• Aalberse RC, Stapel SO, Schuurman J, Rispens T. Immunoglobulin G4: an odd antibody. Clin. Exp. Allergy 39: 469-477 (2009). *

• Abu-Ghefreh AA, Canatan H, Ezeamuzie CI. In vitro and in vivo anti-inflammatory effects of andrographolide. Int. Immunopharmacol. 9: 313-318 (2009).

• Acha-Orbea H. Limited heterogeneity of autoantigens and T cells in autoimmune diseases? Res. Immunol. 142: 487-490 (1991).

• Adisakwattana P, Saunders SP, Nel HJ, Fallon PG. Helminth-derived immunomodulatory molecules. Adv. Exp. Med. Biol. 666: 95-107 (2009).

• Afzali B, Lombardi G, Lechler RI, Lord GM. The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease. Clin. Exp. Immunol. 148: 32-46 (2007). *

• Agarwal R, Aggarwal AN, Gupta D, Bal A, Das A. Case report: a rare cause of miliary nodules - allergic bronchopulmonary aspergillosis. Br. J. Radiol. 82: e151-e154 (2009).

• Agarwal R, Aggarwal AN, Gupta N, Gupta D. A rare cause of acute respiratory failure - allergic bronchopulmonary aspergillosis. Mycoses Dec 21 [Epub ahead of print] (2009).

• Agarwal R, Singh N, Aggarwal AN. An unusual association between Mycobacterium tuberculosis and Aspergillus fumigatus. Monaldi Arch. Chest Dis. 69: 32-34 (2008).

• Agarwal R, Srinivas R, Jindal SK. Allergic bronchopulmonary aspergillosis complicating chronic obstructive pulmonary disease. Mycoses 51: 83-85 (2008).

• Aghamohammadi A, Cheraghi T, Gharagozlou M, Movahedi M, Rezaei N, Yeganeh M, Parvaneh N, Abolhassani H, Pourpak Z, Moin M. IgA deficiency: correlation between clinical and immunological phenotypes. J. Clin. Immunol. 29: 130-136 (2009). *

• Aguilera-Aguirre L, Bacsi A, Saavedra-Molina A, Kurosky A, Sur S, Boldogh I. Mitochondrial dysfunction increases allergic airway inflammation. J. Immunol. 183: 5379-5387 (2009).

• Ahn SC, Kim GY, Kim JH, Baik SW, Han MK, Lee HJ, Moon DO, Lee CM, Kang JH, Kim BH, Oh YH, Park YM. Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB. Biochem. Biophys. Res. Commun. 313: 148-155 (2004). *

• Aiba S, Tagami H. Dendritic cells play a crucial role in innate immunity to simple chemicals. J. Investig. Dermatol. Symp. Proc. 4: 158-163 (1999). *

• Akahoshi M, Ishihara M, Namba K, Kitaichi N, Ando Y, Takenaka S, Ishida T, Ohno S, Mizuki N, Nakashima H, Shirakawa T. Mutation screening of the CARD15 gene in sarcoidosis. Tissue Antigens 71: 564-567 (2008). *

• Akahoshi M, Ishihara M, Remus N, Uno K, Miyake K, Hirota T, Nakashima K, Matsuda A, Kanda M, Enomoto T, Ohno S, Nakashima H, Casanova JL, Hopkin JM, Tamari M, Mao XQ, Shirakawa T. Association between IFNA genotype and the risk of sarcoidosis. Hum. Genet. 114: 503-509 (2004). *

• Akahoshi M, Nakashima H, Shirakawa T. Roles of genetic variations in signalling/immunoregulatory molecules in susceptibility to systemic lupus erythematosus. Semin. Immunol. 18: 224-229 (2006). *

• Akbari O. The role of iNKT cells in development of bronchial asthma: a translational approach from animal models to human. Allergy 61: 962-968 (2006). *

• Akbari O, Faul JL, Hoyte EG, Berry GJ, Wahlstrom J, Kronenberg M, DeKruyff RH, Umetsu DT. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N. Engl. J. Med. 354: 1117-1129 (2006). *

• Akbay E, Arbag H, Uyar Y, Ozturk K. Oxidative stress and antioxidant factors in pathophysiology of allergic rhinitis. Kulak. Burun. Bogaz. Ihtis. Derg. 17: 189-196 (2007).

• Akdis M. Immune tolerance in allergy. Curr. Opin. Immunol. 21: 700-707 (2009).

• Akdis M, Akdis CA. Therapeutic manipulation of immune tolerance in allergic disease. Nat. Rev. Drug Discov. 8: 645-660 (2009).

• Akdis M, Akdis CA. Mechanisms of allergen-specific immunotherapy. J. Allergy Clin. Immunol. 119: 780-791 (2007). *

• Akimoto M, Mishra K, Lim KT, Tani N, Hisanaga SI, Katagiri T, Elson A, Mizuno K, Yakura H. Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses. Scand. J. Immunol. 69: 401-411 (2009). *

• Akobeng AK. Crohn's disease: current treatment options. Arch. Dis. Child. 93: 787-792 (2008).

• Al Senaidy AM. Serum vitamin A and beta-carotene levels in children with asthma. J. Asthma 46: 699-702 (2009).

• Al-Abdulhadi SA, Al-Rabia MW. Association and preferential transmission of the CCR2V64I polymorphism with absence of asthma in high-risk families. Saudi Med. J. 29: 1711-1718 (2008).

• Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J. Immunol. 162: 494-502 (1999). *

• Albanesi C, Scarponi C, Cavani A, Federici M, Nasorri F, Girolomoni G. Interleukin-17 is produced by both Th1 and Th2 lymphocytes, and modulates interferon-gamma- and interleukin-4-induced activation of human keratinocytes. J. Invest. Dermatol. 115: 81-87 (2000). *

• Albert D, Clarkin C, Komoroski J, Brensinger CM, Berlin JA. Wegener's granulomatosis: possible role of environmental agents in its pathogenesis. Arthritis Rheum. 51: 656-664 (2004). *

• Albertella MR, Jones H, Thomson W, Olavesen MG, Campbell RD. Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). Genomics 36: 240-251 (1996). *

• Alexis NE, Brickey WJ, Lay JC, Wang Y, Roubey RA, Ting JP, Peden DB. Development of an inhaled endotoxin challenge protocol for characterizing evoked cell surface phenotype and genomic responses of airway cells in allergic individuals. Ann. Allergy Asthma Immunol. 100: 206-215 (2008).

• Ali FR, Larche M. Peptide-based immunotherapy: a novel strategy for allergic disease. Expert Rev. Vaccines 4: 881-889 (2005).

• Allakhverdi Z, Comeau MR, Jessup HK, Yoon BR, Brewer A, Chartier S, Paquette N, Ziegler SF, Sarfati M, Delespesse G. Thymic stromal lymphopoietin is released by human epithelial cells in response to microbes, trauma, or inflammation and potently activates mast cells. J. Exp. Med. 204: 253-258 (2007). *

• Alli R, Nguyen P, Geiger TL. Retrogenic modeling of experimental allergic encephalomyelitis associates T cell frequency but not TCR functional affinity with pathogenicity. J. Immunol. 181: 136-145 (2008). *

• Almqvist C, Garden F, Xuan W, Mihrshahi S, Leeder SR, Oddy W, Webb K, Marks GB; for the CAPS team. Omega-3 and omega-6 fatty acid exposure from early life does not affect atopy and asthma at age 5 years. J. Allergy Clin. Immunol. 119: 1438-1444 (2007). *

• Alonso A, Hernan MA, Ascherio A. Allergy, family history of autoimmune diseases, and the risk of multiple sclerosis. Acta Neurol. Scand. 117: 15-20 (2008). *

• Alonso A, Jick SS, Hernan MA. Allergy, histamine 1 receptor blockers, and the risk of multiple sclerosis. Neurology 66: 572-575 (2006).

• Alvarez D, Arkinson JL, Sun J, Fattouh R, Walker T, Jordana M. Th2 differentiation in distinct lymph nodes influences the site of mucosal Th2 immune-inflammatory responses. J. Immunol. 179: 3287-3296 (2007). *

• Amerio P, Frezzolini A, Feliciani C, Verdolini R, Teofoli P, De Pita O, Puddu P. Eotaxins and CCR3 receptor in inflammatory and allergic skin diseases: therapeutical implications. Curr. Drug Targets Inflamm. Allergy 2: 81-94 (2003).

• Amin R, Dupuis A, Aaron SD, Ratjen F. The effect of chronic infection with Aspergillus fumigatus on lung function and hospitalization in cystic fibrosis patients. Chest Jun 30 [Epub ahead of print] (2009).

• Ammendola M, Pietropolli A, Saccucci P, Piccione E, Bottini E, Gloria-Bottini F. Acid phosphatase locus 1 genetic polymorphism, endometriosis, and allergy. Fertil. Steril. 90: 1203-1205 (2008).

• Amoli MM, Hand S, Hajeer AH, Jones KP, Rolf S, Sting C, Davies BH, Ollier WE. Polymorphism in the STAT6 gene encodes risk for nut allergy. Genes Immun. 3: 220-224 (2002). *

• Amoudruz P, Minang JT, Sundstrom Y, Nilsson C, Lilja G, Troye-Blomberg M, Sverremark-Ekstrom E. Pregnancy, but not the allergic status, influences spontaneous and induced interleukin-1beta (IL-1beta), IL-6, IL-10 and IL-12 responses. Immunology 119: 18-26 (2006). *

• Anandan C, Nurmatov U, Sheikh A. Omega 3 and 6 oils for primary prevention of allergic disease: systematic review and meta-analysis. Allergy 64: 840-848 (2009). *

• Andrade MC, Menezes JS, Cassali GD, Martins-Filho OA, Cara DC, Faria AM. Alcohol-induced gastritis prevents oral tolerance induction in mice. Clin. Exp. Immunol. 146: 312-322 (2006). *

• Andre J. Artificial nails and psoriasis. J. Cosmet. Dermatol. 4: 103-106 (2005).

• Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling. Nat. Immunol. Feb 14 [Epub ahead of print] (2010). *

• Angkasekwinai P, Park H, Wang YH, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C. Interleukin 25 promotes the initiation of proallergic type 2 responses. J. Exp. Med. 204: 1509-1517 (2007). *

• Annunziato F, Romagnani S. Heterogeneity of human effector CD4+ T cells. Arthritis Res. Ther. 11: 257 (2009).

• Ano H, Matsumoto T, Suetake T, Nagai T, Tamura Y, Takamatsu I, Iwasaki T, Matsuoka H, Sasada S, Tetsumoto S, Tsuyuguchi I, Kusunoki Y, Takashima T. Relationship between the isoniazid-resistant mutation katGS315T and the prevalence of MDR-/XDR-TB in Osaka, Japan. Int. J. Tuberc. Lung Dis. 12: 1300-1305 (2008).

• Aoki H, Hisada T, Ishizuka T, Utsugi M, Kawata T, Shimizu Y, Okajima F, Dobashi K, Mori M. Resolvin E1 dampens airway inflammation and hyperresponsiveness in a murine model of asthma. Biochem. Biophys. Res. Commun. 367: 509-515 (2008). *

• Arai T, Kaneko H, Ohnishi H, Matsui E, Fukao T, Kawamoto N, Kasahara K, Kondo N. Hypothermia augments NF-kappaB activity and the production of IL-12 and IFN-gamma. Allergol. Int. 57: 331-338 (2008). *

• Argiriadi MA, Xiang T, Wu C, Ghayur T, Borhani DW. Unusual water-mediated antigenic recognition of the pro-inflammatory cytokine interleukin-18. J. Biol. Chem. 284: 24478-24489 (2009). *

• Arinobu Y, Iwasaki H, Akashi K. Origin of basophils and mast cells. Allergol. Int. 58: 21-28 (2009). *

• Arm JP, Thien FC, Lee TH. Leukotrienes, fish-oil, and asthma. Allergy Proc. 15: 129-134 (1994).

• Armentia A, Arranz E, Hernandez N, Garrote A, Panzani R, Blanco A. Allergy after inhalation and ingestion of cereals involve different allergens in allergic and celiac disease. Recent Pat. Inflamm. Allergy Drug Discov. 2: 45-57 (2008).

• Arnaboldi PM, Behr MJ, Metzger DW. Mucosal B cell deficiency in IgA-/- mice abrogates the development of allergic lung inflammation. J. Immunol. 175: 1276-1285 (2005). *

• Aroeira LS. TCR vaccination in aluminum adjuvant protects against autoimmune encephalomyelitis. Clin. Immunol. 119: 252-260 (2006). *

• Aron Y, Swierczewski E, Lockhart A. A simple and rapid micromethod for genomic DNA extraction from jugal epithelial cells. Application to human lymphocyte antigen typing in one large family of atopic/asthmatic probands. Allergy 49: 788-790 (1994).

• Arruda LK, Santos AB. Immunologic responses to common antigens in helminthic infections and allergic disease. Curr. Opin. Allergy Clin. Immunol. 5: 399-402 (2005).

• Arshad SH, Karmaus W, Kurukulaaratchy R, Sadeghnejad A, Huebner M, Ewart S. Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood. Br. J. Dermatol. 158: 1315-1322 (2008). *

• Asarch A, Barak O, Loo DS, Gottlieb AB. Th17 cells: a new therapeutic target in inflammatory dermatoses. J. Dermatolog. Treat. 19: 318-326 (2008). *

• Ashraf-Benson S, Wall GC, Veach LA. Serum sickness-like reaction associated with efalizumab. Ann. Pharmacother. 43: 383-386 (2009).

