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Scientific Literature, biliary transport
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Accatino L, Contreras A, Fernandez S, Quintana C 1979 The effect of complete biliary obstruction on bile flow and bile acid excretion: postcholestatic choleresis in the rat.
J. Lab. Clin. Med. 93: 706-717.
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Accatino L, Hono J, Koenig C, Pizarro M, Rodriguez L 1993 Adaptive changes of hepatic bile salt transport in a model of reversible interruption of the enterohepatic circulation in the rat.
J. Hepatol. 19: 95-104.
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Accatino L, Pizarro M, Solis N, Koenig CS, Vollrath V, Chianale J 1996 Modulation of hepatic content and biliary excretion of P-glycoproteins in hepatocellular and obstructive cholestasis in the rat.
J. Hepatol. 25: 349-361.
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Adachi Y, Kamisako T 1996 Intrahepatic cholestasis.
Nippon Rinsho 54: 788-793.
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Ahmed S, Vo NT, Thalhammer T, Thalhammer F, Gattringer KB, Jager W 2008 Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver.
J. Pharm. Pharmacol. 60: 55-62.
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Akashi M, Tanaka A, Takikawa H 2006 Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats.
Hepatol. Res. 34: 193-198.
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Akita H, Suzuki H, Ito K, Kinoshita S, Sato N, Takikawa H, Sugiyama Y 2001 Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump.
Biochim. Biophys. Acta 1511: 7-16.
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Alnounou M, Munoz SJ 2006 Nutrition Issues In Gastroenterology, Series #37. Nutrition concerns of the patient with primary biliary cirrhosis or primary sclerosing cholangitis. [http://www.healthsystem.virginia.edu/internet/digestive-health/nutritionarticles/April2006.pdf]
Practical Gastroenterology April 2006: 92-100. *
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Alpini G, Glaser S, Baiocchi L, Francis H, Xia X, Lesage G 2005 Secretin activation of the apical Na(+)-dependent bile acid transporter is associated with cholehepatic shunting in rats.
Hepatology 41: 1037-1045.
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Alpini G, Lenzi R, Zhai WR, Slott PA, Liu MH, Sarkozi L, Tavoloni N 1989 Bile secretory function of intrahepatic biliary epithelium in the rat.
Am. J. Physiol. 257: G124-G133.
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Alpini G, McGill JM, LaRusso NF 2002 The pathobiology of biliary epithelia.
Hepatology 35: 1256-1268.
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Alvarez L, Jara P, Sanchez-Sabate E, Hierro L, Larrauri J, Diaz MC, Camarena C, De La Vega A, Frauca E, Lopez-Collazo E, Lapunzina P 2004 Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1.
Hum. Mol. Genet. 13: 2451-2460.
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Alvaro D, Benedetti A, Marucci L, Delle Monache M, Monterubbianesi R, Di Cosimo E, Perego L, Macarri G, Glaser S, Le Sage G, Alpini G 2000 The function of alkaline phosphatase in the liver: regulation of intrahepatic biliary epithelium secretory activities in the rat.
Hepatology 32: 174-184.
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Aly A, Carlson K, Johansson C, Kirstein P, Rossner S, Wallentin L 1984 Lipoprotein abnormalities in patients with early primary biliary cirrhosis.
Eur. J. Clin. Invest. 14: 155-162.
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Anelli PL, Lattuada L, Lorusso V, Lux G, Morisetti A, Morosini P, Serleti M, Uggeri F 2004 Conjugates of gadolinium complexes to bile acids as hepatocyte-directed contrast agents for magnetic resonance imaging.
J. Med. Chem. 47: 3629-3641.
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Aoki T 2005 Genetic disorders of copper transport - diagnosis and new treatment for the patients of Wilson's disease.
No To Hattatsu 37: 99-109.
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Arii S 2004 Role of vascular endothelial growth factor on the invasive potential of hepatocellular carcinoma.
