• Abbas G, Lindor KD. Cholangiocarcinoma in primary sclerosing cholangitis. J. Gastrointest. Cancer 40: 19-25 (2009). *

• Abbas S, Brauch H, Chang-Claude J, Dunnebier T, Flesch-Janys D, Hamann U, Hein R, Justenhoven C, Salazar R. Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy. Int. J. Cancer Sep 8 [Epub ahead of print] (2009). *

• Abdul-Baki H, Elhajj I, El-Zahabi LM, Azar C, Aoun E, Zantout H, Nasreddine W, Ayyach B, Mourad FH, Soweid A, Barada KA, Sharara AI. Clinical epidemiology of inflammatory bowel disease in Lebanon. Inflamm. Bowel Dis. 13: 475-480 (2007). *

• Abdullah MA. Epidemiology of type I diabetes mellitus among Arab children. Saudi Med. J. 26: 911-917 (2005).

• Aberra FN, Stettler N, Brensinger C, Lichtenstein GR, Lewis JD. Risk for active tuberculosis in inflammatory bowel disease patients. Clin. Gastroenterol. Hepatol. 5: 1070-1075 (2007).

• Abramov VM, Khlebnikov VS, Vasiliev AM, Kosarev IV, Vasilenko RN, Kulikova NL, Khodyakova AV, Evstigneev VI, Uversky VN, Motin VL, Smirnov GB, Brubaker RR. Attachment of LcrV from Yersinia pestis at dual binding sites to human TLR-2 and human IFN-gamma receptor. J. Proteome Res. 6: 2222-2231 (2007). *

• Accomando S, Cataldo F. The global village of celiac disease. Dig. Liver Dis. 36: 492-498 (2004).

• Acheson DW. Foodborne infections. Curr. Opin. Gastroenterol. 15: 538 (1999).

• Adamopoulos AB. Inflammatory bowel disease (IBD) and the liver. Annals of Gastroenterology 19: 146-151 (2006). *

• Adams LA, Harmsen S, St Sauver JL, Charatcharoenwitthaya P, Enders FB, Therneau T, Angulo P. Nonalcoholic fatty liver disease increases risk of death among patients with diabetes: a community-based cohort study. Am. J. Gastroenterol. Feb 9 [Epub ahead of print] (2010). *

• Adams LA, Lymp JF, St Sauver J, Sanderson SO, Lindor KD, Feldstein A, Angulo P. The natural history of nonalcoholic fatty liver disease: a population-based cohort study. Gastroenterology 129: 113-121 (2005). *

• Adler AI, Shine BS, Chamnan P, Haworth CS, Bilton D. Genetic determinants and epidemiology of cystic fibrosis-related diabetes - results from a British cohort of children and adults. Diabetes Care 31: 1789-1794 (2008). *

• Agarwal SK, Gourh P, Shete S, Paz G, Divecha D, Reveille JD, Assassi S, Tan FK, Mayes MD, Arnett FC. Association of interleukin 23 receptor polymorphisms with anti-topoisomerase-I positivity and pulmonary hypertension in systemic sclerosis. J. Rheumatol. 36: 2715-2723 (2009).

• Ahmad Y, Shelmerdine J, Bodill H, Lunt M, Pattrick MG, Teh LS, Bernstein RM, Walker MG, Bruce IN. Subclinical atherosclerosis in systemic lupus erythematosus (SLE): the relative contribution of classic risk factors and the lupus phenotype. Rheumatology (Oxford) 46: 983-988 (2007). *

• Ahmad YA, Bruce IN. Genetic epidemiology: systemic lupus erythematosus. Arthritis Res. 3: 331-336 (2001). *

• Ahmadi KR, Hall MA, Norman P, Vaughan RW, Snieder H, Spector TD, Lanchbury JS. Genetic determinism in the relationship between human CD4+ and CD8+ T lymphocyte populations? Genes Immun. 2: 381-387 (2001). *

• Ahmadi KR, Lanchbury JS, Reed P, Chiano M, Thompson D, Galley M, Line A, Lank E, Wong HJ, Strachan D, Spector TD. Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels. Genes Immun. 4: 289-297 (2003). *

• Ahn J, Albanes D, Berndt SI, Peters U, Chatterjee N, Freedman ND, Abnet CC, Huang WY, Kibel AS, Crawford ED, Weinstein SJ, Chanock SJ, Schatzkin A, Hayes RB; for the Prostate, Lung, Colorectal, and Ovarian (PLCO) Trial Project Team. Vitamin D-related genes, serum vitamin D concentrations, and prostate cancer risk. Carcinogenesis 30: 769-776 (2009). *

• Ahn J, Gammon MD, Santella RM, Gaudet MM, Britton JA, Teitelbaum SL, Terry MB, Neugut AI, Eng SM, Zhang Y, Garza C, Ambrosone CB. Effects of glutathione S-transferase A1 (GSTA1) genotype and potential modifiers on breast cancer risk. Carcinogenesis 27: 1876-1882 (2006). *

• Ahrens W, Timmer A, Vyberg M, Fletcher T, Guenel P, Merler E, Merletti F, Morales M, Olsson H, Olsen J, Hardell L, Kaerlev L, Raverdy N, Lynge E. Risk factors for extrahepatic biliary tract carcinoma in men: medical conditions and lifestyle: results from a European multicentre case-control study. Eur. J. Gastroenterol. Hepatol. 19: 623-630 (2007).

• Aissani B, Ogwaro KM, Shrestha S, Tang J, Breen EC, Wong HL, Jacobson LP, Rabkin CS, Ambinder RF, Martinez-Maza O, Kaslow RA. The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma. J. Acquir. Immune Defic. Syndr. Aug 3 [Epub ahead of print] (2009).

• Akedo I, Ishikawa H, Nakamura T, Kimura K, Takeyama I, Suzuki T, Kameyama M, Sato S, Nakamura T, Matsuzawa Y, Kakizoe T, Otani T. Three cases with familial adenomatous polyposis diagnosed as having malignant lesions in the course of a long-term trial using docosahexanoic acid (DHA)-concentrated fish oil capsules. Jpn. J. Clin. Oncol. 28: 762-765 (1998).

• Al Olama AA, Kote-Jarai Z, Giles GG, Guy M, Morrison J, Severi G, Leongamornlert DA, Tymrakiewicz M, Jhavar S, Saunders E, Hopper JL, Southey MC, Muir KR, English DR, Dearnaley DP, Ardern-Jones AT, et al. Multiple loci on 8q24 associated with prostate cancer susceptibility. Nat. Genet. 41: 1058-1060 (2009). *

• al Sharif F, Ollier WE, Hajeer AH. A rare polymorphism at position -28 in the human RANTES promoter. Eur. J. Immunogenet. 26: 373-374 (1999). *

• Al-Ansari AS, Ollier WE, Villarreal J, Ordi J, Teh LS, Hajeer AH. Tumor necrosis factor receptor II (TNFRII) exon 6 polymorphism in systemic lupus erythematosus. Tissue Antigens 55: 97-99 (2000). *

• Al-Araji A, Kidd DP. Neuro-Behcet's disease: epidemiology, clinical characteristics, and management. Lancet Neurol. 8: 192-204 (2009).

• Al-Ghamdi AS, Al-Mofleh IA, Al-Rashed RS, Al-Amri SM, Aljebreen AM, Isnani AC, El-Badawi R. Epidemiology and outcome of Crohn's disease in a teaching hospital in Riyadh. World J. Gastroenterol. 10: 1341-1344 (2004). *

• Al-Kateb H, Mirea L, Xie X, Sun L, Liu M, Chen H, Bull SB, Boright AP, Paterson AD. Multiple variants in vascular endothelial growth factor (VEGF) are risk factors for time to severe retinopathy in type 1 diabetes: the DCCT/EDIC genetics study. Diabetes 56: 2161-2168 (2007). *

• Al-Mofarreh MA, Al Mofleh IA, Al-Teimi IN, Al-Jebreen AM. Crohn's disease in a Saudi outpatient population: is it still rare? Saudi J. Gastroenterol. 15: 111-116 (2009). *

• Al-Mukhaizeem KA, Rosenberg A, Sherker AH. Nodular regenerative hyperplasia of the liver: an under-recognized cause of portal hypertension in hematological disorders. Am. J. Hematol. 75: 225-230 (2004). *

• Aladesanmi OA. Sarcoidosis: an update for the primary care physician. MedGenMed. 6: 7 (2004). *

• Alamanos Y, Papadopoulos NG, Voulgari PV, Karakatsanis A, Siozos C, Drosos AA. Epidemiology of ankylosing spondylitis in Northwest Greece, 1983-2002. Rheumatology (Oxford) 43: 615-618 (2004). *

• Alamanos Y, Tsifetaki N, Voulgari PV, Venetsanopoulou AI, Siozos C, Drosos AA. Epidemiology of primary Sjogren's syndrome in north-west Greece, 1982-2003. Rheumatology (Oxford) 45: 187-191 (2006). *

• Alamanos Y, Voulgari PV, Drosos AA. Incidence and prevalence of psoriatic arthritis: a systematic review. J. Rheumatol. 35: 1354-1358 (2008). *

• Alamanos Y, Voulgari PV, Drosos AA. Incidence and prevalence of rheumatoid arthritis, based on the 1987 American College of Rheumatology criteria: a systematic review. Semin. Arthritis Rheum. 36: 182-188 (2006). *

• Alansari A, Gul A, Inanc M, Ordi J, Teh LS, Ollier WE, Gonzalez-Gay MA, Hajeer AH. Fc receptor gamma subunit polymorphisms and systemic lupus erythematosus. Saudi Med. J. 25: 1445-1448 (2004).

• Alansari A, Hajeer A, Teh LS, Bayat A, Mysercough A, Gul A, Inanc M, Ordi-Ros J, Ollier W. Transforming growth factor-12 polymorphism and systemic lupus erythematosus. J. Rheumatol. 29: 1189-1191 (2002).

• Alansari A, Hajeer AH, Bayat A, Eyre S, Carthy D, Ollier WE. Two novel polymorphisms in the human transforming growth factor beta 2 gene. Genes Immun. 2: 295-296 (2001). *

• Albala C, Villarroel A, Santos JL, Angel B, Lera L, Liberman C, Sanchez H, Perez-Bravo F. FABP2 Ala54Thr polymorphism and diabetes in Chilean elders. Diabetes Res. Clin. Pract. 77: 245-250 (2007).

• Albanese E, Dangour AD, Uauy R, Acosta D, Guerra M, Guerra SS, Huang Y, Jacob K, Llibre de Rodriguez J, Noriega LH, Salas A, Sosa AL, Sousa RM, Williams J, Ferri CP, Prince MJ. Dietary fish and meat intake and dementia in Latin America, China, and India: a 10/66 Dementia Research Group population-based study. Am. J. Clin. Nutr. 90: 392-400 (2009). *

• Albermann N, Schmitz-Winnenthal FH, Z'graggen K, Volk C, Hoffmann MM, Haefeli WE, Weiss J. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver. Biochem. Pharmacol. 70: 949-958 (2005). *

• Alef K. Clostridium difficile-associated disease. Implications for midwifery practice. J. Nurse Midwifery 44: 19-29 (1999).

• Ali S, Tamboli CP. Advances in epidemiology and diagnosis of inflammatory bowel diseases. Curr. Gastroenterol. Rep. 10: 576-584 (2008).

• Alic M. Crohn's disease epidemiology at the turn of the century-solving the puzzle. Am. J. Gastroenterol. 95: 321-323 (2000). *

• Alic M. Epidemiology supports oral contraceptives as a risk factor in Crohn's disease. Gut 46: 140 (2000). *

• Alizadeh BZ, Njajou OT, Houwing-Duistermaat JJ, Jong Gd G, Vergeer JM, Hofman A, Pols HA, Duijn CM. Does bilirubin protect against hemochromatosis gene (HFE) related mortality? Am. J. Med. Genet. 129A: 39-43 (2004). *

• Alkhateeb A, Fain PR, Thody A, Bennett DC, Spritz RA. Epidemiology of vitiligo and associated autoimmune diseases in Caucasian probands and their families. Pigment Cell Res. 16: 208-214 (2003). *

• Almadi MA, Ghosh S, Aljebreen AM. Differentiating intestinal tuberculosis from Crohn's disease: a diagnostic challenge. Am. J. Gastroenterol. 104: 1003-1012 (2009). *

• Almeda-Valdes P, Cuevas-Ramos D, Aguilar-Salinas CA. Metabolic syndrome and non-alcoholic fatty liver disease. Ann. Hepatol. 8 Suppl. 1: S18-S24 (2009). *

• Almendingen K, Hostmark AT, Fausa O, Mosdol A, Aabakken L, Vatn MH. Familial adenomatous polyposis patients have high levels of arachidonic acid and docosahexaenoic acid and low levels of linoleic acid and alpha-linolenic acid in serum phospholipids. Int. J. Cancer 120: 632-637 (2007). *

• Alonso A, Egues Olazabal N, Ayo Martin O. Infection by Epstein-Barr virus and multiple sclerosis. Neurologia 21: 249-255 (2006).

• Alonso A, Hernan MA. Temporal trends in the incidence of multiple sclerosis: a systematic review. Neurology 71: 129-135 (2008).

• Alonso A, Hernan MA, Ascherio A. Allergy, family history of autoimmune diseases, and the risk of multiple sclerosis. Acta Neurol. Scand. 117: 15-20 (2008). *

• Alonso A, Jick SS, Hernan MA. Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis. Neurology 66: 572-575 (2006).

• Alonso A, Jick SS, Jick H, Hernan MA. Antibiotic use and risk of multiple sclerosis. Am. J. Epidemiol. 163: 997-1002 (2006). *

• Alonso A, Jick SS, Olek MJ, Hernán MA. Incidence of multiple sclerosis in the United Kingdom: findings from a population-based cohort. J. Neurol. 254: 1736-1741 (2007).

• Alqahtani S, Coffin CS, Burak K, Chen F, Macgregor J, Beck P. Hepatic portal venous gas: a report of two cases and a review of the epidemiology, pathogenesis, diagnosis and approach to management. Can. J. Gastroenterol. 21: 309-313 (2007). *

• Amarapurkar A, Ghansar T. Fatty liver: experience from western India. Ann. Hepatol. 6: 37-40 (2007). *

• Amela-Peris R, Aladro Y, Conde-Sendin MA, Alemany-Rodriguez MJ, Munoz-Fernandez C, Reyes-Yanez MP, Deniz-Naranjo MC, Sanchez-Garcia F. Familial multiple sclerosis in Canary Islands. Rev. Neurol. 39: 911-914 (2004).

• Amin J, Wong M. Measles-Mumps-Rubella immunisation, autism and inflammatory bowel disease: update. CDI: Current Issues in Immunisation 23: 222 [http://www.cda.gov.au/pubs/cdi/1999/cdi2308/pdf/cdi2308e.pdf] (1999). *

• Aminzadeh KK, Etminan M. Dental amalgam and multiple sclerosis: a systematic review and meta-analysis. J. Public Health Dent. 67: 64-66 (2007).

• Amoli MM, Garcia-Porrua C, Ollier WE, Gonzalez-Gay MA. Lack of association between macrophage migration inhibitory factor gene polymorphism and giant cell arteritis. J. Rheumatol. 32: 74-76 (2005).

• Amoli MM, Gonzalez-Gay MA, Zeggini E, Salway F, Garcia-Porrua C, Ollier WE. Epistatic interactions between HLA-DRB1 and interleukin 4, but not interferon-gamma, increase susceptibility to giant cell arteritis. J. Rheumatol. 31: 2413-2417 (2004). *

• Amoli MM, Salway F, Ollier WE, Gonzalez-Gay MA. MCP-1 gene haplotype association in biopsy proven giant cell arteritis. J. Rheumatol. 32: 507-510 (2005).

• Amos CI, Chen WV, Lee A, Li W, Kern M, Lundsten R, Batliwalla F, Wener M, Remmers E, Kastner DA, Criswell LA, Seldin MF, Gregersen PK. High-density SNP analysis of 642 Caucasian families with rheumatoid arthritis identifies two new linkage regions on 11p12 and 2q33. Genes Immun. 7: 277-286 (2006). *

• Amos CI, Chen WV, Remmers E, Siminovitch KA, Seldin MF, Criswell LA, Lee AT, John S, Shephard ND, Worthington J, Cornelis F, Plenge RM, Begovich AB, Dyer TD, Kastner DL, Gregersen PK. Data for Genetic Analysis Workshop (GAW) 15 Problem 2, genetic causes of rheumatoid arthritis and associated traits. BMC Proc. 1 Suppl. 1: S3 (2007). *

• Amos CI, Chen WV, Seldin MF, Remmers EF, Taylor KE, Criswell LA, Lee AT, Plenge RM, Kastner DL, Gregersen PK. Data for Genetic Analysis Workshop 16 Problem 1, association analysis of rheumatoid arthritis data. BMC Proc. 3 Suppl. 7: S2 (2009). *

• Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, Bueno-de-Mesquita HB, Gross M, Helzlsouer K, Jacobs EJ, Lacroix A, Zheng W, Albanes D, Bamlet W, Berg CD, Berrino F, Bingham S, Buring JE, Bracci PM, et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat. Genet. 41: 986-990 (2009). *

• An P, Thio CL, Kirk GD, Donfield S, Goedert JJ, Winkler CA. Regulatory polymorphisms in the interleukin-18 promoter are associated with hepatitis C virus clearance. J. Infect. Dis. 198: 1159-1165 (2008). *

• An P, Winkler CA. Host genes associated with HIV/AIDS: advances in gene discovery. Trends Genet. Feb 9 [Epub ahead of print] (2010). *

• Ananthakrishnan AN, McGinley EL, Saeian K, Binion DG. Trends in ambulatory and emergency room visits for inflammatory bowel diseases in the United States: 1994-2005. Am. J. Gastroenterol. Oct 6 [Epub ahead of print] (2009). *

• Anastassopoulou CG, Kostrikis LG. The impact of human allelic variation on HIV-1 disease. Curr. HIV Res. 1: 185-203 (2003).

• Andersohn F, Waring M, Garbe E. Risk of ischemic stroke in patients with Crohn's disease: a population-based nested case-control study. Inflamm. Bowel Dis. Dec 14 [Epub ahead of print] (2009).

• Anderson LA, Gadalla S, Morton LM, Landgren O, Pfeiffer R, Warren JL, Berndt SI, Ricker W, Parsons R, Engels EA. Population-based study of autoimmune conditions and the risk of specific lymphoid malignancies. Int. J. Cancer 125: 398-405 (2009). *

• Anderson LA, Pfeiffer RM, Landgren O, Gadalla S, Berndt SI, Engels EA. Risks of myeloid malignancies in patients with autoimmune conditions. Br. J. Cancer 100: 822-828 (2009). *

• Andreassen H, Rungby J, Dahlerup JF, Mosekilde L. Inflammatory bowel disease and osteoporosis. Scand. J. Gastroenterol. 32: 1247-1255 (1997).

• Andres PG, Friedman LS. Epidemiology and the natural course of inflammatory bowel disease. Gastroenterol. Clin. North Am. 28: 255-281, vii (1999).

• Andreu-Ballester JC, Perez-Griera J, Ballester F, Colomer-Rubio E, Ortiz-Tarin I, Penarroja Otero C. Secretory immunoglobulin A (sIgA) deficiency in serum of patients with GALTectomy (appendectomy and tonsillectomy). Clin. Immunol. 123: 289-297 (2007). *

• Angel B, Santos JL, Carrasco E, Albala C, Perez-Bravo F. Vitamin D receptor polymorphism and susceptibility to type 1 diabetes in Chilean subjects: a case-parent study. Eur. J. Epidemiol. 19: 1085-1087 (2004). *

• Anlar B, Kose G, Gurer Y, Altunbasak S, Haspolat S, Okan M. Changing epidemiological features of subacute sclerosing panencephalitis. Infection 29: 192-195 (2001).

• Aoki A, Kirino Y, Ishigatsubo Y, Senuma A, Nagaoka S. Liver involvement in primary Sjogren's syndrome. Nihon Rinsho Meneki Gakkai Kaishi 27: 397-401 (2004).

• Aozasa K, Takakuwa T, Hongyo T, Yang WI. Nasal NK/T-cell lymphoma: epidemiology and pathogenesis. Int. J. Hematol. 87: 110-117 (2008). *

• Apostolakis S, Baritaki S, Krambovitis E, Spandidos DA. Distribution of HIV/AIDS protective SDF1, CCR5 and CCR2 gene variants within Cretan population. J. Clin. Virol. 34: 310-314 (2005).

• Appleyard CB, Hernandez G, Rios-Bedoya CF. Basic epidemiology of inflammatory bowel disease in Puerto Rico. Inflamm. Bowel Dis. 10: 106-111 (2004). *

• Ardaillou R, Le Gall JY. Mass neonatal screening using biological testing. Gynecol. Obstet. Fertil. 35: 367-374 (2007).

• Arden NK, Cooper C. Osteoporosis in patients with inflammatory bowel disease. Gut 50: 9-10 (2002). *

• Ardizzone S. Ulcerative colitis. Orphanet encyclopedia [http://www.orpha.net/data/patho/GB/uk-UC.pdf] (2003). *

• Ardoin SP, Schanberg LE. The management of pediatric systemic lupus erythematosus. Nat. Clin. Pract. Rheumatol. 1: 82-92 (2005). *

• Argo CK, Caldwell SH. Epidemiology and natural history of non-alcoholic steatohepatitis. Clin. Liver Dis. 13: 511-531 (2009).

• Arias-Vasquez A, Isaacs A, Aulchenko YS, Hofman A, Oostra BA, Breteler M, van Duijn CM. The cholesteryl ester transfer protein (CETP) gene and the risk of Alzheimer's disease. Neurogenetics 8: 189-193 (2007).

• Aribi M. Candidate genes implicated in type 1 diabetes susceptibility. Curr. Diabetes Rev. 4: 110-121 (2008).

• Aron Y, Swierczewski E, Lockhart A. A simple and rapid micromethod for genomic DNA extraction from jugal epithelial cells. Application to human lymphocyte antigen typing in one large family of atopic/asthmatic probands. Allergy 49: 788-790 (1994).

• Arya G, Balistreri WF. Pediatric liver disease in the United States: epidemiology and impact. J. Gastroenterol. Hepatol. 17: 521-525 (2002). *

• Ascherio A, Munger K. Epidemiology of multiple sclerosis: from risk factors to prevention. Semin. Neurol. 28: 17-28 (2008).

• Ascherio A, Munger KL. Environmental risk factors for multiple sclerosis. Part I: the role of infection. Ann. Neurol. 61: 288-299 (2007).

• Ascherio A, Zhang SM, Hernan MA, Olek MJ, Coplan PM, Brodovicz K, Walker AM. Hepatitis B vaccination and the risk of multiple sclerosis. N. Engl. J. Med. 344: 327-332 (2001). *

• Ashwood P, Enstrom A, Krakowiak P, Hertz-Picciotto I, Hansen RL, Croen LA, Ozonoff S, Pessah IN, de Water JV. Decreased transforming growth factor beta1 in autism: a potential link between immune dysregulation and impairment in clinical behavioral outcomes. J. Neuroimmunol. 204: 149-153 (2008).

• Askling J, Bongartz T. Malignancy and biologic therapy in rheumatoid arthritis. Curr. Opin. Rheumatol. 20: 334-339 (2008).

• Askling J, Brandt L, Lapidus A, Karlen P, Bjorkholm M, Lofberg R, Ekbom A. Risk of haematopoietic cancer in patients with inflammatory bowel disease. Gut 54: 617-622 (2005). *

• Askling J, Dickman PW, Karlen P, Brostrom O, Lapidus A, Lofberg R, Ekbom A. Colorectal cancer rates among first-degree relatives of patients with inflammatory bowel disease: a population-based cohort study. Lancet 357: 262-266 (2001). *

• Askling J, Dickman PW, Karlen P, Brostrom O, Lapidus A, Lofberg R, Ekbom A. Family history as a risk factor for colorectal cancer in inflammatory bowel disease. Gastroenterology 120: 1356-1362 (2001). *

• Askling J, Dixon W. The safety of anti-tumour necrosis factor therapy in rheumatoid arthritis. Curr. Opin. Rheumatol. 20: 138-144 (2008).

• Atkinson TP, Balish MF, Waites KB. Epidemiology, clinical manifestations, pathogenesis and laboratory detection of Mycoplasma pneumoniae infections. FEMS Microbiol. Rev. 32: 956-973 (2008). *

• Atladottir HO, Pedersen MG, Thorsen P, Mortensen PB, Deleuran B, Eaton WW, Parner ET. Association of family history of autoimmune diseases and autism spectrum disorders. Pediatrics 124: 687-694 (2009). *

• Attia J, Ioannidis JP, Thakkinstian A, McEvoy M, Scott RJ, Minelli C, Thompson J, Infante-Rivard C, Guyatt G. How to use an article about genetic association. A: Background concepts. JAMA 301: 74-81 (2009). *

• Augood C, Chakravarthy U, Young I, Vioque J, de Jong PT, Bentham G, Rahu M, Seland J, Soubrane G, Tomazzoli L, Topouzis F, Vingerling JR, Fletcher AE. Oily fish consumption, dietary docosahexaenoic acid and eicosapentaenoic acid intakes, and associations with neovascular age-related macular degeneration. Am. J. Clin. Nutr. 88: 398-406 (2008). *

• Augustin M, Glaeske G, Radtke MA, Christophers E, Reich K, Schafer I. Epidemiology and comorbidity of psoriasis in children. Br. J. Dermatol. Nov 18 [Epub ahead of print] (2009). *

• Aulchenko YS, Hoppenbrouwers IA, Ramagopalan SV, Broer L, Jafari N, Hillert J, Link J, Lundstrom W, Greiner E, Dessa Sadovnick A, Goossens D, Broeckhoven CV, Del-Favero J, Ebers GC, Oostra BA, van Duijn CM, Hintzen RQ. Genetic variation in the KIF1B locus influences susceptibility to multiple sclerosis. Nat. Genet. 40: 1402-1403 (2008). *

• Autret-Leca E, Bensouda-Grimaldi L, Jonville-Bera AP, Beau-Salinas F. Pharmacovigilance of vaccines. Arch. Pediatr. 13: 175-180 (2006).

• Autret-Leca E, Jonville-Bera AP, Beau-Salinas F. Vaccines pharmacovigilance. Rev. Prat. 54: 526-531 (2004).

• Auvin S, Molinie F, Gower-Rousseau C, Brazier F, Merle V, Grandbastien B, Marti R, Lerebours E, Dupas JL, Colombel JF, Salomez JL, Cortot A, Turck D. Incidence, clinical presentation and location at diagnosis of pediatric inflammatory bowel disease: a prospective population-based study in Northern France (1988-1999). J. Pediatr. Gastroenterol. Nutr. 41: 49-55 (2005). *

• Avery CL, Monda KL, North KE. Genetic association studies and the effect of misclassification and selection bias in putative confounders. BMC Proc. 3 Suppl. 7: S48 (2009). *

• Ayanlowo O, Olumide YM, Akinkugbe A, Ahamneze N, Otike-Odibi BI, Ekpudu VI, Nnaji T, Akolawole NA. Characteristics of vitiligo in Lagos, Nigeria. West Afr. J. Med. 28: 118-121 (2009).

• Azevedo NF, Huntington J, Goodman KJ. The epidemiology of Helicobacter pylori and public health implications. Helicobacter 14 Suppl. 1: 1-7 (2009).

• Azfar RS, Gelfand JM. Psoriasis and metabolic disease: epidemiology and pathophysiology. Curr. Opin. Rheumatol. 20: 416-422 (2008). *

• Babu GR. Comment on "development and validation of a colon cancer risk assessment tool for patients undergoing colonoscopy". Am. J. Gastroenterol. 104: 3102-3103 (2009).

• Bachmann S, Kesselring J. Multiple sclerosis and infectious childhood diseases. Neuroepidemiology 17: 154-160 (1998).

• Baenziger S, Heikenwalder M, Johansen P, Schlaepfer E, Hofer U, Miller RC, Diemand S, Honda K, Kundig TM, Aguzzi A, Speck RF. Triggering TLR7 in mice induces immune activation and lymphoid system disruption, resembling HIV-mediated pathology. Blood 113: 377-388 (2009). *

• Bager P, Arnved J, Ronborg S, Wohlfahrt J, Poulsen LK, Westergaard T, Petersen HW, Kristensen B, Thamsborg S, Roepstorff A, Kapel C, Melbye M. Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial. J. Allergy Clin. Immunol. Oct 2 [Epub ahead of print] (2009).

• Bager P, Nielsen NM, Bihrmann K, Frisch M, Wohlfart J, Koch-Henriksen N, Melbye M, Westergaard T. Sibship characteristics and risk of multiple sclerosis: a nationwide cohort study in Denmark. Am. J. Epidemiol. 163: 1112-1117 (2006). *

• Bai JL, Zheng MH, Xia X, Ter-Minassian M, Chen YP, Chen F. MTHFR C677T polymorphism contributes to prostate cancer risk among Caucasians: a meta-analysis of 3511 cases and 2762 controls. Eur. J. Cancer 45: 1443-1449 (2009). *

• Baier LJ, Permana PA, Traurig M, Dobberfuhl A, Wiedrich C, Sutherland J, Thuillez P, Luczy-Bachman G, Hara M, Horikawa Y, Hinokio Y, Hanson RL, Bogardus C. Mutations in the genes for hepatocyte nuclear factor (HNF)-1alpha, -4alpha, -1beta, and -3beta; the dimerization cofactor of HNF-1; and insulin promoter factor 1 are not common causes of early-onset type 2 diabetes in Pima Indians. Diabetes Care 23: 302-304 (2000). *

• Baker PI, Love DR, Ferguson LR. Role of gut microbiota in Crohn's disease. Expert Rev. Gastroenterol. Hepatol. 3: 535-546 (2009).

• Baksh MF, Balding DJ, Vyse TJ, Whittaker JC. A likelihood ratio approach to family-based association studies with covariates. Ann. Hum. Genet. 70: 131-139 (2006). *

• Balani AR, Grendell JH. Drug-induced pancreatitis: incidence, management and prevention. Drug Saf. 31: 823-837 (2008).

• Balic I, Angel B, Codner E, Carrasco E, Perez-Bravo F. Association of CTLA-4 polymorphisms and clinical-immunologic characteristics at onset of type 1 diabetes mellitus in children. Hum. Immunol. 70: 116-120 (2009).

• Balistreri WF. Genetic liver disease. 54th Annual Meeting of the American Association for the Study of Liver Diseases (2003).

• Bambha K, Kim WR, Talwalkar J, Torgerson H, Benson JT, Therneau TM, Loftus EV Jr, Yawn BP, Dickson ER, Melton LJ 3rd. Incidence, clinical spectrum, and outcomes of primary sclerosing cholangitis in a United States community. Gastroenterology 125: 1364-1369 (2003). *

• Bansback N, Brennan A, Symmons D, Nixon R, Madan J, Harrison M, Watson K. Comment on: modelling the cost effectiveness of TNF-alpha antagonists in the management of rheumatoid arthritis: results from the British Society for Rheumatology Biologics Registry: reply. Rheumatology (Oxford) 47: 1107 (2008).

• Banus S, Bottema RW, Siezen CL, Vandebriel RJ, Reimerink J, Mommers M, Koppelman GH, Hoebee B, Thijs C, Postma DS, Kimman TG, Stelma FF. A Toll-like receptor 4 polymorphism is associated with the response to whole-cell pertussis vaccination in children from the KOALA study. Clin. Vaccine Immunol. 14: 1377-1380 (2007).

• Bao Y, Spiegelman D, Li R, Giovannucci E, Fuchs CS, Michaud DS. History of peptic ulcer disease and pancreatic cancer risk in men. Gastroenterology 138: 541-549 (2010). *

• Barahmani N, Schabath MB, Duvic M; National Alopecia Areata Registry. History of atopy or autoimmunity increases risk of alopecia areata. J. Am. Acad. Dermatol. 61: 581-591 (2009).

• Barbut F, Gariazzo B, Bonne L, Lalande V, Burghoffer B, Luiuz R, Petit JC. Clinical features of Clostridium difficile-associated infections and molecular characterization of strains: results of a retrospective study, 2000-2004. Infect. Control Hosp. Epidemiol. 28: 131-139 (2007). *

• Barcellos LF, Kamdar BB, Ramsay PP, Deloa C, Lincoln RR, Caillier S, Schmidt S, Haines JL, Pericak-Vance MA, Oksenberg JR, Hauser SL. Clustering of autoimmune diseases in families with a high-risk for multiple sclerosis: a descriptive study. Lancet Neurol. 5: 924-931 (2006).

• Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet. 5: e1000696 (2009). *

• Barcellos LF, Ramsay PP, Caillier SJ, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston DA, Gabatto P, Hauser SL, Oksenberg JR. Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. Genes Immun. 9: 493-500 (2008). *

• Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Ucelli A, Savettieri G, Lincoln RL, Deloa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum. Mol. Genet. 15: 2813-2824 (2006). *

• Barchana M, Liphshitz I, Rozen P. Trends in colorectal cancer incidence and mortality in the Israeli Jewish ethnic populations. Fam. Cancer 3: 207-214 (2004). *

• Barlow C, Cooke D, Mulligan K, Beck E, Newman S. A critical review of self-management and educational interventions in inflammatory bowel disease. Gastroenterol. Nurs. 33: 11-18 (2010).

• Barnes KC, Grant A, Gao P, Baltadjieva D, Berg T, Chi P, Zhang S, Zambelli-Weiner A, Ehrlich E, Zardkoohi O, Brummet ME, Stockton M, Watkins T, Gao L, Gittens M, Wills-Karp M, Cheadle C, Beck LA, Beaty TH, Becker KG, Garcia JG, Mathias RA. Polymorphisms in the novel gene acyloxyacyl hydroxylase (AOAH) are associated with asthma and associated phenotypes. J. Allergy Clin. Immunol. 118: 70-77 (2006). *

• Barnetche T, Constantin A, Gourraud PA, Abbal M, Garnier JG, Cantagrel A, Cambon-Thomsen A. Microsatellite typing of the human leucocyte antigen region: analytical approach and contribution to rheumatoid arthritis immunogenetic studies. Tissue Antigens 68: 390-398 (2006). *

• Barton A, Eyre S, Ke X, Hinks A, Bowes J, Flynn E, Martin P; YEAR Consortium; BIRAC Consortium, Wilson AG, Morgan AW, Emery P, Steer S, Hocking LJ, Reid DM, Harrison P, Wordsworth P, Thomson W, Worthington J. Identification of AF4/FMR2 family, member 3 (AFF3) as a novel rheumatoid arthritis susceptibility locus and confirmation of two further pan-autoimmune susceptibility genes. Hum. Mol. Genet. 18: 2518-2522 (2009). *

• Barton A, Eyre S, Myerscough A, Brintnell B, Ward D, Ollier WE, Lorentzen JC, Klareskog L, Silman A, John S, Worthington J; Arthritis Rheumatism Campaign National Repository. High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. Hum. Mol. Genet. 10: 1901-1906 (2001). *

• Barton A, Lamb R, Symmons D, Silman A, Thomson W, Worthington J, Donn R. Macrophage migration inhibitory factor (MIF) gene polymorphism is associated with susceptibility to but not severity of inflammatory polyarthritis. Genes Immun. 4: 487-491 (2003). *

• Barton A, Myerscough A, John S, Gonzalez-Gay M, Ollier W, Worthington J. A single nucleotide polymorphism in exon 1 of cytotoxic T-lymphocyte-associated-4 (CTLA-4) is not associated with rheumatoid arthritis. Rheumatology (Oxford) 39: 63-66 (2000). *

• Barton A, Platt H, Salway F, Symmons D, Lunt M, Worthington J, Silman A. Polymorphisms in the mannose binding lectin (MBL) gene are not associated with radiographic erosions in rheumatoid or inflammatory polyarthritis. J. Rheumatol. 31: 442-447 (2004). *

• Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Gibbons L, Plant D; Wellcome Trust Case Control Consortium, Wilson AG, Marinou I, Morgan A, Emery P; YEAR consortium, Steer S, Hocking L, Reid DM, Wordsworth P, Harrison P, Worthington J. Re-evaluation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying susceptibility. Hum. Mol. Genet. 17: 2274-2279 (2008). *

• Barton A, Thomson W, Ke X, Eyre S, Hinks A, Bowes J, Plant D, Gibbons LJ; Wellcome Trust Case Control Consortium; YEAR Consortium; BIRAC Consortium. Rheumatoid arthritis susceptibility loci at chromosomes 10p15, 12q13 and 22q13. Nat. Genet. 40: 1156-1159 (2008). *

• Bastian HM, Alarcon GS, Roseman JM, McGwin G Jr, Vila LM, Fessler BJ, Reveille JD. Systemic lupus erythematosus in a multiethnic US cohort (LUMINA) XL II: factors predictive of new or worsening proteinuria. Rheumatology (Oxford) 46: 683-689 (2007). *

• Basu D, Lopez I, Kulkarni A, Sellin JH. Impact of race and ethnicity on inflammatory bowel disease. Am. J. Gastroenterol. 100: 2254-2261 (2005). *

• Baumgart DC. What's new in inflammatory bowel disease in 2008? World J. Gastroenterol. 14: 329-330 (2008). *

• Baumhoer D, Tornillo L, Stadlmann S, Roncalli M, Diamantis EK, Terracciano LM. Glypican 3 expression in human nonneoplastic, preneoplastic, and neoplastic tissues: a tissue microarray analysis of 4,387 tissue samples. Am. J. Clin. Pathol. 129: 899-906 (2008). *

• Baurecht H, Irvine AD, Novak N, Illig T, Buhler B, Ring J, Wagenpfeil S, Weidinger S. Toward a major risk factor for atopic eczema: meta-analysis of filaggrin polymorphism data. J. Allergy Clin. Immunol. 120: 1406-1412 (2007). *

• Baussano I, Tardivo I, Bellezza-Fontana R, Forneris MP, Lezo A, Anfossi L, Castello M, Aleksandar V, Bignamini E. Neonatal screening for cystic fibrosis does not affect time to first infection with Pseudomonas aeruginosa. Pediatrics 118: 888-895 (2006). *

• Baxter NN, Tepper JE, Durham SB, Rothenberger DA, Virnig BA. Increased risk of rectal cancer after prostate radiation: a population-based study. Gastroenterology 128: 819-824 (2005). *

• Baylin A, Ruiz-Narvaez E, Kraft P, Campos H. alpha-Linolenic acid, Delta6-desaturase gene polymorphism, and the risk of nonfatal myocardial infarction. Am. J. Clin. Nutr. 85: 554-560 (2007). *

• Bazrafshani MR, Hajeer AH, Ollier WE, Thornhill MH. IL-1B and IL-6 gene polymorphisms encode significant risk for the development of recurrent aphthous stomatitis (RAS). Genes Immun. 3: 302-305 (2002). *

• Becker A, Smulders YM, van Guldener C, Stehouwer CD. Epidemiology of homocysteine as a risk factor in diabetes. Metab. Syndr. Relat. Disord. 1: 105-120 (2003).

• Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Ch Stricker BH. Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy. Pharmacoepidemiol. Drug Saf. 19: 75-81 (2009).

• Becker ML, Visser LE, van Schaik RH, Hofman A, Uitterlinden AG, Stricker BH. Genetic variation in the organic cation transporter 1 is associated with metformin response in patients with diabetes mellitus. Pharmacogenomics J. 9: 242-247 (2009).

• Bedogni G, Bellentani S. Fatty liver: how frequent is it and why? Ann. Hepatol. 3: 63-65 (2004). *

• Befeler AS. New developments in hepatocellular carcinoma. 54th Annual Meeting of the American Association for the Study of Liver Diseases (2003).

• Belfort R, Berria R, Cornell J, Cusi K. Fenofibrate reduces systemic inflammation markers independent of its effects on lipid and glucose metabolism in patients with the metabolic syndrome. J. Clin. Endocrinol. Metab. Jan 8 [Epub ahead of print] (2010). *

• Bell BP, Manos MM, Zaman A, Terrault N, Thomas A, Navarro VJ, Dhotre KB, Murphy RC, Van Ness GR, Stabach N, Robert ME, Bower WA, Bialek SR, Sofair AN. The epidemiology of newly diagnosed chronic liver disease in gastroenterology practices in the United States: results from population-based surveillance. Am. J. Gastroenterol. 103: 2727-2736 (2008). *

• Belle SH, Beringer KC, Detre KM. An update on liver transplantation in the United States: recipient characteristics and outcome. Clin. Transpl. 1995: 19-33 (1995).

• Bellentani S, Marino M. Epidemiology and natural history of non-alcoholic fatty liver disease (NAFLD). Ann. Hepatol. 8 Suppl. 1: S4-S8 (2009). *

• Belousova E. Epidemiology of inflammatory bowel disease in Russia. Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, p. 31 (2006). *

• Benchimol EI, Guttmann A, Griffiths AM, Rabeneck L, Mack DR, Brill H, Howard J, Guan J, To T. Increasing incidence of paediatric inflammatory bowel disease in Ontario, Canada: evidence from health administrative data. Gut 58: 1490-1497 (2009).

• Benchimol EI, Ward LM, Gallagher J, Rauch F, Barrowman N, Warren J, Beedle S, Mack DR. Effect of calcium and vitamin D supplementation on bone mineral density in children with inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 45: 538-545 (2007). *

• Bene L, Sapi Z, Bajtai A, Buzas E, Szentmihalyi A, Arato A, Tulassay Z, Falus A. Partial protection against dextran sodium sulphate induced colitis in histamine-deficient, histidine decarboxylase knockout mice. J. Pediatr. Gastroenterol. Nutr. 39: 171-176 (2004). *

• Benjamin EJ, Rice KM, Arking DE, Pfeufer A, van Noord C, Smith AV, Schnabel RB, Bis JC, Boerwinkle E, Sinner MF, Dehghan A, Lubitz SA, D'Agostino Sr RB, Lumley T, Ehret GB, Heeringa J, Aspelund T, Newton-Cheh C, Larson MG, Marciante KD, Soliman EZ, et al. Variants in ZFHX3 are associated with atrial fibrillation in individuals of European ancestry. Nat. Genet. 41: 879-881 (2009). *

• Benjaminov FS, Heathcote J. Liver disease in pregnancy. Am. J. Gastroenterol. 99: 2479-2488 (2004). *

• Bercion R, Demartin M, Recio C, Massamba PM, Frank T, Escriba JM, Grimont F, Grimont PA, Weill FX. Molecular epidemiology of multidrug-resistant Shigella dysenteriae type 1 causing dysentery outbreaks in Central African Republic, 2003-2004. Trans. R. Soc. Trop. Med. Hyg. 100: 1151-1158 (2006).

• Berentsen S, Ulvestad E, Langholm R, Beiske K, Hjorth-Hansen H, Ghanima W, Sorbo JH, Tjonnfjord GE. Primary chronic cold agglutinin disease: a population based clinical study of 86 patients. Haematologica 91: 460-466 (2006). *

• Bergamaschi G, Di Sabatino A, Albertini R, Ardizzone S, Biancheri P, Bonetti E, Cassinotti A, Cazzola P, Markopoulos K, Massari A, Rosti V, Bianchi Porro G, Corazza GR. Prevalence and pathogenesis of anemia in inflammatory bowel disease. Influence of anti-tumor necrosis factor-alpha treatment. Haematologica Oct 8 [Epub ahead of print] (2009). *

• Berger K, Stogbauer F, Stoll M, Wellmann J, Huge A, Cheng S, Kessler C, John U, Assmann G, Ringelstein EB, Funke H. The glu298asp polymorphism in the nitric oxide synthase 3 gene is associated with the risk of ischemic stroke in two large independent case-control studies. Hum. Genet. 121: 169-178 (2007). *

• Bergholdt R, Larsen ZM, Andersen NA, Johannesen J, Kristiansen OP, Mandrup-Poulsen T, Nerup J, Pociot F; Danish Study Group of IDDM in Childhood; Danish IDDM Epidemiology and Genetics Group. Characterization of new polymorphisms in the 5' UTR of the human interleukin-1 receptor type 1 (IL1R1) gene: linkage to type 1 diabetes and correlation to IL-1RI plasma level. Genes Immun. 1: 495-500 (2000). *

• Bergmann MM, Jacobs EJ, Hoffmann K, Boeing H. Agreement of self-reported medical history: comparison of an in-person interview with a self-administered questionnaire. Eur. J. Epidemiol. 19: 411-416 (2004).

• Berkun Y, Padeh S. Environmental factors and the geoepidemiology of juvenile idiopathic arthritis. Autoimmun. Rev. Nov 21 [Epub ahead of print] (2009).

• Bermejo JL. Gene-environment interactions and familial relative risks. Hum. Hered. 66: 170-179 (2008).

• Bermejo JL, Eng C, Hemminki K. Cancer characteristics in Swedish families fulfilling criteria for hereditary nonpolyposis colorectal cancer. Gastroenterology 129: 1889-1899 (2005). *

• Bernatsky S, Clarke A, Gladman DD, Urowitz M, Fortin PR, Barr SG, Senecal JL, Zummer M, Edworthy S, Sibley J, Pope J, Ensworth S, Ramsey-Goldman R, Hanly JG. Mortality related to cerebrovascular disease in systemic lupus erythematosus. Lupus 15: 835-839 (2006).

• Bernatsky S, Hudson M, Suissa S. Anti-rheumatic drug use and risk of serious infections in rheumatoid arthritis. Rheumatology (Oxford) 46: 1157-1160 (2007). *

• Bernatsky S, Lee JL, Rahme E. Non-Hodgkin's lymphoma - meta-analyses of the effects of corticosteroids and non-steroidal anti-inflammatories. Rheumatology (Oxford) 46: 690-694 (2007). *

• Bernatsky S, Pineau CA, Lee JL, Clarke AE. Headache, Raynaud's syndrome and serotonin receptor agonists in systemic lupus erythematosus. Lupus 15: 671-674 (2006).

• Bernatsky S, Ramsey-Goldman R, Clarke A. Malignancy and autoimmunity. Curr. Opin. Rheumatol. 18: 129-134 (2006).

• Berndt SI, Dodson JL, Huang WY, Nicodemus KK. A systematic review of vitamin D receptor gene polymorphisms and prostate cancer risk. J. Urol. 175: 1613-1623 (2006).

• Berndt SI, Huang WY, Chatterjee N, Yeager M, Welch R, Chanock SJ, Weissfeld JL, Schoen RE, Hayes RB. Transforming growth factor beta 1 (TGFB1) gene polymorphisms and risk of advanced colorectal adenoma. Carcinogenesis 28: 1965-1970 (2007). *

• Berndt SI, Huang WY, Yeager M, Weissfeld JL, Chanock SJ, Hayes RB. Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia. Cancer Causes Control 20: 487-490 (2009). *

• Bernstein CN, Blanchard JF, Metge C, Yogendran M. Does the use of 5-aminosalicylates in inflammatory bowel disease prevent the development of colorectal cancer? Am. J. Gastroenterol. 98: 2784-2788 (2003). *

• Bernstein CN, Nugent Z, Longobardi T, Blanchard JF. Isotretinoin is not associated with inflammatory bowel disease: a population-based case-control study. Am. J. Gastroenterol. 104: 2774-2778 (2009). *

• Bernstein CN, Shanahan F. Disorders of a modern lifestyle-reconciling the epidemiology of inflammatory bowel diseases. Gut 57: 1185-1191 (2008).

• Bernstein CN, Wajda A, Blanchard JF. The incidence of arterial thromboembolic diseases in inflammatory bowel disease: a population-based study. Clin. Gastroenterol. Hepatol. 6: 41-45 (2008).

• Bernstein CN, Wajda A, Svenson LW, MacKenzie A, Koehoorn M, Jackson M, Fedorak R, Israel D, Blanchard JF. The epidemiology of inflammatory bowel disease in Canada: a population-based study. Am. J. Gastroenterol. 101: 1559-1568 (2006). *

• Bernstein CN, Wang MH, Sargent M, Brant SR, Collins MT. Testing the interaction between NOD-2 status and serological response to Mycobacterium paratuberculosis in cases of inflammatory bowel disease. J. Clin. Microbiol. 45: 968-971 (2007). *

• Bertrandt J, Klos A, Debski B. Polyunsaturated fatty acid (PUFA) changes in serum and liver of undernourished rats given dietary vitamin B6 supplementation. J. Nutr. Sci. Vitaminol. (Tokyo) 51: 129-134 (2005).

• Betterle C, Zanchetta R. Update on autoimmune polyendocrine syndromes (APS). Acta Biomed. Ateneo. Parmense. 74: 9-33 (2003).

• Betz RC, Konig K, Flaquer A, Redler S, Eigelshoven S, Kortum AK, Hanneken S, Hillmer A, Tuting T, Lambert J, De Weert J, Kruse R, Lutz G, Blaumeiser B, Nothen MM. The R620W polymorphism in PTPN22 confers general susceptibility for the development of alopecia areata. Br. J. Dermatol. 158: 389-391 (2008). *

• Beulens JW, Rimm EB, Hendriks HF, Hu FB, Manson JE, Hunter DJ, Mukamal KJ. Alcohol consumption and type 2 diabetes: influence of genetic variation in alcohol dehydrogenase. Diabetes 56: 2388-2394 (2007). *

• Bezemer ID, Doggen CJ, Vos HL, Rosendaal FR. No association between the common MTHFR 677C->T polymorphism and venous thrombosis: results from the MEGA study. Arch. Intern. Med. 167: 497-501 (2007). *

• Bhardwaj S, Canlas K, Kahi C, Temkit M, Molleston J, Ober M, Howenstine M, Kwo PY. Hepatobiliary abnormalities and disease in cystic fibrosis: epidemiology and outcomes through adulthood. J. Clin. Gastroenterol. Jun 11 [Epub ahead of print] (2009).

• Bhat A, Naguwa S, Cheema G, Gershwin ME. The epidemiology of transverse myelitis. Autoimmun. Rev. Dec 22 [Epub ahead of print] (2009).

• Bhatnagar S, Tandon N. Diagnosis of celiac disease. Indian J. Pediatr. 73: 703-709 (2006). *

• Bhutta ZA. Micronutrient needs of malnourished children. Curr. Opin. Clin. Nutr. Metab. Care 11: 309-314 (2008).

• Bi Y, Du Z, Han Y, Guo Z, Tan Y, Zhu Z, Yang R. Yersinia pestis and host macrophages: immunodeficiency of mouse macrophages induced by YscW. Immunology 128: e406-e417 (2009). *

• Bi Y, Du Z, Yang H, Guo Z, Tan Y, Zhu Z, Yang R. Reduced apoptosis of mouse macrophages induced by yscW mutant of Yersinia pestis results from the reduced secretion of YopJ and relates to caspase-3 signal pathway. Scand. J. Immunol. 70: 358-367 (2009). *

• Bi Y, Liu G, Yang R. Th17 cell induction and immune regulatory effects. J. Cell. Physiol. 211: 273-278 (2007). *

• Bianchi ML, Bardella MT. Bone in celiac disease. Osteoporos. Int. 19: 1705-1716 (2008). *

• Bianchi V, Maconi G, Ardizzone S, Colombo E, Ferrara E, Russo A, Tenchini ML, Porro GB. Association of NOD2/CARD15 mutations on Crohn's disease phenotype in an Italian population. Eur. J. Gastroenterol. Hepatol. 19: 217-223 (2007).

• Bielinski SJ, Pankow JS, Boerwinkle E, Bray MS, Kao WH, Folsom AR. Lack of association between uncoupling protein-2 Ala55Val polymorphism and incident diabetes in the atherosclerosis risk in communities study. Acta Diabetol. 45: 179-182 (2008).

• Bielinski SJ, Pankow JS, Miller MB, Hopkins PN, Eckfeldt JH, Hixson J, Liu Y, Register T, Myers RH, Arnett DK. Circulating MCP-1 levels shows linkage to chemokine receptor gene cluster on chromosome 3: the NHLBI Family Heart Study follow-up examination. Genes Immun. 8: 684-690 (2007). *

• Biggioggero M, Meroni PL. The geoepidemiology of the antiphospholipid antibody syndrome. Autoimmun. Rev. Nov 19 [Epub ahead of print] (2009).

• Binder V. Epidemiology of IBD during the twentieth century: an integrated view. Best Pract. Res. Clin. Gastroenterol. 18: 463-479 (2004).

• Binder V. Clinical epidemiology - how important now? Gut 54: 574-575 (2005). *

• Binder V. Genetic epidemiology in inflammatory bowel disease. Dig. Dis. 16: 351-355 (1998).

• Binsaeed AA. Is there a link between seropositivity to Helicobacter pylori and hepatitis A virus? A systematic review. Int. J. Infect. Dis. Jan 6 [Epub ahead of print] (2010).

• Birlea SA, Fain PR, Spritz RA. A Romanian population isolate with high frequency of vitiligo and associated autoimmune diseases. Arch. Dermatol. 144: 310-316 (2008). *

• Birrenbach T, Bocker U. Inflammatory bowel disease and smoking: a review of epidemiology, pathophysiology, and therapeutic implications. Inflamm. Bowel Dis. 10: 848-859 (2004). *

• Bishop DT, Demenais F, Iles MM, Harland M, Taylor JC, Corda E, Randerson-Moor J, Aitken JF, Avril MF, Azizi E, Bakker B, Bianchi-Scarra G, Bressac-de Paillerets B, Calista D, Cannon-Albright LA, Chin-A-Woeng T, Debniak T, Galore-Haskel G, et al. Genome-wide association study identifies three loci associated with melanoma risk. Nat. Genet. 41: 920-925 (2009). *

• Bismuth M, Aguilar-Martinez P, Michel H. Hereditary haemochromatosis. Presse. Med. 32: 1716-1723 (2003).

• Bitton A, Sewitch MJ, Peppercorn MA, deB Edwardes MD, Shah S, Ransil B, Locke SE. Psychosocial determinants of relapse in ulcerative colitis: a longitudinal study. Am. J. Gastroenterol. 98: 2203-2208 (2003). *

• Bjorck S, Brundin C, Lorinc E, Lynch KF, Agardh D. Screening detects a high proportion of celiac disease in young HLA-genotyped children. J. Pediatr. Gastroenterol. Nutr. 50: 49-53 (2010).

• Black S, Teixeira AS, Loh AX, Vinall L, Holloway JW, Hardy R, Swallow DM. Contribution of functional variation in the IL13 gene to allergy, hay fever and asthma in the NSHD longitudinal 1946 birth cohort. Allergy 64: 1172-1178 (2009).

• Blair IA. DNA-adducts with lipid peroxidation products. J. Biol. Chem. 283: 15545-15549 (2008). *

• Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116: 536-547 (2006). *

• Blanchard JF, Bernstein CN, Wajda A, Rawsthorne P. Small-area variations and sociodemographic correlates for the incidence of Crohn's disease and ulcerative colitis. Am. J. Epidemiol. 154: 328-335 (2001). *

• Blank C, Sabri M, Di Lorenzo C. Pediatric gastric and duodenal disorders. Curr. Opin. Gastroenterol. 20: 551-555 (2004).

• Boberg KM. Prevalence and epidemiology of autoimmune hepatitis. Clin. Liver Dis. 6: 347-359 (2002).

• Bochenski J, Placha G, Wanic K, Malecki M, Sieradzki J, Warram JH, Krolewski AS. New polymorphism of ENPP1 (PC-1) is associated with increased risk of type 2 diabetes among obese individuals. Diabetes 55: 2626-2630 (2006). *

• Bodhini D, Radha V, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. The G1057D polymorphism of IRS-2 gene and its relationship with obesity in conferring susceptibility to type 2 diabetes in Asian Indians. Int. J. Obes. (Lond.) 31: 97-102 (2007). *

• Bodhini D, Radha V, Dhar M, Narayani N, Mohan V. The rs12255372(G/T) and rs7903146(C/T) polymorphisms of the TCF7L2 gene are associated with type 2 diabetes mellitus in Asian Indians. Metabolism 56: 1174-1178 (2007). *

• Bodmer M, Meier C, Kraenzlin ME, Meier CR. Risk of fractures with glitazones: a critical review of the evidence to date. Drug Saf. 32: 539-547 (2009).

• Boehncke WH, Boehncke S. Cardiovascular morbidity in psoriasis: epidemiology, pathomechanisms, and clinical consequences. G. Ital. Dermatol. Venereol. 143: 307-313 (2008).

• Bogaert D, Weinberger D, Thompson C, Lipsitch M, Malley R. Impaired innate and adaptive immunity to Streptococcus pneumoniae and its effect on colonization in an infant mouse model. Infect. Immun. 77: 1613-1622 (2009). *

• Bongardt F, Schopfer-Wendels A, Huth C, Heid I, Rathmann W, Martin S, Vollmert C, Holle R, Thorand B, Wichmann HE, Koenig W, Kolb H, Herder C. Genetics of type 2 diabetes: impact of interleukin-6 gene variants. Gesundheitswesen 67 Suppl. 1: 122-126 (2005).

• Bonovas S, Filioussi K, Sitaras NM. Do nonsteroidal anti-inflammatory drugs affect the risk of developing ovarian cancer? A meta-analysis. Br. J. Clin. Pharmacol. 60: 194-203 (2005). *

• Bookman EB, Langehorne AA, Eckfeldt JH, Glass KC, Jarvik GP, Klag M, Koski G, Motulsky A, Wilfond B, Manolio TA, Fabsitz RR, Luepker RV; NHLBI Working Group. Reporting genetic results in research studies: summary and recommendations of an NHLBI working group. Am. J. Med. Genet. A. 140: 1033-1040 (2006).

• Borchers AT, Naguwa SM, Shoenfeld Y, Gershwin ME. The geoepidemiology of systemic lupus erythematosus. Autoimmun. Rev. Dec 23 [Epub ahead of print] (2009).

• Borchers AT, Uibo R, Gershwin ME. The geoepidemiology of type 1 diabetes. Autoimmun. Rev. Dec 4 [Epub ahead of print] (2009).

• Bosetti C, Levi F, Lucchini F, Zatonski WA, Negri E, La Vecchia C. Worldwide mortality from cirrhosis: an update to 2002. J. Hepatol. 46: 827-839 (2007). *

• Bousvaros A, Sylvester F, Kugathasan S, Szigethy E, Fiocchi C, Colletti R, Otley A, Amre D, Ferry G, Czinn SJ, Splawski JB, Oliva-Hemker M, Hyams JS, Faubion WA, Kirschner BS, Dubinsky MC; and the Members of the Challenges in Pediatric IBD Study Groups. Challenges in pediatric inflammatory bowel disease. Inflamm. Bowel Dis. 12: 885-913 (2006). *

• Bowes J, Barton A. Recent advances in the genetics of RA susceptibility. Rheumatology (Oxford) 47: 399-402 (2008). *

• Bowes JD, Potter C, Gibbons LJ, Hyrich K, Plant D, Morgan AW, Wilson AG, Isaacs JD, Worthington J, Barton A; BRAGGSS. Investigation of genetic variants within candidate genes of the TNFRSF1B signalling pathway on the response to anti-TNF agents in a UK cohort of rheumatoid arthritis patients. Pharmacogenet. Genomics 19: 319-323 (2009).

• Boykinova OB, Stoilova YD, Tsvetkova TZ, Baltadjiev IG. Epidemiological, immunological and clinical characteristics of acute hepatitis C. Folia Med. (Plovdiv.) 51: 61-69 (2009).

• Boyles AL, Wilcox AJ, Taylor JA, Shi M, Weinberg CR, Meyer K, Fredriksen A, Ueland PM, Johansen AM, Drevon CA, Jugessur A, Trung TN, Gjessing HK, Vollset SE, Murray JC, Christensen K, Lie RT. Oral facial clefts and gene polymorphisms in metabolism of folate/one-carbon and vitamin A: a pathway-wide association study. Genet. Epidemiol. 33: 247-255 (2009).

• Bozkurt O, de Boer A, Grobbee DE, Kroon AA, Schiffers P, de Leeuw P, Klungel OH. Renin-angiotensin system polymorphisms and the association between use of angiotensin II receptor blockers or angiotensin-converting enzyme inhibitors and the risk of diabetes. J. Renin Angiotensin Aldosterone Syst. 10: 101-108 (2009).

• Bozkurt O, Verschuren WM, van Wieren-de Wijer BM, Knol MJ, de Boer A, Grobbee DE, Geerlings MI, Heerdink ER, Klungel OH. Genetic variation in the renin-angiotensin system modifies the beneficial effects of ACE inhibitors on the risk of diabetes mellitus among hypertensives. J. Hum. Hypertens. 22: 774-780 (2008).

• Bradbury R, Champion A, Reid DW. Poor clinical outcomes associated with a multi-drug resistant clonal strain of Pseudomonas aeruginosa in the Tasmanian cystic fibrosis population. Respirology 13: 886-892 (2008).

• Brand S, Staudinger T, Schnitzler F, Pfennig S, Hofbauer K, Dambacher J, Seiderer J, Tillack C, Konrad A, Crispin A, Goke B, Lohse P, Ochsenkuhn T. The role of Toll-like receptor 4 Asp299Gly and Thr399Ile polymorphisms and CARD15/NOD2 mutations in the susceptibility and phenotype of Crohn's disease. Inflamm. Bowel Dis. 11: 645-652 (2005). *

• Brandt D, Bernstein JA. Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis. Ann. Allergy Asthma Immunol. 96: 526-532 (2006).

• Brant SR. Exposed: the genetic underpinnings of ulcerative colitis relative to Crohn's disease. Gastroenterology 136: 396-399 (2009). *

• Brant SR, McGovern DP. NOD2, not yet: con. Inflamm. Bowel Dis. 11: 507-509 (2005). *

• Brant SR, Nguyen GC. Is there a gender difference in the prevalence of Crohn's disease or ulcerative colitis? Inflamm. Bowel Dis. 14 Suppl. 2: S2-S3 (2008). *

• Brant SR, Panhuysen CI, Nicolae D, Reddy DM, Bonen DK, Karaliukas R, Zhang L, Swanson E, Datta LW, Moran T, Ravenhill G, Duerr RH, Achkar JP, Karban AS, Cho JH. MDR1 Ala893 polymorphism is associated with inflammatory bowel disease. Am. J. Hum. Genet.73: 1282-1292 (2003). *

• Brauchli YB, Jick SS, Curtin F, Meier CR. Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: a population based case-control study. J. Am. Acad. Dermatol. 58: 421-429 (2008).

• Brauchli YB, Jick SS, Curtin F, Meier CR. Association between beta-blockers, other antihypertensive drugs and psoriasis: population-based case-control study. Br. J. Dermatol. 158: 1299-1307 (2008). *

• Brauchli YB, Jick SS, Curtin F, Meier CR. Lithium, antipsychotics, and risk of psoriasis. J. Clin. Psychopharmacol. 29: 134-40 (2009).

• Brauchli YB, Jick SS, Meier CR. Psoriasis and the risk of incident diabetes mellitus: a population-based study. Br. J. Dermatol. 159: 1331-1337 (2008). *

• Brauchli YB, Jick SS, Miret M, Meier CR. Psoriasis and risk of incident myocardial infarction, stroke or transient ischaemic attack: an inception cohort study with a nested case-control analysis. Br. J. Dermatol. 160: 1048-1056 (2009). *

• Braun J. Epidemiology and prognosis of ankylosing spondylitis. Radiologe 44: 209-210, 212-216 (2004).

• Bravo HC, Lee KE, Klein BE, Klein R, Iyengar SK, Wahba G. Examining the relative influence of familial, genetic, and environmental covariate information in flexible risk models. Proc. Natl. Acad. Sci. U.S.A. 106: 8128-8133 (2009). *

• Breitling LP, Raum E, Muller H, Rothenbacher D, Brenner H. Synergism between smoking and alcohol consumption with respect to serum gamma-glutamyltransferase. Hepatology 49: 802-808 (2009). *

• Brennan A, Bansback N, Nixon R, Madan J, Harrison M, Watson K, Symmons D. Modelling the cost effectiveness of TNF-alpha antagonists in the management of rheumatoid arthritis: results from the British Society for Rheumatology Biologics Registry. Rheumatology (Oxford) 46: 1345-1354 (2007). *

• Brenner AV, Butler MA, Wang SS, Ruder AM, Rothman N, Schulte PA, Chanock SJ, Fine HA, Linet MS, Inskip PD. Single nucleotide polymorphisms in selected cytokine genes and risk of adult glioma. Carcinogenesis 28: 2543-2547 (2007). *

• Brenner H, Chang-Claude J, Seiler CM, Sturmer T, Hoffmeister M. Case-control study supports extension of surveillance interval after colonoscopic polypectomy to at least 5 yr. Am. J. Gastroenterol. 102: 1739-1744 (2007). *

• Brenner H, Haug U, Arndt V, Stegmaier C, Altenhofen L, Hoffmeister M. Low risk of colorectal cancer and advanced adenomas more than 10 years after negative colonoscopy. Gastroenterology Nov 9 [Epub ahead of print] (2009). *

• Breunis WB, Tarazona-Santos E, Chen R, Kiley M, Rosenberg SA, Chanock SJ. Influence of cytotoxic T lymphocyte-associated antigen 4 (CTLA4) common polymorphisms on outcome in treatment of melanoma patients with CTLA-4 blockade. J. Immunother. 31: 586-590 (2008).

• Brewer GJ. Neurologically presenting Wilson's disease: epidemiology, pathophysiology and treatment. CNS Drugs 19: 185-192 (2005).

• Briggs FB, Ramsay PP, Madden E, Norris JM, Holers VM, Mikuls TR, Sokka T, Seldin MF, Gregersen PK, Criswell LA, Barcellos LF. Supervised machine learning and logistic regression identifies novel epistatic risk factors with PTPN22 for rheumatoid arthritis. Genes Immun. Jan 21 [Epub ahead of print] (2010).

• Brinker AD, Wassel RT, Lyndly J, Serrano J, Avigan M, Lee WM, Seeff LB. Telithromycin-associated hepatotoxicity: clinical spectrum and causality assessment of 42 cases. Hepatology 49: 250-257 (2009). *

• Brinton LA, Buckley LM, Dvorkina O, Lubin JH, Colton T, Murray MC, Hoover R. Risk of connective tissue disorders among breast implant patients. Am. J. Epidemiol. 160: 619-627 (2004). *

• Briskey EN, Pamies RJ. Colorectal cancer: update on recent advances and their impact on screening protocols. J. Natl. Med. Assoc. 92: 222-230 (2000).

• Bristeau-Leprince A, Mateo V, Lim A, Magerus-Chatinet A, Solary E, Fischer A, Rieux-Laucat F, Gougeon ML. Human TCR alpha/beta+ CD4-CD8- double-negative T cells in patients with autoimmune lymphoproliferative syndrome express restricted Vbeta TCR diversity and are clonally related to CD8+ T cells. J. Immunol. 181: 440-448 (2008). *

• Brix TH, Hansen PS, Knudsen GP, Kringen MK, Kyvik KO, Orstavik KH, Hegedus L. No link between X chromosome inactivation pattern and simple goiter in females: evidence from a twin study. Thyroid 19: 165-169 (2009).

• Bronson PG, Ramsay PP, Thomson G, Barcellos LF; Diabetes Genetics Consortium. Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes. Diabetes Obes. Metab. 11 Suppl. 1: 74-83 (2009). *

• Broome U, Bergquist A. Hepatocellular carcinoma, cholangiocarcinoma, colon and pancreas carcinoma in patients with primary sclerosing cholangitis. Epidemiology and risk factors. Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper’s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 89-90. October 15-16 (2003). *

• Brophy S, Hickey S, Menon A, Taylor G, Bradbury L, Hamersma J, Calin A. Concordance of disease severity among family members with ankylosing spondylitis? J. Rheumatol. 31: 1775-1778 (2004).

• Brophy S, Pavy S, Lewis P, Taylor G, Bradbury L, Robertson D, Lovell C, Calin A. Inflammatory eye, skin, and bowel disease in spondyloarthritis: genetic, phenotypic, and environmental factors. J. Rheumatol. 28: 2667-2673 (2001).

• Brophy S, Taylor G, Blake D, Calin A. The interrelationship between sex, susceptibility factors, and outcome in ankylosing spondylitis and its associated disorders including inflammatory bowel disease, psoriasis, and iritis. J. Rheumatol. 30: 2054-2058 (2003).

• Brown JM, Pfau JC, Pershouse MA, Holian A. Silica, apoptosis, and autoimmunity. J. Immunotoxicol. 1: 177-187 (2005).

• Brown LM. Helicobacter pylori: epidemiology and routes of transmission. Epidemiol. Rev. 22: 283-297 (2000). *

• Brown LM, Gridley G, Check D, Landgren O. Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders. Blood 111: 3388-3394 (2008). *

• Brown MA. Genomewide screens in ankylosing spondylitis. Adv. Exp. Med. Biol. 649: 148-158 (2009).

• Brown MG, Kirby S, Skedgel C, Fisk JD, Murray TJ, Bhan V, Sketris IS. How effective are disease-modifying drugs in delaying progression in relapsing-onset MS? Neurology 69: 1498-1507 (2007).

• Brown SL. Epidemiology of silicone-gel breast implants. Epidemiology 13: S34-S39 (2002).

• Brownlee JW, Turner RB. New developments in the epidemiology and clinical spectrum of rhinovirus infections. Curr. Opin. Pediatr. 20: 67-71 (2008).

• Bruix J. Hepatocellular carcinoma. Falk Symposium 137. XII FALK LIVER WEEK 2003 (Part II) In honour of Hans Popper’s 100th Birthday. Liver Diseases: Advances in Treatment and Prevention. Freiburg (Germany). p. 31-33. October 17 - 19 (2003). *

• Brunner E. Oily fish and omega 3 fat supplements. BMJ 332: 739-740 (2006). *

• Brunner EJ, Jones PJ, Friel S, Bartley M. Fish, human health and marine ecosystem health: policies in collision. Int. J. Epidemiol. 38: 93-100 (2009).

• Brunt EM, Tiniakos DG. Metabolic storage diseases: amyloidosis. Clin. Liver Dis. 8: 915-930, x (2004).

• Buchbinder R, March L, Lassere M, Briggs AM, Portek I, Reid C, Meehan A, Henderson L, Wengier L, van den Haak R. Effect of treatment with biological agents for arthritis in Australia: the Australian Rheumatology Association Database. Intern. Med. J. 37: 591-600 (2007).

• Bucuvalas J, Yazigi N, Squires Jr RH. Acute liver failure in children. Clin. Liver Dis. 10: 149-168 (2006).

• Budillon G. The epidemiology of cholestasis in hepatopathies. Ann. Ital. Med. Int. 8: 36S-40S (1993).

• Burg JR, Gist GL. The National Exposure Registry: procedures for establishing a registry of persons environmentally exposed to hazardous substances. Toxicol. Ind. Health 11: 231-248 (1995).

• Burke W, Thomson E, Khoury MJ, McDonnell SM, Press N, Adams PC, Barton JC, Beutler E, Brittenham G, Buchanan A, Clayton EW, Cogswell ME, Meslin EM, Motulsky AG, Powell LW, Sigal E, Wilfond BS, Collins FS. Hereditary hemochromatosis: gene discovery and its implications for population-based screening. JAMA 280: 172-178 (1998).

• Burnham JM, Shults J, Semeao E, Foster BJ, Zemel BS, Stallings VA, Leonard MB. Body-composition alterations consistent with cachexia in children and young adults with Crohn disease. Am. J. Clin. Nutr. 82: 413-420 (2005). *

• Burr ML, Dunstan FD, George CH. Is fish oil good or bad for heart disease? Two trials with apparently conflicting results. J. Membr. Biol. 206: 155-163 (2005). *

• Burwick RM, Ramsay PP, Haines JL, Hauser SL, Oksenberg JR, Pericak-Vance MA, Schmidt S, Compston A, Sawcer S, Cittadella R, Savettieri G, Quattrone A, Polman CH, Uitdehaag BM, Zwemmer JN, Hawkins CP, Ollier WE, Weatherby S, Enzinger C, Fazekas F, et al. APOE epsilon variation in multiple sclerosis susceptibility and disease severity: some answers. Neurology 66: 1373-1383 (2006).

