bile transport, Primary Sclerosing Cholangitis Literature

Primary Sclerosing Cholangitis Literature

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Scientific Literature, bile transport

Abe T, Kakyo M, Tokui T, Nakagomi R, Nishio T, Nakai D, Nomura H, Unno M, Suzuki M, Naitoh T, Matsuno S, Yawo H 1999 Identification of a novel gene family encoding human liver-specific organic anion transporter LST-1. J. Biol. Chem. 274: 17159-17163. *
Abenavoli L, De Maria V, DeSiena M, DiSalvo S, Giancotti F, Gravina T, Abenavoli SM 2007 Familial intrahepatic cholestasis. Novel advances. Recenti Prog. Med. 98: 569-573.
Accatino L, Contreras A, Fernandez S, Quintana C 1979 The effect of complete biliary obstruction on bile flow and bile acid excretion: postcholestatic choleresis in the rat. J. Lab. Clin. Med. 93: 706-717.
Accatino L, Hono J, Koenig C, Pizarro M, Rodriguez L 1993 Adaptive changes of hepatic bile salt transport in a model of reversible interruption of the enterohepatic circulation in the rat. J. Hepatol. 19: 95-104.
Accatino L, Pizarro M, Solis N, Koenig CS, Vollrath V, Chianale J 1996 Modulation of hepatic content and biliary excretion of P-glycoproteins in hepatocellular and obstructive cholestasis in the rat. J. Hepatol. 25: 349-361. *
Adachi Y, Kamisako T 1996 Intrahepatic cholestasis. Nippon Rinsho 54: 788-793.
Adachi Y, Kamisako T, Okuyama Y, Miya H 1996 Hepatic metabolism and transport of bilirubin and other organic anions. Nippon Rinsho 54: 2276-2290.
Ahmed S, Vo NT, Thalhammer T, Thalhammer F, Gattringer KB, Jager W 2008 Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver. J. Pharm. Pharmacol. 60: 55-62.
Akashi M, Tanaka A, Takikawa H 2006 Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats. Hepatol. Res. 34: 193-198.
Akita H, Suzuki H, Ito K, Kinoshita S, Sato N, Takikawa H, Sugiyama Y 2001 Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump. Biochim. Biophys. Acta 1511: 7-16. *
Akita H, Suzuki H, Sugiyama Y 2002 Sinusoidal efflux of taurocholate correlates with the hepatic expression level of Mrp3. Biochem. Biophys. Res. Commun. 299: 681-687. *
Albrecht C, Elliott JI, Sardini A, Litman T, Stieger B, Meier PJ, Higgins CF 2002 Functional analysis of candidate ABC transporter proteins for sitosterol transport. Biochim. Biophys. Acta 1567: 133-142. *
Alnounou M, Munoz SJ 2006 Nutrition Issues In Gastroenterology, Series #37. Nutrition concerns of the patient with primary biliary cirrhosis or primary sclerosing cholangitis. [http://www.healthsystem.virginia.edu/internet/digestive-health/nutritionarticles/April2006.pdf] Practical Gastroenterology April 2006: 92-100. *
Alpini G, Baiocchi L, Glaser S, Ueno Y, Marzioni M, Francis H, Phinizy JL, Angelico M, Lesage G 2002 Ursodeoxycholate and tauroursodeoxycholate inhibit cholangiocyte growth and secretion of BDL rats through activation of PKC alpha. Hepatology 35: 1041-1052. *
Alpini G, Glaser S, Baiocchi L, Francis H, Xia X, Lesage G 2005 Secretin activation of the apical Na(+)-dependent bile acid transporter is associated with cholehepatic shunting in rats. Hepatology 41: 1037-1045. *
Alpini G, Lenzi R, Zhai WR, Slott PA, Liu MH, Sarkozi L, Tavoloni N 1989 Bile secretory function of intrahepatic biliary epithelium in the rat. Am. J. Physiol. 257: G124-G133.