J. Hepatol. 41: 333-335.
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Arrese M 2006 Cholestasis during pregnancy: rare hepatic diseases unmasked by pregnancy.
Ann. Hepatol. 5: 216-218.
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Arrese M, Accatino L 2002 From blood to bile: recent advances in hepatobiliary transport.
Ann. Hepatol. 1: 64-71.
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Arrese M, Ananthananarayanan M, Suchy FJ 1998 Hepatobiliary transport: molecular mechanisms of development and cholestasis.
Pediatr. Res. 44: 141-147.
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Arrese M, Macias RI, Briz O, Perez MJ, Marin JJ 2008 Molecular pathogenesis of intrahepatic cholestasis of pregnancy.
Expert Rev. Mol. Med. 10: e9.
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Arrese M, Reyes H 2006 Intrahepatic cholestasis of pregnancy: a past and present riddle.
Ann. Hepatol. 5: 202-205.
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Arrese M, Trauner M 2003 Molecular aspects of bile formation and cholestasis.
Trends Mol. Med. 9: 558-564.
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Asamoto Y, Tazuma S, Ochi H, Chayama K, Suzuki H 2001 Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function.
Biochem. J. 359: 605-610.
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Azer SA 2005 A multimedia CD-ROM tool to improve student understanding of bile salts and bilirubin metabolism: evaluation of its use in a medical hybrid PBL course.
Adv. Physiol. Educ. 29: 40-50.
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Azer SA 2004 Do recommended textbooks contain adequate information about bile salt transporters for medical students?
Adv. Physiol. Educ. 28: 36-43.
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Azer SA, Stacey NH 1996 Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: physiological basis and pathophysiological changes in cholestatic liver dysfunction.
J. Gastroenterol. Hepatol. 11: 396-407.
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Bahar RJ, Stolz A 1999 Bile acid transport.
Gastroenterol. Clin. North Am. 28: 27-58.
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Balasubramaniyan N, Shahid M, Suchy FJ, Ananthanarayanan M 2005 Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development.
Am. J. Physiol. Gastrointest. Liver Physiol. 288: G251-G260.
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Balistreri WF 2003 Genetic liver disease.
54th Annual Meeting of the American Association for the Study of Liver Diseases.
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Balistreri WF 1997 Bile acid therapy in pediatric hepatobiliary disease: the role of ursodeoxycholic acid.
J. Pediatr. Gastroenterol. Nutr. 24: 573-589.
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Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL, Madejczyk MS, Li N 2005 OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia.
Hepatology 42: 1270-1279.
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Ballatori N, Rebbeor JF 1998 Roles of MRP2 and oatp1 in hepatocellular export of reduced glutathione.
Semin. Liver Dis. 18: 377-387.
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Ballatori N, Rebbeor JF, Connolly GC, Seward DJ, Lenth BE, Henson JH, Sundaram P, Boyer JL 2000 Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump.
Am. J. Physiol. Gastrointest. Liver Physiol. 278: G57-G63.
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Barnes DS 2002 Intrahepatic cholestatic liver disease.
http://www.clevelandclinicmeded.com/diseasemanagement/gastro/intrahepatic/intrahepatic1.htm.
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Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken M, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE 2007 Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases.
Drug Metab. Dispos. 35: 1963-1969.
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Beaussier M, Schiffer E, Housset C 2008 Ischaemic cholestasis in intensive care unit.
Ann. Fr. Anesth. Reanim. Aug 28 [Epub ahead of print].
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Behar J, Corazziari E, Guelrud M, Hogan W, Sherman S, Toouli J 2006 Functional disorders of gallbladder and sphincter of oddi.
Gastroenterology 130: 1498-1509.
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Benedetti A, Alvaro D, Bassotti C, Gigliozzi A, Ferretti G, La Rosa T, Di Sario 1997 Cytotoxicity of bile salts against biliary epithelium: a study in isolated bile ductule fragments and isolated perfused rat liver.