• Asquith DL, McInnes IB. Emerging cytokine targets in rheumatoid arthritis. Curr. Opin. Rheumatol. 19: 246-251 (2007). *

• Atalar K, Afzali B, Lord G, Lombardi G. Relative roles of Th1 and Th17 effector cells in allograft rejection. Curr. Opin. Organ Transplant. 14: 23-29 (2009).

• August A, Mueller C, Weaver V, Polanco TA, Walsh ER, Cantorna MT. Nutrients, nuclear receptors, inflammation, immunity lipids, PPAR, and allergic asthma. J. Nutr. 136: 695-699 (2006). *

• Autret-Leca E, Bensouda-Grimaldi L, Jonville-Bera AP, Beau-Salinas F. Pharmacovigilance of vaccines. Arch. Pediatr. 13: 175-180 (2006).

• Averbeck M, Gebhardt C, Emmrich F, Treudler R, Simon JC. Immunologic principles of allergic disease. J. Dtsch. Dermatol. Ges. 5: 1015-1028 (2007).

• Aversano M, Caiazzo P, Iorio G, Ponticiello L, Lagana B, Leccese F. Improvement of chronic idiopathic urticaria with L-thyroxine: a new TSH role in immune response? Allergy 60: 489-493 (2005). *

• Avgeri SG, Matthaiou DK, Dimopoulos G, Grammatikos AP, Falagas ME. Therapeutic options for Burkholderia cepacia infections beyond co-trimoxazole: a systematic review of the clinical evidence. Int. J. Antimicrob. Agents 33: 394-404 (2009). *

• Babinski D, Trawinska-Bartnicka M. Rhinosinusitis in cystic fibrosis: not a simple story. Int. J. Pediatr. Otorhinolaryngol. 72: 619-624 (2008).

• Bach JF. Protective role of infections and vaccinations on autoimmune diseases. J. Autoimmun. 16: 347-353 (2001).

• Bach JF. Six questions about the hygiene hypothesis. Cell. Immunol. 233: 158-161 (2005). *

• Bach JF. Infections and autoimmune diseases. J. Autoimmun. 25: S74-S80 (2005).

• Baert F, De Vos M, Louis E, Vermeire S; Belgian IBD Research Group. Immunogenicity of infliximab: how to handle the problem? Acta Gastroenterol. Belg. 70: 163-170 (2007).

• Baert FJ, Rutgeerts PJ. Medical therapies for ulcerative colitis and Crohn's disease. Curr. Gastroenterol. Rep. 2: 446-450 (2000).

• Bager P, Arnved J, Ronborg S, Wohlfahrt J, Poulsen LK, Westergaard T, Petersen HW, Kristensen B, Thamsborg S, Roepstorff A, Kapel C, Melbye M. Trichuris suis ova therapy for allergic rhinitis: a randomized, double-blind, placebo-controlled clinical trial. J. Allergy Clin. Immunol. Oct 2 [Epub ahead of print] (2009).

• Baguet A, Bix M. Chromatin landscape dynamics of the Il4-Il13 locus during T helper 1 and 2 development. Proc. Natl. Acad. Sci. U.S.A. 101: 11410-11415 (2004). *

• Bahceciler NN, Ozdemir C, Barlan IB. Immunologic aspects of sublingual immunotherapy in the treatment of allergy and asthma. Curr. Med. Chem. 14: 265-269 (2007).

• Bai C, Matsui E, Ohnishi H, Kimata K, Kasahara K, Kaneko H, Kato Z, Fukao T, Kondo N. A novel polymorphism, E254K, in the 5-lipoxygenase gene associated with bronchial asthma. Int. J. Mol. Med. 21: 139-144 (2008). *

• Bai L, Lennon DP, Eaton V, Maier K, Caplan AI, Miller SD, Miller RH. Human bone marrow-derived mesenchymal stem cells induce Th2-polarized immune response and promote endogenous repair in animal models of multiple sclerosis. Glia 57: 1192-1203 (2009).

• Baier G, Asadullah K, Zugel U. The immunological synapse: kinases in T cell signalling as potential drug targets. Immunol. Lett. 105: 3-5 (2006).

• Bailey E, Shaker M. An update on childhood urticaria and angioedema. Curr. Opin. Pediatr. 20: 425-430 (2008).

• Bajor J, Bero T. Diarrhea, from the gastroenterologist's point of view. Orv. Hetil. 150: 1655-1661 (2009).

• Bak H, Lee WJ, Lee YW, Chang SE, Choi JH, Kim MN, Kim BJ, Choi YS, Suh HS. Expression of neuropeptides and their degrading enzymes in ACD. Clin. Exp. Dermatol. Dec 16 [Epub ahead of print] (2009). *

• Bala G, Swincow G, Rytarowska A, Czerwionka-Szaflarska M. Non-specific inflammatory bowel disease or allergic colitis in small children - what is the final diagnosis? Med. Wieku. Rozwoj. X: 475-482 (2006).

• Ballantyne SJ, Barlow JL, Jolin HE, Nath P, Williams AS, Chung KF, Sturton G, Wong SH, McKenzie AN. Blocking IL-25 prevents airway hyperresponsiveness in allergic asthma. J. Allergy Clin. Immunol. 120: 1324-1331 (2007). *

• Ballow M. Biologic immune modifiers: trials and tribulations - are we there yet? J. Allergy Clin. Immunol. 118: 1209-1215 (2006). *

• Bang UC, Nielsen AM. The use of adalimumab in severe fistulising Crohn's disease - three cases. Ugeskr. Laeger. 170: 2256 (2008).

• Bangert C, Friedl J, Stary G, Stingl G, Kopp T. Immunopathologic features of allergic contact dermatitis in humans: participation of plasmacytoid dendritic cells in the pathogenesis of the disease? J. Invest. Dermatol. 121: 1409-1418 (2003). *

• Banno T, Gazel A, Blumenberg M. Effects of tumor necrosis factor-alpha (TNFalpha) in epidermal keratinocytes revealed using global transcriptional profiling. J. Biol. Chem. 279: 32633-32642 (2004). *

• Banovcin P, Havlicekova Z, Jesenak M, Nosal S, Durdík P, Ciljakova M, Mikler J. Severe quadriparesis caused by wasp sting. Turk. J. Pediatr. 51: 485-488 (2009).

• Bansal G, Xie Z, Rao S, Nocka KH, Druey KM. Suppression of immunoglobulin E-mediated allergic responses by regulator of G protein signaling 13. Nat. Immunol. 9: 73-80 (2008). *

• Baranyi U, Pilat N, Gattringer M, Wekerle T. A chimerism-based approach to induce tolerance in IgE-mediated allergy. Crit. Rev. Immunol. 29: 379-397 (2009).

• Barberis L, Hirsch E. Targeting phosphoinositide 3-kinase gamma to fight inflammation and more. Thromb. Haemost. 99: 279-285 (2008).

• Bardin T. Current management of gout in patients unresponsive or allergic to allopurinol. Joint Bone Spine 71: 481-485 (2004).

• Baricordi OR, Stignani M, Melchiorri L, Rizzo R. HLA-G and inflammatory diseases. Inflamm. Allergy Drug Targets 7: 67-74 (2008).

• Barnes J, Anderson LA, Gibbons S, Phillipson JD. Echinacea species (Echinacea angustifolia (DC.) Hell., Echinacea pallida (Nutt.) Nutt., Echinacea purpurea (L.) Moench): a review of their chemistry, pharmacology and clinical properties. J. Pharm. Pharmacol. 57: 929-954 (2005).

• Barnes KC, Grant AV, Baltadzhieva D, Zhang S, Berg T, Shao L, Zambelli-Weiner A, Anderson W, Nelsen A, Pillai S, Yarnall DP, Dienger K, Ingersoll RG, Scott AF, Fallin MD, Mathias RA, Beaty TH, Garcia JG, Wills-Karp M. Variants in the gene encoding C3 are associated with asthma and related phenotypes among African Caribbean families. Genes Immun. 7: 27-35 (2006). *

• Barrett NA, Austen KF. Innate cells and T helper 2 cell immunity in airway inflammation. Immunity 31: 425-437 (2009). *

• Barrett NA, Maekawa A, Rahman OM, Austen KF, Kanaoka Y. Dectin-2 recognition of house dust mite triggers cysteinyl leukotriene generation by dendritic cells. J. Immunol. 182: 1119-1128 (2009).

• Barton RC, Hobson RP, Denton M, Peckham D, Brownlee K, Conway S, Kerr MA. Serologic diagnosis of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis through the detection of immunoglobulin G to Aspergillus fumigatus. Diagn. Microbiol. Infect. Dis. 62: 287-291 (2008).

• Bartunkova J, Kayserova J, Shoenfeld Y. Allergy and autoimmunity: parallels and dissimilarity. The Yin and Yang of immunopathology. Autoimmun. Rev. 8: 302-308 (2009).

• Basehore MJ, Howard TD, Lange LA, Moore WC, Hawkins GA, Marshik PL, Harkins MS, Meyers DA, Bleecker ER. A comprehensive evaluation of IL4 variants in ethnically diverse populations: association of total serum IgE levels and asthma in white subjects. J. Allergy Clin. Immunol. 114: 80-87 (2004).

• Batt AM, Ferrari L. Manifestations of chemically induced liver damage. Clin. Chem. 41: 1882-1887 (1995). *

• Battais F, Mothes T, Moneret-Vautrin DA, Pineau F, Kanny G, Popineau Y, Bodinier M, Denery-Papini S. Identification of IgE-binding epitopes on gliadins for patients with food allergy to wheat. Allergy 60: 815-821 (2005). *

• Bauer S, Hangel D, Yu P. Immunobiology of Toll-like receptors in allergic disease. Immunobiology 212: 521-533 (2007).

• Baumer W, Hoppmann J, Rundfeldt C, Kietzmann M. Highly selective phosphodiesterase 4 inhibitors for the treatment of allergic skin diseases and psoriasis. Inflamm. Allergy Drug Targets 6: 17-26 (2007).

• Baur G, Schwalbach G, Tittor W. New aspects of the pathogenesis of primary biliary cirrhosis, a study of 42 patients. Dtsch. Med. Wochenschr. 107: 378-382 (1982).

• Becker A, Chan-Yeung M. Primary asthma prevention: is it possible? Curr. Allergy Asthma Rep. 8: 255-261 (2008).

• Becker J, Delayre-Orthez C, Frossard N, Pons F. Regulation of peroxisome proliferator-activated receptor-alpha expression during lung inflammation. Pulm. Pharmacol. Ther. 21: 324-330 (2008).

• Bednarczuk T, Placha G, Jazdzewski K, Kurylowicz A, Kloza M, Makowska U, Hiromatsu Y, Nauman J. Interleukin-13 gene polymorphisms in patients with Graves' disease. Clin. Endocrinol. (Oxf.) 59: 519-525 (2003). *

• Behrens R, Ruder H. Chronic inflammatory intestinal disease and nephritis. Klin. Padiatr. 204: 61-64 (1992).

• Bell JJ, Divekar RD, Ellis JS, Cascio JA, Haymaker CL, Jain R, Tartar DM, Hoeman CM, Hardaway JC, Zaghouani H. In trans T cell tolerance diminishes autoantibody responses and exacerbates experimental allergic encephalomyelitis. J. Immunol. 180: 1508-1516 (2008). *

• Bell RG. IgE, allergies and helminth parasites: a new perspective on an old conundrum. Immunol. Cell Biol. 74: 337-345 (1996). *

• Bellinghausen I, Konig B, Bottcher I, Knop J, Saloga J. Inhibition of human allergic T-helper type 2 immune responses by induced regulatory T cells requires the combination of interleukin-10-treated dendritic cells and transforming growth factor-beta for their induction. Clin. Exp. Allergy 36: 1546-1555 (2006). *

• Bellou A, Finn PW. Costimulation: critical pathways in the immunologic regulation of asthma. Curr. Allergy Asthma Rep. 5: 149-154 (2005).

• Belvisi MG, Hele DJ. Peroxisome proliferator-activated receptors as novel targets in lung disease. Chest 134: 152-157 (2008). *

• Belvisi MG, Mitchell JA. Targeting PPAR receptors in the airway for the treatment of inflammatory lung disease. Br. J. Pharmacol. 158: 994-1003 (2009).

• Ben-Shoshan M. CTLA-4Ig: uses and future directions. Recent Pat. Inflamm. Allergy Drug Discov. 3: 132-142 (2009).

• Benschop R, Wei T, Na S. Tumor necrosis factor receptor superfamily member 21: TNFR-related death receptor-6, DR6. Adv. Exp. Med. Biol. 647: 186-194 (2009). *

• Benson M, Carlsson L, Guillot G, Jernas M, Langston MA, Rudemo M, Andersson B. A network-based analysis of allergen-challenged CD4+ T cells from patients with allergic rhinitis. Genes Immun. 7: 514-521 (2006). *

• Bento A, Arrobas AM. Asthma and its differential diagnoses. Rev. Port. Pneumol. 15: 1185-1191 (2009).

• Benveniste EN, Qin H. Type I interferons as anti-inflammatory mediators. Sci. STKE 416: pe70 (2007). *

• Berg PA, Klein R. Antimitochondrial antibodies in primary biliary cirrhosis and other disorders: definition and clinical relevance. Dig. Dis. 10: 85-101 (1992).

• Berg PA, Klein R, Rocken M. Cytokines in primary biliary cirrhosis. Semin. Liver Dis. 17: 115-123 (1997).

• Bergamaschi R, Villani S, Crabbio M, Ponzio M, Romani A, Verri A, Bargiggia V, Cosi V. Inverse relationship between multiple sclerosis and allergic respiratory diseases. Neurol. Sci. 30: 115-118 (2009).