Alpini G, McGill JM, LaRusso NF 2002 The pathobiology of biliary epithelia. Hepatology 35: 1256-1268. *
Alrefai WA, Gill RK 2007 Bile acid transporters: structure, function, regulation and pathophysiological implications. Pharm. Res. 24: 1803-1823. *
Alrefai WA, Sarwar Z, Tyagi S, Saksena S, Dudeja PK, Gill RK 2005 Cholesterol modulates human intestinal sodium-dependent bile acid transporter. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G978-G985. *
Alvarez L, Jara P, Sanchez-Sabate E, Hierro L, Larrauri J, Diaz MC, Camarena C, De La Vega A, Frauca E, Lopez-Collazo E, Lapunzina P 2004 Reduced hepatic expression of farnesoid X receptor in hereditary cholestasis associated to mutation in ATP8B1. Hum. Mol. Genet. 13: 2451-2460. *
Alvaro D, Benedetti A, Marucci L, Delle Monache M, Monterubbianesi R, Di Cosimo E, Perego L, Macarri G, Glaser S, Le Sage G, Alpini G 2000 The function of alkaline phosphatase in the liver: regulation of intrahepatic biliary epithelium secretory activities in the rat. Hepatology 32: 174-184. *
Ananthanarayanan M, Balasubramanian N, Makishima M, Mangelsdorf DJ, Suchy FJ 2001 Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J. Biol. Chem. 276: 28857-28865. *
Ananthanarayanan M, Li S, Balasubramaniyan N, Suchy FJ, Walsh MJ 2004 Ligand-dependent activation of the farnesoid-X-receptor directs arginine methylation of histone H3 by CARM1. J. Biol. Chem. 279: 54348-54357. *
Andrejko KM, Raj NR, Kim PK, Cereda M, Deutschman CS 2008 IL-6 modulates sepsis-induced decreases in transcription of hepatic organic anion and bile acid transporters. Shock 29: 490-496.
Anelli PL, Lattuada L, Lorusso V, Lux G, Morisetti A, Morosini P, Serleti M, Uggeri F 2004 Conjugates of gadolinium complexes to bile acids as hepatocyte-directed contrast agents for magnetic resonance imaging. J. Med. Chem. 47: 3629-3641. *
Angelin B, Eriksson M, Parini P, Rudling M 2004 Bile acids and lipoproteins. Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 31. June 18-19. *
Annaba F, Sarwar Z, Kumar P, Saksena S, Turner JR, Dudeja PK, Gill RK, Alrefai WA 2008 Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. Am. J. Physiol. Gastrointest. Liver Physiol. 294: G489-G497. *
Anosova NG, Chabot S, Shreedhar V, Borawski JA, Dickinson BL, Neutra MR 2008 Cholera toxin, E. coli heat-labile toxin, and non-toxic derivatives induce dendritic cell migration into the follicle-associated epithelium of Peyer's patches. Mucosal Immunol. 1: 59-67.
Anwer MS 2004 Cellular regulation of hepatic bile acid transport in health and cholestasis. Hepatology 39: 581-590. *
Anwer MS, Ananthanarayanan M, Suchy FJ 2006 Role of Ntcp phosphorylation in cAMP-mediated stimulation of hepatic bile acid uptake. Falk Symposium 155. XIII FALK LIVER WEEK (Part I) XIX International Bile Acid Meeting. Bile Acids: Biological Actions and Clinical Relevance, October 6 - 7, 2006 Freiburg (Germany), p. 29. *
Aoki T 2005 Genetic disorders of copper transport--diagnosis and new treatment for the patients of Wilson's disease. No To Hattatsu 37: 99-109.
Arrese M, Accatino L 2002 From blood to bile: recent advances in hepatobiliary transport. Ann. Hepatol. 1: 64-71. *
Arrese M, Ananthananarayanan M, Suchy FJ 1998 Hepatobiliary transport: molecular mechanisms of development and cholestasis. Pediatr. Res. 44: 141-147.
Arrese M, Ananthanarayanan M 2004 The bile salt export pump: molecular properties, function and regulation. Pflugers Arch. 449: 123-131. *
Arrese M, Macias RI, Briz O, Perez MJ, Marin JJ 2008 Molecular pathogenesis of intrahepatic cholestasis of pregnancy. Expert Rev. Mol. Med. 10: e9.