• Byun E, Caillier SJ, Montalban X, Villoslada P, Fernandez O, Brassat D, Comabella M, Wang J, Barcellos LF, Baranzini SE, Oksenberg JR. Genome-wide pharmacogenomic analysis of the response to interferon beta therapy in multiple sclerosis. Arch. Neurol. 65: 337-344 (2008).

• Caballero Plasencia AM, Lopez Callejas C, Valenzuela Barranco M, Montero Garcia M, Muros Navarro MC, de los Reyes Garcia MC, Sanchez Martinez H, Bellot Garcia V. Epidemiology of primary biliary cirrhosis in the South area of Granada. Med. Clin. (Barc.) 96: 481-485 (1991).

• Caccio SM. Molecular epidemiology of human cryptosporidiosis. Parassitologia 47: 185-192 (2005).

• Cai S, Garcia Rodriguez LA, Masso-Gonzalez EL, Hernandez-Diaz S. Uncomplicated peptic ulcer in the UK: trends from 1997 - 2005. Aliment. Pharmacol. Ther. 30: 1039-1048 (2009). *

• Caire-Juvera G, Ritenbaugh C, Wactawski-Wende J, Snetselaar LG, Chen Z. Vitamin A and retinol intakes and the risk of fractures among participants of the Women's Health Initiative Observational Study. Am. J. Clin. Nutr. 89: 323-330 (2009). *

• Calamia KT, Wilson FC, Icen M, Crowson CS, Gabriel SE, Kremers HM. Epidemiology and clinical characteristics of Behcet's disease in the US: a population-based study. Arthritis Rheum. 61: 600-604 (2009). *

• Calis JC, Phiri KS, Faragher EB, Brabin BJ, Bates I, Cuevas LE, de Haan RJ, Phiri AI, Malange P, Khoka M, Hulshof PJ, van Lieshout L, Beld MG, Teo YY, Rockett KA, Richardson A, Kwiatkowski DP, Molyneux ME, van Hensbroek MB. Severe anemia in Malawian children. N. Engl. J. Med. 358: 888-899 (2008). *

• Calkins BM. A meta-analysis of the role of smoking in inflammatory bowel disease. Dig. Dis. Sci. 34: 1841-1854 (1989).

• Cama VA, Ross JM, Crawford S, Kawai V, Chavez-Valdez R, Vargas D, Vivar A, Ticona E, Navincopa M, Williamson J, Ortega Y, Gilman RH, Bern C, Xiao L. Differences in clinical manifestations among Cryptosporidium species and subtypes in HIV-infected persons. J. Infect. Dis. 196: 684-691 (2007). *

• Camilla R, Magnetti F, Barbera C, Bignamini E, Riggi C, Coppo R; on behalf of the core group of the Children with Chronic Organ disease Network. Children with chronic organ failure possibly ending in organ transplantation: a survey in an Italian region of 5,000,000 inhabitants. Acta Paediatr. 97: 1285-1291 (2008). *

• Camilleri M. Is there an experimental basis for the development of ischaemic colitis as a result of 5-HT(3) antagonist treatment? Neurogastroenterol. Motil. 19: 77-84 (2007). *

• Camilleri M. GIH clinical research 2003-2004: the year in review. Clin. Gastroenterol. Hepatol. 2: 1043-1047 (2004). *

• Campana S, Taccetti G, Ravenni N, Favari F, Cariani L, Sciacca A, Savoia D, Collura A, Fiscarelli E, De Intinis G, Busetti M, Cipolloni A, d'Aprile A, Provenzano E, Collebrusco I, Frontini P, Stassi G, Trancassini M, Tovagliari D, et al. Transmission of Burkholderia cepacia complex: evidence for new epidemic clones infecting cystic fibrosis patients in Italy. J. Clin. Microbiol. 43: 5136-5142 (2005). *

• Campo DS, Dimitrova Z, Mitchell RJ, Lara J, Khudyakov Y. Coordinated evolution of the hepatitis C virus. Proc. Natl. Acad. Sci. U.S.A. 105: 9685-9690 (2008). *

• Canales RP, Araya QM, Alliende GF, Hunter MB, Alarcon OT, Chavez SE. Diagnosis and clinical presentations of celiac disease: a multicenter study. Rev. Med. Chil. 136: 296-303 (2008).

• Cao W, Cai L, Rao JY, Pantuck A, Lu ML, Dalbagni G, Reuter V, Scher H, Cordon-Cardo C, Figlin RA, Belldegrun A, Zhang ZF. Tobacco smoking, GSTP1 polymorphism, and bladder carcinoma. Cancer 104: 2400-2408 (2005). *

• Capocaccia R, Sant M, Berrino F, Simonetti A, Santi V, Trevisani F; the EUROCARE Working Group. Hepatocellular carcinoma: trends of incidence and survival in Europe and the United States at the end of the 20th century. Am. J. Gastroenterol. 102: 1661-1670 (2007). *

• Caporaso N, Gu F, Chatterjee N, Sheng-Chih J, Yu K, Yeager M, Chen C, Jacobs K, Wheeler W, Landi MT, Ziegler RG, Hunter DJ, Chanock S, Hankinson S, Kraft P, Bergen AW. Genome-wide and candidate gene association study of cigarette smoking behaviors. PLoS ONE 4: e4653 (2009). *

• Caporaso NE, Goldin LR, Anderson WF, Landgren O. Current insight on trends, causes, and mechanisms of Hodgkin's lymphoma. Cancer J. 15: 117-123 (2009).

• Card T, Hubbard R, Logan RF. Mortality in inflammatory bowel disease: a population-based cohort study. Gastroenterology 125: 1583-1590 (2003). *

• Card T, Logan RF, Rodrigues LC, Wheeler JG. Antibiotic use and the development of Crohn's disease. Gut 53: 246-250 (2004). *

• Card T, West J, Hubbard R, Logan RF. Hip fractures in patients with inflammatory bowel disease and their relationship to corticosteroid use: a population based cohort study. Gut 53: 251-255 (2004). *

• Card TR, Solaymani-Dodaran M, Hubbard R, Logan RF, West J. Is an internal comparison better than using national data when estimating mortality in longitudinal studies? J. Epidemiol. Community Health 60: 819-821 (2006).

• Card TR, Solaymani-Dodaran M, West J. Incidence and mortality of primary sclerosing cholangitis in the UK: a population-based cohort study. J. Hepatol. 48: 939-944 (2008).

• Cardenas VM, Mulla ZD, Ortiz M, Graham DY. Iron deficiency and Helicobacter pylori infection in the United States. Am. J. Epidemiol. 163: 127-134 (2006). *

• Carpenter EL, Mick R, Rech AJ, Beatty GL, Colligon TA, Rosenfeld MR, Kaplan DE, Chang KM, Domchek SM, Kanetsky PA, Fecher LA, Flaherty KT, Schuchter LM, Vonderheide RH. Collapse of the CD27+ B-cell compartment associated with systemic plasmacytosis in patients with advanced melanoma and other cancers. Clin. Cancer Res. 15: 4277-4287 (2009).

• Carson KR, Focosi D, Major EO, Petrini M, Richey EA, West DP, Bennett CL. Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a review from the Research on Adverse Drug Events and Reports (RADAR) Project. Lancet Oncol. 10: 816-824 (2009).

• Carter KW, Pluzhnikov A, Timms AE, Miceli-Richard C, Bourgain C, Wordsworth BP, Jean-Pierre H, Cox NJ, Palmer LJ, Breban M, Reveille JD, Brown MA. Combined analysis of three whole genome linkage scans for ankylosing spondylitis. Rheumatology (Oxford) 46: 763-771 (2007). *

• Carter RE, Lipsitz SR, Tilley BC. Quasi-likelihood estimation for relative risk regression models. Biostatistics 6: 39-44 (2005).

• Carthy D, Ollier W, Papasteriades C, Pappas H, Thomson W. A shared HLA-DRB1 sequence confers RA susceptibility in Greeks. Eur. J. Immunogenet. 20: 391-398 (1993).

• Cartier KC, Miscimarra L, Dazard JE, Song Y, Iyengar SK, Rao JS. Studying genetic determinants of natural variation in human gene expression using Bayesian ANOVA. BMC Proc. 1 Suppl. 1: S115 (2007). *

• Carty CL, Heagerty P, Heckbert SR, Enquobahrie DA, Jarvik GP, Davis S, Tracy RP, Reiner AP. Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the cardiovascular health study. J. Atheroscler. Thromb. 16: 419-430 (2009).

• Casais P, Alberto MF, Salviu MJ, Meschengieser SS, Aixala M, Lazzari MA. Pilot study of homocysteine and cysteine in patients with thrombosis in different vascular sites. Epidemiology and response to folate. Thromb. Res. 123: 592-596 (2009). *

• Casas JP, Cavalleri GL, Bautista LE, Smeeth L, Humphries S, Hingorani AD. Endothelial nitric oxide synthase gene polymorphisms and cardiovascular disease: a HuGE review. Am. J. Epidemiol. 164: 921-935 (2006). *

• Casellas F, Lopez Vivancos J, Malagelada JR. Current epidemiology and accessibility to diet compliance in adult celiac disease. Rev. Esp. Enferm. Dig. 98: 408-419 (2006).

• Castaldo G, Polizzi A, Tomaiuolo R, Cazeneuve C, Girodon E, Santostasi T, Salvatore D, Raia V, Rigillo N, Goossens M, Salvatore F. Comprehensive cystic fibrosis mutation epidemiology and haplotype characterization in a southern Italian population. Ann. Hum. Genet. 69: 15-24 (2005). *

• Castiblanco J, Anaya JM. The nature and nurture of common autoimmunity. Ann. N. Y. Acad. Sci. 1109: 1-8 (2007). *

• Castro FA, Haimila K, Sareneva I, Schmitt M, Lorenzo J, Kunkel N, Kumar R, Forsti A, Kjellberg L, Hallmans G, Lehtinen M, Hemminki K, Pawlita M. Association of HLA-DRB1, interleukin-6 and cyclin D1 polymorphisms with cervical cancer in the Swedish population - a candidate gene approach. Int. J. Cancer 125: 1851-1858 (2009). *

• Catassi C, Cobellis G. Coeliac disease epidemiology is alive and kicking, especially in the developing world. Dig. Liver Dis. 39: 908-910 (2007).

• Cawood AL, Carroll MP, Wootton SA, Calder PC. Is there a case for n-3 fatty acid supplementation in cystic fibrosis? Curr. Opin. Clin. Nutr. Metab. Care 8: 153-159 (2005).

• Centers for Disease Control and Prevention (CDC). Severe Clostridium difficile-associated disease in populations previously at low risk - four states, 2005. MMWR Morb. Mortal. Wkly. Rep. 54: 1201-1205 (2005). *

• Centritto F, Iacoviello L, di Giuseppe R, De Curtis A, Costanzo S, Zito F, Grioni S, Sieri S, Donati MB, de Gaetano G, Di Castelnuovo A; on behalf of Moli-sani Investigators. Dietary patterns, cardiovascular risk factors and C-reactive protein in a healthy Italian population. Nutr. Metab. Cardiovasc. Dis. 19: 697-706 (2009).

• Cerhan JR, Liu-Mares W, Fredericksen ZS, Novak AJ, Cunningham JM, Kay NE, Dogan A, Liebow M, Wang AH, Call TG, Habermann TM, Ansell SM, Slager SL. Genetic variation in tumor necrosis factor and the nuclear factor-kappaB canonical pathway and risk of non-Hodgkin's lymphoma. Cancer Epidemiol. Biomarkers Prev. 17: 3161-3169 (2008). *

• Cerhan JR, Novak AJ, Fredericksen ZS, Wang AH, Liebow M, Call TG, Dogan A, Witzig TE, Ansell SM, Habermann TM, Kay NE, Slager SL. Risk of non-Hodgkin lymphoma in association with germline variation in complement genes. Br. J. Haematol. 145: 614-623 (2009). *

• Cervera R, Boffa MC, Khamashta M, Hughes G. The Euro-Phospholipid project: epidemiology of the antiphospholipid syndrome in Europe. Lupus 18: 889-893 (2009). *

• Cervera R, Khamashta M, Hughes G. The Euro-lupus project: epidemiology of systemic lupus erythematosus in Europe. Lupus 18: 869-874 (2009). *

• Chabchoub G, Mnif M, Maalej A, Charfi N, Ayadi H, Abid M. Epidemiologic study of autoimmune thyroid disease in south Tunisia. Ann. Endocrinol. (Paris) 67: 591-595 (2006).

• Chambers JC, Zhang W, Li Y, Sehmi J, Wass MN, Zabaneh D, Hoggart C, Bayele H, McCarthy MI, Peltonen L, Freimer NB, Srai SK, Maxwell PH, Sternberg MJ, Ruokonen A, Abecasis G, Jarvelin MR, Scott J, Elliott P, Kooner JS. Genome-wide association study identifies variants in TMPRSS6 associated with hemoglobin levels. Nat. Genet. 41: 1170-1172 (2009). *

• Chambers JC, Zhao J, Terracciano CM, Bezzina CR, Zhang W, Kaba R, Navaratnarajah M, Lotlikar A, Sehmi JS, Kooner MK, Deng G, Siedlecka U, Parasramka S, El-Hamamsy I, Wass MN, Dekker LR, de Jong JS, Sternberg MJ, McKenna W, Severs NJ, de Silva R, et al. Genetic variation in SCN10A influences cardiac conduction. Nat. Genet. Jan 10 [Epub ahead of print] (2010). *

• Chamnan P, Shine BS, Haworth CS, Bilton D, Adler AI. Diabetes as a determinant of mortality in cystic fibrosis. Diabetes Care Nov 16 [Epub ahead of print] (2009).

• Chamulitrat W, Burhenne J, Rehlen T, Pathil A, Stremmel W. Bile salt-phospholipid conjugate ursodeoxycholyl lysophosphatidylethanolamide as a hepatoprotective agent. Hepatology 50: 143-154 (2009). *

• Chan KH, Song Y, Hsu YH, You NC, F Tinker L, Liu S. Common genetic variants in fatty acid-binding protein-4 (FABP4) and clinical diabetes risk in the Women's Health Initiative Observational Study. Obesity (Silver Spring) Jan 28 [Epub ahead of print] (2010). *

• Chandran V. Epidemiology of psoriatic arthritis. J. Rheumatol. 36: 213-215 (2009).

• Chandran V, Raychaudhuri SP. Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. J. Autoimmun. Dec 22 [Epub ahead of print] (2009).

• Chang AB, Bilton D. Exacerbations in cystic fibrosis: 4 - Non-cystic fibrosis bronchiectasis. Thorax 63: 269-276 (2008).

• Chang JH, McCluskey PJ, Wakefield D. Acute anterior uveitis and HLA-B27. Surv. Ophthalmol. 50: 364-388 (2005). *

• Chang JL, Bigler J, Schwarz Y, Li SS, Li L, King IB, Potter JD, Lampe JW. UGT1A1 polymorphism is associated with serum bilirubin concentrations in a randomized, controlled, fruit and vegetable feeding trial. J. Nutr. 137: 890-897 (2007). *

• Chang JS, Wiemels JL, Buffler PA. Allergies and childhood leukemia. Blood Cells Mol. Dis. 42: 99-104 (2009).

• Chang L, Chey WD, Harris L, Olden K, Surawicz C, Schoenfeld P. Incidence of ischemic colitis and serious complications of constipation among patients using alosetron: systematic review of clinical trials and post-marketing surveillance data. Am. J. Gastroenterol. 101: 1069-1079 (2006). *

• Chang SC, Rashid A, Gao YT, Andreotti G, Shen MC, Wang BS, Han TQ, Zhang BH, Sakoda LC, Leitzmann MF, Chen BE, Rosenberg P, Chen J, Chanock S, Hsing AW. Polymorphism of genes related to insulin sensitivity and the risk of biliary tract cancer and biliary stone: a population-based case-control study in Shanghai, China. Carcinogenesis 29: 944-948 (2008). *

• Chang WW, Su H, He L, Zhao KF, Wu JL, Xu ZW. Association between transforming growth factor-beta1 T869C polymorphism and rheumatoid arthritis: a meta-analysis. Rheumatology (Oxford) Jan 4 [Epub ahead of print] (2010).

• Chanock S. High marks for GWAS. Nat. Genet. 41: 765-766 (2009). *

• Chao C, Zhang ZF, Berthiller J, Boffetta P, Hashibe M. NAD(P)H:quinone oxidoreductase 1 (NQO1) Pro187Ser polymorphism and the risk of lung, bladder, and colorectal cancers: a meta-analysis. Cancer Epidemiol. Biomarkers Prev. 15: 979-987 (2006). *

• Chapelon-Abric C. Epidemiology of sarcoidosis and its genetic and environmental risk factors. Rev. Med. Interne. 25: 494-500 (2004).

• Chapman JM, Onnie CM, Prescott NJ, Fisher SA, Mansfield JC, Mathew CG, Lewis CM, Verzilli CJ, Whittaker JC. Searching for genotype-phenotype structure: using hierarchical log-linear models in Crohn disease. Am. J. Hum. Genet. 84: 178-187 (2009). *

• Charli-Joseph Y, Cruz-Fuentes C, Orozco-Topete R. Incidence of adverse cutaneous drug reactions in a Mexican sample: an exploratory study on their association to tumour necrosis factor alpha TNF2 allele. J. Eur. Acad. Dermatol. Venereol. 23: 788-792 (2009). *

• Chatterjee A, Bosch RJ, Hunter DJ, Manji K, Msamanga GI, Fawzi WW. Vitamin A and vitamin B-12 concentrations in relation to mortality and morbidity among children born to HIV-infected women. J. Trop. Pediatr. Jun 5 [Epub ahead of print] (2009).

• Chen AB, D'Amico AV, Neville BA, Earle CC. Patient and treatment factors associated with complications after prostate brachytherapy. J. Clin. Oncol. 24: 5298-5304 (2006). *

• Chen J, Amos CI, Merriman KW, Wei Q, Sen S, Killary AM, Frazier ML. Genetic variants of p21 and p27 and pancreatic cancer risk in non-Hispanic whites: a case-control study. Pancreas 39: 1-4 (2010).

• Chen J, Giovannucci E, Kelsey K, Rimm EB, Stampfer MJ, Colditz GA, Spiegelman D, Willett WC, Hunter DJ. A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer. Cancer Res. 56: 4862-4864 (1996). *

• Chen J, Giovannucci EL, Hunter DJ. MTHFR polymorphism, methyl-replete diets and the risk of colorectal carcinoma and adenoma among U.S. men and women: an example of gene-environment interactions in colorectal tumorigenesis. J. Nutr. 129: 560S-564S (1999). *

• Chen J, Killary AM, Sen S, Amos CI, Evans DB, Abbruzzese JL, Frazier ML. Polymorphisms of p21 and p27 jointly contribute to an earlier age at diagnosis of pancreatic cancer. Cancer Lett. 272: 32-39 (2008).

• Chen JD, Yang HI, Iloeje UH, You SL, Lu SN, Wang LY, Su J, Sun CA, Liaw YF, Chen CJ; for the Risk Evaluation of Viral Load Elevation and Associated Liver Disease/Cancer in HBV (the REVEAL-HBV) Study Group. Carriers of inactive hepatitis B virus are still at risk for hepatocellular carcinoma and liver-related death. Gastroenterology Jan 26 [Epub ahead of print] (2010).

• Chen L, Davey Smith G, Evans DM, Cox A, Lawlor DA, Donovan J, Yuan W, Day IN, Martin RM, Lane A, Rodriguez S, Davis M, Zuccolo L, Collin SM, Hamdy F, Neal D, Lewis SJ. Genetic variants in the vitamin D receptor are associated with advanced prostate cancer at diagnosis: findings from the prostate testing for cancer and treatment study and a systematic review. Cancer Epidemiol. Biomarkers Prev. 18: 2874-2881 (2009).

• Chen RT, Pless R, Destefano F. Epidemiology of autoimmune reactions induced by vaccination. J. Autoimmun. 16: 309-318 (2001).

• Chen WV, Amos CI, Etzel CJ, Shete S, Gregersen PK. Comparison of genome-wide single-nucleotide polymorphism linkage analyses in Caucasian and Hispanic NARAC families. BMC Proc. 1 Suppl. 1: S97 (2007). *

• Chen X, Liu CT, Zhang M, Zhang H. A forest-based approach to identifying gene and gene gene interactions. Proc. Natl. Acad. Sci. U.S.A. 104: 19199-19203 (2007). *

• Chen YF, Jobanputra P, Barton P, Jowett S, Bryan S, Clark W, Fry-Smith A, Burls A. A systematic review of the effectiveness of adalimumab, etanercept and infliximab for the treatment of rheumatoid arthritis in adults and an economic evaluation of their cost-effectiveness. Health Technol. Assess. 10: 1-248 (2006). *

• Cheong HS, Kim LH, Park BL, Choi YH, Park HS, Hong SJ, Choi BW, Park CS, Shin HD. Association analysis of interleukin 5 receptor alpha subunit (IL5RA) polymorphisms and asthma. J. Hum. Genet. 50: 628-634 (2005). *

• Cheong HS, Lee SO, Choi CB, Sung YK, Shin HD, Bae SC. MERTK polymorphisms associated with risk of haematological disorders among Korean SLE patients. Rheumatology (Oxford) 46: 209-214 (2007). *

• Chhagan MK, Van den Broeck J, Luabeya KK, Mpontshane N, Tucker KL, Bennish ML. Effect of micronutrient supplementation on diarrhoeal disease among stunted children in rural South Africa. Eur. J. Clin. Nutr. 63: 850-857 (2009). *

• Chiodini RJ. Crohn's disease and the mycobacterioses: a review and comparison of two disease entities. Clin. Microbiol. Rev. 2: 90-117 (1989). *

• Chitkara DK, Rawat DJ, Talley NJ. The epidemiology of childhood recurrent abdominal pain in Western countries: a systematic review. Am. J. Gastroenterol. 100: 1868-1875 (2005). *

• Chiu WA, Caldwell JC, Keshava N, Scott CS. Key scientific issues in the health risk assessment of trichloroethylene. Environ. Health Perspect. 114: 1445-1449 (2006). *

• Cho J. Update on inflammatory bowel disease genetics. Curr. Gastroenterol. Rep. 2: 434-439 (2000).

• Cho JH. Update on the genetics of inflammatory bowel disease. Curr. Gastroenterol. Rep. 3: 458-463 (2001).

• Christian JB, Lapane KL, Hume AL, Eaton CB, Weinstock MA. Association of ACE inhibitors and angiotensin receptor blockers with keratinocyte cancer prevention in the randomized VATTC trial. J. Natl. Cancer Inst. 100: 1223-1232 (2008). *

• Christiani DC, Mehta AJ, Yu CL. Genetic susceptibility to occupational exposures. Occup. Environ. Med. 65: 430-436 (2008).

• Chung CC, Magalhaes W, Gonzalez-Bosquet J, Chanock SJ. Genome-wide association studies in cancer - current and future directions. Carcinogenesis Nov 11 [Epub ahead of print] (2009). *

• Chung H, Nettleton JA, Lemaitre RN, Barr RG, Tsai MY, Tracy RP, Siscovick DS. Frequency and type of seafood consumed influence plasma (n-3) fatty acid concentrations. J. Nutr. 138: 2422-2427 (2008). *

• Church LD, Churchman SM, Hawkins PN, McDermott MF. Hereditary auto-inflammatory disorders and biologics. Springer Semin. Immunopathol. 27: 494-508 (2006). *

• Ciccolallo L, Capocaccia R, Coleman MP, Berrino F, Coebergh JW, Damhuis RA, Faivre J, Martinez-Garcia C, Moller H, Ponz de Leon M, Launoy G, Raverdy N, Williams EM, Gatta G. Survival differences between European and US patients with colorectal cancer: role of stage at diagnosis and surgery. Gut 54: 268-273 (2005). *

• Cicek MS, Liu X, Schumacher FR, Casey G, Witte JS. Vitamin D receptor genotypes/haplotypes and prostate cancer risk. Cancer Epidemiol. Biomarkers Prev. 15: 2549-2552 (2006). *

• Cimmino MA. Epidemiology of psoriasis and psoriatic arthritis. Reumatismo 59 Suppl. 1: 19-24 (2007). *

• Claessen H, Brenner H, Drath C, Arndt V. Gamma-glutamyltransferase and disability pension: a cohort study of construction workers in Germany. Hepatology 51: 482-490 (2010).

• Clark-Curtiss JE, Haydel SE. Molecular genetics of Mycobacterium tuberculosis pathogenesis. Annu. Rev. Microbiol. 57: 517-549 (2003). *

• Clarke AE, Ramsey-Goldman R, Bernatsky S. Revisiting the issue of malignancy risk in systemic lupus erythematosus. Curr. Rheumatol. Rep. 7: 476-481 (2005).

• Clarke L, Moore JE, Millar BC, Crowe M, Xu J, Goldsmith CE, Murphy RG, Dooley JS, Rendall J, Elborn JS. Molecular epidemiology of Pseudomonas aeruginosa in adult patients with cystic fibrosis in Northern Ireland. Br. J. Biomed. Sci. 65: 18-21 (2008).

• Clementi M, Gianantonio ED. Genetic susceptibility to infectious diseases. Reprod. Toxicol. 21: 345-349 (2006).

• Coggins RP, Cawkwell L, Bell SM, Crockford GP, Quirke P, Finan PJ, Bishop DT. Association between family history and mismatch repair in colorectal cancer. Gut 54: 636-642 (2005). *

• Cohen MB. Clostridium difficile infections: emerging epidemiology and new treatments. J. Pediatr. Gastroenterol. Nutr. 48 Suppl. 2: S63-S65 (2009). *

• Cohen SM, Ahn J. Review article: the diagnosis and management of alcoholic hepatitis. Aliment. Pharmacol. Ther. 30: 3-13 (2009). *

• Colbert RA, Deodhar AA, Fox D, Gravallese EM, Khan MA, McGonagle D, Reveille JD, Schett G, Weisman M, Clegg DO; for the SPARTAN Group. Entheses and bones in spondyloarthritis: 2008 Annual Research and Education Meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN). J. Rheumatol. 36: 1527-1531 (2009).

• Colbert RA, Deodhar AA, Khan MA, Lories RJ, Maksymowych WP, Reveille JD, Ritchlin CT, Rosenbaum JT, Targan SR, Weisman M, Clegg DO. 2007 Annual Research and Education Meeting of the Spondyloarthritis Research and Therapy Network (SPARTAN). J. Rheumatol. 35: 1398-1402 (2008).

• Coleman H, Chew E. Nutritional supplementation in age-related macular degeneration. Curr. Opin. Ophthalmol. 18: 220-223 (2007).

• Coletta DK, Schneider J, Hu SL, Dyer TD, Puppala S, Farook VS, Arya R, Lehman DM, Blangero J, Defronzo RA, Duggirala R, Jenkinson CP. Genomewide linkage scan for genes influencing plasma triglyceride levels in the Veterans Administration Genetic Epidemiology Study (VAGES). Diabetes 58: 279-284 (2009). *

• Colli A, Fraquelli M, Casazza G, Massironi S, Colucci A, Conte D, Duca P. Accuracy of ultrasonography, spiral CT, magnetic resonance, and alpha-fetoprotein in diagnosing hepatocellular carcinoma: a systematic review. Am. J. Gastroenterol. 101: 513-523 (2006). *

• Collie A. Cognition in liver disease. Liver Int. 25: 1-8 (2005). *

• Colombel JF, Vernier-Massouille G, Cortot A, Gower-Rousseau C, Salomez JL. Epidemiology and risk factors of inflammatory bowel diseases. Bull. Acad. Natl. Med. 191: 1105-1118 (2007).

• Colombel JF, Watson AJ, Neurath MF. The 10 remaining mysteries of inflammatory bowel disease. Gut 57: 429-433 (2008). *

• Comstock CE, Augello MA, Benito RP, Karch J, Tran TH, Utama FE, Tindall EA, Wang Y, Burd CJ, Groh EM, Hoang HN, Giles GG, Severi G, Hayes VM, Henderson BE, Le Marchand L, Kolonel LN, Haiman CA, Baffa R, Gomella LG, Knudsen ES, Rui H, Henshall SM, et al. Cyclin D1 splice variants: polymorphism, risk, and isoform-specific regulation in prostate cancer. Clin. Cancer Res. 15: 5338-5349 (2009). *

• Confavreux C, Vukusic S. Accumulation of irreversible disability in multiple sclerosis: from epidemiology to treatment. Clin. Neurol. Neurosurg. 108: 327-332 (2006).

• Conway P, Currie CJ. Descriptive epidemiology of hospitalisation for psoriasis. Curr. Med. Res. Opin. 24: 3487-3491 (2008).

• Coogan PF, Rosenberg L. The use of folic acid antagonists and the risk of colorectal cancer. Pharmacoepidemiol. Drug Saf. 16: 1111-1119 (2007).

• Cooley P, Taylor KH, Czika W, Seifer C, Taylor JF. Analysis of a biomarker for Wegener's granulomatosis. Int. J. Immunogenet. 32: 237-243 (2005). *

• Cooper GS, Bynum ML, Somers EC. Recent insights in the epidemiology of autoimmune diseases: improved prevalence estimates and understanding of clustering of diseases. J. Autoimmun. 33: 197-207 (2009).

• Cooper GS, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS. Risk factors for development of systemic lupus erythematosus: allergies, infections, and family history. J. Clin. Epidemiol. 55: 982-989 (2002).

• Cooper GS, Koroukian SM. Geographic variation among medicare beneficiaries in the use of colorectal carcinoma screening procedures. Am. J. Gastroenterol. 99: 1544-1550 (2004). *

• Cooper GS, Miller FW, Pandey JP. The role of genetic factors in autoimmune disease: implications for environmental research. Environ. Health Perspect. 107 Suppl. 5: 693-700 (1999).

• Cooper GS, Parks CG. Occupational and environmental exposures as risk factors for systemic lupus erythematosus. Curr. Rheumatol. Rep. 6: 367-374 (2004).

• Cooper GS, Wither J, McKenzie T, Claudio JO, Bernatsky S, Fortin PR. The prevalence and accuracy of self-reported history of 11 autoimmune diseases. J. Rheumatol. 35: 2001-2004 (2008).

• Coppus AM, Fekkes D, Verhoeven WM, Evenhuis HM, van Duijn CM. Neopterin and the risk of dementia in persons with Down syndrome. Neurosci. Lett. 458: 60-64 (2009).

• Corella D, Ordovas JM. Single nucleotide polymorphisms that influence lipid metabolism: interaction with dietary factors. Annu. Rev. Nutr. 25: 341-390 (2005). *

• Cornelis MC, Qi L, Kraft P, Hu FB. TCF7L2, dietary carbohydrate, and risk of type 2 diabetes in US women. Am. J. Clin. Nutr. 89: 1256-1262 (2009). *

• Coronel-Perez IM, Rodríguez-Rey EM, Perez-Bernal AM, Camacho FM. Epidemiology of pemphigus in Hospital Universitario Virgen Macarena, Seville, Spain, 2005-2006. Actas Dermosifiliogr. 100: 121-125 (2009).

• Corrao G, Zambon A, Bagnardi V, D'Amicis A, Klatsky A; Collaborative SIDECIR Group. Coffee, caffeine, and the risk of liver cirrhosis. Ann. Epidemiol. 11: 458-465 (2001).

• Cosmetic Ingredient Review Expert Panel. Final safety assessment of coal tar as used in cosmetics. Int. J. Toxicol. 27 Suppl. 2: 1-24 (2008).

• Costacou T, Ferrell RE, Ellis D, Orchard TJ. Haptoglobin genotype and renal function decline in type 1 diabetes. Diabetes 58: 2904-2909 (2009).

• Costacou T, Ferrell RE, Orchard TJ. Haptoglobin genotype: a determinant of cardiovascular complication risk in type 1 diabetes. Diabetes 57: 1702-1706 (2008). *

• Costenbader KH, Karlson EW. Cigarette smoking and autoimmune disease: what can we learn from epidemiology? Lupus 15: 737-745 (2006). *

• Costner MI, Grau RH. Update on connective tissue diseases in dermatology. Semin. Cutan. Med. Surg. 25: 207-220 (2006).

• Cotch MF, Hoffman GS, Yerg DE, Kaufman GI, Targonski P, Kaslow RA. The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources. Arthritis Rheum. 39: 87-92 (1996).

• Cottone M, Cipolla C, Rosselli M. Epidemiology and pathogenesis of Crohn's disease. Chir. Ital. 47: 1-7 (1995).

• Cottone M, Martorana G, Di Mitri R, Camma C, Caprilli R. Epidemiology of inflammatory bowel disease in Italy. Ital. J. Gastroenterol. Hepatol. 31: 503-507 (1999).

• Coutinho A, Caramalho I, Seixas E, Demengeot J. Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection. Curr. Top. Microbiol. Immunol. 293: 43-71 (2005).

• Cowen JB, Sjostrom BF, Doughty AS, Schiffer RB. Case-finding for MS prevalence studies in small communities requires a community-based approach. Neuroepidemiology 28: 246-252 (2007).

• Cozzolongo R, Osella AR, Elba S, Petruzzi J, Buongiorno G, Giannuzzi V, Leone G, Bonfiglio C, Lanzilotta E, Manghisi OG, Leandro G. Epidemiology of HCV infection in the general population: a survey in a Southern Italian town. Am. J. Gastroenterol. 104: 2740-2746 (2009). *

• Crane SJ, Locke GR, Harmsen WS, Diehl NN, Zinsmeister AR, Melton LJ, Romero Y, Talley NJ. Subsite-specific risk factors for esophageal and gastric adenocarcinoma. Am. J. Gastroenterol. 102: 1596-1602 (2007). *

• Cremonini F, Talley NJ. Irritable bowel syndrome: epidemiology, natural history, health care seeking and emerging risk factors. Gastroenterol. Clin. North Am. 34: 189-204 (2005).

• Criscione VD, Weinstock MA, Naylor MF, Luque C, Eide MJ, Bingham SF; for the Department of Veteran Affairs Topical Tretinoin Chemoprevention Trial Group. Actinic keratoses: natural history and risk of malignant transformation in the Veterans Affairs Topical Tretinoin Chemoprevention Trial. Cancer 115: 2523-2530 (2009).

• Crosdale DJ, Ollier WE, Thomson W, Dyer PA, Jensenious J, Johnson RW, Poulton KV. Mannose binding lectin (MBL) genotype distributions with relation to serum levels in UK Caucasoids. Eur. J. Immunogenet. 27: 111-117 (2000). *

• Crosdale DJ, Poulton KV, Ollier WE, Thomson W, Denning DW. Mannose-binding lectin gene polymorphisms as a susceptibility factor for chronic necrotizing pulmonary aspergillosis. J. Infect. Dis. 184: 653-656 (2001). *

• Cross RK, Arora M, Finkelstein J. Acceptance of telemanagement is high in patients with inflammatory bowel disease. J. Clin. Gastroenterol. 40: 200-208 (2006).

• Cross RK, Jung C, Wasan S, Joshi G, Sawyer R, Roghmann MC. Racial differences in disease phenotypes in patients with Crohn's disease. Inflamm. Bowel Dis. 12: 192-198 (2006). *

• Cross RK, Lapshin O, Finkelstein J. Patient subjective assessment of drug side effects in inflammatory bowel disease. J. Clin. Gastroenterol. 42: 244-251 (2008).

• Crowe FL, Allen NE, Appleby PN, Overvad K, Aardestrup IV, Johnsen NF, Tjonneland A, Linseisen J, Kaaks R, Boeing H, Kroger J, Trichopoulou A, Zavitsanou A, Trichopoulos D, Sacerdote C, Palli D, Tumino R, Agnoli C, Kiemeney LA, Bueno-de-Mesquita HB, et al. Fatty acid composition of plasma phospholipids and risk of prostate cancer in a case-control analysis nested within the European Prospective Investigation into Cancer and Nutrition. Am. J. Clin. Nutr. 88: 1353-1363 (2008). *

• Cui Y, Rohan TE. Vitamin D, calcium, and breast cancer risk: a review. Cancer Epidemiol. Biomarkers Prev. 15: 1427-1437 (2006). *

• Curtin K, Iles MM, Camp NJ. Identifying rarer genetic variants for common complex diseases: diseased versus neutral discovery panels. Ann. Hum. Genet. 73: 54-60 (2009). *

• Curtin K, Wong J, Allen-Brady K, Camp NJ. Meta-genetic association of rheumatoid arthritis and PTPN22 using PedGenie 2.1. BMC Proc. 1 Suppl. 1: S12 (2007). *

• Czaja AJ. Autoimmune hepatitis - approach to diagnosis. MedGenMed. 8: 55 (2006). *

• Czaja AJ. Autoimmune liver disease. Curr. Opin. Gastroenterol. 20: 231-240 (2004).

• Czerniecki BJ, Koski GK, Koldovsky U, Xu S, Cohen PA, Mick R, Nisenbaum H, Pasha T, Xu M, Fox KR, Weinstein S, Orel SG, Vonderheide R, Coukos G, Demichele A, Araujo L, Spitz FR, Rosen M, Levine BL, June C, Zhang PJ. Targeting HER-2/neu in early breast cancer development using dendritic cells with staged interleukin-12 burst secretion. Cancer Res. 67: 1842-1852 (2007). *

• D'Archivio M, Silano M, Fagnani C, Scazzocchio B, Nistico L, Giovannini C, Vari' R, D'Ippolito C, Cotichini R, Stazi MA, De Vincenzi M. Clinical evolution of celiac disease in Italy 1982-2002. J. Clin. Gastroenterol. 38: 877-879 (2004).

• D'Cruz DP, Khamashta MA, Hughes GR. Systemic lupus erythematosus. Lancet 369: 587-596 (2007). *

• Dababneh A, Gonzalez-Gay MA, Garcia-Porrua C, Hajeer A, Thomson W, Ollier W. Giant cell arteritis and polymyalgia rheumatica can be differentiated by distinct patterns of HLA class II association. J. Rheumatol. 25: 2140-2145 (1998).

• Dahlman I, Nilsson M, Jiao H, Hoffstedt J, Lindgren CM, Humphreys K, Kere J, Gustafsson JA, Arner P, Dahlman-Wright K. Liver X receptor gene polymorphisms and adipose tissue expression levels in obesity. Pharmacogenet. Genomics 16: 881-889 (2006).

• Dai Q, Shrubsole MJ, Ness RM, Schlundt D, Cai Q, Smalley WE, Li M, Shyr Y, Zheng W. The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk. Am. J. Clin. Nutr. 86: 743-751 (2007). *

• Daiss W, Scheurlen M, Malchow H. Epidemiology of inflammatory bowel disease in the county of Tubingen (West Germany). Scand. J. Gastroenterol. Suppl. 170: 39-43 (1989).

• Daly C, Fitzgerald AP, O'Callaghan P, Collins P, Cooney MT, Graham IM; on behalf of the COMAC Group. Homocysteine increases the risk associated with hyperlipidaemia. Eur. J. Cardiovasc. Prev. Rehabil. 16: 150-155 (2009).

• Damen GM, Hol J, de Ruiter L, Bouquet J, Sinaasappel M, van der Woude J, Laman JD, Hop WC, Buller HA, Escher JC, Nieuwenhuis EE. Chemokine production by buccal epithelium as a distinctive feature of pediatric Crohn disease. J. Pediatr. Gastroenterol. Nutr. 42: 142-149 (2006). *

• Danchenko N, Satia JA, Anthony MS. Epidemiology of systemic lupus erythematosus: a comparison of worldwide disease burden. Lupus 15: 308-318 (2006).

• Danese S, Papa A, Saibeni S, Repici A, Malesci A, Vecchi M. Inflammation and coagulation in inflammatory bowel disease: the clot thickens. Am. J. Gastroenterol. 102: 174-186 (2007). *

• Danforth KN, Rodriguez C, Hayes RB, Sakoda LC, Huang WY, Yu K, Calle EE, Jacobs EJ, Chen BE, Andriole GL, Figueroa JD, Yeager M, Platz EA, Michaud DS, Chanock SJ, Thun MJ, Hsing AW. TNF polymorphisms and prostate cancer risk. Prostate 68: 400-407 (2008).

• Dangour AD, Allen E, Elbourne D, Fletcher A, Richards M, Uauy R. Fish consumption and cognitive function among older people in the UK: baseline data from the Opal study. J. Nutr. Health Aging 13: 198-202 (2009).

• Daniel CR, McCullough ML, Patel RC, Jacobs EJ, Flanders WD, Thun MJ, Calle EE. Dietary intake of omega-6 and omega-3 fatty acids and risk of colorectal cancer in a prospective cohort of U.S. men and women. Cancer Epidemiol. Biomarkers Prev. 18: 516-525 (2009).

• Danila MI, Patkar NM, Curtis JR, Saag KG, Teng GG. Biologics and heart failure in rheumatoid arthritis: are we any wiser? Curr. Opin. Rheumatol. 20: 327-333 (2008).

• Danner S, Sordet C, Terzic J, Donato L, Velten M, Fischbach M, Sibilia J. Epidemiology of juvenile idiopathic arthritis in Alsace, France. J. Rheumatol. 33: 1377-1381 (2006).

• Das BB, Recto M, Johnsrude C, Klein L, Orman K, Shoemaker L, Mitchell M, Austin EH. Cardiac transplantation for pediatric giant cell myocarditis. J. Heart Lung Transplant. 25: 474-478 (2006).

• Das JC, Paul N. Epidemiology and pathophysiology of Helicobacter pylori infection in children. Indian J. Pediatr. 74: 287-290 (2007). *

• Das KM. Immunopathogenesis of primary sclerosing cholangitis: possible role of a shared colonic and biliary epithelial antigen. J. Gastroenterol. Hepatol. 19: S290-S294 (2004). *

• Davila JA, El-Serag HB. Racial differences in survival of hepatocellular carcinoma in the United States: a population-based study. Clin. Gastroenterol. Hepatol. 4: 104-110 (2006). *

• Davila JA, Morgan RO, Shaib Y, McGlynn KA, El-Serag HB. Hepatitis C infection and the increasing incidence of hepatocellular carcinoma: a population-based study. Gastroenterology 127: 1372-1380 (2004). *

• Davila JA, Morgan RO, Shaib Y, McGlynn KA, El-Serag HB. Diabetes increases the risk of hepatocellular carcinoma in the United States: a population based case control study. Gut 54: 533-539 (2005). *

• Davis CF, Dorak MT. An extensive analysis of the hereditary hemochromatosis gene HFE and neighboring histone genes: associations with childhood leukemia. Ann. Hematol. Oct 6 [Epub ahead of print] (2009). *

• Daw EW, Heath SC, Lu Y. Single-nucleotide polymorphism versus microsatellite markers in a combined linkage and segregation analysis of a quantitative trait. BMC Genet. 6 Suppl. 1: S32 (2005). *

• Daw EW, Yu R. The feasibility of oligogenic combined segregation and linkage analysis in CEPH pedigrees. BMC Proc. 1 Suppl. 1: S108 (2007). *

• Day IN. dbSNP in the detail and copy number complexities. Hum. Mutat. 31: 2-4 (2009). *

• de Andrade M, Jackow CM, Dahm N, Hordinsky M, Reveille JD, Duvic M. Alopecia areata in families: association with the HLA locus. J. Investig. Dermatol. Symp. Proc. 4: 220-223 (1999). *

• De Block CE, De Leeuw IH, Van Gaal LF. Autoimmune gastritis in type 1 diabetes: a clinically oriented review. J. Clin. Endocrinol. Metab. 93: 363-371 (2008). *

• de Cid R, Riveira-Munoz E, Zeeuwen PL, Robarge J, Liao W, Dannhauser EN, Giardina E, Stuart PE, Nair R, Helms C, Escaramís G, Ballana E, Martín-Ezquerra G, Heijer MD, Kamsteeg M, Joosten I, Eichler EE, Lázaro C, Pujol RM, Armengol L, et al. Deletion of the late cornified envelope LCE3B and LCE3C genes as a susceptibility factor for psoriasis. Nat. Genet. 41: 211-215 (2009). *

• de Dombal FT. Epidemiology of Crohn's disease of the colon. Ann. Gastroenterol. Hepatol. (Paris) 21: 191-200 (1985).

• De Groote D, Ducatelle R, Haesebrouck F. Helicobacters of possible zoonotic origin: a review. Acta Gastroenterol. Belg. 63: 380-387 (2000).

• de Hingh YC, van der Vossen PW, Gemen EF, Mulder AB, Hop WC, Brus F, de Vries E. Intrinsic abnormalities of lymphocyte counts in children with Down syndrome. J. Pediatr. 147: 744-747 (2005). *

• De Jager ME, Van De Kerkhof PC, De Jong EM, Seyger MM. Epidemiology and prescribed treatments in childhood psoriasis: a survey among medical professionals. J. Dermatolog. Treat. Jan 1 [Epub ahead of print] (2009).

• De Jager PL, Simon KC, Munger KL, Rioux JD, Hafler DA, Ascherio A. Integrating risk factors. HLA-DRB1*1501 and Epstein-Barr virus in multiple sclerosis. Neurology 70: 1113-1118 (2008).

• de Jong BA, Huizinga TW, Zanelli E, Giphart MJ, Bollen EL, Uitdehaag BM, Polman CH, Westendorp RG. Evidence for additional genetic risk indicators of relapse-onset MS within the HLA region. Neurology 59: 549-555 (2002).

• de Jong BA, Westendorp RG, Bakker AM, Huizinga TW. Polymorphisms in or near tumour necrosis factor (TNF)-gene do not determine levels of endotoxin-induced TNF production. Genes Immun. 3: 25-29 (2002). *

• de la Fuente-Arrillaga C, Vazquez Ruiz Z, Bes-Rastrollo M, Sampson L, Martinez-Gonzalez MA. Reproducibility of an FFQ validated in Spain. Public Health Nutr. Jan 28 [Epub ahead of print] (2010).

• de Lange T, Svensen AM, Larsen S, Aabakken L. The functionality and reliability of an Internet interface for assessments of endoscopic still images and video clips: distributed research in gastroenterology. Gastrointest. Endosc. 63: 445-452 (2006).

• de Lau LM, Koudstaal PJ, van Meurs JB, Uitterlinden AG, Hofman A, Breteler MM. Methylenetetrahydrofolate reductase C677T genotype and PD. Ann. Neurol. 57: 927-930 (2005).

• De Marco G, Barabino A, Gambarara M, Diamanti A, Martelossi S, Guarino A. Network approach to the child with primary intestinal failure. J. Pediatr. Gastroenterol. Nutr. 43 Suppl. 1: S61-S67 (2006). *

• de Mesquita MB, Civitelli F, Levine A. Epidemiology, genes and inflammatory bowel diseases in childhood. Dig. Liver Dis. 40: 3-11 (2008).

• de Rooij SR, Painter RC, Phillips DI, Osmond C, Tanck MW, Defesche JC, Bossuyt PM, Michels RP, Bleker OP, Roseboom TJ. The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famine. Diabetes Care 29: 1052-1057 (2006). *

• de Silva E, Stumpf MP. HIV and the CCR5-Delta32 resistance allele. FEMS Microbiol. Lett. 241: 1-12 (2004). *

• De Staercke C, Lally C, Austin H, Winston C, Dowling N, Williams B, Craig Hooper W. The lack of association between four point mutations in the promoter region of the Toll-like 4 receptor gene and myocardial infarction. Thromb. Res. 119: 105-110 (2007). *

• De Stavola BL, Christensen E. Multilevel models for longitudinal variables prognostic for survival. Lifetime Data Anal. 2: 329-347 (1996).

• Dealberto MJ. Why are immigrants at increased risk for psychosis? Vitamin D insufficiency, epigenetic mechanisms, or both? Med. Hypotheses 68: 259-267 (2007).

• Dehghan A, Yang Q, Peters A, Basu S, Bis JC, Rudnicka AR, Kavousi M, Chen MH, Baumert J, Lowe GD, McKnight B, Tang W, de Maat M, Larson MG, Eyhermendy S, McArdle WL, Lumley T, Pankow JS, Hofman A, Massaro JM, Rivadeneira F, Kolz M, Taylor KD, et al. Association of novel genetic loci with circulating fibrinogen levels: a genome-wide association study in 6 population-based cohorts. Circ. Cardiovasc. Genet. 2: 125-133 (2009).

• Deighton C, Hyrich K. Why do the French get much greater access to anti-TNF than the British? Vive la difference? Pas necessairement. Rheumatology (Oxford) 47: 1600-1602 (2008). *

• Dejaco C, Harrer M, Waldhoer T, Miehsler W, Vogelsang H, Reinisch W. Antibiotics and azathioprine for the treatment of perianal fistulas in Crohn's disease. Aliment. Pharmacol. Ther. 18: 1113-1120 (2003). *

• Delcourt C. Application of nutrigenomics in eye health. Forum Nutr. 60: 168-175 (2007).

• Delgado J, Sperber AD, Novack V, Delgado B, Edelman L, Gaspar N, Krugliak P, Odes S, Jotkowitz AB, Faszczyk M, Fich A. The epidemiology of primary biliary cirrhosis in southern Israel. Isr. Med. Assoc. J. 7: 717-721 (2005). *

• Delgado-Vega AM, Martin J, Granados J, Anaya JM. Genetic epidemiology of rheumatoid arthritis: what to expect from Latin America? Biomedica 26: 562-584 (2006).

• Deming SL, Zheng W, Xu WH, Cai Q, Ruan Z, Xiang YB, Shu XO. UGT1A1 genetic polymorphisms, endogenous estrogen exposure, soy food intake, and endometrial cancer risk. Cancer Epidemiol. Biomarkers Prev. 17: 563-570 (2008). *

• Dempfle A, Hein R, Beckmann L, Scherag A, Nguyen TT, Schafer H, Chang-Claude J. Comparison of the power of haplotype-based versus single- and multilocus association methods for gene x environment (gene x sex) interactions and application to gene x smoking and gene x sex interactions in rheumatoid arthritis. BMC Proc. 1 Suppl. 1: S73 (2007). *

• Dennison E, Syddall H, Fall C, Brandi ML, Cooper C. Evidence of sexual dimorphism in relationships between estrogen receptor polymorphisms and bone mass: the Hertfordshire study. J. Rheumatol. 32: 2400-2404 (2005).

• Deodhar NS. Epidemiological perspective of domestic and personal hygiene in India. Int. J. Environ. Health Res. 13 Suppl. 1: S47-S56 (2003).

• Desai HG, Gupte PA. Increasing incidence of Crohn's disease in India: is it related to improved sanitation? Indian J. Gastroenterol. 24: 23-24 (2005). *

• Deshmukh H, Kim-Howard X, Nath SK. Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis data. BMC Proc. 3 Suppl. 7: S31 (2009). *

• Deshpande LM, Fritsche TR, Moet GJ, Biedenbach DJ, Jones RN. Antimicrobial resistance and molecular epidemiology of vancomycin-resistant enterococci from North America and Europe: a report from the SENTRY antimicrobial surveillance program. Diagn. Microbiol. Infect. Dis. 58: 163-170 (2007).

• Deutekom M, Dobben AC, Terra MP, Engel AF, Stoker J, Bossuyt PM, Boeckxstaens GE. Clinical presentation of fecal incontinence and anorectal function: what is the relationship? Am. J. Gastroenterol. 102: 351-361 (2007). *

• Deuter CM, Kotter I, Wallace GR, Murray PI, Stubiger N, Zierhut M. Behcet's disease: ocular effects and treatment. Prog. Retin. Eye Res. 27: 111-136 (2008).

• Dewan A, Liu M, Hartman S, Zhang S, Liu DT, Zhao C, Tam PO, Chan WM, Lam DS, Snyder M, Barnstable C, Pang CP, Hoh J. HTRA1 promoter polymorphism in wet age-related macular degeneration. Science 314: 989-992 (2006). *

• di Giuseppe R, de Lorgeril M, Salen P, Laporte F, Di Castelnuovo A, Krogh V, Siani A, Arnout J, Cappuccio FP, van Dongen M, Donati MB, de Gaetano G, Iacoviello L; on behalf of the European Collaborative Group of the IMMIDIET Project. Alcohol consumption and n-3 polyunsaturated fatty acids in healthy men and women from 3 European populations. Am. J. Clin. Nutr. 89: 354-362 (2009). *

• Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study Research Group, Jacobson AM, Musen G, Ryan CM, Silvers N, Cleary P, Waberski B, Burwood A, Weinger K, Bayless M, Dahms W, Harth J. Long-term effect of diabetes and its treatment on cognitive function. N. Engl. J. Med. 356: 1842-1852 (2007). *

• Dial S, Delaney JA, Schneider V, Suissa S. Proton pump inhibitor use and risk of community-acquired Clostridium difficile-associated disease defined by prescription for oral vancomycin therapy. CMAJ 175: 745-748 (2006). *

• Dimagno MJ, Dimagno EP. New advances in acute pancreatitis. Curr. Opin. Gastroenterol. 23: 494-501 (2007).

• Ding C, Cicuttini F, Li J, Jones G. Targeting IL-6 in the treatment of inflammatory and autoimmune diseases. Expert Opin. Investig. Drugs 18: 1457-1466 (2009).

• Ding EL, Song Y, Manson JE, Hunter DJ, Lee CC, Rifai N, Buring JE, Gaziano JM, Liu S. Sex hormone-binding globulin and risk of type 2 diabetes in women and men. N. Engl. J. Med. 361: 1152-1163 (2009). *

• Ding YC, Weizman Z, Yerushalmi B, Elbedour K, Garner CP, Neuhausen SL. An autosomal genome-wide screen for celiac disease in Bedouin families. Genes Immun. 9: 81-86 (2008). *

• Diplock AT. Antioxidant nutrients and disease prevention: an overview. Am. J. Clin. Nutr. 53: 189S-193S (1991).

• Dixon W, Silman A. Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al. Arthritis Res. Ther. 8: 111 (2006). *

• Domingues RB. Treatment of viral encephalitis. Cent. Nerv. Syst. Agents Med. Chem. 9: 56-62 (2009).

• Donaldson EF, Yount B, Sims AC, Burkett S, Pickles RJ, Baric RS. Systematic assembly of a full-length infectious clone of human coronavirus NL63. J. Virol. 82: 11948-11957 (2008). *

• Donaldson MR, Book LS, Leiferman KM, Zone JJ, Neuhausen SL. Strongly positive tissue transglutaminase antibodies are associated with Marsh 3 histopathology in adult and pediatric celiac disease. J. Clin. Gastroenterol. 42: 256-260 (2008).

• Dong H, Yauk CL, Williams A, Lee A, Douglas GR, Wade MG. Hepatic gene expression changes in hypothyroid juvenile mice: characterization of a novel negative thyroid responsive element. Endocrinology 148: 3932-3940 (2007). *

• Donn R, Payne D, Ray D. Glucocorticoid receptor gene polymorphisms and susceptibility to rheumatoid arthritis. Clin. Endocrinol. (Oxf.) 67: 342-345 (2007). *

• Donn RP, Plant D, Jury F, Richards HL, Worthington J, Ray DW, Griffiths CE. Macrophage migration inhibitory factor gene polymorphism is associated with psoriasis. J. Invest. Dermatol. 123: 484-487 (2004). *

• Donn RP, Thomson W, Pepper L, Carthy D, Farhan A, Ryder C, Southwood T, Holt L, Ollier W. Antinuclear antibodies in early onset pauciarticular juvenile chronic arthritis (JCA) are associated with HLA-DQB1*0603: a possible JCA-associated human leucocyte antigen haplotype. Br. J. Rheumatol. 34: 461-465 (1995).

• Doorduyn Y, Van Pelt W, Siezen CL, Van Der Horst F, Van Duynhoven YT, Hoebee B, Janssen R. Novel insight in the association between Salmonellosis or Campylobacteriosis and chronic illness, and the role of host genetics in susceptibility to these diseases. Epidemiol. Infect. 136: 1225-1234 (2008).

• Dorak MT, Shao W, Machulla HK, Lobashevsky ES, Tang J, Park MH, Kaslow RA. Conserved extended haplotypes of the major histocompatibility complex: further characterization. Genes Immun. 7: 450-467 (2006). *

• Dorak MT, Yee LJ, Tang J, Shao W, Lobashevsky ES, Jacobson LP, Kaslow RA. HLA-B, -DRB1/3/4/5, and -DQB1 gene polymorphisms in human immunodeficiency virus-related Kaposi's sarcoma. J. Med. Virol. 76: 302-310 (2005). *

• Dore GJ, Hellard M, Matthews G, Grebely J, Haber PS, Petoumenos K, Yeung B, Marks P, van Beek I, McCaughan G, White P, Ffrench R, Rawlinson W, Lloyd AR, Kaldor JM; ATAHC Study Group. Effective treatment of injecting drug users with recently acquired hepatitis C virus infection. Gastroenterology 138: 123-135.e2 (2010). *

• Doria A, Wojcik J, Xu R, Gervino EV, Hauser TH, Johnstone MT, Nolan D, Hu FB, Warram JH. Interaction between poor glycemic control and 9p21 locus on risk of coronary artery disease in type 2 diabetes. JAMA 300: 2389-2397 (2008). *

• Doria-Rose VP, Levin TR, Selby JV, Newcomb PA, Richert-Boe KE, Weiss NS. The incidence of colorectal cancer following a negative screening sigmoidoscopy: implications for screening interval. Gastroenterology 127: 714-722 (2004). *

• Dorman J, Steenkiste A, O'Leary L, McCarthy B, Lorenzen T, Foley T. Type 1 diabetes in offspring of parents with type 1 diabetes: the tip of an autoimmune iceberg? Pediatr. Diabetes 1: 17-22 (2000).

• Dorner M, Brandt S, Tinguely M, Zucol F, Bourquin JP, Zauner L, Berger C, Bernasconi M, Speck RF, Nadal D. Plasma cell Toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production. Immunology 128: 573-579 (2009). *

• Douglas RS, Brix TH, Hwang CJ, Hegedus L, Smith TJ. Divergent frequencies of IGF-1 receptor-expressing blood lymphocytes in monozygotic twin pairs discordant for Graves' disease: evidence for a phenotypic signature ascribable to non-genetic factors. J. Clin. Endocrinol. Metab. 94: 1797-1802 (2009).

• Driscoll JA, Brody SL, Kollef MH. The epidemiology, pathogenesis and treatment of Pseudomonas aeruginosa infections. Drugs 67: 351-368 (2007).

• Duell EJ, Holly EA, Kelsey KT, Bracci PM. Genetic variation in CYP17A1 and pancreatic cancer in a population-based case-control study in the San Francisco Bay Area, California. Int. J. Cancer 126: 790-795 (2009). *

• Duerr CU, Zenk SF, Chassin C, Pott J, Gutle D, Hensel M, Hornef MW. O-antigen delays lipopolysaccharide recognition and impairs antibacterial host defense in murine intestinal epithelial cells. PLoS Pathog. 5: e1000567 (2009). *

• Duetsch G, Illig T, Loesgen S, Rohde K, Klopp N, Herbon N, Gohlke H, Altmueller J, Wjst M. STAT6 as an asthma candidate gene: polymorphism-screening, association and haplotype analysis in a Caucasian sib-pair study. Hum. Mol. Genet. 11: 613-621 (2002). *

• Duffy DL. Genetic determinants of diabetes are similarly associated with other immune-mediated diseases. Curr. Opin. Allergy Clin. Immunol. 7: 468-474 (2007).

• Duggal P, An P, Beaty TH, Strathdee SA, Farzadegan H, Markham RB, Johnson L, O'Brien SJ, Vlahov D, Winkler CA. Genetic influence of CXCR6 chemokine receptor alleles on PCP-mediated AIDS progression among African Americans. Genes Immun. 4: 245-250 (2003). *

• Duggan JM, Duggan AE. Systematic review: the liver in coeliac disease. Aliment. Pharmacol. Ther. 21: 515-518 (2005). *

• Dultz G, Matheis N, Dittmar M, Rohrig B, Bender K, Kahaly GJ. The protein tyrosine phosphatase non-receptor type 22 C1858T polymorphism is a joint susceptibility locus for immunthyroiditis and autoimmune diabetes. Thyroid 19: 143-148 (2009).

• Dumonceau JM, Adler M, Cremer M, Van Gossum A. The role of infectious agents in Crohn's disease. Acta Gastroenterol. Belg. 57: 301-305 (1994).

• Dupont HL. Systematic review: the epidemiology and clinical features of travellers' diarrhoea. Aliment. Pharmacol. Ther. 30: 187-196 (2009). *

• DuPont HL, Garey K, Caeiro JP, Jiang ZD. New advances in Clostridium difficile infection: changing epidemiology, diagnosis, treatment and control. Curr. Opin. Infect. Dis. 21: 500-507 (2008).

• Duvic M, Norris D, Christiano A, Hordinsky M, Price V. Alopecia areata registry: an overview. J. Investig. Dermatol. Symp. Proc. 8: 219-221 (2003). *

• Duvoux C. Epidemiology and diagnosis of hepatocellular carcinomas in cirrhosis. Ann. Chir. 52: 511-517 (1998).

• Eastell T, Hinks A, Thomson W. SNPs in the FOXP3 gene region show no association with juvenile idiopathic arthritis in a UK Caucasian population. Rheumatology (Oxford) 46: 1263-1265 (2007). *

• Easton DF, Pooley KA, Dunning AM, Pharoah PD, Thompson D, Ballinger DG, Struewing JP, Morrison J, Field H, Luben R, Wareham N, Ahmed S, Healey CS, Bowman R, et al. Genome-wide association study identifies novel breast cancer susceptibility loci. Nature 447: 1087-1093 (2007). *

• Eaton WW, Rose NR, Kalaydjian A, Pedersen MG, Mortensen PB. Epidemiology of autoimmune diseases in Denmark. J. Autoimmun. 29: 1-9 (2007).

• Edelstein ZR, Bronner MP, Rosen SN, Vaughan TL. Risk factors for Barrett's esophagus among patients with gastroesophageal reflux disease: a community clinic-based case-control study. Am. J. Gastroenterol. 104: 834-842 (2009). *

• Edmond KM, Quigley MA, Zandoh C, Danso S, Hurt C, Agyei SO, Kirkwood BR. Diagnostic accuracy of verbal autopsies in ascertaining the causes of stillbirths and neonatal deaths in rural Ghana. Paediatr. Perinat. Epidemiol. 22: 417-429 (2008).

• Efrati O, Nir J, Fraser D, Cohen-Cymberknoh M, Shoseyov D, Vilozni D, Modan-Moses D, Levy R, Szeinberg A, Kerem E, Rivlin J. Meconium ileus in patients with cystic fibrosis is not a risk factor for clinical deterioration and survival: the Israeli multicenter study. J. Pediatr. Gastroenterol. Nutr. Aug 4 [Epub ahead of print] (2009).

• Eggleston A, Katelaris PH, Nandurkar S, Thorpe P, Holtmann G; on behalf of the TREAT study group. Clinical trial: the treatment of gastro-oesophageal reflux disease in primary care - prospective randomized comparison of rabeprazole 20 mg with esomeprazole 20 and 40 mg. Aliment. Pharmacol. Ther. 29: 967-978 (2009). *

• Ehrenfeld M. Geoepidemiology: the environment and spondyloarthropathies. Autoimmun. Rev. Dec 16 [Epub ahead of print] (2009).

• Ehrhardt M, Lindenmaier H, Burhenne J, Haefeli WE, Weiss J. Influence of lipid lowering fibrates on P-glycoprotein activity in vitro. Biochem. Pharmacol. 67: 285-292 (2004). *

• Ekbom A. The epidemiology of IBD: a lot of data but little knowledge. How shall we proceed? Inflamm. Bowel Dis. 10 Suppl. 1: S32-S34 (2004). *

• Ekbom A. Paratuberculosis and Crohn's disease - possible linkage? Acta Vet. Scand. 44: 267-268 (2003).

• Ekbom A. Can we predict the natural history of IBD? Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, pp. 29-30 (2006). *

• Ekbom A. Review: substantial coffee consumption was associated with a lower risk of colorectal cancer in the general population. Gut 44: 597 (1999). *

• Ekbom A. Risk factors and distinguishing features of cancer in IBD. Inflamm. Bowel Dis. 4: 235-243 (1998). *

• Ekbom A, Brandt L, Granath F, Lofdahl CG, Egesten A. Increased risk of both ulcerative colitis and Crohn's disease in a population suffering from COPD. Lung 186: 167-172 (2008).

• Ekbom A, Daszak P, Kraaz W, Wakefield AJ. Crohn's disease after in-utero measles virus exposure. Lancet 348: 515-517 (1996). *

• Ekbom A, Helmick C, Zack M, Adami HO. The epidemiology of inflammatory bowel disease: a large, population-based study in Sweden. Gastroenterology 100: 350-358 (1991).

• Ekbom A, Montgomery SM. Environmental risk factors (excluding tobacco and microorganisms): critical analysis of old and new hypotheses. Best Pract. Res. Clin. Gastroenterol. 18: 497-508 (2004).

• Ekbom A, Wakefield AJ, Zack M, Adami HO. Perinatal measles infection and subsequent Crohn's disease. Lancet 344: 508-510 (1994).

• Eknoyan G. Chronic kidney disease definition and classification: the quest for refinements. Kidney Int. 72: 1183-1185 (2007). *

• Ekstrom Smedby K, Vajdic CM, Falster M, Engels EA, Martinez-Maza O, Turner J, Hjalgrim H, Vineis P, Seniori Costantini A, Bracci PM, Holly EA, Willett E, Spinelli JJ, La Vecchia C, Zheng T, Becker N, De Sanjose S, Chiu BC, Dal Maso L, Cocco P, et al. Autoimmune disorders and risk of non-Hodgkin lymphoma subtypes: a pooled analysis within the InterLymph Consortium. Blood 111: 4029-4038 (2008). *

• El Achhab Y, Meyre D, Bouatia-Naji N, Berraho M, Deweirder M, Vatin V, Delplanque J, Serhier Z, Lyoussi B, Nejjari C, Froguel P, Chikri M. Association of the ENPP1 K121Q polymorphism with type 2 diabetes and obesity in the Moroccan population. Diabetes Metab. 35: 37-42 (2009).

• El Mouzan MI, Abdullah AM, Al Habbal MT. Epidemiology of juvenile-onset inflammatory bowel disease in Central Saudi Arabia. J. Trop. Pediatr. 52: 69-71 (2006).

• El-Magadmi M, Alansari A, Teh LS, Ordi J, Gul A, Inanc M, Bruce I, Hajeer A. Association of the A561C E-selectin polymorphism with systemic lupus erythematosus in 2 independent populations. J. Rheumatol. 28: 2650-2652 (2001).

• El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology 132: 2557-2576 (2007). *

• Eland IA, Sundstrom A, Velo GP, Andersen M, Sturkenboom MC, Langman MJ, Stricker BH, Wiholm B, For The Edip Study Group Of The European Pharmacovigilance Research Group. Antihypertensive medication and the risk of acute pancreatitis: the European case-control study on drug-induced acute pancreatitis (EDIP). Scand. J. Gastroenterol. 41: 1484-1490 (2006). *

• Elder JT, Bruce AT, Gudjonsson JE, Johnston A, Stuart PE, Tejasvi T, Voorhees JJ, Abecasis GR, Nair RP. Molecular dissection of psoriasis: integrating genetics and biology. J. Invest. Dermatol. Oct 8 [Epub ahead of print] (2009). *

• Elfstrom P, Montgomery SM, Kampe O, Ekbom A, Ludvigsson JF. Risk of thyroid disease in individuals with celiac disease. J. Clin. Endocrinol. Metab. 93: 3915-3921 (2008). *

• Elfstrom P, Montgomery SM, Kampe O, Ekbom A, Ludvigsson JF. Risk of primary adrenal insufficiency in patients with celiac disease. J. Clin. Endocrinol. Metab. 92: 3595-3598 (2007). *

• Elkjaer M, Burisch J, Avnstrom S, Lynge E, Munkholm P. Development of a web-based concept for patients with ulcerative colitis and 5-aminosalicylic acid treatment. Eur. J. Gastroenterol. Hepatol. Jun 18 [Epub ahead of print] (2009).

• Ellis JA, Munro JE, Ponsonby AL. Possible environmental determinants of juvenile idiopathic arthritis. Rheumatology (Oxford) 49: 411-425 (2010).

• Emerit J, Congy F, Loeper J. Recent data on the epidemiology and etiology of Crohn's disease. Nouv. Presse. Med. 11: 3195-3200 (1982).

• Engels EA, Cerhan JR, Linet MS, Cozen W, Colt JS, Davis S, Gridley G, Severson RK, Hartge P. Immune-related conditions and immune-modulating medications as risk factors for non-Hodgkin's lymphoma: a case-control study. Am. J. Epidemiol. 162: 1153-1161 (2005). *

• Ennis S, Jomary C, Mullins R, Cree A, Chen X, Macleod A, Jones S, Collins A, Stone E, Lotery A. Association between the SERPING1 gene and age-related macular degeneration: a two-stage case-control study. Lancet 372: 1828-1834 (2008). *

• Epplein M, Wilkens LR, Tiirikainen M, Dyba M, Chung FL, Goodman MT, Murphy SP, Henderson BE, Kolonel LN, Le Marchand L. Urinary isothiocyanates, glutathione S-transferase M1, T1, and P1 polymorphisms, and risk of colorectal cancer: the multiethnic cohort study. Cancer Epidemiol. Biomarkers Prev. 18: 314-320 (2009).

• Erichsen R, Jepsen P, Vilstrup H, Ekbom A, Sorensen HT. Incidence and prognosis of cholangiocarcinoma in Danish patients with and without inflammatory bowel disease: a national cohort study, 1978-2003. Eur. J. Epidemiol. 24: 513-520 (2009).

• Erikstrup C, Kronborg G, Lohse N, Rye Ostrowski S, Gerstoft J, Ullum H. T-cell dysfunction in HIV-1-infected patients with impaired recovery of CD4 cells despite suppression of viral replication. J. Acquir. Immune Defic. Syndr. Dec 31 [Epub ahead of print] (2009).

• Erlich HA. HLA class II sequences and genetic susceptibility to insulin dependent diabetes mellitus. Baillieres Clin. Endocrinol. Metab. 5: 395-411 (1991).

• Erlinger TP, Platz EA, Rifai N, Helzlsouer KJ. C-reactive protein and the risk of incident colorectal cancer. JAMA 291: 585-590 (2004). *

• Escorsell A, Pares A, Rodes J, Solis-Herruzo JA, Miras M, de la Morena E. Epidemiology of primary sclerosing cholangitis in Spain. Spanish Association for the Study of the Liver. J. Hepatol. 21: 787-791 (1994).

• Etemadifar M, Janghorbani M, Shaygannejad V, Ashtari F. Prevalence of multiple sclerosis in Isfahan, Iran. Neuroepidemiology 27: 39-44 (2006).

• Etminan M, Levesque L, Fitzgerald JM, Brophy JM. Risk of upper gastrointestinal bleeding with oral bisphosphonates and non steroidal anti-inflammatory drugs: a case-control study. Aliment. Pharmacol. Ther. 29: 1188-1192 (2009). *

• Etzel CJ, Chen WV, Shepard N, Jawaheer D, Cornelis F, Seldin MF, Gregersen PK, Amos CI; for the North American Rheumatoid Arthritis Consortium. Genome-wide meta-analysis for rheumatoid arthritis. Hum. Genet. 119: 634-641 (2006). *

• Evereklioglu C. Current concepts in the etiology and treatment of Behcet disease. Surv. Ophthalmol. 50: 297-350 (2005).

• Everhart JE. Recent developments in the epidemiology of Helicobacter pylori. Gastroenterol. Clin. North Am. 29: 559-578 (2000).

• Eyles D, Almeras L, Benech P, Patatian A, Mackay-Sim A, McGrath J, Feron F. Developmental vitamin D deficiency alters the expression of genes encoding mitochondrial, cytoskeletal and synaptic proteins in the adult rat brain. J. Steroid Biochem. Mol. Biol. 103: 538-545 (2007).