• Bergasa NV, Mason A, Floreani A, Heathcote J, Swain MG, Jones DE, Lindor KM, Bassendine MF, Worman HJ. Primary biliary cirrhosis: report of a focus study group. Hepatology 40: 1013-1020 (2004). *

• Berghout J, Min-Oo G, Tam M, Gauthier S, Stevenson MM, Gros P. Identification of a novel cerebral malaria susceptibility locus (Berr5) on mouse chromosome 19. Genes Immun. Oct 29 [Epub ahead of print] (2009).

• Berin MC, Zheng Y, Domaradzki M, Li XM, Sampson HA. Role of TLR4 in allergic sensitization to food proteins in mice. Allergy 61: 64-71 (2006).

• Berson A, Freneaux E, Larrey D, Lepage V, Douay C, Mallet C, Fromenty B, Benhamou JP, Pessayre D. Possible role of HLA in hepatotoxicity. An exploratory study in 71 patients with drug-induced idiosyncratic hepatitis. J. Hepatol. 20: 336-342 (1994).

• Berstad AE, Brandtzaeg P. Does reduced microbial exposure contribute to increased prevalence of allergy? Tidsskr. Nor. Laegeforen. 120: 915-919 (2000).

• Beucher J, Belleguic C, Brinchault G, Deneuville E, Donnio PY, Roussey M. Nocardia farcinica infection in a patient with cystic fibrosis. Rev. Mal. Respir. 27: 76-79 (2010).

• Beyens MN, Guy C, Ollagnier M. Adverse effects of quinine in the treatment of leg cramps. Therapie 54: 59-62 (1999).

• Biecker E, Sauerbruch T. Control of infection in gastrointestinal endoscopy. Dtsch. Med. Wochenschr. 131: 2726-2732 (2006).

• Bielory L. Complementary and alternative interventions in asthma, allergy, and immunology. Ann. Allergy Asthma Immunol. 93 (2 Suppl. 1): S45-S54 (2004).

• Bingle L, Barnes FA, Cross SS, Rassl D, Wallace WA, Campos MA, Bingle CD. Differential epithelial expression of the putative innate immune molecule SPLUNC1 in cystic fibrosis. Respir. Res. 8: 79 (2007). *

• Birch KE, Vukmanovic-Stejic M, Reed JR, Akbar AN, Rustin MH. The immunomodulatory effects of regulatory T cells: implications for immune regulation in the skin. Br. J. Dermatol. 152: 409-417 (2005). *

• Bíro T, Toth BI, Hasko G, Paus R, Pacher P. The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities. Trends Pharmacol. Sci. 30: 411-420 (2009). *

• Birrell MA, De Alba J, Catley MC, Hardaker E, Wong S, Collins M, Clarke DL, Farrow SN, Willson TM, Collins JL, Belvisi MG. Liver X receptor agonists increase airway reactivity in a model of asthma via increasing airway smooth muscle growth. J. Immunol. 181: 4265-4271 (2008). *

• Bischoff S, Crowe SE. Food allergy and the gastrointestinal tract. Curr. Opin. Gastroenterol. 20: 156-161 (2004).

• Bischoff SC. Role of mast cells in allergic and non-allergic immune responses: comparison of human and murine data. Nat. Rev. Immunol. 7: 93-104 (2007). *

• Bischoff SC, Kramer S. Human mast cells, bacteria, and intestinal immunity. Immunol. Rev. 217: 329-337 (2007). *

• Bisgaard H, Bonnelykke K, Sleiman PM, Brasholt M, Chawes B, Kreiner-Moller E, Stage M, Kim C, Tavendale R, Baty F, Pipper CB, Palmer CN, Hakonarsson H. Chromosome 17q21 gene variants are associated with asthma and exacerbations but not atopy in early childhood. Am. J. Respir. Crit. Care Med. 179: 179-185 (2009). *

• Bisset LR, Schmid-Grendelmeier P. Chemokines and their receptors in the pathogenesis of allergic asthma: progress and perspective. Curr. Opin. Pulm. Med. 11: 35-42 (2005).

• Bjorksten B. The hygiene hypothesis: do we still believe in it? Nestle Nutr. Workshop Ser. Pediatr. Program 64: 11-22 (2009).

• Bjornvold M, Munthe-Kaas MC, Egeland T, Joner G, Dahl-Jorgensen K, Njolstad PR, Akselsen HE, Gervin K, Carlsen KC, Carlsen KH, Undlien DE. A TLR2 polymorphism is associated with type 1 diabetes and allergic asthma. Genes Immun. 10: 181-187 (2009).

• Black M. Drug hepatotoxicity. Clin. Liver Dis. 7: xi-xii (2003). *

• Black PN, Sharpe S. Dietary fat and asthma: is there a connection? Eur. Respir. J. 10: 6-12 (1997). *

• Blanchard C, Mingler MK, Vicario M, Abonia JP, Wu YY, Lu TX, Collins MH, Putnam PE, Wells SI, Rothenberg ME. IL-13 involvement in eosinophilic esophagitis: transcriptome analysis and reversibility with glucocorticoids. J. Allergy Clin. Immunol. 120: 1292-1300 (2007). *

• Blanchard C, Wang N, Stringer KF, Mishra A, Fulkerson PC, Abonia JP, Jameson SC, Kirby C, Konikoff MR, Collins MH, Cohen MB, Akers R, Hogan SP, Assa'ad AH, Putnam PE, Aronow BJ, Rothenberg ME. Eotaxin-3 and a uniquely conserved gene-expression profile in eosinophilic esophagitis. J. Clin. Invest. 116: 536-547 (2006). *

• Blankenhorn EP, Butterfield RJ, Rigby R, Cort L, Giambrone D, McDermott P, McEntee K, Solowski N, Meeker ND, Zachary JF, Doerge RW, Teuscher C. Genetic analysis of the influence of pertussis toxin on experimental allergic encephalomyelitis susceptibility: an environmental agent can override genetic checkpoints. J. Immunol. 164: 3420-3425 (2000). *

• Blazquez AB, Knight AK, Getachew H, Bromberg JS, Lira SA, Mayer L, Berin MC. A functional role for CCR6 on pro-allergic T cells in the gastrointestinal tract. Gastroenterology 138: 275-284.e4 (2010). *

• Bloomfield SF, Stanwell-Smith R, Crevel RW, Pickup J. Too clean, or not too clean: the hygiene hypothesis and home hygiene. Clin. Exp. Allergy 36: 402-425 (2006). *

• Blossom DB, Kallen AJ, Patel PR, Elward A, Robinson L, Gao G, Langer R, Perkins KM, Jaeger JL, Kurkjian KM, Jones M, Schillie SF, Shehab N, Ketterer D, Venkataraman G, Kishimoto TK, Shriver Z, McMahon AW, Austen KF, Kozlowski S, Srinivasan A, et al. Outbreak of adverse reactions associated with contaminated heparin. N. Engl. J. Med. 359: 2674-2684 (2008). *

• Bolton C. Recent advances in the pharmacological control of experimental allergic encephalomyelitis (EAE) and the implications for multiple sclerosis treatment. Mult. Scler. 1: 143-149 (1995).

• Bombardieri S, Ruiz AA, Fardellone P, Geusens P, McKenna F, Unnebrink K, Oezer U, Kary S, Kupper H, Burmester AG. Effectiveness of adalimumab for rheumatoid arthritis in patients with a history of TNF-antagonist therapy in clinical practice. Rheumatology (Oxford) 46: 1191-1199 (2007). *

• Boniface K, Blom B, Liu YJ, de Waal Malefyt R. From interleukin-23 to T-helper 17 cells: human T-helper cell differentiation revisited. Immunol. Rev. 226: 132-146 (2008). *

• Bonnel AS, Quinque K, Le Roux P, Le Luyer B. Semi-invasive necrotic aspergillosis in a child with cystic fibrosis. Rev. Mal. Respir. 23: 343-347 (2006).

• Boranic M, Sabioncello A, Gabrilovac J. Psychoneuroimmunology - regulation of immunity at the systemic level. Lijec. Vjesn. 130: 62-67 (2008).

• Borchers AT, Keen CL, Gershwin ME. Fatalities following allergen immunotherapy. Clin. Rev. Allergy Immunol. 27: 147-158 (2004).

• Borrego F, Kabat J, Kim DK, Lieto L, Maasho K, Pena J, Solana R, Coligan JE. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Mol. Immunol. 38: 637-660 (2002). *

• Bossuyt P, Vergauwe P, Inderadjaja N, Vermeire S. Azathioprine induced colitis: a case report and review of the literature. Acta Gastroenterol. Belg. 70: 302-305 (2007).

• Bottcher I, Bellinghausen I, Konig B, Knop J, Saloga J. Different regulation of T helper 1- and T helper 2-promoting cytokine signalling factors in human dendritic cells after exposure to protein versus contact allergens. Immunology 123: 139-144 (2008). *

• Bottini E, Bergamaschi A, Magrini A, Spina C, Ammendola L, Grassi S, Bottini N, Gloria-Bottini F. Allergy and ACP1 genetic polymorphism. Allergy Asthma Proc. 28: 87-92 (2007).

• Bottini N, Stefanini L, Lucarelli P, Bottini E. Adaptation to past malarial endemia and susceptibility to common diseases in modern populations: a study of adenosine deaminase and MN blood group genetic polymorphisms. Am. J. Phys. Anthropol. 128: 194-198 (2005). *

• Boudousquie C, Pellaton C, Barbier N, Spertini F. CD4+CD25+ T cell depletion impairs tolerance induction in a murine model of asthma. Clin. Exp. Allergy 39: 1415-1426 (2009). *

• Boyle MP. The spectrum of CFTR-related disease. Intern. Med. 40: 522-525 (2001). *

• Boyton R. The role of natural killer T cells in lung inflammation. J. Pathol. 214: 276-282 (2008). *

• Boyton RJ. Regulation of immunity in bronchiectasis. Med. Mycol. 47 Suppl. 1: S175-S182 (2009).

• Braat H, van den Brande J, van Tol E, Hommes D, Peppelenbosch M, van Deventer S. Lactobacillus rhamnosus induces peripheral hyporesponsiveness in stimulated CD4+ T cells via modulation of dendritic cell function. Am. J. Clin. Nutr. 80: 1618-1625 (2004). *

• Braddock M, Murray C. 10th Anniversary Inflammation and Immune Diseases Drug Discovery and Development Summit 20 - 21 March 2006, New Brunswick, USA. Expert Opin. Investig. Drugs 15: 721-727 (2006).

• Brahmachari S, Pahan K. Sodium benzoate, a food additive and a metabolite of cinnamon, modifies T cells at multiple steps and inhibits adoptive transfer of experimental allergic encephalomyelitis. J. Immunol. 179: 275-283 (2007). *

• Brahmachari S, Pahan K. Role of cytokine p40 family in multiple sclerosis. Minerva Med. 99: 105-118 (2008).

• Brandt D, Bernstein JA. Questionnaire evaluation and risk factor identification for nonallergic vasomotor rhinitis. Ann. Allergy Asthma Immunol. 96: 526-532 (2006).

• Brandtzaeg PE. Current understanding of gastrointestinal immunoregulation and its relation to food allergy. Ann. N. Y. Acad. Sci. 964: 13-45 (2002). *

• Breidert M, Janssen-Langenstein R, Hambrecht S. A 63 year old Turkish woman with recurrent pneumonia. Internist (Berl.) 48: 420-425 (2007).

• Brenzovich J, Macey M, Fernando J, Chong HJ, Barnstein B, Mirmonsef P, Morales JK, Kimura A, Cruz TD, Ryan JJ. IgE signaling suppresses FcvarepsilonRIbeta expression. J. Leukoc. Biol. 86: 1351-1358 (2009). *

• Breslow RG, Rao JJ, Xing W, Hong DI, Barrett NA, Katz HR. Inhibition of Th2 adaptive immune responses and pulmonary inflammation by leukocyte Ig-like receptor B4 on dendritic cells. J. Immunol. 184: 1003-1013 (2010).

• British Society of Gastroenterology. Antibiotic prophylaxis in gastrointestinal endoscopy. BSG Guidelines in Gastroenterology, p. 1-10, January (2001). *

• Brogden RN, Sorkin EM. Mesalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in chronic inflammatory bowel disease. Drugs 38: 500-523 (1989).

• Broide DH. Immunomodulation of allergic disease. Annu. Rev. Med. 60: 279-291 (2009). *

• Brouard J, Freymuth F, Bach N, Vabret A, Duhamel JF. Childhood infections: friends or foes? Arch. Pediatr. 11 Suppl. 2: 98s-102s (2004).

• Brown JM, Wilson TM, Metcalfe DD. The mast cell and allergic diseases: role in pathogenesis and implications for therapy. Clin. Exp. Allergy 38: 4-18 (2008). *

• Brown LM, Gridley G, Check D, Landgren O. Risk of multiple myeloma and monoclonal gammopathy of undetermined significance among white and black male United States veterans with prior autoimmune, infectious, inflammatory, and allergic disorders. Blood 111: 3388-3394 (2008). *

• Brown MA, Sayed BA, Christy A. Mast cells and the adaptive immune response. J. Clin. Immunol. 28: 671-676 (2008). *

• Brzoska T, Luger TA, Maaser C, Abels C, Bohm M. alpha-Melanocyte-stimulating hormone and related tripeptides: biochemistry, anti-inflammatory and protective effects in vitro and in vivo and future perspectives for the treatment of immune-mediated inflammatory diseases. Endocr. Rev. 29: 581-602 (2008). *

• Buckley NE. The peripheral cannabinoid receptor knockout mice: an update. Br. J. Pharmacol. 153: 309-318 (2008). *

• Buckova D, Holla LI, Znojil V, Vasku A. Polymorphisms of the CD14 gene and atopic phenotypes in Czech patients with IgE-mediated allergy. J. Hum. Genet. 51: 977-983 (2006). *

• Bullard DC, Hu X, Schoeb TR, Collins RG, Beaudet AL, Barnum SR. Intercellular adhesion molecule-1 expression is required on multiple cell types for the development of experimental autoimmune encephalomyelitis. J. Immunol. 178: 851-857 (2007). *

• Bullens DM. Measuring T cell cytokines in allergic upper and lower airway inflammation: can we move to the clinic? Inflamm. Allergy Drug Targets 6: 81-90 (2007).