Arrese M, Reyes H 2006 Intrahepatic cholestasis of pregnancy: a past and present riddle. Ann. Hepatol. 5: 202-205. *
Arrese M, Trauner M 2003 Molecular aspects of bile formation and cholestasis. Trends Mol. Med. 9: 558-564. *
Arrese M, Trauner M, Ananthanarayanan M, Pizarro M, Solis N, Accatino L, Soroka C, Boyer JL, Karpen SJ, Miquel JF, Suchy FJ 2003 Down-regulation of the Na+/taurocholate cotransporting polypeptide during pregnancy in the rat. J. Hepatol. 38: 148-155. *
Arundel C, Lewis JH 2007 Drug-induced liver disease in 2006. Curr. Opin. Gastroenterol. 23: 244-254.
Asamoto Y, Tazuma S, Ochi H, Chayama K, Suzuki H 2001 Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function. Biochem. J. 359: 605-610. *
Assaraf YG 2006 The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis. Drug Resist. Updat. 9: 227-246.
Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD 2004 Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J. Biol. Chem. 279: 22250-22257. *
Audard V, Grimber G, Elie C, Radenen B, Audebourg A, Letourneur F, Soubrane O, Vacher-Lavenu MC, Perret C, Cavard C, Terris B 2007 Cholestasis is a marker for hepatocellular carcinomas displaying beta-catenin mutations. J. Pathol. 212: 345-352. *
Augustine LM, Markelewicz RJ Jr, Boekelheide K, Cherrington NJ 2005 Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier. Drug Metab. Dispos. 33: 182-189. *
Azer SA 2004 Do recommended textbooks contain adequate information about bile salt transporters for medical students? Adv. Physiol. Educ. 28: 36-43. *
Azer SA 2005 A multimedia CD-ROM tool to improve student understanding of bile salts and bilirubin metabolism: evaluation of its use in a medical hybrid PBL course. Adv. Physiol. Educ. 29: 40-50. *
Azer SA, Stacey NH 1996 Current concepts of hepatic uptake, intracellular transport and biliary secretion of bile acids: physiological basis and pathophysiological changes in cholestatic liver dysfunction. J. Gastroenterol. Hepatol. 11: 396-407.
Azzaroli F, Mennone A, Feletti V, Simoni P, Baglivo E, Montagnani M, Rizzo N, Pelusi G, DE Aloysio D, Lodato F, Festi D, Colecchia A, Roda E, Boyer JL, Mazzella G 2007 Clinical trial: modulation of human placental multidrug resistance proteins in cholestasis of pregnancy by ursodeoxycholic acid. Aliment. Pharmacol. Ther. 26: 1139-1146. *
Bahar RJ, Stolz A 1999 Bile acid transport. Gastroenterol. Clin. North Am. 28: 27-58.
Baier PK, Hempel S, Waldvogel B, Baumgartner U 2006 Zonation of hepatic bile salt transporters. Dig. Dis. Sci. 51: 587-593. *
Bajor A, Kilander A, Galman C, Rudling M, Ung KA 2006 Budesonide treatment is associated with increased bile acid absorption in collagenous colitis. Aliment. Pharmacol. Ther. 24: 1643-1649. *
Balakrishnan A, Polli JE 2006 Apical sodium dependent bile acid transporter (ASBT, SLC10A2): a potential prodrug target. Mol. Pharm. 3: 223-230. *
Balakrishnan A, Sussman DJ, Polli JE 2005 Development of stably transfected monolayer overexpressing the human apical sodium-dependent bile acid transporter (hASBT). Pharm. Res. 22: 1269-1280. *
Balakrishnan A, Wring SA, Coop A, Polli JE 2006 Influence of charge and steric bulk in the C-24 region on the interaction of bile acids with human apical sodium-dependent bile acid transporter. Mol. Pharm. 3: 282-292. *
Balakrishnan A, Wring SA, Polli JE 2006 Interaction of native bile acids with human apical sodium-dependent bile acid transporter (hASBT): influence of steroidal hydroxylation pattern and C-24 conjugation. Pharm. Res. 23: 1451-1459. *
Balasubramaniyan N, Shahid M, Suchy FJ, Ananthanarayanan M 2005 Multiple mechanisms of ontogenic regulation of nuclear receptors during rat liver development. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G251-G260. *
Balesaria S, Pell RJ, Abbott LJ, Tasleem A, Chavele KM, Barley NF, Khair U, Simon A, Moriarty KJ, Brydon WG, Walters JR 2008 Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. Eur. J. Gastroenterol. Hepatol. 20: 413-422.