• Eyre S, Barton A, Shephard N, Hinks A, Brintnell W, MacKay K, Silman A, Ollier W, Wordsworth P, John S, Worthington J. Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs. Arthritis Rheum. 50: 729-735 (2004). *

• Falchi M, Bataille V, Hayward NK, Duffy DL, Bishop JA, Pastinen T, Cervino A, Zhao ZZ, Deloukas P, Soranzo N, Elder DE, Barrett JH, Martin NG, Bishop DT, Montgomery GW, Spector TD. Genome-wide association study identifies variants at 9p21 and 22q13 associated with development of cutaneous nevi. Nat. Genet. 41: 915-919 (2009). *

• Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, Steel G, Nestadt G, Liang KY, Huganir RL, Valle D, Pulver AE. Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. Am. J. Hum. Genet. 77: 918-936 (2005). *

• Fan CH, Jin MJ, Zhang Y, Song L, Xu H, Jiang QT, Yu WP, Chen K. Association between genetic polymorphisms of metabolic enzymes and susceptibility of colorectal cancer. Zhonghua Yu Fang Yi Xue Za Zhi 40: 13-17 (2006).

• Fan JG, Farrell GC. Epidemiology of non-alcoholic fatty liver disease in China. J. Hepatol. 50: 204-210 (2009). *

• Fang W, Yang P. Vogt-Koyanagi-Harada syndrome. Curr. Eye Res. 33: 517-523 (2008).

• Fang Y, van Meurs JB, Rivadeneira F, van Schoor NM, van Leeuwen JP, Lips P, Pols HA, Uitterlinden AG. Vitamin D receptor gene haplotype is associated with body height and bone size. J. Clin. Endocrinol. Metab. 92: 1491-1501 (2007). *

• Farheen S, Sengupta S, Santra A, Pal S, Dhali GK, Chakravorty M, Majumder PP, Chowdhury A. Gilbert's syndrome: high frequency of the (TA) (7) TAA allele in India and its interaction with a novel CAT insertion in promoter of the gene for bilirubin UDP-glucuronosyltransferase 1 gene. World J. Gastroenterol. 12: 2269-2275 (2006). *

• Farley E, Masrour S, McKey J, Menter A. Palmoplantar psoriasis: a phenotypical and clinical review with introduction of a new quality-of-life assessment tool. J. Am. Acad. Dermatol. 60: 1024-1031 (2009).

• Farmer DG, Seu P, Swenson K, Economou J, Busuttil RW. Current and future treatment modalities for hepatocellular carcinoma. Clin. Liver Dis. 1: 361-396, ix (1997).

• Farrell FJ, Keeffe EB. Diabetes and the hepatobiliary system. Clin. Liver Dis. 2: 119-131, vii (1998).

• Farrell P, Joffe S, Foley L, Canny GJ, Mayne P, Rosenberg M. Diagnosis of cystic fibrosis in the Republic of Ireland: epidemiology and costs. Ir. Med. J. 100: 557-560 (2007).

• Farrokhyar F, Marshall JK, Easterbrook B, Irvine EJ. Functional gastrointestinal disorders and mood disorders in patients with inactive inflammatory bowel disease: prevalence and impact on health. Inflamm. Bowel Dis. 12: 38-46 (2006). *

• Fasolato S, Angeli P, Dallagnese L, Maresio G, Zola E, Mazza E, Salinas F, Dona S, Fagiuoli S, Sticca A, Zanus G, Cillo U, Frasson I, Destro C, Gatta A. Renal failure and bacterial infections in patients with cirrhosis: epidemiology and clinical features. Hepatology 45: 223-229 (2007). *

• Fausa O, Schrumpf E, Elgjo K. Relationship of inflammatory bowel disease and primary sclerosing cholangitis. Semin. Liver Dis. 11: 31-39 (1991).

• Feagan B. Infliximab, adalimumab and certolizumab: beneficial and adverse effects (past). Inflamm. Bowel Dis. 12 Suppl. 3: S6 (2006).

• Feagan BG, Coteur G, Tan S, Keininger DL, Schreiber S. Clinically meaningful improvement in health-related quality of life in a randomized controlled trial of certolizumab pegol maintenance therapy for Crohn's disease. Am. J. Gastroenterol. 104: 1976-1983 (2009). *

• Feillet H, Bach JF. Increased incidence of inflammatory bowel disease: the price of the decline of infectious burden? Curr. Opin. Gastroenterol. 20: 560-564 (2004).

• Feld J, Heathcote E. Epidemiology of autoimmune liver disease. J. Gastroenterol. Hepatol. 18: 1118-1128 (2003). *

• Fermin CD, Garry RF. Possible involvement of a recently discovered human retrovirus in idiopathic immunologic disorders, including Sjogren syndrome (autoimmune exocrinopathy). HNO 41: 239-249 (1993).

• Fernandez-Banares F, Esteve-Comas M, Rosinach M. Screening for celiac disease in high risk groups. Gastroenterol. Hepatol. 28: 561-566 (2005).

• Fernberg P, Chang ET, Duvefelt K, Hjalgrim H, Eloranta S, Sorensen KM, Porwit A, Humphreys K, Melbye M, Ekstrom Smedby K. Genetic variation in chromosomal translocation breakpoint and immune function genes and risk of non-Hodgkin lymphoma. Cancer Causes Control Jan 20 [Epub ahead of print] (2010). *

• Ferraris A, Torres B, Knafelz D, Barabino A, Lionetti P, de Angelis GL, Iacono G, Papadatou B, D'Amato G, Di Ciommo V, Dallapiccola B, Castro M. Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study. Inflamm. Bowel Dis. 12: 355-361 (2006).

• Ferreiros-Vidal I, D'Alfonso S, Papasteriades C, Skopouli FN, Marchini M, Scorza R, Migliaresi S, Sebastiani GD, Endreffy E, Mavromati M, Kappou-Rigatou I, Ruzickova S, Dostal C, Schmidt RE, Witte T, Gomez-Reino JJ, Gonzalez A. Bias in association studies of systemic lupus erythematosus susceptibility due to geographical variation in the frequency of a programmed cell death 1 polymorphism across Europe. Genes Immun. 8: 138-146 (2007). *

• Ferrer M. Epidemiology, healthcare, resources, use and clinical features of different types of urticaria. Alergologica 2005. J. Investig. Allergol. Clin. Immunol 19 Suppl. 2: 21-26 (2009).

• Ferris I Tortajada J, Ortega Garcia JA, Garcia I Castell J, Lopez Andreu JA, Ribes Koninckx C, Berbel Tornero O. Risks factors for pediatric malignant liver tumors. An. Pediatr. (Barc.) 68: 377-384 (2008).

• Ferrucci L, Cherubini A, Bandinelli S, Bartali B, Corsi A, Lauretani F, Martin A, Andres-Lacueva C, Senin U, Guralnik JM. Relationship of plasma polyunsaturated fatty acids to circulating inflammatory markers. J. Clin. Endocrinol. Metab. 91: 439-446 (2006). *

• Ferrucci LM, Sinha R, Graubard BI, Mayne ST, Ma X, Schatzkin A, Schoenfeld PS, Cash BD, Flood A, Cross AJ. Dietary meat intake in relation to colorectal adenoma in asymptomatic women. Am. J. Gastroenterol. 104: 1231-1240 (2009). *

• Fesinmeyer MD, Stanford JL, Brentnall TA, Mandelson MT, Farin FM, Srinouanprachanh S, Afsharinejad Z, Goodman GE, Barnett MJ, Austin MA. Association between the peroxisome proliferator-activated receptor gamma Pro12Ala variant and haplotype and pancreatic cancer in a high-risk cohort of smokers: a pilot study. Pancreas 38: 631-637 (2009).

• Festini F, Taccetti G, Galici V, Neri S, Bisogni S, Ciofi D, Braggion C. A 1-m distance is not safe for children with cystic fibrosis at risk for cross-infection with Pseudomonas aeruginosa. Am. J. Infect. Control Feb 1 [Epub ahead of print] (2010).

• Feudjo-Tepie MA, Le Roux G, Beach KJ, Bennett D, Robinson NJ. Comorbidities of idiopathic thrombocytopenic purpura: a population-based study. Adv. Hematol. 2009: 963506 (2009).

• Filippini N, Zarei M, Beckmann CF, Galluzzi S, Borsci G, Testa C, Bonetti M, Beltramello A, Ghidoni R, Benussi L, Binetti G, Frisoni GB. Regional atrophy of transcallosal prefrontal connections in cognitively normal APOE epsilon4 carriers. J. Magn. Reson. Imaging 29: 1021-1026 (2009).

• Fink S, Schilsky ML. Inherited metabolic disease of the liver. Curr. Opin. Gastroenterol. 23: 237-243 (2007).

• Fiocchi C. Inflammatory bowel disease. Current concepts of pathogenesis and implications for therapy. Minerva Gastroenterol. Dietol. 48: 215-226 (2002).

• Fiocchi C. The multifactorial pathogenesis of IBD. Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, pp. 21-22 (2006). *

• Fischbach W, Malfertheiner P, Hoffmann JC, Bolten W, Kist M, Koletzko S. Helicobacter pylori and gastroduodenal ulcer disease. Dtsch. Arztebl. Int. 106: 801-808 (2009). *

• Fisher E, Li Y, Burwinkel B, Kuhr V, Hoffmann K, Mohlig M, Spranger J, Pfeiffer A, Boeing H, Schrezenmeir J, Doring F. Preliminary evidence of FABP2 A54T polymorphism associated with reduced risk of type 2 diabetes and obesity in women from a German cohort. Horm. Metab. Res. 38: 341-345 (2006).

• Fisher E, Schulze MB, Stefan N, Haring HU, Doring F, Joost HG, Al-Hasani H, Boeing H, Pischon T. Association of the FTO rs9939609 single nucleotide polymorphism with C-reactive protein levels. Obesity (Silver Spring) 17: 330-334 (2009). *

• Fisher SG, Fisher RI. The epidemiology of non-Hodgkin's lymphoma. Oncogene 23: 6524-6534 (2004). *

• Flachenecker P. Epidemiology of neuroimmunological diseases. J. Neurol. 253 Suppl. 5: v2-v8 (2006). *

• Fleming KM, Aithal GP, Solaymani-Dodaran M, Card TR, West J. Incidence and prevalence of cirrhosis in the United Kingdom, 1992-2001: a general population-based study. J. Hepatol. 49: 732-738 (2008). *

• Fletcher KR, Cinalli M. Identification, optimal management, and infection control measures for Clostridium difficile-associated disease in long-term care. Geriatr. Nurs. 28: 171-181 (2007).

• Flores J, Okhuysen PC. Enteroaggregative Escherichia coli infection. Curr. Opin. Gastroenterol. 25: 8-11 (2009).

• Florez JC, Jablonski KA, Sun MW, Bayley N, Kahn SE, Shamoon H, Hamman RF, Knowler WC, Nathan DM, Altshuler D. Effects of the type 2 diabetes-associated PPARG P12A polymorphism on progression to diabetes and response to troglitazone. J. Clin. Endocrinol. Metab. 92: 1502-1509 (2007). *

• Florez O, Zafra G, Morillo C, Martin J, Gonzalez CI. Interleukin-1 gene cluster polymorphism in Chagas disease in a Colombian case-control study. Hum. Immunol. 67: 741-748 (2006).

• Florin TH, Pandeya N, Radford-Smith GL. Epidemiology of appendicectomy in primary sclerosing cholangitis and ulcerative colitis: its influence on the clinical behaviour of these diseases. Gut 53: 973-979 (2004). *

• Florin TH, Woods HJ. Inhibition of methanogenesis by human bile. Gut 37: 418-421 (1995). *

• Folsom AR, Cushman M, Heckbert SR, Ohira T, Rasmussen-Torvik L, Tsai MY. Factor VII coagulant activity, factor VII -670A/C and -402G/A polymorphisms, and risk of venous thromboembolism. J. Thromb. Haemost. 5: 1674-1678 (2007). *

• Folsom AR, Peacock JM, Boerwinkle E, Cushman M. beta2-Adrenergic receptor polymorphism and venous thromboembolism. Thromb. Haemost. 99: 240 (2008).

• Fonager K, Sorensen HT, Mellemkjaer L, Olsen JH, Olsen J. Risk of colorectal cancer in relatives of patients with inflammatory bowel disease (Denmark). Cancer Causes Control 9: 389-392 (1998). *

• Forman JP, Fisher ND, Pollak MR, Cox DG, Tonna S, Curhan GC. Renin-angiotensin system polymorphisms and risk of hypertension: influence of environmental factors. J. Clin. Hypertens. (Greenwich) 10: 459-466 (2008).

• Forman JP, Giovannucci E, Holmes MD, Bischoff-Ferrari HA, Tworoger SS, Willett WC, Curhan GC. Plasma 25-hydroxyvitamin D levels and risk of incident hypertension. Hypertension 49: 1063-1069 (2007).

• Forooghian F, Macdonald IM, Heckenlively JR, Heon E, Gordon LK, Hooks JJ, Detrick B, Nussenblatt RB. The need for standardization of antiretinal antibody detection and measurement. Am. J. Ophthalmol. 146: 489-495 (2008). *

• Forsti A, Lei H, Tavelin B, Enquist K, Palmqvist R, Altieri A, Hallmans G, Hemminki K, Lenner P. Polymorphisms in the genes of the urokinase plasminogen activation system in relation to colorectal cancer. Ann. Oncol. 18: 1990-1994 (2007). *

• Fowell AJ, Thomas PW, Surgenor SL, Snook JA. The epidemiology of coeliac disease in East Dorset 1993-2002: an assessment of the 'coeliac iceberg', and preliminary evidence of case clustering. QJM 99: 453-460 (2006). *

• Foweraker J. Recent advances in the microbiology of respiratory tract infection in cystic fibrosis. Br. Med. Bull. 89: 93-110 (2009). *

• Fox JG, Lee A. The role of Helicobacter species in newly recognized gastrointestinal tract diseases of animals. Lab. Anim. Sci. 47: 222-255 (1997).

• Fox RI. Sjogren's syndrome. Curr. Opin. Rheumatol. 7: 409-416 (1995).

• Fox RI. Epidemiology, pathogenesis, animal models, and treatment of Sjogren's syndrome. Curr. Opin. Rheumatol. 6: 501-508 (1994).

• Fradet V, Cheng I, Casey G, Witte JS. Dietary omega-3 fatty acids, cyclooxygenase-2 genetic variation, and aggressive prostate cancer risk. Clin. Cancer Res. 15: 2559-2566 (2009). *

• Franchini M, Capra F, Nicolini N, Veneri D, Manzato F, Baudo F, Lippi G. Drug-induced anti-factor VIII antibodies: a systematic review. Med. Sci. Monit. 13: RA55-RA61 (2007). *

• Franco J, Saeian K. Biliary tract inflammatory disorders: primary sclerosing cholangitis and primary biliary cirrhosis. Curr. Gastroenterol. Rep. 1: 95-101 (1999).

• Franks PW, Ekelund U, Brage S, Luan J, Schafer AJ, O'Rahilly S, Barroso I, Wareham NJ. PPARGC1A coding variation may initiate impaired NEFA clearance during glucose challenge. Diabetologia 50: 569-573 (2007). *

• Franks PW, Jablonski KA, Delahanty L, Hanson RL, Kahn SE, Altshuler D, Knowler WC, Florez JC; Diabetes Prevention Program Research Group. The Pro12Ala variant at the peroxisome proliferator-activated receptor gamma gene and change in obesity-related traits in the Diabetes Prevention Program. Diabetologia 50: 2451-2460 (2007). *

• Fraser A, Thinggaard M, Christensen K, Lawlor DA. Alanine aminotransferase, gamma-glutamyltransferase (GGT) and all-cause mortality: results from a population-based Danish twins study alanine aminotransferase, GGT and mortality in elderly twins. Liver Int. 29: 1494-1499 (2009). *

• Freedman ND, Everhart JE, Lindsay KL, Ghany MG, Curto TM, Shiffman ML, Lee WM, Lok AS, Di Bisceglie AM, Bonkovsky HL, Hoefs JC, Dienstag JL, Morishima C, Abnet CC, Sinha R; HALT-C Trial Group. Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C. Hepatology 50: 1360-1369 (2009).

• Freimer N, Sabatti C. The use of pedigree, sib-pair and association studies of common diseases for genetic mapping and epidemiology. Nat. Genet. 36: 1045-1051 (2004). *

• Frey UH, Alakus H, Wohlschlaeger J, Schmitz KJ, Winde G, van Calker HG, Jockel KH, Siffert W, Schmid KW. GNAS1 T393C polymorphism and survival in patients with sporadic colorectal cancer. Clin. Cancer Res. 11: 5071-5077 (2005). *

• Friedrichs F, Henckaerts L, Vermeire S, Kucharzik T, Seehafer T, Moller-Krull M, Bornberg-Bauer E, Stoll M, Weiner J 3rd. The Crohn's disease susceptibility gene DLG5 as a member of the CARD interaction network. J. Mol. Med. 86: 423-432 (2008). *

• Friedrichs F, Stoll M. Role of discs large homolog 5. World J. Gastroenterol. 12: 3651-3656 (2006). *

• Frieling T. Functional and inflammatory bowel disorders. Med. Klin. (Munich) 101 Suppl. 1: 139-142 (2006).

• Fries W. Inflammatory bowel disease-associated spondyloarthropathies. World J. Gastroenterol. 15: 2441-2442 (2009). *

• Fries W, Costa S, Costantino G, Familiari L. Clinical practice in the management of ulcerative colitis - an Italian survey. Dig. Liver Dis. 40 Suppl. 2: S214-S219 (2008).

• Frisch M, Pedersen BV, Andersson RE. Appendicitis, mesenteric lymphadenitis, and subsequent risk of ulcerative colitis: cohort studies in Sweden and Denmark. BMJ 338: b716 (2009). *

• Frisch M, Rostgaard C. Appendectomy and ulcerative colitis. Epidemiology 16: 131-132 (2005).

• Fukumoto S, Yamauchi N, Moriguchi H, Hippo Y, Watanabe A, Shibahara J, Taniguchi H, Ishikawa S, Ito H, Yamamoto S, Iwanari H, Hironaka M, Ishikawa Y, Niki T, Sohara Y, Kodama T, Nishimura M, Fukayama M, Dosaka-Akita H, Aburatani H. Overexpression of the aldo-keto reductase family protein AKR1B10 is highly correlated with smokers' non-small cell lung carcinomas. Clin. Cancer Res. 11: 1776-1785 (2005). *

• Gabriel SE, Michaud K. Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases. Arthritis Res. Ther. 11: 229 (2009). *

• Gadalla SM, Amr S, Langenberg P, Baumgarten M, Davidson WF, Schairer C, Engels EA, Pfeiffer RM, Goedert JJ. Breast cancer risk in elderly women with systemic autoimmune rheumatic diseases: a population-based case-control study. Br. J. Cancer 100: 817-821 (2009). *

• Gadi VK. Fetal microchimerism and cancer. Cancer Lett. 276: 8-13 (2009).

• Gajperia C, Barbiere J, Greenberg D, Wright K, Lyratzopoulos G. Recent incidence trends and socio-demographic features of oesophageal and gastric cancer types in an English region. Aliment. Pharmacol. Ther. 30: 873-880 (2009). *

• Galanti MR, Cnattingius S, Granath F, Ekbom-Schnell A, Ekbom A. Smoking and environmental iodine as risk factors for thyroiditis among parous women. Eur. J. Epidemiol. 22: 467-472 (2007). *

• Gale CR, Marriott LD, Martyn CN, Limond J, Inskip HM, Godfrey KM, Law CM, Cooper C, West C, Robinson SM; for the Southampton Women’s Survey Study Group. Breastfeeding, the use of docosahexaenoic acid-fortified formulas in infancy and neuropsychological function in childhood. Arch. Dis. Child. Feb 4 [Epub ahead of print] (2010).

• Gale EA. A missing link in the hygiene hypothesis? Diabetologia 45: 588-594 (2002). *

• Galvani AP, Novembre J. The evolutionary history of the CCR5-Delta32 HIV-resistance mutation. Microbes Infect. 7: 302-309 (2005). *

• Gandini S, Raimondi S, Gnagnarella P, Dore JF, Maisonneuve P, Testori A. Vitamin D and skin cancer: a meta-analysis. Eur. J. Cancer 45: 634-641 (2009). *

• Ganry O, Lapotre-Ledoux B, Fardellone P, Dubreuil A. Bone mass density, subsequent risk of colon cancer and survival in postmenopausal women. Eur. J. Epidemiol. 23: 467-473 (2008).

• Gao C, Li Z, Ding J, Wang J, Hu X, Liu T, Xu T, Li H. Study on the relations between HLA-DRB 1 alleles and Helicobacter pylori infection. Zhonghua Liu Xing Bing Xue Za Zhi 21: 417-419 (2000).

• Gao CM, Tang JH, Cao HX, Ding JH, Wu JZ, Wang J, Liu YT, Li SP, Su P, Matsuo K, Takezaki T, Tajima K. MTHFR polymorphisms, dietary folate intake and breast cancer risk in Chinese women. J. Hum. Genet. 54: 414-418 (2009).

• Gao L, Nieters A, Brenner H. More statistical analysis is needed for the meta-analysis of genetic association studies: authors' reply. Aliment. Pharmacol. Ther. 29: 144 (2009). *

• Gao QJ, Liu DW, Zhang SY, Jia M, Wang LM, Wu LH, Wang SY, Tong LX. Polymorphisms of some cytokines and chronic hepatitis B and C virus infection. World J. Gastroenterol. 15: 5610-5619 (2009). *

• Gao X, Starmer J, Martin ER. A multiple testing correction method for genetic association studies using correlated single nucleotide polymorphisms. Genet. Epidemiol. 32: 361-369 (2008).

• Gao Y, Kristinsson SY, Goldin LR, Bjorkholm M, Caporaso NE, Landgren O. Increased risk for non-Hodgkin lymphoma in individuals with celiac disease and a potential familial association. Gastroenterology 136: 91-98 (2009). *

• Gao Y, Linet MS, Gridley G, Mellemkjaer L, Hemminki K, Goldin LR, Landgren O. Shared susceptibility for celiac disease and inflammatory bowel disease? Scand. J. Gastroenterol. 43: 1279-1280 (2008). *

• Garcia D, Angel B, Carrasco E, Albala C, Santos JL, Perez-Bravo F. VDR polymorphisms influence the immune response in type 1 diabetic children from Santiago, Chile. Diabetes Res. Clin. Pract. 77: 134-140 (2007).

• Garcia DF, Hiatt PW, Jewell A, Schoonover SL, Cron SG, Riggs M, Grace S, Oermann CM, Piedra PA. Human metapneumovirus and respiratory syncytial virus infections in older children with cystic fibrosis. Pediatr. Pulmonol. 42: 66-74 (2007). *

• Garcia-Closas M, Malats N, Real FX, Yeager M, Welch R, Silverman D, Kogevinas M, Dosemeci M, Figueroa J, Chatterjee N, Tardon A, Serra C, Carrato A, Garcia-Closas R, Murta-Nascimento C, Rothman N, Chanock SJ. Large-scale evaluation of candidate genes identifies associations between VEGF polymorphisms and bladder cancer risk. PLoS Genet. 3: e29 (2007). *

• Garcia-Diez A, Foraster CF, Sebastian FV, Tudela LL, Llach XB, Fernandez GS. What characterizes the severity of psoriasis? Results from an epidemiological study of over 3,300 patients in the Iberian region. Dermatology 216: 137-151 (2008).

• Gardener H, Munger K, Chitnis T, Spiegelman D, Ascherio A. The relationship between handedness and risk of multiple sclerosis. Mult. Scler. 15: 587-592 (2009). *

• Gardner MS, Rowland MD, Siu AY, Bundy JL, Wagener DK, Stephenson JL. Comprehensive defensin assay for saliva. Anal. Chem. 81: 557-566 (2009). *

• Gargano JW, Holzman C, Senagore P, Thorsen P, Skogstrand K, Hougaard DM, Rahbar MH, Chung H. Mid-pregnancy circulating cytokine levels, histologic chorioamnionitis and spontaneous preterm birth. J. Reprod. Immunol. 79: 100-110 (2008). *

• Garner CP, Ding YC, Steele L, Book L, Leiferman K, Zone JJ, Neuhausen SL. Genome-wide linkage analysis of 160 North American families with celiac disease. Genes Immun. 8: 108-114 (2007). *

• Garner CP, Murray JA, Ding YC, Tien Z, van Heel DA, Neuhausen SL. Replication of celiac disease UK genome-wide association study results in a US population. Hum. Mol. Genet. 18: 4219-4225 (2009).

• Garrido A, Martinez M, Ortega J, Lobato A, Rodriguez M, Guerrero F. Epidemiology of chronic inflammatory bowel disease in the Northern area of Huelva. Rev. Esp. Enferm. Dig. 96: 687-694 (2004).

• Gaseitsiwe S, Valentini D, Mahdavifar S, Reilly M, Ehrnst A, Maeurer M. Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501 and DRB1*0401. Clin. Vaccine Immunol. Oct 28 [Epub ahead of print] (2009). *

• Gast A, Bermejo JL, Flohr T, Stanulla M, Burwinkel B, Schrappe M, Bartram CR, Hemminki K, Kumar R. Folate metabolic gene polymorphisms and childhood acute lymphoblastic leukemia: a case-control study. Leukemia 21: 320-325 (2007).

• Gathany AH, Hartge P, Davis S, Cerhan JR, Severson RK, Cozen W, Rothman N, Chanock SJ, Wang SS. Relationship between interferon regulatory factor 4 genetic polymorphisms, measures of sun sensitivity and risk for non-Hodgkin lymphoma. Cancer Causes Control Apr 28 [Epub ahead of print] (2009). *

• Gaubitz M. Epidemiology of connective tissue disorders. Rheumatology (Oxford) 45 Suppl. 3: iii3-iii4 (2006). *

• Gaudet MM, Chanock S, Dunning A, Driver K, Brinton LA, Lissowska J, Peplonska B, Pharoah P, Garcia-Closas M. HSD17B1 genetic variants and hormone receptor-defined breast cancer. Cancer Epidemiol. Biomarkers Prev. 17: 2766-2772 (2008). *

• Gaudet MM, Gammon MD, Bensen JT, Sagiv SK, Shantakumar S, Teitelbaum SL, Eng SM, Neugut AI, Santella RM. Genetic variation of TP53, polycyclic aromatic hydrocarbon-related exposures, and breast cancer risk among women on Long Island, New York. Breast Cancer Res. Treat. 108: 93-99 (2008).

• Gause A, Schnabel A. Rheumatology 2003-part I: research news concerning pathogenesis, epidemiology, diagnosis, and therapy of chronic inflammatory joint diseases. Med. Klin. (Munich) 98: 523-533 (2003).

• Gearry RB, Richardson A, Frampton CM, Collett JA, Burt MJ, Chapman BA, Barclay ML. High incidence of Crohn's disease in Canterbury, New Zealand: results of an epidemiologic study. Inflamm. Bowel Dis. 12: 936-943 (2006). *

• Geenes V, Williamson C. Intrahepatic cholestasis of pregnancy. World J. Gastroenterol. 15: 2049-2066 (2009). *

• Gehmert S, Velapatino B, Herrera P, Balqui J, Santivanez L, Cok J, Vargas G, Combe J, Passaro DJ, Wen S, Meyer F, Berg DE, Gilman RH. Interleukin-1 beta single-nucleotide polymorphism's C allele is associated with elevated risk of gastric cancer in Helicobacter pylori-infected Peruvians. Am. J. Trop. Med. Hyg. 81: 804-810 (2009).

• Gelfand JM, Dommasch ED, Shin DB, Azfar RS, Kurd SK, Wang X, Troxel AB. The risk of stroke in patients with psoriasis. J. Invest. Dermatol. 129: 2411-2418 (2009). *

• Gelfand JM, Gladman DD, Mease PJ, Smith N, Margolis DJ, Nijsten T, Stern RS, Feldman SR, Rolstad T. Epidemiology of psoriatic arthritis in the population of the United States. J. Am. Acad. Dermatol. 53: 573 (2005).

• Gelfand JM, Kimball AB, Mostow EN, Chiou CF, Patel V, Xia HA, Freundlich B, Stevens SR. Patient-reported outcomes and health-care resource utilization in patients with psoriasis treated with etanercept: continuous versus interrupted treatment. Value Health 11: 400-407 (2008).

• Gelfand JM, Shin DB, Neimann AL, Wang X, Margolis DJ, Troxel AB. The risk of lymphoma in patients with psoriasis. J. Invest. Dermatol. 126: 2194-2201 (2006). *

• Geller DE, Rubin BK. Respiratory care and cystic fibrosis. Respir. Care 54: 796-800 (2009).

• Gensch K, Gudowius S, Niehues T, Kuhn A. Connective tissue diseases in childhood. Hautarzt. 56: 925-936 (2005).

• George JN. The thrombotic thrombocytopenic purpura and hemolytic uremic syndromes: overview of pathogenesis (experience of the Oklahoma TTP-HUS Registry, 1989-2007). Kidney Int. Suppl. 112: S8-S10 (2009).

• George JN. The thrombotic thrombocytopenic purpura and hemolytic uremic syndromes: evaluation, management, and long-term outcomes experience of the Oklahoma TTP-HUS Registry, 1989-2007. Kidney Int. Suppl. 112: S52-S54 (2009).

• Gerding DN, Johnson S, Peterson LR, Mulligan ME, Silva J Jr. Clostridium difficile-associated diarrhea and colitis. Infect. Control Hosp. Epidemiol. 16: 459-477 (1995).

• Gerhardus A, Schleberger H, Schlegelberger B, Gadzicki D. Diagnostic accuracy of methods for the detection of BRCA1 and BRCA2 mutations: a systematic review. Eur. J. Hum. Genet. 15: 619-627 (2007). *

• Gerner EW, Meyskens FL Jr. Combination chemoprevention for colon cancer targeting polyamine synthesis and inflammation. Clin. Cancer Res. 15: 758-761 (2009). *

• Gershwin ME. Primary biliary cirrhosis: from induction through destruction. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 39-40 (2004). *

• Gershwin ME, Selmi C, Worman HJ, Gold EB, Watnik M, Utts J, Lindor KD, Kaplan MM, Vierling JM, USA PBC Epidemiology Group. Risk factors and comorbidities in primary biliary cirrhosis: a controlled interview-based study of 1032 patients. Hepatology 42: 1194-1202 (2005). *

• Ghali P, Lindor KD. Hepatotoxicity of drugs used for treatment of obesity and its comorbidities. Semin. Liver Dis. 24: 389-397 (2004).

• Gheorghe C, Pascu O, Gheorghe L, Iacob R, Dumitru E, Tantau M, Vadan R, Goldis A, Balan G, Iacob S, Dobru D, Saftoiu A. Epidemiology of inflammatory bowel disease in adults who refer to gastroenterology care in Romania: a multicentre study. Eur. J. Gastroenterol. Hepatol. 16: 1153-1159 (2004).

• Giannini S, Martes C. Anemia in inflammatory bowel disease. Minerva Gastroenterol. Dietol. 52: 275-291 (2006).

• Gibbons LJ, Hyrich KL. Biologic therapy for rheumatoid arthritis: clinical efficacy and predictors of response. BioDrugs 23: 111-124 (2009).

• Gibbons LJ, Thomson W, Zeggini E, Worthington J, Barton A, Eyre S, Donn R, Hinks A. The type 1 diabetes susceptibility gene SUMO4 at IDDM5 is not associated with susceptibility to rheumatoid arthritis or juvenile idiopathic arthritis. Rheumatology (Oxford) 44: 1390-1393 (2005). *

• Gibson A, Stamp LK, Chapman PT, O'Donnell JL. The epidemiology of Wegener's granulomatosis and microscopic polyangiitis in a Southern Hemisphere region. Rheumatology (Oxford) 45: 624-628 (2006). *

• Gibson PR. Overview of inflammatory bowel disease in Australia in the last 50 years. J. Gastroenterol. Hepatol. 24 Suppl. 3: S63-S68 (2009). *

• Gieger C, Geistlinger L, Altmaier E, Hrabe de Angelis M, Kronenberg F, Meitinger T, Mewes HW, Wichmann HE, Weinberger KM, Adamski J, Illig T, Suhre K. Genetics meets metabolomics: a genome-wide association study of metabolite profiles in human serum. PLoS Genet. 4: e1000282 (2008). *

• Giercksky KE. COX-2 inhibition and prevention of cancer. Best Pract. Res. Clin. Gastroenterol. 15: 821-833 (2001). *

• Gilat T, Rozen P. Epidemiology of Crohn's disease and ulcerative colitis: etiologic implications. Isr. J. Med. Sci. 15: 305-308 (1979).

• Giles JT, Fernandes V, Lima JA, Bathon JM. Myocardial dysfunction in rheumatoid arthritis: epidemiology and pathogenesis. Arthritis Res. Ther. 7: 195-207 (2005). *

• Gillespie EE, Kotsanas D, Stuart RL. Microbiological monitoring of endoscopes: 5-year review. J. Gastroenterol. Hepatol. 23: 1069-1074 (2008). *

• Giovannucci E. The epidemiology of vitamin D and colorectal cancer: recent findings. Curr. Opin. Gastroenterol. 22: 24-29 (2006).

• Gladman DD, Antoni C, Mease P, Clegg DO, Nash P. Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann. Rheum. Dis. 64 Suppl. 2: ii14-ii17 (2005). *

• Gogia S, Sachdev HS. Neonatal vitamin A supplementation for prevention of mortality and morbidity in infancy: systematic review of randomised controlled trials. BMJ 338: b919 (2009).

• Goh DL, Zhou Y, Chong SS, Ngiam NS, Goh DY. Novel CFTR gene mutation in a patient with CBAVD. J. Cyst. Fibros. 6: 423-425 (2007).

• Goh K, Xiao SD. Inflammatory bowel disease: a survey of the epidemiology in Asia. J. Dig. Dis. 10: 1-6 (2009). *

• Gohlke H, Ferrari U, Koczwara K, Bonifacio E, Illig T, Ziegler AG. SLC30A8 (ZnT8) polymorphism is associated with young age at type 1 diabetes onset. Rev. Diabet. Stud. 5: 25-27 (2008). *

• Gold BD. Epidemiology and management of gastro-oesophageal reflux in children. Aliment. Pharmacol. Ther. 19 Suppl. 1: 22-27 (2004).

• Goldacre MJ. Demography of aging and the epidemiology of gastrointestinal disorders in the elderly. Best Pract. Res. Clin. Gastroenterol. 23: 793-804 (2009).

• Goldacre MJ, Duncan M, Cook-Mozaffari P, Griffith M, Travis S. Inflammatory bowel disease, peptic ulcer and diverticular disease as certified causes of death in an English population 1979-2003. Eur. J. Gastroenterol. Hepatol. 20: 96-103 (2008).

• Goldacre MJ, Wotton CJ, Seagroatt V, Yeates D. Immune-related disease before and after vasectomy: an epidemiological database study. Hum. Reprod. 22: 1273-1278 (2007). *

• Goldacre MJ, Wotton CJ, Yeates D, Seagroatt V, Collier J. Liver cirrhosis, other liver diseases, pancreatitis and subsequent cancer: record linkage study. Eur. J. Gastroenterol. Hepatol. 20: 384-392 (2008).

• Goldacre MJ, Wotton CJ, Yeates D, Seagroatt V, Jewell D. Cancer in patients with ulcerative colitis, Crohn's disease and coeliac disease: record linkage study. Eur. J. Gastroenterol. Hepatol. 20: 297-304 (2008).

• Goldacre MJ, Wotton CJ, Yeates DG. Associations between infectious mononucleosis and cancer: record-linkage studies. Epidemiol. Infect. 137: 672-680 (2009).

• Goldani LZ, Zavascki AP, Maia AL. Fungal thyroiditis: an overview. Mycopathologia 161: 129-139 (2006). *

• Goldin LR, Landgren O. Autoimmunity and lymphomagenesis. Int. J. Cancer 124: 1497-1502 (2009). *

• Golding J, Steer C, Emmett P, Davis JM, Hibbeln JR. High levels of depressive symptoms in pregnancy with low omega-3 fatty acid intake from fish. Epidemiology 20: 598-603 (2009).

• Golembesky AK, Gammon MD, North KE, Bensen JT, Schroeder JC, Teitelbaum SL, Neugut AI, Santella RM. Peroxisome proliferator-activated receptor-alpha (PPARA) genetic polymorphisms and breast cancer risk: a Long Island ancillary study. Carcinogenesis 29: 1944-1949 (2008). *

• Gomaa AI, Khan SA, Toledano MB, Waked I, Taylor-Robinson SD. Hepatocellular carcinoma: epidemiology, risk factors and pathogenesis. World J. Gastroenterol. 14: 4300-4308 (2008). *

• Gomes ER, Demoly P. Epidemiology of hypersensitivity drug reactions. Curr. Opin. Allergy Clin. Immunol. 5: 309-316 (2005).

• Gomollon F, Gisbert JP, Gassull MA. Crohnology: a tale of time and times and inflammatory bowel diseases. World J. Gastroenterol. 14: 5489-5490 (2008). *

• Gong Y, Gluud C. Colchicine for primary biliary cirrhosis: a Cochrane hepato-biliary group systematic review of randomized clinical trials. Am. J. Gastroenterol. 100: 1-10 (2005). *

• Gong Y, Huang Z, Christensen E, Gluud C. Ursodeoxycholic acid for patients with primary biliary cirrhosis: an updated systematic review and meta-analysis of randomized clinical trials using Bayesian approach as sensitivity analyses. Am. J. Gastroenterol. 102: 1799-1807 (2007). *

• Gong Z, Holly EA, Wang F, Chan JM, Bracci PM. Intake of fatty acids and antioxidants and pancreatic cancer in a large population-based case-control study in the San Francisco Bay Area. Int. J. Cancer Jan 26 [Epub ahead of print] (2010). *

• Gong Z, Xie D, Deng Z, Bostick RM, Muga SJ, Hurley TG, Hebert JR. The PPARgamma Pro12Ala polymorphism and risk for incident sporadic colorectal adenomas. Carcinogenesis 26: 579-585 (2005). *

• Gonzalez E, Dhanda R, Bamshad M, Mummidi S, Geevarghese R, Catano G, Anderson SA, Walter EA, Stephan KT, Hammer MF, Mangano A, Sen L, Clark RA, Ahuja SS, Dolan MJ, Ahuja SK. Global survey of genetic variation in CCR5, RANTES, and MIP-1alpha: impact on the epidemiology of the HIV-1 pandemic. Proc. Natl. Acad. Sci. U.S.A. 98: 5199-5204 (2001). *

• Gonzalez-Quintela A, Campos J, Quinteiro C, Gude F. Liver enzyme levels in relation to a common polymorphism in the CD14 promoter gene. Eur. J. Gastroenterol. Hepatol. 19: 182-183 (2007).

• Gonzalez-Zuloeta Ladd AM, Arias Vasquez A, Witteman J, Uitterlinden AG, Coebergh JW, Hofman A, Stricker BH, van Duijn CM. Interleukin 6 G-174 C polymorphism and breast cancer risk. Eur. J. Epidemiol. 21: 373-376 (2006). *

• Goodin DS. The causal cascade to multiple sclerosis: a model for MS pathogenesis. PLoS ONE 4: e4565 (2009). *

• Gordon FD. Primary sclerosing cholangitis. Surg. Clin. North Am. 88: 1385-1407 (2008).

• Gordon MA. Salmonella infections in immunocompromised adults. J. Infect. 56: 413-422 (2008).

• Gores GJ, Baskin-Bey ES, Baron TH, Alberts SR. Treatment endpoints for advanced cholangiocarcinoma. Nat. Clin. Pract. Gastroenterol. Hepatol. 1: 4-5 (2004). *

• Goss CH, Burns JL. Exacerbations in cystic fibrosis. 1: Epidemiology and pathogenesis. Thorax 62: 360-367 (2007). *

• Gotua M, Lomidze N, Dolidze N, Gotua T. IgE-mediated food hypersensitivity disorders. Georgian Med. News 157: 39-44 (2008).

• Goyal S, Gupta P, Ryan CM, Kazlas M, Noviski N, Sheridan RL. Toxic epidermal necrolysis in children: medical, surgical, and ophthalmologic considerations. J. Burn Care Res. 30: 437-449 (2009).

• Gradel KO, Nielsen HL, Schonheyder HC, Ejlertsen T, Kristensen B, Nielsen H. Increased short and long term risk of inflammatory bowel disease after Salmonella or Campylobacter gastroenteritis. Gastroenterology 137: 495-501 (2009). *

• Graindorge A, Menard A, Neto M, Bouvet C, Miollan R, Gaillard S, de Montclos H, Laurent F, Cournoyer B. Epidemiology and molecular characterization of a clone of Burkholderia cenocepacia responsible for nosocomial pulmonary tract infections in a French intensive care unit. Diagn. Microbiol. Infect. Dis. 66: 29-40 (2010).

• Grainge MJ, West J, Card TR. Venous thromboembolism during active disease and remission in inflammatory bowel disease: a cohort study. Lancet Feb 8 [Epub ahead of print] (2010). *

• Grainge MJ, West J, Solaymani-Dodaran M, Aithal GP, Card TR. The antecedents of biliary cancer: a primary care case-control study in the United Kingdom. Br. J. Cancer 100: 178-180 (2009). *

• Grant WB. Epidemiology of disease risks in relation to vitamin D insufficiency. Prog. Biophys. Mol. Biol. 92: 65-79 (2006). *

• Grassi M, Raffa S, Damiani VC, Fontana M. Current orientation in medical management of ulcerative colitis. Clin. Ter. 146: 327-341 (1995).

• Gravholt CH. Clinical practice in Turner syndrome. Nat. Clin. Pract. Endocrinol. Metab. 1: 41-52 (2005). *

• Grawal AA, Whorwell PJ. Review article: abdominal bloating and distension in functional gastrointestinal disorders: epidemiology and exploration of possible mechanisms. Aliment. Pharmacol. Ther. 27: 2-10 (2008). *

• Gray-McGuire C, Sinha R, Iyengar S, Millard C, Rybicki BA, Elston RC, Iannuzzi MC; SAGA Study Consortium. Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5. Hum. Genet. 120: 420-430 (2006). *

• Grebely J, Thomas DL, Dore GJ. HCV reinfection studies and the door to vaccine development. J. Hepatol. 51: 628-631 (2009).

• Green C, Elliott L, Beaudoin C, Bernstein CN. A population-based ecologic study of inflammatory bowel disease: searching for etiologic clues. Am. J. Epidemiol. 164: 615-623 (2006). *

• Green D, Carson K, Leonard A, Davis JE, Rosenstein B, Zeitlin P, Mogayzel P Jr. Current treatment recommendations for correcting vitamin D deficiency in pediatric patients with cystic fibrosis are inadequate. J. Pediatr. 153: 554-559 (2008). *

• Greenlee H, Kwan ML, Ergas IJ, Sherman KJ, Krathwohl SE, Bonnell C, Lee MM, Kushi LH. Complementary and alternative therapy use before and after breast cancer diagnosis: the Pathways study. Breast Cancer Res. Treat. 117: 653-665 (2009).

• Greenson JK, Huang SC, Herron C, Moreno V, Bonner JD, Tomsho LP, Ben-Izhak O, Cohen HI, Trougouboff P, Bejhar J, Sova Y, Pinchev M, Rennert G, Gruber SB. Pathologic predictors of microsatellite instability in colorectal cancer. Am. J. Surg. Pathol. 33: 126-133 (2009).

• Grignard E, Gueguen Y, Grison S, Lobaccaro JM, Gourmelon P, Souidi M. Contamination with depleted or enriched uranium differently affects steroidogenesis metabolism in rat. Int. J. Toxicol. 27: 323-328 (2008). *

• Grimaldi LM, Palmeri B, Salemi G, Giglia G, D'Amelio M, Grimaldi R, Vitello G, Ragonese P, Savettieri G. High prevalence and fast rising incidence of multiple sclerosis in Caltanissetta, Sicily, Southern Italy. Neuroepidemiology 28: 28-32 (2006).

• Grjibovski AM, Olsen AO, Magnus P, Harris JR. Psoriasis in Norwegian twins: contribution of genetic and environmental effects. J. Eur. Acad. Dermatol. Venereol. 21: 1337-1343 (2007). *

• Gross RG, Odin JA. Recent advances in the epidemiology of primary biliary cirrhosis. Clin. Liver Dis. 12: 289-303 (2008).

• Grossman AB, Baldassano RN. Specific considerations in the treatment of pediatric inflammatory bowel disease. Expert Rev. Gastroenterol. Hepatol. 2: 105-124 (2008).

• Gruber SB. New developments in Lynch syndrome (hereditary nonpolyposis colorectal cancer) and mismatch repair gene testing. Gastroenterology 130: 577-587 (2006). *

• Grulich AE, Vajdic CM. The epidemiology of non-Hodgkin lymphoma. Pathology 37: 409-419 (2005).

• Grulich AE, Vajdic CM, Cozen W. Altered immunity as a risk factor for non-Hodgkin lymphoma. Cancer Epidemiol. Biomarkers Prev. 16: 405-408 (2007). *

• Gu F, Monsees G, Kraft P. Exhaustive screens for disease susceptibility loci incorporating statistical interaction of genotypes: a comparison of likelihood-ratio-based and Akaike and Bayesian information criteria-based methods. BMC Proc. 1 Suppl. 1: S25 (2007). *

• Guarner F, Casellas F, Borruel N, Antolín M, Videla S, Vilaseca J, Malagelada JR. Role of microecology in chronic inflammatory bowel diseases. Eur. J. Clin. Nutr. 56 Suppl. 4: S34-S38 (2002). *

• Guarner F, Malagelada JR. Role of bacteria in experimental colitis. Best Pract. Res. Clin. Gastroenterol. 17: 793-804 (2003).

• Gudjonsson JE, Elder JT. Psoriasis: epidemiology. Clin. Dermatol. 25: 535-546 (2007).

• Guglielmi L, Guglielmi P, Demoly P. Drug hypersensitivity: epidemiology and risk factors. Curr. Pharm. Des. 12: 3309-3312 (2006).

• Guibal F, Baran R, Duhard E, Feuilhade de Chauvin M. Epidemiology and management of onychomycosis in private dermatological practice in France. Ann. Dermatol. Venereol. 135: 561-566 (2008).

• Guillen M, Corella D, Cabello ML, Gonzalez JI, Sabater A, Chaves JF, Hernandez-Yago J. Identification of novel SLC3A1 gene mutations in Spanish cystinuria families and association with clinical phenotypes. Clin. Genet. 67: 240-251 (2004). *

• Guillet G, Strobel M, Pradinaud R. Brazilian pemphigus in a child in French Guyana. Discussion on the clinical polymorphism and epidemiology of the disease. Ann. Dermatol. Venereol. 111: 1087-1092 (1984).

• Guinot C, Latreille J, Perrussel M, Doss N, Dubertret L; French Psoriasis Group. Psoriasis: characterization of six different clinical phenotypes. Exp. Dermatol. 18: 712-719 (2009). *

• Gupta AK, Schoen RE. Aberrant crypt foci: are they intermediate endpoints of colon carcinogenesis in humans? Curr. Opin. Gastroenterol. 25: 59-65 (2009).

• Gupta G, Gelfand JM, Lewis JD. Increased risk of demyelinating diseases in patients with inflammatory bowel disease. Gastroenterology 129: 819-826 (2005). *

• Gupta G, Lautenbach E, Lewis JD. Incidence and risk factors for herpes zoster among patients with inflammatory bowel disease. Clin. Gastroenterol. Hepatol. 4: 1483-1490 (2006).

• Gurrin LC, Bertalli NA, Dalton GW, Osborne NJ, Constantine CC, McLaren CE, English DR, Gertig DM, Delatycki MB, Nicoll AJ, Southey MC, Hopper JL, Giles GG, Anderson GJ, Olynyk JK, Powell LW, Allen KJ. HFE C282Y/H63D compound heterozygotes are at low risk of hemochromatosis-related morbidity. Hepatology 50: 94-101 (2009).

• Haahr S, Hollsberg P. Multiple sclerosis is linked to Epstein-Barr virus infection. Rev. Med. Virol. 16: 297-310 (2006).

• Haber P, DeStefano F, Angulo FJ, Iskander J, Shadomy SV, Weintraub E, Chen RT. Guillain-Barre syndrome following influenza vaccination. JAMA 292: 2478-2481 (2004). *

• Haga HJ, Gjesdal CG, Koksvik HS, Skomsvoll JF, Irgens LM, Ostensen M. Pregnancy outcome in patients with primary Sjogren's syndrome. A case-control study. J. Rheumatol. 32: 1734-1736 (2005).

• Hagen EA, Lautenbach E, Olthoff K, Blumberg EA. Low prevalence of colonization with vancomycin-resistant Enterococcus in patients awaiting liver transplantation. Am. J. Transplant. 3: 902-905 (2003). *

• Hajeer AH, Dababneh A, Makki RF, Thomson W, Poulton K, Gonzalez-Gay MA, Garcia-Porrua C, Mattey DL, Ollier WE. Different gene loci within the HLA-DR and TNF regions are independently associated with susceptibility and severity in Spanish rheumatoid arthritis patients. Tissue Antigens 55: 319-325 (2000). *

• Halevy S. Acute generalized exanthematous pustulosis. Curr. Opin. Allergy Clin. Immunol. 9: 322-328 (2009).

• Hallas J, Gaist D, Sorensen HT. Does appendectomy reduce the risk of ulcerative colitis? Epidemiology 15: 173-178 (2004).

• Hallas J, Gaist D, Vach W, Sorensen HT. Appendicectomy has no beneficial effect on admission rates in patients with ulcerative colitis. Gut 53: 351-354 (2004). *

• Hallasm J, Gaist D, Sorensen HT. Appendectomy and ulcerative colitis. Epidemiology 16: 132-133 (2005).

• Halsey NA, Hyman SL; Conference Writing Panel. Measles-mumps-rubella vaccine and autistic spectrum disorder: report from the New Challenges in Childhood Immunizations Conference convened in Oak Brook, Illinois, June 12-13, 2000. Pediatrics 107: e84 (2001). *

• Hamer M, Steptoe A. Association between physical fitness, parasympathetic control, and proinflammatory responses to mental stress. Psychosom. Med. 69: 660-666 (2007).

• Han J, Colditz GA, Hunter DJ. Polymorphisms in the MTHFR and VDR genes and skin cancer risk. Carcinogenesis 28: 390-397 (2007). *

• Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm. Bowel Dis. 12 Suppl. 1: S3-S9 (2006). *

• Hanauer SB, Present DH, Wolf JL, Jones WK, Marts SA. The state of the art in the management of inflammatory bowel disease. Based on the proceedings of a roundtable held December 12-13, 2001. Clinician 20: 1-31 (2002). *

• Hancock DB, Eijgelsheim M, Wilk JB, Gharib SA, Loehr LR, Marciante KD, Franceschini N, van Durme YM, Chen TH, Barr RG, Schabath MB, Couper DJ, Brusselle GG, Psaty BM, van Duijn CM, Rotter JI, Uitterlinden AG, Hofman A, Punjabi NM, Rivadeneira F, et al. Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function. Nat. Genet. 42: 45-52 (2010). *

• Hancock L, Beckly J, Geremia A, Cooney R, Cummings F, Pathan S, Guo C, Warren BF, Mortensen N, Ahmad T, Jewell D. Clinical and molecular characteristics of isolated colonic Crohn's disease. Inflamm. Bowel Dis. 14: 1667-1677 (2008). *

• Hansen RD, Krath BN, Frederiksen K, Tjønneland A, Overvad K, Roswall N, Loft S, Dragsted LO, Vogel U, Raaschou-Nielsen O. GPX1 Pro(198)Leu polymorphism, erythrocyte GPX activity, interaction with alcohol consumption and smoking, and risk of colorectal cancer. Mutat. Res. 664: 13-19 (2009).

• Hanson RL, Knowler WC. Design and analysis of genetic association studies to finely map a locus identified by linkage analysis: assessment of the extent to which an association can account for the linkage. Ann. Hum. Genet. 72: 126-139 (2008). *

• Harding AH, Loos RJ, Luan J, O'Rahilly S, Wareham NJ, Barroso I. Polymorphisms in the gene encoding sterol regulatory element-binding factor-1c are associated with type 2 diabetes. Diabetologia 49: 2642-2648 (2006). *

• Harpaz N, Talbot IC. Colorectal cancer in idiopathic inflammatory bowel disease. Semin. Diagn. Pathol. 13: 339-357 (1996).

• Harrison P, Pointon JJ, Chapman K, Roddam A, Wordsworth BP. Interleukin-1 promoter region polymorphism role in rheumatoid arthritis: a meta-analysis of IL-1B-511A/G variant reveals association with rheumatoid arthritis. Rheumatology (Oxford) 47: 1768-1770 (2008). *

• Harrison SA. Non-alcoholic steatohepatitis. Preface. Clin. Liver Dis. 13: xiii-xiv (2009). *

• Harvald B. Genetic epidemiology of Greenland. Clin. Genet. 36: 364-367 (1989).

• Hassan B, Maxwell JR, Hyrich KL; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate, Barton A, Worthington J, Isaacs JD, Morgan AW, Wilson AG. Genotype at the sIL-6R A358C polymorphism does not influence response to anti-TNF therapy in patients with rheumatoid arthritis. Rheumatology (Oxford) 49: 43-47 (2010).

• Hassan MM, Spitz MR, Thomas MB, Curley SA, Patt YZ, Vauthey JN, Glover KY, Kaseb A, Lozano RD, El-Deeb AS, Nguyen NT, Wei SH, Chan W, Abbruzzese JL, Li D. The association of family history of liver cancer with hepatocellular carcinoma: a case-control study in the United States. J. Hepatol. 50: 334-341 (2009).

• Hatch EE, Nelson JW, Stahlhut RW, Webster TF. Association of endocrine disruptors and obesity: perspectives from epidemiological studies. Int. J. Androl. Jan 22 [Epub ahead of print] (2010).

• Haug K, Schrumpf E, Barstad S, Fluge G, Halvorsen JF. Epidemiology of ulcerative colitis in Western Norway. Scand. J. Gastroenterol. 23: 517-522 (1988).

• Haug U, Hundt S, Brenner H. Quantitative immunochemical fecal occult blood testing for colorectal adenoma detection: evaluation in the target population of screening and comparison with qualitative tests. Am. J. Gastroenterol. Dec 1 [Epub ahead of print] (2009). *

• Hay A. Controlling exposure to chemicals: a simple guide. Ann. N. Y. Acad. Sci. 1076: 790-799 (2006). *

• Hazra A, Fuchs CS, Chan AT, Giovannucci EL, Hunter DJ. Association of the TCF7L2 polymorphism with colorectal cancer and adenoma risk. Cancer Causes Control 19: 975-980 (2008). *

• Hazra A, Kraft P, Lazarus R, Chen C, Chanock SJ, Jacques P, Selhub J, Hunter DJ. Genome-wide significant predictors of metabolites in the one-carbon metabolism pathway. Hum. Mol. Genet. 18: 4677-4687 (2009).

• Hazra A, Kraft P, Selhub J, Giovannucci EL, Thomas G, Hoover RN, Chanock SJ, Hunter DJ. Common variants of FUT2 are associated with plasma vitamin B12 levels. Nat. Genet. 40: 1160-1162 (2008). *

• He K. Fish, long-chain omega-3 polyunsaturated fatty acids and prevention of cardiovascular disease - eat fish or take fish oil supplement? Prog. Cardiovasc. Dis. 52: 95-114 (2009).

• Heazlewood CK, Cook MC, Eri R, Price GR, Tauro SB, Taupin D, Thornton DJ, Png CW, Crockford TL, Cornall RJ, Adams R, Kato M, Nelms KA, Hong NA, Florin TH, Goodnow CC, McGuckin MA. Aberrant mucin assembly in mice causes endoplasmic reticulum stress and spontaneous inflammation resembling ulcerative colitis. PLoS Med. 5: e54 (2008). *

• Heid IM, Vollmert C, Kronenberg F, Huth C, Ankerst DP, Luchner A, Hinney A, Bronner G, Wichmann HE, Illig T, Doring A, Hebebrand J. Association of the MC4R V103I polymorphism with the metabolic syndrome: the KORA study. Obesity (Silver Spring) 16: 369-376 (2008). *

• Heiligenhaus A, Mingels A, Neudorf U, Ganser G. Juvenile idiopathic arthritis and uveitis: screening and anti-inflammatory therapy. Klin. Monatsbl. Augenheilkd. 220: 738-753 (2003).

• Heiligenhaus A, Niewerth M, Mingels A, Ganser G, Thon A, Pleyer U, Greiner K, Minden K. Epidemiology of uveitis in juvenile idiopathic arthritis from a national paediatric rheumatologic and ophthalmologic database. Klin. Monatsbl. Augenheilkd. 222: 993-1001 (2005).

• Heimpel H. Congenital dyserythropoietic anemias: epidemiology, clinical significance, and progress in understanding their pathogenesis. Ann. Hematol. 83: 613-621 (2004). *

• Hein DW. N-Acetyltransferase 2 genetic polymorphism: effects of carcinogen and haplotype on urinary bladder cancer risk. Oncogene 25: 1649-1658 (2006). *

• Hemminki K, Bermejo JL, Hemminki K, Forsti A. Genetics of inflammatory bowel disease: population aspects. Gastroenterology 134: 2190-2191 (2008). *

• Hemminki K, Forsti A, Bermejo JL. Gene-environment interactions in cancer: do they exist? Ann. N. Y. Acad. Sci. 1076: 137-148 (2006). *

• Hemminki K, Forsti A, Lorenzo Bermejo J. Etiologic impact of known cancer susceptibility genes. Mutat. Res. 658: 42-54 (2008).

• Hemminki K, Forsti A, Lorenzo Bermejo J. Surveying the genomic landscape of colorectal cancer. Am. J. Gastroenterol. 104: 789-790 (2009).

• Hemminki K, Li X, Johansson SE, Sundquist K, Sundquist J. Re: "Familial risk of multiple sclerosis: a nationwide cohort study". Am. J. Epidemiol. 163: 873-874 (2006). *

• Hemminki K, Li X, Sundquist J, Hillert J, Sundquist K. Risk for multiple sclerosis in relatives and spouses of patients diagnosed with autoimmune and related conditions. Neurogenetics 10: 5-11 (2009).

• Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in ulcerative colitis patients. Int. J. Cancer 123: 1417-1421 (2008). *

• Hemminki K, Li X, Sundquist J, Sundquist K. Familial risks for amyotrophic lateral sclerosis and autoimmune diseases. Neurogenetics 10: 111-116 (2009).

• Hemminki K, Li X, Sundquist J, Sundquist K. Cancer risks in Crohn disease patients. Ann. Oncol. 20: 574-580 (2009).

• Hemminki K, Li X, Sundquist J, Sundquist K. Familial association between type 1 diabetes and other autoimmune and related diseases. Diabetologia 52: 1820-1828 (2009). *

• Hemminki K, Li X, Sundquist J, Sundquist K. The epidemiology of Graves' disease: evidence of a genetic and an environmental contribution. J. Autoimmun. Dec 26 [Epub ahead of print] (2009).

• Hemminki K, Li X, Sundquist J, Sundquist K. Subsequent autoimmune or related disease in asthma patients: clustering of diseases or medical care? Ann. Epidemiol. Dec 24 [Epub ahead of print] (2009).

• Hemminki K, Li X, Sundquist K, Sundquist J. Do inflammatory bowel disease and cancer share susceptibility: a family study. Inflamm. Bowel Dis. 14: 1167-1168 (2008). *

• Hemminki K, Li X, Sundquist K, Sundquist J. Familial association of inflammatory bowel diseases with other autoimmune and related diseases. Am. J. Gastroenterol. 105: 139-147 (2010). *

• Hemminki K, Shu X, Li X, Ji J, Sundquist J, Sundquist K. Familial risks for hospitalization with endocrine diseases. J. Clin. Endocrinol. Metab. 93: 4755-4758 (2008). *

• Hemminki K, Sundquist K, Li X. Familial risks for main neurological diseases in siblings based on hospitalizations in Sweden. Twin Res. Hum. Genet. 9: 580-586 (2006).

• Herbeck JT, Gottlieb GS, Winkler CA, Nelson GW, An P, Maust BS, Wong KG, Troyer JL, Goedert JJ, Kessing BD, Detels R, Wolinsky SM, Martinson J, Buchbinder S, Kirk GD, Jacobson LP, Margolick JB, Kaslow RA, O'Brien SJ, Mullins JI. Multistage genomewide association study identifies a locus at 1q41 associated with rate of HIV-1 disease progression to clinical AIDS. J. Infect. Dis. Dec 29 [Epub ahead of print] (2009). *

• Herfarth H. Therapy of IBD: bottom-up or top-down? Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, pp. 56-57 (2006). *

• Hernan MA, Alonso A, Hernandez-Diaz S. Tetanus vaccination and risk of multiple sclerosis: a systematic review. Neurology 67: 212-215 (2006).

• Hernan MA, Jick SS. Rejoinder on "hepatitis B vaccination and multiple sclerosis the jury is still out". Pharmacoepidemiol. Drug Saf. 16: 707-708 (2007).

• Hernan MA, Olek MJ, Ascherio A. Cigarette smoking and incidence of multiple sclerosis. Am. J. Epidemiol. 154: 69-74 (2001). *

• Hernan MA, Zhang SM, Lipworth L, Olek MJ, Ascherio A. Multiple sclerosis and age at infection with common viruses. Epidemiology 12: 301-306 (2001).

• Hernandez-Salazar A, de Leon-Rosales SP, Rangel-Frausto S, Criollo E, Archer-Dubon C, Orozco-Topete R. Epidemiology of adverse cutaneous drug reactions. A prospective study in hospitalized patients. Arch. Med. Res. 37: 899-902 (2006).

• Herold C, Steffens M, Brockschmidt FF, Baur MP, Becker T. INTERSNP: genome-wide interaction analysis guided by a priori information. Bioinformatics 25: 3275-3281 (2009). *

• Heude B, Petry CJ, Pembrey M, Dunger DB, Ong KK. The insulin gene variable number of tandem repeat: associations and interactions with childhood body fat mass and insulin secretion in normal children. J. Clin. Endocrinol. Metab. 91: 2770-2775 (2006). *

• Hickey PW, Sutton DA, Fothergill AW, Rinaldi MG, Wickes BL, Schmidt HJ, Walsh TJ. Trichosporon mycotoxinivorans: a novel respiratory pathogen in patients with cystic fibrosis. J. Clin. Microbiol. 47: 3091-3097 (2009). *

• Hider SL, Bruce IN, Silman AJ, Symmons DP. Defining response to disease modifying antirheumatic drugs in patients with rheumatoid arthritis. J. Rheumatol. 32: 6-10 (2005).

• Hider SL, Bruce IN, Thomson W. The pharmacogenetics of methotrexate. Rheumatology (Oxford) 46: 1520-1524 (2007). *

• Hildenbrand P, Craven DE, Jones R, Nemeskal P. Lyme neuroborreliosis: manifestations of a rapidly emerging zoonosis. AJNR Am. J. Neuroradiol. 30: 1079-1087 (2009). *

• Hill ID. Management of celiac disease in childhood and adolescence: unique challenges and strategies. Curr. Treat. Options Gastroenterol. 9: 399-408 (2006).

• Hinks A, Worthington J, Thomson W. The association of PTPN22 with rheumatoid arthritis and juvenile idiopathic arthritis. Rheumatology (Oxford) 45: 365-368 (2006). *

• Hintzpeter B, Mensink GB, Thierfelder W, Muller MJ, Scheidt-Nave C. Vitamin D status and health correlates among German adults. Eur. J. Clin. Nutr. 62: 1079-1089 (2008). *

• Hirono K, Kemmotsu Y, Wittkowski H, Foell D, Saito K, Ibuki K, Watanabe K, Watanabe S, Uese K, Kanegane H, Origasa H, Ichida F, Roth J, Miyawaki T, Saji T. Infliximab reduce the cytokine-mediated inflammation but does not suppress cellular infiltration of the vessel wall in refractory Kawasaki disease. Pediatr. Res. 65: 696-701 (2009).

• Hissaria P, Cai FZ, Ahern M, Smith M, Gillis D, Roberts-Thomson P. Wegener's granulomatosis: epidemiological and clinical features in a South Australian study. Intern. Med. J. 38: 776-780 (2008). *

• Ho P, Barton A, Worthington J. Genetic epidemiology of psoriatic arthritis. Mod. Rheumatol. 14: 91-100 (2004).

• Ho P, Worthington J, Bruce IN, Barton A. Investigation of association of the DLG5 gene with psoriatic arthritis. Ann. Rheum. Dis. 66: 273-274 (2007). *

• Hofer U, Speck RF. Disturbance of the gut-associated lymphoid tissue is associated with disease progression in chronic HIV infection. Semin. Immunopathol. 31: 257-266 (2009). *

• Hoffenberg EJ, Liu E. Celiac disease for the allergist: who and how to screen. Allergy Asthma Proc. 28: 20-24 (2007).

• Hoggart CJ, Clark TG, De Iorio M, Whittaker JC, Balding DJ. Genome-wide significance for dense SNP and resequencing data. Genet. Epidemiol. 32: 179-185 (2008). *

• Hold GL, Rabkin CS, Gammon MD, Berry SH, Smith MG, Lissowska J, Risch HA, Chow WH, Mowat NA, Vaughan TL, El-Omar EM. CD14-159C/T and TLR9-1237T/C polymorphisms are not associated with gastric cancer risk in Caucasian populations. Eur. J. Cancer Prev. 18: 117-119 (2009).

• Holick CN, Stanford JL, Kwon EM, Ostrander EA, Nejentsev S, Peters U. Comprehensive association analysis of the vitamin D pathway genes, VDR, CYP27B1, and CYP24A1, in prostate cancer. Cancer Epidemiol. Biomarkers Prev. 16: 1990-1999 (2007). *

• Hollegaard MV, Bidwell JL. Cytokine gene polymorphism in human disease: on-line databases, supplement 3. Genes Immun. 7: 269-276 (2006). *

• Holmoy T, Hestvik AL.. Multiple sclerosis: immunopathogenesis and controversies in defining the cause. Curr. Opin. Infect. Dis. 21: 271-278 (2008).

• Holt SK, Kwon EM, Peters U, Ostrander EA, Stanford JL. Vitamin D pathway gene variants and prostate cancer risk. Cancer Epidemiol. Biomarkers Prev. 18: 1929-1933 (2009).

• Holubar SD, Long KH, Loftus EV Jr, Wolff BG, Pemberton JH, Cima RR. Long-term direct costs before and after proctocolectomy for ulcerative colitis: a population-based study in olmsted county, Minnesota. Dis. Colon Rectum 52: 1815-1823 (2009).

• Holzapfel C, Klopp N, Grallert H, Huth C, Gieger C, Meisinger C, Strassburger K, Giani G, Wichmann HE, Laumen H, Hauner H, Herder C, Rathmann W, Illig T. Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor (ARHGEF12) gene are not associated with T2DM and related parameters in Caucasians (KORA study). Eur. J. Endocrinol. 157: R1-R5 (2007). *

• Hong MG, Pawitan Y, Magnusson PK, Prince JA. Strategies and issues in the detection of pathway enrichment in genome-wide association studies. Hum. Genet. 126: 289-301 (2009). *

• Hong YS, Lee HJ, You CH, Roh MS, Kwak JY, Lee MJ, Kim JY. DNMT3b 39179GT polymorphism and the risk of adenocarcinoma of the colon in Koreans. Biochem. Genet. 45: 155-163 (2007). *

• Honiden S, Gong MN. Diabetes, insulin, and development of acute lung injury. Crit. Care Med. 37: 2455-2464 (2009).

• Honjo S, Kono S, Coleman MP, Shinchi K, Sakurai Y, Todoroki I, Umeda T, Wakabayashi K, Imanishi K, Nishikawa H, Ogawa S, Katsurada M, Nakagawa K, Yoshizawa N. Coffee consumption and serum aminotransferases in middle-aged Japanese men. J. Clin. Epidemiol. 54: 823-829 (2001).

• Hoogerwerf WA, Soloway RD. Gallstones. Curr. Opin. Gastroenterol. 15: 442 (1999).

• Hopman EG, von Blomberg ME, Batstra MR, Morreau H, Dekker FW, Koning F, Lamers CB, Mearin ML. Gluten tolerance in adult patients with celiac disease 20 years after diagnosis? Eur. J. Gastroenterol. Hepatol. 20: 423-429 (2008).

• Hopper JL. Application of genetics to the prevention of colorectal cancer. Recent Results Cancer Res. 166: 17-33 (2005).

• Horiuchi T, Washio M, Kiyohara C, Tsukamoto H, Tada Y, Asami T, Ide S, Kobashi G, Takahashi H; and the Kyushu Sapporo SLE Study Group. Combination of TNF-RII, CYP1A1 and GSTM1 polymorphisms and the risk of Japanese SLE: findings from the KYSS study. Rheumatology (Oxford) 48: 1045-1049 (2009).

• Horvitz G, Gold BD. Gastroduodenal diseases of childhood. Curr. Opin. Gastroenterol. 22: 632-640 (2006).

• Hou L, Xu J, Gao YT, Rashid A, Zheng SL, Sakoda LC, Shen MC, Wang BS, Deng J, Han TQ, Zhang BH, Meyers DA, Fraumeni JF Jr, Hsing AW. CYP17 MspA1 polymorphism and risk of biliary tract cancers and gallstones: a population-based study in Shanghai, China. Int. J. Cancer 118: 2847-2853 (2006). *

• Houlston RS, Ford D. Genetics of coeliac disease. QJM 89: 737-743 (1996).

• Hovingh GK, de Groot E, van der Steeg W, Boekholdt SM, Hutten BA, Kuivenhoven JA, Kastelein JJ. Inherited disorders of HDL metabolism and atherosclerosis. Curr. Opin. Lipidol. 16: 139-145 (2005).

• Howel D, Fischbacher CM, Bhopal RS, Gray J, Metcalf JV, James OF. An exploratory population-based case-control study of primary biliary cirrhosis. Hepatology 31: 1055-1060 (2000). *

• Howel D, Metcalf JV, Gray J, Newman WL, Jones DE, James OF. Cancer risk in primary biliary cirrhosis: a study in northern England. Gut 45: 756-760 (1999). *

• Howitz M, Krause TG, Simonsen JB, Hoffmann S, Frisch M, Nielsen NM, Robbins J, Schneerson R, Molbak K, Miller MA. Lack of association between group B meningococcal disease and autoimmune disease. Clin. Infect. Dis. 45: 1327-1334 (2007). *

• Howitz MF, Simonsen J, Krause TG, Robbins JB, Schneerson R, Molbak K, Miller MA. Risk of adverse birth outcome after group B meningococcal disease: results from a Danish national cohort. Pediatr. Infect. Dis. J. 28: 199-203 (2009).

• Hsing AW, Gao YT, McGlynn KA, Niwa S, Zhang M, Han TQ, Wang BS, Chen J, Sakoda LC, Shen MC, Zhang BH, Deng J, Rashid A. Biliary tract cancer and stones in relation to chronic liver conditions: a population-based study in Shanghai, China. Int. J. Cancer 120: 1981-1985 (2007). *

• Huang Q, Shete S, Swartz M, Amos CI. Examining the effect of linkage disequilibrium on multipoint linkage analysis. BMC Genet. 6 Suppl. 1: S83 (2005). *

• Huang WY, Gao YT, Rashid A, Sakoda LC, Deng J, Shen MC, Wang BS, Han TQ, Zhang BH, Chen BE, Rosenberg PS, Chanock S, Hsing AW. Selected base excision repair gene polymorphisms and susceptibility to biliary tract cancer and biliary stones: a population-based case-control study in China. Carcinogenesis 29: 100-105 (2008). *

• Huber A, Menconi F, Corathers S, Jacobson EM, Tomer Y. Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms. Endocr. Rev. 29: 697-725 (2008). *

• Huber R, Ditfurth AV, Amann F, Guthlin C, Rostock M, Trittler R, Kummerer K, Merfort I. Tormentil for active ulcerative colitis: an open-label, dose-escalating study. J. Clin. Gastroenterol. 41: 834-838 (2007).