Hepatology 26: 9-21.
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Bergasa NV 2005 The pruritus of cholestasis.
J. Hepatol. 43: 1078-1088.
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Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ 2004 Primary biliary cirrhosis: report of a focus study group.
Hepatology 40: 1013-1020.
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Bergman E, Forsell P, Tevell A, Persson EM, Hedeland M, Bondesson U, Knutson L, Lennernas H 2006 Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase.
Eur. J. Pharm. Sci. 29: 205-214.
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Bertolotti M, Gabbi C, Anzivino C, Carulli L, Loria P, Carulli N 2008 Nuclear receptors as potential molecular targets in cholesterol accumulation conditions: insights from evidence on hepatic cholesterol degradation and gallstone disease in humans.
Curr. Med. Chem. 15: 2271-2284.
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Beuers U 2006 Drug insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis.
Nat. Clin. Pract. Gastroenterol. Hepatol. 3: 318-328.
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Beuers U 2006 Mechanisms of action of ursodeoxycholic acid for treatment of primary sclerosing cholangitis.
Falk Workshop "Primary Sclerosing Cholangitis: Complications and Consequences", Moscow (Russia), June 11, 2006, p. 12. *
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Beuers U 2003 Mechanisms of action of ursodeoxycholic acid in cholestasis.
Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper’s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 49-50. October 15-16. *
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Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, Dombrowski F 2001 Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver.
Hepatology 33: 1206-1216.
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Beuers U, Denk GU, Soroka CJ, Wimmer R, Rust C, Paumgartner G, Boyer JL 2003 Taurolithocholic acid exerts cholestatic effects via phosphatidylinositol 3-kinase-dependent mechanisms in perfused rat livers and rat hepatocyte couplets.
J. Biol. Chem. 278: 17810-17818.
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Beukeveld GJ, In 't Veld G, Havinga R, Groen AK, Wolthers BG, Kuipers F 1996 Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport.
J. Hepatol. 24: 343-352.
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Bi YA, Kazolias DC, Duignan DB 2006 Use of cryopreserved human hepatocytes in sandwich-culture to measure hepatobiliary transport.
Drug Metab. Dispos. 34: 1658-1665.
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Bjornsson E, Chapman RW 2003 Sclerosing cholangitis.
Curr. Opin. Gastroenterol. 19: 270-275.
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Bode KA, Donner MG, Leier I, Keppler D 2002 Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate.
Biochem. Pharmacol. 64: 151-158.
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Bohan A, Boyer JL 2002 Mechanisms of hepatic transport of drugs: implications for cholestatic drug reactions.
Semin. Liver Dis. 22: 123-136.
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Bohme M, Jedlitschky G, Leier I, Buchler M, Keppler D 1994 ATP-dependent export pumps and their inhibition by cyclosporins.
Adv. Enzyme Regul. 34: 371-380.
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Bolder U, Thasler WE, Hofmann AF, Jauch KW 1998 Hepatocellular transport of bile acids and organic anions in infection and SIRS - evidence for different mechanisms for regulating membrane transport proteins.
Langenbecks Arch. Chir. Suppl. Kongressbd. 115 (Suppl. I): 391-396.
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Bolder U, Ton-Nu HT, Schteingart CD, Frick E, Hofmann AF 1997 Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion.
Gastroenterology 112: 214-225.
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Bolder U, Trang NV, Hagey LR, Schteingart CD, Ton-Nu HT, Cerre C, Elferink RP, Hofmann AF 1999 Sulindac is excreted into bile by a canalicular bile salt pump and undergoes a cholehepatic circulation in rats.
Gastroenterology 117: 962-971.
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Boyer JL 2005 Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease?
Gastroenterology 129: 735-740.
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Boyer JL 2007 New perspectives for the treatment of cholestasis: lessons from basic science applied clinically.
J. Hepatol. 46: 365-371.
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Boyer JL, Denk G, Bohan A, Chen WS, Soroka C, Denson L 2004 Adaptive regulation of bile salt transporters in cholestasis.
Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 46-47. June 18-19. *
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Brandoni A, Anzai N, Kanai Y, Endou H, Torres AM 2006 Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3.
Biochim. Biophys. Acta 1762: 673-682.
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Brandoni A, Villar SR, Picena JC, Anzai N, Endou H, Torres AM 2006 Expression of rat renal cortical OAT1 and OAT3 in response to acute biliary obstruction.
Hepatology 43: 1092-1100.
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Briz O, Macias RI, Perez MJ, Serrano MA, Marin JJ 2006 Excretion of fetal biliverdin by the rat placenta-maternal liver tandem.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 290: R749-R756.
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Buscher HP, Miltenberger C, MacNelly S, Gerok W 1989 The histoautoradiographic localization of taurocholate in rat liver after bile duct ligation. Evidence for ongoing secretion and reabsorption processes.
J. Hepatol. 8: 181-191.
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Buts JP, De Keyser N, Collette E, Bonsignore M, Lambotte L, Desjeux JF, Sokal EM 1996 Intestinal transport of calcium in rat biliary cirrhosis.
Pediatr. Res. 40: 533-541.
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Buxbaum J, Qian P, Khuu C, Shneider BL, Daikh DI, Gershwin ME, Allen PM, Peters MG 2006 Novel model of antigen-specific induction of bile duct injury.
Gastroenterology 131: 1899-1906.
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Calamita G, Ferri D, Gena P, Liquori GE, Marinelli RA, Meyer G, Portincasa P, Svelto M 2005 Water transport into bile and role in bile formation.
Curr. Drug Targets Immune Endocr. Metabol. Disord. 5: 137-142.
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Calpe-Berdiel L, Escola-Gil JC, Blanco-Vaca F 2008 New insights into the molecular actions of plant sterols and stanols in cholesterol metabolism.
Atherosclerosis Jul 6 [Epub ahead of print].
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Carrella M, Roda E 1999 Evolving concepts in the pathophysiology of biliary lipid secretion.
Ital. J. Gastroenterol. Hepatol. 31: 643-648.
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Cassio D, Macias RI, Grosse B, Marin JJ, Monte MJ 2007 Expression, localization, and inducibility by bile acids of hepatobiliary transporters in the new polarized rat hepatic cell lines, Can 3-1 and Can 10.
Cell Tissue Res. 330: 447-460.
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Cater MA, Forbes J, La Fontaine S, Cox D, Mercer JF 2004 Intracellular trafficking of the human Wilson protein: the role of the six N-terminal metal binding sites.
Biochem. J. 380: 805-813.
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Chandra P, Brouwer KL 2004 The complexities of hepatic drug transport: current knowledge and emerging concepts.
Pharm. Res. 21: 719-735.
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Chandra P, Johnson BM, Zhang P, Pollack GM, Brouwer KL 2005 Modulation of hepatic canalicular or basolateral transport alters hepatobiliary disposition of a model organic anion in the isolated perfused rat liver.
Drug Metab. Dispos. 33: 1238-1243.
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Chaudry G, Navarro OM, Levine DS, Oudjhane K 2006 Abdominal manifestations of cystic fibrosis in children.
Pediatr. Radiol. 36: 233-240.
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Chazouilleres O, Marteau P, Haniche M, Jian R, Poupon R 1996 Ileal absorption of bile acids in patients with chronic cholestasis: SeHCAT test results and effect of ursodeoxycholic acid (UDCA).
Dig. Dis. Sci. 41: 2417-2422.
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Chen HL, Chen HL, Liu YJ, Feng CH, Wu CY, Shyu MK, Yuan RH, Chang MH 2005 Developmental expression of canalicular transporter genes in human liver.