• Bullens DM, Ceuppens JL. Influence of Toll-like-receptor ligands on the dendritic cell-T cell interactions: therapeutic options for allergic diseases? Mini-review. Inflamm. Allergy Drug Targets 7: 211-216 (2008).

• Bullens DM, Truyen E, Coteur L, Dilissen E, Hellings PW, Dupont LJ, Ceuppens JL. IL-17 mRNA in sputum of asthmatic patients: linking T cell driven inflammation and granulocytic influx? Respir. Res. 7: 135 (2006). *

• Burgess JK, Boustany S, Moir LM, Weckmann M, Lau JY, Grafton K, Baraket M, Hansbro PM, Hansbro NG, Foster PS, Black JL, Oliver BG. Reduction of tumstatin in asthmatic airways contributes to angiogenesis, inflammation and hyperresponsiveness. Am. J. Respir. Crit. Care Med. Oct 29 [Epub ahead of print] (2009). *

• Burgess SJ, Marusina AI, Pathmanathan I, Borrego F, Coligan JE. IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells. J. Immunol. 176: 1490-1497 (2006). *

• Burkart KM, Barton SJ, Holloway JW, Yang IA, Cakebread JA, Cruikshank W, Little F, Jin X, Farrer LA, Clough JB, Keith TP, Holgate S, Center DM, O'Connor GT. Association of asthma with a functional promoter polymorphism in the IL16 gene. J. Allergy Clin. Immunol. 117: 86-91 (2006). *

• Burks AW Jr, Steele RW. Selective IgA deficiency. Ann. Allergy 57: 3-13 (1986).

• Burks W, Jones SM, Berseth CL, Harris C, Sampson HA, Scalabrin DM. Hypoallergenicity and effects on growth and tolerance of a new amino acid-based formula with docosahexaenoic acid and arachidonic acid. J. Pediatr. 153: 266-271 (2008). *

• Burrows JA, Nissen LM, Kirkpatrick CM, Bell SC. Beta-lactam allergy in adults with cystic fibrosis. J. Cyst. Fibros. 6: 297-303 (2007).

• Buschhausen L, Kruis W, Aymaz S, Weber M, Krakamp B. Characterization of proteinuria in patients with ulcerative colitis and therapy with aminosalicylates. Med. Klin. (Munich) 101: 791-795 (2006).

• Cabranes A, Pryce G, Baker D, Fernandez-Ruiz J. Changes in CB(1) receptors in motor-related brain structures of chronic relapsing experimental allergic encephalomyelitis mice. Brain Res. 1107: 199-205 (2006).

• Cabrelle A, Dell'aica I, Melchiori L, Carraro S, Brunetta E, Niero R, Scquizzato E, D'Intino G, Calz L, Garbisa S, Agostini C. Hyperforin down-regulates effector function of activated T lymphocytes and shows efficacy against Th1-triggered CNS inflammatory-demyelinating disease. J. Leukoc. Biol. 83: 212-219 (2008). *

• Cakir E, Uyan ZS, Ersu RH, Karadag B, Karakoc F, Dagli E. Mucoid impaction: an unusual form of allergic bronchopulmonary aspergillosis in a patient with cystic fibrosis. Pediatr. Pulmonol. 41: 1103-1107 (2006).

• Cakir M, Akcay S, Karakas T, Gedik Y, Okten A, Orhan F. Prevalence of atopy in children with type 1 diabetes mellitus, hepatitis B virus carriers, and healthy children: role of T helper 1 (Th1)-type immune response. Allergy Asthma Proc. 29: 166-170 (2008).

• Calabuig E, Salavert M. Infectious risk. Actas Dermosifiliogr. 99 Suppl. 4: 14-22 (2008).

• Calder PC, Krauss-Etschmann S, de Jong EC, Dupont C, Frick JS, Frokiaer H, Heinrich J, Garn H, Koletzko S, Lack G, Mattelio G, Renz H, Sangild PT, Schrezenmeir J, Stulnig TM, Thymann T, Wold AE, Koletzko B. Early nutrition and immunity - progress and perspectives. Br. J. Nutr. 96: 774-790 (2006). *

• Calenoff E, Zhao JC, Derlacki EL, Harrison WH, Selmeczi K, Dutra JC, Olson IR, Hanson DG. Patients with Meniere's disease possess IgE reacting with herpes family viruses. Arch. Otolaryngol. Head Neck Surg. 121: 861-864 (1995).

• Camateros P, Moisan J, Henault J, De Sanctis J, Skamene E, Radzioch D. Toll-like receptors, cytokines and the immunotherapeutics of asthma. Curr. Pharm. Des. 12: 2365-2374 (2006).

• Camateros P, Tamaoka M, Hassan M, Marino R, Moisan J, Marion D, Guiot MC, Martin JG, Radzioch D. Chronic asthma induced airway remodeling is prevented by the Toll-like receptor 7/8 ligand S28463. Am. J. Respir. Crit. Care Med. 175: 1241-1249 (2007). *

• Cameron L, Webster RB, Strempel JM, Kiesler P, Kabesch M, Ramachandran H, Yu L, Stern DA, Graves PE, Lohman IC, Wright AL, Halonen M, Klimecki WT, Vercelli D. Th2 cell-selective enhancement of human IL13 transcription by IL13-1112C>T, a polymorphism associated with allergic inflammation. J. Immunol. 177: 8633-8642 (2006). *

• Campbell JD, Buckland KF, McMillan SJ, Kearley J, Oldfield WL, Stern LJ, Gronlund H, van Hage M, Reynolds CJ, Boyton RJ, Cobbold SP, Kay AB, Altmann DM, Lloyd CM, Larche M. Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression. J. Exp. Med. 206: 1535-1547 (2009). *

• Campbell JD, Cho Y, Foster ML, Kanzler H, Kachura MA, Lum JA, Ratcliffe MJ, Sathe A, Leishman AJ, Bahl A, McHale M, Coffman RL, Hessel EM. CpG-containing immunostimulatory DNA sequences elicit TNF-alpha-dependent toxicity in rodents but not in humans. J. Clin. Invest. 119: 2564-2576 (2009). *

• Campi P, Benucci M, Manfredi M, Demoly P. Hypersensitivity reactions to biological agents with special emphasis on tumor necrosis factor-alpha antagonists. Curr. Opin. Allergy Clin. Immunol. 7: 393-403 (2007).

• Campos Alberto EJ, Shimojo N, Suzuki Y, Mashimo Y, Arima T, Matsuura T, Inoue Y, Yamaide A, Tomiita M, Fujii K, Hata A, Kohno Y. IL-10 gene polymorphism, but not TGF-beta1 gene polymorphisms, is associated with food allergy in a Japanese population. Pediatr. Allergy Immunol. 19: 716-721 (2008).

• Campos E, Shimojo N, Inoue Y, Arima T, Suzuki S, Tomiita M, Matsuura T, Hata A, Suzuki Y, Aoyagi M, Kohno Y. No association of polymorphisms in the 5' region of the CD14 gene and food allergy in a Japanese population. Allergol. Int. 56: 23-27 (2007).

• Campos RA, Szczepanik M, Lisbonne M, Itakura A, Leite-de-Moraes M, Askenase PW. Invariant NKT cells rapidly activated via immunization with diverse contact antigens collaborate in vitro with B-1 cells to initiate contact sensitivity. J. Immunol. 177: 3686-3694 (2006). *

• Canavese M, Altruda F, Silengo L. Therapeutic efficacy and immunological response of CCL5 antagonists in models of contact skin reaction. PLoS One 5: e8725 (2010). *

• Cannioto Z, Berti I, Martelossi S, Bruno I, Giurici N, Crovella S, Ventura A. IBD and IBD mimicking enterocolitis in children younger than 2 years of age. Eur. J. Pediatr. 168: 149-155 (2009). *

• Cannon JL, Collins A, Mody PD, Balachandran D, Henriksen KJ, Smith CE, Tong J, Clay BS, Miller SD, Sperling AI. CD43 regulates Th2 differentiation and inflammation. J. Immunol. 180: 7385-7393 (2008). *

• Cao L, Wang J, Zhu Y, Tseu I, Post M. Maternal endotoxin exposure attenuate allergic airway disease in infant rats. Am. J. Physiol. Lung Cell. Mol. Physiol. Jan 29 [Epub ahead of print] (2010). *

• Capini C, Jaturanpinyo M, Chang HI, Mutalik S, McNally A, Street S, Steptoe R, O'Sullivan B, Davies N, Thomas R. Antigen-specific suppression of inflammatory arthritis using liposomes. J. Immunol. 182: 3556-3565 (2009).

• Capoulade-Metay C, Ayouba A, Kfutwah A, Lole K, Petres S, Dudoit Y, Deterre P, Menu E, Barre-Sinoussi F, Debre P, Theodorou I. A natural CCL5/RANTES variant antagonist for CCR1 and CCR3. Immunogenetics 58: 533-541 (2006). *

• Capron A, Dombrowicz D, Capron M. Helminth infections and allergic diseases: from the Th2 paradigm to regulatory networks. Clin. Rev. Allergy Immunol. 26: 25-34 (2004). *

• Cardell LO, Hagge M, Uddman R, Adner M. Downregulation of peroxisome proliferator-activated receptors (PPARs) in nasal polyposis. Respir. Res. 6: 132 (2005). *

• Cardoso CR, Provinciatto PR, Godoi DF, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. IL-4 regulates susceptibility to intestinal inflammation in murine food allergy. Am. J. Physiol. Gastrointest. Liver Physiol. 296: G593-G600 (2009). *

• Cardoso CR, Provinciatto PR, Godoi DF, Vieira TS, Ferreira BR, Teixeira G, Rossi MA, Cunha FQ, Silva JS. B cells are involved in the modulation of pathogenic gut immune response in food-allergic enteropathy. Clin. Exp. Immunol. 154: 153-161 (2008). *

• Cardoso CR, Teixeira G, Provinciatto PR, Godoi DF, Ferreira BR, Milanezi CM, Ferraz DB, Rossi MA, Cunha FQ, Silva JS. Modulation of mucosal immunity in a murine model of food-induced intestinal inflammation. Clin. Exp. Allergy 38: 338-349 (2008). *

• Carey MA, Card JW, Voltz JW, Germolec DR, Korach KS, Zeldin DC. The impact of sex and sex hormones on lung physiology and disease: lessons from animal studies. Am. J. Physiol. Lung Cell. Mol. Physiol. 293: L272-L278 (2007). *

• Carlen L, Sakuraba K, Stahle M, Sanchez F. HLA-C expression pattern is spatially different between psoriasis and eczema skin lesions. J. Invest. Dermatol. 127: 342-348 (2007). *

• Carlos Moraes Dos Santos D, da Silva Gomes Martinho JM, Pacheco-Moreira LF, Carvalho Viana de Araujo C, Caroli-Bottino A, Pannain VL, Soares Trinta K, Gandini M, da Costa Neves PC, de Souza Matos DC, Goncalves Caputo LF, Pelajo-Machado M, Alves Pinto M. Eosinophils involved in fulminant hepatic failure are associated with high interleukin-6 expression and absence of interleukin-5 in liver and peripheral blood. Liver Int. 29: 544-551 (2009). *

• Carnegie PR, Bencina B, Lamoureux G. Experimental allergic encephalomyelitis. Isolation of basic proteins and polypeptides from central nervous tissue. Biochem. J. 105: 559-568 (1967). *

• Carneiro AC, Lemos AC, Arruda SM, Santana MA. Prevalence of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis in the state of Bahia, Brazil. J. Bras. Pneumol. 34: 900-906 (2008).

• Carrascosa JM, Benvenuti F, Rodriguez C, Ferrandiz C. Characteristics of patients with hand dermatitis referred to the contact dermatitis unit of a tertiary hospital and impact of patch testing on diagnosis. Actas Dermosifiliogr. 100: 493-498 (2009).

• Carvalho A, Pasqualotto AC, Pitzurra L, Romani L, Denning DW, Rodrigues F. Polymorphisms in Toll-like receptor genes and susceptibility to pulmonary aspergillosis. J. Infect. Dis. 197: 618-621 (2008). *

• Carvalho AT, Elia CC, de Souza HS, Elias PR, Pontes EL, Lukashok HP, de Freitas FC, Lapa e Silva JR. Immunohistochemical study of intestinal eosinophils in inflammatory bowel disease. J. Clin. Gastroenterol. 36: 120-125 (2003).

• Carvalho L, Sun J, Kane C, Marshall F, Krawczyk C, Pearce EJ. Review series on helminths, immune modulation and the hygiene hypothesis: mechanisms underlying helminth modulation of dendritic cell function. Immunology 126: 28-34 (2009). *

• Casale TB, Kessler J, Romero FA. Safety of the intranasal Toll-like receptor 4 agonist CRX-675 in allergic rhinitis. Ann. Allergy Asthma Immunol. 97: 454-456 (2006).