• Huebner C, Petermann I, Browning BL, Shelling AN, Ferguson LR. Triallelic single nucleotide polymorphisms and genotyping error in genetic epidemiology studies: MDR1 (ABCB1) G2677/T/A as an example. Cancer Epidemiol. Biomarkers Prev. 16: 1185-1192 (2007). *

• Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olson JM, Lee JC, Beaugerie L, Naom I, Dupas JL, Van Gossum A, Orholm M, Bonaiti-Pellie C, Weissenbach J, Mathew CG, Lennard-Jones JE, Cortot A, Colombel JF, Thomas G. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 379: 821-823 (1996). *

• Hugot JP, Zouali H, Lesage S, Thomas G. Etiology of the inflammatory bowel diseases. Int. J. Colorectal Dis. 14: 2-9 (1999). *

• Huh SY, Gordon CM. Vitamin D deficiency in children and adolescents: epidemiology, impact and treatment. Rev. Endocr. Metab. Disord. 9: 161-170 (2008). *

• Humphrey LL, Fu R, Rogers K, Freeman M, Helfand M. Homocysteine level and coronary heart disease incidence: a systematic review and meta-analysis. Mayo Clin. Proc. 83: 1203-1212 (2008).

• Hunder GG. Epidemiology of giant-cell arteritis. Cleve. Clin. J. Med. 69 Suppl. 2: SII79-SII82 (2002).

• Hung HC, Joshipura KJ, Jiang R, Hu FB, Hunter D, Smith-Warner SA, Colditz GA, Rosner B, Spiegelman D, Willett WC. Fruit and vegetable intake and risk of major chronic disease. J. Natl. Cancer Inst. 96: 1577-1584 (2004). *

• Hunter DJ. Gene-environment interactions in human diseases. Nat. Rev. Genet. 6: 287-298 (2005). *

• Hunter DJ. The influence of genetic polymorphism. J. Nutr. 136: 2711S-2713S (2006). *

• Hunter DJ, Khoury MJ, Drazen JM. Letting the genome out of the bottle - will we get our wish? N. Engl. J. Med. 358: 105-107 (2008). *

• Hunter DJ, Kraft P. Drinking from the fire hose - statistical issues in genomewide association studies. N. Engl. J. Med. 357: 436-439 (2007). *

• Hutfless SM, Weng X, Liu L, Allison J, Herrinton LJ. Mortality by medication use among patients with inflammatory bowel disease, 1996-2003. Gastroenterology 133: 1779-1786 (2007). *

• Huth C, Illig T, Herder C, Gieger C, Grallert H, Vollmert C, Rathmann W, Hamid YH, Pedersen O, Hansen T, Thorand B, Meisinger C, Doring A, Klopp N, Gohlke H, Lieb W, Hengstenberg C, Lyssenko V, Groop L, Ireland H, Stephens JW, et al. Joint analysis of individual participants' data from 17 studies on the association of the IL6 variant -174G >C with circulating glucose levels, interleukin-6 levels, and body mass index. Ann. Med. 41: 128-138 (2009).

• Hviid A, Stellfeld M, Wohlfahrt J, Melbye M. Childhood vaccination and type 1 diabetes. N. Engl. J. Med. 350: 1398-1404 (2004). *

• Hyrich KL. Assessing the safety of biologic therapies in rheumatoid arthritis: the challenges of study design. J. Rheumatol. Suppl. 72: 48-50 (2005). *

• Hyrich KL, Deighton C, Watson KD; BSRBR Control Centre Consortium, Symmons DP, Lunt M; on behalf of the British Society for Rheumatology Biologics Register. Benefit of anti-TNF therapy in rheumatoid arthritis patients with moderate disease activity. Rheumatology (Oxford) 48: 1323-1327 (2009).

• Hyrich KL, Lunt M, Dixon WG, Watson KD, Symmons DP; on behalf of the BSR Biologics Register. Effects of switching between anti-TNF therapies on HAQ response in patients who do not respond to their first anti-TNF drug. Rheumatology (Oxford) 47: 1000-1005 (2008). *

• Hyrich KL, Watson KD, Silman AJ, Symmons DP. Predictors of response to anti-TNF-alpha therapy among patients with rheumatoid arthritis: results from the British Society for Rheumatology Biologics Register. Rheumatology (Oxford) 45: 1558-1565 (2006). *

• Ibrahim GH, Buch MH, Lawson C, Waxman R, Helliwell PS. Evaluation of an existing screening tool for psoriatic arthritis in people with psoriasis and the development of a new instrument: the Psoriasis Epidemiology Screening Tool (PEST) questionnaire. Clin. Exp. Rheumatol. 27: 469-474 (2009).

• Idestrom M, Rubio C, Granath F, Finkel Y, Hugot JP. CARD15 mutations are rare in Swedish pediatric Crohn disease. J. Pediatr. Gastroenterol. Nutr. 40: 456-460 (2005). *

• Igo RP Jr, Londono D, Miller K, Parrado AR, Quade SR, Sinha M, Kim S, Won S, Li J, Goddard KA. Density-based clustering in haplotype analysis for association mapping. BMC Proc. 1 Suppl. 1: S27 (2007). *

• Ikeda S, Sasazuki S, Natsukawa S, Shaura K, Koizumi Y, Kasuga Y, Ohnami S, Sakamoto H, Yoshida T, Iwasaki M, Tsugane S. Screening of 214 single nucleotide polymorphisms in 44 candidate cancer susceptibility genes: a case-control study on gastric and colorectal cancers in the Japanese population. Am. J. Gastroenterol. 103: 1476-1487 (2008). *

• Ikehara SK, Ikehara Y, Matsuo K, Hirose K, Niwa T, Ito H, Ito S, Kodera Y, Yamamura Y, Nakanishi H, Tatematsu M, Tajima K. A polymorphism of C-to-T substitution at -31 IL1B is associated with the risk of advanced gastric adenocarcinoma in a Japanese population. J. Hum. Genet. 51: 927-933 (2006). *

• Ikram MA, Seshadri S, Bis JC, Fornage M, Destefano AL, Aulchenko YS, Debette S, Lumley T, Folsom AR, van den Herik EG, Bos MJ, Beiser A, Cushman M, Launer LJ, Shahar E, Struchalin M, Du Y, Glazer NL, Rosamond WD, Rivadeneira F, Kelly-Hayes M, et al. Genomewide association studies of stroke. N. Engl. J. Med. 360: 1718-1728 (2009). *

• Illig T, Bongardt F, Schopfer A, Holle R, Muller S, Rathmann W, Koenig W, Meisinger C, Wichmann HE, Kolb H; KORA Study Group. The endotoxin receptor TLR4 polymorphism is not associated with diabetes or components of the metabolic syndrome. Diabetes 52: 2861-2864 (2003). *

• Illig T, Gieger C, Zhai G, Romisch-Margl W, Wang-Sattler R, Prehn C, Altmaier E, Kastenmuller G, Kato BS, Mewes HW, Meitinger T, de Angelis MH, Kronenberg F, Soranzo N, Wichmann HE, Spector TD, Adamski J, Suhre K. A genome-wide perspective of genetic variation in human metabolism. Nat. Genet. Dec 27 [Epub ahead of print] (2009). *

• Imbert Y, Foulks GN, Brennan MD, Jumblatt MM, John G, Shah HA, Newton C, Pouranfar F, Young WW Jr. MUC1 and estrogen receptor alpha gene polymorphisms in dry eye patients. Exp. Eye Res. 88: 334-338 (2009). *

• Imboden M, Nicod L, Nieters A, Glaus E, Matyas G, Bircher AJ, Ackermann-Liebrich U, Berger W, Probst-Hensch NM; SAPALDIA Team. The common G-allele of interleukin-18 single-nucleotide polymorphism is a genetic risk factor for atopic asthma. The SAPALDIA Cohort Study. Clin. Exp. Allergy 36: 211-218 (2006).

• Immervoll T, Loesgen S, Dutsch G, Gohlke H, Herbon N, Klugbauer S, Dempfle A, Bickeboller H, Becker-Follmann J, Ruschendorf F, Saar K, Reis A, Wichmann HE, Wjst M. Fine mapping and single nucleotide polymorphism association results of candidate genes for asthma and related phenotypes. Hum. Mutat. 18: 327-336 (2001). *

• in t' Veld BA, Ruitenberg A, Hofman A, Launer LJ, van Duijn CM, Stijnen T, Breteler MM, Stricker BH. Nonsteroidal antiinflammatory drugs and the risk of Alzheimer's disease. N. Engl. J. Med. 345: 1515-1521 (2001). *

• Ingordo V, Gentile C, Iannazzone S, Cusano F, Naldi L. The 'EpiEnlist' project: a dermo-epidemiologic study on a representative sample of young Italian males. Prevalence of selected pigmentary lesions. J. Eur. Acad. Dermatol. Venereol. 21: 1091-1096 (2007). *

• Inoue M, Yoshimi I, Sobue T, Tsugane S; JPHC Study Group. Influence of coffee drinking on subsequent risk of hepatocellular carcinoma: a prospective study in Japan. J. Natl. Cancer Inst. 97: 293-300 (2005). *

• International MHC and Autoimmunity Genetics Network (IMAGEN), Rioux JD, Goyette P, Vyse TJ, Hammarstrom L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, Annese V, Hafler DA, et al. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc. Natl. Acad. Sci. U.S.A. 106: 18680-18685 (2009). *

• Invernizzi P. Geoepidemiology of autoimmune liver diseases. J. Autoimmun. Dec 23 [Epub ahead of print] (2009).

• Ioannidis JP, Allison DB, Ball CA, Coulibaly I, Cui X, Culhane AC, Falchi M, Furlanello C, Game L, Jurman G, Mangion J, Mehta T, Nitzberg M, Page GP, Petretto E, van Noort V. Repeatability of published microarray gene expression analyses. Nat. Genet. 41: 149-155 (2009). *

• Ioannidis JP, Ntzani EE, Trikalinos TA. 'Racial' differences in genetic effects for complex diseases. Nat. Genet. 36: 1312-1318 (2004). *

• Ioannou GN, Weiss NS, Boyko EJ, Kakn SE, Lee SP. Contribution of metabolic factors to alanine aminotransferase activity in persons with other causes of liver disease. Gastroenterology 128: 627-635 (2005). *

• Ishii E, Ohga S, Imashuku S, Yasukawa M, Tsuda H, Miura I, Yamamoto K, Horiuchi H, Takada K, Ohshima K, Nakamura S, Kinukawa N, Oshimi K, Kawa K. Nationwide survey of hemophagocytic lymphohistiocytosis in Japan. Int. J. Hematol. 86: 58-65 (2007).

• Ivarsson A. The Swedish epidemic of coeliac disease explored using an epidemiological approach-some lessons to be learnt. Best Pract. Res. Clin. Gastroenterol. 19: 425-440 (2005).

• Iyengar SK, Elston RC. The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol. Biol. 376: 71-84 (2007).

• Jabs DA, Gerard HC, Wei Y, Campbell AL, Hudson AP, Akpek EK, Lee B, Prendergast RA, Whittum-Hudson JA. Inflammatory mediators in autoimmune lacrimal gland disease in MRL/Mpj mice. Invest. Ophthalmol. Vis. Sci. 45: 2293-2298 (2004). *

• Jackson H, Solaymani-Dodaran M, Card TR, Aithal GP, Logan R, West J. Influence of ursodeoxycholic acid on the mortality and malignancy associated with primary biliary cirrhosis: a population-based cohort study. Hepatology 46: 1131-1137 (2007). *

• Jackson L, Britton J, Lewis SA, McKeever TM, Atherton J, Fullerton D, Fogarty AW. A population-based epidemiologic study of Helicobacter pylori infection and its association with systemic inflammation. Helicobacter 14: 108-113 (2009). *

• Jacobs KB, Yeager M, Wacholder S, Craig D, Kraft P, Hunter DJ, Paschal J, Manolio TA, Tucker M, Hoover RN, Thomas GD, Chanock SJ, Chatterjee N. A new statistic and its power to infer membership in a genome-wide association study using genotype frequencies. Nat. Genet. 41: 1253-1257 (2009). *

• Jacobsen BA, Fallingborg J, Rasmussen HH, Nielsen KR, Drewes AM, Puho E, Nielsen GL, Sorensen HT. Increase in incidence and prevalence of inflammatory bowel disease in northern Denmark: a population-based study, 1978-2002. Eur. J. Gastroenterol. Hepatol. 18: 601-606 (2006).

• Jacobson DL, Gange SJ, Rose NR, Graham NM. Epidemiology and estimated population burden of selected autoimmune diseases in the United States. Clin. Immunol. Immunopathol. 84: 223-243 (1997).

• Jacobson EM, Huber A, Tomer Y. The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. J. Autoimmun. 30: 58-62 (2008). *

• Jacobson TA, Miller M, Schaefer EJ. Hypertriglyceridemia and cardiovascular risk reduction. Clin. Ther. 29: 763-777 (2007).

• Jacobsson G, Dashti S, Wahlberg T, Andersson R. The epidemiology of and risk factors for invasive Staphylococcus aureus infections in western Sweden. Scand. J. Infect. Dis. 39: 6-13 (2007). *

• Jakob E, Reuland MS, Mackensen F, Harsch N, Fleckenstein M, Lorenz HM, Max R, Becker MD. Uveitis subtypes in a German Interdisciplinary Uveitis Center - analysis of 1916 patients. J. Rheumatol. 36: 127-136 (2009).

• Jallow M, Teo YY, Small KS, Rockett KA, Deloukas P, Clark TG, Kivinen K, Bojang KA, Conway DJ, Pinder M, Sirugo G, Sisay-Joof F, Usen S, Auburn S, Bumpstead SJ, Campino S, Coffey A, Dunham A, Fry AE, Green A, Gwilliam R, Hunt SE, Inouye M, et al. Genome-wide and fine-resolution association analysis of malaria in West Africa. Nat. Genet. 41: 657-665 (2009). *

• James OFW. Epidemiology of primary biliary cirrhosis. Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper’s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 17. October 15-16 (2003). *

• Jamra RA, Becker T, Klopp N, Dahdouh F, Schulze TG, Gross M, Deschner M, Schmal C, Illig T, Rietschel M, Propping P, Cichon S, Nothen MM, Schumacher J. No evidence for an association between variants at the gamma-amino-n-butyric acid type A receptor beta2 locus and schizophrenia. Psychiatr. Genet. 17: 43-45 (2007).

• Jamshidi F, Bouzari N, Seirafi H, Farnaghi F, Firooz A. The prevalence of psoriatic arthritis in psoriatic patients in Tehran, Iran. Arch. Iran. Med. 11: 162-165 (2008).

• Jankovic S, Raznatovic M, Marinkovic J, Jankovic J, Maksimovic N. Risk factors for psoriasis: a case-control study. J. Dermatol. 36: 328-334 (2009).

• Jankovic S, Raznatovic M, Marinkovic J, Maksimovic N, Jankovic J, Djikanovic B. Relevance of psychosomatic factors in psoriasis: a case-control study. Acta Derm. Venereol. 89: 364-368 (2009).

• Jansen AC, van Aalst-Cohen ES, Tanck MW, Cheng S, Fontecha MR, Li J, Defesche JC, Kastelein JJ. Genetic determinants of cardiovascular disease risk in familial hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol. 25: 1475-1481 (2005). *

• Jehn M, Clark JM, Guallar E. Serum ferritin and risk of the metabolic syndrome in U.S. adults. Diabetes Care 27: 2422-2428 (2004). *

• Jelsbak L, Johansen HK, Frost AL, Thogersen R, Thomsen LE, Ciofu O, Yang L, Haagensen JA, Hoiby N, Molin S. Molecular epidemiology and dynamics of Pseudomonas aeruginosa populations in cystic fibrosis lungs. Infect. Immun. 75: 2214-2224 (2007). *

• Jenab M, McKay J, Bueno-de-Mesquita HB, van Duijnhoven FJ, Ferrari P, Slimani N, Jansen EH, Pischon T, Rinaldi S, Tjonneland A, Olsen A, Overvad K, Boutron-Ruault MC, Clavel-Chapelon F, Engel P, Kaaks R, Linseisen J, Boeing H, Fisher E, et al. Vitamin D receptor and calcium sensing receptor polymorphisms and the risk of colorectal cancer in European populations. Cancer Epidemiol. Biomarkers Prev. 18: 2485-2491 (2009). *

• Jensen AB, Larsen M, Gislum M, Skriver MV, Jepsen P, Norgaard B, Sorensen HT. Survival after colorectal cancer in patients with ulcerative colitis: a nationwide population-based Danish study. Am. J. Gastroenterol. 101: 1283-1287 (2006). *

• Jensen K, Gluud C. The Mallory body: morphological, clinical and experimental studies (Part 1 of a literature survey). Hepatology 20: 1061-1077 (1994).

• Jeong SH, Lee HS. Hepatitis A: clinical manifestations and management. Intervirology 53: 15-19 (2010).

• Jepsen P, Vilstrup H, Andersen PK, Lash TL, Sorensen HT. Comorbidity and survival of Danish cirrhosis patients: a nationwide population-based cohort study. Hepatology 48: 214-220 (2008). *

• Jepsen P, Vilstrup H, Tarone RE, Friis S, Sorensen HT. Incidence rates of intra- and extrahepatic cholangiocarcinomas in Denmark from 1978 through 2002. J. Natl. Cancer Inst. 99: 895-897 (2007). *

• Jess T, Gamborg M, Matzen P, Munkholm P, Sorensen TI. Increased risk of intestinal cancer in Crohn's disease: a meta-analysis of population-based cohort studies. Am. J. Gastroenterol. 100: 2724-2729 (2005). *

• Jess T, Loftus EV Jr, Velayos FS, Harmsen WS, Zinsmeister AR, Smyrk TC, Schleck CD, Tremaine WJ, Melton LJ 3rd, Munkholm P, Sandborn WJ. Risk of intestinal cancer in inflammatory bowel disease: a population-based study from Olmsted County, Minnesota. Gastroenterology 130: 1039-1046 (2006). *

• Jess T, Loftus EV Jr, Velayos FS, Harmsen WS, Zinsmeister AR, Smyrk TC, Tremaine WJ, Melton LJ 3rd, Munkholm P, Sandborn WJ. Incidence and prognosis of colorectal dysplasia in inflammatory bowel disease: a population-based study from Olmsted County, Minnesota. Inflamm. Bowel Dis. 12: 669-676 (2006). *

• Jess T, Riis L, Jespersgaard C, Hougs L, Andersen PS, Orholm MK, Binder V, Munkholm P. Disease concordance, zygosity, and NOD2/CARD15 status: follow-up of a population-based cohort of Danish twins with inflammatory bowel disease. Am. J. Gastroenterol. 100: 2486-2492 (2005). *

• Jiang J, Zhang X, Yang H, Wang W. Polymorphisms of DNA repair genes: ADPRT, XRCC1, and XPD and cancer risk in genetic epidemiology. Methods Mol. Biol. 471: 305-333 (2009). *

• Jiang L, Xia B, Li J, Ye M, Deng C, Ding Y, Luo H, Ren H, Hou X, Liu H, Xu H, Cheng H, Yang H. Risk factors for ulcerative colitis in a Chinese population: an age-matched and sex-matched case-control study. J. Clin. Gastroenterol. 41: 280-284 (2007).

• Jiang Q, Chen K, Ma X, Li Q, Yu W, Shu G, Yao K. Diets, polymorphisms of methylenetetrahydrofolate reductase, and the susceptibility of colon cancer and rectal cancer. Cancer Detect. Prev. 29: 146-154 (2005).

• Jiang XL, Cui HF. An analysis of 10218 ulcerative colitis cases in China. World J. Gastroenterol. 8: 158-161 (2002). *

• Jiang Y, Obuseh F, Ellis W, Piyathilake C, Jolly P. Association of vitamin A deficiency with decrease in TNF-alpha expressing CD3-CD56+ NK cells in Ghanaians. Nutr. Res. 27: 400-407 (2007). *

• Jin MJ, Chen K, Song L, Fan CH, Chen Q, Zhu YM, Ma XY, Yao KY. The association of the DNA repair gene XRCC3 Thr241Met polymorphism with susceptibility to colorectal cancer in a Chinese population. Cancer Genet. Cytogenet. 163: 38-43 (2005).

• Jin MJ, Chen K, Zhang Y, Zhang W, Liu B, Zhang YJ. Correlations of single nucleotide polymorphisms of DNA repair gene XRCC1 to risk of colorectal cancer. Ai Zheng 26: 274-279 (2007).

• Johannesen J, Pociot F, Kristiansen OP, Karlsen AE, Nerup J; DIEGG and DSGD Danish IDDM Epidemiology and Genetics Group, Danish Study Group of Diabetis in Childhood. No evidence for linkage in the promoter region of the inducible nitric oxide synthase gene (NOS2) in a Danish type 1 diabetes population. Genes Immun. 1: 362-366 (2000). *

• Johannesson M, Askling J, Montgomery SM, Ekbom A, Bahmanyar S. Cancer risk among patients with cystic fibrosis and their first degree relatives. Int. J. Cancer 125: 2953-2956 (2009). *

• John S, Eyre S, Myerscough A, Barrett J, Silman A, Ollier W, Worthington J. Linkage and association analysis of candidate genes in rheumatoid arthritis. J. Rheumatol. 28: 1752-1755 (2001).

• John S, Marlow A, Hajeer A, Ollier W, Silman A, Worthington J. Linkage and association studies of the natural resistance associated macrophage protein 1 (NRAMP1) locus in rheumatoid arthritis. J. Rheumatol. 24: 452-457 (1997).

• John S, Worthington J. Genetic epidemiology. Approaches to the genetic analysis of rheumatoid arthritis. Arthritis Res. 3: 216-220 (2001). *

• Johswich K, Martin M, Bleich A, Kracht M, Dittrich-Breiholz O, Gessner JE, Suerbaum S, Wende E, Rheinheimer C, Klos A. Role of the C5a receptor (C5aR) in acute and chronic dextran sulfate-induced models of inflammatory bowel disease. Inflamm. Bowel Dis. 15: 1812-1823 (2009). *

• Jones DE, Bhala N, Burt J, Goldblatt J, Prince M, Newton JL. Four year follow up of fatigue in a geographically defined primary biliary cirrhosis patient cohort. Gut 55: 536-541 (2006). *

• Jones JS, Gu X, Lynch PM, Rodriguez-Bigas M, Amos CI, Frazier ML. ATM polymorphism and hereditary nonpolyposis colorectal cancer (HNPCC) age of onset (United States). Cancer Causes Control 16: 749-753 (2005). *

• Jones NE, Dhaliwal R, Day AG, Jiang X, Heyland DK. Nutrition therapy in the critical care setting: what is "best achievable" practice? An international multicenter observational study. Crit. Care Med. Oct 20 [Epub ahead of print] (2009).

• Jones NE, Heyland DK. Pharmaconutrition: a new emerging paradigm. Curr. Opin. Gastroenterol. 24: 215-222 (2008).

• Jonsson BE, Gilljam M, Lindblad A, Ridell M, Wold AE, Welinder-Olsson C. Molecular epidemiology of Mycobacterium abscessus, with focus on cystic fibrosis. J. Clin. Microbiol. 45: 1497-1504 (2007). *

• Joossens S, Vermeire S, Van Steen K, Godefridis G, Claessens G, Pierik M, Vlietinck R, Aerts R, Rutgeerts P, Bossuyt X. Pancreatic autoantibodies in inflammatory bowel disease. Inflamm. Bowel Dis. 10: 771-777 (2004). *

• Jorgen Secher N. Does fish oil prevent preterm birth? J. Perinat. Med. 35 Suppl. 1: S25-S27 (2007).

• Jorgensen ME, Bjerregaard P, Kjaergaard JJ, Borch-Johnsen K. High prevalence of markers of coronary heart disease among Greenland Inuit. Atherosclerosis 196: 772-778 (2008).

• Jorgenson E, Witte JS. Genome-wide association studies of cancer. Future Oncol. 3: 419-427 (2007).

• Juang CM, Hung CF, Yeh JY, Horng HC, Twu NF, Cheng MH, Wen KC, Yuan CC, Chao KC, Wu TC, Yen MS. Regulatory T cells: potential target in anticancer immunotherapy. Taiwan J. Obstet. Gynecol. 46: 215-221 (2007).

• Juillerat P, Pittet V, Bulliard JL, Guessous I, Antonino AT, Mottet C, Felley C, Vader JP, Michetti P. Prevalence of inflammatory bowel disease in the Canton of Vaud (Switzerland): a population-based cohort study. Journal of Crohn's and Colitis 2: 131-141 (2008).

• Jung HK, Choung RS, Locke GR 3rd, Schleck CD, Zinsmeister AR, Szarka LA, Mullan B, Talley NJ. The incidence, prevalence, and outcomes of patients with gastroparesis in Olmsted County, Minnesota, from 1996 to 2006. Gastroenterology 136: 1225-1233 (2009).

• Jung JS, Park BL, Cheong HS, Bae JS, Kim JH, Chang HS, Rhym T, Park JS, Jang AS, Lee YM, Kim KU, Uh ST, Na JO, Kim YH, Park CS, Shin HD. Association of IL17RB gene polymorphism with asthma. Chest 135: 1173-1180 (2009). *

• Jurj AL, Wen W, Li HL, Zheng W, Yang G, Xiang YB, Gao YT, Shu XO. Spousal correlations for lifestyle factors and selected diseases in Chinese couples. Ann. Epidemiol. 16: 285-291 (2006).

• Kaae J, Wohlfahrt J, Boyd HA, Wulf HC, Biggar RJ, Melbye M. The impact of autoimmune diseases on the incidence and prognosis of cutaneous malignant melanoma. Cancer Epidemiol. Biomarkers Prev. 16: 1840-1844 (2007). *

• Kaguelidou F, Alberti C, Castanet M, Guitteny MA, Czernichow P, Leger J; the French Childhood Graves' Disease Study Group. Predictors of autoimmune hyperthyroidism relapse in children after discontinuation of antithyroid drug treatment. J. Clin. Endocrinol. Metab. 93: 3817-3826 (2008). *

• Kakourou T, Karachristou K, Chrousos G. A case series of alopecia areata in children: impact of personal and family history of stress and autoimmunity. J. Eur. Acad. Dermatol. Venereol. 21: 356-359 (2007). *

• Kalantar-Zadeh K, Balakrishnan VS. The kidney disease wasting: inflammation, oxidative stress, and diet-gene interaction. Hemodial. Int. 10: 315-325 (2006). *

• Kampman MT, Brustad M. Vitamin D: a candidate for the environmental effect in multiple sclerosis - observations from Norway. Neuroepidemiology 30: 140-146 (2008). *

• Kant AK, Graubard BI. Ethnic and socioeconomic differences in variability in nutritional biomarkers. Am. J. Clin. Nutr. 87: 1464-1471 (2008). *

• Kantarci O, Wingerchuk D. Epidemiology and natural history of multiple sclerosis: new insights. Curr. Opin. Neurol. 19: 248-254 (2006).

• Kapetanovic R, Cavaillon JM. Early events in innate immunity in the recognition of microbial pathogens. Expert Opin. Biol. Ther. 7: 907-918 (2007).

• Kaplan GG, Laupland KB, Butzner D, Urbanski SJ, Lee SS. The burden of large and small duct primary sclerosing cholangitis in adults and children: a population-based analysis. Am. J. Gastroenterol. 102: 1042-1049 (2007). *

• Kappelman MD, Bousvaros A. Nutritional concerns in pediatric inflammatory bowel disease patients. Mol. Nutr. Food Res. 52: 867-874 (2008). *

• Karami S, Brennan P, Hung RJ, Boffetta P, Toro J, Wilson RT, Zaridze D, Navratilova M, Chatterjee N, Mates D, Janout V, Kollarova H, Bencko V, Szeszenia-Dabrowska N, Holcatova I, Moukeria A, Welch R, Chanock S, Rothman N, Chow WH, Moore LE. Vitamin D receptor polymorphisms and renal cancer risk in Central and Eastern Europe. J. Toxicol. Environ. Health A. 71: 367-372 (2008).

• Karami S, Brennan P, Navratilova M, Mates D, Zaridze D, Janout V, Kollarova H, Bencko V, Matveev V, Szesznia-Dabrowska N, Holcatova I, Yeager M, Chanock S, Rothman N, Boffetta P, Chow WH, Moore LE. Vitamin D pathway genes, diet, and risk of renal cell carcinoma. Int. J. Endocrinol. 2010: 879362 (2010). *

• Karami S, Brennan P, Rosenberg PS, Navratilova M, Mates D, Zaridze D, Janout V, Kollarova H, Bencko V, Matveev V, Szeszenia-Dabrowska N, Holcatova I, Yeager M, Chanock S, Menashe I, Rothman N, Chow WH, Boffetta P, Moore LE. Analysis of SNPs and haplotypes in vitamin D pathway genes and renal cancer risk. PLoS One 4: e7013 (2009). *

• Karanicolas PJ, Dubois L, Colquhoun PH, Swallow CJ, Walter SD, Guyatt GH. The more the better?: the impact of surgeon and hospital volume on in-hospital mortality following colorectal resection. Ann. Surg. 249: 954-959 (2009).

• Karanja RM, Gatei W, Wamae N. Cyclosporiasis: an emerging public health concern around the world and in Africa. Afr. Health Sci. 7: 62-67 (2007).

• Karasneh J, Gul A, Ollier WE, Silman AJ, Worthington J. Whole-genome screening for susceptibility genes in multicase families with Behcet's disease. Arthritis Rheum. 52: 1836-1842 (2005). *

• Karasneh JA, Hajeer AH, Silman A, Worthington J, Ollier WE, Gul A. Polymorphisms in the endothelial nitric oxide synthase gene are associated with Behcet's disease. Rheumatology (Oxford) 44: 614-617 (2005). *

• Karassa FB, Trikalinos TA, Ioannidis JP. The role of FcgammaRIIA and IIIA polymorphisms in autoimmune diseases. Biomed. Pharmacother. 58: 286-291 (2004).

• Karassa FB, Trikalinos TA, Ioannidis JP; FcgammaRIIa-SLE Meta-Analysis Investigators. Role of the Fcgamma receptor IIa polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. Arthritis Rheum. 46: 1563-1571 (2002). *

• Karban A, Waterman M, Panhuysen CI, Pollak RD, Nesher S, Datta L, Weiss B, Suissa A, Shamir R, Brant SR, Eliakim R. NOD2/CARD15 genotype and phenotype differences between Ashkenazi and Sephardic jews with Crohn's disease. Am. J. Gastroenterol. 99: 1134-1140 (2004). *

• Karlinger K, Gyorke T, Mako E, Mester A, Tarjan Z. The epidemiology and the pathogenesis of inflammatory bowel disease. Eur. J. Radiol. 35: 154-167 (2000).

• Karlsen TH, Schrumpf E, Boberg KM. Genetic epidemiology of primary sclerosing cholangitis. World J. Gastroenterol. 13: 5421-5431 (2007). *

• Karolewska-Bochenek K, Lazowska-Przeorek I, Albrecht P, Grzybowska K, Ryzko J, Szamotulska K, Radzikowski A, Landowski P, Krzesiek E, Ignys I, Fyderek K, Czerwionka-Szaflarska M, Jarocka-Cyrta E. Epidemiology of inflammatory bowel disease among children in Poland. A prospective, population-based, 2-year study, 2002-2004. Digestion 79: 121-129 (2009).

• Kasper S, Huhulescu S, Auer B, Heller I, Karner F, Wurzner R, Wagner M, Allerberger F. Epidemiology of listeriosis in Austria. Wien. Klin. Wochenschr. 121: 113-119 (2009).

• Katz J, Reynolds JC. Clinical management of premalignant disorders of the gastrointestinal tract. Gastroenterol. Clin. N. Am. 31: xv-xvi (2002). *

• Katz JA, Antoni C, Keenan GF, Smith DE, Jacobs SJ, Lichtenstein GR. Outcome of pregnancy in women receiving infliximab for the treatment of Crohn's disease and rheumatoid arthritis. Am. J. Gastroenterol. 99: 2385-2392 (2004). *

• Katz KA, Dick SE, Osterman MT, Junkins-Hopkins JM. Perianal skin tags in a patient with Crohn disease and a subclinical rectal stricture. Cutis 80: 429-431 (2007).

• Kaushik P. Palindromic rheumatism: a descriptive report of seven cases from North Dakota and a short review of literature. Clin. Rheumatol. Sep 22 [Epub ahead of print] (2009). *

• Kavvoura FK, Akamizu T, Awata T, Ban Y, Chistiakov DA, Frydecka I, Ghaderi A, Gough SC, Hiromatsu Y, Ploski R, Wang PW, Ban Y, Bednarczuk T, Chistiakova EI, Chojm M, Heward JM, Hiratani H, Juo SH, Karabon L, Katayama S, Kurihara S, Liu RT, Miyake I, et al. Cytotoxic T-lymphocyte associated antigen 4 gene polymorphisms and autoimmune thyroid disease: a meta-analysis. J. Clin. Endocrinol. Metab. 92: 3162-3170 (2007). *

• Kavvoura FK, Ioannidis JP. CTLA-4 gene polymorphisms and susceptibility to type 1 diabetes mellitus: a HuGE review and meta-analysis. Am. J. Epidemiol. 162: 3-16 (2005). *

• Kawase T, Matsuo K, Kashiwase K, Inoko H, Saji H, Ogawa S, Kato S, Sasazuki T, Kodera Y, Morishima Y. HLA mismatch combinations associated with decreased risk of relapse: implications for molecular mechanism. Blood 113: 2851-2858 (2009). *

• Ke X, Taylor MS, Cardon LR. Singleton SNPs in the human genome and implications for genome-wide association studies. Eur. J. Hum. Genet. 16: 506-515 (2008).

• Kelleher AD, Zaunders JJ. Decimated or missing in action: CD4+ T cells as targets and effectors in the pathogenesis of primary HIV infection. Curr. HIV/AIDS Rep. 3: 5-12 (2006).

• Kempen JH, Gangaputra S, Daniel E, Levy-Clarke GA, Nussenblatt RB, Rosenbaum JT, Suhler EB, Thorne JE, Foster CS, Jabs DA, Helzlsouer KJ. Long-term risk of malignancy among patients treated with immunosuppressive agents for ocular inflammation: a critical assessment of the evidence. Am. J. Ophthalmol. 146: 802-812.e1 (2008). *

• Kennedy AP, Nelson E, Reeves D, Richardson G, Roberts C, Robinson A, Rogers AE, Sculpher M, Thompson DG, the North-West Regional Gastrointestinal Research Group. A randomised controlled trial to assess the effectiveness and cost of a patient orientated self management approach to chronic inflammatory bowel disease. Gut 53: 1639-1645 (2004). *

• Kennedy J, O'Connor P, Sadovnick AD, Perara M, Yee I, Banwell B. Age at onset of multiple sclerosis may be influenced by place of residence during childhood rather than ancestry. Neuroepidemiology 26: 162-167 (2006).

• Kesselheim AS. Drug development for neglected diseases - the trouble with FDA review vouchers. N. Engl. J. Med. 359: 1981-1983 (2008). *

• Kevenaar ME, Laven JS, Fong SL, Uitterlinden AG, de Jong FH, Themmen AP, Visser JA. A functional anti-Mullerian hormone gene polymorphism is associated with follicle number and androgen levels in polycystic ovary syndrome patients. J. Clin. Endocrinol. Metab. 93: 1310-1316 (2008). *

• Key TJ, Appleby PN, Rosell MS. Health effects of vegetarian and vegan diets. Proc. Nutr. Soc. 65: 35-41 (2006). *

• Khan F, McPhail T, Brand C, Turner-Stokes L, Kilpatrick T. Multiple sclerosis: disability profile and quality of life in an Australian community cohort. Int. J. Rehabil. Res. 29: 87-96 (2006).

• Khan MA, Bass DM. Viral infections: new and emerging. Curr. Opin. Gastroenterol. 26: 26-30 (2010).

• Khan S, Orenstein SR. Eosinophilic gastroenteritis: epidemiology, diagnosis and management. Paediatr. Drugs 4: 563-570 (2002).

• Khan SA, Toledano MB, Taylor-Robinson SD. Epidemiology, risk factors, and pathogenesis of cholangiocarcinoma. HPB (Oxford) 10: 77-82 (2008). *

• Kharicha K, Iliffe S, Harari D, Swift C, Gillmann G, Stuck AE. Health risk appraisal in older people 1: are older people living alone an 'at-risk' group? Br. J. Gen. Pract. 57: 271-276 (2007).

• Khoury-Shakour S, Gruber SB, Lejbkowicz F, Rennert HS, Raskin L, Pinchev M, Rennert G. Recreational physical activity modifies the association between a common GH1 polymorphism and colorectal cancer risk. Cancer Epidemiol. Biomarkers Prev. 17: 3314-3318 (2008). *

• Khoury-Shakour S, Lejbkowicz F, Barnett-Griness O, Tamir A, Pinchev M, Rennert G. Genetic variation in IGF-1 and breast cancer risk in Ashkenazi carriers and noncarriers of BRCA1/2 mutations. Eur. J. Cancer Prev. 18: 361-367 (2009).

• Kianmanesh R, Scaringi S, Castel B, Flamant Y, Msika S. Precancerous lesions of the gallbladder. J. Chir. (Paris) 144: 278-286 (2007).

• Kiechle FL, Holland-Staley CA. Genomics, transcriptomics, proteomics, and numbers. Arch. Pathol. Lab. Med. 127: 1089-1097 (2003). *

• Kikuchi H, Murakami S, Suzuki S, Kudo H, Sassa S, Sakamoto S. Chemopreventive effect of a vitamin D3 analog, alfacalcidol, on colorectal carcinogenesis in mice with ulcerative colitis. Anticancer Drugs 18: 1183-1187 (2007).

• Kim H, Hutter CM, Monks SA, Edwards KL. Comparison of single-nucleotide polymorphisms and microsatellites in detecting quantitative trait loci for alcoholism: the Collaborative Study on the Genetics of Alcoholism. BMC Genet. 6 Suppl. 1: S5 (2005). *

• Kim HR, Rajaiah R, Wu QL, Satpute SR, Tan MT, Simon JE, Berman BM, Moudgil KD. Green tea protects rats against autoimmune arthritis by modulating disease-related immune events. J. Nutr. 138: 2111-2116 (2008). *

• Kim SC, Ferry GD. Inflammatory bowel diseases in pediatric and adolescent patients: clinical, therapeutic, and psychosocial considerations. Gastroenterology 126: 1550-1560 (2004). *

• Kim WR. Epidemiology of hepatitis B in the United States. Hepatology 49: S28-S34 (2009).

• Kim WR, Lindor KD, Locke GR 3rd, Therneau TM, Homburger HA, Batts KP, Yawn BP, Petz JL, Melton LJ 3rd, Dickson ER. Epidemiology and natural history of primary biliary cirrhosis in a US community. Gastroenterology 119: 1631-1636 (2000). *

• Kim YJ, Park JH, Kim I, Kim JO, Bae JS, Shin HD, Bae SC. Putative role of functional interferon regulatory factor 5 (IRF5) polymorphism in rheumatoid arthritis in a Korean population. J. Rheumatol. 35: 2106-2118 (2008). *

• Kimball AB, Kupper TS. Future perspectives/quo vadis psoriasis treatment? Immunology, pharmacogenomics, and epidemiology. Clin. Dermatol. 26: 554-561 (2008).

• Kimura Y, Takada T, Kawarada Y, Nimura Y, Hirata K, Sekimoto M, Yoshida M, Mayumi T, Wada K, Miura F, Yasuda H, Yamashita Y, Nagino M, Hirota M, Tanaka A, Tsuyuguchi T, Strasberg SM, Gadacz TR. Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines. J. Hepatobiliary Pancreat. Surg. 14: 15-26 (2007). *

• Kirsten H, Blume M, Emmrich F, Hunzelmann N, Mierau R, Rzepka R, Vaith P, Witte T, Melchers I, Ahnert P. No association between systemic sclerosis and C77G polymorphism in the human PTPRC (CD45) gene. J. Rheumatol. 35: 1817-1819 (2008).

• Kis J, Engelmann P, Farkas K, Richman G, Eck S, Lolley J, Jalahej H, Borowiec M, Kent SC, Treszl A, Orban T. Reduced CD4+ subset and Th1 bias of the human iNKT cells in type 1 diabetes mellitus. J. Leukoc. Biol. 81: 654-662 (2007). *

• Kitahora T, Utsunomiya T, Yokota A. Epidemiological study of ulcerative colitis in Japan: incidence and familial occurrence. The Epidemiology Group of the Research Committee of Inflammatory Bowel Disease in Japan. J. Gastroenterol. 30 Suppl. 8: 5-8 (1995).

• Kitauchi S, Nishi S, Nishioka S. Intestinal Behcet's disease: epidemiology, pathophysiology and potential of mesalazine. BioDrugs 13: 409-413 (2000).

• Klareskog L, Padyukov L, Lorentzen J, Alfredsson L. Mechanisms of disease: genetic susceptibility and environmental triggers in the development of rheumatoid arthritis. Nat. Clin. Pract. Rheumatol. 2: 425-433 (2006). *

• Klareskog L, Padyukov L, Ronnelid J, Alfredsson L. Genes, environment and immunity in the development of rheumatoid arthritis. Curr. Opin. Immunol. 18: 650-655 (2006).

• Klein AP, Hruban RH, Brune KA, Petersen GM, Goggins M. Familial pancreatic cancer. Cancer J. 7: 266-273 (2001).

• Kleinman RE, Baldassano RN, Caplan A, Griffiths AM, Heyman MB, Issenman RM, Lake AM. Nutrition support for pediatric patients with inflammatory bowel disease: a clinical report of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J. Pediatr. Gastroenterol. Nutr. 39: 15-27 (2004). *

• Kleiser C, Mensink GB, Scheidt-Nave C, Kurth BM. HuSKY: a healthy nutrition score based on food intake of children and adolescents in Germany. Br. J. Nutr. 102: 610-618 (2009). *

• Knigge KL. Inflammatory bowel disease. Clin. Cornerstone 4: 49-60 (2002).

• Knudsen VK, Hansen HS, Osterdal ML, Mikkelsen TB, Mu H, Olsen SF. Fish oil in various doses or flax oil in pregnancy and timing of spontaneous delivery: a randomised controlled trial. BJOG 113: 536-543 (2006). *

• Kobayashi M, Tsubono Y, Otani T, Hanaoka T, Sobue T, Tsugane S; JPHC Study Group. Fish, long-chain n-3 polyunsaturated fatty acids, and risk of colorectal cancer in middle-aged Japanese: the JPHC study. Nutr. Cancer 49: 32-40 (2004). *

• Kobayashi T, Hibi T. Concept, definition and epidemiology of inflammatory bowel diseases. Nippon Naika Gakkai Zasshi 98: 5-11 (2009).

• Kodama M, Kodama M. The autoimmune disease complex interstitial pneumonia/dermatomyositis in the light of endocrinology and cancer epidemiology. In Vivo 23: 353-356 (2009).

• Koehler RN, Walsh AM, Moqueet N, Currier JR, Eller MA, Eller LA, Wabwire-Mangen F, Michael NL, Robb ML, McCutchan FE, Kijak GH. High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR. Tissue Antigens 74: 73-80 (2009). *

• Koffeman GI, van Gemert WG, George EK, Veenendaal RA. Classification, epidemiology and aetiology. Best Pract. Res. Clin. Gastroenterol. 17: 879-893 (2003). *

• Koldingsnes W, Nossent H. Epidemiology of Wegener's granulomatosis in northern Norway. Arthritis Rheum. 43: 2481-2487 (2000). *

• Koletzko B, Demmelmair H, Schaeffer L, Illig T, Heinrich J. Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements. Nestle Nutr. Workshop Ser. Pediatr. Program 62: 35-49 (2008).

• Koletzko S. Epidemiology in pediatric inflammatory bowel disease. In: Walker-Smith JA, Lebenthal E, Branski D (eds), Pediatric and Inflammatory Bowel Disease: Perspective and Consequences. Pediatr. Adolesc. Med. Basel, Karger, vol 14, pp. 19-28 (2009). *

• Kollerits B, Coassin S, Kiechl S, Hunt SC, Paulweber B, Willeit J, Brandstatter A, Adams TD, Kronenberg F. A common variant in the adiponutrin gene influences liver enzyme levels. J. Med. Genet. Jun 18 [Epub ahead of print] (2009).

• Kompauer I, Demmelmair H, Koletzko B, Bolte G, Linseisen J, Heinrich J. Association of fatty acids in serum phospholipids with lung function and bronchial hyperresponsiveness in adults. Eur. J. Epidemiol. 23: 175-190 (2008). *

• Koralek DO, Peters U, Andriole G, Reding D, Kirsh V, Subar A, Schatzkin A, Hayes R, Leitzmann MF. A prospective study of dietary alpha-linolenic acid and the risk of prostate cancer (United States). Cancer Causes Control 17: 783-791 (2006). *

• Koralnik IJ. Progressive multifocal leukoencephalopathy revisited: has the disease outgrown its name? Ann. Neurol. 60: 162-173 (2006).

• Kornfeld D, Ekbom A, Ihre T. Is there an excess risk for colorectal cancer in patients with ulcerative colitis and concomitant primary sclerosing cholangitis? A population based study. Gut 41: 522-525 (1997). *

• Kornfeld D, Ekbom A, Ihre T. Survival and risk of cholangiocarcinoma in patients with primary sclerosing cholangitis. A population-based study. Scand. J. Gastroenterol. 32: 1042-1045 (1997).

• Koseki M, Maki Y, Matsukubo T, Ohashi Y, Tsubota K. Salivary flow and its relationship to oral signs and symptoms in patients with dry eyes. Oral. Dis. 10: 75-80 (2004). *

• Koshiol J, Gridley G, Engels EA, McMaster ML, Landgren O. Chronic immune stimulation and subsequent Waldenstrom macroglobulinemia. Arch. Intern. Med. 168: 1903-1909 (2008). *

• Koshiol J, Hildesheim A, Gonzalez P, Bratti MC, Porras C, Schiffman M, Herrero R, Rodriguez AC, Wacholder S, Yeager M, Chanock SJ, Burk RD, Wang SS. Common genetic variation in TP53 and risk of human papillomavirus persistence and progression to CIN3/cancer revisited. Cancer Epidemiol. Biomarkers Prev. 18: 1631-1637 (2009). *

• Kottgen A, Glazer NL, Dehghan A, Hwang SJ, Katz R, Li M, Yang Q, Gudnason V, Launer LJ, Harris TB, Smith AV, Arking DE, Astor BC, Boerwinkle E, Ehret GB, Ruczinski I, Scharpf RB, Ida Chen YD, de Boer IH, Haritunians T, Lumley T, et al. Multiple loci associated with indices of renal function and chronic kidney disease. Nat. Genet. 41: 712-717 (2009). *

• Koulentaki M, Moscandrea J, Dimoulios P, Chatzicostas C, Kouroumalis EA. Survival of anti-mitochondrial antibody-positive and -negative primary biliary cirrhosis patients on ursodeoxycholic acid treatment. Dig. Dis. Sci. 49: 1190-1195 (2004). *

• Kourosh AS, Miner A, Menter A. Psoriasis as the marker of underlying systemic disease. Skin Therapy Lett. 13: 1-5 (2008). *

• Koutros S, Berndt SI, Sinha R, Ma X, Chatterjee N, Alavanja MC, Zheng T, Huang WY, Hayes RB, Cross AJ. Xenobiotic metabolizing gene variants, dietary heterocyclic amine intake, and risk of prostate cancer. Cancer Res. 69: 1877-1884 (2009). *

• Kovacs M, Pak P, Pak G, Feher J. Small intestine capsule endoscopy in the diagnostics of coeliac disease. Orv. Hetil. 149: 1951-1955 (2008).

• Kraft P, Wacholder S, Cornelis MC, Hu FB, Hayes RB, Thomas G, Hoover R, Hunter DJ, Chanock S. Beyond odds ratios - communicating disease risk based on genetic profiles. Nat. Rev. Genet. 10: 264-269 (2009). *

• Kraggerud SM, Oldenburg J, Alnaes GI, Berg M, Kristensen VN, Fossa SD, Lothe RA. Functional glutathione S-transferase genotypes among testicular germ cell tumor survivors: associations with primary and post-chemotherapy tumor histology. Pharmacogenet. Genomics 19: 751-759 (2009).

• Kranke B, Trummer M, Brabek E, Komericki P, Turek TD, Aberer W. Etiologic and causative factors in perianal dermatitis: results of a prospective study in 126 patients. Wien. Klin. Wochenschr. 118: 90-94 (2006).

• Krause I, Weinberger A. Behcet's disease. Curr. Opin. Rheumatol. 20: 82-87 (2008).

• Kreimer-Erlacher H, Seidl H, Back B, Kerl H, Wolf P. High mutation frequency at Ha-ras exons 1-4 in squamous cell carcinomas from PUVA-treated psoriasis patients. Photochem. Photobiol. 74: 323-330 (2001).

• Kremers HM, McEvoy MT, Dann FJ, Gabriel SE. Heart disease in psoriasis. J. Am. Acad. Dermatol. 57: 347-354 (2007).

• Kristiansen OP, Karlsen AE, Larsen ZM, Johannesen J, Pociot F, Mandrup-Poulsen T; Danish IDDM Epidemiology and Genetics Group and Danish Study Group of IDDM in Childhood. Identification of a type 1 diabetes-associated CD4 promoter haplotype with high constitutive activity. Scand. J. Immunol. 59: 582-591 (2004). *

• Kronberger IE, Graziadei IW, Vogel W. Small bowel adenocarcinoma in Crohn's disease: a case report and review of literature. World J. Gastroenterol. 12: 1317-1320 (2006). *

• Krupp LB, Banwell B, Tenembaum S. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology 68: S7-S12 (2007).

• Kucukali CI, Aydin M, Ozkok E, Bilge E, Orhan N, Zengin A, Kara I. Do schizophrenia and bipolar disorders share a common disease susceptibility variant at the MMP3 gene? Prog. Neuropsychopharmacol. Biol. Psychiatry 33: 557-561 (2009).

• Kugathasan S, Judd RH, Hoffmann RG, Heikenen J, Telega G, Khan F, Weisdorf-Schindele S, San Pablo W Jr, Perrault J, Park R, Yaffe M, Brown C, Rivera-Bennett MT, Halabi I, Martinez A, Blank E, Werlin SL, Rudolph CD, Binion DG. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: a statewide population-based study. J. Pediatr. 143: 525-531 (2003). *

• Kuijper EJ, van den Berg RJ, Brazier JS. Comparison of molecular typing methods applied to Clostridium difficile. Methods Mol. Biol. 551: 159-171 (2009). *

• Kuiper EM, Hansen BE, de Vries RA, den Ouden-Muller JW, van Ditzhuijsen TJ, Haagsma EB, Houben MH, Witteman BJ, van Erpecum KJ, van Buuren HR, for the Dutch PBC study group. Improved prognosis of patients with primary biliary cirrhosis that have a biochemical response to ursodeoxycholic acid. Gastroenterology 136: 1281-1287 (2009). *

• Kuipers A, Zhang Y, Cauley JA, Nestlerode CS, Chu Y, Bunker CH, Patrick AL, Wheeler VW, Hoffman AR, Orwoll ES, Zmuda JM. Association of a high mobility group gene (HMGA2) variant with bone mineral density. Bone 45: 295-300 (2009). *

• Kumar A, Teuber SS, Gershwin ME. Why do people die of anaphylaxis? - a clinical review. Clin. Dev. Immunol. 12: 281-287 (2005). *

• Kundhal KK, Kundhal PS, Griffiths AM. Crohn’s disease in children. University of Toronto Medical Journal 78: 200-204 (2001). *

• Kunert K, Seiler M, Mashreghi MF, Klippert K, Schonemann C, Neumann K, Pratschke J, Reinke P, Volk HD, Kotsch K. KIR/HLA ligand incompatibility in kidney transplantation. Transplantation 84: 1527-1533 (2007).

• Kurbanov F, Tanaka Y, Mizokami M. Geographical and genetic diversity of the human hepatitis B virus. Hepatol. Res. 40: 14-30 (2010). *

• Kurd SK, Gelfand JM. The prevalence of previously diagnosed and undiagnosed psoriasis in US adults: results from NHANES 2003-2004. J. Am. Acad. Dermatol. 60: 218-224 (2009).

• Kure S, Nosho K, Baba Y, Irahara N, Shima K, Ng K, Meyerhardt JA, Giovannucci EL, Fuchs CS, Ogino S. Vitamin D receptor expression is associated with PIK3CA and KRAS mutations in colorectal cancer. Cancer Epidemiol. Biomarkers Prev. 18: 2765-2772 (2009). *

• Kuriki K, Hirose K, Matsuo K, Wakai K, Ito H, Kanemitsu Y, Hirai T, Kato T, Hamajima N, Takezaki T, Suzuki T, Saito T, Tanaka R, Tajima K. Meat, milk, saturated fatty acids, the Pro12Ala and C161T polymorphisms of the PPARgamma gene and colorectal cancer risk in Japanese. Cancer Sci. 97: 1226-1235 (2006). *

• Kuriki K, Hirose K, Wakai K, Matsuo K, Ito H, Suzuki T, Hiraki A, Saito T, Iwata H, Tatematsu M, Tajima K. Breast cancer risk and erythrocyte compositions of n-3 highly unsaturated fatty acids in Japanese. Int. J. Cancer 121: 377-385 (2007). *

• Kuriki K, Mutoh M, Tajima K, Wakabayashi K, Tatematsu M. Relationships between intestinal polyp formation and fatty acid levels in plasma, erythrocytes, and intestinal polyps in Min mice. Cancer Sci. 99: 2410-2416 (2008). *

• Kuriki K, Wakai K, Hirose K, Matsuo K, Ito H, Suzuki T, Saito T, Kanemitsu Y, Hirai T, Kato T, Tatematsu M, Tajima K. Risk of colorectal cancer is linked to erythrocyte compositions of fatty acids as biomarkers for dietary intakes of fish, fat, and Fatty acids. Cancer Epidemiol. Biomarkers Prev. 15: 1791-1798 (2006). *

• Kurina LM, Goldacre MJ, Yeates D, Gill LE. Depression and anxiety in people with inflammatory bowel disease. J. Epidemiol. Community Health 55: 716-720 (2001). *

• Kuwabara S. Guillain-Barre syndrome: epidemiology, pathophysiology and management. Drugs 64: 597-610 (2004).

• Kvien TK. Epidemiology and burden of illness of rheumatoid arthritis. Pharmacoeconomics 22: 1-12 (2004).

• Kwon HJ, Cote TR, Cuffe MS, Kramer JM, Braun MM. Case reports of heart failure after therapy with a tumor necrosis factor antagonist. Ann. Intern. Med. 138: 807-811 (2003). *

• Lacher M, Kappler R, Schroepf S, Berkholz S, Ballauff A, Bufler P, Baurecht H, von Schweinitz D, Koletzko S. Nuclear pregnane X receptor single nucleotide polymorphism (-25385C/T) is not associated with inflammatory bowel disease in pediatric patients. J. Pediatr. Gastroenterol. Nutr. 49: 147-150 (2009).

• Laffan AM, Bellantoni MF, Greenough WB 3rd, Zenilman JM. Burden of Clostridium difficile-associated diarrhea in a long-term care facility. J. Am. Geriatr. Soc. 54: 1068-1073 (2006).

• Lagerqvist C, Dahlbom I, Hansson T, Jidell E, Juto P, Olcen P, Stenlund H, Hernell O, Ivarsson A. Antigliadin immunoglobulin A best in finding celiac disease in children younger than 18 months of age. J. Pediatr. Gastroenterol. Nutr. 47: 428-435 (2008). *

• Laing AW, Pardi DS, Loftus EV Jr, Smyrk TC, Kammer PP, Tremaine WJ, Schleck CD, Harmsen WS, Zinsmeister AR, Melton LJ 3rd, Sandborn WJ. Microscopic colitis is not associated with cholecystectomy or appendectomy. Inflamm. Bowel Dis. 12: 708-711 (2006). *

• Lakatos L, Lakatos PL. Changes in the epidemiology of inflammatory bowel diseases. Orv. Hetil. 148: 223-228 (2007).

• Lakatos L, Lakatos PL. Is the incidence and prevalence of inflammatory bowel diseases increasing in Eastern Europe? Postgrad. Med. J. 82: 332-337 (2006). *

• Lakatos L, Mester G, Erdelyi Z, Balogh M, Szipocs I, Kamaras G, Lakatos PL. Epidemiology of inflammatory bowel diseases in Veszprem county of Western Hungary between 1977 and 2001. Orv. Hetil. 144: 1819-1827 (2003).

• Lakatos L, Mester G, Erdelyi Z, David G, Pandur T, Balogh M, Fischer S, Vargha P, Lakatos PL. Risk factors for ulcerative colitis-associated colorectal cancer in a Hungarian cohort of patients with ulcerative colitis: results of a population-based study. Inflamm. Bowel Dis. 12: 205-211 (2006). *

• Lakatos L, Mester G, Erdelyi Z, David G, Pandur T, Balogh M, Fischer S, Vargha P, Lakatos PL. Risk factors for ulcerative colitis associated colorectal cancers in a Hungarian cohort of ulcerative colitis patients. Orv. Hetil. 147: 175-181 (2006).

• Lakatos PL. Recent trends in the epidemiology of inflammatory bowel diseases: up or down? World J. Gastroenterol. 12: 6102-6108 (2006). *

• Lakatos PL. Environmental factors affecting inflammatory bowel disease: have we made progress? Dig. Dis. 27: 215-225 (2009).

• Lakatos PL, Fischer S, Lakatos L. Is the epidemiology of inflammatory bowel disease changing in Eastern Europe? Scand. J. Gastroenterol. 41: 870-872 (2006). *

• Lakeman P, Plass AM, Henneman L, Bezemer PD, Cornel MC, Ten Kate LP. Three-month follow-up of Western and non-Western participants in a study on preconceptional ancestry-based carrier couple screening for cystic fibrosis and hemoglobinopathies in the Netherlands. Genet. Med. 10: 820-830 (2008).

• Lamb RM, Zeggini E, M Abinun Et Al B, Thomson W, Donn R. Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis. Ann. Rheum. Dis. 64: 767-769 (2005). *

• Lambert JF, Nydegger UE. Geoepidemiology of autoimmune hemolytic anemia. Autoimmun. Rev. Nov 19 [Epub ahead of print] (2009).

• Lambert NC, Stevens AM, Tylee TS, Erickson TD, Furst DE, Nelson JL. From the simple detection of microchimerism in patients with autoimmune diseases to its implication in pathogenesis. Ann. N. Y. Acad. Sci. 945: 164-171 (2001). *

• Lambiase A, Rossano F, Del Pezzo M, Raia V, Sepe A, de Gregorio F, Catania MR. Sphingobacterium respiratory tract infection in patients with cystic fibrosis. BMC Res. Notes 2: 262 (2009). *

• Lamireau T, Monnereau S, Martin S, Marcotte JE, Winnock M, Alvarez F. Epidemiology of liver disease in cystic fibrosis: a longitudinal study. J. Hepatol. 41: 920-925 (2004). *

• Lammert F, Sauerbruch T. Genetics of gallstone disease. Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 16-18 (2006). *

• Lammi N, Karvonen M, Tuomilehto J. Do microbes have a causal role in type 1 diabetes? Med. Sci. Monit. 11: RA63-RA69 (2005). *

• Lamprecht P, Ahmadi-Simab K, Gross WL, Hellmich B. Rheumatology: part 3. Research news concerning epidemiology, diagnosis, and therapy of primary systemic vasculitides. Med. Klin. (Munich) 101: 212-225 (2006).

• Landgren O, Engels EA, Pfeiffer RM, Gridley G, Mellemkjaer L, Olsen JH, Kerstann KF, Wheeler W, Hemminki K, Linet MS, Goldin LR. Autoimmunity and susceptibility to Hodgkin lymphoma: a population-based case-control study in Scandinavia. J. Natl. Cancer Inst. 98: 1321-1330 (2006). *

• Landgren O, Gridley G, Check D, Caporaso NE, Morris Brown L. Acquired immune-related and inflammatory conditions and subsequent chronic lymphocytic leukaemia. Br. J. Haematol. 139: 791-798 (2007). *

• Landgren O, Linet MS, McMaster ML, Gridley G, Hemminki K, Goldin LR. Familial characteristics of autoimmune and hematologic disorders in 8,406 multiple myeloma patients: a population-based case-control study. Int. J. Cancer 118: 3095-3098 (2006). *

• Lane N. Osteoporosis - is there a rational approach to fracture prevention? Bull. Hosp. Jt. Dis. 64: 67-71 (2006).

• Lane SE, Watts R, Scott DG. Epidemiology of systemic vasculitis. Curr. Rheumatol. Rep. 7: 270-275 (2005).

• Langevin SM, Lin D, Matsuo K, Gao CM, Takezaki T, Stolzenberg-Solomon RZ, Vasavi M, Hasan Q, Taioli E. Review and pooled analysis of studies on MTHFR C677T polymorphism and esophageal cancer. Toxicol. Lett. 184: 73-80 (2009). *

• Langley RG, Krueger GG, Griffiths CE. Psoriasis: epidemiology, clinical features, and quality of life. Ann. Rheum. Dis. 64 Suppl. 2: ii18-ii23 (2005). *

• Lankarani KB, Masoompour SM, Masoompour MB, Malekzadeh R, Tabei SZ, Haghshenas M. Changing epidemiology of IPSID in Southern Iran. Gut 54: 311-312 (2005). *

• Lapidus A. The changing epidemiology of inflammatory bowel diseases. Acta Gastroenterol. Belg. 64: 155-159 (2001).

• Larkin EK, Cartier KC, Gray-McGuire C. A regression based transmission/disequilibrium test for binary traits: the power of joint tests for linkage and association. BMC Genet. 6 Suppl. 1: S95 (2005). *

• Laroni A, Calabrese M, Perini P, Albergoni MP, Ranzato F, Tiberio M, Battistin L, Gallo P. Multiple sclerosis and autoimmune diseases epidemiology and HLA-DR association in North-east Italy. J. Neurol. 253: 636-639 (2006). *

• Larrey D. Epidemiology and individual susceptibility to adverse drug reactions affecting the liver. Semin. Liver Dis. 22: 145-155 (2002).

• Larsen M, Mose H, Gislum M, Skriver MV, Jepsen P, Norgard B, Sorensen HT. Survival after colorectal cancer in patients with Crohn's disease: a nationwide population-based Danish follow-up study. Am. J. Gastroenterol. 102: 163-167 (2007). *

• Larsson SC, Giovannucci E, Wolk A. Methionine and vitamin B6 intake and risk of pancreatic cancer: a prospective study of Swedish women and men. Gastroenterology 132: 113-118 (2007). *

• Larsson SC, Kumlin M, Ingelman-Sundberg M, Wolk A. Dietary long-chain n-3 fatty acids for the prevention of cancer: a review of potential mechanisms. Am. J. Clin. Nutr. 79: 935-945 (2004). *

• Larsson SC, Wolk A. Coffee consumption and risk of liver cancer: a meta-analysis. Gastroenterology 132: 1740-1745 (2007). *

• Lashner BA. Epidemiology of inflammatory bowel disease. Gastroenterol. Clin. North Am. 24: 467-474 (1995).

• Lashner BA. Ulcerative colitis and colorectal cancer chemoprevention. Medscape (http://www.medscape.com/viewarticle/566843) (2008). *

• Lata J, Stiburek O, Kopacova M. Spontaneous bacterial peritonitis: a severe complication of liver cirrhosis. World J. Gastroenterol. 15: 5505-5510 (2009). *

• Lattka E, Illig T, Heinrich J, Koletzko B. FADS gene cluster polymorphisms: important modulators of fatty acid levels and their impact on atopic diseases. J. Nutrigenet. Nutrigenomics 2: 119-128 (2009).

• Lattka E, Illig T, Heinrich J, Koletzko B. Do FADS genotypes enhance our knowledge about fatty acid related phenotypes? Clin. Nutr. Nov 28 [Epub ahead of print] (2009).

• Lattka E, Illig T, Koletzko B, Heinrich J. Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism. Curr. Opin. Lipidol. Oct 3 [Epub ahead of print] (2009).

• Lauretani F, Maggio M, Pizzarelli F, Michelassi S, Ruggiero C, Ceda GP, Bandinelli S, Ferrucci L. Omega-3 and renal function in older adults. Curr. Pharm. Des. 15: 4149-4156 (2009).

• Lazaridis KN. Sclerosing cholangitis epidemiology and etiology. J. Gastrointest. Surg. 12: 417-419 (2008). *

• Lazaridis KN, Petersen GM. Genomics, genetic epidemiology, and genomic medicine. Clin. Gastroenterol. Hepatol. 3: 320-328 (2005). *

• Lazaridis KN, Talwalkar JA. Clinical epidemiology of primary biliary cirrhosis: incidence, prevalence, and impact of therapy. J. Clin. Gastroenterol. 41: 494-500 (2007).

• Lazo M, Selvin E, Clark JM. Brief communication: clinical implications of short-term variability in liver function test results. Ann. Intern. Med. 148: 348-352 (2008). *

• Leal J, Gregson DB, Ross T, Church DL, Laupland KB. Epidemiology of Clostridium species bacteremia in Calgary, Canada, 2000-2006. J. Infect. 57: 198-203 (2008).

• Lee CK, Jonas MM. Pediatric hepatobiliary disease. Curr. Opin. Gastroenterol. 23: 306-309 (2007).

• Lee CT, Adler AI, Forouhi NG, Luben R, Welch A, Khaw KT, Bingham S, Wareham NJ. Cross-sectional association between fish consumption and albuminuria: the European prospective investigation of Cancer-Norfolk study. Am. J. Kidney Dis. 52: 876-886 (2008).

• Lee DH, Jacobs DR Jr, Porta M. Hypothesis: a unifying mechanism for nutrition and chemicals as lifelong modulators of DNA hypomethylation. Environ. Health Perspect. 117: 1799-1802 (2009). *

• Lee JH, Slifman NR, Gershon SK, Edwards ET, Schwieterman WD, Siegel JN, Wise RP, Brown SL, Udall JN Jr, Braun MM. Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept. Arthritis Rheum. 46: 2565-2570 (2002). *

• Lee JK, Enns R. Review of idiopathic pancreatitis. World J. Gastroenterol. 13: 6296-6313 (2007). *

• Lee NM, Brady CW. Liver disease in pregnancy. World J. Gastroenterol. 15: 897-906 (2009). *

• Lee S, Jeong J, Majewski T, Scherer SE, Kim MS, Tuziak T, Tang KS, Baggerly K, Grossman HB, Zhou JH, Shen L, Bondaruk J, Ahmed SS, Samanta S, Spiess P, Wu X, Filipek S, McConkey D, Bar-Eli M, Issa JP, Benedict WF, Czerniak B. Forerunner genes contiguous to RB1 contribute to the development of in situ neoplasia. Proc. Natl. Acad. Sci. U.S.A. 104: 13732-13737 (2007). *

• Lee SA. Gene-diet interaction on cancer risk in epidemiological studies. J. Prev. Med. Public Health 42: 360-370 (2009). *

• Lee SA, Fowke JH, Lu W, Ye C, Zheng Y, Cai Q, Gu K, Gao YT, Shu XO, Zheng W. Cruciferous vegetables, the GSTP1 Ile105Val genetic polymorphism, and breast cancer risk. Am. J. Clin. Nutr. 87: 753-760 (2008). *

• Lee SO, Cheong HS, Park BL, Bae JS, Sim WC, Chun JY, Isbat M, Uh ST, Kim YH, Jang AS, Park CS, Shin HD. MYLK polymorphism associated with blood eosinophil level among asthmatic patients in a Korean population. Mol. Cells 27: 175-181 (2009). *

• Lefkowitch JH. Liver histopathology. Clin. Liver Dis. 6: xv-xix (2002). *

• Lehman DM, Richardson DK, Jenkinson CP, Hunt KJ, Dyer TD, Leach RJ, Arya R, Abboud HE, Blangero J, Duggirala R, Stern MP. P2 promoter variants of the hepatocyte nuclear factor 4alpha gene are associated with type 2 diabetes in Mexican Americans. Diabetes 56: 513-517 (2007). *

• Leirisalo-Repo M. Reactive arthritis. Scand. J. Rheumatol. 34: 251-259 (2005). *

• Leitzmann MF, Stampfer MJ, Michaud DS, Augustsson K, Colditz GC, Willett WC, Giovannucci EL. Dietary intake of n-3 and n-6 fatty acids and the risk of prostate cancer. Am. J. Clin. Nutr. 80: 204-216 (2004). *

• Lejeune O, Simonart T. Origin of threshold behaviour in psoriatic skin. Dermatology 217: 295-298 (2008).

• Lengyel G, Feher J. Intrahepatic cholestasis of pregnancy. Orv. Hetil. 145: 2103-2105 (2004).

• Leombruno JP, Einarson TR, Keystone EC. The safety of anti-tumor necrosis factor treatments in rheumatoid arthritis: meta and exposure adjusted pooled analyses of serious adverse events. Ann. Rheum. Dis. 68: 1136-1145 (2009).

• Leon H, Shibata MC, Sivakumaran S, Dorgan M, Chatterley T, Tsuyuki RT. Effect of fish oil on arrhythmias and mortality: systematic review. BMJ 337: a2931 (2008).

• Leong RW, Lau JY, Sung JJ. The epidemiology and phenotype of Crohn's disease in the Chinese population. Inflamm. Bowel Dis. 10: 646-651 (2004). *

• Lepage C, Bouvier AM, Phelip JM, Hatem C, Vernet C, Faivre J. Incidence and management of malignant digestive endocrine tumours in a well defined French population. Gut 53: 549-553 (2004). *

• Lerch MM. Anticipating disaster: the genetics of familial pancreatic cancer. Gut 55: 150-151 (2006). *

• Leshinsky-Silver E, Karban A, Dalal I, Eliakim R, Shirin H, Tzofi T, Boaz M, Levine A. Evaluation of the interleukin-23 receptor gene coding variant R381Q in pediatric and adult Crohn disease. J. Pediatr. Gastroenterol. Nutr. 45: 405-408 (2007). *

• Letko E, Gurcan HM, Papliodis GN, Christen W, Foster CS, Ahmed AR. Relative risk for cancer in mucous membrane pemphigoid associated with antibodies to the beta4 integrin subunit. Clin. Exp. Dermatol. 32: 637-641 (2007). *

• Leung PS, Shu SA, Kenny TP, Wu PY, Tao MH. Development and validation of gene therapies in autoimmune diseases: epidemiology to animal models. Autoimmun. Rev. Dec 22 [Epub ahead of print] (2009).

• Leung V, Stefanovic A, Sheppard D. Severe cerebral aspergillosis after liver transplant. Transpl. Infect. Dis. Sep 30 [Epub ahead of print] (2009). *

• Levine AJ, Figueiredo JC, Lee W, Poynter JN, Conti D, Duggan DJ, Campbell PT, Newcomb P, Martinez ME, Hopper JL, Le Marchand L, Baron JA, Limburg PJ, Ulrich CM, Haile RW. Genetic variability in the MTHFR gene and colorectal cancer risk using the colorectal cancer family registry. Cancer Epidemiol. Biomarkers Prev. 19: 89-100 (2010).

• Levine D, Gottlieb A. Evaluation and management of psoriasis: an internist's guide. Med. Clin. North Am. 93: 1291-1303 (2009).

• Levine RJ, Vatten LJ, Horowitz GL, Qian C, Romundstad PR, Yu KF, Hollenberg AN, Hellevik AI, Asvold BO, Karumanchi SA. Pre-eclampsia, soluble fms-like tyrosine kinase 1, and the risk of reduced thyroid function: nested case-control and population based study. BMJ 339: b4336 (2009). *

• Levitsky J, Miller J, Leventhal J, Huang X, Flaa C, Wang E, Tambur A, Burt RK, Gallon L, Mathew JM. The human "Treg MLR": immune monitoring for FOXP3+ T regulatory cell generation. Transplantation 88: 1303-1311 (2009).