Balistreri WF 1997 Bile acid therapy in pediatric hepatobiliary disease: the role of ursodeoxycholic acid. J. Pediatr. Gastroenterol. Nutr. 24: 573-589.
Balistreri WF 2003 Genetic liver disease. 54th Annual Meeting of the American Association for the Study of Liver Diseases.
Balkova K, Gbelska Y 2007 ABC transporter proteins in multidrug resistance of microorganisms. Epidemiol. Mikrobiol. Imunol. 56: 129-139.
Ballatori N 2005 Biology of a novel organic solute and steroid transporter, OST{alpha}-OST{beta}. Exp. Biol. Med. (Maywood) 230: 689-698. *
Ballatori N, Christian WV, Lee JY, Dawson PA, Soroka CJ, Boyer JL, Madejczyk MS, Li N 2005 OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology 42: 1270-1279. *
Ballatori N, Fang F, Christian WV, Li N, Hammond CL 2008 Ost{alpha}-Ost{beta} is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G179-G186. *
Ballatori N, Hammond CL, Cunningham JB, Krance SM, Marchan R 2005 Molecular mechanisms of reduced glutathione transport: role of the MRP/CFTR/ABCC and OATP/SLC21A families of membrane proteins. Toxicol. Appl. Pharmacol. 204: 238-255. *
Ballatori N, Henson JH, Seward DJ, Cai SY, Runnegar M, Fricker G, Miller DS, Boyer JL 2006 Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis. Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 144: 167-179. *
Ballatori N, Rebbeor JF 1998 Roles of MRP2 and oatp1 in hepatocellular export of reduced glutathione. Semin. Liver Dis. 18: 377-387.
Ballatori N, Rebbeor JF, Connolly GC, Seward DJ, Lenth BE, Henson JH, Sundaram P, Boyer JL 2000 Bile salt excretion in skate liver is mediated by a functional analog of Bsep/Spgp, the bile salt export pump. Am. J. Physiol. Gastrointest. Liver Physiol. 278: G57-G63. *
Ballestero MR, Monte MJ, Briz O, Jimenez F, Gonzalez-San Martin F, Marin JJ 2006 Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps. Biochem. Pharmacol. 72: 729-738. *
Banerjee A, Hussainzada N, Khandelwal A, Swaan PW 2008 Electrostatic and potential cation-pi forces may guide the interaction of extracellular loop III with Na+ and bile acids for human apical Na+-dependent bile acid transporter. Biochem. J. 410: 391-400. *
Banerjee A, Ray A, Chang C, Swaan PW 2005 Site-directed mutagenesis and use of bile acid-MTS conjugates to probe the role of cysteines in the human apical sodium-dependent bile acid transporter (SLC10A2). Biochemistry 44: 8908-8917. *
Barbara G, Stanghellini V, Brandi G, Cremon C, Di Nardo G, De Giorgio R, Corinaldesi R 2005 Interactions between commensal bacteria and gut sensorimotor function in health and disease. Am. J. Gastroenterol. 100: 2560-2568. *
Barbier O, Torra IP, Duguay Y, Blanquart C, Fruchart JC, Glineur C, Staels B 2002 Pleiotropic actions of peroxisome proliferator-activated receptors in lipid metabolism and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 22: 717-726. *
Barbier O, Torra IP, Sirvent A, Claudel T, Blanquart C, Duran-Sandoval D, Kuipers F, Kosykh V, Fruchart JC, Staels B 2003 FXR induces the UGT2B4 enzyme in hepatocytes: a potential mechanism of negative feedback control of FXR activity. Gastroenterology 124: 1926-1940. *
Barnes DS 2002 Intrahepatic cholestatic liver disease. http://www.clevelandclinicmeded.com/diseasemanagement/gastro/intrahepatic/intrahepatic1.htm.
Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken M, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE 2007 Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases. Drug Metab. Dispos. 35: 1963-1969. *
Barth A, Braun J, Muller D 2006 Bile acid transport and metabolism in rat liver slices. Exp. Toxicol. Pathol. 57: 313-319.
Barth A, Braun J, Muller D 2006 Influence of verapamil and cyclosporin A on bile acid metabolism and transport in rat liver slices. Exp. Toxicol. Pathol. 58: 31-37. *
Barth A, Rost M, Kindt A, Peiker G 2005 Serum bile acid profile in women during pregnancy and childbed. Exp. Clin. Endocrinol. Diabetes 113: 372-375.
Batta AK, Tint GS, Xu G, Shefer S, Salen G 1998 Synthesis and intestinal metabolism of ursodeoxycholic acid conjugate with an antiinflammatory agent, 5-aminosalicylic acid. J. Lipid Res. 39: 1641-1646. *
Beath SV 2003 Hepatic function and physiology in the newborn. Semin. Neonatol. 8: 337-346.
Behar J, Corazziari E, Guelrud M, Hogan W, Sherman S, Toouli J 2006 Functional disorders of gallbladder and sphincter of oddi. Gastroenterology 130: 1498-1509. *
Beilke LD, Besselsen DG, Cheng Q, Kulkarni S, Slitt AL, Cherrington NJ 2008 Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis. Toxicol. Sci. 102: 196-204. *
Benedetti A, Alvaro D, Bassotti C, Gigliozzi A, Ferretti G, La Rosa T, Di Sario 1997 Cytotoxicity of bile salts against biliary epithelium: a study in isolated bile ductule fragments and isolated perfused rat liver. Hepatology 26: 9-21. *
Berard AM, Dumon MF, Darmon M 2004 Dietary fish oil up-regulates cholesterol 7alpha-hydroxylase mRNA in mouse liver leading to an increase in bile acid and cholesterol excretion. FEBS Lett. 559: 125-128. *
Bergasa NV 2005 The pruritus of cholestasis. J. Hepatol. 43: 1078-1088. *
Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ 2004 Primary biliary cirrhosis: report of a focus study group. Hepatology 40: 1013-1020. *
Bergheim I, Harsch S, Mueller O, Schimmel S, Fritz P, Stange EF 2006 Apical sodium bile acid transporter and ileal lipid binding protein in gallstone carriers. J. Lipid Res. 47: 42-50. *
Bergman E, Forsell P, Tevell A, Persson EM, Hedeland M, Bondesson U, Knutson L, Lennernas H 2006 Biliary secretion of rosuvastatin and bile acids in humans during the absorption phase. Eur. J. Pharm. Sci. 29: 205-214. *
Bertrams A, Ziegler K 1991 Hepatocellular uptake of peptides by bile acid transporters: relationship of carrier-mediated transport of linear peptides with renin-inhibiting activity to multispecific bile acid carriers. Biochim. Biophys. Acta 1091: 337-348.
Besnard P, Landrier JF, Grober J, Niot I 2004 Is the ileal bile acid-binding protein (I-BABP) gene involved in cholesterol homeostasis? Med. Sci. (Paris) 20: 73-77.