• Casanova JL, Fieschi C, Bustamante J, Reichenbach J, Remus N, von Bernuth H, Picard C. From idiopathic infectious diseases to novel primary immunodeficiencies. J. Allergy Clin. Immunol. 116: 426-430 (2005). *

• Casas R, Lindau C, Zetterstrom O, Duchen K. Downregulation of CXCR6 and CXCR3 in lymphocytes from birch-allergic patients. Scand. J. Immunol. 68: 351-361 (2008). *

• Casella G, Villanacci V, Fisogni S, Cambareri AR, DI Bella C, Corazzi N, Gorla S, Baldini V, Bassotti G. Colonic left-side increase of eosinophils: a clue of drug-related colitis in adults. Aliment. Pharmacol. Ther. 29: 535-541 (2009). *

• Castell JV, Castell M. Allergic hepatitis induced by drugs. Curr. Opin. Allergy Clin. Immunol. 6: 258-265 (2006).

• Castellani C, Quinzii C, Altieri S, Mastella G, Assael BM. A pilot survey of cystic fibrosis clinical manifestations in CFTR mutation heterozygotes. Genet. Test. 5: 249-254 (2001).

• Cebeci AN, Nuhoglu Y, Arslanoglu I, Erguven M, Agachan N. The role of IL-18 in Th1/Th2 balance in children. Allergy Asthma Proc. 27: 365-370 (2006).

• Celik U, Kocabas E. New approaches in antibiotic therapies in chronic pulmonary diseases. Tuberk. Toraks. 56: 353-363 (2008).

• Cesinaro AM, Nannini N, Migaldi M, Pepe P, Maiorana A. Psoriasis vs allergic contact dermatitis in palms and soles: a quantitative histologic and immunohistochemical study. APMIS 117: 629-634 (2009).

• Chae SC, Lee YC, Park YR, Shin JS, Song JH, Oh GJ, Hong ST, Pae HO, Choi BM, Chung HT. Analysis of the polymorphisms in eotaxin gene family and their association with asthma, IgE, and eosinophil. Biochem. Biophys. Res. Commun. 320: 131-137 (2004). *

• Chae SC, Li CS, Kim KM, Yang JY, Zhang Q, Lee YC, Yang YS, Chung HT. Identification of polymorphisms in human interleukin-27 and their association with asthma in a Korean population. J. Hum. Genet. 52: 355-361 (2007). *

• Chae SC, Park YR, Lee YC, Lee JH, Chung HT. The association of TIM-3 gene polymorphism with atopic disease in Korean population. Hum. Immunol. 65: 1427-1431 (2004).

• Chae SC, Park YR, Li CS, Lee JH, Yang YS, Zhang Q, Kim KS, Chung HT. Analysis of the variations in IL-28RA gene and their association with allergic rhinitis. Exp. Mol. Med. 38: 302-309 (2006). *

• Chae SC, Park YR, Shim SC, Lee IK, Chung HT. Eotaxin-3 gene polymorphisms are associated with rheumatoid arthritis in a Korean population. Hum. Immunol. 66: 314-320 (2005).

• Chae SC, Park YR, Song JH, Shim SC, Yoon KS, Chung HT. The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population. Immunogenetics 56: 696-701 (2005). *

• Chai SK, Altman GM, Yazdanbakhsh M, Tsuji J, Godat L, Takaro TK. Production of interleukin 10 and transforming growth factor beta in concomitant allergy and autoimmunity. Ann. Allergy Asthma Immunol. 94: 279-285 (2005).

• Chakrabarti R, Subramaniam V, Abdalla S, Jothy S, Prud'homme GJ. Tranilast inhibits the growth and metastasis of mammary carcinoma. Anticancer Drugs 20: 334-345 (2009).

• Chamnan P, Shine BS, Haworth CS, Bilton D, Adler AI. Diabetes as a determinant of mortality in cystic fibrosis. Diabetes Care Nov 16 [Epub ahead of print] (2009).

• Chan AY, Westcott JM, Mooney JM, Wakeland EK, Schatzle JD. The role of SAP and the SLAM family in autoimmunity. Curr. Opin. Immunol. 18: 656-664 (2006).

• Chan IH, Lee DL, Ho OY, Wong EW, Lam YY, Tang NL, Chan MH, Abdullah VJ, Wong CK, Lam CW. High-level expression of early growth response-1 and association of polymorphism with total IgE and atopy in allergic rhinitis adults. Clin. Chim. Acta 411: 67-71 (2010). *

• Chan IH, Tang NL, Leung TF, Lam YY, Wong GW, Wong CK, Lam CW. Association of plasma soluble CTLA-4 with lung function and gene polymorphism in Chinese asthmatic children. Int. Arch. Allergy Immunol. 152: 113-121 (2009).

• Chan JL, Davis-Reed L, Kimball AB. Counter-regulatory balance: atopic dermatitis in patients undergoing infliximab infusion therapy. J. Drugs Dermatol. 3: 315-318 (2004).

• Chang C. The immune effects of naturally occurring and synthetic nanoparticles. J. Autoimmun. Dec 6 [Epub ahead of print] (2009).

• Chang HH, Chen CS, Lin JY. Dietary perilla oil lowers serum lipids and ovalbumin-specific IgG1, but increases total IgE levels in ovalbumin-challenged mice. Food Chem. Toxicol. 47: 848-854 (2009).

• Chang HH, Chen CS, Lin JY. Dietary perilla oil lowers serum lipids and ovalbumin-specific IgG1, but increases total IgE levels in ovalbumin-challenged mice. Food Chem. Toxicol. Jan 15 [Epub ahead of print] (2009).

• Chapat L, Chemin K, Dubois B, Bourdet-Sicard R, Kaiserlian D. Lactobacillus casei reduces CD8(+) T cell-mediated skin inflammation. Eur. J. Immunol. 34: 2520-2528 (2004). *

• Chapkin RS, Davidson LA, Ly L, Weeks BR, Lupton JR, McMurray DN. Immunomodulatory effects of (n-3) fatty acids: putative link to inflammation and colon cancer. J. Nutr. 137: 200S-204S (2007). *

• Charles J, Chaperot L, Salameire D, Domizio JD, Aspord C, Gressin R, Jacob MC, Richard MJ, Beani JC, Plumas J, Leccia MT. Plasmacytoid dendritic cells and dermatological disorders: focus on their role in autoimmunity and cancer. Eur. J. Dermatol. Oct 22 [Epub ahead of print] (2009).

• Charng MJ, Wu CH. Transcriptional activation of p21 by Tranilast is mediated via transforming growth factor beta signal pathway. Br. J. Pharmacol. 147: 117-124 (2006). *

• Chatila TA. Molecular mechanisms of regulatory T-cell development. Chem. Immunol. Allergy 94: 16-28 (2008).

• Chatila TA. Role of regulatory T cells in human diseases. J. Allergy Clin. Immunol. 116: 949-959 (2005). *

• Chatila TA. Regulatory T cells: key players in tolerance and autoimmunity. Endocrinol. Metab. Clin. North Am. 38: 265-272 (2009).

• Chatterjee R, Batra J, Ghosh B. A common exonic variant of interleukin-21 confers susceptibility to atopic asthma. Int. Arch. Allergy Immunol. 148: 137-146 (2008).

• Chaudhary N, Staab JF, Marr KA. Healthy human T-cell responses to Aspergillus fumigatus antigens. PLoS One 5: e9036 (2010). *

• Chearwae W, Bright JJ. 15-Deoxy-delta(12,14)-prostaglandin J(2) and curcumin modulate the expression of Toll-like receptors 4 and 9 in autoimmune T lymphocyte. J. Clin. Immunol. 28: 558-570 (2008). *

• Chen CL, Wang YM, Liu CF, Wang JY. The effect of water-soluble chitosan on macrophage activation and the attenuation of mite allergen-induced airway inflammation. Biomaterials 29: 2173-2182 (2008).

• Chen K, Le Y, Liu Y, Gong W, Ying G, Huang J, Yoshimura T, Tessarollo L, Wang JM. Cutting edge: a critical role for the G protein-coupled receptor mFPR2 in airway inflammation and immune responses. J. Immunol. Mar 3 [Epub ahead of print] (2010).

• Chen W, Jin W, Hardegen N, Lei KJ, Li L, Marinos N, McGrady G, Wahl SM. Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J. Exp. Med. 198: 1875-1886 (2003). *

• Chen W, Zhang L, Liang B, Saenger Y, Li J, Chess L, Jiang H. Perceiving the avidity of T cell activation can be translated into peripheral T cell regulation. Proc. Natl. Acad. Sci. U.S.A. 104: 20472-20477 (2007). *

• Chen YH, Lee MF, Tsai JJ, Wu HJ, Hwang GY. Specific IgE and IgG responses and cytokine profile in subjects with allergic reactions to biting midge Forcipomyia taiwana. Int. Arch. Allergy Immunol. 150: 66-74 (2009).

• Cheng L, Enomoto T, Hirota T, Shimizu M, Takahashi N, Akahoshi M, Matsuda A, Dake Y, Doi S, Enomoto K, Yamasaki A, Fukuda S, Mao XQ, Hopkin JM, Tamari M, Shirakawa T. Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen. Clin. Exp. Allergy 34: 1192-1201 (2004). *

• Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils. J. Allergy Clin. Immunol. 121: 1484-1490 (2008). *

• Cheung PF, Wong CK, Ip WK, Lam CW. IL-25 regulates the expression of adhesion molecules on eosinophils: mechanism of eosinophilia in allergic inflammation. Allergy 61: 878-885 (2006). *

• Cheung PF, Wong CK, Lam CW. Molecular mechanisms of cytokine and chemokine release from eosinophils activated by IL-17A, IL-17F, and IL-23: implication for Th17 lymphocytes-mediated allergic inflammation. J. Immunol. 180: 5625-5635 (2008). *

• Chikamatsu K, Sakakura K, Matsuoka T, Endo S, Takahashi G, Matsuzaki Z, Masuyama K. Analysis of T-helper responses and FOXP3 gene expression in patients with Japanese cedar pollinosis. Am. J. Rhinol. 22: 582-588 (2008).

• Chin J. Intestinal microflora: negotiating health outcomes with the warring community within us. Asia Pac. J. Clin. Nutr. 13: S24-S25 (2004).

• Chin JJ. Revisiting the "hygiene hypothesis" in gastrointestinal allergy. Curr. Opin. Gastroenterol. 18: 705-710 (2002).

• Chinen J, Finkelman F, Shearer WT. Advances in basic and clinical immunology. J. Allergy Clin. Immunol. 118: 489-495 (2006). *

• Chinen J, Shearer WT. Advances in basic and clinical immunology in 2006. J. Allergy Clin. Immunol. 120: 263-270 (2007). *

• Chivu RD, Chivu LI, Ion DA, Barbu C, Fica S. Allergic reactions to antithyroid drugs are associated with autoimmunity a retrospective case-control study. Rev. Med. Chir. Soc. Med. Nat. Iasi. 110: 830-832 (2006).

• Cho YC, You SK, Kim HJ, Cho CW, Lee IS, Kang BY. Xanthohumol inhibits IL-12 production and reduces chronic allergic contact dermatitis. Int. Immunopharmacol. Feb 5 [Epub ahead of print] (2010).

• Choi JM, Ahn MH, Chae WJ, Jung YG, Park JC, Song HM, Kim YE, Shin JA, Park CS, Park JW, Park TK, Lee JH, Seo BF, Kim KD, Kim ES, Lee DH, Lee SK, Lee SK. Intranasal delivery of the cytoplasmic domain of CTLA-4 using a novel protein transduction domain prevents allergic inflammation. Nat. Med. 12: 574-579 (2006). *

• Chotirmall SH, Branagan P, Gunaratnam C, McElvaney NG. Aspergillus/allergic bronchopulmonary aspergillosis in an Irish cystic fibrosis population: a diagnostically challenging entity. Respir. Care 53: 1035-1041 (2008).

• Chouchane L, Sfar I, Bousaffara R, El Kamel A, Sfar MT, Ismail A. A repeat polymorphism in interleukin-4 gene is highly associated with specific clinical phenotypes of asthma. Int. Arch. Allergy Immunol. 120: 50-55 (1999).

• Chow J, Mazmanian SK. Getting the bugs out of the immune system: do bacterial microbiota "fix" intestinal T cell responses? Cell Host Microbe 5: 8-12 (2009).

• Christy AL, Brown MA. The multitasking mast cell: positive and negative roles in the progression of autoimmunity. J. Immunol. 179: 2673-2679 (2007). *

• Chrousos GP, Kino T. Glucocorticoid signaling in the cell. Ann. N. Y. Acad. Sci. 1179: 153-166 (2009). *

• Chun E, Lee SH, Lee SY, Shim EJ, Cho SH, Min KU, Kim YY, Park HW. Toll-like receptor expression on peripheral blood mononuclear cells in asthmatics; implications for asthma management. J. Clin. Immunol. Jan 14 [Epub ahead of print] (2010). *

• Chung SW, Kang BY, Kim TS. Inhibition of interleukin-4 production in CD4+ T cells by peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligands: involvement of physical association between PPAR-gamma and the nuclear factor of activated T cells transcription factor. Mol. Pharmacol. 64: 1169-1179 (2003). *

• Chung YS, Cha HE, Kang IG, Hwang YJ, Kim ST. Polymorphism at the glutathione S-transferase P1 locus in Korean patients with perennial allergic rhinitis. Am. J. Rhinol. 20: 648-651 (2006).

• Cichy M, Adamek-Guzik T, Uracz D, Uracz W, Czerniawska-Mysik G, Korbut R, Guzik TJ. The functional relevance of Arg16Gly and Gln27Glu-beta2-adrenoreceptor polymorphism in patients with asthma and allergic rhinitis. Folia. Med. Cracov. 46: 33-51 (2005).