• Levitt N. Diabetes in Africa: epidemiology, management and healthcare challenges. Heart 94: 1376-1382 (2008).

• Levy C, Lindor KD. Current management of primary biliary cirrhosis and primary sclerosing cholangitis. J. Hepatol. 38: S24-S37 (2003). *

• Levy C, Lindor KD. Primary sclerosing cholangitis: epidemiology, natural history, and prognosis. Semin. Liver Dis. 26: 22-30 (2006). *

• Levy DM, Ardoin SP, Schanberg LE. Neurocognitive impairment in children and adolescents with systemic lupus erythematosus. Nat. Clin. Pract. Rheumatol. 5: 106-114 (2009).

• Levy I, Grisaru-Soen G, Lerner-Geva L, Kerem E, Blau H, Bentur L, Aviram M, Rivlin J, Picard E, Lavy A, Yahav Y, Rahav G. Multicenter cross-sectional study of nontuberculous mycobacterial infections among cystic fibrosis patients, Israel. Emerg. Infect. Dis. 14: 378-384 (2008). *

• Lewis J. Dysplasia in IBD: diagnosis and clinical implications. Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, p. 46 (2006). *

• Lewis J. Biomarkers, surveillance strategies, chromoendoscopy medication-induced malignancies and chemoprevention (future). Inflamm. Bowel Dis. 12 Suppl. 3: S12 (2006).

• Lewis JD. How safe is immunomodulator therapy? Inflamm. Bowel Dis. 7: 178-179 (2001). *

• Lewis JD. Immunomodulators and the need for surgery in Crohn's disease: insufficient evidence to convict. Inflamm. Bowel Dis. 11: 1120-1122 (2005). *

• Lewis JD. Anti-TNF antibodies for Crohn's disease - in pursuit of the perfect clinical trial. N. Engl. J. Med. 357: 296-298 (2007). *

• Lewis JD, Abramson O, Pascua M, Liu L, Asakura LM, Velayos FS, Hutfless SM, Alison JE, Herrinton LJ. Timing of myelosuppression during thiopurine therapy for inflammatory bowel disease: implications for monitoring recommendations. Clin. Gastroenterol. Hepatol. 7: 1195-1201 (2009).

• Lewis JD, Bilker WB, Brensinger C, Deren JJ, Vaughn DJ, Strom BL. Inflammatory bowel disease is not associated with an increased risk of lymphoma. Gastroenterology 121: 1080-1087 (2001). *

• Lewis JD, Brensinger C. Agreement between GPRD smoking data: a survey of general practitioners and a population-based survey. Pharmacoepidemiol. Drug Saf. 13: 437-441 (2004). *

• Lewis JD, Lichtenstein GR, Deren JJ, Sands BE, Hanauer SB, Katz JA, Lashner B, Present DH, Chuai S, Ellenberg JH, Nessel L, Wu GD; Rosiglitazone for Ulcerative Colitis Study Group. Rosiglitazone for active ulcerative colitis: a randomized placebo-controlled trial. Gastroenterology 134: 688-695 (2008). *

• Lewis JD, Lichtenstein GR, Stein RB, Deren JJ, Judge TA, Fogt F, Furth EE, Demissie EJ, Hurd LB, Su CG, Keilbaugh SA, Lazar MA, Wu GD. An open-label trial of the PPAR-gamma ligand rosiglitazone for active ulcerative colitis. Am. J. Gastroenterol. 96: 3323-3328 (2001). *

• Lewis JD, Schoenfeld P, Lichtenstein GR. An evidence-based approach to studies of the natural history of gastrointestinal diseases: recurrence of symptomatic Crohn's disease after surgery. Clin. Gastroenterol. Hepatol. 1: 229-236 (2003). *

• Lewis NR, Logan RF, Hubbard RB, West J. No increase in risk of fracture, malignancy or mortality in dermatitis herpetiformis: a cohort study. Aliment. Pharmacol. Ther. 27: 1140-1147 (2008). *

• Lewis NR, Sanders DS, Logan RF, Fleming KM, Hubbard RB, West J. Cholesterol profile in people with newly diagnosed coeliac disease: a comparison with the general population and changes following treatment. Br. J. Nutr. 102: 509-513 (2009). *

• Lewis NR, Scott BB. Meta-analysis: deamidated gliadin peptide (DGP) antibody and tissue transglutaminase (tTG) antibody compared as screening tests for coeliac disease. Aliment. Pharmacol. Ther. 31: 73-81 (2010). *

• Li C, Liu Z, Wang LE, Gershenwald JE, Lee JE, Prieto VG, Duvic M, Grimm EA, Wei Q. Haplotype and genotypes of the VDR gene and cutaneous melanoma risk in non-Hispanic whites in Texas: a case-control study. Int. J. Cancer 122: 2077-2084 (2008). *

• Li C, Liu Z, Zhang Z, Strom SS, Gershenwald JE, Prieto VG, Lee JE, Ross MI, Mansfield PF, Cormier JN, Duvic M, Grimm EA, Wei Q. Genetic variants of the vitamin D receptor gene alter risk of cutaneous melanoma. J. Invest. Dermatol. 127: 276-280 (2007). *

• Li G, Yin W, Chamberlain R, Hewett-Emmett D, Roberts JN, Yang X, Lippman SM, Clifford JL. Identification and characterization of the human retinoid X receptor alpha gene promoter. Gene 372: 118-127 (2006). *

• Li J, Norgard B, Precht DH, Olsen J. Psychological stress and inflammatory bowel disease: a follow-up study in parents who lost a child in Denmark. Am. J. Gastroenterol. 99: 1129-1133 (2004). *

• Li LH, Li WX, Wu O, Zhang GQ, Pan HF, Li XP, Xu JH, Dai H, Ye DQ. Fas expression on peripheral blood lymphocytes in systemic lupus erythematosus: relation to the organ damage and lymphocytes apoptosis. Mol. Biol. Rep. 36: 2047-2052 (2009). *

• Li LH, Pan HF, Li WX, Li XP, Xu JH, Ye DQ. Study on clinical features and complications with systemic lupus erythematosus (SLE) activity in Chinese Han population. Clin. Rheumatol. 28: 1301-1307 (2009). *

• Li LH, Yuan H, Pan HF, Li WX, Li XP, Ye DQ. Role of the Fcgamma receptor IIIA-V/F158 polymorphism in susceptibility to systemic lupus erythematosus and lupus nephritis: a meta-analysis. Scand. J. Rheumatol. Jan 9 [Epub ahead of print] (2010). *

• Li WQ, Pan KF, Zhang Y, Zhang L, Ma JL, Zhou T, Li JY, Wang Z, Su Y, You WC. Relationship between RUNX3 expression and precancerous gastric lesions in high-risk population. Beijing Da Xue Xue Bao 41: 348-352 (2009).

• Li WQ, Zhang L, Ma JL, Zhang Y, Li JY, Pan KF, You WC. Association between genetic polymorphisms of DNA base excision repair genes and evolution of precancerous gastric lesions in a Chinese population. Carcinogenesis 30: 500-505 (2009). *

• Li XX, Liu JP, Cheng JQ, Han SH, Geng YJ, Wei S, Gao ST, Huang DN, Nie SF. Intercellular adhesion molecule-1 gene K469E polymorphism and ischemic stroke: a case-control study in a Chinese population. Mol. Biol. Rep. 36: 1565-1571 (2009). *

• Li Y, Zhu X, Huang Y, Xiong H. Mutational analysis of the binding of staphylococcal enterotoxin D to the T cell receptor Vbeta chain and major histocompatibility complex class II. Immunol. Lett. 105: 55-60 (2006).

• Liang KY, Chiu YF. Multipoint linkage disequilibrium mapping using case-control designs. Genet. Epidemiol. 29: 365-376 (2005).

• Liang X, Gao Y, Lam TK, Li Q, Falk C, Yang XR, Goldstein AM, Goldin LR. Identifying rheumatoid arthritis susceptibility genes using high-dimensional methods. BMC Proc. 3 Suppl. 7: S79 (2009). *

• Liang XS, Caporaso N, McMaster ML, Ng D, Landgren O, Yeager M, Chanock S, Goldin LR. Common genetic variants in candidate genes and risk of familial lymphoid malignancies. Br. J. Haematol. 146: 418-423 (2009). *

• Liangpunsakul S, Chalasani N. Treatment of nonalcoholic fatty liver disease. Curr. Treat. Options Gastroenterol. 6: 455-463 (2003).

• Liao S, Ruddle NH. Synchrony of high endothelial venules and lymphatic vessels revealed by immunization. J. Immunol. 177: 3369-3379 (2006). *

• Lieberman DA, Holub J, Eisen G, Kraemer D, Morris CD. Utilization of colonoscopy in the United States: results from a national consortium. Gastrointest. Endosc. 62: 875-883 (2005).

• Lilla C, Risch A, Verla-Tebit E, Hoffmeister M, Brenner H, Chang-Claude J. SULT1A1 genotype and susceptibility to colorectal cancer. Int. J. Cancer 120: 201-206 (2007). *

• Lim YS, Kim WR. The global impact of hepatic fibrosis and end-stage liver disease. Clin. Liver Dis. 12: 733-746, vii (2008).

• Limer KL, Tosh K, Bujac SR, McConnell R, Doherty S, Nyberg F, Zhang W, Doherty M, Muir KR, Maciewicz RA. Attempt to replicate published genetic associations in a large, well-defined osteoarthritis case-control population (the GOAL study). Osteoarthritis Cartilage 17: 782-789 (2009).

• Limsui D, Pardi DS, Camilleri M, Loftus Jr EV, Kammer PP, Tremaine WJ, Sandborn WJ. Symptomatic overlap between irritable bowel syndrome and microscopic colitis. Inflamm. Bowel Dis. 13: 175-181 (2007). *

• Lin CH, Jeng JS, Hsieh ST, Yip PK, Wu RM. Acute disseminated encephalomyelitis: a follow-up study in Taiwan. J. Neurol. Neurosurg. Psychiatry 78: 162-167 (2007). *

• Lin MS, Dai YS, Pwu RF, Chen YH, Chang NC. Risk estimates for drugs suspected of being associated with Stevens-Johnson syndrome and toxic epidermal necrolysis: a case-control study. Intern. Med. J. 35: 188-190 (2005). *

• Lin WY, Schaid DJ. Power comparisons between similarity-based multilocus association methods, logistic regression, and score tests for haplotypes. Genet. Epidemiol. 33: 183-197 (2009).

• Lindberg C, Andersen O, Vahlne A, Dalton M, Runmarker B. Epidemiological investigation of the association between infectious mononucleosis and multiple sclerosis. Neuroepidemiology 10: 62-65 (1991).

• Lingenhel A, Kollerits B, Schwaiger JP, Hunt SC, Gress R, Hopkins PN, Schoenborn V, Heid IM, Kronenberg F. Serum bilirubin levels, UGT1A1 polymorphisms and risk for coronary artery disease. Exp. Gerontol. 43: 1102-1107 (2008).

• Linskens RK, Mallant-Hent RC, Murillo LS, von Blomberg BME, Alizadeh BZ, Pena AS. Genetic and serological markers to identify phenotypic subgroups in a Dutch Crohn’s disease population. Dig. Liver Dis. 36: 29-34 (2004). *

• Lipozencic J. Keynote from Japan 5th Georg Rajka International Symposium on Atopic Dermatitis, Kyoto, May 11-13, 2008. Acta Dermatovenerol. Croat. 16: 168-169 (2008).

• Lipozencic J, Marinovic B. Desmoglein story from Masayuki Amagai teach us how to discover the beauty of nature. Acta Dermatovenerol. Croat. 15: 274-275 (2007).

• Lipsitch M, Bergstrom CT, Antia R. Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures. BMC Med. Genet. 4: 2 (2003). *

• Lipworth L, Bender TJ, Rossi M, Bosetti C, Negri E, Talamini R, Giacosa A, Franceschi S, McLaughlin JK, La Vecchia C. Dietary vitamin D intake and cancers of the colon and rectum: a case-control study in Italy. Nutr. Cancer 61: 70-75 (2009).

• Lipworth L, Tarone RE, McLaughlin JK. Silicone breast implants and connective tissue disease: an updated review of the epidemiologic evidence. Ann. Plast. Surg. 52: 598-601 (2004).

• Liu M, Worley S, Arrigain S, Aurora P, Ballmann M, Boyer D, Conrad C, Eichler I, Elidemir O, Goldfarb S, Mallory GB, Mogayzel PJ, Parakininkas D, Visner G, Sweet S, Faro A, Michaels M, Danziger-Isakov LA. Respiratory viral infections within one year after pediatric lung transplant. Transpl. Infect. Dis. 11: 304-312 (2009).

• Liu MH, Li J, Shen P, Husna B, Tai ES, Yong EL. A natural polymorphism in peroxisome proliferator-activated receptor-alpha hinge region attenuates transcription due to defective release of nuclear receptor corepressor from chromatin. Mol. Endocrinol. 22: 1078-1092 (2008). *

• Liu W, Cao WC, Zhang CY, Tian L, Wu XM, Habbema JD, Zhao QM, Zhang PH, Xin ZT, Li CZ, Yang H. VDR and NRAMP1 gene polymorphisms in susceptibility to pulmonary tuberculosis among the Chinese Han population: a case-control study. Int. J. Tuberc. Lung Dis. 8: 428-434 (2004).

• Liu Z, Calderon JI, Zhang Z, Sturgis EM, Spitz MR, Wei Q. Polymorphisms of vitamin D receptor gene protect against the risk of head and neck cancer. Pharmacogenet. Genomics 15: 159-165 (2005).

• Liu-Mares W, Sun Z, Bamlet WR, Atkinson EJ, Fridley BL, Slager SL, de Andrade M, Goode EL. Analysis of variation in NF-kappaB genes and expression levels of NF-kappaB-regulated molecules. BMC Proc. 1 Suppl. 1: S126 (2007). *

• Llorca J, Lopez-Diaz MJ, Gonzalez-Juanatey C, Ollier WE, Martin J, Gonzalez-Gay MA. Persistent chronic inflammation contributes to the development of cancer in patients with rheumatoid arthritis from a defined population of Northwestern Spain. Semin. Arthritis Rheum. 37: 31-38 (2007). *

• Loeve M, Lequin MH, de Bruijne M, Hartmann IJ, Gerbrands K, van Straten M, Hop WC, Tiddens HA. Cystic fibrosis: are volumetric ultra-low-dose expiratory CT scans sufficient for monitoring related lung disease? Radiology 253: 223-229 (2009).

• Loftus CG, Loftus EV Jr, Harmsen WS, Zinsmeister AR, Tremaine WJ, Melton LJ 3rd, Sandborn WJ. Update on the incidence and prevalence of Crohn's disease and ulcerative colitis in Olmsted County, Minnesota, 1940-2000. Inflamm. Bowel Dis. 13: 254-261 (2007). *

• Loftus EV. Management of extraintestinal manifestations and other complications of inflammatory bowel disease. Curr. Gastroenterol. Rep. 6: 506-513 (2004).

• Loftus EV Jr. Epidemiology and risk factors for colorectal dysplasia and cancer in ulcerative colitis. Gastroenterol. Clin. North Am. 35: 517-531 (2006).

• Loftus EV Jr. Clinical epidemiology of inflammatory bowel disease: incidence, prevalence, and environmental influences. Gastroenterology 126: 1504-1517 (2004). *

• Loftus EV Jr. The new epidemiology of IBD: a unique phenomenon or part of a global trend? Inflamm. Bowel Dis. 12 Suppl. 3: S1-S2 (2006).

• Loftus EV Jr, Sandborn WJ. Epidemiology of inflammatory bowel disease. Gastroenterol. Clin. North Am. 31: 1-20 (2002).

• Loftus EV Jr, Schoenfeld P, Sandborn WJ. The epidemiology and natural history of Crohn's disease in population-based patient cohorts from North America: a systematic review. Aliment. Pharmacol. Ther. 16: 51-60 (2002). *

• Logan I, Bowlus CL. The geoepidemiology of autoimmune intestinal diseases. Autoimmun. Rev. Nov 7 [Epub ahead of print] (2009).

• Logan RF. Smoking, use of oral contraceptives, and medical induction of remission were risk factors for relapse in Crohn's disease. Gut 44: 311-312 (1999). *

• Logan RF. Antibiotics and flare of inflammatory bowel disease: threat or therapy? Nat. Clin. Pract. Gastroenterol. Hepatol. 2: 446-447 (2005). *

• Logan RF. Malignancy in unrecognised coeliac disease: a nail in the coffin for mass screening? Gut 58: 618-619 (2009).

• Logan RF, Grainge MJ, Shepherd VC, Armitage NC, Muir KR; UKCAP Trial Group. Aspirin and folic acid for the prevention of recurrent colorectal adenomas. Gastroenterology 134: 29-38 (2008). *

• Logan RF, Skelly MM. Smoking and hepato-biliary disease. Eur. J. Gastroenterol. Hepatol. 12: 863-867 (2000).

• Loh YH, Mitrou PN, Bowman R, Wood A, Jeffery H, Luben RN, Lentjes MA, Khaw KT, Rodwell SA. MGMT Ile143Val polymorphism, dietary factors and the risk of breast, colorectal and prostate cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC)-Norfolk study. DNA Repair (Amst.) Jan 20 [Epub ahead of print] (2010).

• Lok KH, Hung HG, Ng CH, Kwong KC, Yip WM, Lau SF, Li KK, Li KF, Szeto ML. Epidemiology and clinical characteristics of ulcerative colitis in Chinese population: experience from a single center in Hong Kong. J. Gastroenterol. Hepatol. 23: 406-410 (2008). *

• Lok KH, Hung HG, Ng CH, Li KK, Li KF, Szeto ML. The epidemiology and clinical characteristics of Crohn's disease in the Hong Kong Chinese population: experiences from a regional hospital. Hong Kong Med. J. 13: 436-441 (2007). *

• Long MD, Porter CQ, Sandler RS, Kappelman MD. Suboptimal rates of cervical testing among women with inflammatory bowel disease. Clin. Gastroenterol. Hepatol. 7: 549-553 (2009).

• Longobardi T, Bernstein CN. Health care resource utilization in inflammatory bowel disease. Clin. Gastroenterol. Hepatol. 4: 731-743 (2006).

• Longstreth WT Jr, Ton TG, Koepsell T, Gersuk VH, Hendrickson A, Velde S. Prevalence of narcolepsy in King County, Washington, USA. Sleep Med. 10: 422-426 (2009).

• Lophatananon A, Archer J, Easton D, Pocock R, Dearnaley D, Guy M, Kote-Jarai Z, O'Brien L, Wilkinson RA, Hall AL, Sawyer E, Page E, Liu JF, Barratt S, Rahman AA; The UK Genetic Prostate Cancer Study Collaborators. Dietary fat and early-onset prostate cancer risk. Br. J. Nutr. Jan 19 [Epub ahead of print] (2010). *

• Lord PA, Farragher TM, Lunt M, Watson KD, Symmons DP, Hyrich KL; on behalf of the BSR Biologics Register. Predictors of response to anti-TNF therapy in ankylosing spondylitis: results from the British Society for Rheumatology Biologics Register. Rheumatology (Oxford) 49: 563-570 (2010).

• Louis-Jacques O, Perman JA. Disorders of the stomach and duodenum in children. Curr. Opin. Gastroenterol. 15: 516-520 (1999).

• Lowe AJ, Thien FC, Stoney RM, Bennett CM, Hosking CS, Hill DJ, Carlin JB, Abramson MJ, Dharmage SC. Associations between fatty acids in colostrum and breast milk and risk of allergic disease. Clin. Exp. Allergy 38: 1745-1751 (2008). *

• Lowe AM, Roy PO, B-Poulin M, Michel P, Bitton A, St-Onge L, Brassard P. Epidemiology of Crohn's disease in Quebec, Canada. Inflamm. Bowel Dis. 15: 429-435 (2009). *

• Lowe AM, Yansouni CP, Behr MA. Causality and gastrointestinal infections: Koch, Hill, and Crohn's. Lancet Infect. Dis. 8: 720-726 (2008).

• Lowichik A, Book L. Pediatric celiac disease: clinicopathologic and genetic aspects. Pediatr. Dev. Pathol. 6: 470-483 (2003).

• Lu JC, Coca SG, Patel UD, Cantley L, Parikh CR; Translational Research Investigating Biomarkers and Endpoints for Acute Kidney Injury (TRIBE-AKI) Consortium. Searching for genes that matter in acute kidney injury: a systematic review. Clin. J. Am. Soc. Nephrol. 4: 1020-1031 (2009).

• Lu YJ, Forte S, Thompson CM, Anderson PW, Malley R. Protection against pneumococcal colonization and fatal pneumonia by a trivalent conjugate of a fusion protein with the cell wall polysaccharide. Infect. Immun. 77: 2076-2083 (2009). *

• Lucas RM, Ponsonby AL. Considering the potential benefits as well as adverse effects of sun exposure: can all the potential benefits be provided by oral vitamin D supplementation? Prog. Biophys. Mol. Biol. 92: 140-149 (2006). *

• Lucas RM, Ponsonby AL, Pasco JA, Morley R. Future health implications of prenatal and early-life vitamin D status. Nutr. Rev. 66: 710-720 (2008). *

• Lucas RM, Repacholi MH, McMichael AJ. Is the current public health message on UV exposure correct? Bull. World Health Organ. 84: 485-491 (2006).

• Lucidi V, Alghisi F, Raia V, Russo B, Valmarana L, Valmarana R, Coruzzo A, Beschi S, Dester S, Rinaldi D, Maglieri M, Guidotti ML, Ravaioli E, Pesola M, De Alessandri A, Padoan R, Grynzich L, Ratclif L, Repetto T, Ambroni M, Provenzano E, Tozzi AE, et al. Growth assessment of paediatric patients with CF comparing different auxologic indicators: a multicentre Italian study. J. Pediatr. Gastroenterol. Nutr. 49: 335-342 (2009).

• Ludajic K, Rosenmayr A, Fae I, Fischer GF, Balavarca Y, Bickeboller H, Kalhs P, Greinix HT. Association of HLA-E polymorphism with the outcome of hematopoietic stem-cell transplantation with unrelated donors. Transplantation 88: 1227-1228 (2009).

• Ludvigsson JF, Askling J, Ekbom A, Montgomery SM. Diagnosis underlying appendectomy and coeliac disease risk. Dig. Liver Dis. 38: 823-828 (2006).

• Ludvigsson JF, Elfstrom P, Broome U, Ekbom A, Montgomery SM. Celiac disease and risk of liver disease: a general population-based study. Clin. Gastroenterol. Hepatol. 5: 63-69.e1 (2007).

• Ludvigsson JF, Montgomery SM, Ekbom A. Risk of pancreatitis in 14,000 individuals with celiac disease. Clin. Gastroenterol. Hepatol. 5: 1347-1353 (2007).

• Ludvigsson JF, Montgomery SM, Ekbom A. Smoking and celiac disease: a population-based cohort study. Clin. Gastroenterol. Hepatol. 3: 869-874 (2005).

• Ludvigsson JF, Montgomery SM, Olen O, Ekbom A, Ludvigsson J, Fored M. Coeliac disease and risk of renal disease - a general population cohort study. Nephrol. Dial. Transplant. 21: 1809-1815 (2006). *

• Ludvigsson JF, Olsson T, Ekbom A, Montgomery SM. A population-based study of coeliac disease, neurodegenerative and neuroinflammatory diseases. Aliment. Pharmacol. Ther. 25: 1317-1327 (2007). *

• Ludvigsson JF, Reutfors J, Osby U, Ekbom A, Montgomery SM. Coeliac disease and risk of mood disorders. A general population-based cohort study. J. Affect. Disord. 99: 117-126 (2007).

• Luis Rodriguez-Tudela J, Berenguer J, Guarro J, Serda Kantarcioglu A, Horre R, Sybren De Hoog G, Cuenca-Estrella M. Epidemiology and outcome of Scedosporium prolificans infection, a review of 162 cases. Med. Mycol. 47: 359-370 (2009). *

• Lusis AJ, Attie AD, Reue K. Metabolic syndrome: from epidemiology to systems biology. Nat. Rev. Genet. 9: 819-830 (2008). *

• Lutsey PL, Steffen LM, Virnig BA, Folsom AR. Diet and incident venous thromboembolism: the Iowa Women's Health study. Am. Heart J. 157: 1081-1087 (2009).

• Luxon BA. Autoimmune hepatitis: diagnosis, treatment, and prognosis. Curr. Gastroenterol. Rep. 8: 83-88 (2006).

• Ma X, Qi X, Chen C, Lin H, Xiong H, Li Y, Jiang J. Association between CYP19 polymorphisms and breast cancer risk: results from 10,592 cases and 11,720 controls. Breast Cancer Res. Treat. Jan 6 [Epub ahead of print] (2010). *

• Macaubas C, Nguyen K, Milojevic D, Park JL, Mellins ED. Oligoarticular and polyarticular JIA: epidemiology and pathogenesis. Nat. Rev. Rheumatol. 5: 616-626 (2009).

• Macchia A, Monte S, Pellegrini F, Romero M, Ferrante D, Doval H, D'Ettorre A, Maggioni AP, Tognoni G. Omega-3 fatty acid supplementation reduces one-year risk of atrial fibrillation in patients hospitalized with myocardial infarction. Eur. J. Clin. Pharmacol. 64: 627-634 (2008). *

• MacFaul GR, Chapman RW. Sclerosing cholangitis. Curr. Opin. Gastroenterol. 21: 348-353 (2005).

• Macfaul GR, Chapman RW. Sclerosing cholangitis. Curr. Opin. Gastroenterol. 22: 288-293 (2006).

• MacFaul GR, Chapman RW. Sclerosing cholangitis. Curr. Opin. Gastroenterol. 20: 275-280 (2004).

• MacGregor A, Ollier W, Thomson W, Jawaheer D, Silman A. HLA-DRB1*0401/0404 genotype and rheumatoid arthritis: increased association in men, young age at onset, and disease severity. J. Rheumatol. 22: 1032-1036 (1995).

• MacGregor HS, Latiwonk QI. Complex role of gamma-herpesviruses in multiple sclerosis and infectious mononucleosis. Neurol. Res. 15: 391-394 (1993).

• Macgregor S, Hottenga JJ, Lind PA, Suchiman HE, Willemsen G, Slagboom PE, Montgomery GW, Martin NG, Visscher PM, Boomsma DI. Vitamin D receptor gene polymorphisms have negligible effect on human height. Twin Res. Hum. Genet. 11: 488-494 (2008).

• MacIntyre CR, McIntyre PB. MMR, autism and inflammatory bowel disease: responding to patient concerns using an evidence-based framework. Med. J. Aust. 175: 127-128 (2001).

• Mackey AC, Green L, Amand KS, Avigan M. Sodium phosphate tablets and acute phosphate nephropathy. Am. J. Gastroenterol. 104: 1903-1906 (2009). *

• Magadmi ME, Ahmad Y, Turkie W, Yates AP, Sheikh N, Bernstein RM, Durrington PN, Laing I, Bruce IN. Hyperinsulinemia, insulin resistance, and circulating oxidized low density lipoprotein in women with systemic lupus erythematosus. J. Rheumatol. 33: 50-56 (2006). *

• Maggini V, Buda G, Martino A, Presciuttini S, Galimberti S, Orciuolo E, Barale R, Petrini M, Rossi AM. MDR1 diplotypes as prognostic markers in multiple myeloma. Pharmacogenet. Genomics 18: 383-389 (2008).

• Maggiore G, Sciveres M. Autoimmune hepatitis: a childhood disease. Current Pediatric Reviews 1: 73-90 (2005). *

• Maggs JR, Chapman RW. An update on primary sclerosing cholangitis. Curr. Opin. Gastroenterol. 24: 377-383 (2008).

• Maggs JR, Chapman RW. Sclerosing cholangitis. Curr. Opin. Gastroenterol. 23: 310-316 (2007).

• Mahajan R, El-Omar EM, Lissowska J, Grillo P, Rabkin CS, Baccarelli A, Yeager M, Sobin LH, Zatonski W, Channock SJ, Chow WH, Hou L. Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population. Jpn. J. Clin. Oncol. 38: 626-633 (2008).

• Mahr AD, Neogi T, Merkel PA. Epidemiology of Wegener's granulomatosis: lessons from descriptive studies and analyses of genetic and environmental risk determinants. Clin. Exp. Rheumatol. 24: S82-S91 (2006).

• Maiden MC. Putting leprosy on the map. Nat. Genet. 41: 1264-1266 (2009). *

• Maisonneuve P, Lowenfels AB, Mullhaupt B, Cavallini G, Lankisch PG, Andersen JR, Dimagno EP, Andren-Sandberg A, Domellof L, Frulloni L, Ammann RW. Cigarette smoking accelerates progression of alcoholic chronic pancreatitis. Gut 54: 510-514 (2005). *

• Maisonneuve P, Marshall BC, Lowenfels AB. Risk of pancreatic cancer in patients with cystic fibrosis. Gut 56: 1327-1328 (2007). *

• Maitland-van der Zee AH, Klungel OH, Stricker BH, Monique Verschuren WM, Kastelein JJ, Leufkens HG, de Boer A. Genetic polymorphisms: importance for response to HMG-CoA reductase inhibitors. Atherosclerosis 163: 213-222 (2002).

• Maitland-van der Zee AH, Peters BJ, Lynch AI, Boerwinkle E, Arnett DK, Cheng S, Davis BR, Leiendecker-Foster C, Ford CE, Eckfeldt JH. The effect of nine common polymorphisms in coagulation factor genes (F2, F5, F7, F12 and F13 ) on the effectiveness of statins: the GenHAT study. Pharmacogenet. Genomics 19: 338-344 (2009).

• Makris AT, Gelone S. Clostridium difficile in the long-term care setting. J. Am. Med. Dir. Assoc. 8: 290-299 (2007).

• Maliarik MJ, Chen KM, Sheffer RG, Rybicki BA, Major ML, Popovich J Jr, Iannuzzi MC. The natural resistance-associated macrophage protein gene in African Americans with sarcoidosis. Am. J. Respir. Cell Mol. Biol. 22: 672-675 (2000). *

• Mamula P, Markowitz JE, Baldassano RN. Inflammatory bowel disease in early childhood and adolescence: special considerations. Gastroenterol. Clin. North Am. 32: 967-995, viii (2003).

• Mandayam S, Jamal MM, Morgan TR. Epidemiology of alcoholic liver disease. Semin. Liver Dis. 24: 217-232 (2004).

• Mandhyan DD, Kim-Howard X, Gaines M, Nath SK. A genome-wide ordered-subset linkage analysis for rheumatoid arthritis. BMC Proc. 1 Suppl. 1: S101 (2007). *

• Mangione RA, Patel PN. Caring for patients with celiac disease: the role of the pharmacist. J. Am. Pharm. Assoc. 48: e125-e135 (2003).

• Manguso F, Sanges M, Staiano T, Gargiulo S, Nastro P, Gargano D, Somma P, Mansueto G, Peluso R, Scarpa R, D'Armiento FP, Astarita C, Ayala F, Renda A, Mazzacca G, D'Arienzo A. Cigarette smoking and appendectomy are risk factors for extraintestinal manifestations in ulcerative colitis. Am. J. Gastroenterol. 99: 327-334 (2004). *

• Mao C, Pan H, Chen Q, Wang X, Ye D, Qiu L. Association between Fc receptor-like 3 C169T polymorphism and risk of systemic lupus erythematosus: a meta-analysis. Mol. Biol. Rep. Jun 30 [Epub ahead of print] (2009). *

• Mariani SM. Genes and autoimmune diseases - a complex inheritance. MedGenMed. 6: 18 (2004). *

• Marker-Hermann E, Behrens F. Psoriatic arthritis: treatment outcome parameters. Z. Rheumatol. 68: 16-22 (2009).

• Markowitz JE, Mamula P, Delrosario JF, Baldassano RN, Lewis JD, Jawad AF, Culton K, Strom BL. Patterns of complementary and alternative medicine use in a population of pediatric patients with inflammatory bowel disease. Inflamm. Bowel Dis. 10: 599-605 (2004). *

• Marks MA, Gravitt PE, Burk RR, Studentsov Y, Farzadegan H, Klein SL. Progesterone and 17beta-estradiol enhance regulatory responses to HPV 16 VLP in peripheral blood mononuclear cells from healthy women. Clin. Vaccine Immunol. Feb 3 [Epub ahead of print] (2010). *

• Marra C. Rheumatoid arthritis: a primer for pharmacists. Am. J. Health Syst. Pharm. 63: S4-S10 (2006).

• Marshall JK, Thabane M, Garg AX, Clark WF, Salvadori M, Collins SM; Walkerton Health Study Investigators. Incidence and epidemiology of irritable bowel syndrome after a large waterborne outbreak of bacterial dysentery. Gastroenterology 131: 445-450 (2006). *

• Martin A, Lemon SM. Hepatitis A virus: from discovery to vaccines. Hepatology 43: S164-S172 (2006). *

• Martin K, Borgel D, Lerolle N, Feys HB, Trinquart L, Vanhoorelbeke K, Deckmyn H, Legendre P, Diehl JL, Baruch D. Decreased ADAMTS-13 (a disintegrin-like and metalloprotease with thrombospondin type 1 repeats) is associated with a poor prognosis in sepsis-induced organ failure. Crit. Care Med. 35: 2375-2382 (2007).

• Martin S. Against the grain: an overview of celiac disease. J. Am. Acad. Nurse Pract. 20: 243-250 (2008).

• Martinetti M, Biagi F, Badulli C, Feurle GE, Muller C, Moos V, Schneider T, Marth T, Marchese A, Trotta L, Sachetto S, Pasi A, De Silvestri A, Salvaneschi L, Corazza GR. The HLA alleles DRB1*13 and DQB1*06 are associated to Whipple's disease. Gastroenterology 136: 2289-2294 (2009). *

• Martínez Díaz-Guerra G, Hawkins Carranza F. Concept, etiology and epidemiology of primary hyperparathyroidism. Endocrinol. Nutr. 56 S1: 2-7 (2009).

• Martinez ME, Thompson P, Jacobs ET, Giovannucci E, Jiang R, Klimecki W, Alberts DS. Dietary factors and biomarkers involved in the methylenetetrahydrofolate reductase genotype-colorectal adenoma pathway. Gastroenterology 131: 1706-1716 (2006). *

• Martinez-Abundis E, Reynoso-von Drateln C, Hernandez-Salazar E, Gonzalez-Ortiz M. Effect of etanercept on insulin secretion and insulin sensitivity in a randomized trial with psoriatic patients at risk for developing type 2 diabetes mellitus. Arch. Dermatol. Res. 299: 461-465 (2007). *

• Martinez-Salmeron JF, Rodrigo M, de Teresa J, Nogueras F, Garcia-Montero M, de Sola C, Salmeron J, Caballero M. Epidemiology of inflammatory bowel disease in the Province of Granada, Spain: a retrospective study from 1979 to 1988. Gut 34: 1207-1209 (1993). *

• Martyn CN, Cruddas M, Compston DA. Symptomatic Epstein-Barr virus infection and multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 56: 167-168 (1993).

• Masala G, Bagnoli S, Ceroti M, Saieva C, Trallori G, Zanna I, D'Albasio G, Palli D. Divergent patterns of total and cancer mortality in ulcerative colitis and Crohn's disease patients: the Florence IBD study 1978-2001. Gut 53: 1309-1313 (2004). *

• Maschmeyer G, Calandra T, Singh N, Wiley J, Perfect J. Invasive mould infections: a multi-disciplinary update. Med. Mycol. 47: 571-583 (2009).

• Masi AT, Medsger TA Jr. A new look at the epidemiology of ankylosing spondylitis and related syndromes. Clin. Orthop. Relat. Res. 143: 15-29 (1979).

• Matheson MC, Ellis JA, Raven J, Walters EH, Abramson MJ. Association of IL8, CXCR2 and TNF-alpha polymorphisms and airway disease. J. Hum. Genet. 51: 196-203 (2006). *

• Matsukura H, Ikeda S, Yoshimura N, Takazoe M, Muramatsu M. Genetic polymorphisms of tumour necrosis factor receptor superfamily 1A and 1B affect responses to infliximab in Japanese patients with Crohn's disease. Aliment. Pharmacol. Ther. 27: 765-770 (2008). *

• Matsuo K, Hamajima N, Hirai T, Kato T, Inoue M, Takezaki T, Tajima K. Methionine synthase reductase gene A66G polymorphism is associated with risk of colorectal cancer. Asian Pac. J. Cancer Prev. 3: 353-359 (2002).

• Matsuo K, Ito H, Wakai K, Hirose K, Saito T, Suzuki T, Kato T, Hirai T, Kanemitsu Y, Hamajima H, Tajima K. One-carbon metabolism related gene polymorphisms interact with alcohol drinking to influence the risk of colorectal cancer in Japan. Carcinogenesis 26: 2164-2171 (2005). *

• Matsuo K, Wakai K, Hirose K, Ito H, Saito T, Suzuki T, Kato T, Hirai T, Kanemitsu Y, Hamajima H, Tajima K. A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in Japan. Carcinogenesis 27: 1018-1023 (2006). *

• Matsuo K, Wakai K, Hirose K, Ito H, Saito T, Tajima K. Alcohol dehydrogenase 2 His47Arg polymorphism influences drinking habit independently of aldehyde dehydrogenase 2 Glu487Lys polymorphism: analysis of 2,299 Japanese subjects. Cancer Epidemiol. Biomarkers Prev. 15: 1009-1013 (2006). *

• Mavragani CP, Moutsopoulos HM. The geoepidemiology of Sjogren's syndrome. Autoimmun. Rev. Nov 7 [Epub ahead of print] (2009).

• McCarty MF. Nutraceutical resources for diabetes prevention - an update. Med. Hypotheses 64: 151-158 (2005).

• McClean KM, Kee F, Young IS, Elborn JS. Obesity and the lung: 1 - epidemiology. Thorax 63: 649-654 (2008).

• McClure A, Lunt M, Eyre S, Ke X, Thomson W, Hinks A, Bowes J, Gibbons L, Plant D, Wilson AG, Marinou I, Morgan AW, Emery P; BIRAC consortium, Steer S, Hocking LJ, Reid DM, Wordsworth P, Harrison P, Worthington J, Barton A. Investigating the viability of genetic screening/testing for RA susceptibility using combinations of five confirmed risk loci. Rheumatology (Oxford) 48: 1369-1374 (2009). *

• McCullough ML, Bostick RM, Mayo TL. Vitamin D gene pathway polymorphisms and risk of colorectal, breast, and prostate cancer. Annu. Rev. Nutr. 29: 111-132 (2009). *

• McCullough ML, Robertson AS, Chao A, Jacobs EJ, Stampfer MJ, Jacobs DR, Diver WR, Calle EE, Thun MJ. A prospective study of whole grains, fruits, vegetables and colon cancer risk. Cancer Causes Control 14: 959-970 (2003). *

• McDonagh AJ, Tazi-Ahnini R. Epidemiology and genetics of alopecia areata. Clin. Exp. Dermatol. 27: 405-409 (2002). *

• McEntee MF, Whelan J. Dietary polyunsaturated fatty acids and colorectal neoplasia. Biomed. Pharmacother. 56: 380-387 (2002).

• McFarland LV. Renewed interest in a difficult disease: Clostridium difficile infections - epidemiology and current treatment strategies. Curr. Opin. Gastroenterol. 25: 24-35 (2009).

• McFarland LV. Update on the changing epidemiology of Clostridium difficile-associated disease. Nat. Clin. Pract. Gastroenterol. Hepatol. 5: 40-48 (2008). *

• McFarland LV. Antibiotic-associated diarrhea: epidemiology, trends and treatment. Future Microbiol. 3: 563-578 (2008).

• McFarland LV, Surawicz CM, Rubin M, Fekety R, Elmer GW, Greenberg RN. Recurrent Clostridium difficile disease: epidemiology and clinical characteristics. Infect. Control Hosp. Epidemiol. 20: 43-50 (1999). *

• McFaul CD, Greenhalf W, Earl J, Howes N, Neoptolemos JP, Kress R, Sina-Frey M, Rieder H, Hahn S, Bartsch DK. Anticipation in familial pancreatic cancer. Gut 55: 252-258 (2006). *

• McGlynn KA, Sakoda LC, Hu Y, Schoen RE, Bresalier RS, Yeager M, Chanock S, Hayes RB, Buetow KH. Hemochromatosis gene mutations and distal adenomatous colorectal polyps. Cancer Epidemiol. Biomarkers Prev. 14: 158-163 (2005). *

• McGlynn KA, Tarone RE, El-Serag HB. A comparison of trends in the incidence of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in the United States. Cancer Epidemiol. Biomarkers Prev. 15: 1198-1203 (2006). *

• McGowan CE, Lagares-Garcia JA, Bhattacharya B. Retained capsule endoscope leading to the identification of small bowel adenocarcinoma in a patient with undiagnosed Crohn disease. Ann. Diagn. Pathol. 13: 390-393 (2009).

• McKay JD, McCullough ML, Ziegler RG, Kraft P, Saltzman BS, Riboli E, Barricarte A, Berg CD, Bergland G, Bingham S, Brustad M, Bueno-de-Mesquita HB, Burdette L, Buring J, Calle EE, Chanock SJ, Clavel-Chapelon F, Cox DG, Dossus L, Feigelson HS, et al. Vitamin D receptor polymorphisms and breast cancer risk: results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium. Cancer Epidemiol. Biomarkers Prev. 18: 297-305 (2009). *

• McLean L, Patel T. Racial and ethnic variations in the epidemiology of intrahepatic cholangiocarcinoma in the United States. Liver Int. 26: 1047-1053 (2006). *

• McLennan PL, Abeywardena MY. Membrane basis for fish oil effects on the heart: linking natural hibernators to prevention of human sudden cardiac death. J. Membr. Biol. 206: 85-102 (2005). *

• McQueen MB, Murphy A, Kraft P, Su J, Lazarus R, Laird NM, Lange C, Van Steen K. Comparison of linkage and association strategies for quantitative traits using the COGA dataset. BMC Genet. 6 Suppl. 1: S96 (2005). *

• McWilliams R, Highsmith WE, Rabe KG, de Andrade M, Tordsen LA, Holtegaard LM, Petersen GM. Cystic fibrosis transmembrane regulator gene carrier status is a risk factor for young onset pancreatic adenocarcinoma. Gut 54: 1661-1662 (2005). *

• Mehta SH, Lau B, Afdhal NH, Thomas DL. Exceeding the limits of liver histology markers. J. Hepatol. 50: 36-41 (2009). *

• Meigs JB, Shrader P, Sullivan LM, McAteer JB, Fox CS, Dupuis J, Manning AK, Florez JC, Wilson PW, D'Agostino RB Sr, Cupples LA. Genotype score in addition to common risk factors for prediction of type 2 diabetes. N. Engl. J. Med. 359: 2208-2219 (2008). *

• Meinzer U, Idestrom M, Alberti C, Peuchmaur M, Belarbi N, Bellaiche M, Mougenot JF, Cezard JP, Finkel Y, Hugot JP. Ileal involvement is age dependent in pediatric Crohn's disease. Inflamm. Bowel Dis. 11: 639-644 (2005). *

• Meisinger C, Prokisch H, Gieger C, Soranzo N, Mehta D, Rosskopf D, Lichtner P, Klopp N, Stephens J, Watkins NA, Deloukas P, Greinacher A, Koenig W, Nauck M, Rimmbach C, Volzke H, Peters A, Illig T, Ouwehand WH, Meitinger T, Wichmann HE, Doring A. A genome-wide association study identifies three loci associated with mean platelet volume. Am. J. Hum. Genet. 84: 66-71 (2009). *

• Mellemkjaer L, Johansen C, Gridley G, Linet MS, Kjaer SK, Olsen JH. Crohn's disease and cancer risk (Denmark). Cancer Causes Control 11: 145-150 (2000). *

• Mellmann A, Bielaszewska M, Karch H. Intrahost genome alterations in enterohemorrhagic Escherichia coli. Gastroenterology 136: 1925-1938 (2009). *

• Melzer D, Perry JR, Hernandez D, Corsi AM, Stevens K, Rafferty I, Lauretani F, Murray A, Gibbs JR, Paolisso G, Rafiq S, Simon-Sanchez J, Lango H, Scholz S, Weedon MN, Arepalli S, Rice N, Washecka N, Hurst A, Britton A, et al. A genome-wide association study identifies protein quantitative trait loci (pQTLs). PLoS Genet. 4: e1000072 (2008). *

• Mendez-Sanchez N, Almeda-Valdes P, Uribe M. Alcoholic liver disease. An update. Ann. Hepatol. 4: 32-42 (2005).

• Mendez-Sanchez N, Chavez-Tapia NC, Uribe M. An update on non-alcoholic fatty liver disease. Rev. Invest. Clin. 56: 72-82 (2004).

• Mendez-Sanchez N, King-Martínez AC, Ramos MH, Pichardo-Bahena R, Uribe M. The Amerindian's genes in the Mexican population are associated with development of gallstone disease. Am. J. Gastroenterol. 99: 2166-2170 (2004). *

• Mendez-Sanchez N, Villa AR, Chavez-Tapia NC, Ponciano-Rodriguez G, Almeda-Valdes P, Gonzalez D, Uribe M. Trends in liver disease prevalence in Mexico from 2005 to 2050 through mortality data. Ann. Hepatol. 4: 52-55 (2005).

• Mendez-Sanchez N, Zamora-Valdes D, Vasquez-Fernandez F, Uribe M. Hepatocellular carcinoma in Hispanics. Ann. Hepatol. 6: 279-280 (2007). *

• Menon R, Velez DR, Simhan H, Ryckman K, Jiang L, Thorsen P, Vogel I, Jacobsson B, Merialdi M, Williams SM, Fortunato SJ. Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women. Am. J. Obstet. Gynecol. 194: 1616-1624 (2006). *

• Merchant AT, Curhan GC, Rimm EB, Willett WC, Fawzi WW. Intake of n-6 and n-3 fatty acids and fish and risk of community-acquired pneumonia in US men. Am. J. Clin. Nutr. 82: 668-674 (2005). *

• Merched AJ, Ko K, Gotlinger KH, Serhan CN, Chan L. Atherosclerosis: evidence for impairment of resolution of vascular inflammation governed by specific lipid mediators. FASEB J. 22: 3595-3606 (2008). *

• Meriggioli MN, Sanders DB. Autoimmune myasthenia gravis: emerging clinical and biological heterogeneity. Lancet Neurol. 8: 475-490 (2009).

• Merkesdal S, Kirchhoff T, Wolka D, Ladinek G, Kielhorn A, Rubbert-Roth A. Cost-effectiveness analysis of rituximab treatment in patients in Germany with rheumatoid arthritis after etanercept-failure. Eur. J. Health Econ. Dec 5 [Epub ahead of print] (2009).

• Merlino G, Valente M, Serafini A, Gigli GL. Restless legs syndrome: diagnosis, epidemiology, classification and consequences. Neurol. Sci. 28 Suppl. 1: S37-S46 (2007).

• Merriman NA, Putt ME, Metz DC, Yang YX. Hip fracture risk in patients with a diagnosis of pernicious anemia. Gastroenterology Dec 16 [Epub ahead of print] (2009). *

• Mesaros N, Nordmann P, Plesiat P, Roussel-Delvallez M, van Eldere J, Glupczynski Y, van Laethem Y, Jacobs F, Lebecque P, Malfroot A, Tulkens PM, van Bambeke F. Pseudomonas aeruginosa: resistance and therapeutic options at the turn of the new millennium. Clin. Microbiol. Infect. 13: 560-578 (2007). *

• Messias EL, Chen CY, Eaton WW. Epidemiology of schizophrenia: review of findings and myths. Psychiatr. Clin. North Am. 30: 323-338 (2007).

• Metcalf C. Crohn’s disease: an overview. Nurs. Stand. 16: 45-52 (2002). *

• Metcalf JV, Howel D, James OF, Bhopal R. Primary biliary cirrhosis: epidemiology helping the clinician. BMJ 312: 1181-1182 (1996). *

• Metzger MH, Heier M, Maki M, Bravi E, Schneider A, Lowel H, Illig T, Schuppan D, Wichmann HE. Mortality excess in individuals with elevated IgA anti-transglutaminase antibodies: the KORA/MONICA Augsburg Cohort Study 1989-1998. Eur. J. Epidemiol. 21: 359-365 (2006). *

• Meulenbelt I, Seymour AB, Nieuwland M, Huizinga TW, van Duijn CM, Slagboom PE. Association of the interleukin-1 gene cluster with radiographic signs of osteoarthritis of the hip. Arthritis Rheum. 50: 1179-1186 (2004). *

• Meyer A, Levy Y. Chapter 33: geoepidemiology of myasthenia gravis. Autoimmun. Rev. Nov 13 [Epub ahead of print] (2009).

• Mignone LI, Giovannucci E, Newcomb PA, Titus-Ernstoff L, Trentham-Dietz A, Hampton JM, Willett WC, Egan KM. Dietary carotenoids and the risk of invasive breast cancer. Int. J. Cancer 124: 2929-2937 (2009). *

• Mikaeloff Y, Caridade G, Assi S, Tardieu M, Suissa S. Hepatitis B vaccine and risk of relapse after a first childhood episode of CNS inflammatory demyelination. Brain 130: 1105-1110 (2007).

• Mikhak B, Hunter DJ, Spiegelman D, Platz EA, Hollis BW, Giovannucci E. Vitamin D receptor (VDR) gene polymorphisms and haplotypes, interactions with plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, and prostate cancer risk. Prostate 67: 911-923 (2007).

• Mikhak B, Hunter DJ, Spiegelman D, Platz EA, Wu K, Erdman JW Jr, Giovannucci E. Manganese superoxide dismutase (MnSOD) gene polymorphism, interactions with carotenoid levels, and prostate cancer risk. Carcinogenesis 29: 2335-2340 (2008). *

• Miller KL, Kelsey KT, Wiencke JK, Moghadassi M, Miike R, Liu M, Wrensch M. The C3435T polymorphism of MDR1 and susceptibility to adult glioma. Neuroepidemiology 25: 85-90 (2005).

• Miller MB, Lind GR, Li N, Jang SY. Genetic Analysis Workshop 15: simulation of a complex genetic model for rheumatoid arthritis in nuclear families including a dense SNP map with linkage disequilibrium between marker loci and trait loci. BMC Proc. 1 Suppl. 1: S4 (2007). *

• Milo R, Kahana E. Multiple sclerosis: geoepidemiology, genetics and the environment. Autoimmun. Rev. Nov 19 [Epub ahead of print] (2009).

• Min JY, Min KB, Sung J, Il Cho S. Linkage and association studies of joint morbidity from rheumatoid arthritis. J. Rheumatol. Dec 23 [Epub ahead of print] (2009).

• Minden K, Mingels A, Niewerth M, Heiligenhaus A, Ganser G. Juvenile idiopathic arthritis and uveitis: epidemiology including data from a national database. Klin. Monatsbl. Augenheilkd. 224: 469-472 (2007).

• Minelli C, Granell R, Newson R, Rose-Zerilli MJ, Torrent M, Ring SM, Holloway JW, Shaheen SO, Henderson JA. Glutathione-S-transferase genes and asthma phenotypes: a human genome epidemiology (HuGE) systematic review and meta-analysis including unpublished data. Int. J. Epidemiol. Dec 23 [Epub ahead of print] (2009).

• Minelli C, Thompson JR, Abrams KR, Lambert PC. Bayesian implementation of a genetic model-free approach to the meta-analysis of genetic association studies. Stat. Med. 24: 3845-3861 (2005). *

• Mishra PJ, Bertino JR. MicroRNA polymorphisms: the future of pharmacogenomics, molecular epidemiology and individualized medicine. Pharmacogenomics 10: 399-416 (2009).

• Mitra N, Ye TZ, Smith A, Chuai S, Kirchhoff T, Peterlongo P, Nafa K, Phillips MS, Offit K, Ellis NA. Localization of cancer susceptibility genes by genome-wide single-nucleotide polymorphism linkage-disequilibrium mapping. Cancer Res. 64: 8116-8125 (2004). *

• Miyagawa-Hayashino A, Haga H, Egawa H, Hayashino Y, Sakurai T, Minamiguchi S, Tanaka K, Manabe T. Outcome and risk factors of de novo autoimmune hepatitis in living-donor liver transplantation. Transplantation 78: 128-135 (2004).

• Mobley JL. Is rheumatoid arthritis a consequence of natural selection for enhanced tuberculosis resistance? Med. Hypotheses 62: 839-843 (2004).

• Mobley JL. Using epidemiology and archaeology to unearth new drug targets for rheumatoid arthritis therapy. Drug Discov. Today 11: 4-7 (2006).

• Mobley L, Kuo TM, Urato M, Boos J, Lozano-Gracia N, Anselin L. Predictors of endoscopic colorectal cancer screening over time in 11 states. Cancer Causes Control Nov 28 [Epub ahead of print] (2009). *

• Mockenhaupt M, Schopf E. Epidemiology of drug-induced severe skin reactions. Semin. Cutan. Med. Surg. 15: 236-243 (1996).

• Modell SM, Lehmann MH. The long QT syndrome family of cardiac ion channelopathies: a HuGE review. Genet. Med. 8: 143-155 (2006).

• Mohammed I, Cherkas LF, Riley SA, Spector, TD, Trudgill NJ. Genetic influences in irritable bowel syndrome: a twin study. Am. J. Gastroenterol. 100: 1340-1344 (2005). *

• Mohan V, Sudha V, Radhika G, Radha V, Rema M, Deepa R. Gene-environment interactions and the diabetes epidemic in India. Forum Nutr. 60: 118-126 (2007).

• Molineros JE, Kim-Howard X, Deshmukh H, Jacob CO, Harley JB, Nath SK. Admixture in Hispanic Americans: its impact on ITGAM association and implications for admixture mapping in SLE. Genes Immun. 10: 539-545 (2009).

• Mollazadegan K, Ludvigsson JF. Coeliac disease does not affect visual acuity: a study of young men in the Swedish national conscripts register. Scand. J. Gastroenterol. 44: 1304-1309 (2009).

• Mollazadegan K, Ludvigsson JF. Coeliac disease does not affect visual acuity: a study of young men in the Swedish national conscripts register. Scand. J. Gastroenterol. Aug 25 [Epub ahead of print] (2009). *

• Molokhia M, McKeigue P. Systemic lupus erythematosus: genes versus environment in high risk populations. Lupus 15: 827-832 (2006).

• Monach PA, Merkel PA. Genetics of vasculitis. Curr. Opin. Rheumatol. Jan 4 [Epub ahead of print] (2010).

• Monsen U. Inflammatory bowel disease. An epidemiological and genetic study. Acta Chir. Scand. Suppl. 559: 1-42 (1990).

• Montgomery SM, Ekbom A. Epidemiology of inflammatory bowel disease. Curr. Opin. Gastroenterol. 18: 416-420 (2002).

• Moors M, Vudattu NK, Abel J, Kramer U, Rane L, Ulfig N, Ceccatelli S, Seyfert-Margolies V, Fritsche E, Maeurer MJ. Interleukin-7 (IL-7) and IL-7 splice variants affect differentiation of human neural progenitor cells. Genes Immun. Oct 22 [Epub ahead of print] (2009).

• Morak MJ, van der Gaast A, Incrocci L, van Dekken H, Hermans JJ, Jeekel J, Hop WC, Kazemier G, van Eijck CH. Adjuvant intra-arterial chemotherapy and radiotherapy versus surgery alone in resectable pancreatic and periampullary cancer: a prospective randomized controlled trial. Ann. Surg. 248: 1031-1041 (2008).

• Moreno Sanchez D, Cassinello Ogea C, Gonzalez Blanco P, Pulido Ortega F, Castellano Tortajada G. Epidemiology of primary biliary cirrhosis in southern Madrid. Med. Clin. (Barc.) 94: 564-569 (1990).

• Morgan AW, Barrett JH, Griffiths B, Subramanian D, Robinson JI, Keyte VH, Ali M, Jones EA, Old RW, Ponchel F, Boylston AW, Situnayake RD, Markham AF, Emery P, Isaacs JD. Analysis of Fcgamma receptor haplotypes in rheumatoid arthritis: FCGR3A remains a major susceptibility gene at this locus, with an additional contribution from FCGR3B. Arthritis Res. Ther. 8: R5 (2006). *

• Morley R, Carlin JB, Pasco JA, Wark JD, Ponsonby AL. Maternal 25-hydroxyvitamin D concentration and offspring birth size: effect modification by infant VDR genotype. Eur. J. Clin. Nutr. 63: 802-804 (2009). *

• Morris AP, Zeggini E, Lindgren CM. Identification of novel putative rheumatoid arthritis susceptibility genes via analysis of rare variants. BMC Proc. 3 Suppl. 7: S131 (2009). *

• Morris MC. The role of nutrition in Alzheimer's disease: epidemiological evidence. Eur. J. Neurol. 16 Suppl. 1: 1-7 (2009).

• Morton LM, Wang SS, Bergen AW, Chatterjee N, Kvale P, Welch R, Yeager M, Hayes RB, Chanock SJ, Caporaso NE. DRD2 genetic variation in relation to smoking and obesity in the prostate, lung, colorectal, and ovarian cancer screening trial. Pharmacogenet. Genomics 16: 901-910 (2006).

• Morton LM, Wang SS, Cozen W, Linet MS, Chatterjee N, Davis S, Severson RK, Colt JS, Vasef MA, Rothman N, Blair A, Bernstein L, Cross AJ, De Roos AJ, Engels EA, Hein DW, Hill DA, Kelemen LE, Lim U, Lynch CF, Schenk M, Wacholder S, Ward MH, Zahm SH, et al. Etiologic heterogeneity among non-Hodgkin lymphoma subtypes. Blood 112: 5150-5160 (2008). *

• Mosa A, Trumstedt C, Eriksson E, Soehnlein O, Heuts F, Janik K, Klos A, Dittrich-Breiholz O, Kracht M, Hidmark A, Wigzell H, Rottenberg ME. Non-hematopoietic cells control the outcome of infection with Listeria monocytogenes in a NOD1-dependent manner. Infect. Immun. 77: 2908-2918 (2009). *

• Moses PL, Moore BR, Ferrentino N, Bensen SP, Vecchio JA. Inflammatory bowel disease. 1. Origins, presentation, and course. Postgrad. Med. 103: 77-84 (1998).

• Mossong J, Hens N, Friederichs V, Davidkin I, Broman M, Litwinska B, Siennicka J, Trzcinska A, Damme PV, Beutels P, Vyse A, Shkedy Z, Aerts M, Massari M, Gabutti G. Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection. Epidemiol. Infect. 136: 1059-1068 (2008).

• Motiwala AS, Li L, Kapur V, Sreevatsan S. Current understanding of the genetic diversity of Mycobacterium avium subsp. paratuberculosis. Microbes Infect. 8: 1406-1418 (2006).

• Motiwala AS, Strother M, Amonsin A, Byrum B, Naser SA, Stabel JR, Shulaw WP, Bannantine JP, Kapur V, Sreevatsan S. Molecular epidemiology of Mycobacterium avium subsp. paratuberculosis: evidence for limited strain diversity, strain sharing, and identification of unique targets for diagnosis. J. Clin. Microbiol. 41: 2015-2026 (2003). *

• Moum B, Ekbom A. Epidemiology of inflammatory bowel disease - methodological considerations. Dig. Liver Dis. 34: 364-369 (2002).

• Moum B, Ekbom A, Vatn MH, Aadland E, Sauar J, Lygren I, Schulz T, Stray N, Fausa O. Clinical course during the 1st year after diagnosis in ulcerative colitis and Crohn's disease. Results of a large, prospective population-based study in southeastern Norway, 1990-93. Scand. J. Gastroenterol. 32: 1005-1012 (1997).

• Mourao AF, Caetano-Lopes J, Costa P, Canhao H, Santos MJ, Pinto P, Brito I, Nicola P, Cavaleiro J, Teles J, Jose AS, Gomes M, Branco J, da Costa JT, Pedro JG, de Queiroz MV, Fonseca JE. Tumor necrosis factor-alpha -308 genotypes influence inflammatory activity and TNF-alpha serum concentrations in children with juvenile idiopathic arthritis. J. Rheumatol. 36: 837-842 (2009).

• Mowry EM, Balcer LJ, Galetta SL. Multiple sclerosis and the ophthalmologist. Compr. Ophthalmol. Update 8: 39-49 (2007).

• Moya-Quiles MR, Glover G, Mondejar-Lopez P, Pastor-Vivero MD, Fernandez-Sanchez A, Sanchez-Solís M. CFTR H609R mutation in Ecuadorian patients with cystic fibrosis. J. Cyst. Fibros. 8: 280-281 (2009).

• Moyer MS. A collaborative effort to define the epidemiology of pediatric inflammatory bowel disease: what can we learn from children with early-onset disease? J. Pediatr. 146: 7-8 (2005).

• Mozaffarian D. Fish and n-3 fatty acids for the prevention of fatal coronary heart disease and sudden cardiac death. Am. J. Clin. Nutr. 87: 1991S-1996S (2008). *

• Mozaffarian D. Fish oil and prevention of atrial fibrillation. J. Am. Coll. Cardiol. 50: 1513-1514 (2007).

• Mozaffarian D. Trans fatty acids - effects on systemic inflammation and endothelial function. Atheroscler. Suppl. 7: 29-32 (2006).

• Mozaffarian D, Stein PK, Prineas RJ, Siscovick DS. Dietary fish and omega-3 fatty acid consumption and heart rate variability in US adults. Circulation 117: 1130-1137 (2008). *

• Mu LN, Cao W, Zhang ZF, Cai L, Jiang QW, You NC, Goldstein BY, Wei GR, Chen CW, Lu QY, Zhou XF, Ding BG, Chang J, Yu SZ. Methylenetetrahydrofolate reductase (MTHFR) C677T and A1298C polymorphisms and the risk of primary hepatocellular carcinoma (HCC) in a Chinese population. Cancer Causes Control 18: 665-675 (2007). *

• Mucci LA, Spiegelman D. Vitamin D and prostate cancer risk - a less sunny outlook? J. Natl. Cancer Inst. 100: 759-761 (2008). *

• Mueller NJ, Fishman JA. How should we evaluate organ donors with active or prior infections? J. Hepatol. 45: 507-613 (2006). *

• Muhsen K, Cohen D. Helicobacter pylori infection and iron stores: a systematic review and meta-analysis. Helicobacter 13: 323-340 (2008). *

• Mulder CJ, Cellier C. Coeliac disease: changing views. Best Pract. Res. Clin. Gastroenterol. 19: 313-321 (2005).

• Mullan RJ, Bergstralh EJ, Farmer SA, Jacobson DJ, Hebbring SJ, Cunningham JM, Thibodeau SN, Lieber MM, Jacobsen SJ, Roberts RO. Growth factor, cytokine, and vitamin D receptor polymorphisms and risk of benign prostatic hyperplasia in a community-based cohort of men. Urology 67: 300-305 (2006).

• Muller T, Barkun AN, Martel M. Non-variceal upper GI bleeding in patients already hospitalized for another condition. Am. J. Gastroenterol. 104: 330-339 (2009).

• Munk EM, Pedersen L, Floyd A, Norgard B, Rasmussen HH, Sorensen HT. Inflammatory bowel diseases, 5-aminosalicylic acid and sulfasalazine treatment and risk of acute pancreatitis: a population-based case-control study. Am. J. Gastroenterol. 99: 884-888 (2004). *

• Munkholm P, Loftus Jr EV, Reinacher-Schick A, Kornbluth A, Mittmann U, Esendal B. Prevention of colorectal cancer in inflammatory bowel disease: value of screening and 5-aminosalicylates. Digestion 73: 11-19 (2006). *

• Munoz SJ, Stravitz RT, Gabriel DA. Coagulopathy of acute liver failure. Clin. Liver Dis. 13: 95-107 (2009).

• Muntinghe FL, Verduijn M, Zuurman MW, Grootendorst DC, Carrero JJ, Qureshi AR, Luttropp K, Nordfors L, Lindholm B, Brandenburg V, Schalling M, Stenvinkel P, Boeschoten EW, Krediet RT, Navis G, Dekker FW. CCR5 deletion protects against inflammation-associated mortality in dialysis patients. J. Am. Soc. Nephrol. 20: 1641-1619 (2009).

• Murakami K, Miyake Y, Sasaki S, Tanaka K, Ohya Y, Hirota Y; Osaka Maternal and Child Health Study Group. Education, but not occupation or household income, is positively related to favorable dietary intake patterns in pregnant Japanese women: the Osaka Maternal and Child Health Study. Nutr. Res. 29: 164-172 (2009). *

• Murakami K, Mizoue T, Sasaki S, Ohta M, Sato M, Matsushita Y, Mishima N. Dietary intake of folate, other B vitamins, and omega-3 polyunsaturated fatty acids in relation to depressive symptoms in Japanese adults. Nutrition 24: 140-147 (2008).

• Murakami K, Sasaki S. Dietary intake and depressive symptoms: a systematic review of observational studies. Mol. Nutr. Food Res. Dec 8 [Epub ahead of print] (2009). *

• Murakami K, Sasaki S, Takahashi Y, Uenishi K, Yamasaki M, Hayabuchi H, Goda T, Oka J, Baba K, Ohki K, Muramatsu K, Sugiyama Y. Total n-3 polyunsaturated fatty acid intake is inversely associated with serum C-reactive protein in young Japanese women. Nutr. Res. 28: 309-314 (2008). *

• Murff HJ, Shu XO, Li H, Dai Q, Kallianpur A, Yang G, Cai H, Wen W, Gao YT, Zheng W. A prospective study of dietary polyunsaturated fatty acids and colorectal cancer risk in Chinese women. Cancer Epidemiol. Biomarkers Prev. 18: 2283-2291 (2009).

• Murphy G, Pfeiffer R, Camargo MC, Rabkin CS. Meta-analysis shows that prevalence of Epstein-Barr virus-positive gastric cancer differs based on sex and anatomic location. Gastroenterology 137: 824-833 (2009). *

• Murphy G, Thornton J, McManus R, Swan N, Ryan B, Hughes DJ, O'Morain CA, O'Sullivan M. Association of gastric disease with polymorphisms in the inflammatory-related genes IL-1B, IL-1RN, IL-10, TNF and TLR4. Eur. J. Gastroenterol. Hepatol. 21: 630-635 (2009).

• Musa S, Thomson S, Cowan M, Rahman T. Clostridium difficile infection and inflammatory bowel disease. Scand. J. Gastroenterol. 45: 261-272 (2010). *

• Mutter J, Naumann J, Schneider R, Walach H, Haley B. Mercury and autism: accelerating evidence? Neuro. Endocrinol. Lett. 26: 439-446 (2005).

• Myers RP, Shaheen AA, Fong A, Burak KW, Wan A, Swain MG, Hilsden RJ, Sutherland L, Quan H. Epidemiology and natural history of primary biliary cirrhosis in a Canadian health region: a population-based study. Hepatology 50: 1884-1892 (2009). *

• Myleus A, Ivarsson A, Webb C, Danielsson L, Hernell O, Hogberg L, Karlsson E, Lagerqvist C, Norstrom F, Rosen A, Sandstrom O, Stenhammar L, Stenlund H, Wall S, Carlsson A. Celiac disease revealed in 3% of Swedish 12-year-olds born during an epidemic. J. Pediatr. Gastroenterol. Nutr. 49: 170-176 (2009).

• Nagano Y, Elborn JS, Millar BC, Goldsmith CE, Rendall J, Moore JE. Development of a novel PCR assay for the identification of the black yeast, Exophiala (Wangiella) dermatitidis from adult patients with cystic fibrosis (CF). J. Cyst. Fibros. 7: 576-580 (2008).

• Nahmias AJ, Nahmias SB, Danielsson D. The possible role of transplacentally-acquired antibodies to infectious agents, with molecular mimicry to nervous system sialic acid epitopes, as causes of neuromental disorders: prevention and vaccine implications. Clin. Dev. Immunol. 13: 167-183 (2006). *

• Naldi L, Mercuri SR. Smoking and psoriasis: from epidemiology to pathomechanisms. J. Invest. Dermatol. 129: 2741-2743 (2009). *

• Naldi L, Svensson A, Zenoni D, Diepgen T, Elsner P, Grob JJ, Coenraads PJ, Bouwes Bavinck JN, Maccagni A, Linder D, Williams H; on behalf of the European Dermato-Epidemiology Network (EDEN). Comparators, study duration, outcome measures and sponsorship in therapeutic trials of psoriasis. Update of the EDEN Psoriasis Survey 2001-2006. Br. J. Dermatol. Sep 24 [Epub ahead of print] (2009). *

• Nan H, Niu T, Hunter DJ, Han J. Missense polymorphisms in matrix metalloproteinase genes and skin cancer risk. Cancer Epidemiol. Biomarkers Prev. 17: 3551-3557 (2008). *

• Narain S, Richards HB, Satoh M, Sarmiento M, Davidson R, Shuster J, Sobel E, Hahn P, Reeves WH. Diagnostic accuracy for lupus and other systemic autoimmune diseases in the community setting. Arch. Intern. Med. 164: 2435-2441 (2004). *

• Narkewicz MR, Dell Olio D, Karpen SJ, Murray KF, Schwarz K, Yazigi N, Zhang S, Belle SH, Squires RH; Pediatric Acute Liver Failure Study Group. Pattern of diagnostic evaluation for the causes of pediatric acute liver failure: an opportunity for quality improvement. J. Pediatr. 155: 801-806.e1 (2009).

• Nath SK, Han S, Kim-Howard X, Kelly JA, Viswanathan P, Gilkeson GS, Chen W, Zhu C, McEver RP, Kimberly RP, Alarcon-Riquelme ME, Vyse TJ, Li QZ, Wakeland EK, Merrill JT, James JA, Kaufman KM, Guthridge JM, Harley JB. A nonsynonymous functional variant in integrin-alpha(M) (encoded by ITGAM) is associated with systemic lupus erythematosus. Nat. Genet. 40: 152-154 (2008). *

• Nath SK, Kelly JA, Reid J, Lam T, Gray-McGuire C, Namjou B, Aston CE, Harley JB. SLEB3 in systemic lupus erythematosus (SLE) is strongly related to SLE families ascertained through neuropsychiatric manifestations. Hum. Genet. 111: 54-58 (2002). *

• Nath SK, Namjou B, Hutchings D, Garriott CP, Pongratz C, Guthridge J, James JJ. Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12-13 and evidence for genetic heterogeneity. Eur. J. Hum. Genet. 12: 668-672 (2004). *

• Nath SK, Namjou B, Kilpatrick J, Garriott CP, Bruner GR, Scofield RH, Harley JB. A candidate region on 11p13 for systemic lupus erythematosus: a linkage identified in African-American families. J. Investig. Dermatol. Symp. Proc. 9: 64-67 (2004). *

• Nath SK, Quintero-Del-Rio AI, Kilpatrick J, Feo L, Ballesteros M, Harley JB. Linkage at 12q24 with systemic lupus erythematosus (SLE) is established and confirmed in Hispanic and European American families. Am. J. Hum. Genet. 74: 73-82 (2004). *

• NCI-NHGRI Working Group on Replication in Association Studies, Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Abecasis G, Altshuler D, Bailey-Wilson JE, Brooks LD, Cardon LR, Daly M, Donnelly P, Fraumeni JF, et al. Replicating genotype-phenotype associations. Nature 447: 655-660 (2007). *

• Negaard A, Mulahasanovic A, Reisaeter LA, Aasekjaer K, Sandvik L, Klow NE. Crohn's disease evaluated with magnetic resonance enteroclysis: diagnostic performance of experienced and inexperienced readers before and after training. Acta Radiol. 49: 967-974 (2008).

• Neimann AL, Shin DB, Wang X, Margolis DJ, Troxel AB, Gelfand JM. Prevalence of cardiovascular risk factors in patients with psoriasis. J. Am. Acad. Dermatol. 55: 829-835 (2006).