Beuers U 2003 Mechanisms of action of ursodeoxycholic acid in cholestasis. Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper�s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 49-50. October 15-16. *
Beuers U 2006 Drug insight: mechanisms and sites of action of ursodeoxycholic acid in cholestasis. Nat. Clin. Pract. Gastroenterol. Hepatol. 3: 318-328. *
Beuers U 2006 Mechanisms of action of ursodeoxycholic acid for treatment of primary sclerosing cholangitis. Falk Workshop "Primary Sclerosing Cholangitis: Complications and Consequences", Moscow (Russia), June 11, 2006, p. 12. *
Beuers U, Bilzer M, Chittattu A, Kullak-Ublick GA, Keppler D, Paumgartner G, Dombrowski F 2001 Tauroursodeoxycholic acid inserts the apical conjugate export pump, Mrp2, into canalicular membranes and stimulates organic anion secretion by protein kinase C-dependent mechanisms in cholestatic rat liver. Hepatology 33: 1206-1216. *
Beukeveld GJ, In 't Veld G, Havinga R, Groen AK, Wolthers BG, Kuipers F 1996 Relationship between biliary lipid and protoporphyrin secretion; potential role of mdr2 P-glycoprotein in hepatobiliary organic anion transport. J. Hepatol. 24: 343-352. *
Bi YA, Kazolias DC, Duignan DB 2006 Use of cryopreserved human hepatocytes in sandwich-culture to measure hepatobiliary transport. Drug Metab. Dispos. 34: 1658-1665. *
Bijvelds MJ, Jorna H, Verkade HJ, Bot AG, Hofmann F, Agellon LB, Sinaasappel M, de Jonge HR 2005 Activation of CFTR by ASBT-mediated bile salt absorption. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G870-G879. *
Bird NC, Ooi RC, Luo XY, Chin SB, Johnson AG 2006 Investigation of the functional three-dimensional anatomy of the human cystic duct: a single helix? Clin. Anat. 19: 528-534.
Bishop-Bailey D, Walsh DT, Warner TD 2004 Expression and activation of the farnesoid X receptor in the vasculature. Proc. Natl. Acad. Sci. U.S.A. 101: 3668-3673. *
Bjornsson E, Chapman RW 2003 Sclerosing cholangitis. Curr. Opin. Gastroenterol. 19: 270-275.
Bloks VW, Bakker-Van Waarde WM, Verkade HJ, Kema IP, Wolters H, Vink E, Groen AK, Kuipers F 2004 Down-regulation of hepatic and intestinal Abcg5 and Abcg8 expression associated with altered sterol fluxes in rats with streptozotocin-induced diabetes. Diabetologia 47: 104-112. *
Bloomer J, Wang Y, Singhal A, Risheg H 2005 Molecular studies of liver disease in erythropoietic protoporphyria. J. Clin. Gastroenterol. 39: S167-S175.
Bochkis IM, Rubins NE, White P, Furth EE, Friedman JR, Kaestner KH 2008 Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat. Med. Jul 27 [Epub ahead of print]. *
Bode KA, Donner MG, Leier I, Keppler D 2002 Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate. Biochem. Pharmacol. 64: 151-158. *
Bodo A, Bakos E, Szeri F, Varadi A, Sarkadi B 2003 Differential modulation of the human liver conjugate transporters MRP2 and MRP3 by bile acids and organic anions. J. Biol. Chem. 278: 23529-23537. *
Bogert PT, LaRusso NF 2007 Cholangiocyte biology. Curr. Opin. Gastroenterol. 23: 299-305.
Bohme M, Jedlitschky G, Leier I, Buchler M, Keppler D 1994 ATP-dependent export pumps and their inhibition by cyclosporins. Adv. Enzyme Regul. 34: 371-380.
Bohme M, Muller M, Leier I, Jedlitschky G, Keppler D 1994 Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver. Gastroenterology 107: 255-265.
Bolder U, Jeschke MG, Landmann L, Wolf F, de Sousa C, Schlitt HJ, Przkora R 2006 Heat stress enhances recovery of hepatocyte bile acid and organic anion transporters in endotoxemic rats by multiple mechanisms. Cell Stress Chaperones 11: 89-100. *
Bolder U, Schmidt A, Landmann L, Kidder V, Tange S, Jauch KW 2002 Heat stress prevents impairment of bile acid transport in endotoxemic rats by a posttranscriptional mechanism. Gastroenterology 122: 963-973. *
Bolder U, Thasler WE, Hofmann AF, Jauch KW 1998 Hepatocellular transport of bile acids and organic anions in infection and SIRS--evidence for different mechanisms for regulating membrane transport proteins. Langenbecks Arch. Chir. Suppl. Kongressbd. 115 (Suppl. I): 391-396.