• Ciprandi G, Colombo BM, Contini P, Cagnati P, Pistorio A, Puppo F, Murdaca G. Soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. Allergy 63: 1335-1338 (2008).

• Ciprandi G, Contini P, Fenoglio D, Sormani MP, Negrini S, Puppo F, Indiveri F. Relationship between soluble HLA-G and HLA-A,-B,-C serum levels, and interferon-gamma production after sublingual immunotherapy in patients with allergic rhinitis. Hum. Immunol. 69: 409-413 (2008).

• Ciprandi G, Contini P, Murdaca G, Deamici M, Gallina AM, Puppo F. Soluble serum HLA-G and HLA-A,-B,-C molecules in patients with seasonal allergic rhinitis exposed to pollens. Int. Immunopharmacol. 9: 1058-1062 (2009).

• Ciprandi G, Contini P, Pistorio A, Murdaca G, Puppo F. Sublingual immunotherapy reduces soluble HLA-G and HLA-A,-B,-C serum levels in patients with allergic rhinitis. Int. Immunopharmacol. 9: 253-257 (2009).

• Ciprandi G, De Amici M, Murdaca G, Fenoglio D, Ricciardolo F, Marseglia G, Tosca M. Serum interleukin-17 levels are related to clinical severity in allergic rhinitis. Allergy 64: 1375-1378 (2009). *

• Ciprandi G, De Amici M, Negrini S, Marseglia G, Tosca MA. TGF-beta and IL-17 serum levels and specific immunotherapy. Int. Immunopharmacol. 9: 1247-1249 (2009).

• Ciprandi G, Fenoglio D, De Amici M, Quaglini S, Negrini S, Filaci G. Serum IL-17 levels in patients with allergic rhinitis. J. Allergy Clin. Immunol. 122: 650-651.e2 (2008). *

• Ciprandi G, Filaci G, Battaglia F, Fenoglio D. Peripheral Th17 cells in allergic rhinitis: new evidence. Int. Immunopharmacol. Nov 16 [Epub ahead of print] (2009).

• Clarke E, Rahman N, Page N, Rolph MS, Stewart GJ, Jones GJ. Functional characterization of the atopy-associated gene PHF11. J. Allergy Clin. Immunol. 121: 1148-1154.e3 (2008). *

• Clarke P. Urticaria. Aust. Fam. Physician 33: 501-503 (2004).

• Claudio E, Sonder SU, Saret S, Carvalho G, Ramalingam TR, Wynn TA, Chariot A, Garcia-Perganeda A, Leonardi A, Paun A, Chen A, Ren NY, Wang H, Siebenlist U. The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation. J. Immunol. 182: 1617-1630 (2009).

• Clerici N, Fernandez M, Saiz I, Sainz T, Polanco I. Human leukocyte antigen alleles and haplotypes associated with selective immunoglobulin A deficiency in Spanish pediatric patients. J. Pediatr. Gastroenterol. Nutr. 16: 381-386 (1993).

• Codolo G, Mazzi P, Amedei A, Del Prete G, Berton G, D'Elios MM, de Bernard M. The neutrophil activating protein of Helicobacter pylori down-modulates Th2 inflammation in OVA-induced allergic asthma. Cell. Microbiol. 10: 2355-2363 (2008). *

• Cohen-Cymberknoh M, Blau H, Shoseyov D, Mei-Zahav M, Efrati O, Armoni S, Kerem E. Intravenous monthly pulse methylprednisolone treatment for ABPA in patients with cystic fibrosis. J. Cyst. Fibros. 8: 253-257 (2009).

• Cohn L, Elias JA, Chupp GL. Asthma: mechanisms of disease persistence and progression. Annu. Rev. Immunol. 22: 789-815 (2004). *

• Collington SJ, Westwick J, Williams TJ, Weller CL. The function of CCR3 on mouse bone marrow-derived mast cells in vitro. Immunology 129: 115-124 (2010). *

• Colombo G, Yacoub MR, Burastero SE, Garattini E, Girlanda S, Saporiti N, Salvo F, Sabbadini MG. Multiple drug hypersensivity: insight into the underlying mechanism and correlation with autoimmune diseases. Eur. Ann. Allergy Clin. Immunol. 41: 50-55 (2009).

• Comabella M, Martin R. Genomics in multiple sclerosis - current state and future directions. J. Neuroimmunol. 187: 1-8 (2007).

• Commins S, Steinke JW, Borish L. The extended IL-10 superfamily: IL-10, IL-19, IL-20, IL-22, IL-24, IL-26, IL-28, and IL-29. J. Allergy Clin. Immunol. 121: 1108-1111 (2008). *

• Conroy ME, Shi HN, Walker WA. The long-term health effects of neonatal microbial flora. Curr. Opin. Allergy Clin. Immunol. 9: 197-201 (2009).

• Constabel H, Stankov MV, Hartwig C, Tschernig T, Behrens GM. Impaired lung dendritic cell migration and T cell stimulation induced by immunostimulatory oligonucleotides contribute to reduced allergic airway inflammation. J. Immunol. 183: 3443-3453 (2009).

• Cook EB, Stahl JL, Graziano FM, Barney NP. Regulation of the receptor for TNFalpha, TNFR1, in human conjunctival epithelial cells. Invest. Ophthalmol. Vis. Sci. 49: 3992-3998 (2008). *

• Cooke A. Review series on helminths, immune modulation and the hygiene hypothesis: how might infection modulate the onset of type 1 diabetes? Immunology 126: 12-17 (2009). *

• Cookson WO, Moffatt MF. Genetics of asthma and allergic disease. Hum. Mol. Genet. 9: 2359-2364 (2000). *

• Cornejo-Garcia JA, Fernandez TD, Torres MJ, Carballo M, Hernan I, Antunez C, Blanca M, Mayorga C. Differential cytokine and transcription factor expression in patients with allergic reactions to drugs. Allergy 62: 1429-1438 (2007). *

• Correale J, Farez M, Gilmore W. Vaccines for multiple sclerosis: progress to date. CNS Drugs 22: 175-198 (2008).

• Corvo M, Ghiglioni D, Gemellaro L, Sarratud T, Fiocchi A. Gastrointestinal signs and symptoms of allergic diseases in children. Pediatr. Med. Chir. 31: 153-159 (2009).

• Corydon TJ, Haagerup A, Jensen TG, Binderup HG, Petersen MS, Kaltoft K, Vestbo J, Kruse TA, Borglum AD. A functional CD86 polymorphism associated with asthma and related allergic disorders. J. Med. Genet. 44: 509-515 (2007).

• Costa Carvalho BT, Nagao AT, Arslanian C, Carneiro Sampaio MM, Naspitz CK, Sorensen RU, Leiva L, Sole D. Immunological evaluation of allergic respiratory children with recurrent sinusitis. Pediatr. Allergy Immunol. 16: 534-538 (2005).

• Coutinho A, Caramalho I, Seixas E, Demengeot J. Thymic commitment of regulatory T cells is a pathway of TCR-dependent selection that isolates repertoires undergoing positive or negative selection. Curr. Top. Microbiol. Immunol. 293: 43-71 (2005).

• Cox LS. How safe are the biologicals in treating asthma and rhinitis? Allergy Asthma Clin. Immunol. 5: 4 (2009). *

• Cox MJ, Huang YJ, Fujimura KE, Liu JT, McKean M, Boushey HA, Segal MR, Brodie EL, Cabana MD, Lynch SV. Lactobacillus casei abundance is associated with profound shifts in the infant gut microbiome. PLoS One 5: e8745 (2010). *

• Coyle AJ, Gutierrez-Ramos JC. The role of ICOS and other costimulatory molecules in allergy and asthma. Springer Semin. Immunopathol. 25: 349-359 (2004). *

• Crameri R, Weichel M, Glaser AG, Fluckiger S, Rhyner C. Fungal allergies: a yet unsolved problem. Chem. Immunol. Allergy 91: 121-133 (2006).

• Creusot RJ, Yaghoubi SS, Chang P, Chia J, Contag CH, Gambhir SS, Fathman CG. Lymphoid tissue specific homing of bone marrow-derived dendritic cells. Blood 113: 6638-6647 (2009). *

• Croese J, Wood MJ, Melrose W, Speare R. Allergy controls the population density of Necator americanus in the small intestine. Gastroenterology 131: 402-409 (2006). *

• Crowson AN, Mihm MC Jr, Magro CM. Cutaneous vasculitis: a review. J. Cutan. Pathol. 30: 161-173 (2003). *

• Crowther SD, Rees PJ. Current treatment of asthma - focus on leukotrienes. Expert Opin. Pharmacother. 1: 1021-1040 (2000).

• Csillag A, Boldogh I, Pazmandi K, Magyarics Z, Gogolak P, Sur S, Rajnavolgyi E, Bacsi A. Pollen-induced oxidative stress influences both innate and adaptive immune responses via altering dendritic cell functions. J. Immunol. Jan 29 [Epub ahead of print] (2010).

• Cucchiara S, Falconieri P, Di Nardo G, Parcelii MA, Dito L, Grandinetti A. New therapeutic approach in the management of intestinal disease: probiotics in intestinal disease in paediatric age. Dig. Liver Dis. 34 Suppl. 2: S44-S47 (2002).

• Cudrici C, Ito T, Zafranskaia E, Weerth S, Rus V, Chen H, Niculescu F, Soloviova K, Tegla C, Gherman A, Raine CS, Shin ML, Rus H. Complement C5 regulates the expression of insulin-like growth factor binding proteins in chronic experimental allergic encephalomyelitis. J. Neuroimmunol. 203: 94-103 (2008).

• Curotto de Lafaille MA, Lafaille JJ. Natural and adaptive Foxp3(+) regulatory T cells: more of the same or a division of labor? Immunity 30: 626-635 (2009). *

• D'Acquisto F, Maione F, Pederzoli-Ribeil M. From IL-15 to IL-33: the never-ending list of new players in inflammation. Is it time to forget the humble aspirin and move ahead? Biochem. Pharmacol. 79: 525-534 (2010). *

• D'Acquisto F, Paschalidis N, Sampaio AL, Merghani A, Flower RJ, Perretti M. Impaired T cell activation and increased Th2 lineage commitment in annexin-1-deficient T cells. Eur. J. Immunol. 37: 3131-3142 (2007). *

• d'Albasio G, Trallori G, Ghetti A, Milla M, Nucci A, Pacini F, Morettini A. Intermittent therapy with high-dose 5-aminosalicylic acid enemas for maintaining remission in ulcerative proctosigmoiditis. Dis. Colon Rectum 33: 394-397 (1990).

• D'Amato G, Salzillo A, Piccolo A, D'Amato M, Liccardi G. A review of anti-IgE monoclonal antibody (omalizumab) as add on therapy for severe allergic (IgE-mediated) asthma. Ther. Clin. Risk Manag. 3: 613-619 (2007). *

• D'Arienzo A, Manguso F, Astarita C, D'Armiento FP, Scarpa R, Gargano D, Scaglione G, Vicinanza G, Bennato R, Mazzacca G. Allergy and mucosal eosinophil infiltrate in ulcerative colitis. Scand. J. Gastroenterol. 35: 624-631 (2000). *

• D'Arienzo A, Manguso F, Scarpa R, Astarita C, D'Armiento FP, Bennato R, Gargano D, Sanges M, Mazzacca G. Ulcerative colitis, seronegative spondyloarthropathies and allergic diseases: the search for a link. Scand. J. Gastroenterol. 37: 1156-1163 (2002). *

• D'Elios MM, Andersen LP. Inflammation, immunity, and vaccines for Helicobacter pylori. Helicobacter 14 Suppl. 1: 21-28 (2009). *

• da Silva MF, Nobrega A, Ribeiro RC, Levy MS, Ribeiro OG, Tambourgi DV, Sant'anna DA, da Silva AC. Genetic selection for resistance or susceptibility to oral tolerance imparts correlation to both immunoglobulin E level and mast cell number phenotypes with a profound impact on the atopic potential of the individual. Clin. Exp. Allergy 36: 1399-1407 (2006). *

• Dahten A, Koch C, Ernst D, Schnoller C, Hartmann S, Worm M. Systemic PPARgamma ligation inhibits allergic immune response in the skin. J. Invest. Dermatol. 128: 2211-2218 (2008). *

• Dai KZ, Harbo HF, Celius EG, Oturai A, Sorensen PS, Ryder LP, Datta P, Svejgaard A, Hillert J, Fredrikson S, Sandberg-Wollheim M, Laaksonen M, Myhr KM, Nyland H, Vartdal F, Spurkland A. The T cell regulator gene SH2D2A contributes to the genetic susceptibility of multiple sclerosis. Genes Immun. 2: 263-268 (2001). *

• Dajotoy T, Andersson P, Bjartell A, Lofdahl CG, Tapper H, Egesten A. Human eosinophils produce the T cell-attracting chemokines MIG and IP-10 upon stimulation with IFN-gamma. J. Leukoc. Biol. 76: 685-691 (2004). *

• Dall'asta C, Galaverna G, Mangia M, Sforza S, Dossena A, Marchelli R. Free and bound fumonisins in gluten-free food products. Mol. Nutr. Food Res. 53: 492-499 (2009).

• Danese S, Sans M, Fiocchi C. Inflammatory bowel disease: the role of environmental factors. Autoimmun. Rev. 3: 394-400 (2004).

• Danese S, Semeraro S, Armuzzi A, Papa A, Gasbarrini A. Biological therapies for inflammatory bowel disease: research drives clinics. Mini. Rev. Med. Chem. 6: 771-784 (2006).