• Nelson L, Gormley R, Riddle MS, Tribble DR, Porter CK. The epidemiology of Guillain-Barre Syndrome in U.S. military personnel: a case-control study. BMC Res. Notes 2: 171 (2009). *

• Nelson WG, De Marzo AM, DeWeese TL, Isaacs WB. The role of inflammation in the pathogenesis of prostate cancer. J. Urol. 172: S6-S11 (2004).

• Ness JM, Chabas D, Sadovnick AD, Pohl D, Banwell B, Weinstock-Guttman B. Clinical features of children and adolescents with multiple sclerosis. Neurology 68: S37-S45 (2007).

• Neuhausen SL, Steele L, Ryan S, Mousavi M, Pinto M, Osann KE, Flodman P, Zone JJ. Co-occurrence of celiac disease and other autoimmune diseases in celiacs and their first-degree relatives. J. Autoimmun. 31: 160-165 (2008).

• Neuhouser ML, Sorensen B, Hollis BW, Ambs A, Ulrich CM, McTiernan A, Bernstein L, Wayne S, Gilliland F, Baumgartner K, Baumgartner R, Ballard-Barbash R. Vitamin D insufficiency in a multiethnic cohort of breast cancer survivors. Am. J. Clin. Nutr. 88: 133-139 (2008). *

• Newman B, Silverberg MS, Gu X, Zhang Q, Lazaro A, Steinhart AH, Greenberg GR, Griffiths AM, McLeod RS, Cohen Z, Fernandez-Vina M, Amos CI, Siminovitch K. CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease. Am. J. Gastroenterol. 99: 306-315 (2004). *

• Newman WG, Zhang Q, Liu X, Amos CI, Siminovitch KA. Genetic variants in IL-23R and ATG16L1 independently predispose to increased susceptibility to Crohn's disease in a Canadian population. J. Clin. Gastroenterol. 43: 444-447 (2009).

• Newton-Bishop JA, Beswick S, Randerson-Moor J, Chang YM, Affleck P, Elliott F, Chan M, Leake S, Karpavicius B, Haynes S, Kukalizch K, Whitaker L, Jackson S, Gerry E, Nolan C, Bertram C, Marsden J, Elder DE, Barrett JH, Bishop DT. Serum 25-hydroxyvitamin D3 levels are associated with Breslow thickness at presentation and survival from melanoma. J. Clin. Oncol. 27: 5439-5444 (2009).

• Ng B, Specks U, Offord KP, Matteson EL. Epidemiology of Wegener granulomatosis since the introduction of ANCA testing in Olmsted county, MN, 1990-1999. J. Clin. Rheumatol. 9: 387-388 (2003).

• Ng DP, Placha G, Choo S, Chia KS, Warram JH, Krolewski AS. A disease haplotype for advanced nephropathy in type 2 diabetes at the ACE locus. Diabetes 55: 2660-2663 (2006). *

• Nguyen GC, Tuskey A, Dassopoulos T, Harris ML, Brant SR. Rising hospitalization rates for inflammatory bowel disease in the United States between 1998 and 2004. Inflamm. Bowel Dis. 13: 1529-1535 (2007). *

• Nguyen GT, Carrington M, Beeler JA, Dean M, Aledort LM, Blatt PM, Cohen AR, DiMichele D, Eyster ME, Kessler CM, Konkle B, Leissinger C, Luban N, O'Brien SJ, Goedert JJ, O'Brien TR. Phenotypic expressions of CCR5-delta32/delta32 homozygosity. J. Acquir. Immune Defic. Syndr. 22: 75-82 (1999).

• Nicodemus KK, Liu W, Chase GA, Tsai YY, Fallin MD. Comparison of type I error for multiple test corrections in large single-nucleotide polymorphism studies using principal components versus haplotype blocking algorithms. BMC Genet. 6 Suppl. 1: S78 (2005). *

• Niechzial M, Grobe T, Dorning H, Raspe H, Nagel E. Changes in the quality of life after organ transplantations. Soz. Praventivmed. 44: 171-183 (1999).

• Nielsen NM, Frisch M, Rostgaard K, Wohlfahrt J, Hjalgrim H, Koch-Henriksen N, Melbye M, Westergaard T. Autoimmune diseases in patients with multiple sclerosis and their first-degree relatives: a nationwide cohort study in Denmark. Mult. Scler. 14: 823-829 (2008). *

• Nielsen NM, Westergaard T, Frisch M, Rostgaard K, Wohlfahrt J, Koch-Henriksen N, Melbye M, Hjalgrim H. Type 1 diabetes and multiple sclerosis: a Danish population-based cohort study. Arch. Neurol. 63: 1001-1004 (2006). *

• Nielsen OH, Rogler G, Hahnloser D, Thomsen OO. Diagnosis and management of fistulizing Crohn's disease. Nat. Clin. Pract. Gastroenterol. Hepatol. 6: 92-106 (2009).

• Nielsen OH, Vainer B, Rask-Madsen J. Non-IBD and noninfectious colitis. Nat. Clin. Pract. Gastroenterol. Hepatol. 5: 28-39 (2008). *

• Nielsen RG, Husby S. Eosinophilic oesophagitis: epidemiology, clinical aspects, and association to allergy. J. Pediatr. Gastroenterol. Nutr. 45: 281-289 (2007). *

• Nielsen T, Rostgaard K, Askling J, Steffensen R, Oturai A, Jersild C, Koch-Henriksen N, Sorensen P, Hjalgrim H. Effects of infectious mononucleosis and HLA-DRB1*15 in multiple sclerosis. Mult. Scler. 15: 431-436 (2009). *

• Nielsen TR, Pedersen M, Rostgaard K, Frisch M, Hjalgrim H. Correlations between Epstein-Barr virus antibody levels and risk factors for multiple sclerosis in healthy individuals. Mult. Scler. 13: 420-423 (2007). *

• Nielsen TR, Rostgaard K, Nielsen NM, Koch-Henriksen N, Haahr S, Sorensen PS, Hjalgrim H. Multiple sclerosis after infectious mononucleosis. Arch. Neurol. 64: 72-75 (2007). *

• Nieters A, Beckmann L, Deeg E, Becker N. Gene polymorphisms in Toll-like receptors, interleukin-10, and interleukin-10 receptor alpha and lymphoma risk. Genes Immun. 7: 615-624 (2006). *

• Nightingale AL, Farmer RD, de Vries CS. Incidence of clinically diagnosed systemic lupus erythematosus 1992-1998 using the UK General Practice Research Database. Pharmacoepidemiol. Drug Saf. 15: 656-661 (2006).

• Nightingale AL, Farmer RD, de Vries CS. Systemic lupus erythematosus prevalence in the U.K.: methodological issues when using the General Practice Research Database to estimate frequency of chronic relapsing-remitting disease. Pharmacoepidemiol. Drug Saf. 16: 144-151 (2007).

• Nijhawan PK, Therneau TM, Dickson ER, Boynton J, Lindor KD. Incidence of cancer in primary biliary cirrhosis: the Mayo experience. Hepatology 29: 1396-1398 (1999). *

• Nikolaus S, Schreiber S. Diagnostics of inflammatory bowel disease. Gastroenterology 133: 1670-1689 (2007). *

• Nikolov NP, Smith JA, Patronas NJ, Illei GG. Diagnosis and treatment of vasculitis of the central nervous system in a patient with systemic lupus erythematosus. Nat. Clin. Pract. Rheumatol. 2: 627-633 (2006). *

• Ning B, Nowell S, Sweeney C, Ambrosone CB, Williams S, Miao X, Liang G, Lin D, Stone A, Luke Ratnasinghe D, Manjanatha M, Lang NP, Kadlubar FF. Common genetic polymorphisms in the 5'-flanking region of the SULT1A1 gene: haplotypes and their association with platelet enzymatic activity. Pharmacogenet. Genomics 15: 465-473 (2005).

• Nistico L, Fagnani C, Coto I, Percopo S, Cotichini R, Limongelli MG, Paparo F, D'Alfonso S, Giordano M, Sferlazzas C, Magazzu G, Momigliano-Richiardi P, Greco L, Stazi MA. Concordance, disease progression, and heritability of coeliac disease in Italian twins. Gut 55: 803-808 (2006). *

• Nittke T, Kallay E, Manhardt T, Cross HS. Parallel elevation of colonic 1,25-dihydroxyvitamin D3 levels and apoptosis in female mice on a calcium-deficient diet. Anticancer Res. 29: 3727-3732 (2009).

• Nitz I, Fisher E, Grallert H, Li Y, Gieger C, Rubin D, Boeing H, Spranger J, Lindner I, Schreiber S, Rathmann W, Gohlke H, Doring A, Wichmann HE, Schrezenmeir J, Doring F, Illig T. Association of prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism with type 2 diabetes in two German study populations. J. Clin. Endocrinol. Metab. 92: 3183-3188 (2007). *

• Niu MT, Davis DM, Ellenberg S. Recombinant hepatitis B vaccination of neonates and infants: emerging safety data from the Vaccine Adverse Event Reporting System. Pediatr. Infect. Dis. J. 15: 771-776 (1996).

• Niu MT, Rhodes P, Salive M, Lively T, Davis DM, Black S, Shinefield H, Chen RT, Ellenberg SS. Comparative safety of two recombinant hepatitis B vaccines in children: data from the Vaccine Adverse Event Reporting System (VAERS) and Vaccine Safety Datalink (VSD). J. Clin. Epidemiol. 51: 503-510 (1998).

• Niu MT, Salive ME, Ellenberg SS. Neonatal deaths after hepatitis B vaccine: the vaccine adverse event reporting system, 1991-1998. Arch. Pediatr. Adolesc. Med. 153: 1279-1282 (1999).

• Niv Y, Abuksis G, Fraser GM. Epidemiology of ulcerative colitis in Israel: a survey of Israeli kibbutz settlements. Am. J. Gastroenterol. 95: 693-698 (2000). *

• Njajou OT, Alizadeh BZ, van Duijn CM. Is genetic screening for hemochromatosis worthwhile? Eur. J. Epidemiol. 19: 101-108 (2004).

• No authors listed. NIH state-of-the-science statement on endoscopic retrograde cholangiopancreatography (ERCP) for diagnosis and therapy. NIH Consens. State. Sci. Statements 19: 1-26 (2002). *

• Nokleby H, Feiring B. The Norwegian vaccination program. Tidsskr. Nor. Laegeforen. 126: 2538-2540 (2006).

• Norgaard M, Ratanajamit C, Jacobsen J, Skriver MV, Pedersen L, Sorensen HT. Metronidazole and risk of acute pancreatitis: a population-based case-control study. Aliment. Pharmacol. Ther. 21: 415-420 (2005). *

• Norgard B, Fonager K, Sorensen HT, Olsen J. Birth outcomes of women with ulcerative colitis: a nationwide Danish cohort study. Am. J. Gastroenterol. 95: 3165-3170 (2000). *

• Norgard B, Hundborg HH, Jacobsen BA, Nielsen GL, Fonager K. Disease activity in pregnant women with Crohn's disease and birth outcomes: a regional Danish cohort study. Am. J. Gastroenterol. 102: 1947-1954 (2007). *

• Norgard B, Pedersen L, Christensen LA, Sorensen HT. Therapeutic drug use in women with Crohn's disease and birth outcomes: a Danish nationwide cohort study. Am. J. Gastroenterol. 102: 1406-1413 (2007). *

• Norgard B, Pedersen L, Johnsen SP, Tarone RE, McLaughlin JK, Friis S, Sorensen HT. COX-2-selective inhibitors and the risk of upper gastrointestinal bleeding in high-risk patients with previous gastrointestinal diseases: a population-based case-control study. Aliment. Pharmacol. Ther. 19: 817-825 (2004). *

• Novak AJ, Slager SL, Fredericksen ZS, Wang AH, Manske MM, Ziesmer S, Liebow M, Macon WR, Dillon SR, Witzig TE, Cerhan JR, Ansell SM. Genetic variation in B-cell-activating factor is associated with an increased risk of developing B-cell non-Hodgkin lymphoma. Cancer Res. 69: 4217-4224 (2009). *

• Novak N, Yu CF, Bussmann C, Maintz L, Peng WM, Hart J, Hagemann T, Diaz-Lacava A, Baurecht HJ, Klopp N, Wagenpfeil S, Behrendt H, Bieber T, Ring J, Illig T, Weidinger S. Putative association of a TLR9 promoter polymorphism with atopic eczema. Allergy 62: 766-772 (2007).

• Nunez C, Barreiro M, Dominguez-Munoz JE, Lorenzo A, Zapata C, Pena AS. CARD15 mutations in patients with Crohn's disease in a homogeneous Spanish population. Am. J. Gastroenterol. 99: 450-456 (2004). *

• Nystrom M, Mutanen M. Diet and epigenetics in colon cancer. World J. Gastroenterol. 15: 257-263 (2009). *

• O'Brien TR. Interferon-alfa, interferon-lambda and hepatitis C. Nat. Genet. 41: 1048-1050 (2009). *

• O'Mara TA, Clements JA, Spurdle AB. The use of predictive or prognostic genetic biomarkers in endometrial and other hormone-related cancers: justification for extensive candidate gene single nucleotide polymorphism studies of the matrix metalloproteinase family and their inhibitors. Cancer Epidemiol. Biomarkers Prev. 18: 2352-2365 (2009). *

• O'Reilly PF, Coin LJ, Hoggart CJ. invertFREGENE: Software for simulating inversions in population genetic data. Bioinformatics Jan 26 [Epub ahead of print] (2010). *

• Ogino S, Nosho K, Baba Y, Kure S, Shima K, Irahara N, Toyoda S, Chen L, Kirkner GJ, Wolpin BM, Chan AT, Giovannucci EL, Fuchs CS. A cohort study of STMN1 expression in colorectal cancer: body mass index and prognosis. Am. J. Gastroenterol. 104: 2047-2056 (2009).

• Ogino S, Shima K, Baba Y, Nosho K, Irahara N, Kure S, Chen L, Toyoda S, Kirkner GJ, Wang YL, Giovannucci EL, Fuchs CS. Colorectal cancer expression of peroxisome proliferator-activated receptor-gamma (PPARG, PPARgamma) is associated with good prognosis. Gastroenterology 136: 1242-1250 (2009). *

• Oh DY, Baumann K, Hamouda O, Eckert JK, Neumann K, Kucherer C, Bartmeyer B, Poggensee G, Oh N, Pruss A, Jessen H, Schumann RR. A frequent functional Toll-like receptor 7 polymorphism is associated with accelerated HIV-1 disease progression. AIDS 23: 297-307 (2009).

• Oh SS, Chang SC, Cai L, Cordon-Cardo C, Ding BG, Greenland S, He N, Jiang Q, Kheifets L, Le A, Lee YC, Liu S, Lu ML, Mao JT, Morgenstern H, Mu1 LN, Pantuck A, Papp JC, Park SL, Rao JY, Reuter VE, Tashkin DP, Wang H, You NC, Yu SZ, Zhao JK, et al. Single nucleotide polymorphisms of eight inflammation-related genes and their associations with smoking-related cancers. Int. J. Cancer Jan 28 [Epub ahead of print] (2010). *

• Okazaki T, Wang MH, Rawsthorne P, Sargent M, Datta LW, Shugart YY, Bernstein CN, Brant SR. Contributions of IBD5, IL23R, ATG16L1, and NOD2 to Crohn's disease risk in a population-based case-control study: evidence of gene-gene interactions. Inflamm. Bowel Dis. 14: 1528-1541 (2008). *

• Olafsson S, Gudjonsson H, Selmi C, Amano K, Invernizzi P, Podda M, Gershwin ME. Antimitochondrial antibodies and reactivity to N. aromaticivorans proteins in Icelandic patients with primary biliary cirrhosis and their relatives. Am. J. Gastroenterol. 99: 2143-2146 (2004). *

• Oliva-Hemker M, Fiocchi C. Etiopathogenesis of inflammatory bowel disease: the importance of the pediatric perspective. Inflamm. Bowel Dis. 8: 112-128 (2002). *

• Oliveira AL, de Souza M, Carvalho-Dias VM, Ruiz MA, Silla L, Tanaka PY, Simoes BP, Trabasso P, Seber A, Lotfi CJ, Zanichelli MA, Araujo VR, Godoy C, Maiolino A, Urakawa P, Cunha CA, de Souza CA, Pasquini R, Nucci M. Epidemiology of bacteremia and factors associated with multi-drug-resistant Gram-negative bacteremia in hematopoietic stem cell transplant recipients. Bone Marrow Transplant. 39: 775-781 (2007).

• Oliver JE, Silman AJ. What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases. Arthritis Res. Ther. 11: 223 (2009). *

• Oliver JE, Worthington J, Silman AJ. Genetic epidemiology of rheumatoid arthritis. Curr. Opin. Rheumatol. 18: 141-146 (2006).

• Ollier W, Thomson W. Population genetics of rheumatoid arthritis. Rheum. Dis. Clin. North Am. 18: 741-759 (1992).

• Ollier WE, Harrison B, Symmons D. What is the natural history of rheumatoid arthritis? Best Pract. Res. Clin. Rheumatol. 15: 27-48 (2001).

• Ollier WE, MacGregor A. Genetic epidemiology of rheumatoid disease. Br. Med. Bull. 51: 267-285 (1995).

• Olmos M, Antelo M, Vazquez H, Smecuol E, Maurino E, Bai JC. Systematic review and meta-analysis of observational studies on the prevalence of fractures in coeliac disease. Dig. Liver Dis. 40: 46-53 (2008).

• Olnes MJ, Erlich R. A review and update on cholangiocarcinoma. Oncology 66: 167-179 (2004).

• Olofsson PS, Soderstrom LA, Jern C, Sirsjo A, Ria M, Sundler E, de Faire U, Wiklund PG, Ohrvik J, Hedin U, Paulsson-Berne G, Hamsten A, Eriksson P, Hansson GK. Genetic variants of TNFSF4 and risk for carotid artery disease and stroke. J. Mol. Med. 87: 337-346 (2009). *

• Olsen SF, Osterdal ML, Salvig JD, Mortensen LM, Rytter D, Secher NJ, Henriksen TB. Fish oil intake compared with olive oil intake in late pregnancy and asthma in the offspring: 16 y of registry-based follow-up from a randomized controlled trial. Am. J. Clin. Nutr. 88: 167-175 (2008). *

• Olsen SF, Osterdal ML, Salvig JD, Weber T, Tabor A, Secher NJ. Duration of pregnancy in relation to fish oil supplementation and habitual fish intake: a randomised clinical trial with fish oil. Eur. J. Clin. Nutr. 61: 976-985 (2007). *

• Olsson C, Hornell A, Ivarsson A, Sydner YM. The everyday life of adolescent coeliacs: issues of importance for compliance with the gluten-free diet. J. Hum. Nutr. Diet. 21: 359-367 (2008). *

• Ong JP, Younossi ZM. Epidemiology and natural history of NAFLD and NASH. Clin. Liver Dis.11: 1-16 (2007).

• Ong JP, Younossi ZM. Approach to the diagnosis and treatment of nonalcoholic fatty liver disease. Clin. Liver Dis. 9: 617-634 (2005).

• Oo YH, Gunson BK, Lancashire RJ, Cheng KK, Neuberger JM. Incidence of cancers following orthotopic liver transplantation in a single center: comparison with national cancer incidence rates for England and Wales. Transplantation 80: 759-764 (2005).

• Opilla M. Epidemiology of bloodstream infection associated with parenteral nutrition. Am. J. Infect. Control 36: S173.e5-e8 (2008). *

• Orel R, Kamhi T, Vidmar G, Mamula P. Epidemiology of pediatric chronic inflammatory bowel disease in Central and Western Slovenia, 1994-2005. J. Pediatr. Gastroenterol. Nutr. 48: 579-586 (2009).

• Orholm M, Munkholm P, Langholz E, Nielsen OH, Sorensen IA, Binder V. Familial occurrence of inflammatory bowel disease. N. Engl. J. Med. 324: 84-88 (1991).

• Origasa H, Yokoyama M, Matsuzaki M, Saito Y, Matsuzawa Y; The JELIS Investigators. Clinical importance of adherence to treatment with eicosapentaenoic acid by patients with hypercholesterolemia. Circ. J. Feb 9 [Epub ahead of print] (2010). *

• Ormerod AS, Cook MC. Epidemiology of primary systemic vasculitis in the Australian Capital Territory and south-eastern New South Wales. Intern. Med. J. 38: 816-823 (2008). *

• Osorio J. Human bacterium induces colon tumors in mice through activation of Th17 cells. Nat. Rev. Gastroenterol. Hepatol. 6: 688 (2009). *

• Osterman MT, Kundu R, Lichtenstein GR, Lewis JD. Association of 6-thioguanine nucleotide levels and inflammatory bowel disease activity: a meta-analysis. Gastroenterology 130: 1047-1053 (2006). *

• Ott SJ, Musfeldt M, Wenderoth DF, Hampe J, Brant O, Folsch UR, Timmis KN, Schreiber S. Reduction in diversity of the colonic mucosa associated bacterial microflora in patients with active inflammatory bowel disease. Gut 53: 685-693 (2004). *

• Ouchi K, Suzuki Y, Shirakawa T, Kishi F. Polymorphism of SLC11A1 (formerly NRAMP1) gene confers susceptibility to Kawasaki disease. J. Infect. Dis. 187: 326-329 (2003). *

• Owens RC. Clostridium difficile-associated disease: changing epidemiology and implications for management. Drugs 67: 487-502 (2007).

• Palmer LJ, Burton PR, James AL, Musk AW, Cookson WO. Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families. Eur. J. Hum. Genet. 8: 853-860 (2000). *

• Palmer LJ, Cookson WO, James AL, Musk AW, Burton PR. Gibbs sampling-based segregation analysis of asthma-associated quantitative traits in a population-based sample of nuclear families. Genet. Epidemiol. 20: 356-372 (2001).

• Palomaki GE, FitzSimmons SC, Haddow JE. Clinical sensitivity of prenatal screening for cystic fibrosis via CFTR carrier testing in a United States panethnic population. Genet. Med. 6: 405-414 (2004).

• Pan F, Tang X, Zhang K, Li X, Xu J, Chen H, Ye D. Genetic susceptibility and haplotype analysis between Fcgamma receptor IIB and IIIA gene with systemic lupus erythematosus in Chinese population. Lupus 17: 733-738 (2008). *

• Pan F, Ye D, Zhang K, Li X, Xu J, Chen H. Gln50Ter polymorphism of Fcgamma receptor IIB gene associated with genetic susceptibility to human systemic lupus erythematosus in Chinese populations. Arch. Dermatol. Res. 299: 47-51 (2007). *

• Pan F, Zhang K, Li X, Xu J, Chen H, Wang Y, Ye D. Study on genetic susceptibility of the single nucleotide polymorphism of FCGR3A gene and systemic lupus erythematosus. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 24: 544-547 (2007).

• Pan F, Zhang K, Li X, Xu J, Hao J, Ye D. Association of Fcgamma receptor IIB gene polymorphism with genetic susceptibility to systemic lupus erythematosus in Chinese populations-A family-based association study. J. Dermatol. Sci. 43: 35-41 (2006).

• Pan HF, Wu GC, Li WP, Li XP, Ye DQ. High mobility group box 1: a potential therapeutic target for systemic lupus erythematosus. Mol. Biol. Rep. Feb 27 [Epub ahead of print] (2009). *

• Pan HF, Zhang N, Li WX, Tao JH, Ye DQ. TIM-3 as a new therapeutic target in systemic lupus erythematosus. Mol. Biol. Rep. Sep 19 [Epub ahead of print] (2009). *

• Pande M, Chen J, Amos CI, Lynch PM, Broaddus R, Frazier ML. Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a Caucasian Lynch syndrome population. Cancer Epidemiol. Biomarkers Prev. 16: 1753-1759 (2007). *

• Panoulas VF, Douglas KM, Smith JP, Stavropoulos-Kalinoglou A, Metsios GS, Nightingale P, Kitas GD. Transforming growth factor-beta1 869T/C, but not interleukin-6 -174G/C, polymorphism associates with hypertension in rheumatoid arthritis. Rheumatology (Oxford) 48: 113-118 (2009). *

• Papantoniou K, Fito M, Covas MI, Munoz D, Schroder H. trans Fatty acid consumption, lifestyle and type 2 diabetes prevalence in a Spanish population. Eur. J. Nutr. Feb 4 [Epub ahead of print] (2010). *

• Pardi DS, D'Haens G, Shen B, Campbell S, Gionchetti P. Clinical guidelines for the management of pouchitis. Inflamm. Bowel Dis. 15: 1424-1431 (2009).

• Pardi DS, Loftus EV Jn, Smyrk TC, Kammer P, Tremaine WJ, Schleck CD, Harmsen WS, Zinsmeister AR, Melton III LJ, Sandborn WJ. The epidemiology of microscopic colitis: a population-based study in Olmsted County, Minnesota. Gut 56: 504-508 (2007). *

• Pardi DS, Sandborn WJ. Systematic review: the management of pouchitis. Aliment. Pharmacol. Ther. 23: 1087-1096 (2006). *

• Pardi DS, Tremaine WJ, Sandborn WJ, Loftus EV Jr, Poland GA, Harmsen WS, Zinsmeister AR, Melton LJ 3rd. Early measles virus infection is associated with the development of inflammatory bowel disease. Am. J. Gastroenterol. 95: 1480-1485 (2000). *

• Parente F, Greco S, Molteni M, Cucino C, Maconi G, Sampietro GM, Danelli PG, Cristaldi M, Bianco R, Gallus S, Bianchi Porro G. Role of early ultrasound in detecting inflammatory intestinal disorders and identifying their anatomical location within the bowel. Aliment. Pharmacol. Ther. 18: 1009-1016 (2003). *

• Parikh-Patel A, Gold E, Mackay IR, Gershwin ME. The geoepidemiology of primary biliary cirrhosis: contrasts and comparisons with the spectrum of autoimmune diseases. Clin. Immunol. 91: 206-218 (1999). *

• Parikh-Patel A, Gold E, Utts J, Gershwin ME. The association between gravidity and primary biliary cirrhosis. Ann. Epidemiol. 12: 264-272 (2002). *

• Parikh-Patel A, Gold EB, Utts J, Worman H, Krivy KE, Gershwin ME. Functional status of patients with primary biliary cirrhosis. Am. J. Gastroenterol. 97: 2871-2879 (2002). *

• Parikh-Patel A, Gold EB, Worman H, Krivy KE, Gershwin ME. Risk factors for primary biliary cirrhosis in a cohort of patients from the United States. Hepatology 33: 16-21 (2001). *

• Park BL, Cheong HS, Kim LH, Choi YH, Namgoong S, Park HS, Hong SJ, Choi BW, Lee JH, Park CS, Shin HD. Association analysis of signal transducer and activator of transcription 4 (STAT4) polymorphisms with asthma. J. Hum. Genet. 50: 133-138 (2005). *

• Park BL, Kim LH, Choi YH, Cheong HS, Park HS, Hong SJ, Choi BW, Lee JH, Uh ST, Park CS, Shin HD. Association analysis of monocyte chemotactic protein-3 (MCP3) polymorphisms with asthmatic phenotypes. J. Biochem. Mol. Biol. 38: 77-81 (2005). *

• Park BL, Kim LH, Choi YH, Lee JH, Rhim T, Lee YM, Uh ST, Park HS, Choi BW, Hong SJ, Park CS, Shin HD. Interleukin 3 (IL3) polymorphisms associated with decreased risk of asthma and atopy. J. Hum. Genet. 49: 517-527 (2004). *

• Park BL, Kim LH, Shin HD, Park YW, Uhm WS, Bae SC. Association analyses of DNA methyltransferase-1 (DNMT1) polymorphisms with systemic lupus erythematosus. J. Hum. Genet. 49: 642-646 (2004). *

• Park JS, Cheong JY, Kang JK, Cho JH, Yu S, Shin HD, Park BL, Cho SW. Association of interleukin-12 gene polymorphism with persistence of hepatitis B virus infection and hepatocellular carcinoma. Korean J. Gastroenterol. 50: 313-318 (2007).

• Parks CG, Cooper GS. Occupational exposures and risk of systemic lupus erythematosus: a review of the evidence and exposure assessment methods in population- and clinic-based studies. Lupus 15: 728-736 (2006).

• Parks CG, Hudson LL, Cooper GS, Dooley MA, Treadwell EL, St Clair EW, Gilkeson GS, Pandey JP. CTLA-4 gene polymorphisms and systemic lupus erythematosus in a population-based study of whites and African-Americans in the southeastern United States. Lupus 13: 784-791 (2004).

• Patch C, Roderick P, Rosenberg W. Haemochromatosis: the need for an agreed case definition. J. Hepatol. 43: 911 (2005). *

• Patel M, Clarke AM, Bruce IN, Symmons DP. The prevalence and incidence of biopsy-proven lupus nephritis in the UK: evidence of an ethnic gradient. Arthritis Rheum. 54: 2963-2969 (2006). *

• Patel T, Singh P. Cholangiocarcinoma: emerging approaches to a challenging cancer. Curr. Opin. Gastroenterol. 23: 317-323 (2007).

• Paterson AD. Genetic epidemiology of type 1 diabetes. Curr. Diab. Rep. 6: 139-146 (2006).

• Patsopoulos NA, Ioannidis JP. Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis. Ann. Rheum. Dis. Apr 27 [Epub ahead of print] (2009).

• Patterson JM, Wall M, Berge J, Milla C. Gender differences in treatment adherence among youth with cystic fibrosis: development of a new questionnaire. J. Cyst. Fibros. 7: 154-164 (2008).

• Pattison DJ, Winyard PG. Dietary antioxidants in inflammatory arthritis: do they have any role in etiology or therapy? Nat. Clin. Pract. Rheumatol. 4: 590-596 (2008).

• Pattison EJ, Harrison BJ, Griffiths CE, Silman AJ, Bruce IN. Environmental risk factors for the development of psoriatic arthritis: results from a case control study. Ann. Rheum. Dis. 67: 672-676 (2008).

• Paul T, Birnbaum A, Pal DK, Pittman N, Ceballos C, Leleiko NS, Benkov K. Distinct phenotype of early childhood inflammatory bowel disease. J. Clin. Gastroenterol. 40: 583-586 (2006).

• Pavlovic-Calic N, Salkic NN, Gegic A, Smajic M, Alibegovic E. Crohn's disease in Tuzla region of Bosnia and Herzegovina: a 12-year study (1995-2006). Int. J. Colorectal Dis. 23: 957-964 (2008). *

• Pawitan Y, Seng KC, Magnusson PK.. How many genetic variants remain to be discovered? PLoS One 4: e7969 (2009). *

• Pedersen M, Jacobsen S, Garred P, Madsen HO, Klarlund M, Svejgaard A, Pedersen BV, Wohlfahrt J, Frisch M. Strong combined gene-environment effects in anti-cyclic citrullinated peptide-positive rheumatoid arthritis: a nationwide case-control study in Denmark. Arthritis Rheum. 56: 1446-1453 (2007). *

• Pekmezovic T, Drulovic J, Milenkovic M, Jarebinski M, Stojsavljevic N, Mesaros S, Kisic D, Kostic J. Lifestyle factors and multiple sclerosis: a case-control study in Belgrade. Neuroepidemiology 27: 212-216 (2006).

• Pena AS. Genetics of inflammatory bowel diseases - past, present, and future. Dig. Dis. 21: 85-90 (2003).

• Pender MP. Preventing and curing multiple sclerosis by controlling Epstein-Barr virus infection. Autoimmun. Rev. 8: 563-568 (2009).

• Penders J, Stobberingh EE, van den Brandt PA, Thijs C. The role of the intestinal microbiota in the development of atopic disorders. Allergy 62: 1223-1236 (2007). *

• Perez-Perez GI, Rothenbacher D, Brenner H. Epidemiology of Helicobacter pylori infection. Helicobacter 9 Suppl. 1: 1-6 (2004).

• Peritz AE, Gasparro FP. Psoriasis, PUVA, and skin cancer - molecular epidemiology: the curious question of T --> A transversions. J. Invest. Dermatol. Symp. Proc. 4: 11-16 (1999).

• Persson C, Engstrand L, Nyren O, Hansson LE, Enroth H, Ekstrom AM, Ye W. Interleukin 1-beta gene polymorphisms and risk of gastric cancer in Sweden. Scand. J. Gastroenterol. 44: 339-345 (2009). *

• Persson PG, Ahlbom A. Relative risk is a relevant measure of association of left-handedness with inflammatory bowel disease. Neuropsychologia 26: 737-740 (1988).

• Persson PG, Hellers G, Ahlbom A. Use of oral moist snuff and inflammatory bowel disease. Int. J. Epidemiol. 22: 1101-1103 (1993).

• Persson PG, Leijonmarck CE, Bernell O, Hellers G, Ahlbom A. Risk indicators for inflammatory bowel disease. Int. J. Epidemiol. 22: 268-272 (1993).

• Pesut D, Ciobanu L, Nagorni-Obradovic L. Pulmonary rehabilitation in chronic respiratory diseases - from goals to outcomes. Pneumologia 57: 65-69 (2008).

• Peter O. Lyme borreliosis: from the erythema migrans to Lyme arthritis. Rev. Med. Suisse. 2: 727-728, 730-731 (2006).

• Peters KM. Non-infective inflammations of the vertebral spine. Z. Orthop. Ihre. Grenzgeb. 145: R1-R24 (2007).

• Peters MJ, van Halm VP, Nurmohamed MT, Damoiseaux J, Tervaert JW, Twisk JW, Dijkmans BA, Voskuyl AE. Relations between autoantibodies against oxidized low-density lipoprotein, inflammation, subclinical atherosclerosis, and cardiovascular disease in rheumatoid arthritis. J. Rheumatol. 35: 1495-1499 (2008).

• Peters U, Hayes RB, Chatterjee N, Shao W, Schoen RE, Pinsky P, Hollis BW, McGlynn KA; Prostate, Lung, Colorectal and Ovarian Cancer Screening Project Team. Circulating vitamin D metabolites, polymorphism in vitamin D receptor, and colorectal adenoma risk. Cancer Epidemiol. Biomarkers Prev. 13: 546-552 (2004). *

• Peterson S, Bigler J, Horner NK, Potter JD, Lampe JW. Cruciferae interact with the UGT1A1*28 polymorphism to determine serum bilirubin levels in humans. J. Nutr. 135: 1051-1055 (2005). *

• Petiot V, Quantin C, Le Teuff G, Chavance M, Binquet C, Abrahamowicz M, Moreau T. Disability evolution in multiple sclerosis: how to deal with missing transition times in the Markov model? Neuroepidemiology 28: 56-64 (2007).

• Peyrin-Biroulet L, Standaert-Vitse A, Branche J, Chamaillard M. IBD serological panels: facts and perspectives. Inflamm. Bowel Dis. 13: 1561-1566 (2007). *

• Pezzolesi MG, Nam M, Nagase T, Klupa T, Dunn JS, Mlynarski WM, Rich SS, Warram JH, Krolewski AS. Examination of candidate chromosomal regions for type 2 diabetes reveals a susceptibility locus on human chromosome 8p23.1. Diabetes 53: 486-491 (2004). *

• Phillips E, Mallal S. Drug hypersensitivity in HIV. Curr. Opin. Allergy Clin. Immunol. 7: 324-330 (2007).

• Picardi A, Mazzotti E, Gaetano P, Cattaruzza MS, Baliva G, Melchi CF, Biondi M, Pasquini P. Stress, social support, emotional regulation, and exacerbation of diffuse plaque psoriasis. Psychosomatics 46: 556-564 (2005).

• Picchioni D, Hope CR, Harsh JR. A case-control study of the environmental risk factors for narcolepsy. Neuroepidemiology 29: 185-192 (2007).

• Picco MF, Cangemi JR. Inflammatory bowel disease in the elderly. Gastroenterol. Clin. North Am. 38: 447-462 (2009).

• Pierce KK, Kirkpatrick BD. Update on human infections caused by intestinal protozoa. Curr. Opin. Gastroenterol. 25: 12-17 (2009).

• Pierik M, Joossens S, Van Steen K, Van Schuerbeek N, Vlietinck R, Rutgeerts P, Vermeire S. Toll-like receptor-1, -2, and -6 polymorphisms influence disease extension in inflammatory bowel diseases. Inflamm. Bowel Dis. 12: 1-8 (2006). *

• Pierik M, Yang H, Barmada MM, Cavanaugh JA, Annese V, Brant SR, Cho JH, Duerr RH, Hugot JP, McGovern DP, Paavola-Sakki P, Radford-Smith GL, Pavli P, Silverberg MS, Schreiber S, Taylor KD, Vlietinck R; for the IBD International Genetics Consortium. The IBD International Genetics Consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction. Inflamm. Bowel Dis. 11: 1-7 (2005). *

• Pikus L, Woo JH, Wolf RL, Herskovits EH, Moonis G, Jawad AF, Krejza J, Melhem ER. Artificial multiple sclerosis lesions on simulated FLAIR brain MR images: echo time and observer performance in detection. Radiology 239: 238-245 (2006). *

• Pilz S, Tomaschitz A, Obermayer-Pietsch B, Dobnig H, Pieber TR. Epidemiology of vitamin D insufficiency and cancer mortality. Anticancer Res. 29: 3699-3704 (2009).

• Pla X, Vergara M, Gil M, Dalmau B, Cistero B, Bella RM, Real J. Incidence, prevalence and clinical course of primary biliary cirrhosis in a Spanish community. Eur. J. Gastroenterol. Hepatol. 19: 859-864 (2007).

• Plant D, Young HS, Watson RE, Worthington J, Griffiths CE. The CX3CL1-CX3CR1 system and psoriasis. Exp. Dermatol. 15: 900-903 (2006). *

• Platz EA, De Marzo AM. Epidemiology of inflammation and prostate cancer. J. Urol. 171: S36-S40 (2004).

• Platz EA, Hankinson SE, Hollis BW, Colditz GA, Hunter DJ, Speizer FE, Giovannucci E. Plasma 1,25-dihydroxy- and 25-hydroxyvitamin D and adenomatous polyps of the distal colorectum. Cancer Epidemiol. Biomarkers Prev. 9: 1059-1065 (2000). *

• Pless RP. Recent differing expert opinions regarding the safety profile of hepatitis B vaccines: is there really a controversy? Expert Opin. Drug Saf. 2: 451-455 (2003).

• Pletz MW, Sauer-Heilborn A, Kohnlein T, Seidler U, Lamprecht G. Cystic fibrosis in adults. Internist (Berl.) Feb 4 [Epub ahead of print] (2010).

• Plutzer J, Karanis P. Genetic polymorphism in Cryptosporidium species: an update. Vet. Parasitol. 165: 187-199 (2009). *

• Poegel K, Riedel H. Bile duct diseases and the liver. Epidemiology, pathogenesis, clinical aspects and prognosis of secondary cholangiogenic liver damage. Z. Arztl. Fortbild. (Jena) 81: 705-708 (1987).

• Ponsioen CY. Incidence and prevalence of PSC around the world. Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper’s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 61. October 15-16 (2003). *

• Ponsonby AL, McMichael A, van der Mei I. Ultraviolet radiation and autoimmune disease: insights from epidemiological research. Toxicology 181-182: 71-78 (2002). *

• Ponsonby AL, van der Mei I, Dwyer T, Blizzard L, Taylor B, Kemp A, Simmons R, Kilpatrick T. Exposure to infant siblings during early life and risk of multiple sclerosis. JAMA 293: 463-469 (2005). *

• Poo JL, Gongora J. Hepatic hematoma and hepatic rupture in pregnancy. Ann. Hepatol. 5: 224-226 (2006). *

• Poole EM, Hsu L, Xiao L, Kulmacz RJ, Carlson CS, Rabinovitch PS, Makar KW, Potter JD, Ulrich CM. Genetic variation in prostaglandin E2 synthesis and signaling, prostaglandin dehydrogenase, and the risk of colorectal adenoma. Cancer Epidemiol. Biomarkers Prev. Jan 19 [Epub ahead of print] (2010). *

• Popat RA, Tanner CM, Eeden SK, Bernstein AL, Bloch DA, Leimpeter A, McGuire V, Nelson LM. Effect of non-steroidal anti-inflammatory medications on the risk of amyotrophic lateral sclerosis. Amyotroph. Lateral Scler. 8: 157-163 (2007).

• Pope JE, Krizova A, Garg AX, Thiessen-Philbrook H, Ouimet JM. Campylobacter reactive arthritis: a systematic review. Semin. Arthritis Rheum. 37: 48-55 (2007). *

• Porojnicu AC, Robsahm TE, Dahlback A, Berg JP, Christiani D, Bruland OS, Moan J. Seasonal and geographical variations in lung cancer prognosis in Norway. Does vitamin D from the sun play a role? Lung Cancer 55: 263-270 (2007).

• Portincasa P, Vacca M, Moschetta A, Petruzzelli M, Palasciano G, van-Erpecum KJ, van-Berge-Henegouwen GP. Primary sclerosing cholangitis: updates in diagnosis and therapy. World J. Gastroenterol. 11: 7-16 (2005). *

• Portugal I, Barreiro L, Vultos T, Macedo R, Furtado C, Fonseca Antunes A, Brum L. Molecular epidemiology of Mycobacterium tuberculosis in Lisbon. Rev. Port. Pneumol. 14: 239-259 (2008).

• Poser CM, Brinar VV. The accuracy of prevalence rates of multiple sclerosis: a critical review. Neuroepidemiology 29: 150-155 (2007).

• Pott J, Basler T, Duerr CU, Rohde M, Goethe R, Hornef MW. Internalization-dependent recognition of Mycobacterium avium subsp. paratuberculosis by intestinal epithelial cells. Cell. Microbiol. 11: 1802-1815 (2009). *

• Poudel-Tandukar K, Nanri A, Matsushita Y, Sasaki S, Ohta M, Sato M, Mizoue T. Dietary intakes of alpha-linolenic and linoleic acids are inversely associated with serum C-reactive protein levels among Japanese men. Nutr. Res. 29: 363-370 (2009). *

• Poynter JN, Gruber SB, Higgins PD, Almog R, Bonner JD, Rennert HS, Low M, Greenson JK, Rennert G. Statins and the risk of colorectal cancer. N. Engl. J. Med. 352: 2184-2192 (2005). *

• Poynter JN, Jacobs ET, Figueiredo JC, Lee WH, Conti DV, Campbell PT, Levine AJ, Limburg P, Le Marchand L, Cotterchio M, Newcomb PA, Potter JD, Jenkins MA, Hopper JL, Duggan DJ, Baron JA, Haile RW. Genetic variation in the vitamin D receptor (VDR) and the vitamin D-binding protein (GC) and risk for colorectal cancer: results from the colon cancer family registry. Cancer Epidemiol. Biomarkers Prev. Jan 19 [Epub ahead of print] (2010). *

• Pratt DS. Cholestasis and cholestatic syndromes. Curr. Opin. Gastroenterol. 21: 270-274 (2005). *

• Prieto S, Grau JM. The geoepidemiology of autoimmune muscle disease. Autoimmun. Rev. Nov 8 [Epub ahead of print] (2009).

• Prince MI, James OF. The epidemiology of primary biliary cirrhosis. Clin. Liver Dis. 7: 795-819 (2003).

• Pruunsild C, Uibo K, Liivamagi H, Tarraste S, Talvik T, Pelkonen P. Incidence of juvenile idiopathic arthritis in children in Estonia: a prospective population-based study. Scand. J. Rheumatol. 36: 7-13 (2007). *

• Psaltopoulou T, Kyrozis A, Stathopoulos P, Trichopoulos D, Vassilopoulos D, Trichopoulou A. Diet, physical activity and cognitive impairment among elders: the EPIC-Greece cohort (European Prospective Investigation into Cancer and Nutrition). Public Health Nutr. 11: 1054-1062 (2008). *

• Pugliatti M, Rosati G, Carton H, Riise T, Drulovic J, Vecsei L, Milanov I. The epidemiology of multiple sclerosis in Europe. Eur. J. Neurol. 13: 700-722 (2006). *

• Purdue MP, Lan Q, Wang SS, Kricker A, Menashe I, Zheng TZ, Hartge P, Grulich AE, Zhang Y, Morton LM, Vajdic C, Holford TR, Severson RK, Leaderer B, Cerhan JR, Yeager M, Cozen W, Jacobs K, Davis S, Rothman N, Chanock SJ, Chatterjee N, Armstrong BK. A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma. Carcinogenesis 30: 275-281 (2009). *

• Pushpakom SP, Herrick AL, Kumar S, Worthington J. Polymorphisms in COL15 gene are not associated with systemic sclerosis. J. Rheumatol. 35: 251-253 (2008).

• Qi L, Zhang C, van Dam RM, Hu FB. Interleukin-6 genetic variability and adiposity: associations in two prospective cohorts and systematic review in 26,944 individuals. J. Clin. Endocrinol. Metab. 92: 3618-3625 (2007). *

• Qiao YL, Dawsey SM, Kamangar F, Fan JH, Abnet CC, Sun XD, Johnson LL, Gail MH, Dong ZW, Yu B, Mark SD, Taylor PR. Total and cancer mortality after supplementation with vitamins and minerals: follow-up of the Linxian General Population Nutrition Intervention Trial. J. Natl. Cancer Inst. 101: 507-518 (2009). *

• Qiu L, Wang Z, Shi X, Wang Z. Associations between XPC polymorphisms and risk of cancers: a meta-analysis. Eur. J. Cancer 44: 2241-2253 (2008). *

• Qu XH, Huang XL, Xiong P, Zhu CY, Huang YL, Lu LG, Sun X, Rong L, Zhong L, Sun DY, Lin H, Cai MC, Chen ZW, Hu B, Wu LM, Jiang YB, Yan WL. Does Helicobacter pylori infection play a role in iron deficiency anemia? A meta-analysis. World J. Gastroenterol. 16: 886-896 (2010). *

• Queiro R, Moreno P, Sarasqueta C, Alperi M, Riestra JL, Ballina J. Synovitis-acne-pustulosis-hyperostosis-osteitis syndrome and psoriatic arthritis exhibit a different immunogenetic profile. Clin. Exp. Rheumatol. 26: 125-128 (2008).

• Queiro R, Sarasqueta C, Torre JC, Tinture T, Lopez-Lagunas I. Prevalence and predictors of cervical involvement in psoriatic spondyloarthropathy. J. Clin. Rheumatol. 8: 23-29 (2002).

• Quinn MJ. Diabetes, diet and autonomic denervation. Med. Hypotheses Oct 20 [Epub ahead of print] (2009).

• Rabeneck L, Davila JA, El-Serag HB. Is there a true "shift" to the right colon in the incidence of colorectal cancer? Am. J. Gastroenterol. 98: 1400-1409 (2003). *

• Rabeneck L, El-Serag HB, Davila JA, Sandler RS. Outcomes of colorectal cancer in the United States: no change in survival (1986-1997). Am. J. Gastroenterol. 98: 471-477 (2003). *

• Raberg L, Sim D, Read AF. Disentangling genetic variation for resistance and tolerance to infectious diseases in animals. Science 318: 812-814 (2007). *

• Racine R, Grandcolas L, Grison S, Gourmelon P, Gueguen Y, Veyssiere G, Souidi M. Molecular modifications of cholesterol metabolism in the liver and the brain after chronic contamination with cesium 137. Food Chem. Toxicol. 47: 1642-1647 (2009). *

• Racine R, Gueguen Y, Gourmelon P, Veyssiere G, Souidi M. Modifications of the expression of genes involved in cerebral cholesterol metabolism in the rat following chronic ingestion of depleted uranium. J. Mol. Neurosci. 38: 159-165 (2009).

• Radford-Smith GL. Will worms really cure Crohn’s disease? Gut 54: 6-8 (2005). *

• Radha V, Vimaleswaran KS, Babu S, Deepa R, Anjana M, Ghosh S, Majumder PP, Rao MR, Mohan V. Lack of association between serum adiponectin levels and the Pro12Ala polymorphism in Asian Indians. Diabet. Med. 24: 398-402 (2007). *

• Radon K, Windstetter D, Poluda AL, Mueller B, Mutius E, Koletzko S; Chronische Autoimmunerkrankungen und Kontakt zu Tieren (Chronic Autoimmune Disease and Animal Contact) Study Group. Contact with farm animals in early life and juvenile inflammatory bowel disease: a case-control study. Pediatrics 120: 354-361 (2007). *

• Rahman P, Elder JT. Genetic epidemiology of psoriasis and psoriatic arthritis. Ann. Rheum. Dis. 64 Suppl. 2: ii37-ii39 (2005). *

• Rahme E, Barkun AN, Toubouti Y, Bardou M. The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence. Gastroenterology 125: 404-412 (2003). *

• Rahmioglu N, Andrew T, Cherkas L, Surdulescu G, Swaminathan R, Spector T, Ahmadi KR. Epidemiology and genetic epidemiology of the liver function test proteins. PLoS ONE 4: e4435 (2009). *

• Raimondi S, Bruno S, Mondelli MU, Maisonneuve P. Hepatitis C virus genotype 1b as a risk factor for hepatocellular carcinoma development: a meta-analysis. J. Hepatol. 50: 1142-1154 (2009).

• Raimondi S, Johanson H, Maisonneuve P, Gandini S. Review and meta-analysis on vitamin D receptor polymorphisms and cancer risk. Carcinogenesis 30: 1170-1180 (2009). *

• Rajan P, Kelsey KT, Schwartz JD, Bellinger DC, Weuve J, Spiro A 3rd, Sparrow D, Smith TJ, Nie H, Weisskopf MG, Hu H, Wright RO. Interaction of the delta-aminolevulinic acid dehydratase polymorphism and lead burden on cognitive function: the VA normative aging study. J. Occup. Environ. Med. 50: 1053-1061 (2008).

• Rajani R, Melin T, Bjornsson E, Broome U, Sangfelt P, Danielsson A, Gustavsson A, Grip O, Svensson H, Loof L, Wallerstedt S, Almer SH. Budd-Chiari syndrome in Sweden: epidemiology, clinical characteristics and survival - an 18-year experience. Liver Int. 29: 253-259 (2009). *

• Rajzer L, Wojas-Pelc A. The role of cytokines released by keratinocytes in psoriasis pathogenesis. Przegl. Lek. 66: 150-154 (2009).

• Rakhimova E, Wiehlmann L, Brauer AL, Sethi S, Murphy TF, Tummler B. Pseudomonas aeruginosa population biology in chronic obstructive pulmonary disease. J. Infect. Dis. 200: 1928-1935 (2009).

• Ramalle-Gomara E, Perucha M, Gonzalez MA, Quinones C, Andres J, Posada M. Cystic fibrosis mortality trends in Spain among infants and young children: 1981-2004. Eur. J. Epidemiol. 23: 523-529 (2008). *

• Rami B, Sumnik Z, Schober E, Waldhor T, Battelino T, Bratanic N, Kurti K, Lebl J, Limbert C, Madacsy L, Odink RJ, Paskova M, Soltesz G. Screening detected celiac disease in children with type 1 diabetes mellitus: effect on the clinical course (a case control study). J. Pediatr. Gastroenterol. Nutr. 41: 317-321 (2005). *

• Ramsey BW. Use of lung imaging studies as outcome measures for development of new therapies in cystic fibrosis. Proc. Am. Thorac. Soc. 4: 359-363 (2007). *

• Randerson-Moor JA, Taylor JC, Elliott F, Chang YM, Beswick S, Kukalizch K, Affleck P, Leake S, Haynes S, Karpavicius B, Marsden J, Gerry E, Bale L, Bertram C, Field H, Barth JH, Silva ID, Swerdlow A, Kanetsky PA, Barrett JH, Bishop DT, Bishop JA. Vitamin D receptor gene polymorphisms, serum 25-hydroxyvitamin D levels, and melanoma: UK case-control comparisons and a meta-analysis of published VDR data. Eur. J. Cancer 45: 3271-3281 (2009). *

• Rantner B, Kollerits B, Anderwald-Stadler M, Klein-Weigel P, Gruber I, Gehringer A, Haak M, Schnapka-Kopf M, Fraedrich G, Kronenberg F. Association between the UGT1A1 TA-repeat polymorphism and bilirubin concentration in patients with intermittent claudication: results from the CAVASIC study. Clin. Chem. 54: 851-857 (2008). *

• Raskin L, Lejbkowicz F, Barnett-Griness O, Dishon S, Almog R, Rennert G. BRCA1 breast cancer risk is modified by CYP19 polymorphisms in Ashkenazi jews. Cancer Epidemiol. Biomarkers Prev. 18: 1617-1623 (2009). *

• Rasmussen-Torvik LJ, Cushman M, Tsai MY, Zhang Y, Heckbert SR, Rosamond WD, Folsom AR. The association of alpha-fibrinogen Thr312Ala polymorphism and venous thromboembolism in the LITE study. Thromb. Res. 121: 1-7 (2007). *

• Rauch A, Nolan D, Furrer H, McKinnon E, John M, Mallal S, Gaudieri S, Gunthard HF, Schmid P, Battegay M, Hirschel B, Telenti A, James I; Swiss HIV Cohort Study. HLA-Bw4 homozygosity is associated with an impaired CD4 T cell recovery after initiation of antiretroviral therapy. Clin. Infect. Dis. 46: 1921-1925 (2008). *

• Rautava S, Ruuskanen O, Ouwehand A, Salminen S, Isolauri E. The hygiene hypothesis of atopic disease - an extended version. J. Pediatr. Gastroenterol. Nutr. 38: 378-388 (2004). *

• Rautiainen H, Salomaa V, Niemela S, Karvonen AL, Nurmi H, Isoniemi H, Farkkila M. Prevalence and incidence of primary biliary cirrhosis are increasing in Finland. Scand. J. Gastroenterol. 42: 1347-1353 (2007). *

• Ravikumara M, Sandhu BK. Epidemiology of inflammatory bowel diseases in childhood. Indian J. Pediatr. 73: 717-721 (2006). *

• Razvi S, Quittell L, Sewall A, Quinton H, Marshall B, Saiman L. Respiratory microbiology of patients with cystic fibrosis in the United States, 1995-2005. Chest 136: 1554-1560 (2009).

• Reddy BS. The Fourth DeWitt S. Goodman lecture. Novel approaches to the prevention of colon cancer by nutritional manipulation and chemoprevention. Cancer Epidemiol. Biomarkers Prev. 9: 239-247 (2000). *

• Reddy BS, Rao CV. Colon cancer: a role for cyclo-oxygenase-2-specific nonsteroidal anti-inflammatory drugs. Drugs Aging 16: 329-334 (2000).

• Reddy SI, Burakoff R. Inflammatory bowel disease in African Americans. Inflamm. Bowel Dis. 9: 380-385 (2003). *

• Regueiro M, Kip KE, Cheung O, Hegazi RA, Plevy S. Cigarette smoking and age at diagnosis of inflammatory bowel disease. Inflamm. Bowel Dis. 11: 42-47 (2005). *

• Regueiro MD. Inflammatory bowel disease. Gastroenterol. Clin. N. Am. 31: xv-xvii (2002). *

• Reich K, Kruger K, Mossner R, Augustin M. Epidemiology and clinical pattern of psoriatic arthritis in Germany: a prospective interdisciplinary epidemiological study of 1511 patients with plaque-type psoriasis. Br. J. Dermatol. 160: 1040-1047 (2009). *

• Reiner AP, Carty CL, Jenny NS, Nievergelt C, Cushman M, Stearns-Kurosawa DJ, Kurosawa S, Kuller LH, Lange LA. PROC, PROCR, and PROS1 polymorphisms, plasma anticoagulant phenotypes, and risk of cardiovascular disease and mortality in older adults: the Cardiovascular Health Study. J. Thromb. Haemost. 6: 1625-1632 (2008). *

• Reinke CM, Messick CR. Update on Clostridium difficile-induced colitis, Part 1. Am. J. Hosp. Pharm. 51: 1771-1781 (1994).

• Rellecke P, Strauer BE. Chronic inflammatory bowel disease and cardiovascular complications. Med. Klin. (Munich) 101 Suppl. 1: 56-60 (2006).

• Rellecke P, Strauer BE. Concomitant cardiovascular conditions in intestinal illness. Internist (Berl.) 48: 290-296 (2007).

• Remus N, Alcais A, Abel L. Human genetics of common mycobacterial infections. Immunol. Res. 28: 109-129 (2003).

• Rengelshausen J, Lindenmaier H, Cihlar T, Walter-Sack I, Haefeli WE, Weiss J. Inhibition of the human organic anion transporter 1 by the caffeine metabolite 1-methylxanthine. Biochem. Biophys. Res. Commun. 320: 90-94 (2004). *

• Rennert G, Almog R, Tomsho LP, Low M, Pinchev M, Chaiter Y, Bonner JD, Rennert HS, Greenson JK, Gruber SB. Colorectal polyps in carriers of the APC I1307K polymorphism. Dis. Colon Rectum 48: 2317-2321 (2005). *

• Reuben A. Alcohol and the liver. Curr. Opin. Gastroenterol. 22: 263-271 (2006).

• Rewers M. Epidemiology of celiac disease: what are the prevalence, incidence, and progression of celiac disease? Gastroenterology 128: S47-S51 (2005). *

• Rewers M, Norris J, Dabelea D. Epidemiology of type 1 diabetes mellitus. Adv. Exp. Med. Biol. 552: 219-246 (2004).

• Rex DK. Colorectal cancer surveillance, screening, and colonoscopy. American College of Gastroenterology 68th Annual Scientific Meeting and Postgraduate Course, October 10 - 15, 2003, Baltimore, Maryland (2003).

• Ricciardi R, Ogilvie JW Jr, Roberts PL, Marcello PW, Concannon TW, Baxter NN. Epidemiology of Clostridium difficile colitis in hospitalized patients with inflammatory bowel diseases. Dis. Colon Rectum 52: 40-45 (2009).

• Riccioni G, D'Orazio N, Palumbo N, Bucciarelli V, Ilio ED, Bazzano LA, Bucciarelli T. Relationship between plasma antioxidant concentrations and carotid intima-media thickness: the Asymptomatic Carotid Atherosclerotic Disease In Manfredonia study. Eur. J. Cardiovasc. Prev. Rehabil. 16: 351-357 (2009).

• Richy F, Deroisy R, Lecart MP, Hanssens L, Mawet A, Reginster JY. D-Hormone analog alfacalcidol: an update on its role in post-menopausal osteoporosis and rheumatoid arthritis management. Aging Clin. Exp. Res. 17: 133-142 (2005).

• Rigby AS, Silman AJ, Voelm L, Gregory JC, Ollier WE, Khan MA, Nepom GT, Thomson G. Investigating the HLA component in rheumatoid arthritis: an additive (dominant) mode of inheritance is rejected, a recessive mode is preferred. Genet. Epidemiol. 8: 153-175 (1991).

• Ríhova Z, Jancova E, Merta M, Tesar V. ANCA-associated renal vasculitis - epidemiology, diagnostics and treatment. Prague Med. Rep. 105: 237-260 (2004).

• Risques RA, Rabinovitch PS, Brentnall TA. Cancer surveillance in inflammatory bowel disease: new molecular approaches. Curr. Opin. Gastroenterol. 22: 382-390 (2006).

• Riyazi N, Kurreeman FA, Huizinga TW, Dekker FW, Stoeken-Rijsbergen G, Kloppenburg M. The role of interleukin 10 promoter polymorphisms in the susceptibility of distal interphalangeal osteoarthritis. J. Rheumatol. 32: 1571-1575 (2005).

• Roberts SE, Goldacre MJ, Yeates D. Trends in mortality after hospital admission for liver cirrhosis in an English population from 1968 to 1999. Gut 54: 1615-1621 (2005). *

• Robien K, Boynton A, Ulrich CM. Pharmacogenetics of folate-related drug targets in cancer treatment. Pharmacogenomics 6: 673-689 (2005).

• Robinson D Jr, Hackett M, Wong J, Kimball AB, Cohen R, Bala M; The IMID Study Group. Co-occurrence and comorbidities in patients with immune-mediated inflammatory disorders: an exploration using US healthcare claims data, 2001-2002. Curr. Med. Res. Opin. 22: 989-1000 (2006).

• Robinson JG. Should we use PPAR agonists to reduce cardiovascular risk? PPAR Res. 2008: 891425 (2008). *

• Robinson JG. Update on PPAR agonists: the clinical significance of FIELD and PROACTIVE. Curr. Atheroscler. Rep. 9: 64-71 (2007).

• Robinson JG, Stone NJ. Antiatherosclerotic and antithrombotic effects of omega-3 fatty acids. Am. J. Cardiol. 98: S39-S49 (2006). *

• Roder DM. The epidemiology of gastric cancer. Gastric Cancer 5 Suppl. 1: 5-11 (2002).

• Rodrigo Saez L, Valerdiz Casasola CS, Rodriguez Garcia M, Riera Velasco JR, Perez Alvarez R, Linares Rodriguez A. Epidemiology of primary biliary cirrhosis in Asturias. Med. Clin. (Barc.) 88: 486-489 (1987).

• Rodriguez-D'Jesus A, Casellas F, Malagelada JR. Epidemiology of inflammatory bowel disease in the elderly. Gastroenterol. Hepatol. 31: 269-273 (2008).

• Rodriguez-Moranta F, Castells A, Andreu M, Pinol V, Castellvi-Bel S, Alenda C, Llor X, Xicola RM, Jover R, Paya A, Bessa X, Balaguer F, Cubiella J, Arguello L, Morillas JD, Bujanda L. Clinical performance of original and revised Bethesda guidelines for the identification of MSH2/MLH1 gene carriers in patients with newly diagnosed colorectal cancer: proposal of a new and simpler set of recommendations. Am. J. Gastroenterol. 101: 1104-1111 (2006). *

• Roelofzen JH, Aben KK, Oldenhof UT, Coenraads PJ, Alkemade HA, van de Kerkhof PC, van der Valk PG, Kiemeney LA. No increased risk of cancer after coal tar treatment in patients with psoriasis or eczema. J. Invest. Dermatol. Dec 17 [Epub ahead of print] (2009). *

• Romberg-Camps MJ, Dagnelie PC, Kester AD, Hesselink-van de Kruijs MA, Cilissen M, Engels LG, Van Deursen C, Hameeteman WH, Wolters FL, Russel MG, Stockbrugger RW. Influence of phenotype at diagnosis and of other potential prognostic factors on the course of inflammatory bowel disease. Am. J. Gastroenterol. 104: 371-383 (2009).

• Ronaldson KJ, McNeil JJ. Improving drug safety by locating genetic markers for hypersensitivity reactions. Med. J. Aust. 190: 641-643 (2009).

• Rooney AP, Swezey JL, Friedman R, Hecht DW, Maddox CW. Analysis of core housekeeping and virulence genes reveals cryptic lineages of Clostridium perfringens that are associated with distinct disease presentations. Genetics 172: 2081-2092 (2006). *

• Rose CD. Epidemiology of juvenile rheumatoid arthritis in the Americas: an update. J. Clin. Rheumatol. 12: 129-130 (2006).

• Rosell M, Wesley AM, Rydin K, Klareskog L, Alfredsson L; the EIRA study group. Dietary fish and fish oil and the risk of rheumatoid arthritis. Epidemiology 20: 896-901 (2009).

• Rosell MS, Lloyd-Wright Z, Appleby PN, Sanders TA, Allen NE, Key TJ. Long-chain n-3 polyunsaturated fatty acids in plasma in British meat-eating, vegetarian, and vegan men. Am. J. Clin. Nutr. 82: 327-334 (2005). *

• Rosenthal P. Digestive disease week 2000. American association for the study of liver diseases. IDrugs 3: 868-871 (2000).

• Ross AS, Waxman I. Flat and depressed neoplasms of the colon in Western populations. Am. J. Gastroenterol. 101: 172-180 (2006). *

• Rostom A, Murray JA, Kagnoff MF. American Gastroenterological Association Technical Review (AGA) Institute on the Diagnosis and Management of Celiac Disease. Gastroenterology 131: 1981-2002 (2006). *

• Rothman N, Skibola CF, Wang SS, Morgan G, Lan Q, Smith MT, Spinelli JJ, Willett E, De Sanjose S, Cocco P, Berndt SI, Brennan P, Brooks-Wilson A, Wacholder S, Becker N, Hartge P, Zheng T, Roman E, Holly EA, Boffetta P, Armstrong B, Cozen W, Linet M, et al. Genetic variation in TNF and IL10 and risk of non-Hodgkin lymphoma: a report from the InterLymph Consortium. Lancet Oncol. 7: 27-38 (2006).

• Rougier P, Mitry E. Epidemiology, treatment and chemoprevention in colorectal cancer. Ann. Oncol. 14 Suppl. 2: ii3-5 (2003). *

• Rousseau K, Byrne C, Griesinger G, Leung A, Chung A, Hill AS, Swallow DM. Allelic association and recombination hotspots in the mucin gene (MUC) complex on chromosome 11p15.5. Ann. Hum. Genet. 71: 561-569 (2007). *

• Rovner AJ, O'Brien KO. Hypovitaminosis D among healthy children in the United States: a review of the current evidence. Arch. Pediatr. Adolesc. Med. 162: 513-519 (2008).

• Rovner AJ, Zemel BS. Re: prevalence of long bone fractures in pediatric inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 45: 269-271 (2007). *

• Royston P. A strategy for modelling the effect of a continuous covariate in medicine and epidemiology. Stat. Med. 19: 1831-1847 (2000). *

• Rozman B, Novljan MP, Hocevar A, Ambrozic A, Zigon P, Kveder T, Tomsic M. Epidemiology and diagnostics of primary Sjogren's syndrome. Reumatizam 51: 9-12 (2004).

• Rubin DT, Cruz-Correa MR, Gasche C, Jass JR, Lichtenstein GR, Montgomery EA, Riddell RH, Rutter MD, Ullman TA, Velayos FS, Itzkowitz S; 5-ASA in Colorectal Cancer Prevention Meeting Group. Colorectal cancer prevention in inflammatory bowel disease and the role of 5-aminosalicylic acid: a clinical review and update. Inflamm. Bowel Dis. 14: 265-274 (2008). *

• Rubin RH. Cytomegalovirus infection in the liver transplant recipient. Epidemiology, pathogenesis, and clinical management. Clin. Liver Dis. 1: 439-452, x (1997).

• Ruddle NH, Akirav EM. Secondary lymphoid organs: responding to genetic and environmental cues in ontogeny and the immune response. J. Immunol. 183: 2205-2212 (2009).

• Ruden C. Science and policy in risk assessments of chlorinated ethenes. Ann. N. Y. Acad. Sci. 1076: 191-206 (2006). *

• Ruder AM. Potential health effects of occupational chlorinated solvent exposure. Ann. N. Y. Acad. Sci. 1076: 207-227 (2006). *

• Rufo PA, Bousvaros A. Challenges and progress in pediatric inflammatory bowel disease. Curr. Opin. Gastroenterol. 23: 406-412 (2007).

• Rugbjerg K, Friis S, Ritz B, Schernhammer ES, Korbo L, Olsen JH. Autoimmune disease and risk for Parkinson disease. A population-based case-control study. Neurology 73: 1462-1468 (2009).

• Ruhl CE, Everhart JE. Epidemiology of nonalcoholic fatty liver. Clin. Liver Dis. 8: 501-519 (2004).

• Ruiz-Narvaez EA, Kraft P, Campos H. Ala12 variant of the peroxisome proliferator-activated receptor-gamma gene (PPARG) is associated with higher polyunsaturated fat in adipose tissue and attenuates the protective effect of polyunsaturated fat intake on the risk of myocardial infarction. Am. J. Clin. Nutr. 86: 1238-1242 (2007). *

• Russel MG. Medical treatment of inflammatory bowel disease - current clinical practice. Business Briefing: European Gastroenterology Review, p. 25-26 (2005). *

• Russel MG, Engels LG, Muris JW, Limonard CB, Volovics A, Brummer RJ, Stockbrugger RW. Modern life' in the epidemiology of inflammatory bowel disease: a case-control study with special emphasis on nutritional factors. Eur. J. Gastroenterol. Hepatol. 10: 243-249 (1998).

• Russel MG, Stockbrugger RW. Epidemiology of inflammatory bowel disease: an update. Scand. J. Gastroenterol. 31: 417-427 (1996).

• Rutherford AE, Pratt DS. Cholestasis and cholestatic syndromes. Curr. Opin. Gastroenterol. 22: 209-214 (2006). *

• Rutjes AW, Nuesch E, Reichenbach S, Juni P. S-Adenosylmethionine for osteoarthritis of the knee or hip. Cochrane Database Syst. Rev. 4: CD007321 (2009). *

• Rybicki BA, Hirst K, Iyengar SK, Barnard JG, Judson MA, Rose CS, Donohue JF, Kavuru MS, Rabin DL, Rossman MD, Baughman RP, Elston RC, Maliarik MJ, Moller DR, Newman LS, Teirstein AS, Iannuzzi MC. A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study. Sarcoidosis Vasc. Diffuse Lung Dis. 22: 115-122 (2005).

• Rybicki BA, Iannuzzi MC. Epidemiology of sarcoidosis: recent advances and future prospects. Semin. Respir. Crit. Care Med. 28: 22-35 (2007).

• Rybicki BA, Sinha R, Iyengar S, Gray-McGuire C, Elston RC, Iannuzzi MC. Genetic linkage analysis of sarcoidosis phenotypes: the sarcoidosis genetic analysis (SAGA) study. Genes Immun. 8: 379-386 (2007). *

• Rybicki BA, Walewski JL, Maliarik MJ, Kian H, Iannuzzi MC; ACCESS Research Group. The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites. Am. J. Hum. Genet. 77: 491-499 (2005). *

• Rzehak P, Heinrich J, Klopp N, Schaeffer L, Hoff S, Wolfram G, Illig T, Linseisen J. Evidence for an association between genetic variants of the fatty acid desaturase 1 fatty acid desaturase 2 (FADS1 FADS2) gene cluster and the fatty acid composition of erythrocyte membranes. Br. J. Nutr. 101: 20-26 (2009). *

• Saab R, Furman WL. Epidemiology and management options for colorectal cancer in children. Paediatr. Drugs 10: 177-192 (2008).

• Saad AA, Ashcroft DM, Watson KD, Symmons DP, Noyce PR, Hyrich KL; on behalf of the BSRBR. Efficacy and safety of anti-TNF therapies in psoriatic arthritis: an observational study from the British Society for Rheumatology Biologics Register. Rheumatology (Oxford) Jan 7 [Epub ahead of print] (2010). *

• Saad AA, Symmons DP, Noyce PR, Ashcroft DM. Risks and benefits of tumor necrosis factor-alpha inhibitors in the management of psoriatic arthritis: systematic review and metaanalysis of randomized controlled trials. J. Rheumatol. 35: 883-890 (2008). *

• Sachdeva A, Nagpal J. Efficacy of bovine lactoferrin in Helicobacter pylori eradication. Aliment. Pharmacol. Ther. 29: 720-730 (2009). *

• Sadovnick AD, Bulman D, Ebers GC. Parent-child concordance in multiple sclerosis. Ann. Neurol. 29: 252-255 (1991).

• Sagiv-Friedgut K, Karban A, Weiss B, Shaoul R, Shamir R, Bujanover Y, Reif S, Boaz M, Shani I, Levine A, Leshinsky-Silver E. Early-onset Crohn disease is associated with male sex and a polymorphism in the IL-6 promoter. J. Pediatr. Gastroenterol. Nutr. 50: 22-26 (2010).

• Saiman L, Garber E. Infection control in cystic fibrosis: barriers to implementation and ideas for improvement. Curr. Opin. Pulm. Med. Jul 30 [Epub ahead of print] (2009).

• Saito YA, Locke GR 3rd, Weaver AL, Zinsmeister AR, Talley NJ. Diet and functional gastrointestinal disorders: a population-based case-control study. Am. J. Gastroenterol. 100: 2743-2748 (2005). *

• Sakamoto N, Kono S, Wakai K, Fukuda Y, Satomi M, Shimoyama T, Inaba Y, Miyake Y, Sasaki S, Okamoto K, Kobashi G, Washio M, Yokoyama T, Date C, Tanaka H; The Epidemiology Group of the Research Committee on Inflammatory Bowel Disease in Japan. Dietary risk factors for inflammatory bowel disease: a multicenter case-control study in Japan. Inflamm. Bowel Dis. 11: 154-163 (2005). *

• Sakoda LC, Blackston CR, Xue K, Doherty JA, Ray RM, Lin MG, Stalsberg H, Gao DL, Feng Z, Thomas DB, Chen C. Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women. Breast Cancer Res. Treat. 109: 143-155 (2008).