Bolder U, Ton-Nu HT, Schteingart CD, Frick E, Hofmann AF 1997 Hepatocyte transport of bile acids and organic anions in endotoxemic rats: impaired uptake and secretion. Gastroenterology 112: 214-225. *
Bolder U, Trang NV, Hagey LR, Schteingart CD, Ton-Nu HT, Cerre C, Elferink RP, Hofmann AF 1999 Sulindac is excreted into bile by a canalicular bile salt pump and undergoes a cholehepatic circulation in rats. Gastroenterology 117: 962-971. *
Borgognone M, Perez LM, Basiglio CL, Ochoa JE, Roma MG 2005 Signaling modulation of bile salt-induced necrosis in isolated rat hepatocytes. Toxicol. Sci. 83: 114-125. *
Borst P, de Wolf C, van de Wetering K 2007 Multidrug resistance-associated proteins 3, 4, and 5. Pflugers Arch. 453: 661-673. *
Borst P, Oude Elferink RP 2002 Mammalian ABC transporters in health and disease. Annu. Rev. Biochem. 71: 537-592. *
Bosse T, Piaseckyj CM, Burghard E, Fialkovich JJ, Rajagopal S, Pu WT, Krasinski SD 2006 Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol. Cell. Biol. 26: 9060-9070. *
Boucherie S, Koukoui O, Nicolas V, Combettes L 2005 Cholestatic bile acids inhibit gap junction permeability in rat hepatocyte couplets and normal rat cholangiocytes. J. Hepatol. 42: 244-251 (2005). *
Boulias K, Katrakili N, Bamberg K, Underhill P, Greenfield A, Talianidis I 2005 Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP. EMBO J. 24: 2624-2633. *
Bouscarel B, Kroll SD, Fromm H 1999 Signal transduction and hepatocellular bile acid transport: cross talk between bile acids and second messengers. Gastroenterology 117: 433-452. *
Boyer JL 1996 Bile duct epithelium: frontiers in transport physiology. Am. J. Physiol. 270: G1-G5.
Boyer JL 2005 Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease? Gastroenterology 129: 735-740. *
Boyer JL 2007 New perspectives for the treatment of cholestasis: lessons from basic science applied clinically. J. Hepatol. 46: 365-371. *
Boyer JL, Denk G, Bohan A, Chen WS, Soroka C, Denson L 2004 Adaptive regulation of bile salt transporters in cholestasis. Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 46-47. June 18-19. *
Boyer JL, Ng OC, Ananthanarayanan M, Hofmann AF, Schteingart CD, Hagenbuch B, Stieger B, Meier PJ 1994 Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells. Am. J. Physiol. 266: G382-G387.
Boyer JL, Trauner M, Mennone A, Soroka CJ, Cai SY, Moustafa T, Zollner G, Lee JY, Ballatori N 2006 Up-regulation of a basolateral FXR-dependent bile acid efflux transporter, OST{alpha}-OST{beta}, in cholestasis in humans and rodents. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1124-G1130. *
Bradford W, Allen D, Shelburne J, Spock A 1983 Hepatic parenchymal cells in cystic fibrosis: ultrastructural evidence for abnormal intracellular transport. Pediatr. Pathol. 1: 269-279.
Brandoni A, Anzai N, Kanai Y, Endou H, Torres AM 2006 Renal elimination of p-aminohippurate (PAH) in response to three days of biliary obstruction in the rat. The role of OAT1 and OAT3. Biochim. Biophys. Acta 1762: 673-682. *
Breen CM, Sykes DB, Baehr C, Fricker G, Miller DS 2004 Fluorescien-methotrexate transport in rat choroid plexus analyzed using confocal microscopy. Am. J. Physiol. Renal Physiol. 287: F562-F569. *
Briz O, Macias RI, Perez MJ, Serrano MA, Marin JJ 2006 Excretion of fetal biliverdin by the rat placenta-maternal liver tandem. Am. J. Physiol. Regul. Integr. Comp. Physiol. 290: R749-R756. *
Briz O, Romero MR, Martinez-Becerra P, Macias RI, Perez MJ, Jimenez F, San Martin FG, Marin JJ 2006 OATP8/1B3-mediated cotransport of bile acids and glutathione: an export pathway for organic anions from hepatocytes? J. Biol. Chem. 281: 30326-30335. *
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