• Daniel F, Seksik P, Cacheux W, Jian R, Marteau P. Tolerance of 4-aminosalicylic acid enemas in patients with inflammatory bowel disease and 5-aminosalicylic-induced acute pancreatitis. Inflamm. Bowel Dis. 10: 258-260 (2004). *

• Darabi K, Karulin AY, Boehm BO, Hofstetter HH, Fabry Z, LaManna JC, Chavez JC, Tary-Lehmann M, Lehmann PV. The third signal in T cell-mediated autoimmune disease? J. Immunol. 173: 92-99 (2004). *

• Das D, Graham I, Rose J. Recurrent acute hepatitis in patient receiving pulsed methylprednisolone for multiple sclerosis. Indian J. Gastroenterol. 25: 314-316 (2006). *

• Das UN. Essential fatty acids as possible enhancers of the beneficial actions of probiotics. Nutrition 18: 786 (2002). *

• Daser A, Mitchison H, Mitchison A, Muller B. Non-classical-MHC genetics of immunological disease in man and mouse. The key role of pro-inflammatory cytokine genes. Cytokine 8: 593-597 (1996).

• Dasgupta S, Roy A, Jana M, Hartley DM, Pahan K. Gemfibrozil ameliorates relapsing-remitting experimental autoimmune encephalomyelitis independent of peroxisome proliferator-activated receptor-alpha. Mol. Pharmacol. 72: 934-946 (2007). *

• Davila I, Mullol J, Ferrer M, Bartra J, del Cuvillo A, Montoro J, Jauregui I, Sastre J, Valero A. Genetic aspects of allergic rhinitis. J. Investig. Allergol. Clin. Immunol. 19 Suppl. 1: 25-31 (2009).

• Davis PA, Jenab M, Vanden Heuvel JP, Furlong T, Taylor S. Tree nut and peanut consumption in relation to chronic and metabolic diseases including allergy. J. Nutr. 138: 1757S-1762S (2008). *

• De Angelis M, Rizzello CG, Scala E, De Simone C, Farris GA, Turrini F, Gobbetti M. Probiotic preparation has the capacity to hydrolyze proteins responsible for wheat allergy. J. Food Prot. 70: 135-144 (2007).

• De Bosscher K, Vanden Berghe W, Haegeman G. The interplay between the glucocorticoid receptor and nuclear factor-kappaB or activator protein-1: molecular mechanisms for gene repression. Endocr. Rev. 24: 488-522 (2003). *

• de Gracia J, Alvarez A, Mata F, Guarner L, Vendrell M, Gadtner S, Cobos N. Cystic fibrosis in adults: study of 111 patients. Med. Clin. (Barc.) 119: 605-609 (2002).

• de Langen-Wouterse JJ, Bijl AM, van Grootheest AC. Drug-induced systemic lupus erythematosus: reports to The Netherlands Pharmacovigilance Centre Lareb. Ned. Tijdschr. Geneeskd. 151: 367-370 (2007).

• de Ridder L, Rings EH, Damen GM, Kneepkens CM, Schweizer JJ, Kokke FT, Benninga MA, Norbruis OF, Hoekstra JH, Gijsbers CF, Escher JC. Infliximab dependency in pediatric Crohn's disease: long-term follow-up of an unselected cohort. Inflamm. Bowel Dis. 14: 353-358 (2008). *

• de Valk HA, Klaassen CH, Yntema JB, Hebestreit A, Seidler M, Haase G, Muller FM, Meis JF. Molecular typing and colonization patterns of Aspergillus fumigatus in patients with cystic fibrosis. J. Cyst. Fibros. 8: 110-114 (2009).

• de Vries A, Hazlewood L, Fitch PM, Seckl JR, Foster P, Howie SE. High-fat feeding redirects cytokine responses and decreases allergic airway eosinophilia. Clin. Exp. Allergy 39: 731-739 (2009).

• Deane JA, Hickey MJ. Molecular mechanisms of leukocyte trafficking in T-cell-mediated skin inflammation: insights from intravital imaging. Expert Rev. Mol. Med. 11: e25 (2009).

• Dearman RJ, Kimber I. Characterisation of immune responses to food allergens in mice. Proc. Nutr. Soc. 64: 426-433 (2005). *

• Degner D, Grohmann R, Kropp S, Ruther E, Bender S, Engel RR, Schmidt LG. Severe adverse drug reactions of antidepressants: results of the German multicenter drug surveillance program AMSP. Pharmacopsychiatry 37 Suppl. 1: S39-S45 (2004).

• Del Rio R, Noubade R, Subramanian M, Saligrama N, Diehl S, Rincon M, Teuscher C. SNPs upstream of the minimal promoter control IL-2 expression and are candidates for the autoimmune disease-susceptibility locus Aod2/Idd3/Eae3. Genes Immun. 9: 115-121 (2008). *

• Deleuran B, Abraham DJ. Possible implication of the effector CD4(+) T-cell subpopulation T(H)17 in the pathogenesis of systemic scleroderma. Nat. Clin. Pract. Rheumatol. 3: 682-683 (2007). *

• Deltenre P, Berson A, Marcellin P, Degott C, Biour M, Pessayre D. Mesalazine (5-aminosalicylic acid) induced chronic hepatitis. Gut 44: 886-888 (1999). *

• Deng A, Yao D, Chen S, Liu C, Kang J, Zhou Y, Yu H, Qian C, Wu C, Jiang T, Zhong R, Pei G. beta-Arrestin 1 contributes to primary biliary cirrhosis. Clin. Sci. (Lond.) Dec 21 [Epub ahead of print] (2009). *

• Deng YN, Zhou WB. Expression of TLR4 and TLR9 mRNA in Lewis rats with experimental allergic neuritis. Neuroimmunomodulation 14: 336-342 (2008).

• Desai HG, Gupte PA. Increasing incidence of Crohn's disease in India: is it related to improved sanitation? Indian J. Gastroenterol. 24: 23-24 (2005). *

• Descotes J. Immunotoxicology: role in the safety assessment of drugs. Drug Saf. 28: 127-136 (2005).

• Deurloo DT, van Berkel MA, van Esch BC, Hofhuis F, Nijkamp FP, Oosterwegel MA, van Oosterhout AJ. CD28/CTLA4 double deficient mice demonstrate crucial role for B7 co-stimulation in the induction of allergic lower airways disease. Clin. Exp. Allergy 33: 1297-1304 (2003). *

• Deurloo DT, van Esch BC, Hofstra CL, Nijkamp FP, van Oosterhout AJ. CTLA4-IgG reverses asthma manifestations in a mild but not in a more "severe" ongoing murine model. Am. J. Respir. Cell. Mol. Biol. 25: 751-760 (2001). *

• Devereux G. The increase in the prevalence of asthma and allergy: food for thought. Nat. Rev. Immunol. 6: 869-874 (2006). *

• Devereux G. Session 1: allergic disease nutrition as a potential determinant of asthma. Proc. Nutr. Soc. Dec 8 [Epub ahead of print] (2009). *

• Devosse T, Guillabert A, D'Haene N, Berton A, De Nadai P, Noel S, Brait M, Franssen JD, Sozzani S, Salmon I, Parmentier M. Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils. J. Immunol. 182: 4974-4984 (2009).

• Dewar JC, Wilkinson J, Wheatley A, Thomas NS, Doull I, Morton N, Lio P, Harvey JF, Liggett SB, Holgate ST, Hall IP. The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families. J. Allergy Clin. Immunol. 100: 261-265 (1997). *

• Dhabhar FS. Enhancing versus suppressive effects of stress on immune function: implications for immunoprotection and immunopathology. Neuroimmunomodulation 16: 300-317 (2009).

• Dhirapong A, Lleo A, Leung P, Gershwin ME, Liu FT. The immunological potential of galectin-1 and -3. Autoimmun. Rev. 8: 360-363 (2009).

• Di Nardo A, Braff MH, Taylor KR, Na C, Granstein RD, McInturff JE, Krutzik S, Modlin RL, Gallo RL. Cathelicidin antimicrobial peptides block dendritic cell TLR4 activation and allergic contact sensitization. J. Immunol. 178: 1829-1834 (2007). *

• Di Paolo MC, Paoluzi OA, Pica R, Iacopini F, Crispino P, Rivera M, Spera G, Paoluzi P. Sulphasalazine and 5-aminosalicylic acid in long-term treatment of ulcerative colitis: report on tolerance and side-effects. Dig. Liver Dis. 33: 563-569 (2001).

• Diakos C, Prieschl EE, Saemann MD, Bohmig GA, Csonga R, Sobanov Y, Baumruker T, Zlabinger GJ. n-Butyrate inhibits Jun NH(2)-terminal kinase activation and cytokine transcription in mast cells. Biochem. Biophys. Res. Commun. 349: 863-868 (2006). *

• Diaz A, Allen JE. Mapping immune response profiles: the emerging scenario from helminth immunology. Eur. J. Immunol. 37: 3319-3326 (2007). *

• Dietert RR, Dewitt J. Developmental immunotoxicity (DIT): the why, when, and how of DIT testing. Methods Mol. Biol. 598: 17-25 (2010). *

• Dinic-Uzurov V, Lalosevic V, Milosevic I, Urosevic I, Lalosevic D, Popovic S. Current differential diagnosis of hypereosinophilic syndrome. Med. Pregl. 60: 581-586 (2007).

• DiScipio RG, Schraufstatter IU. The role of the complement anaphylatoxins in the recruitment of eosinophils. Int. Immunopharmacol. 7: 1909-1923 (2007).

• Dizier MH, Bouzigon E, Guilloud-Bataille M, Betard C, Bousquet J, Charpin D, Gormand F, Hochez J, Just J, Lemainque A, Le Moual N, Matran R, Neukirch F, Oryszczyn MP, Paty E, Pin I, Vervloet D, Kauffmann F, Lathrop M, Demenais F, Annesi-Maesano I. Genome screen in the French EGEA study: detection of linked regions shared or not shared by allergic rhinitis and asthma. Genes Immun. 6: 95-102 (2005). *

• Djukanovic R. The role of co-stimulation in airway inflammation. Clin. Exp. Allergy 30 Suppl. 1: 46-50 (2000).

• Do JS, Park KS, Seo HJ, Kim JH, Hwang JK, Song EJ, Nam SY. Therapeutic target validation of protein kinase C(PKC)-zeta for asthma using a mouse model. Int. J. Mol. Med. 23: 561-566 (2009).

• Dodd JS, Lum E, Goulding J, Muir R, Van Snick J, Openshaw PJ. IL-9 regulates pathology during primary and memory responses to respiratory syncytial virus infection. J. Immunol. 183: 7006-7013 (2009).

• Dodeller F, Schulze-Koops H. The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells. Arthritis Res. Ther. 8: 205 (2006). *

• Doganci A, Eigenbrod T, Krug N, De Sanctis GT, Hausding M, Erpenbeck VJ, Haddad el-B, Lehr HA, Schmitt E, Bopp T, Kallen KJ, Herz U, Schmitt S, Luft C, Hecht O, Hohlfeld JM, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Renz H, et al. The IL-6R alpha chain controls lung CD4+CD25+ Treg development and function during allergic airway inflammation in vivo. J. Clin. Invest. 115: 313-325 (2005). *

• Doganci A, Neurath MF, Finotto S. Mucosal immunoregulation: transcription factors as possible therapeutic targets. Curr. Drug Targets Inflamm. Allergy 4: 565-575 (2005).

• Doggrell SA. Inflammation, the key to much pathology. Highlights from the 7th World Congress on Inflammation, held August 20-24, 2005, in Melbourne, Australia. Timely Top. Med. Cardiovasc. Dis. 10: E4 (2006).

• Doggrell SA. Inflammation, the key to much pathology. Drug News Perspect. 18: 531-539 (2005).

• Dolgachev V, Petersen BC, Budelsky AL, Berlin AA, Lukacs NW. Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease. J. Immunol. 183: 5705-5715 (2009).

• Donald IP, Wilkinson SP. The value of 5-aminosalicylic acid in inflammatory bowel disease for patients intolerant or allergic to sulphasalazine. Postgrad. Med. J. 61: 1047-1048 (1985). *

• Donfack J, Schneider DH, Tan Z, Kurz T, Dubchak I, Frazer KA, Ober C. Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy. Respir. Res. 6: 145 (2005). *

• Dong C. Regulation and pro-inflammatory function of interleukin-17 family cytokines. Immunol. Rev. 226: 80-86 (2008). *

• Dong L, Li H, Wang S, Li Y. Different doses of lipopolysaccharides regulate the lung inflammation of asthmatic mice via TLR4 pathway in alveolar macrophages. J. Asthma 46: 229-233 (2009).

• Donskow-Schmelter K, Jozwicka K, Doligalska M. Nematode infections in mice - an experimental model of immunoregulation. Wiad. Parazytol. 55: 157-166 (2009).

• Douwes J, Le Gros G, Gibson P, Pearce N. Can bacterial endotoxin exposure reverse atopy and atopic disease? J. Allergy Clin. Immunol. 114: 1051-1054 (2004). *

• Driss V, Legrand F, Hermann E, Loiseau S, Guerardel Y, Kremer L, Adam E, Woerly G, Dombrowicz D, Capron M. TLR2-dependent eosinophil interactions with mycobacteria: role of alpha-defensins. Blood 113: 3235-3244 (2009). *

• Duan RS, Link H, Xiao BG. Long-term effects of IFN-gamma, IL-10, and TGF-beta-modulated dendritic cells on immune response in Lewis rats. J. Clin. Immunol. 25: 50-56 (2005). *

• Dubinsky MC. Optimizing immunomodulator therapy for inflammatory bowel disease. Curr. Gastroenterol. Rep. 5: 506-511 (2003).