J. Hepatol. 43: 472-477.
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Chen HL, Liu YJ, Chen HL, Wu SH, Ni YH, Ho MC, Lai HS, Hsu WM, Tseng HC, Jeng YM, Chang MH 2008 Expression of hepatocyte transporters and nuclear receptors in children with early and late-stage biliary atresia.
Pediatr. Res. 63: 667-673.
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Chen J, Raymond K 2006 Treatment effect of rifampicin on cholestasis.
The Internet Journal of Pharmacology Vol. 4 (http://www.ispub.com/ostia/index.php?xmlFilePath=journals/ijpharm/vol4n2/colestasis.xml).
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Chignard N, Mergey M, Veissiere D, Parc R, Capeau J, Poupon R, Paul A, Housset C 2001 Bile acid transport and regulating functions in the human biliary epithelium.
Hepatology 33: 496-503.
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Chinet T, Fouassier L, Dray-Charier N, Imam-Ghali M, Morel H, Mergey M, Dousset B, Parc R, Paul A, Housset C 1999 Regulation of electrogenic anion secretion in normal and cystic fibrosis gallbladder mucosa.
Hepatology 29: 5-13.
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Cho WK, Boyer JL 1999 Vasoactive intestinal polypeptide is a potent regulator of bile secretion from rat cholangiocytes.
Gastroenterology 117: 420-428.
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Choi MK, Song IS 2008 Organic cation transporters and their pharmacokinetic and pharmacodynamic consequences.
Drug Metab. Pharmacokinet. 23: 243-253.
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Chu X, Strauss JR, Mariano MA, Li J, Newton DJ, Cai X, Wang RW, Yabut J, Hartley DP, Evans DC, Evers R 2006 Characterization of mice lacking the multidrug resistance protein Mrp2 (Abcc2).
J. Pharmacol. Exp. Ther. 317: 579-589.
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Clerici C, Castellani D, Asciutti S, Pellicciari R, Setchell KD, O'connell NC, Sadeghpour B, Camaioni E, Fiorucci S, Renga B, Nardi E, Sabatino G, Clementi M, Giuliano V, Baldoni M, Orlandi S, Mazzocchi A, Morelli A, Morelli O 2006 3alpha-6alpha-Dihydroxy-7alpha-fluoro-5beta-cholanoate (UPF-680), physicochemical and physiological properties of a new fluorinated bile acid that prevents 17alpha-ethynyl-estradiol-induced cholestasis in rats.
Toxicol. Appl. Pharmacol. 214: 199-208.
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Colombo C 2006 Liver disease in cystic fibrosis.
Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 31-33. *
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Colombo C, Battezzati PM, Strazzabosco M, Podda M 1998 Liver and biliary problems in cystic fibrosis.
Semin. Liver Dis. 18: 227-235.
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Colombo C, Crosignani A, Apostolo MG, Marzano MT, Bettinardi N, Giunta A 1994 Oral bile acids in cystic fibrosis-associated liver disease.
J. R. Soc. Med. 87 Suppl. 21: 20-24.
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Colombo C, Okolicsanyi L, Strazzabosco M 2000 Advances in familial and congenital cholestatic diseases. Clinical and diagnostic implications.
Dig. Liver Dis. 32: 152-159.
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Copaci I, Micu L, Iliescu L, Voiculescu M 2005 New therapeutical indications of ursodeoxycholic acid.
Rom. J. Gastroenterol. 14: 259-266.
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Cornelius CE 1981 Hepatic bilirubin-IX-alpha-glycosyltransferase activities in animals excreting primarily biliverdin into bile.
Vet. Clin. Pathol. 10: 27-31.
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Crocenzi FA, D'Andrea V, Catania VA, Luquita MG, Pellegrino JM, Ochoa JE, Mottino AD, Sanchez Pozzi E 2005 Prevention of Mrp2 activity impairment in ethinylestradiol-induced cholestasis by ursodeoxycholate in the rat.
Drug Metab. Dispos. 33: 888-891.
