCR. J. Clin. Lab. Anal. 23: 110-116 (2009).
Chen B, Zhang Y, Liu G, Guan GJ, Hou XH, Li XG, Liu JL. Effects of valsartan, mycophenolate mofetil and their combined application on TRAIL and nuclear factor-kappaB expression in the kidneys of diabetic rats. Zhonghua Yi Xue Za Zhi 88: 540-545 (2008).
Chen BC, Kuo KK, Chen YH, Liu CH, Tsai LY, Hsu HK, Hsu C. Retinoid X receptor alpha participation in dexamethasone induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver. Shock Nov 11 [Epub ahead of print] (2008).
Chen C, Bazan NG. Lipid signaling: sleep, synaptic plasticity, and neuroprotection. Prostaglandins