• Sakugawa H, Nakasone H, Nakayoshi T, Yamashiro T, Maeshiro T, Kobashigawa K, Kinjo F, Saito A, Zukeran H, Nakanuma Y, Ohba K. Epidemiology of primary biliary cirrhosis among women with elevated gamma-glutamyl transpeptidase levels in Okinawa, Japan. Hepatol. Res. 26: 330-336 (2003).

• Salanti G, Ioannidis JP. Synthesis of observational studies should consider credibility ceilings. J. Clin. Epidemiol. 62: 115-122 (2009).

• Saleh MM, Abdo KR. Intrahepatic cholestasis of pregnancy: review of the literature and evaluation of current evidence. J. Womens Health (Larchmt.) 16: 833-841 (2007).

• Salkic NN, Pavlovic-Calic N, Gegic A, Jovanovic P, Basic M. Ulcerative colitis in the Tuzla region of Bosnia and Herzegovina between 1995 and 2006: epidemiological and clinical characteristics. Eur. J. Gastroenterol. Hepatol. May 23 [Epub ahead of print] (2009).

• Sallmann DS, Fiebig B, Hedrich CM, Heubner G, Gahr M. Systemic lupus erythematosus in children and adolescents. Z. Rheumatol. 65: 576-586 (2006).

• Salonen A, Palva A, de Vos WM. Microbial functionality in the human intestinal tract. Front. Biosci. 14: 3074-3084 (2009).

• Salvarani C, Fries W. Clinical features and epidemiology of spondyloarthritides associated with inflammatory bowel disease. World J. Gastroenterol. 15: 2449-2455 (2009). *

• San-Juan OD, Castro-Macias JI. Chronic inflammatory demyelinating polyradiculoneuropathy. 10 years' experience in a Mexican centre. Rev. Neurol. 46: 656-659 (2008).

• Sanchez-Nino MD, Sanz AB, Ihalmo P, Lassila M, Holthofer H, Mezzano S, Aros C, Groop PH, Saleem MA, Mathieson PW, Langham R, Kretzler M, Nair V, Lemley KV, Nelson RG, Mervaala E, Mattinzoli D, Rastaldi MP, Ruiz-Ortega M, Martin-Ventura JL, Egido J, et al. The MIF receptor CD74 in diabetic podocyte injury. J. Am. Soc. Nephrol. 20: 353-362 (2009).

• Sandhu MS, Weedon MN, Fawcett KA, Wasson J, Debenham SL, Daly A, Lango H, Frayling TM, Neumann RJ, Sherva R, Blech I, Pharoah PD, Palmer CN, Kimber C, Tavendale R, Morris AD, McCarthy MI, Walker M, Hitman G, Glaser B, Permutt MA, Hattersley AT, et al. Common variants in WFS1 confer risk of type 2 diabetes. Nat. Genet. 39: 951-953 (2007). *

• Sandler RS, Golden AL. Epidemiology of Crohn's disease. J. Clin. Gastroenterol. 8: 160-165 (1986).

• Sands BE, Grabert S. Epidemiology of inflammatory bowel disease and overview of pathogenesis. Med. Health R.I. 92: 73-77 (2009).

• Sangiovanni JP, Chew EY. The role of omega-3 long-chain polyunsaturated fatty acids in health and disease of the retina. Prog. Retin. Eye Res. 24: 87-138 (2005).

• Sankaranarayanan R, Mathew B. Retinoids as cancer-preventive agents. IARC Sci. Publ. 139: 47-59 (1996).

• Santo Tomas LH. Beryllium hypersensitivity and chronic beryllium lung disease. Curr. Opin. Pulm. Med. 15: 165-169 (2009).

• Sarid R, Klepfish A, Schattner A. Virology, pathogenetic mechanisms, and associated diseases of Kaposi sarcoma-associated herpesvirus (human herpesvirus 8). Mayo Clin. Proc. 77: 941-949 (2002). *

• Saro Gismera C, Riestra Menendez S, Sanchez Fernandez R, Milla Crespo A, Lacort Fernandez M, Arguelles Fernandez G, Chobak Z, Florido Mancheno JI, Anton Magarzo JL, Altadill Arregui A, Vizoso F, Pineda Garcia E, Fernandez de Ocariz Archs E, et al. Epidemiology in inflammatory bowel disease in five areas of Asturias, Spain. An. Med. Interna. 20: 232-238 (2003).

• Sasson SC, Smith S, Seddiki N, Zaunders JJ, Bryant A, Koelsch KK, Weatherall C, Munier ML, McGinley C, Yeung J, Mulligan SP, Moore J, Cooper DA, Milliken S, Kelleher AD. IL-7 receptor is expressed on adult pre-B-cell acute lymphoblastic leukemia and other B-cell derived neoplasms and correlates with expression of proliferation and survival markers. Cytokine Jan 7 [Epub ahead of print] (2010).

• Sasson SC, Zaunders JJ, Kelleher AD. The IL-7/IL-7 receptor axis: understanding its central role in T-cell homeostasis and the challenges facing its utilization as a novel therapy. Curr. Drug Targets 7: 1571-1582 (2006).

• Satia JA, Littman A, Slatore CG, Galanko JA, White E. Long-term use of beta-carotene, retinol, lycopene, and lutein supplements and lung cancer risk: results from the VITamins And Lifestyle (VITAL) Study. Am. J. Epidemiol. 169: 815-828 (2009).

• Satia JA, Littman A, Slatore CG, Galanko JA, White E. Associations of herbal and specialty supplements with lung and colorectal cancer risk in the VITamins And Lifestyle Study. Cancer Epidemiol. Biomarkers Prev. 18: 1419-1428 (2009).

• Satsangi J, Campbell H, Dunlop MG, Porteous ME. Molecular genetics in gastroenterology: from research success to clinical application? Nat. Clin. Pract. Gastroenterol. Hepatol. 2: 118-119 (2005). *

• Sauer CG, Kugathasan S. Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. Med. Clin. North Am. 94: 35-52 (2010).

• Sauer CG, Kugathasan S. Pediatric inflammatory bowel disease: highlighting pediatric differences in IBD. Gastroenterol. Clin. North Am. 38: 611-628 (2009).

• Saurenmann RK, Rose JB, Tyrrell P, Feldman BM, Laxer RM, Schneider R, Silverman ED. Epidemiology of juvenile idiopathic arthritis in a multiethnic cohort: ethnicity as a risk factor. Arthritis Rheum. 56: 1974-1984 (2007). *

• Sayed-Tabatabaei FA, Oostra BA, Isaacs A, van Duijn CM, Witteman JC. ACE polymorphisms. Circ. Res. 98: 1123-1133 (2006). *

• Schackman BR, Scott CA, Walensky RP, Losina E, Freedberg KA, Sax PE. The cost-effectiveness of HLA-B*5701 genetic screening to guide initial antiretroviral therapy for HIV. AIDS 22: 2025-2033 (2008).

• Schafer T. Epidemiology of psoriasis. Review and the German perspective. Dermatology 212: 327-337 (2006).

• Schell LM, Gallo MV. Relationships of putative endocrine disruptors to human sexual maturation and thyroid activity in youth. Physiol. Behav. Sep 30 [Epub ahead of print] (2009).

• Schell LM, Gallo MV, Ravenscroft J, Decaprio AP. Persistent organic pollutants and anti-thyroid peroxidase levels in Akwesasne Mohawk young adults. Environ. Res. 109: 86-92 (2009). *

• Schenk JM, Riboli E, Chatterjee N, Leitzmann MF, Ahn J, Albanes D, Reding DJ, Wang Y, Friesen MD, Hayes RB, Peters U. Serum retinol and prostate cancer risk: a nested case-control study in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol. Biomarkers Prev. 18: 1227-1231 (2009).

• Scherag A, Hebebrand J, Schafer H, Muller HH. Flexible designs for genomewide association studies. Biometrics 65: 815-821 (2009). *

• Schiff MH, Burmester GR, Kent JM, Pangan AL, Kupper H, Fitzpatrick SB, Donovan C. Safety analyses of adalimumab (HUMIRA(R)) in global clinical trials and US postmarketing surveillance of patients with rheumatoid arthritis. Ann. Rheum. Dis. 65: 889-894 (2006). *

• Schilsky ML, Fink S. Inherited metabolic liver disease. Curr. Opin. Gastroenterol. 22: 215-222 (2006).

• Schirmer M, Rosenberger A, Klein K, Kulle B, Toliat MR, Nurnberg P, Zanger UM, Wojnowski L. Sex-dependent genetic markers of CYP3A4 expression and activity in human liver microsomes. Pharmacogenomics 8: 443-453 (2007).

• Schlager SI, Hanauer SB. New therapeutic approaches to peptic ulcer disease: the role of Helicobacter pylori. Am. J. Ther. 3: 586-596 (1996).

• Schmitt J, Ford DE. Understanding the relationship between objective disease severity, psoriatic symptoms, illness-related stress, health-related quality of life and depressive symptoms in patients with psoriasis - a structural equations modeling approach. Gen. Hosp. Psychiatry 29: 134-140 (2007).

• Schnappinger M, Sausenthaler S, Linseisen J, Hauner H, Heinrich J. Fish consumption, allergic sensitisation and allergic diseases in adults. Ann. Nutr. Metab. 54: 67-74 (2009).

• Schneeweiss S, Korzenik J, Solomon DH, Canning C, Lee J, Bressler B. Infliximab and other immunomodulating drugs in patients with inflammatory bowel disease and the risk of serious bacterial infections. Aliment. Pharmacol. Ther. 30: 253-264 (2009). *

• Schneider V, Suissa S. Antibiotic use and the development of Crohn's disease: methodological issues. Gut 53: 1544 (2004). *

• Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, Labute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM. Escape from the dominant HLA-B27 restricted CTL response in Gag is associated with a dramatic reduction in HIV-1 replication. J. Virol. 81: 12382-12393 (2007). *

• Schoen RE, Pinsky PF, Weissfeld JL, Yokochi LA, Reding DJ, Hayes RB, Church T, Yurgalevich S, Doria-Rose VP, Hickey T, Riley T, Berg CD. Utilization of surveillance colonoscopy in community practice. Gastroenterology 138: 73-81 (2010). *

• Schoenfeld PS. Pro. EBM: an invaluable tool for medical practice. Am. J. Gastroenterol. 103: 2965-2967 (2008). *

• Scholz T, Karlsen TH, Sanengen T, Schrumpf E, Foss A, Line PD, Boberg KM, Jorgensen PF, Fosby B, Bentdal O, Ostensen AB, Osnes S, Riddervold F, Haugaa H, Hausken J, Bergmann JB, Foss S, Bjoro K. Liver transplantation in Norway through 25 years. Tidsskr. Nor. Laegeforen. 129: 2587-2592 (2009).

• Schottenfeld D, Beebe-Dimmer JL, Vigneau FD. The epidemiology and pathogenesis of neoplasia in the small intestine. Ann. Epidemiol. 19: 58-69 (2009).

• Schramm C, Herkel J, Beuers U, Kanzler S, Galle PR, Lohse AW. Pregnancy in autoimmune hepatitis: outcome and risk factors. Am. J. Gastroenterol. 101: 556-560 (2006). *

• Schreibman I, Regev A. Recurrent primary biliary cirrhosis after liver transplantation - the disease and its management. MedGenMed. 8: 30 (2006). *

• Schrumpf E, Boberg KM. Epidemiology of primary sclerosing cholangitis. Best Pract. Res. Clin. Gastroenterol. 15: 553-562 (2001). *

• Schrumpf E, Jorgensen KK, Boberg KM. Primary sclerosing cholangitis, inflammatory bowel disease and treatment options. Falk Workshop "Primary Sclerosing Cholangitis: Complications and Consequences", Moscow (Russia), June 11, 2006, p. 15-16 (2006). *

• Schulte CM. Bone disease in inflammatory bowel disease. Aliment. Pharmacol. Ther. 20 Suppl. 4: 43-49 (2004). *

• Schulz A, Fischer C, Chang-Claude J, Beckmann L. Entropy-supported marker selection and Mantel statistics for haplotype sharing analysis. Genet. Epidemiol. Feb 11 [Epub ahead of print] (2010).

• Schuppan D, Dennis MD, Kelly CP. Celiac disease: epidemiology, pathogenesis, diagnosis, and nutritional management. Nutr. Clin. Care 8: 54-69 (2005).

• Schurks M, Zee RY, Buring JE, Kurth T. Interrelationships among the MTHFR 677C>T polymorphism, migraine, and cardiovascular disease. Neurology 71: 505-513 (2008).

• Schwartz AV, Sellmeyer DE. Effect of thiazolidinediones on skeletal health in women with type 2 diabetes. Expert Opin. Drug Saf. 7: 69-78 (2008).

• Schwartz AV, Sellmeyer DE, Vittinghoff E, Palermo L, Lecka-Czernik B, Feingold KR, Strotmeyer ES, Resnick HE, Carbone L, Beamer BA, Won Park S, Lane NE, Harris TB, Cummings SR. Thiazolidinedione (TZD) use and bone loss in older diabetic adults. J. Clin. Endocrinol. Metab. 91: 3349-3354 (2006). *

• Schwartzbaum J, Ahlbom A, Malmer B, Lonn S, Brookes AJ, Doss H, Debinski W, Henriksson R, Feychting M. Polymorphisms associated with asthma are inversely related to glioblastoma multiforme. Cancer Res. 65: 6459-6465 (2005). *

• Scotet V, Gillet D, Dugueperoux I, Audrezet MP, Bellis G, Garnier B, Roussey M, Rault G, Parent P, De Braekeleer M, Ferec C; Reseau Mucoviscidose Bretagne et Pays de Loire. Spatial and temporal distribution of cystic fibrosis and of its mutations in Brittany, France: a retrospective study from 1960. Hum. Genet. 111: 247-254 (2002).

• Scotet V, Le Gac G, Merour MC, Mercier AY, Chanu B, Ka C, Mura C, Nousbaum JB, Ferec C. Impact of HFE genetic testing on clinical presentation of hereditary hemochromatosis: new epidemiological data. BMC Med. Genet. 6: 24 (2005). *

• Seagroatt V. MMR vaccine and Crohn's disease: ecological study of hospital admissions in England, 1991 to 2002. BMJ 330: 1120-1121 (2005). *

• Seagroatt V, Goldacre MJ. Crohn's disease, ulcerative colitis, and measles vaccine in an English population, 1979-1998. J. Epidemiol. Community Health 57: 883-887 (2003).

• Seaman H, Ballard K, Wright J, de Vries C. Endometriosis and its coexistence with irritable bowel syndrome and pelvic inflammatory disease: findings from a national case-control study-Part 2. BJOG 115: 1392-1396 (2008).

• Seeger JD, Lanza LL, West WA, Fernandez C, Rivero E. Pregnancy and pregnancy outcome among women with inflammatory skin diseases. Dermatology 214: 32-39 (2007).

• Seiderer J, Brand S, Herrmann KA, Schnitzler F, Hatz R, Crispin A, Pfennig S, Schoenberg SO, Goke B, Lohse P, Ochsenkuhn T. Predictive value of the CARD15 variant 1007fs for the diagnosis of intestinal senoses and the need for surgery in Crohn's disease in clinical practice: results of a prospective study. Inflamm. Bowel Dis. 12: 1114-1121 (2006). *

• Seidman EG. Recent advances in the diagnosis and treatment of pediatric inflammatory bowel disease. Curr. Gastroenterol. Rep. 2: 248-252 (2000).

• Sekimoto M, Takada T, Kawarada Y, Nimura Y, Yoshida M, Mayumi T, Miura F, Wada K, Hirota M, Yamashita Y, Strasberg S, Pitt HA, Belghiti J, de Santibanes E, Gadacz TR, Hilvano SC, Kim SW, Liau KH, Fan ST, Belli G, Sachakul V. Need for criteria for the diagnosis and severity assessment of acute cholangitis and cholecystitis: Tokyo Guidelines. J. Hepatobiliary Pancreat. Surg. 14: 11-14 (2007). *

• Selhub J, Morris MS, Jacques PF. In vitamin B12 deficiency, higher serum folate is associated with increased total homocysteine and methylmalonic acid concentrations. Proc. Natl. Acad. Sci. U.S.A. 104: 19995-20000 (2007). *

• Selmi C. Environmental factors in primary biliary cirrhosis. Hepatol. Res. 37 Suppl. 3: S370-S376 (2007). *

• Selmi C, Cocchi CA, Zuin M, Gershwin ME. The chemical pathway to primary biliary cirrhosis. Clin. Rev. Allergy Immunol. 36: 23-29 (2009). *

• Selmi C, Gershwin ME, Lindor KD, Worman HJ, Gold EB, Watnik M, Utts J, Invernizzi P, Kaplan MM, Vierling JM, Bowlus CL, Silveira MG, Bossi I; USA PBC Epidemiology Group. Quality of life and everyday activities in patients with primary biliary cirrhosis. Hepatology 46: 1836-1843 (2007). *

• Selmi C, Invernizzi P, Keefe EB, Coppel RL, Podda M, Rossaro L, Ansari AA, Gershwin ME. Epidemiology and pathogenesis of primary biliary cirrhosis. J. Clin. Gastroenterol. 38: 264-271 (2004).

• Selmi C, Invernizzi P, Zuin M, Podda M, Gershwin ME. Genetics and geoepidemiology of primary biliary cirrhosis: following the footprints to disease etiology. Semin. Liver Dis. 25: 265-280 (2005).

• Selmi C, Tsuneyama K. Nutrition, geoepidemiology, and autoimmunity. Autoimmun. Rev. Dec 4 [Epub ahead of print] (2009).

• Selva-O'Callaghan A, Redondo-Benito A, Trallero-Araguas E, Martinez-Gomez X, Palou E, Vilardell-Tarres M. Clinical significance of thyroid disease in patients with inflammatory myopathy. Medicine (Baltimore) 86: 293-298 (2007).

• Seng KC, Seng CK. The success of the genome-wide association approach: a brief story of a long struggle. Eur. J. Hum. Genet. 16: 554-564 (2008). *

• Senore C, Segnan N, Bonelli L, Sciallero S, Pennazio M, Angioli D, Crosta C, Gasperoni S, Malfitana G; SCORE Working Group. Predicting proximal advanced neoplasms at screening sigmoidoscopy. Dis. Colon Rectum 47: 1331-1340 (2004).

• Sethi A, Stravitz RT. Review article: medical management of the liver transplant recipient - a primer for non-transplant doctors. Aliment. Pharmacol. Ther. 25: 229-245 (2007). *

• Setty AR, Choi HK. Psoriatic arthritis epidemiology. Curr. Rheumatol. Rep. 9: 449-454 (2007).

• Severinski S, Banac S, Severinski NS, Ahel V, Cvijovic K. Epidemiology and clinical characteristics of thyroid dysfunction in children and adolescents with type 1 diabetes. Coll. Antropol. 33: 273-279 (2009).

• Sevilla I, Garrido JM, Geijo M, Juste RA. Pulsed-field gel electrophoresis profile homogeneity of Mycobacterium avium subsp. paratuberculosis isolates from cattle and heterogeneity of those from sheep and goats. BMC Microbiol. 7: 18 (2007). *

• Sevilla I, Li L, Amonsin A, Garrido JM, Geijo MV, Kapur V, Juste RA. Comparative analysis of Mycobacterium avium subsp. paratuberculosis isolates from cattle, sheep and goats by short sequence repeat and pulsed-field gel electrophoresis typing. BMC Microbiol. 8: 204 (2008). *

• Shaffer EA. Epidemiology of gallbladder stone disease. Best Pract. Res. Clin. Gastroenterol. 20: 981-996 (2006).

• Shahar E, Folsom AR, Melnick SL, Tockman MS, Comstock GW, Gennaro V, Higgins MW, Sorlie PD, Ko WJ, Szklo M; Atherosclerosis Risk in Communities Study Investigators. Dietary n-3 polyunsaturated acids and smoking-related chronic obstructive pulmonary disease. Am. J. Epidemiol. 168: 796-801 (2008). *

• Shaheen NJ, Hansen RA, Morgan DR, Gangarosa LM, Ringel Y, Thiny MT, Russo MW, Sandler RS. The burden of gastrointestinal and liver diseases, 2006. Am. J. Gastroenterol. 101: 2128-2138 (2006). *

• Shaib Y, Davila J, Naumann C, El-Serag H. The impact of curative intent surgery on the survival of pancreatic cancer patients: a U.S. population-based study. Am. J. Gastroenterol. 102: 1377-1382 (2007). *

• Shaib Y, El-Serag HB. The epidemiology of cholangiocarcinoma. Semin. Liver Dis. 24: 115-125 (2004).

• Shaib YH, Davila JA, McGlynn K, El-Serag HB. Rising incidence of intrahepatic cholangiocarcinoma in the United States: a true increase? J. Hepatol. 40: 472-477 (2004). *

• Shaib YH, El-Serag HB, Davila JA, Morgan R, McGlynn KA. Risk factors of intrahepatic cholangiocarcinoma in the United States: a case-control study. Gastroenterology 128: 620-626 (2005). *

• Shakery K, Reich K. Psoriasis - clinical picture and current therapy. Med. Monatsschr. Pharm. 32: 335-344 (2009).

• Shanahan F, Bernstein CN. The evolving epidemiology of inflammatory bowel disease. Curr. Opin. Gastroenterol. 25: 301-305 (2009).

• Shao W, Lobashevsky ES, Kaslow RA, Dorak MT. MICA intron 1 sequences of conserved extended HLA haplotypes: implications for sequencing-based typing. Genes Immun. 5: 371-374 (2004). *

• Shao W, Tang J, Song W, Wang C, Li Y, Wilson CM, Kaslow RA. CCL3L1 and CCL4L1: variable gene copy number in adolescents with and without human immunodeficiency virus type 1 (HIV-1) infection. Genes Immun. 8: 224-231 (2007). *

• Shapira Y, Agmon-Levin N, Shoenfeld Y. Defining and analyzing geoepidemiology and human autoimmunity. J. Autoimmun. Dec 22 [Epub ahead of print] (2009).

• Shapiro AE, Tukahebwa EM, Kasten J, Clarke SE, Magnussen P, Olsen A, Kabatereine NB, Ndyomugyenyi R, Brooker S. Epidemiology of helminth infections and their relationship to clinical malaria in southwest Uganda. Trans. R. Soc. Trop. Med. Hyg. 99: 18-24 (2005). *

• Sharma L, Kapoor D, Issa S. Epidemiology of osteoarthritis: an update. Curr. Opin. Rheumatol. 18: 147-156 (2006).

• Sharma M, Ansari MT, Abou-Setta AM, Soares-Weiser K, Ooi TC, Sears M, Yazdi F, Tsertsvadze A, Moher D. Systematic review: comparative effectiveness and harms of combinations of lipid-modifying agents and high-dose statin monotherapy. Ann. Intern. Med. Aug 31 [Epub ahead of print] (2009).

• Sharma M, Ansari MT, Abou-Setta AM, Soares-Weiser K, Ooi TC, Sears M, Yazdi F, Tsertsvadze A, Moher D. Systematic review: comparative effectiveness and harms of combination therapy and monotherapy for dyslipidemia. Ann. Intern. Med. 151: 622-630 (2009).

• Sharp L, Little J. Polymorphisms in genes involved in folate metabolism and colorectal neoplasia: a HuGE review. Am. J. Epidemiol. 159: 423-443 (2004). *

• Shchegolev AI, Pavlov KA, Dubova EA, Egorov VI. Autoimmune pancreatitis. Arkh. Patol. 70: 46-51 (2008).

• Shephard ND, Abo R, Rigas SH, Frank B, Lin WY, Brock IW, Shippen A, Balasubramanian SP, Reed MW, Bartram CR, Meindl A, Schmutzler RK, Engel C, Burwinkel B, Cannon-Albright LA, Allen-Brady K, Camp NJ, Cox A. A breast cancer risk haplotype in the caspase-8 gene. Cancer Res. 69: 2724-2728 (2009). *

• Sherman M. Hepatocellular carcinoma: epidemiology, risk factors, and screening. Semin. Liver Dis. 25: 143-154 (2005).

• Sherman PM, Ossa JC, Wine E. Bacterial infections: new and emerging enteric pathogens. Curr. Opin. Gastroenterol. 26: 1-4 (2010).

• Shete S, Hosking FJ, Robertson LB, Dobbins SE, Sanson M, Malmer B, Simon M, Marie Y, Boisselier B, Delattre JY, Hoang-Xuan K, Hallani SE, Idbaih A, Zelenika D, Andersson U, Henriksson R, Bergenheim AT, Feychting M, Lonn S, et al. Genome-wide association study identifies five susceptibility loci for glioma. Nat. Genet. 41: 899-904 (2009). *

• Shigemitsu H, Afshar K. Nocturnal asthma. Curr. Opin. Pulm. Med. 13: 49-55 (2007).

• Shimazu T, Tsubono Y, Kuriyama S, Ohmori K, Koizumi Y, Nishino Y, Shibuya D, Tsuji I. Coffee consumption and the risk of primary liver cancer: pooled analysis of two prospective studies in Japan. Int. J. Cancer 116: 150-154 (2005). *

• Shimokata H, Ando F. Genomic approaches to bone and joint diseases. Current state of disease genome research: osteoporosis. Clin. Calcium 18: 155-161 (2008).

• Shin HD, Kim I, Choi CB, Lee SO, Lee HW, Bae SC. Different genetic effects of interferon regulatory factor 5 (IRF5) polymorphisms on systemic lupus erythematosus in a Korean population. J. Rheumatol. 35: 2148-2151 (2008). *

• Shin HD, Kim LH, Park BL, Choi YH, Park HS, Hong SJ, Choi BW, Lee JH, Park CS. Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients. Allergy 60: 900-906 (2005). *

• Shin HD, Kim LH, Park BL, Jung JH, Kim JY, Chung IY, Kim JS, Lee JH, Chung SH, Kim YH, Park HS, Choi JH, Lee YM, Park SW, Choi BW, Hong SJ, Park CS. Association of Eotaxin gene family with asthma and serum total IgE. Hum. Mol. Genet. 12: 1279-1285 (2003). *

• Shin HD, Park BL, Cheong HS, Lee HS, Jun JB, Bae SC. DNase II polymorphisms associated with risk of renal disorder among systemic lupus erythematosus patients. J. Hum. Genet. 50: 107-111 (2005). *

• Shin HD, Park BL, Kim LH, Jung JH, Wang HJ, Kim YJ, Park HS, Hong SJ, Choi BW, Kim DJ, Park CS. Association of tumor necrosis factor polymorphisms with asthma and serum total IgE. Hum. Mol. Genet. 13: 397-403 (2004). *

• Shin HD, Park BL, Kim LH, Kim JS, Kim JW. Interleukin-10 haplotype associated with total serum IgE in atopic dermatitis patients. Allergy 60: 1146-1151 (2005). *

• Shin HD, Park BL, Kim LH, Lee HS, Kim TY, Bae SC. Common DNase I polymorphism associated with autoantibody production among systemic lupus erythematosus patients. Hum. Mol. Genet. 13: 2343-2350 (2004). *

• Shin HD, Yang SW, Kim DH, Park Y. Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility. Ann. N. Y. Acad. Sci. 1150: 76-85 (2008). *

• Shoda J, Tanaka N, Osuga T. Hepatolithiasis - epidemiology and pathogenesis update. Front. Biosci. 8: e398-e409 (2003).

• Shoenfeld Y, Selmi C, Zimlichman E, Gershwin ME. The autoimmunologist: geoepidemiology, a new center of gravity, and prime time for autoimmunity. J. Autoimmun. 31: 325-330 (2008).

• Shoenfelt J, Mitkus RA, Zeisler R, Spatz RO, Powell J, Fenton MJ, Squibb KA, Medvedev AE. Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter. J. Leukoc. Biol. 86: 303-312 (2009). *

• Shrestha S, Wang C, Aissani B, Wilson CM, Tang J, Kaslow RA. Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents. Cancer Epidemiol. Biomarkers Prev. 16: 1626-1632 (2007). *

• Shrier I, Szilagyi A, Correa JA. Impact of lactose containing foods and the genetics of lactase on diseases: an analytical review of population data. Nutr. Cancer 60: 292-300 (2008).

• Shugart YY, Silverberg MS, Duerr RH, Taylor KD, Wang MH, Zarfas K, Schumm LP, Bromfield G, Steinhart AH, Griffiths AM, Kane SV, Barmada MM, Rotter JI, Mei L, Bernstein CN, Bayless TM, Langelier D, Cohen A, Bitton A, Rioux JD, Cho JH, Brant SR. An SNP linkage scan identifies significant Crohn's disease loci on chromosomes 13q13.3 and, in Jewish families, on 1p35.2 and 3q29. Genes Immun. 9: 161-167 (2008). *

• Siahpush SH, Vaughan TL, Lampe JN, Freeman R, Lewis S, Odze RD, Blount PL, Ayub K, Rabinovitch PS, Reid BJ, Chen C. Longitudinal study of insulin-like growth factor, insulin-like growth factor binding protein-3, and their polymorphisms: risk of neoplastic progression in Barrett's esophagus. Cancer Epidemiol. Biomarkers Prev. 16: 2387-2395 (2007). *

• Sicilia B, Vicente R, Gomollon F. Epidemiology of inflammatory bowel disease: controversies in classical epidemiology. Acta Gastroenterol. Latinoam. 39: 135-145 (2009).

• Siddiqi N, Iqbal R. Maternal postpartum vitamin A supplementation programme: is there a need in Pakistan? J. Pak. Med. Assoc. 58: 265-266 (2008).

• Sie MP, Uitterlinden AG, Bos MJ, Arp PP, Breteler MM, Koudstaal PJ, Pols HA, Hofman A, van Duijn CM, Witteman JC. TGF-beta 1 polymorphisms and risk of myocardial infarction and stroke. The Rotterdam study. Stroke 37: 2667-2671 (2006).

• Sieders E, Peeters PM, TenVergert EM, de Jong KP, Porte RJ, Zwaveling JH, Bijleveld CM, Gouw AS, Slooff MJ. Graft loss after pediatric liver transplantation. Ann. Surg. 235: 125-132 (2002). *

• Siedner MJ, Christopher-Stine L, Astor BC, Gelber AC, Fine DM. Screening for proteinuria in patients with lupus: a survey of practice preferences among American rheumatologists. J. Rheumatol. 34: 973-977 (2007).

• Siegel CA, Marden SM, Persing SM, Larson RJ, Sands BE. Risk of lymphoma associated with combination anti-TNF and immunomodulator therapy for the treatment of Crohn's disease: a meta-analysis. Clin. Gastroenterol. Hepatol. 7: 874-881 (2009).

• Siegel SM, Selmi C, Dottorini L, Antelmi M, Zuin M, Lanfredini M, Gershwin ME. Late-onset autoimmunity: the paradigm of primary biliary cirrhosis - a mini-review. Gerontology 54: 193-201 (2008).

• Siegrist CA, Lewis EM, Eskola J, Evans SJ, Black SB. Human papilloma virus immunization in adolescent and young adults: a cohort study to illustrate what events might be mistaken for adverse reactions. Pediatr. Infect. Dis. J. 26: 979-984 (2007).

• Sieper J, Rudwaleit M, Khan MA, Braun J. Concepts and epidemiology of spondyloarthritis. Best Pract. Res. Clin. Rheumatol. 20: 401-417 (2006).

• Silman A, Ollier B, McDermott M. HLA: linkage with rheumatoid arthritis or seropositivity. J. Rheumatol. 15: 1189-1192 (1988).

• Silman AJ. Available therapeutic options following failure of a first anti-TNF agent. Nat. Clin. Pract. Rheumatol. 5: 115 (2009). *

• Silman AJ, Pearson JE. Epidemiology and genetics of rheumatoid arthritis. Arthritis Res. 4 Suppl. 3: S265-S272 (2002). *

• Silver MR, Messner LV. Sarcoidosis and its ocular manifestations. J. Am. Optom. Assoc. 65: 321-327 (1994).

• Simard JF, Costenbader KH. What can epidemiology tell us about systemic lupus erythematosus? Int. J. Clin. Pract. 61: 1170-1180 (2007).

• Simard JF, Costenbader KH, Hernan MA, Liang MH, Mittleman MA, Karlson EW. Early life factors and adult-onset rheumatoid arthritis. J. Rheumatol. Oct 15 [Epub ahead of print] (2009).

• Simard JF, Mittleman MA. Prevalent rheumatoid arthritis and diabetes among NHANES III participants aged 60 and older. J. Rheumatol. 34: 469-473 (2007).

• Simon J, Kotloff K. New and candidate vaccines for gastrointestinal infections. Curr. Opin. Gastroenterol. 26: 12-16 (2010).

• Simon K, Yang X, Munger K, Ascherio A. Variation in the Epstein-Barr virus receptor, CR2, and risk of multiple sclerosis. Mult. Scler. 13: 947-948 (2007). *

• Simpson M, Mojibian M, Barriga K, Scott F, Fasano A, Rewers M, Norris J. An exploration of Glo-3A antibody levels in children at increased risk for type 1 diabetes mellitus. Pediatr. Diabetes 10: 563-572 (2009).

• Singh H, Demers AA, Nugent Z, Mahmud SM, Kliewer EV, Bernstein CN. Risk of cervical abnormalities in women with inflammatory bowel disease: a population-based, nested, case-control study. Gastroenterology 136: 451-458 (2009). *

• Singh KK, Kulawiec M. Mitochondrial DNA polymorphism and risk of cancer. Methods Mol. Biol. 471: 291-303 (2009). *

• Singh P, Patel T. Advances in the diagnosis, evaluation and management of cholangiocarcinoma. Curr. Opin. Gastroenterol. 22: 294-299 (2006).

• Sinha R, Anderson DE, McDonald SS, Greenwald P. Cancer risk and diet in India. J. Postgrad. Med. 49: 222-228 (2003). *

• Sinha S, Mishra SK, Sharma S, Patibandla PK, Mallick PK, Sharma SK, Mohanty S, Pati SS, Mishra SK, Ramteke BK, Bhatt RM, Joshi H, Dash AP, Ahuja RC, Awasthi S, Consortium IG, Venkatesh V, Habib S. Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar. J. 7: 13 (2008).

• Sivagnanam P, Koutsoumpas A, Forbes A. Respiratory symptoms in patients with inflammatory bowel disease and the impact of dietary salicylates. Dig. Liver Dis. 39: 232-239 (2007).

• Slattery ML. Vitamin D receptor gene (VDR) associations with cancer. Nutr. Rev. 65: S102-S104 (2007). *

• Slattery ML, Curtin K, Giuliano AR, Sweeney C, Baumgartner R, Edwards S, Wolff RK, Baumgartner KB, Byers T. Active and passive smoking, IL6, ESR1, and breast cancer risk. Breast Cancer Res. Treat. 109: 101-111 (2008). *

• Sleiman PM, Flory J, Imielinski M, Bradfield JP, Annaiah K, Willis-Owen SA, Wang K, Rafaels NM, Michel S, Bonnelykke K, Zhang H, Kim CE, Frackelton EC, Glessner JT, Hou C, Otieno FG, Santa E, Thomas K, Smith RM, Glaberson WR, Garris M, Chiavacci RM, et al. Variants of DENND1B associated with asthma in children. N. Engl. J. Med. 362: 36-44 (2010). *

• Slyk MP, Frazee LA. Nicotine: does it have a role in the treatment of ulcerative colitis? Am. J. Ther. 4: 141-148 (1997).

• Smedby KE, Akerman M, Hildebrand H, Glimelius B, Ekbom A, Askling J. Malignant lymphomas in coeliac disease: evidence of increased risks for lymphoma types other than enteropathy-type T cell lymphoma. Gut 54: 54-59 (2005). *

• Smedby KE, Baecklund E, Askling J. Malignant lymphomas in autoimmunity and inflammation: a review of risks, risk factors, and lymphoma characteristics. Cancer Epidemiol. Biomarkers Prev. 15: 2069-2077 (2006). *

• Smedby KE, Hjalgrim H, Askling J, Chang ET, Gregersen H, Porwit-MacDonald A, Sundstrom C, Akerman M, Melbye M, Glimelius B, Adami HO. Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype. J. Natl. Cancer Inst. 98: 51-60 (2006). *

• Smeeth L, Douglas I, Hall AJ, Hubbard R, Evans S. Effect of statins on a wide range of health outcomes: a cohort study validated by comparison with randomized trials. Br. J. Clin. Pharmacol. 67: 99-109 (2009). *

• Smit LA, Heederik D, Doekes G, Krop EJ, Rijkers GT, Wouters IM. Ex vivo cytokine release reflects sensitivity to occupational endotoxin exposure. Eur. Respir. J. 34: 795-802 (2009).

• Smit LA, Siroux V, Bouzigon E, Oryszczyn MP, Lathrop M, Demenais F, Kauffmann F. CD14 and Toll-like receptor gene polymorphisms, country living, and asthma in adults. Am. J. Respir. Crit. Care Med. 179: 363-368 (2009). *

• Smith I, Nathan C, Peavy HH; NHLBI Working Group. Progress and new directions in genetics of tuberculosis: an NHLBI working group report. Am. J. Respir. Crit. Care Med. 172: 1491-1496 (2005). *

• Smith JA, Arnett DK, Kelly RJ, Ordovas JM, Sun YV, Hopkins PN, Hixson JE, Straka RJ, Peacock JM, Kardia SL. The genetic architecture of fasting plasma triglyceride response to fenofibrate treatment. Eur. J. Hum. Genet. 16: 603-613 (2008). *

• Smith N, Weymann A, Tausk FA, Gelfand JM. Complementary and alternative medicine for psoriasis: a qualitative review of the clinical trial literature. J. Am. Acad. Dermatol. 61: 841-856 (2009).

• Smith RL, Eyre S, Warren RB, Young HS, Griffiths CE, Worthington J. No association between polymorphisms in the interleukin-15 gene and early-onset psoriasis in a UK cohort suggests heterogeneity for this susceptibility locus identified in Chinese psoriasis patients. J. Invest. Dermatol. 128: 2904-2905 (2008). *

• Smith RL, Warren RB, Eyre S, Ho P, Ke X, Young HS, Griffiths CE, Worthington J. Polymorphisms in the IL-12beta and IL-23R genes are associated with psoriasis of early onset in a UK cohort. J. Invest. Dermatol. 128: 1325-1327 (2008). *

• Smith RL, Warren RB, Eyre S, Ke X, Young HS, Allen M, Strachan D, McArdle W, Gittins MP, Barker JN, Griffiths CE, Worthington J. Polymorphisms in the PTPN22 region are associated with psoriasis of early onset. Br. J. Dermatol. 158: 962-968 (2008). *

• Smith RL, Warren RB, Griffiths CE, Worthington J. Genetic susceptibility to psoriasis: an emerging picture. Genome Med. 1: 72 (2009). *

• So A. Developments in the scientific and clinical understanding of gout. Arthritis Res. Ther. 10: 221 (2008). *

• Soetikno RM, Kahng LS, Ono A, Fujii T. Flat and depressed colorectal neoplasms. Curr. Opin. Gastroenterol. 19: 69-75 (2003).

• Sogaard KK, Cronin-Fenton DP, Pedersen L, Sorensen HT, Lash TL. Survival in Danish patients with breast cancer and inflammatory bowel disease: a nationwide cohort study. Inflamm. Bowel Dis. 14: 519-525 (2008). *

• Sogaard KK, Horvath-Puho E, Gronbaek H, Jepsen P, Vilstrup H, Sorensen HT. Risk of venous thromboembolism in patients with liver disease: a nationwide population-based case-control study. Am. J. Gastroenterol. 104: 96-101 (2009). *

• Sohns M, Rosenberger A, Bickeboller H. Integration of a priori gene set information into genome-wide association studies. BMC Proc. 3 Suppl. 7: S95 (2009). *

• Solaymani-Dodaran M, Aithal GP, Card T, West J. Risk of cardiovascular and cerebrovascular events in primary biliary cirrhosis: a population-based cohort study. Am. J. Gastroenterol. 103: 2784-2788 (2008). *

• Solaymani-Dodaran M, Card TR, Aithal GP, West J. Fracture risk in people with primary biliary cirrhosis: a population based cohort study. Gastroenterology 131: 1752-1757 (2006). *

• Solaymani-Dodaran M, West J, Logan RF. Long-term mortality in people with celiac disease diagnosed in childhood compared with adulthood: a population-based cohort study. Am. J. Gastroenterol. 102: 864-870 (2007). *

• Solomon DH, Cadarette SM, Choudhry NK, Canning C, Levin R, Sturmer T. A cohort study of thiazolidinediones and fractures in older adults with diabetes. J. Clin. Endocrinol. Metab. 94: 2792-2798 (2009). *

• Solomon MJ, Schnitzler M. Cancer and inflammatory bowel disease: bias, epidemiology, surveillance, and treatment. World J. Surg. 22: 352-358 (1998). *

• Somers EC, Thomas SL, Smeeth L, Hall AJ. Autoimmune diseases co-occurring within individuals and within families: a systematic review. Epidemiology 17: 202-217 (2006).

• Song F, Ji P, Zheng H, Song F, Wang Y, Hao X, Wei Q, Zhang W, Chen K. Definition of a functional single nucleotide polymorphism in the cell migration inhibitory gene MIIP that affects the risk of breast cancer. Cancer Res. Jan 26 [Epub ahead of print] (2010). *

• Song Y, Cook NR, Albert CM, Van Denburgh M, Manson JE. Effect of homocysteine-lowering treatment with folic acid and B vitamins on risk of type 2 diabetes mellitus in women: a randomized controlled trial. Diabetes 58: 1921-1928 (2009). *

• Song Y, Miyaki K, Araki J, Zhang L, Omae K, Muramatsu M. The interaction between the interleukin 6 receptor gene genotype and dietary energy intake on abdominal obesity in Japanese men. Metabolism 56: 925-930 (2007).

• Sonnenberg A. Similar geographic variations in mortality from peptic ulcer and inflammatory bowel disease. Inflamm. Bowel Dis. 13: 763-768 (2007). *

• Sontag MK, Quittner AL, Modi AC, Koenig JM, Giles D, Oermann CM, Konstan MW, Castile R, Accurso FJ; On behalf of the Investigators and Coordinators of the Airway Secretion Clearance Trial. Lessons learned from a randomized trial of airway secretion clearance techniques in cystic fibrosis. Pediatr. Pulmonol. Feb 9 [Epub ahead of print] (2010). *

• Sontag MK, Wright D, Beebe J, Accurso FJ, Sagel SD. A new cystic fibrosis newborn screening algorithm: IRT/IRT1 upward arrow/DNA. J. Pediatr. 155: 618-622 (2009). *

• Sontrop J, Avison WR, Evers SE, Speechley KN, Campbell MK. Depressive symptoms during pregnancy in relation to fish consumption and intake of n-3 polyunsaturated fatty acids. Paediatr. Perinat. Epidemiol. 22: 389-399 (2008).

• Sontrop J, Campbell MK. Omega-3 polyunsaturated fatty acids and depression: a review of the evidence and a methodological critique. Prev. Med. 42: 4-13 (2006). *

• Sood A, Midha V. Epidemiology of inflammatory bowel disease in Asia. Indian J. Gastroenterol. 26: 285-289 (2007). *

• Sood BG, Madan A, Saha S, Schendel D, Thorsen P, Skogstrand K, Hougaard D, Shankaran S, Carlo W; On behalf of the NICHD Neonatal Research Network. Perinatal systemic inflammatory response syndrome and retinopathy of prematurity. Pediatr. Res. Dec 21 [Epub ahead of print] (2009).

• Sood S, Gow PJ, Christie JM, Angus PW. Epidemiology of primary biliary cirrhosis in Victoria, Australia: high prevalence in migrant populations. Gastroenterology 127: 470-475 (2004). *

• Soranzo N, Spector TD, Mangino M, Kuhnel B, Rendon A, Teumer A, Willenborg C, Wright B, Chen L, Li M, Salo P, Voight BF, Burns P, Laskowski RA, Xue Y, Menzel S, Altshuler D, Bradley JR, Bumpstead S, Burnett MS, Devaney J, Doring A, Elosua R, et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium. Nat. Genet. 41: 1182-1190 (2009). *

• Sorensen HT, Lash TL, Rothman KJ. Beyond randomized controlled trials: a critical comparison of trials with nonrandomized studies. Hepatology 44: 1075-1082 (2006). *

• Sorensen HT, Thulstrup AM, Blomqvist P, Norgaard B, Fonager K, Ekbom A. Risk of primary biliary liver cirrhosis in patients with coeliac disease: Danish and Swedish cohort data. Gut 44: 736-738 (1999). *

• Soria J, Garagorri JM, Rodriguez M, Rodriguez G, Larrad L, Elizalde M. Epidemiology and genetic risk of type 1 diabetes among children in Aragon community, Spain. Diabetes Res. Clin. Pract. 79: 112-116 (2008).

• Spehlmann ME, Begun AZ, Burghardt J, Lepage P, Raedler A, Schreiber S. Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study. Inflamm. Bowel Dis. 14: 968-976 (2008). *

• Spritz RA. The genetics of generalized vitiligo and associated autoimmune diseases. Pigment Cell Res. 20: 271-278 (2007).

• Spritz RA. The genetics of generalized vitiligo and associated autoimmune diseases. J. Dermatol. Sci. 41: 3-10 (2006).

• Spritz RA. The genetics of generalized vitiligo. Curr. Dir. Autoimmun. 10: 244-257 (2008).

• Srivatanakul P, Sriplung H, Deerasamee S. Epidemiology of liver cancer: an overview. Asian Pacific J. Cancer Prev. 5: 118-125 (2004). *

• Staples JA, Ponsonby AL, Lim LL, McMichael AJ. Ecologic analysis of some immune-related disorders, including type 1 diabetes, in Australia: latitude, regional ultraviolet radiation, and disease prevalence. Environ. Health Perspect. 111: 518-523 (2003). *

• Stark JR, Wiklund F, Gronberg H, Schumacher F, Sinnott JA, Stampfer MJ, Mucci LA, Kraft P. Toll-like receptor signaling pathway variants and prostate cancer mortality. Cancer Epidemiol. Biomarkers Prev. 18: 1859-1863 (2009). *

• Steed H, Walsh S, Reynolds N. A brief report of the epidemiology of obesity in the inflammatory bowel disease population of Tayside, Scotland. Obes. Facts 2: 370-372 (2009).

• Steele IL, Levy C, Lindor KD. Primary sclerosing cholangitis - approach to diagnosis. MedGenMed. 9: 20 (2007). *

• Steevens J, Schouten LJ, Goldbohm RA, van den Brandt PA. Alcohol consumption, cigarette smoking and risk of subtypes of oesophageal and gastric cancer: a prospective cohort study. Gut 59: 39-48 (2010).

• Steffen LM, Folsom AR, Cushman M, Jacobs DR Jr, Rosamond WD. Greater fish, fruit, and vegetable intakes are related to lower incidence of venous thromboembolism. The longitudinal investigation of thromboembolism etiology. Circulation 115: 188-195 (2007). *

• Stein CM, Schick JH, Gerry Taylor H, Shriberg LD, Millard C, Kundtz-Kluge A, Russo K, Minich N, Hansen A, Freebairn LA, Elston RC, Lewis BA, Iyengar SK. Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am. J. Hum. Genet. 74: 283-297 (2004). *

• Stein JM, Hartmann F, Cordes HJ, Dignass AU. Pathophysiological-based diagnosis and therapy of iron-deficient anaemia in inflammatory bowel disease. Z. Gastroenterol. 47: 228-236 (2009).

• Stein WD, Bates SE, Fojo T. Intractable cancers: the many faces of multidrug resistance and the many targets it presents for therapeutic attack. Curr. Drug Targets 5: 333-346 (2004).

• Stelzmueller I, Berger N, Wiesmayr S, Eller M, Tabarelli W, Fille M, Margreiter R, Bonatti H. Group milleri streptococci: significant pathogens in solid organ recipients. Transpl. Int. 20: 51-56 (2007). *

• Stene LC, Thorsby PM, Berg JP, Ronningen KS, Joner G; the Norwegian Childhood Diabetes Study Group. Peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism, cod liver oil and risk of type 1 diabetes. Pediatr. Diabetes 9: 40-45 (2008). *

• Steptoe A, Hamer M, Chida Y. The effects of acute psychological stress on circulating inflammatory factors in humans: a review and meta-analysis. Brain Behav. Immun. 21: 901-912 (2007).

• Stern JN, Keskin DB. Strategies for the identification of loci responsible for the pathogenesis of multiple sclerosis. Cell. Mol. Biol. Lett. 13: 656-666 (2008). *

• Sterzenbach T, Bartonickova L, Behrens W, Brenneke B, Schulze J, Kops F, Chin EY, Katzowitsch E, Schauer DB, Fox JG, Suerbaum S, Josenhans C. Role of the Helicobacter hepaticus flagellar sigma factor FliA in gene regulation and murine colonization. J. Bacteriol. 190: 6398-6408 (2008). *

• Sterzenbach T, Lee SK, Brenneke B, von Goetz F, Schauer DB, Fox JG, Suerbaum S, Josenhans C. Inhibitory effect of enterohepatic Helicobacter hepaticus on innate immune responses of mouse intestinal epithelial cells. Infect. Immun. 75: 2717-2728 (2007). *

• Stevens A, Ray DW, Zeggini E, John S, Richards HL, Griffiths CE, Donn R. Glucocorticoid sensitivity is determined by a specific glucocorticoid receptor haplotype. J. Clin. Endocrinol. Metab. 89: 892-897 (2004). *

• Stevens VL, Hsing AW, Talbot JT, Zheng SL, Sun J, Chen J, Thun MJ, Xu J, Calle EE, Rodriguez C. Genetic variation in the Toll-like receptor gene cluster (TLR10-TLR1-TLR6) and prostate cancer risk. Int. J. Cancer 123: 2644-2650 (2008). *

• Stevenson K, Alvarez J, Bakker D, Biet F, de Juan L, Denham S, Dimareli Z, Dohmann K, Gerlach GF, Heron I, Kopecna M, May L, Pavlik I, Sharp JM, Thibault V, Willemsen P, Zadoks R, Greig A. Occurrence of Mycobacterium avium subspecies paratuberculosis across host species and European countries with evidence for transmission between wildlife and domestic ruminants. BMC Microbiol. 9: 212 (2009). *

• Stoll M, Corneliussen B, Costello CM, Waetzig GH, Mellgard B, Koch WA, Rosenstiel P, Albrecht M, Croucher PJ, Seegert D, Nikolaus S, Hampe J, Lengauer T, Pierrou S, Foelsch UR, Mathew CG, Lagerstrom-Fermer M, Schreiber S. Genetic variation in DLG5 is associated with inflammatory bowel disease. Nat. Genet. 36: 476-480 (2004). *

• Stolzenberg-Solomon RZ. Vitamin D and pancreatic cancer. Ann. Epidemiol. 19: 89-95 (2009).

• Stone A, Quittell L, Zhou J, Alba L, Bhat M, Decelie-Germana J, Rajan S, Bonitz L, Welter JJ, Dozor AJ, Gherson I, Lowy FD, Saiman L. Staphylococcus aureus nasal colonization among pediatric CF patients and their household contacts. Pediatr. Infect. Dis. J. Aug 14 [Epub ahead of print] (2009).

• Stone A, Quittell L, Zhou J, Alba L, Bhat M, DeCelie-Germana J, Rajan S, Bonitz L, Welter JJ, Dozor AJ, Gherson I, Lowy FD, Saiman L. Staphylococcus aureus nasal colonization among pediatric cystic fibrosis patients and their household contacts. Pediatr. Infect. Dis. J. 28: 895-899 (2009).

• Stone J, Gurrin LC, Hayes VM, Southey MC, Hopper JL, Byrnes GB. Sibship analysis of associations between SNP haplotypes and a continuous trait with application to mammographic density. Genet. Epidemiol. Nov 13 [Epub ahead of print] (2009).

• Stonehouse W, Kruger A, Smuts CM, Loots DT, Wentzel-Viljoen E, Vorster HH. Plasma polyunsaturated fatty acids and liver enzymes in HIV-infected subjects: the Prospective Urban and Rural Epidemiology (PURE) study. Am. J. Clin. Nutr. Jan 13 [Epub ahead of print] (2010). *

• Strangfeld A, Listing J. Bacterial and opportunistic infections during anti-TNF therapy. Best Pract. Res. Clin. Rheumatol. 20: 1181-1195 (2006).

• Strausbaugh SD, Davis PB. Cystic fibrosis: a review of epidemiology and pathobiology. Clin. Chest Med. 28: 279-288 (2007).

• Stroffolini T, Sagnelli E, Almasio P, Ferrigno L, Crax`i A, Melea A, on behalf of the Italian Hospitals Collaborating Groups. Characteristics of liver cirrhosis in Italy: results from a multicenter national study. Dig. Liver Dis. 36: 56-60 (2004). *

• Stroffolini T, Sagnelli E, Mele A, Craxi A, Almasio P; Italian Hospitals Collaborating Group. The aetiology of chronic hepatitis in Italy: results from a multicentre national study. Dig. Liver Dis. 36: 829-833 (2004).

• Strom SS, Baldwin BJ, Sigurdson AJ, Schusterman MA. Cosmetic saline breast implants: a survey of satisfaction, breast-feeding experience, cancer screening, and health. Plast. Reconstr. Surg. 100: 1553-1557 (1997).

• Studer M, Briel M, Leimenstoll B, Glass TR, Bucher HC. Effect of different antilipidemic agents and diets on mortality: a systematic review. Arch. Intern. Med. 165: 725-730 (2005). *

• Su H, Wang BL, Zhang XJ, Hao JH, Xiao Q, Ye DQ. Disequilibrium linkage between the polymorphism in exons 2, 3 and 4 of the MICA gene and HLA-B antigen of patient with ankylosing spondylitis. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 23: 446-448 (2006).

• Su H, Ye DQ, Wang BL, Fang XH, Chen J, Wang Q, Li WX, Zhang N. Transforming growth factor-beta1-induced CD4+CD25+ regulatory T cells in vitro reverse and prevent a murine lupus-like syndrome of chronic graft-versus-host disease. Br. J. Dermatol. 158: 1197-1209 (2008). *

• Su S, Zhao J, Bremner JD, Miller AH, Tang W, Bouzyk M, Snieder H, Novik O, Afzal N, Goldberg J, Vaccarino V. Serotonin transporter gene, depressive symptoms, and interleukin-6. Circ. Cardiovasc. Genet. 2: 614-620 (2009).

• Sudfeld CR, Dasenbrook EC, Merz WG, Carroll KC, Boyle MP. Prevalence and risk factors for recovery of filamentous fungi in individuals with cystic fibrosis. J. Cyst. Fibros. Dec 30 [Epub ahead of print] (2009).

• Suerbaum S. Microbiome analysis in the esophagus. Gastroenterology 137: 419-421 (2009). *

• Suite M. The epidemiology of psoriasis in a dermatology clinic in a general hospital in Port-of-Spain, Trinidad and Tobago, West Indies. West Indian Med. J. 55: 399-402 (2006).

• Suleymanoglu E. Molecular phylogenetics and functional evolution of major RNA recognition domains of recently cloned and characterized autoimmune RNA-binding particle. Genomics Proteomics Bioinformatics 1: 310-320 (2003).

• Sulkowski M. Hepatocellular carcinoma in HIV-infected patients comes of age: the convergence of epidemiology and treatment effectiveness. J. Hepatol. 50: 655-658 (2009).

• Sullivan PF, Kuo PH, Webb BT, Neale MC, Vittum J, Furberg H, Walsh D, Patterson DG, Riley B, Prescott CA, Kendler KS. Genomewide linkage survey of nicotine dependence phenotypes. Drug Alcohol Depend. 93: 210-216 (2008).

• Sun F, Chen Y, Xiang Y, Zhan S. Drug-metabolising enzyme polymorphisms and predisposition to anti-tuberculosis drug-induced liver injury: a meta-analysis. Int. J. Tuberc. Lung Dis. 12: 994-1002 (2008).

• Sun T, Hu Z, Shen H, Lin D. Genetic polymorphisms in cytotoxic T-lymphocyte antigen 4 and cancer: the dialectical nature of subtle human immune dysregulation. Cancer Res. 69: 6011-6014 (2009). *

• Sun YV, Cai Z, Desai K, Lawrance R, Leff R, Jawaid A, Kardia SL, Yang H. Classification of rheumatoid arthritis status with candidate gene and genome-wide single-nucleotide polymorphisms using random forests. BMC Proc. 1 Suppl. 1: S62 (2007). *

• Sun YV, Kardia SL. Imputing missing genotypic data of single-nucleotide polymorphisms using neural networks. Eur. J. Hum. Genet. 16: 487-495 (2008).

• Sun YV, Shedden KA, Zhu J, Choi NH, Kardia SL. Identification of correlated genetic variants jointly associated with rheumatoid arthritis using ridge regression. BMC Proc. 3 Suppl. 7: S67 (2009). *

• Sung FY, Jung CM, Wu CF, Lin CL, Liu CJ, Liaw YF, Tsai KS, Yu MW. Hepatitis B virus core variants modify natural course of viral infection and hepatocellular carcinoma progression. Gastroenterology 137: 1687-1697 (2009). *

• Surawicz CM. Treatment of recurrent Clostridium difficile-associated disease. Nat. Clin. Pract. Gastroenterol. Hepatol. 1: 32-38 (2004). *

• Suresh S, Demirci FY, Jacobs E, Kao AH, Rhew EY, Sanghera DK, Selzer F, Sutton-Tyrrell K, McPherson D, Bontempo FA, Kammerer CM, Ramsey-Goldman R, Manzi S, Kamboh MI. Apolipoprotein H promoter polymorphisms in relation to lupus and lupus-related phenotypes. J. Rheumatol. 36: 315-322 (2009).

• Surowiec D, Kuyumjian AG, Wynd MA, Cicogna CE. Past, present, and future therapies for Clostridium difficile-associated disease. Ann. Pharmacother. 40: 2155-2163 (2006).

• Suzuki T, Matsuo K, Hirose K, Hiraki A, Kawase T, Watanabe M, Yamashita T, Iwata H, Tajima K. One-carbon metabolism-related gene polymorphisms and risk of breast cancer. Carcinogenesis 29: 356-362 (2008). *

• Suzuki T, Matsuo K, Sawaki A, Mizuno N, Hiraki A, Kawase T, Watanabe M, Nakamura T, Yamao K, Tajima K, Tanaka H. Alcohol drinking and one-carbon metabolism-related gene polymorphisms on pancreatic cancer risk. Cancer Epidemiol. Biomarkers Prev. 17: 2742-2747 (2008). *

• Svejgaard A. The immunogenetics of multiple sclerosis. Immunogenetics 60: 275-286 (2008). *

• Swennen EL, Coolen EJ, Arts IC, Bast A, Dagnelie PC. Time-dependent effects of ATP and its degradation products on inflammatory markers in human blood ex vivo. Immunobiology 213: 389-397 (2008).

• Sykora J, Subrt I, Didek P, Siala K, Schwarz J, Machalova V, Varvarovska J, Pazdiora P, Pozler O, Stozicky F. Cytokine tumor necrosis factor-alpha promoter gene polymorphism at position -308 G-->A and pediatric inflammatory bowel disease: implications in ulcerative colitis and Crohn's disease. J. Pediatr. Gastroenterol. Nutr. 42: 479-487 (2006). *

• Symmons DP. Epidemiology and rheumatology: how can epidemiologists affect treatment strategies? Nat. Clin. Pract. Rheumatol. 4: 1 (2008). *

• Symmons DP. Classification criteria for rheumatoid arthritis - time to abandon rheumatoid factor? Rheumatology (Oxford) 46: 725-726 (2007). *

• Symmons DP. Looking back: rheumatoid arthritis - aetiology, occurrence and mortality. Rheumatology (Oxford) 44 Suppl. 4: iv14-iv17 (2005). *

• Symmons DP, Silman AJ. The world of biologics. Lupus 15: 122-126 (2006).

• Szabo E, Boehm G, Beermann C, Weyermann M, Brenner H, Rothenbacher D, Decsi T. Fatty acid profile comparisons in human milk sampled from the same mothers at the sixth week and the sixth month of lactation. J. Pediatr. Gastroenterol. Nutr. Jan 27 [Epub ahead of print] (2010).

• Takada T, Kawarada Y, Nimura Y, Yoshida M, Mayumi T, Sekimoto M, Miura F, Wada K, Hirota M, Yamashita Y, Nagino M, Tsuyuguchi T, Tanaka A, Kimura Y, Yasuda H, Hirata K, Pitt HA, Strasberg SM, Gadacz TR, Bornman PC, Gouma DJ, Belli G, Liau KH. Background: Tokyo Guidelines for the management of acute cholangitis and cholecystitis. J. Hepatobiliary Pancreat. Surg. 14: 1-10 (2007).

• Takahashi Y, Masuda H, Ishii Y, Nishida Y, Kobayashi M, Asai S. Decreased expression of thioredoxin interacting protein mRNA in inflamed colonic mucosa in patients with ulcerative colitis. Oncol. Rep. 18: 531-535 (2007). *

• Takikawa Y, Suzuki K. Clinical epidemiology of fulminant hepatitis in Japan. Hepatol. Res. 38 (s1: The 6 Japan Society of Hepatology Single Topic Conference: Liver Failure: Recent Progress and Pathogenesis to Management. 28-29 September 2007, Iwate, Japan): S14-S18 (2008).

• Talwalkar JA, Kim WR. Medical and economic impact of autoimmune hepatitis. Clin. Liver Dis. 6: 361-379 (2002).

• Tamboli CP. How do genetics help an understanding of IBD epidemiology? Inflamm. Bowel Dis. 14 Suppl. 2: S29-S30 (2008). *

• Tamez S, Norizoe C, Ochiai K, Takahashi D, Shimojima A, Tsutsumi Y, Yanaihara N, Tanaka T, Okamoto A, Urashima M. Vitamin D receptor polymorphisms and prognosis of patients with epithelial ovarian cancer. Br. J. Cancer 101: 1957-1960 (2009). *

• Tan XL, Nieters A, Kropp S, Hoffmeister M, Brenner H, Chang-Claude J. The association of cyclin D1 G870A and E-cadherin C-160A polymorphisms with the risk of colorectal cancer in a case control study and meta-analysis. Int. J. Cancer 122: 2573-2580 (2008). *

• Tang X, Pan F, Xia G, Liao F, Ge R, Mei Y, Ye D, Xu S, Xu J. A single-nucleotide polymorphism marker within the FCRL5 gene and HLA-B27 positive Han Chinese ankylosing spondylitis patients. Tissue Antigens 74: 314-316 (2009). *

• Taori SK, Hall V, Poxton I. The influence of antibiotics on the changing epidemiology of Clostridium difficile. J. Med. Microbiol. Nov 26 [Epub ahead of print] (2009). *

• Tatemichi M, Iwasaki M, Sasazuki S, Tsugane S. Association between polymorphisms in glutathione S-transferase Mu3 and IgG titer levels in serum against Helicobacter pylori. J. Hum. Genet. 54: 557-563 (2009).

• Tay J, Tinmouth A, Fergusson D, Huebsch L, Allan DS. Systematic review of controlled clinical trials on the use of ursodeoxycholic acid for the prevention of hepatic veno-occlusive disease in hematopoietic stem cell transplantation. Biol. Blood Marrow Transplant. 13: 206-217 (2007).

• Taylor WJ. Epidemiology of psoriatic arthritis. Curr. Opin. Rheumatol. 14: 98-103 (2002).

• Tchatchou S, Riedel A, Lyer S, Schmutzhard J, Strobel-Freidekind O, Gronert-Sum S, Mietag C, D'Amato M, Schlehe B, Hemminki K, Sutter C, Ditsch N, Blackburn A, Hill LZ, Jerry DJ, Bugert P, Weber BH, Niederacher D, Arnold N, Varon-Mateeva R, et al. Identification of a DMBT1 polymorphism associated with increased breast cancer risk and decreased promoter activity. Hum. Mutat. 31: 60-66 (2010).

• Tenembaum S, Chitnis T, Ness J, Hahn JS. Acute disseminated encephalomyelitis. Neurology 68: S23-S36 (2007).

• Terry P, Bergkvist L, Holmberg L, Wolk A. Coffee consumption and risk of colorectal cancer in a population based prospective cohort of Swedish women. Gut 49: 87-90 (2001). *

• Terry P, Bergkvist L, Holmberg L, Wolk A. No association between fat and fatty acids intake and risk of colorectal cancer. Cancer Epidemiol. Biomarkers Prev. 10: 913-914 (2001). *

• Terry PD, Goodman M. Is the association between cigarette smoking and breast cancer modified by genotype? A review of epidemiologic studies and meta-analysis. Cancer Epidemiol. Biomarkers Prev. 15: 602-611 (2006). *

• Terry PD, Villinger F, Bubenik GA, Sitaraman SV. Melatonin and ulcerative colitis: evidence, biological mechanisms, and future research. Inflamm. Bowel Dis. 15: 134-140 (2009). *

• Terry SF, Boyd CD. Researching the biology of PXE: partnering in the process. Am. J. Med. Genet. 106: 177-184 (2001).

• Terzic D, Dupanovic B, Mugosa B, Draskovic N, Svirtlih N. Acute hepatitis E in Montenegro: epidemiology, clinical and laboratory features. Ann. Hepatol. 8: 203-206 (2009).

• Testa A, Benedetto FA, Spoto B, Pisano A, Tripepi G, Mallamaci F, Malatino LS, Zoccali C. The E-selectin gene polymorphism and carotid atherosclerosis in end-stage renal disease. Nephrol. Dial. Transplant. 21: 1921-1926 (2006). *

• Thabane M, Simunovic M, Akhtar-Danesh N, Marshall JK. Development and validation of a risk score for post-infectious irritable bowel syndrome. Am. J. Gastroenterol. 104: 2267-2274 (2009). *

• Thaler K, Chandiramani DV, Hansen RA, Gartlehner G. Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug Effectiveness Review Project. Biologics 3: 485-498 (2009). *

• The Breast Cancer Linkage Consortium. Cancer risks in BRCA2 mutation carriers. J. Natl. Cancer Inst. 91: 1310-1316 (1999). *

• The Genetic Factors for Osteoporosis (GEFOS) Consortium, Rivadeneira F, Styrkarsdottir U, Estrada K, Halldorsson BV, Hsu YH, Richards JB, Zillikens MC, Kavvoura FK, Amin N, Aulchenko YS, Cupples LA, Deloukas P, Demissie S, Grundberg E, Hofman A, et al. Twenty bone-mineral-density loci identified by large-scale meta-analysis of genome-wide association studies. Nat. Genet. 41: 1199-1206 (2009). *

• Thellenberg-Karlsson C, Lindstrom S, Malmer B, Wiklund F, Augustsson-Balter K, Adami HO, Stattin P, Nilsson M, Dahlman-Wright K, Gustafsson JA, Gronberg H. Estrogen receptor beta polymorphism is associated with prostate cancer risk. Clin. Cancer Res. 12: 1936-1941 (2006). *

• Thia KT, Loftus EV Jr, Sandborn WJ, Yang SK. An update on the epidemiology of inflammatory bowel disease in Asia. Am. J. Gastroenterol. 103: 3167-3182 (2008). *

• Thomas G, Jacobs KB, Kraft P, Yeager M, Wacholder S, Cox DG, Hankinson SE, Hutchinson A, Wang Z, Yu K, Chatterjee N, Garcia-Closas M, Gonzalez-Bosquet J, Prokunina-Olsson L, Orr N, Willett WC, Colditz GA, Ziegler RG, Berg CD, Buys SS, McCarty CA, et al. A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1). Nat. Genet. 41: 579-584 (2009). *

• Thomas G, Jacobs KB, Yeager M, Kraft P, Wacholder S, Orr N, Yu K, Chatterjee N, Welch R, Hutchinson A, Crenshaw A, Cancel-Tassin G, Staats BJ, Wang Z, Gonzalez-Bosquet J, Fang J, Deng X, Berndt SI, Calle EE, Feigelson HS, Thun MJ, Rodriguez C, et al. Multiple loci identified in a genome-wide association study of prostate cancer. Nat. Genet. 40: 310-315 (2008). *

• Thomas HJ, Wotton CJ, Yeates D, Ahmad T, Jewell DP, Goldacre MJ. Pneumococcal infection in patients with coeliac disease. Eur. J. Gastroenterol. Hepatol. 20: 624-628 (2008).

• Thompson CL, Baechle D, Lu Q, Mathew G, Song Y, Iyengar SK, Gray-McGuire C, Goddard KA. Effect of genotyping error in model-free linkage analysis using microsatellite or single-nucleotide polymorphism marker maps. BMC Genet. 6 Suppl. 1: S153 (2005). *

• Thompson D, Witte JS, Slattery M, Goldgar D. Increased power for case-control studies of single nucleotide polymorphisms through incorporation of family history and genetic constraints. Genet. Epidemiol. 27: 215-224 (2004). *

• Thomson W, Barton A, Ke X, Eyre S, Hinks A, Bowes J, Donn R, Symmons D, Hider S, Bruce IN; Wellcome Trust Case Control Consortium, Wilson AG, Marinou I, Morgan A, Emery P; YEAR Consortium, Carter A, Steer S, Hocking L, Reid DM, Wordsworth P, et al. Rheumatoid arthritis association at 6q23. Nat. Genet. 39: 1431-1433 (2007). *

• Thomson W, Harrison B, Ollier B, Wiles N, Payton T, Barrett J, Symmons D, Silman A. Quantifying the exact role of HLA-DRB1 alleles in susceptibility to inflammatory polyarthritis: results from a large, population-based study. Arthritis Rheum. 42: 757-762 (1999). *

• Thornblad TA, Elliott KS, Jowett J, Visscher PM. Prioritization of positional candidate genes using multiple web-based software tools. Twin Res. Hum. Genet. 10: 861-870 (2007).

• Thun MJ, Henley SJ, Gansler T. Inflammation and cancer: an epidemiological perspective. Novartis Found. Symp. 256: 6-21 (2004).

• Tiemeier H, van Tuijl HR, Hofman A, Kiliaan AJ, Breteler MM. Plasma fatty acid composition and depression are associated in the elderly: the Rotterdam Study. Am. J. Clin. Nutr. 78: 40-46 (2003). *

• Tierney BC, Martin SW, Franzke LH, Marano N, Reissman DB, Louchart RD, Goff JA, Rosenstein NE, Sever JL, McNeil MM; Centers for Disease Control and Prevention's Anthrax Vaccine and Antimicrobial Availability Program. Serious adverse events among participants in the Centers for Disease Control and Prevention's Anthrax Vaccine and Antimicrobial Availability Program for persons at risk for bioterrorism-related inhalational anthrax. Clin. Infect. Dis. 37: 905-911 (2003). *

• Timmer A. Environmental epidemiology. Falk Symposium 140. Inflammatory Bowel Disease: Translation from Basic Research to Clinical Practice. Dubrovnik (Croatia). p. 47. May 7-8 (2004). *

• Timmer A. Environmental influences on inflammatory bowel disease manifestations. Lessons from epidemiology. Dig. Dis. 21: 91-104 (2003).

• Timmer A, Kemptner D, Takses A, Klebl F, Jockel KH. A survey-based index was validated for measuring disease activity in inflammatory bowel disease. An evaluation study. J. Clin. Epidemiol. 62: 771-778 (2009).

• Tissandie E, Gueguen Y, Lobaccaro JM, Grandcolas L, Aigueperse J, Gourmelon P, Souidi M. Enriched uranium affects the expression of vitamin D receptor and retinoid X receptor in rat kidney. J. Steroid Biochem. Mol. Biol. 110: 263-268 (2008).