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Crocenzi FA, Mottino AD, Roma MG 2004 Regulation of synthesis and trafficking of canalicular transporters and its alteration in acquired hepatocellular cholestasis. Experimental therapeutic strategies for its prevention.
Curr. Med. Chem. 11: 501-524.
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Crocenzi FA, Sanchez Pozzi EJ, Pellegrino JM, Rodriguez Garay EA, Mottino AD, Roma MG 2003 Preventive effect of silymarin against taurolithocholate-induced cholestasis in the rat.
Biochem. Pharmacol. 66: 355-364.
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Crosignani A, Podda M, Bertolini E, Battezzati PM, Zuin M, Setchell KD 1991 Failure of ursodeoxycholic acid to prevent a cholestatic episode in a patient with benign recurrent intrahepatic cholestasis: a study of bile acid metabolism.
Hepatology 13: 1076-1083.
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Cui Y, Konig J, Keppler D 2001 Vectorial transport by double-transfected cells expressing the human uptake transporter SLC21A8 and the apical export pump ABCC2.
Mol. Pharmacol. 60: 934-943.
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Cui Y, Konig J, Nies AT, Pfannschmidt M, Hergt M, Franke WW, Alt W, Moll R, Keppler D 2003 Detection of the human organic anion transporters SLC21A6 (OATP2) and SLC21A8 (OATP8) in liver and hepatocellular carcinoma.
Lab. Invest. 83: 527-538.
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Davis HR Jr, Basso F, Hoos LM, Tetzloff G, Lally SM, Altmann SW 2008 Cholesterol homeostasis by the intestine: lessons from Niemann-Pick C1 like 1 (NPC1L1).
Atheroscler. Suppl. Jun 26 [Epub ahead of print].
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de Waart DR, Paulusma CC, Kunne C, Oude Elferink RP 2006 Multidrug resistance associated protein 2 mediates transport of prostaglandin E.
Liver Int. 26: 362-368.
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Demeilliers C, Jacquemin E, Barbu V, Mergey M, Paye F, Fouassier L, Chignard N, Housset C, Lomri NE 2006 Altered hepatobiliary gene expressions in PFIC1: ATP8B1 gene defect is associated with CFTR downregulation.
Hepatology 43: 1125-1134.
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Denson LA, Auld KL, Schiek DS, McClure MH, Mangelsdorf DJ, Karpen SJ 2000 Interleukin-1beta suppresses retinoid transactivation of two hepatic transporter genes involved in bile formation.
J. Biol. Chem. 275: 8835-8843.
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Dietrich CG, Geier A, Oude Elferink RP 2003 ABC of oral bioavailability: transporters as gatekeepers in the gut.
Gut 52: 1788-1795.
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Dietrich CG, Geier A, Wasmuth HE, Matern S, Gartung C, de Waart DR, Elferink RP 2004 Influence of biliary cirrhosis on the detoxification and elimination of a food derived carcinogen.
Gut 53: 1850-1855.
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Doherty MM, Poon K, Tsang C, Pang KS 2006 Transport is not rate-limiting in morphine glucuronidation in the single pass perfused rat liver preparation.
J. Pharmacol. Exp. Ther. 317: 890-900.
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Donner MG, Schumacher S, Warskulat U, Heinemann J, Haussinger D 2007 Obstructive cholestasis induces TNF-alpha- and IL-1beta-mediated periportal down-regulation of Bsep and zonal regulation of Ntcp, Oatp1a4 and Oatp1b2.
Am. J. Physiol. Gastrointest. Liver Physiol. 293: G1134-G1146.
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Dray-Charier N, Paul A, Scoazec JY, Veissiere D, Mergey M, Capeau J, Soubrane O, Housset C 1999 Expression of delta F508 cystic fibrosis transmembrane conductance regulator protein and related chloride transport properties in the gallbladder epithelium from cystic fibrosis patients.
Hepatology 29: 1624-1634.
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Dray-Charier N, Paul A, Veissiere D, Mergey M, Scoazec JY, Capeau J, Brahimi-Horn C, Housset C 1995 Expression of cystic fibrosis transmembrane conductance regulator in human gallbladder epithelial cells.
Lab. Invest. 73: 828-836.
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Drescher S, Glaeser H, Murdter T, Hitzl M, Eichelbaum M, Fromm MF 2003 P-glycoprotein-mediated intestinal and biliary digoxin transport in humans.
Clin. Pharmacol. Ther. 73: 223-231.
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Dutta AK, Woo K, Doctor RB, Fitz JG, Feranchak AP 2008 Extracellular nucleotides stimulate Cl- currents in biliary epithelia through receptor-mediated IP3 and Ca2+ release.
Am. J. Physiol. Gastrointest. Liver Physiol. Sep 11 [Epub ahead of print].
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Duttala S, Tobi M, Dingell JD 2006 Complementary stimulation of hepatobiliary transport and detoxification by rifampicin and ursodeoxycholic acid in humans.
Gastroenterology 130: 619-620.
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Ehret MJ, Levin GM, Narasimhan M, Rathinavelu A 2006 Venlafaxine induces P-glycoprotein in human Caco-2 cells.
Hum. Psychopharmacol. 22: 49-53.
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Elamiri A, Perwaiz S, Tuchweber B, Yousef IM 2003 Effect of mdr2 mutation with combined tandem disruption of canalicular glycoprotein transporters by cyclosporine A on bile formation in mice.
Pharmacol. Res. 48: 467-472.
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Enokizono J, Kusuhara H, Sugiyama Y 2007 Involvement of breast cancer resistance protein (BCRP/ABCG2) in the biliary excretion and intestinal efflux of troglitazone sulfate, the major metabolite of troglitazone with a cholestatic effect.
Drug Metab. Dispos. 35: 209-214.
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Erlinger S 1996 Mechanisms of hepatic transport and bile secretion.
Acta Gastroenterol. Belg. 59: 159-162.
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Fagerholm U 2008 Prediction of human pharmacokinetics-biliary and intestinal clearance and enterohepatic circulation.
J. Pharm. Pharmacol. 60: 535-542.
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Fanni D, Pilloni L, Orru S, Coni P, Liguori C, Serra S, Lai ML, Uccheddu A, Contu L, Van Eyken P, Faa G 2005 Expression of ATP7B in normal human liver.
Eur. J. Histochem. 49: 371-378.
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Fardel O, Payen L, Courtois A, Vernhet L, Lecureur V 2001 Regulation of biliary drug efflux pump expression by hormones and xenobiotics.
Toxicology 167: 37-46.
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Fava G, Marzioni M, Francis H, Glaser S, Demorrrow S, Ueno Y, Benedetti A, Alpini G 2007 Novel interaction of bile acid and neural signaling in the regulation of cholangiocyte function.
Hepatol. Res. 37 Suppl. 3: S420-S429.
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Feranchak AP, Fitz JG 2002 Adenosine triphosphate release and purinergic regulation of cholangiocyte transport.
Semin. Liver Dis. 22: 251-262.
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Feranchak AP, Sokol RJ 2001 Cholangiocyte biology and cystic fibrosis liver disease.
Semin. Liver Dis. 21: 471-488.
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Ferenci P 1998 Wilson's disease.
Clin. Liver Dis. 2: 31-49, v-vi.
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Fernandez E, Galan AI, Moran D, Gonzalez-Buitrago JM, Munoz ME, Jimenez R 1995 Reversal of cyclosporine A-induced alterations in biliary secretion by S-adenosyl-L-methionine in rats.
J. Pharmacol. Exp. Ther. 275: 442-449.
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Fickert P, Fuchsbichler A, Marschall HU, Wagner M, Zollner G, Krause R, Zatloukal K, Jaeschke H, Denk H, Trauner M 2006 Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice.
Am. J. Pathol. 168: 410-422.
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