• Tissandie E, Gueguen Y, Lobaccaro JM, Grandcolas L, Grison S, Aigueperse J, Souidi M. Vitamin D metabolism impairment in the rat's offspring following maternal exposure to (137)cesium. Arch. Toxicol. 83: 357-362 (2009). *

• Tlacuilo-Parra JA, Guevara-Gutierrez E, Salazar-Paramo M. Acquired ichthyosis associated with systemic lupus erythematosus. Lupus 13: 270-273 (2004).

• Tobon GJ, Youinou P, Saraux A. The environment, geo-epidemiology, and autoimmune disease: rheumatoid arthritis. Autoimmun. Rev. Nov 25 [Epub ahead of print] (2009).

• Tomaiuolo R, Sangiuolo F, Bombieri C, Bonizzato A, Cardillo G, Raia V, D'Apice MR, Bettin MD, Pignatti PF, Castaldo G, Novelli G. Epidemiology and a novel procedure for large scale analysis of CFTR rearrangements in classic and atypical CF patients: a multicentric Italian study. J. Cyst. Fibros. 7: 347-351 (2008).

• Tomer Y. Hepatitis C and interferon induced thyroiditis. J. Autoimmun. Dec 16 [Epub ahead of print] (2009).

• Tomer Y, Blackard JT, Akeno N. Interferon alpha treatment and thyroid dysfunction. Endocrinol. Metab. Clin. North Am. 36: 1051-1066 (2007).

• Tomer Y, Menconi F. Interferon induced thyroiditis. Best Pract. Res. Clin. Endocrinol. Metab. 23: 703-712 (2009).

• Ton TG, Longstreth WT Jr, Koepsell T. Active and passive smoking and risk of narcolepsy in people with HLA DQB1*0602: a population-based case-control study. Neuroepidemiology 32: 114-121 (2008).

• Toro J, Sarmiento OL, Diaz Del Castillo A, Satizabal CL, Ramirez JD, Montenegro AC, Gongora MC, Quinones JA, Diaz A, Tobon A. Prevalence of multiple sclerosis in Bogota, Colombia. Neuroepidemiology 28: 33-38 (2006).

• Tosh K, Campbell SJ, Fielding K, Sillah J, Bah B, Gustafson P, Manneh K, Lisse I, Sirugo G, Bennett S, Aaby P, McAdam KP, Bah-Sow O, Lienhardt C, Kramnik I, Hill AV. Variants in the SP110 gene are associated with genetic susceptibility to tuberculosis in West Africa. Proc. Natl. Acad. Sci. U.S.A. 103: 10364-10368 (2006). *

• Toth C, McDonald D, Oger J, Brownell K. Acetylcholine receptor antibodies in myasthenia gravis are associated with greater risk of diabetes and thyroid disease. Acta Neurol. Scand. 114: 124-132 (2006). *

• Toth PP, Harper CR, Jacobson TA. Clinical characterization and molecular mechanisms of statin myopathy. Expert Rev. Cardiovasc. Ther. 6: 955-969 (2008).

• Townes JM, Deodhar AA, Laine ES, Smith K, Krug HE, Barkhuizen A, Thompson ME, Cieslak PR, Sobel J. Reactive arthritis following culture-confirmed infections with bacterial enteric pathogens in Minnesota and Oregon: a population-based study. Ann. Rheum. Dis. 67: 1689-1696 (2008).

• Tragnone A, Corrao G, Miglio F, Caprilli R, Lanfranchi GA. Incidence of inflammatory bowel disease in Italy: a nationwide population-based study. Gruppo Italiano per lo Studio del Colon e del Retto (GISC). Int. J. Epidemiol. 25: 1044-1052 (1996). *

• Tran T, Davila JA, El-Serag HB. The epidemiology of malignant gastrointestinal stromal tumors: an analysis of 1,458 cases from 1992 to 2000. Am. J. Gastroenterol. 100: 162-168 (2005). *

• Traunmuller F. Etiology of Crohn's disease: do certain food additives cause intestinal inflammation by molecular mimicry of mycobacterial lipids? Med. Hypotheses 65: 859-864 (2005).

• Treem WR. Emerging concepts in celiac disease. Curr. Opin. Pediatr. 16: 552-559 (2004).

• Tremlett HL, Devonshire VA. Does the season or month of birth influence disease progression in multiple sclerosis? Neuroepidemiology 26: 195-198 (2006).

• Triantafillidis JK, Nasioulas G, Kosmidis PA. Colorectal cancer and inflammatory bowel disease: epidemiology, risk factors, mechanisms of carcinogenesis and prevention strategies. Anticancer Res. 29: 2727-2737 (2009).

• Trichopoulou A, Bamia C, Trichopoulos D. Anatomy of health effects of Mediterranean diet: Greek EPIC prospective cohort study. BMJ 338: b2337 (2009). *

• Triger DR, Berg PA, Rodes J. Epidemiology of primary biliary cirrhosis. Liver 4: 195-200 (1984).

• Truong H, Dibello JR, Ruiz-Narvaez E, Kraft P, Campos H, Baylin A. Does genetic variation in the Delta6-desaturase promoter modify the association between alpha-linolenic acid and the prevalence of metabolic syndrome? Am. J. Clin. Nutr. 89: 920-925 (2009). *

• Tsilidis KK, Helzlsouer KJ, Smith MW, Grinberg V, Hoffman-Bolton J, Clipp SL, Visvanathan K, Platz EA. Association of common polymorphisms in IL10, and in other genes related to inflammatory response and obesity with colorectal cancer. Cancer Causes Control 20: 1739-1751 (2009).

• Tummler B, Bosshammer J, Breitenstein S, Brockhausen I, Gudowius P, Herrmann C, Herrmann S, Heuer T, Kubesch P, Mekus F, Romling U, Schmidt KD, Spangenberg C, Walter S. Infections with Pseudomonas aeruginosa in patients with cystic fibrosis. Behring Inst. Mitt. 98: 249-255 (1997).

• Tuncman G, Erbay E, Hom X, De Vivo I, Campos H, Rimm EB, Hotamisligil GS. A genetic variant at the fatty acid-binding protein aP2 locus reduces the risk for hypertriglyceridemia, type 2 diabetes, and cardiovascular disease. Proc. Natl. Acad. Sci. U.S.A. 103: 6970-6975 (2006). *

• Tung J, Loftus EV Jr, Freese DK, El-Youssef M, Zinsmeister AR, Melton LJ 3rd, Harmsen WS, Sandborn WJ, Faubion WA Jr. A population-based study of the frequency of corticosteroid resistance and dependence in pediatric patients with Crohn's disease and ulcerative colitis. Inflamm. Bowel Dis. 12: 1093-1100 (2006). *

• Tworoger SS, Gate MA, Lee IM, Buring JE, Titus-Ernstoff L, Cramer D, Hankinson SE. Polymorphisms in the vitamin D receptor and risk of ovarian cancer in four studies. Cancer Res. 69: 1885-1891 (2009). *

• Ubeda JV. Comparative features of the epidemiology of multiple sclerosis and Parkinson's disease: environmental factors of potential etiological importance. J. Neurol. Sci. 262: 54-59 (2007).

• Ucisik-Akkaya E, Davis CF, Gorodezky C, Alaez C, Dorak MT. HLA complex-linked heat shock protein genes and childhood acute lymphoblastic leukemia susceptibility. Cell Stress Chaperones Dec 14 [Epub ahead of print] (2009). *

• Ucisik-Akkaya E, Dorak MT. A study of natural killer cell lectin-like receptor K1 gene (KLRK1/NKG2D) region polymorphisms in a European population sample. Tissue Antigens 73: 177-183 (2009). *

• Uibo R, Salupere V. The epidemiology of primary biliary cirrhosis: immunological problems. Hepatogastroenterology 46: 3048-3052 (1999).

• Uknis ME. Prophylaxis of cytomegalovirus disease in transplant patients. Am. J. Health Syst. Pharm. 62 Suppl. 1: S3-S6 (2005).

• Umar RK, Rinella ME. An update on nonalcoholic fatty liver disease. Gastroenterology & Hepatology Annual Review Vol. 1, June 2006, p. 94-98 (2006). *

• Urne FU, Paerregaard A. Chronic inflammatory bowel disease in children. An epidemiological study from eastern Denmark 1998-2000. Ugeskr. Laeger. 164: 5810-5814 (2002).

• Vaccarino V, Brennan ML, Miller AH, Bremner JD, Ritchie JC, Lindau F, Veledar E, Su S, Murrah NV, Jones L, Jawed F, Dai J, Goldberg J, Hazen SL. Association of major depressive disorder with serum myeloperoxidase and other markers of inflammation: a twin study. Biol. Psychiatry 64: 476-483 (2008).

• Valdes AM, Spector TD. The genetic epidemiology of osteoarthritis. Curr. Opin. Rheumatol. Jan 19 [Epub ahead of print] (2010).

• Valdes AM, Thomson G, Barcellos LF. Genetic variation within the HLA class III influences T1D susceptibility conferred by high-risk HLA haplotypes. Genes Immun. Jan 7 [Epub ahead of print] (2010).

• van der Deure WM, Friesema EC, de Jong FJ, de Rijke YB, de Jong FH, Uitterlinden AG, Breteler MM, Peeters RP, Visser TJ. Organic anion transporter 1B1: an important factor in hepatic thyroid hormone and estrogen transport and metabolism. Endocrinology 149: 4695-4701 (2008). *

• van der Linden MW, van der Slik AR, Zanelli E, Giphart MJ, Pieterman E, Schreuder GM, Westendorp RG, Huizinga TW. Six microsatellite markers on the short arm of chromosome 6 in relation to HLA-DR3 and TNF-308A in systemic lupus erythematosus. Genes Immun. 2: 373-380 (2001). *

• van der Meer IM, Boeke AJ, Lips P, Grootjans-Geerts I, Wuister JD, Deville WL, Wielders JP, Bouter LM, Middelkoop BJ. Fatty fish and supplements are the greatest modifiable contributors to the serum 25-hydroxyvitamin D concentration in a multiethnic population. Clin. Endocrinol. (Oxf.) 68: 466-472 (2008). *

• van der Net JB, Isaacs A, Dallinga-Thie GM, Kastelein JJ, Defesche JC, Steyerberg EW, Sijbrands EJ. Haplotype of the angiotensinogen gene is associated with coronary heart disease in familial hypercholesterolemia. J. Hypertens. 26: 462-467 (2008).

• van Durme YM, Verhamme KM, Aarnoudse AJ, Van Pottelberge GR, Hofman A, Witteman JC, Joos GF, Brusselle GG, Stricker BH. C-reactive protein levels, haplotypes, and the risk of incident chronic obstructive pulmonary disease. Am. J. Respir. Crit. Care Med. 179: 375-382 (2009). *

• van Heel DA, West J. Recent advances in coeliac disease. Gut 55: 1037-1046 (2006). *

• van Meurs JB, Trikalinos TA, Ralston SH, Balcells S, Brandi ML, Brixen K, Kiel DP, Langdahl BL, Lips P, Ljunggren O, Lorenc R, Obermayer-Pietsch B, Ohlsson C, Pettersson U, Reid DM, Rousseau F, Scollen S, Van Hul W, Agueda L, Akesson K, et al. Large-scale analysis of association between LRP5 and LRP6 variants and osteoporosis. JAMA 299: 1277-1290 (2008). *

• van Munster BC, Korevaar JC, de Rooij SE, Levi M, Zwinderman AH. Genetic polymorphisms related to delirium tremens: a systematic review. Alcohol. Clin. Exp. Res. 31: 177-184 (2007).

• van Os E, van den Broek WW, Mulder PG, ter Borg PC, Bruijn JA, van Buuren HR. Depression in patients with primary biliary cirrhosis and primary sclerosing cholangitis. J. Hepatol. 46: 1099-1103 (2007). *

• van Staa TP. The pathogenesis, epidemiology and management of glucocorticoid-induced osteoporosis. Calcif. Tissue Int. 79: 129-137 (2006). *

• van Staa TP, Cooper C, Brusse LS, Leufkens H, Javaid MK, Arden NK. Inflammatory bowel disease and the risk of fracture. Gastroenterology 125: 1591-1597 (2003). *

• van Winsen LM, Manenschijn L, van Rossum EF, Crusius BA, Koper JW, Polman CH, Uitdehaag BM. A glucocorticoid receptor gene haplotype (TthIII1/ER22/23EK/9beta) is associated with a more aggressive disease course in multiple sclerosis. J. Clin. Endocrinol. Metab. 94: 2110-2114 (2009). *

• Vanacore N. Epidemiological evidence on multiple system atrophy. J. Neural. Transm. 112: 1605-1612 (2005).

• Varas-Lorenzo C, Maguire A, Castellsague J, Perez-Gutthann S. Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level. Pharmacoepidemiol. Drug Saf. 16: 366-376 (2007).

• Varela-Lema L, Taioli E, Ruano-Ravina A, Barros-Dios JM, Anantharaman D, Benhamou S, Boccia S, Bhisey RA, Cadoni G, Capoluongo E, Chen CJ, Foulkes WD, Goloni-Bertollo EM, Hatagima A, Hayes RB, Katoh T, Koifman S, Lazarus P, Manni JJ, Mahimkar M, et al. Meta-analysis and pooled analysis of GSTM1 and CYP1A1 polymorphisms and oral and pharyngeal cancers: a HuGE-GSEC review. Genet. Med. 10: 369-384 (2008).

• Vasoo S. Drug-induced lupus: an update. Lupus 15: 757-761 (2006). *

• Vatn MH. Natural history and complications of IBD. Curr. Gastroenterol. Rep. 11: 481-487 (2009).

• Vatn MH. Mucosal healing: impact on the natural course or therapeutic strategies. Dig. Dis. 27: 470-475 (2009).

• Veale DJ, FitzGerald O. Psoriatic arthritis - pathogenesis and epidemiology. Clin. Exp. Rheumatol. 20: S27-S33 (2002).

• Velayos FS, Terdiman JP, Walsh JM. Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am. J. Gastroenterol. 100: 1345-1353 (2005). *

• Veldkamp MC, Rauws EA, Dijkgraaf MG, Fockens P, Bruno MJ. Iatrogenic ampullary stenosis: history, endoscopic management, and outcome in a series of 49 patients. Gastrointest. Endosc. 66: 708-716 (2007).

• Vender RL. Cystic fibrosis lung disease in adult patients. Postgrad. Med. 120: 64-74 (2008).

• Venegas M, Beltran CJ, Alvarez L, Castro A, Torres T, Leal AD, Lahsen FM, Hermoso MA, Quera R. IL-23R Arg381Gln polymorphism in Chilean patients with inflammatory bowel disease. Eur. Cytokine Netw. 19: 190-195 (2008).

• Venstrom JM, Zheng J, Noor N, Danis KE, Yeh AW, Cheung IY, Dupont B, O'Reilly RJ, Cheung NK, Hsu KC. KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma. Clin. Cancer Res. 15: 7330-7334 (2009). *

• Vergani D, Mieli-Vergani G. Chapter 20. Autoimmune hepatitis. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 263-275 (2007). *

• Vergison A, Denis O, Deplano A, Casimir G, Claeys G, Debaets F, Deboeck K, Douat N, Franckx H, Gigi J, Ieven M, Knoop C, Lebeque P, Lebrun F, Malfroot A, Paucquay F, Pierard D, Van Eldere J, Struelens MJ. National survey of molecular epidemiology of Staphylococcus aureus colonization in Belgian cystic fibrosis patients. J. Antimicrob. Chemother. 59: 893-899 (2007). *

• Vernier G, Cortot A, Gower-Rousseau C, Salomez JL, Colombel JF. Epidemiology and risk factors of inflammatory bowel diseases. Rev. Prat. 55: 949-961 (2005).

• Verstraeten T, Davis R, DeStefano F. Immunity to tetanus is protective against the development of multiple sclerosis. Med. Hypotheses 65: 966-969 (2005).

• Villa-Manzano AI, Gamez-Nava JI, Salazar-Paramo M, Valera-Gonzalez IC, Garcia-Gonzalez A, Garcia-Gonzalez G, Morales-Romero J, Lopez-Olivo A, Galvan-Ramirez LM, Ruiz-Ruvalcaba R, Cardona-Munoz EG, Gonzalez-Lopez L. Serum concentrations of aminoterminal propeptide of type III procollagen and propeptide of human type I procollagen in systemic lupus erythematosus. Rheumatol. Int. 26: 712-716 (2006). *

• Villar J, Perez-Mendez L, Flores C, Maca-Meyer N, Espinosa E, Muriel A, Sanguesa R, Blanco J, Muros M, Kacmarek RM; for the GRECIA and GEN-SEP Groups. A CXCL2 polymorphism is associated with better outcomes in patients with severe sepsis. Crit. Care Med. 35: 2292-2297 (2007).

• Vimaleswaran KS, Radha V, Anjana M, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. Effect of polymorphisms in the PPARGC1A gene on body fat in Asian Indians. Int. J. Obes. (Lond.) 30: 884-891 (2006). *

• Vimaleswaran KS, Radha V, Ghosh S, Majumder PP, Rao MR, Mohan V. A haplotype at the UCP1 gene locus contributes to genetic risk for type 2 diabetes in Asian Indians (CURES-72). Metab. Syndr. Relat. Disord. Nov 29 [Epub ahead of print] (2009).

• Vimaleswaran KS, Radha V, Jayapriya MG, Ghosh S, Majumder PP, Rao MR, Mohan V. Evidence for an association with type 2 diabetes mellitus at the PPARG locus in a South Indian population. Metabolism Oct 19 [Epub ahead of print] (2009). *

• Vimaleswaran KS, Radha V, Mohan V. Thr54 allele carriers of the Ala54Thr variant of FABP2 gene have associations with metabolic syndrome and hypertriglyceridemia in urban South Indians. Metabolism 55: 1222-1226 (2006). *

• Vimaleswaran KS, Radha V, Ramya K, Babu HN, Savitha N, Roopa V, Monalisa D, Deepa R, Ghosh S, Majumder PP, Rao MR, Mohan V. A novel association of a polymorphism in the first intron of adiponectin gene with type 2 diabetes, obesity and hypoadiponectinemia in Asian Indians. Hum. Genet. 123: 599-605 (2008). *

• Vineis P. Misuse of genetic data in environmental epidemiology. Ann. N. Y. Acad. Sci. 1076: 163-167 (2006). *

• Vineis P, Miligi L, Costantini AS. Exposure to solvents and risk of non-Hodgkin lymphoma: clues on putative mechanisms. Cancer Epidemiol. Biomarkers Prev. 16: 381-384 (2007). *

• Visvanathan K, Gallicchio L, Schilling C, Babus JK, Lewis LM, Miller SR, Zacur H, Flaws JA. Cytochrome gene polymorphisms, serum estrogens, and hot flushes in midlife women. Obstet. Gynecol. 106: 1372-1381 (2005).

• Voiculescu M, Winkler RE, Moscovici M, Neuman MG. Chemotherapies and targeted therapies in advanced hepatocellular carcinoma: from laboratory to clinic. J. Gastrointestin. Liver Dis. 17: 315-322 (2008). *

• Voko Z, Bereczky Z, Katona E, Adany R, Muszbek L. Factor XIII Val34Leu variant protects against coronary artery disease. A meta-analysis. Thromb. Haemost. 97: 458-463 (2007).

• Vollmert C, Illig T, Altmuller J, Klugbauer S, Loesgen S, Dumitrescu L, Wjst M. Single nucleotide polymorphism screening and association analysis - exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthma. Clin. Exp. Allergy 34: 1841-1850 (2004). *

• von Schacky C. Omega-3 fatty acids and cardiovascular disease. Curr. Opin. Clin. Nutr. Metab. Care 10: 129-135 (2007).

• von Tirpitz C, Steder-Neukamm U, Glas K, Sander S, Ring C, Klaus J, Reinshagen M. Osteoporosis in inflammatory bowel disease - results of a survey among members of the German Crohn's & Ulcerative Colitis Association. Z. Gastroenterol. 41: 1145-1150 (2003).

• Vuppalanchi R, Liangpunsakul S, Chalasani N. Etiology of new-onset jaundice: how often is it caused by idiosyncratic drug-induced liver injury in the United States? Am. J. Gastroenterol. 102: 558-562 (2007). *

• Vyse AJ, Andrews NJ, Hesketh LM, Pebody R. The burden of parvovirus B19 infection in women of childbearing age in England and Wales. Epidemiol. Infect. 135: 1354-1362 (2007).

• Waaijenborg S, Zwinderman AH. Associating multiple longitudinal traits with high-dimensional single-nucleotide polymorphism data: application to the Framingham Heart Study. BMC Proc. 3 Suppl. 7: S47 (2009). *

• Wagman LD, Robertson JM, O'Neil B. Chapter 15. Liver, gallbladder, and biliary tract cancers. In "Cancer Management: A Multidisciplinary Approach" (Wagman L, Venook AP, Robertson JR, O’Neil BH eds.), Fifth Edition, p. 303-321 (2001). *

• Wahner AD, Glatt CE, Bronstein JM, Ritz B. Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease. Neurosci. Lett. 413: 274-278 (2007). *

• Wahner AD, Sinsheimer JS, Bronstein JM, Ritz B. Inflammatory cytokine gene polymorphisms and increased risk of Parkinson disease. Arch. Neurol. 64: 836-840 (2007). *

• Waite N, Lodge J, Hart K, Robertson D, Badley E, Burton S. The impact of fish-oil supplements on insulin sensitivity. J. Hum. Nutr. Diet. 21: 402-403 (2008). *

• Waldron LS, Ferrari BC, Gillings MR, Power ML. Terminal restriction length polymorphism for identification of Cryptosporidium species in human feces. Appl. Environ. Microbiol. 75: 108-112 (2009). *

• Walker AM, Bohn RL, Cali C, Cook SF, Ajene AN, Sands BE. Risk factors for colon ischemia. Am. J. Gastroenterol. 99: 1333-1337 (2004). *

• Wang C, Tang J, Song W, Lobashevsky E, Wilson CM, Kaslow RA. HLA and cytokine gene polymorphisms are independently associated with responses to hepatitis B vaccination. Hepatology 39: 978-988 (2004). *

• Wang D, Ma J, Zhang S, Hinney A, Hebebrand J, Wang Y, Wang HJ. Association of the MC4R V103I polymorphism with obesity: a Chinese case-control study and meta-analysis in 55,195 individuals. Obesity (Silver Spring) Aug 20 [Epub ahead of print] (2009). *

• Wang J, Pan HF, Hu YT, Zhu Y, He Q. Polymorphism of IL-8 in 251 allele and gastric cancer susceptibility: a meta-analysis. Dig. Dis. Sci. Sep 24 [Epub ahead of print] (2009). *

• Wang J, Yang S, Chen JJ, Zhou SM, He SM, Liang YH, Meng W, Yan XF, Liu JJ, Ye DQ, Zhang XJ. Systemic lupus erythematosus: a genetic epidemiology study of 695 patients from China. Arch. Dermatol. Res. 298: 485-491 (2007). *

• Wang JP. Epidemiology and surgical treatment of Crohn disease. Zhonghua Wei Chang Wai Ke Za Zhi 10: 199-201 (2007).

• Wang K, Chen Z, Tadesse MG, Glessner J, Grant SF, Hakonarson H, Bucan M, Li M. Modeling genetic inheritance of copy number variations. Nucleic Acids Res. 36: e138 (2008). *

• Wang L, Chen W, Wang J, Tan Y, Zhou Y, Ding W, Hua Z, Shen J, Xu Y, Shen H. Reduced folate carrier gene G80A polymorphism is associated with an increased risk of gastroesophageal cancers in a Chinese population. Eur. J. Cancer 42: 3206-3211 (2006). *

• Wang L, Miao X, Tan W, Lu X, Zhao P, Zhao X, Shan Y, Li H, Lin D. Genetic polymorphisms in methylenetetrahydrofolate reductase and thymidylate synthase and risk of pancreatic cancer. Clin. Gastroenterol. Hepatol. 3: 743-751 (2005).

• Wang M, Chen X, Zhang M, Zhu W, Cho K, Zhang H. Detecting significant single-nucleotide polymorphisms in a rheumatoid arthritis study using random forests. BMC Proc. 3 Suppl. 7: S69 (2009). *

• Wang M, Wang M, Cheng G, Zhang Z, Fu G, Zhang Z. Genetic variants in the death receptor 4 gene contribute to susceptibility to bladder cancer. Mutat. Res. 661: 85-92 (2009).

• Wang MH, Helzlsouer KJ, Smith MW, Hoffman-Bolton JA, Clipp SL, Grinberg V, De Marzo AM, Isaacs WB, Drake CG, Shugart YY, Platz EA. Association of IL10 and other immune response- and obesity-related genes with prostate cancer in CLUE II. Prostate 69: 874-885 (2009).

• Wang Q, Ye D, Yin J, Li X, Zhang G, Zhang Y, Zhang X. Programmed cell death 1 genotypes are associated with susceptibility to systemic lupus erythematosus among Chinese. Arch. Dermatol. Res. 300: 91-93 (2008). *

• Wang S. Epidemiology of vitamin D in health and disease. Nutr. Res. Rev. 22: 188-203 (2009).

• Wang SS, Cerhan JR, Hartge P, Davis S, Cozen W, Severson RK, Chatterjee N, Yeager M, Chanock SJ, Rothman N. Common genetic variants in proinflammatory and other immunoregulatory genes and risk for non-Hodgkin lymphoma. Cancer Res. 66: 9771-9780 (2006). *

• Wang SS, Purdue MP, Cerhan JR, Zheng T, Menashe I, Armstrong BK, Lan Q, Hartge P, Kricker A, Zhang Y, Morton LM, Vajdic CM, Holford TR, Severson RK, Grulich A, Leaderer BP, Davis S, Cozen W, Yeager M, Chanock SJ, Chatterjee N, Rothman N. Common gene variants in the tumor necrosis factor (TNF) and TNF receptor superfamilies and NF-kB transcription factors and non-Hodgkin lymphoma risk. PLoS ONE 4: e5360 (2009). *

• Wang X, Ria M, Kelmenson PM, Eriksson P, Higgins DC, Samnegard A, Petros C, Rollins J, Bennet AM, Wiman B, de Faire U, Wennberg C, Olsson PG, Ishii N, Sugamura K, Hamsten A, Forsman-Semb K, Lagercrantz J, Paigen B. Positional identification of TNFSF4, encoding OX40 ligand, as a gene that influences atherosclerosis susceptibility. Nat. Genet. 37: 365-372 (2005). *

• Ward EM, Thun MJ, Hannan LM, Jemal A. Interpreting cancer trends. Ann. N. Y. Acad. Sci. 1076: 29-53 (2006). *

• Warny M, Pepin J, Fang A, Killgore G, Thompson A, Brazier J, Frost E, McDonald LC. Toxin production by an emerging strain of Clostridium difficile associated with outbreaks of severe disease in North America and Europe. Lancet 366: 1079-1084 (2005). *

• Warren RB, Smith RL, Campalani E, Eyre S, Smith CH, Barker JN, Worthington J, Griffiths CE. Genetic variation in efflux transporters influences outcome to methotrexate therapy in patients with psoriasis. J. Invest. Dermatol. 128: 1925-1929 (2008). *

• Warren S, Svenson L, Woodhead S, Warren KG. Parental ancestry and risk of multiple sclerosis in Alberta, Canada. Neuroepidemiology 15: 1-9 (1996).

• Warren S, Svenson LW, Warren KG, Metz LM, Patten SB, Schopflocher DP. Incidence of multiple sclerosis among First Nations people in Alberta, Canada. Neuroepidemiology 28: 21-27 (2006).

• Warren S, Warren KG, Svenson LW, Schopflocher DP, Jones A. Geographic and temporal distribution of mortality rates for multiple sclerosis in Canada, 1965-1994. Neuroepidemiology 22: 75-81 (2003).

• Watanabe N, Takabayashi K. Recent investigations on the basis of pathogenesis of SLE and new therapeutic approaches. Nippon Rinsho 67: 500-505 (2009).

• Watanabe T, Nagawa H. Epidemiology of ulcerative colitis - comparison between Japan and Western countries. Nippon Rinsho 63: 750-756 (2005).

• Watkins PB, Seligman PJ, Pears JS, Avigan MI, Senior JR. Using controlled clinical trials to learn more about acute drug-induced liver injury. Hepatology 48: 1680-1689 (2008). *

• Watts R, Lane S, Hanslik T, Hauser T, Hellmich B, Koldingsnes W, Mahr A, Segelmark M, Cohen Tervaert JW, Scott DG. Development and validation of a consensus methodology for the classification of the ANCA-associated vasculitides and polyarteritis nodosa for epidemiological studies. Ann. Rheum. Dis. 66: 222-227 (2007). *

• Watts RA, Scott DG. Epidemiology of the vasculitides. Semin. Respir. Crit. Care Med. 25: 455-464 (2004).

• Watts RA, Scott DG, Lane SE. Epidemiology of Wegener's granulomatosis, microscopic polyangiitis, and Churg-Strauss syndrome. Cleve. Clin. J. Med. 69 Suppl. 2: SII84-SII86 (2002).

• Weber DJ, Rutala WA. The emerging nosocomial pathogens Cryptosporidium, Escherichia coli O157:H7, Helicobacter pylori, and hepatitis C: epidemiology, environmental survival, efficacy of disinfection, and control measures. Infect. Control Hosp. Epidemiol. 22: 306-315 (2001). *

• Weersma RK, Stokkers PC, Cleynen I, Wolfkamp SC, Henckaerts L, Schreiber S, Dijkstra G, Franke A, Nolte IM, Rutgeerts P, Wijmenga C, Vermeire S. Confirmation of multiple Crohn's disease susceptibility loci in a large Dutch-Belgian cohort. Am. J. Gastroenterol. 104: 630-638 (2009). *

• Weig M, Brown AJ. Genomics and the development of new diagnostics and anti-Candida drugs. Trends Microbiol. 15: 310-317 (2007). *

• Weinstein SJ, Albanes D, Selhub J, Graubard B, Lim U, Taylor PR, Virtamo J, Stolzenberg-Solomon R. One-carbon metabolism biomarkers and risk of colon and rectal cancers. Cancer Epidemiol. Biomarkers Prev. 17: 3233-3240 (2008). *

• Weinstein SJ, Gridley G, Harty LC, Diehl SR, Brown LM, Winn DM, Bravo-Otero E, Hayes RB. Folate intake, serum homocysteine and methylenetetrahydrofolate reductase (MTHFR) C677T genotype are not associated with oral cancer risk in Puerto Rico. J. Nutr. 132: 762-767 (2002). *

• Weinstock MA, Bingham SF, Lew RA, Hall R, Eilers D, Kirsner R, Naylor M, Kalivas J, Cole G, Marcolivio K, Collins J, Digiovanna JJ, Vertrees JE; for the Veterans Affairs Topical Tretinoin Chemoprevention (VATTC) Trial Group. Topical tretinoin therapy and all-cause mortality. Arch. Dermatol. 145: 18-24 (2009). *

• Weinstock MA, Lee KC, Chren MM, Marcolivio K; VATTC Trial Group. Quality of life in the actinic neoplasia syndrome: the VA Topical Tretinoin Chemoprevention (VATTC) Trial. J. Am. Acad. Dermatol. 61: 207-215 (2009).

• Weiss ST, Litonjua AA. Maternal diet vs lack of exposure to sunlight as the cause of the epidemic of asthma, allergies and other autoimmune diseases. Thorax 62: 745-746 (2007). *

• Wellcome Trust Case Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447: 661-678 (2007). *

• Wellcome Trust Case Control Consortium & The Australo-Anglo-American Spondylitis Consortium. Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants. Nat. Genet. 39: 1329-1337 (2007). *

• Wells G, Boers M, Tugwell P. Low disease activity state in rheumatoid arthritis: concepts and derivation of minimal disease activity. Clin. Exp. Rheumatol. 24: S052-S059 (2006). *

• Welsh MM, Applebaum KM, Spencer SK, Perry AE, Karagas MR, Nelson HH. CTLA4 variants, UV-induced tolerance, and risk of non-melanoma skin cancer. Cancer Res. 69: 6158-6163 (2009). *

• Welzel TM, Gao X, Pfeiffer RM, Martin MP, O'Brien SJ, Goedert JJ, Carrington M, O'Brien TR. HLA-B Bw4 alleles and HIV-1 transmission in heterosexual couples. AIDS 21: 225-229 (2007).

• Welzel TM, Graubard BI, El-Serag HB, Shaib YH, Hsing AW, Davila JA, McGlynn KA. Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: a population-based case-control study. Clin. Gastroenterol. Hepatol. 5: 1221-1228 (2007).

• Welzel TM, Mellemkjaer L, Gloria G, Sakoda LC, Hsing AW, Ghormli LE, Olsen JH, McGlynn KA. Risk factors for intrahepatic cholangiocarcinoma in a low-risk population: a nationwide case-control study. Int. J. Cancer 120: 638-641 (2007). *

• Werner M, Herbon N, Gohlke H, Altmuller J, Knapp M, Heinrich J, Wjst M. Asthma is associated with single-nucleotide polymorphisms in ADAM33. Clin. Exp. Allergy 34: 26-31 (2004).

• Werner M, Prytz H, Ohlsson B, Almer S, Bjornsson E, Bergquist A, Wallerstedt S, Sandberg-Gertzen H, Hultcrantz R, Sangfelt P, Weiland O, Danielsson A. Epidemiology and the initial presentation of autoimmune hepatitis in Sweden: a nationwide study. Scand. J. Gastroenterol. 43: 1232-1240 (2008). *

• Werth VP, Berlin JA, Callen JP, Mick R, Sullivan KE. Mannose binding lectin (MBL) polymorphisms associated with low MBL production in patients with dermatomyositis. J. Invest. Dermatol. 119: 1394-1399 (2002). *

• West J. Celiac disease and its complications: a time traveler's perspective. Gastroenterology 136: 32-34 (2009). *

• West J, Logan RF, Card TR, Smith C, Hubbard R. Fracture risk in people with celiac disease: a population-based cohort study. Gastroenterology 125: 429-436 (2003). *

• West J, Logan RF, Hill PG, Khaw KT. The iceberg of celiac disease: what is below the waterline? Clin. Gastroenterol. Hepatol. 5: 59-62 (2007).

• West J, Logan RF, Hubbard RB, Card TR. Risk of schizophrenia in people with coeliac disease, ulcerative colitis and Crohn's disease: a general population-based study. Aliment. Pharmacol. Ther. 23: 71-74 (2006). *

• West J, Logan RF, Smith CJ, Hubbard RB, Card TR. Malignancy and mortality in people with coeliac disease: population based cohort study. BMJ 329: 716-719 (2004). *

• West J, Wood H, Logan RF, Quinn M, Aithal GP. Trends in the incidence of primary liver and biliary tract cancers in England and Wales 1971-2001. Br. J. Cancer 94: 1751-1758 (2006). *

• West NA, Haan MN, Morgenstern H. The PPAR-gamma Pro12Ala polymorphism and risk of cognitive impairment in a longitudinal study. Neurobiol. Aging Jul 16 [Epub ahead of print] (2008).

• Weyermann M, Rothenbacher D, Brenner H. Acquisition of Helicobacter pylori infection in early childhood: independent contributions of infected mothers, fathers, and siblings. Am. J. Gastroenterol. 104: 182-189 (2009). *

• Wheeldon TU, Hoang TT, Phung DC, Bjorkman A, Granstrom M, Sorberg M. Helicobacter pylori eradication and peptic ulcer healing: the impact of deleting the proton pump inhibitor and using a once-daily treatment. Aliment. Pharmacol. Ther. 18: 93-100 (2003). *

• Whelan CT, Kaboli P, Zhang Q, Siddique J, Ye S, Meltzer DO. Upper gastrointestinal hemorrhage: have new therapeutics made a difference? J. Hosp. Med. 4: E6-E10 (2009).

• Whelan G. Epidemiology of inflammatory bowel disease. Med. Clin. North Am. 74: 1-12 (1990).

• Whitaker JK, West J, Holmes GK, Logan RF. Patient perceptions of the burden of coeliac disease and its treatment in the UK. Aliment. Pharmacol. Ther. 29: 1131-1136 (2009). *

• Whitcomb DC. Genetic polymorphisms in alcoholic pancreatitis. Dig. Dis. 23: 247-254 (2005).

• Whitcomb DC. Gene-environment factors that contribute to alcoholic pancreatitis in humans. J. Gastroenterol. Hepatol. 21 Suppl. 3: S52-S55 (2006). *

• White JM, O'Connor S, Winter HS, Heyman MB, Kirschner BS, Ferry GD, Cohen SA, Baldassano RN, Smith T, Clemons T, Gold BD. Inflammatory bowel disease in African-American children compared with other racial/ethnic groups in a multicenter registry. Clin. Gastroenterol. Hepatol. 6: 1361-1369 (2008).

• Whitehead WE, Borrud L, Goode PS, Meikle S, Mueller ER, Tuteja A, Weidner A, Weinstein M, Ye W; Pelvic Floor Disorders Network. Fecal incontinence in U.S. adults: epidemiology and risk factors. Gastroenterology 137: 512-517.e1-e2 (2009). *

• Wiener HW, Perry RT, Chen Z, Harrell LE, Go RC. A polymorphism in SOD2 is associated with development of Alzheimer's disease. Genes Brain Behav. 6: 770-775 (2007).

• Wiest MM, German JB, Harvey DJ, Watkins SM, Hertz-Picciotto I. Plasma fatty acid profiles in autism: a case-control study. Prostaglandins Leukot. Essent. Fatty Acids 80: 221-227 (2009). *

• Wilcox M, Li Q, Sun Y, Stang P, Berlin J, Wang D. Genome-wide association study for empirically derived metabolic phenotypes in the Framingham Heart Study offspring cohort. BMC Proc. 3 Suppl. 7: S53 (2009). *

• Wilkening S, Bermejo JL, Hemminki K. MDM2 SNP309 and cancer risk: a combined analysis. Carcinogenesis 28: 2262-2267 (2007). *

• Willer CJ, Dyment DA, Cherny S, Ramagopalan SV, Herrera BM, Morrison KM, Sadovnick AD, Risch NJ, Ebers GC. A genome-wide scan in forty large pedigrees with multiple sclerosis. J. Hum. Genet. 52: 955-962 (2007). *

• Willers SM, Devereux G, Craig LC, McNeill G, Wijga AH, Abou El-Magd W, Turner SW, Helms PJ, Seaton A. Maternal food consumption during pregnancy and asthma, respiratory and atopic symptoms in 5-year-old children. Thorax 62: 772-778 (2007). *

• Williams FM, Spector T. The genetics of osteoporosis. Acta Reumatol. Port. 32: 231-240 (2007). *

• Williams FM, Spector TD. Recent advances in the genetics of osteoporosis. J. Musculoskelet. Neuronal Interact. 6: 27-35 (2006).

• Williams JJ, Beck PL, Andrews CN, Hogan DB, Storr MA. Microscopic colitis - a common cause of diarrhoea in older adults. Age Ageing 39: 162-168 (2010).

• Williams MA, Frederick IO, Qiu C, Meryman LJ, King IB, Walsh SW, Sorensen TK. Maternal erythrocyte omega-3 and omega-6 fatty acids, and plasma lipid concentrations, are associated with habitual dietary fish consumption in early pregnancy. Clin. Biochem. 39: 1063-1070 (2006). *

• Williams R, Chen YF, Endres R, Middleton D, Trucco M, Williams JD, Knowler W. Molecular variation at the HLA-A, B, C, DRB1, DQA1, and DQB1 loci in full heritage American Indians in Arizona: private haplotypes and their evolution. Tissue Antigens Oct 21 [Epub ahead of print] (2009). *

• Williamson DM. Studies of multiple sclerosis in communities concerned about environmental exposures. J. Womens Health (Larchmt.) 15: 810-814 (2006).

• Wilson FC, Icen M, Crowson CS, McEvoy MT, Gabriel SE, Kremers HM. Time trends in epidemiology and characteristics of psoriatic arthritis over 3 decades: a population-based study. J. Rheumatol. 36: 361-367 (2009).

• Wilson JW, du Bois RM, King TE Jr. Challenges in pulmonary fibrosis: 8 - The need for an international registry for idiopathic pulmonary fibrosis. Thorax 63: 285-287 (2008).

• Winkelmayer WC, Huber A, Wagner OF, Horl WH, Sunder-Plassmann G, Fodinger M. Associations between MTHFR 1793G>A and plasma total homocysteine, folate, and vitamin B in kidney transplant recipients. Kidney Int. 67: 1980-1985 (2005).

• Winkelmayer WC, Kramar R, Sunder-Plassmann G, Fodinger M. Effects of single-nucleotide polymorphisms in MTHFR and MTRR on mortality and allograft loss in kidney transplant recipients. Kidney Int. 68: 2857-2862 (2005).

• Winkler C, Illig T, Koczwara K, Bonifacio E, Ziegler AG. HHEX-IDE polymorphism is associated with low birth weight in offspring with a family history of type 1 diabetes. J. Clin. Endocrinol. Metab. 94: 4113-4115 (2009).

• Wirtenberger M, Tchatchou S, Hemminki K, Schmutzhard J, Sutter C, Schmutzler RK, Meindl A, Wappenschmidt B, Kiechle M, Arnold N, Weber BH, Niederacher D, Bartram CR, Burwinkel B. Associations of genetic variants in the estrogen receptor coactivators PPARGC1A, PPARGC1B and EP300 with familial breast cancer. Carcinogenesis 27: 2201-2208 (2006). *

• Wise CK, Cooney CA, Ali SF, Poirier LA. Measuring S-adenosylmethionine in whole blood, red blood cells and cultured cells using a fast preparation method and high-performance liquid chromatography. J. Chromatogr. B. Biomed. Sci. Appl. 696: 145-152 (1997).

• Witt CM, Ludtke R, Willich SN. Homeopathic treatment of patients with psoriasis - a prospective observational study with 2 years follow-up. J. Eur. Acad. Dermatol. Venereol. 23: 538-543 (2009). *

• Witte JS, Suarez BK, Thiel B, Lin J, Yu A, Banerjee TK, Burmester JK, Casey G, Catalona WJ. Genome-wide scan of brothers: replication and fine mapping of prostate cancer susceptibility and aggressiveness loci. Prostate 57: 298-308 (2003).

• Wojtun S, Gil J, Wichan P, Chojnacki J. Inflammatory bowel diseases - pathogenesis and clinical symptoms. Pol. Merkuriusz. Lek. 17 Suppl. 1: 9-13 (2004).

• Wolf DS, Singer HS. Pediatric movement disorders: an update. Curr. Opin. Neurol. 24: 491-496 (2008).

• Wolfe F, Michaud K. Biologic treatment of rheumatoid arthritis and the risk of malignancy: analyses from a large US observational study. Arthritis Rheum. 56: 2886-2895 (2007). *

• Wolfe F, Michaud K. Lymphoma in rheumatoid arthritis: the effect of methotrexate and anti-tumor necrosis factor therapy in 18,572 patients. Arthritis Rheum. 50: 1740-1751 (2004). *

• Wolfe F, Michaud K. Towards an epidemiology of rheumatoid arthritis outcome with respect to treatment: randomized controlled trials overestimate treatment response and effectiveness. Rheumatology (Oxford) 44 Suppl. 4: iv18-iv22 (2005). *

• Wolfe F, Michaud K. The effect of methotrexate and anti-tumor necrosis factor therapy on the risk of lymphoma in rheumatoid arthritis in 19,562 patients during 89,710 person-years of observation. Arthritis Rheum. 56: 1433-1439 (2007). *

• Wolford JK, Yeatts KA, Red Eagle AR, Nelson RG, Knowler WC, Hanson RL. Variants in the gene encoding aldose reductase (AKR1B1) and diabetic nephropathy in American Indians. Diabet. Med. 23: 367-376 (2006). *

• Wolfson C. Multiple sclerosis and antecedent infections. Epidemiology 12: 298-299 (2001). *

• Wolters FL, Russel MG, Sijbrandij J, Schouten LJ, Odes S, Riis L, Munkholm P, Bodini P, O’Morain C, Mouzas IA, Tsianos E, Vermeire S, Monteiro E, Limonard C, Vatn M, Fornaciari G, Pereira S, Moum B, Stockbrugger RW. Crohn’s disease: increased mortality 10 years after diagnosis in a Europe-wide population based cohort. Gut 55: 510-518 (2006). *

• Wong GL, Hui AY, Wong VW, Chan FK, Sung JJ, Chan HL. A retrospective study on clinical features and prognostic factors of biopsy-proven primary biliary cirrhosis in Chinese patients. Am. J. Gastroenterol. 100: 2205-2211 (2005). *

• World Health Organization. The molecular genetic epidemiology of cystic fibrosis, Report of a joint meeting of WHO/ECFTN/ICF(M)A/ECFS, Genoa, Italy, 19 June 2002, p 1-26. Human Genetics Programme Chronic Diseases and Health Promotion, World Health Organization WHO/HGN/CF/WG/04.02 (http://www.who.int/genomics/publications/en/HGN_WB_04.02_TOC.pdf) (2002). *

• Worthington J. Looking back: developments in our understanding of the genetic epidemiology of rheumatoid arthritis over the last 50 years. Rheumatology (Oxford) 44 Suppl. 4: iv5-iv8 (2005). *

• Worthington J. Investigating the genetic basis of susceptibility to rheumatoid arthritis. J. Autoimmun. 25: S16-S20 (2005).

• Worthington J, John S. Association of PADI4 and rheumatoid arthritis: a successful multidisciplinary approach. Trends Mol. Med. 9: 405-407 (2003). *

• Wu CC, Shete S, Chen WV, Peng B, Lee AT, Ma J, Gregersen PK, Amos CI. Detection of disease-associated deletions in case-control studies using SNP genotypes with application to rheumatoid arthritis. Hum. Genet. 126: 303-315 (2009). *

• Wu TT, Chen YF, Hastie T, Sobel E, Lange K. Genomewide association analysis by lasso penalized logistic regression. Bioinformatics 25: 714-721 (2009).

• Wu X, Jin L, Xiong M. Composite measure of linkage disequilibrium for testing interaction between unlinked loci. Eur. J. Hum. Genet. 16: 644-651 (2008). *

• Wu X, Ye Y, Kiemeney LA, Sulem P, Rafnar T, Matullo G, Seminara D, Yoshida T, Saeki N, Andrew AS, Dinney CP, Czerniak B, Zhang ZF, Kiltie AE, Bishop DT, Vineis P, Porru S, Buntinx F, Kellen E, Zeegers MP, Kumar R, Rudnai P, Gurzau E, Koppova K, et al. Genetic variation in the prostate stem cell antigen gene PSCA confers susceptibility to urinary bladder cancer. Nat. Genet. 41: 991-995 (2009). *

• Wu Z, Aporntewan C, Ballard DH, Lee JY, Lee JS, Zhao H. Two-stage joint selection method to identify candidate markers from genome-wide association studies. BMC Proc. 3 Suppl. 7: S29 (2009). *

• Xia G, Pan F, Liao F, Tang X, Ge R, Mei Y, Pan H, Xu S, Xu J. No significant association between Fc receptor-like 3 gene polymorphisms and human leukocyte antigen-B27 positive ankylosing spondylitis in Han Chinese population. Mol. Biol. Rep. Aug 6 [Epub ahead of print] (2009). *

• Xing C, Gray-McGuire C, Kelly JA, Garriott P, Bukulmez H, Harley JB, Olson JM. Genetic linkage of systemic lupus erythematosus to 13q32 in African American families with affected male members. Hum. Genet. 118: 309-321 (2005). *

• Xing C, Sestak AL, Kelly JA, Nguyen KL, Bruner GR, Harley JB, Gray-McGuire C. Localization and replication of the systemic lupus erythematosus linkage signal at 4p16: interaction with 2p11, 12q24 and 19q13 in European Americans. Hum. Genet. 120: 623-631 (2007). *

• Xu CJ, Zhang WH, Pan HF, Li XP, Xu JH, Ye DQ. Association study of a single nucleotide polymorphism in the exon 2 region of Toll-like receptor 9 (TLR9) gene with susceptibility to systemic lupus erythematosus among Chinese. Mol. Biol. Rep. 36: 2245-2248 (2009). *

• Xu H, Shete S. Effects of population structure on genetic association studies. BMC Genet. 6 Suppl. 1: S109 (2005). *

• Xu J, Wang Y, Pan F, Stankovich J, Ye D, Lian L, Zhang K, Ding C. Association of ACE gene polymorphism with genetic susceptibility to systemic lupus erythematosus in a Chinese population: a family-based association study. J. Rheumatol. 34: 2408-2411 (2007).

• Xu W, Tamim H, Shapiro S, Stang MR, Collet JP. Use of antidepressants and risk of colorectal cancer: a nested case-control study. Lancet Oncol. 7: 301-308 (2006).

• Xu X, Gammon MD, Zeisel SH, Bradshaw PT, Wetmur JG, Teitelbaum SL, Neugut AI, Santella RM, Chen J. High intakes of choline and betaine reduce breast cancer mortality in a population-based study. FASEB J. 23: 4022-4028 (2009). *

• Xu X, Gammon MD, Zeisel SH, Lee YL, Wetmur JG, Teitelbaum SL, Bradshaw PT, Neugut AI, Santella RM, Chen J. Choline metabolism and risk of breast cancer in a population-based study. FASEB J. 22: 2045-2052 (2008). *

• Xu XX, Shui X, Chen ZH, Shan CQ, Hou YN, Cheng YG. Development and application of a real-time PCR method for pharmacokinetic and biodistribution studies of recombinant adenovirus. Mol. Biotechnol. 43: 130-137 (2009). *

• Yaddanapudi K, Hornig M, Serge R, De Miranda J, Baghban A, Villar G, Lipkin WI. Passive transfer of Streptococcus-induced antibodies reproduces behavioral disturbances in a mouse model of pediatric autoimmune neuropsychiatric disorders associated with streptococcal infection. Mol. Psychiatry Aug 11 [Epub ahead of print] (2009).

• Yaghi C, Sharara AI, Rassam P, Moucari R, Honein K, Boujaoude J, Slim R, Noun R, Abdul-Baki H, Khalifeh M, Ramia S, Sayegh R. Hepatocellular carcinoma in Lebanon: etiology and prognostic factors associated with short-term survival. World J. Gastroenterol. 12: 3575-3580 (2006). *

• Yaghoobi M, Farrokhyar F, Yuan Y, Hunt RH. Is there an increased risk of GERD after Helicobacter pylori eradication?: a meta-analysis. Am. J. Gastroenterol. Jan 19 [Epub ahead of print] (2010). *

• Yamagishi K, Iso H, Date C, Fukui M, Wakai K, Kikuchi S, Inaba Y, Tanabe N, Tamakoshi A; JACC Study Group. Fish, omega-3 polyunsaturated fatty acids, and mortality from cardiovascular diseases in a nationwide community-based cohort of Japanese men and women: the JACC (Japan Collaborative Cohort Study for Evaluation of Cancer Risk) study. J. Am. Coll. Cardiol. 52: 988-996 (2008).

• Yamagishi K, Nettleton JA, Folsom AR; for the ARIC Study Investigators. Plasma fatty acid composition and incident heart failure in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) study. Am. Heart J. 156: 965-974 (2008).

• Yamaji T, Iwasaki M, Sasazuki S, Sakamoto H, Yoshida T, Tsugane S. Methionine synthase A2756G polymorphism interacts with alcohol and folate intake to influence the risk of colorectal adenoma. Cancer Epidemiol. Biomarkers Prev. 18: 267-274 (2009).

• Yamamoto T, Nakahigashi M, R Saniabadi A. Review article: diet and inflammatory bowel disease - epidemiology and treatment. Aliment. Pharmacol. Ther. 30: 99-112 (2009). *

• Yamamoto-Furusho JK. Clinical epidemiology of ulcerative colitis in Mexico: a single hospital-based study in a 20-year period (1987-2006). J. Clin. Gastroenterol. 43: 221-224 (2009).

• Yamano Y, Takenouchi N, Li HC, Tomaru U, Yao K, Grant CW, Maric DA, Jacobson S. Virus-induced dysfunction of CD4(+)CD25(+) T cells in patients with HTLV-I-associated neuroimmunological disease. J. Clin. Invest. 115: 1361-1368 (2005). *

• Yamashita TS, Khan MA, Kushner I. Genetic analysis of families with multiple cases of rheumatoid arthritis. Dis. Markers 4: 113-119 (1986).

• Yan M, Rerko RM, Platzer P, Dawson D, Willis J, Tong M, Lawrence E, Lutterbaugh J, Lu S, Willson JK, Luo G, Hensold J, Tai HH, Wilson K, Markowitz SD. 15-Hydroxyprostaglandin dehydrogenase, a COX-2 oncogene antagonist, is a TGF-beta-induced suppressor of human gastrointestinal cancers. Proc. Natl. Acad. Sci. U.S.A. 101: 17468-17473 (2004). *

• Yan Y, North KE, Ballantyne CM, Brancati FL, Chambless LE, Franceschini N, Heiss G, Kottgen A, Pankow JS, Selvin E, West SL, Boerwinkle E. Transcription factor 7-like 2 (TCF7L2) polymorphism and context-specific risk of type 2 diabetes in African American and Caucasian adults: The Atherosclerosis Risk in Communities (ARIC) study. Diabetes 58: 285-289 (2009). *

• Yang A, Chen Y, Scherl E, Neugut AI, Bhagat G, Green PH. Inflammatory bowel disease in patients with celiac disease. Inflamm. Bowel Dis. 11: 528-532 (2005). *

• Yang CX, Takezaki T, Hirose K, Inoue M, Huang XE, Tajima K. Fish consumption and colorectal cancer: a case-reference study in Japan. Eur. J. Cancer Prev. 12: 109-115 (2003).

• Yang H, Taylor KD, Rotter JI. Inflammatory bowel disease. I. Genetic epidemiology. Mol. Genet. Metab. 74: 1-21 (2001). *

• Yang H, Testa JR, Carbone M. Mesothelioma epidemiology, carcinogenesis, and pathogenesis. Curr. Treat. Options Oncol. 9: 147-157 (2008).

• Yang H, Zhou Y, Zhou Z, Liu J, Yuan X, Matsuo K, Takezaki T, Tajima K, Cao J. A novel polymorphism rs1329149 of CYP2E1 and a known polymorphism rs671 of ALDH2 of alcohol metabolizing enzymes are associated with colorectal cancer in a Southwestern Chinese population. Cancer Epidemiol. Biomarkers Prev. 18: 2522-2527 (2009). *

• Yang IA, Savarimuthu S, Kim ST, Holloway JW, Bell SC, Fong KM. Gene-environmental interaction in asthma. Curr. Opin. Allergy Clin. Immunol. 7: 75-82 (2007).

• Yang M, Sun T, Wang L, Yu D, Zhang X, Miao X, Liu J, Zhao D, Li H, Tan W, Lin D. Functional variants in cell death pathway genes and risk of pancreatic cancer. Clin. Cancer Res. 14: 3230-3236 (2008). *

• Yang S, Yang J, Liu JB, Wang HY, Yang Q, Gao M, Liang YH, Lin GS, Lin D, Hu XL, Fan L, Zhang XJ. The genetic epidemiology of alopecia areata in China. Br. J. Dermatol. 151: 16-23 (2004). *

• Yang SK, Loftus EV Jr, Sandborn WJ. Epidemiology of inflammatory bowel disease in Asia. Inflamm. Bowel Dis. 7: 260-270 (2001). *

• Yang SK, Yun S, Kim JH, Park JY, Kim HY, Kim YH, Chang DK, Kim JS, Song IS, Park JB, Park ER, Kim KJ, Moon G, Yang SH. Epidemiology of inflammatory bowel disease in the Songpa-Kangdong district, Seoul, Korea, 1986-2005: a KASID study. Inflamm. Bowel Dis. 14: 542-549 (2008). *

• Yang XR, Jacobs K, Kerstann KF, Bergen AW, Goldstein AM, Goldin LR. Linkage analysis of the GAW14 simulated dataset with microsatellite and single-nucleotide polymorphism markers in large pedigrees. BMC Genet. 6 Suppl. 1: S14 (2005). *

• Yang XR, Kerstann KF, Bergen AW, Goldstein AM, Goldin LR. Linkage analysis of anti-CCP levels as dichotomized and quantitative traits using GAW15 single-nucleotide polymorphism scan of NARAC families. BMC Proc. 1 Suppl. 1: S107 (2007). *

• Yang XR, Ng D, Alcorta DA, Liebsch NJ, Sheridan E, Li S, Goldstein AM, Parry DM, Kelley MJ. T (brachyury) gene duplication confers major susceptibility to familial chordoma. Nat. Genet. 41: 1176-1178 (2009). *

• Yang YX. Do diabetes drugs modify the risk of pancreatic cancer? Gastroenterology 137: 412-415 (2009). *

• Yawn BP, Gazzuola L, Wollan PC, Kim WR. Development and maintenance of a community-based hepatitis C registry. Am. J. Manag. Care 8: 253-261 (2002). *

• Yawn BP, Wollan P, Gazzuola L, Kim WR. Diagnosis and 10-year follow-up of a community-based hepatitis C cohort. J. Fam. Pract. 51: 135-140 (2002). *

• Yazdanpanah M, Sayed-Tabatabaei FA, Hofman A, Aulchenko YS, Oostra BA, Stricker BH, Pols HA, Lamberts SW, Witteman JC, Janssen JA, van Duijn CM. The alpha-adducin gene is associated with macrovascular complications and mortality in patients with type 2 diabetes. Diabetes 55: 2922-2927 (2006). *

• Ye DQ, Hu YS, Li XP, Yang SG, Hao JH, Huang F, Zhang XJ. The correlation between monocyte chemoattractant protein-1 and the arthritis of systemic lupus erythematosus among Chinese. Arch. Dermatol. Res. 296: 366-371 (2005). *

• Ye DQ, Yang SG, Li XP, Hu YS, Yin J, Zhang GQ, Liu HH, Wang Q, Zhang KC, Dong MX, Zhang XJ. Polymorphisms in the promoter region of RANTES in Han Chinese and their relationship with systemic lupus erythematosus. Arch. Dermatol. Res. 297: 108-113 (2005). *

• Ye DQ, Yin J, Li XP, Zhang GQ, Zhang YQ, Wang Q, Liu HH. The analysis on single nucleotide polymorphism of PDCD1 and systemic lupus erythematous susceptibility among Han indigenous in Chinese population. Zhonghua Liu Xing Bing Xue Za Zhi 26: 698-701 (2005).

• Ye Y, Yang H, Grossman HB, Dinney C, Wu X, Gu J. Genetic variants in cell cycle control pathway confer susceptibility to bladder cancer. Cancer 112: 2467-2474 (2008). *

• Ye Y, Zhong X, Zhang H. A genome-wide tree- and forest-based association analysis of comorbidity of alcoholism and smoking. BMC Genet. 6 Suppl. 1: S135 (2005). *

• Yeager M, Chatterjee N, Ciampa J, Jacobs KB, Gonzalez-Bosquet J, Hayes RB, Kraft P, Wacholder S, Orr N, Berndt S, Yu K, Hutchinson A, Wang Z, Amundadottir L, Feigelson HS, Thun MJ, et al. Identification of a new prostate cancer susceptibility locus on chromosome 8q24. Nat. Genet. 41: 1055-1057 (2009). *

• Yeatman TJ. Colon cancer. ENCYCLOPEDIA OF LIFE SCIENCES Nature Publishing Group www.els.net (2001). *

• Yee LJ. Host genetic determinants in hepatitis C virus infection. Genes Immun. 5: 237-245 (2004). *

• Yee LJ, Im K, Borg B, Yang H, Liang TJ. Interleukin-6 haplotypes and the response to therapy of chronic hepatitis C virus infection. Genes Immun. 10: 365-372 (2009).

• Yee LJ, Im K, Wahed AS, Bugawan T, Li J, Rhodes SL, Erlich H, Rosen HR, Liang TJ, Yang H; for the Virahep-C Study. Polymorphism in the human major histocompatibility complex and early viral decline during treatment of chronic hepatitis C. Antimicrob. Agents Chemother. 53: 615-621 (2009). *

• Yee LJ, Tang J, Herrera J, Kaslow RA, van Leeuwen DJ. Tumor necrosis factor gene polymorphisms in patients with cirrhosis from chronic hepatitis C virus infection. Genes Immun. 1: 386-390 (2000). *

• Yee YK, Tan VP, Chan P, Hung IF, Pang R, Wong BC. Epidemiology of colorectal cancer in Asia. J. Gastroenterol. Hepatol. 24: 1810-1816 (2009). *

• Yen AW, Fancher TL, Bowlus CL. Revisiting hereditary hemochromatosis: current concepts and progress. Am. J. Med. 119: 391-399 (2006). *

• Yin L, Grandi N, Raum E, Haug U, Arndt V, Brenner H. Meta-analysis: longitudinal studies of serum vitamin D and colorectal cancer risk. Aliment. Pharmacol. Ther. 30: 113-125 (2009). *

• Yin M, Wei S, Wei Q. Vitamin D receptor genetic polymorphisms and prostate cancer risk: a meta-analysis of 36 published studies. Int. J. Clin. Exp. Med. 2: 159-175 (2009).

• Yoneyama S, Miura K, Sasaki S, Yoshita K, Morikawa Y, Ishizaki M, Kido T, Naruse Y, Nakagawa H. Dietary intake of fatty acids and serum C-reactive protein in Japanese. J. Epidemiol. 17: 86-92 (2007). *

• Youinou P, Pers JO, Gershwin ME, Shoenfeld Y. Geo-epidemiology and autoimmunity. J. Autoimmun. Dec 26 [Epub ahead of print] (2009).

• Yu KJ, Gao X, Chen CJ, Yang XR, Diehl SR, Goldstein A, Hsu WL, Liang XS, Marti D, Liu MY, Chen JY, Carrington M, Hildesheim A. Association of human leukocyte antigens (HLA) with nasopharyngeal carcinoma (NPC) in high-risk multiplex families in Taiwan. Hum. Immunol. 70: 910-914 (2009).

• Yu RB, Hong X, Ding WL, Tan YF, Zhang YX, Sun NX, Wu GL, Zhan SW, Ge DF. The association between the genetic polymorphism of HLA-DQA1, DQB1, and DRB1 and serum alanine aminotransferase levels in chronic hepatitis C in the Chinese population. J. Gastroenterol. Hepatol. 23: 1394-1402 (2008). *

• Yu X, Jacobs DR Jr, Schreiner PJ, Gross MD, Steffes MW, Fornage M. The uncoupling protein 2 Ala55Val polymorphism is associated with diabetes mellitus: the CARDIA study. Clin. Chem. 51: 1451-1456 (2005). *

• Yum SY, Yum SK, Kim T, Hwang MY. Clinical perspectives on autoimmune processes in schizophrenia. Psychiatr. Clin. North Am. 32: 795-808 (2009).

• Yun HR, Lee SO, Choi EJ, Shin HD, Jun JB, Bae SC. Cyclooxygenase-2 polymorphisms and risk of rheumatoid arthritis in Koreans. J. Rheumatol. 35: 763-769 (2008).

• Yun J, Xu CT, Pan BR. Epidemiology and gene markers of ulcerative colitis in the Chinese. World J. Gastroenterol. 15: 788-803 (2009). *

• Zaba R, Grzybowski A, Prokop J, Zaba Z, Zaba C. Fournier's gangrene: historical survey, current status, and case description. Med. Sci. Monit. 15: CS34-CS39 (2009). *

• Zagari RM, Law GR, Fuccio L, Cennamo V, Gilthorpe MS, Forman D, Bazzoli F. Epidemiology of functional dyspepsia and subgroups in the Italian general population: an endoscopic study. Gastroenterology Jan 11 [Epub ahead of print] (2010). *

• Zajicek J. The epidemiology of multiple sclerosis. J. Neurol. 254: 1742 (2007).

• Zaki Mel S, Hassan SA, Seleim T, Lateef RA. Parvovirus B19 infection in children with a variety of hematological disorders. Hematology 11: 261-266 (2006).

• Zaridze DG. Molecular epidemiology of cancer. Biochemistry (Mosc.) 73: 532-542 (2008).

• Zecevic M, Amos CI, Gu X, Campos IM, Jones JS, Lynch PM, Rodriguez-Bigas MA, Frazier ML. IGF1 gene polymorphism and risk for hereditary nonpolyposis colorectal cancer. J. Natl. Cancer Inst. 98: 139-143 (2006). *

• Zee RY, Hegener HH, Gould J, Ridker PM. Toll-like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis. Stroke 36: 154-157 (2005). *

• Zee RY, Mora S, Cheng S, Erlich HA, Lindpaintner K, Rifai N, Buring JE, Ridker PM. Homocysteine, 5,10-methylenetetrahydrofolate reductase 677C>T polymorphism, nutrient intake, and incident cardiovascular disease in 24,968 initially healthy women. Clin. Chem. 53: 845-851 (2007). *

• Zeitler P. Update on nonautoimmune diabetes in children. J. Clin. Endocrinol. Metab. 94: 2215-2220 (2009). *

• Zell JA, Ziogas A, Ignatenko N, Honda J, Qu N, Bobbs AS, Neuhausen SL, Gerner EW, Anton-Culver H. Associations of a polymorphism in the ornithine decarboxylase gene with colorectal cancer survival. Clin. Cancer Res. 15: 6208-6216 (2009).

• Zendehdel K, Bahmanyar S, McCarthy S, Nyren O, Andersson B, Ye W. Genetic polymorphisms of glutathione S-transferase genes GSTP1, GSTM1, and GSTT1 and risk of esophageal and gastric cardia cancers. Cancer Causes Control Jul 18 [Epub ahead of print] (2009). *

• Zhang H, Zhao H, Merikangas K. Strategies to identify genes for complex diseases. Ann. Med. 29: 493-498 (1997).

• Zhang L, Miyaki K, Araki J, Nakayama T, Muramatsu M. The relation between nicotinamide N-methyltransferase gene polymorphism and plasma homocysteine concentration in healthy Japanese men. Thromb. Res. 121: 55-58 (2007). *

• Zhang L, Miyaki K, Nakayama T, Muramatsu M. Cell death-inducing DNA fragmentation factor alpha-like effector A (CIDEA) gene V115F (G-->T) polymorphism is associated with phenotypes of metabolic syndrome in Japanese men. Metabolism 57: 502-505 (2008). *

• Zhang M, Ardlie K, Wacholder S, Welch R, Chanock S, O'Brien TR. Genetic variations in CC chemokine receptors and hypertension. Am. J. Hypertens. 19: 67-72 (2006).

• Zhang M, Schmid S, Carrington M, O'Brien TR. Antibodies to varicella-zoster virus in blood donors with genetic variance in CC chemokine receptor 5. Lancet 359: 1034-1036 (2002). *

• Zhang QY. Retinoic acid biosynthetic activity and retinoid receptors in the olfactory mucosa of adult mice. Biochem. Biophys. Res. Commun. 256: 346-351 (1999). *

• Zhang Y, Holford TR, Leaderer B, Zahm SH, Boyle P, Morton LM, Zhang B, Zou K, Flynn S, Tallini G, Owens PH, Zheng T. Prior medical conditions and medication use and risk of non-Hodgkin lymphoma in Connecticut United States women. Cancer Causes Control 15: 419-428 (2004). *

• Zhang YY, Gottardo L, Thompson R, Powers C, Nolan D, Duffy J, Marescotti MC, Avogaro A, Doria A. A visfatin promoter polymorphism is associated with low-grade inflammation and type 2 diabetes. Obesity (Silver Spring) 14: 2119-2126 (2006). *

• Zhao XF, Pan HF, Yuan H, Zhang WH, Li XP, Wang GH, Wu GC, Su H, Pan FM, Li WX, Li LH, Chen GP, Ye DQ. Increased serum interleukin 17 in patients with systemic lupus erythematosus. Mol. Biol. Rep. 37: 81-85 (2010). *

• Zhao ZZ, Nyholt DR, Le L, Thomas S, Engwerda C, Randall L, Treloar SA, Montgomery GW. Genetic variation in tumour necrosis factor and lymphotoxin is not associated with endometriosis in an Australian sample. Hum. Reprod. 22: 2389-2397 (2007). *

• Zheng SL, Sun J, Wiklund F, Smith S, Stattin P, Li G, Adami HO, Hsu FC, Zhu Y, Balter K, Kader AK, Turner AR, Liu W, Bleecker ER, Meyers DA, Duggan D, Carpten JD, Chang BL, Isaacs WB, Xu J, Gronberg H. Cumulative association of five genetic variants with prostate cancer. N. Engl. J. Med. 358: 910-919 (2008). *

• Zheng W, Long J, Gao YT, Li C, Zheng Y, Xiang YB, Wen W, Levy S, Deming SL, Haines JL, Gu K, Fair AM, Cai Q, Lu W, Shu XO. Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1. Nat. Genet. 41: 324-328 (2009). *

• Zheng Z, Jia Y, Hou L, Persson C, Yeager M, Lissowska J, Chanock SJ, Blaser M, Chow WH, Ye W. Genetic variation in a4GnT in relation to Helicobacter pylori serology and gastric cancer risk. Helicobacter 14: 120-125 (2009). *

• Zheng Z, Nordenstedt H, Pedersen NL, Lagergren J, Ye W. Lifestyle factors and risk for symptomatic gastroesophageal reflux in monozygotic twins. Gastroenterology 132: 87-95 (2007). *

• Zhou W, Pool V, Iskander JK, English-Bullard R, Ball R, Wise RP, Haber P, Pless RP, Mootrey G, Ellenberg SS, Braun MM, Chen RT. Surveillance for safety after immunization: Vaccine Adverse Event Reporting System (VAERS) - United States, 1991-2001. MMWR Surveill. Summ. 52: 1-24 (2003).

• Zhou X, Chen W, Swartz MD, Lu Y, Yu R, Amos CI, Wu CC, Shete S. Joint linkage and imprinting analyses of GAW15 rheumatoid arthritis and gene expression data. BMC Proc. 1 Suppl. 1: S53 (2007). *

• Zhu Y, Wang J, He Q, Zhang JQ. The association between interleukin-10-592 polymorphism and gastric cancer risk: a meta-analysis. Med. Oncol. Jan 20 [Epub ahead of print] (2010). *

• Ziegler TR, Cole CR. Small bowel bacterial overgrowth in adults: a potential contributor to intestinal failure. Curr. Gastroenterol. Rep. 9: 463-467 (2007).

• Zigra PI, Maipa VE, Alamanos YP. Probiotics and remission of ulcerative colitis: a systematic review. Neth. J. Med. 65: 411-418 (2007). *

• Zink A, Listing J. Risk of serious bacterial infection: treatment with anti-TNF versus methotrexate. Nat. Clin. Pract. Rheumatol. 3: 546-547 (2007). *

• Zipris D. Epidemiology of type 1 diabetes and what animal models teach us about the role of viruses in disease mechanisms. Clin. Immunol. 131: 11-23 (2009). *

• Zmuda JM, Modugno F, Weissfeld JL, Cauley JA, Trump DL, Moffett SP, Ferrell RE. Peroxisome proliferator-activated receptor-gamma polymorphism, body mass and prostate cancer risk: evidence for gene-environment interaction. Oncology 70: 185-189 (2006).

• Zmuda JM, Sheu YT, Moffett SP. Genetic epidemiology of osteoporosis: past, present, and future. Curr. Osteoporos. Rep. 3: 111-115 (2005).

• Zoccali C, Mallamaci F, Tripepi G. It is important to lower homocysteine in dialysis patients. Semin. Dial. 20: 530-533 (2007).

• Zopf Y, Rabe C, Kollmann S, Hahn EG, Thurauf N, Schwab D. Alterations of taste perception in Crohn's disease and their dependency on disease activity and nutritional behavior. J. Clin. Gastroenterol. 43: 617-621 (2009).

• Zotova E, Lyrenas L, Faire UD, Morgenstern R, Gigante B, Bennet AM. The myeloperoxidase gene and its influence on myocardial infarction in a Swedish population: protective role of the -129A allele in women. Coron. Artery Dis. 20: 322-326 (2009).

Number of references = 2374

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