• Dubois B, Joubert G, de Aguero MG, Gouanvic M, Goubier A, Kaiserlian D. Sequential role of plasmacytoid dendritic cells and regulatory T cells in oral tolerance. Gastroenterology 137: 1019-1028 (2009). *

• Duez C, Gosset P, Tonnel AB. Dendritic cells and Toll-like receptors in allergy and asthma. Eur. J. Dermatol. 16: 12-16 (2006). *

• Dufault R, Schnoll R, Lukiw WJ, Leblanc B, Cornett C, Patrick L, Wallinga D, Gilbert SG, Crider R. Mercury exposure, nutritional deficiencies and metabolic disruptions may affect learning in children. Behav. Brain Funct. 5: 44 (2009).

• Dunford PJ, O'Donnell N, Riley JP, Williams KN, Karlsson L, Thurmond RL. The histamine H4 receptor mediates allergic airway inflammation by regulating the activation of CD4+ T cells. J. Immunol. 176: 7062-7070 (2006). *

• Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, Prescott SL. Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial. J. Allergy Clin. Immunol. 112: 1178-1184 (2003). *

• Dunstan JA, Mori TA, Barden A, Beilin LJ, Taylor AL, Holt PG, Prescott SL. Maternal fish oil supplementation in pregnancy reduces interleukin-13 levels in cord blood of infants at high risk of atopy. Clin. Exp. Allergy 33: 442-448 (2003). *

• Dunstan JA, Prescott SL. Does fish oil supplementation in pregnancy reduce the risk of allergic disease in infants? Curr. Opin. Allergy Clin. Immunol. 5: 215-221 (2005).

• Duran C, Ediger D, Ersoy C, Coskun NF, Selimoglu H, Ercan I, Kiyici S, Guclu M, Saglam DA, Erturk E, Tuncel E, Imamoglu S. Frequency of atopy and allergic disorders among adults with Type 1 diabetes mellitus in the southern Marmara region of Turkey. J. Endocrinol. Invest. 31: 211-215 (2008).

• Durieu I. Cystic fibrosis in adulthood. Rev. Med. Interne. 22 Suppl. 3: 367s-373s (2001).

• Durieu I, Nove Josserand R. Cystic fibrosis in 2008. Rev. Med. Interne. 29: 901-907 (2008).

• Duroudier NP, Tulah AS, Sayers I. Leukotriene pathway genetics and pharmacogenetics in allergy. Allergy 64: 823-839 (2009). *

• Durrant DM, Gaffen SL, Riesenfeld EP, Irvin CG, Metzger DW. Development of allergen-induced airway inflammation in the absence of T-bet regulation is dependent on IL-17. J. Immunol. 183: 5293-5300 (2009).

• Duse M, Caminiti S, Zicari AM. Rhinosinusitis: prevention strategies. Pediatr. Allergy Immunol. 18 Suppl. 18: 71-74 (2007).

• Early SB, Huyett P, Brown-Steinke K, Borish L, Steinke JW. Functional analysis of -351 interleukin-9 promoter polymorphism reveals an activator controlled by NF-kappaB. Genes Immun. 10: 341-349 (2009). *

• Eaton TE, Weiner Miller P, Garrett JE, Cutting GR. Cystic fibrosis transmembrane conductance regulator gene mutations: do they play a role in the aetiology of allergic bronchopulmonary aspergillosis? Clin. Exp. Allergy 32: 756-761 (2002).

• Ebeling C, Lam T, Gordon JR, Hollenberg MD, Vliagoftis H. Proteinase-activated receptor-2 promotes allergic sensitization to an inhaled antigen through a TNF-mediated pathway. J. Immunol. 179: 2910-2917 (2007). *

• Ebringer A, Rashid T, Jawad N, Wilson C, Thompson EJ, Ettelaie C. From rabies to transmissible spongiform encephalopathies: an immune-mediated microbial trigger involving molecular mimicry could be the answer. Med. Hypotheses 68: 113-124 (2007).

• Ebringer A, Rashid T, Wilson C. Bovine spongiform encephalopathy, multiple sclerosis, and Creutzfeldt-Jakob disease are probably autoimmune diseases evoked by acinetobacter bacteria. Ann. N. Y. Acad. Sci. 1050: 417-428 (2005). *

• Edwards LJ, Constantinescu CS. Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases. Inflamm. Allergy Drug Targets 8: 182-190 (2009).

• Edwards LJ, Constantinescu CS. Platelet activating factor/platelet activating factor receptor pathway as a potential therapeutic target in autoimmune diseases. Inflamm. Allergy Drug Targets 8: 182-190 (2009).

• Edwards LJ, Robins RA, Constantinescu CS. Th17/Th1 phenotype in demyelinating disease. Cytokine Dec 31 [Epub ahead of print] (2009).

• Eklund KK. Mast cells in the pathogenesis of rheumatic diseases and as potential targets for anti-rheumatic therapy. Immunol. Rev. 217: 38-52 (2007). *

• El Bakkouri K, Wullaert A, Haegman M, Heyninck K, Beyaert R. Adenoviral gene transfer of the NF-kappa B inhibitory protein ABIN-1 decreases allergic airway inflammation in a murine asthma model. J. Biol. Chem. 280: 17938-17944 (2005). *

• El-Gouhary I, Mohamed A, Suleiman S, Benghuzzi H. Comparison of the amelioration effects of two enzyme inducers on the inflammatory process of experimental allergic encephalitis (EAE) using immunohistochemical technique. Biomed. Sci. Instrum. 41: 376-381 (2005).

• El-Khayat HA, El-Hodhod MA, Abd El-Basset FZ, Tomoum HY, El-Safory HA, Hamdy AM. Rectal bleeding in Egyptian children. Ann. Trop. Paediatr. 26: 337-344 (2006).

• El-Sayed LH, Ghoneim HM, El-Sayed MH, Deimian SR, Adam AN, Abou Rawash SN, Abou Rawash NM, Ursos P. Immunological abnormalities in workers exposed to pollutants at an Egyptian copper company. Immunopharmacol. Immunotoxicol. 25: 473-490 (2003).

• Elenkov IJ. Neurohormonal-cytokine interactions: implications for inflammation, common human diseases and well-being. Neurochem. Int. 52: 40-51 (2008).

• Elenkov IJ, Iezzoni DG, Daly A, Harris AG, Chrousos GP. Cytokine dysregulation, inflammation and well-being. Neuroimmunomodulation 12: 255-269 (2005).

• Elishmereni M, Bachelet I, Levi-Schaffer F. DNAM-1: an amplifier of immune responses as a therapeutic target in various disorders. Curr. Opin. Investig. Drugs 9: 491-496 (2008).

• Elkord E. Role of regulatory T cells in allergy: implications for therapeutic strategy. Inflamm. Allergy Drug Targets 5: 211-217 (2006).

• Elliott AM, Kizza M, Quigley MA, Ndibazza J, Nampijja M, Muhangi L, Morison L, Namujju PB, Muwanga M, Kabatereine N, Whitwortha JA. The impact of helminths on the response to immunization and on the incidence of infection and disease in childhood in Uganda: design of a randomized, double-blind, placebo-controlled, factorial trial of deworming interventions delivered in pregnancy … Clin. Trials 4: 42-57 (2007). *

• Ellmerich S, Mycko M, Takacs K, Waldner H, Wahid FN, Boyton RJ, King RH, Smith PA, Amor S, Herlihy AH, Hewitt RE, Jutton M, Price DA, Hafler DA, Kuchroo VK, Altmann DM. High incidence of spontaneous disease in an HLA-DR15 and TCR transgenic multiple sclerosis model. J. Immunol. 174: 1938-1946 (2005). *

• Ellul P, Vassallo M, Montefort S. Association of asthma and allergic rhinitis with celiac disease. Indian J. Gastroenterol. 24: 270-271 (2005). *

• Emara AM, Abo El-Noor MM, Hassan NA, Wagih AA. Immunotoxicity and hematotoxicity induced by tetrachloroethylene in Egyptian dry cleaning workers. Inhal. Toxicol. Jan 4 [Epub ahead of print] (2010). *

• Engkilde K, Menne T, Johansen JD. Inverse relationship between allergic contact dermatitis and type 1 diabetes mellitus: a retrospective clinic-based study. Diabetologia 49: 644-647 (2006). *

• Engkilde K, Menne T, Johansen JD. Inflammatory bowel disease in relation to contact allergy: a patient-based study. Scand. J. Gastroenterol. 42: 572-576 (2007). *

• Erb KJ. Can helminths or helminth-derived products be used in humans to prevent or treat allergic diseases? Trends Immunol. 30: 75-82 (2009). *

• Erdeljic V, Francetic I, Likic R, Bakran I, Makar-Ausperger K, Simic P. Is referring patients with a positive history of allergic drug reactions or atopy for allergy testing to local anesthetics justified? Methods Find. Exp. Clin. Pharmacol. 31: 177-182 (2009).

• Erkkola M, Kaila M, Nwaru BI, Kronberg-Kippila C, Ahonen S, Nevalainen J, Veijola R, Pekkanen J, Ilonen J, Simell O, Knip M, Virtanen SM. Maternal vitamin D intake during pregnancy is inversely associated with asthma and allergic rhinitis in 5-year-old children. Clin. Exp. Allergy 39: 875-882 (2009). *

• Ertam I, Itirli G, Onay H, Alper S, Ozkinay F. Interleukin-1 receptor antagonist and tumour necrosis factor-alpha gene polymorphisms in Turkish patients with allergic contact dermatitis. Contact Dermatitis 61: 86-90 (2009).

• Eskandari HG, Unal M, Ozturk OG, Vayisoglu Y, Muslu N. Leukotriene C4 synthase A-444C gene polymorphism in patients with allergic rhinitis. Otolaryngol. Head Neck Surg. 134: 997-1000 (2006).

• Esser C, Jux B. Small chemicals, bioactivation, and the immune system - a fragile balance of i-Tox and benefits? Chem. Biodivers. 6: 2138-2143 (2009).

• Estrella C, Rocks N, Paulissen G, Quesada-Calvo F, Noel A, Vilain E, Lassalle P, Tillie-Leblond I, Cataldo D, Gosset P. Role of a disintegrin and metalloprotease-12 in neutrophil recruitment induced by airway epithelium. Am. J. Respir. Cell. Mol. Biol. 41: 449-458 (2009). *

• Ezendam J, de Klerk A, Gremmer ER, van Loveren H. Effects of Bifidobacterium animalis administered during lactation on allergic and autoimmune responses in rodents. Clin. Exp. Immunol. 154: 424-431 (2008). *

• Fabis MJ, Phares TW, Kean RB, Koprowski H, Hooper DC. Blood-brain barrier changes and cell invasion differ between therapeutic immune clearance of neurotrophic virus and CNS autoimmunity. Proc. Natl. Acad. Sci. U.S.A. 105: 15511-15516 (2008). *

• Fabis MJ, Scott GS, Kean RB, Koprowski H, Hooper DC. Loss of blood-brain barrier integrity in the spinal cord is common to experimental allergic encephalomyelitis in knockout mouse models. Proc. Natl. Acad. Sci. U.S.A. 104: 5656-5661 (2007). *

• Fageras Bottcher M, Hmani-Aifa M, Lindstrom A, Jenmalm MC, Mai XM, Nilsson L, Zdolsek HA, Bjorksten B, Soderkvist P, Vaarala O. A TLR4 polymorphism is associated with asthma and reduced lipopolysaccharide-induced interleukin-12(p70) responses in Swedish children. J. Allergy Clin. Immunol. 114: 561-567 (2004). *

• Falcone FH, Loukas A, Quinnell RJ, Pritchard DI. The innate allergenicity of helminth parasites. Clin. Rev. Allergy Immunol. 26: 61-72 (2004). *

• Falcone M, Bloom BR. A T helper cell 2 (Th2) immune response against non-self antigens modifies the cytokine profile of autoimmune T cells and protects against experimental allergic encephalomyelitis. J. Exp. Med. 185: 901-907 (1997). *

• Fallon PG, Mangan NE. Suppression of TH2-type allergic reactions by helminth infection. Nat. Rev. Immunol. 7: 220-230 (2007). *

• Fallon PG, Sasaki T, Sandilands A, Campbell LE, Saunders SP, Mangan NE, Callanan JJ, Kawasaki H, Shiohama A, Kubo A, Sundberg JP, Presland RB, Fleckman P, Shimizu N, Kudoh J, Irvine AD, Amagai M, McLean WH. A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming. Nat. Genet. 41: 602-608 (2009). *

• Fam AG. Difficult gout and new approaches for control of hyperuricemia in the allopurinol-allergic patient. Curr. Rheumatol. Rep. 3: 29-35 (2001).

• Fam AG, Lewtas J, Stein J, Paton TW. Desensitization to allopurinol in patients with gout and cutaneous reactions. Am. J. Med. 93: 299-302 (1992).

• Fang L, Adkins B, Deyev V, Podack ER. Essential role of TNF receptor superfamily 25 (TNFRSF25) in the development of allergic lung inflammation. J. Exp. Med. 205: 1037-1048 (2008). *

• Fang Q, Wang F, Zhao D. Association between regulated upon activation, normal T cells expressed and secreted (RANTES) -28C/G polymorphism and asthma risk - A Meta-Analysis. Int. J. Med. Sci. 7: 55-61 (2010). *

• Fardy JM, Lloyd DA, Reynolds RP. Adverse effects with oral 5-aminosalicyclic acid. J. Clin. Gastroenterol. 10: 635-637 (1988).

• Faria AM, Weiner HL. Oral tolerance: therapeutic implications for autoimmune diseases. Clin. Dev. Immunol. 13: 143-157 (2006). *

• Faulds D, Goa KL, Benfield P. Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs 45: 953-1040 (1993).

• Fecci PE, Ochiai H, Mitchell DA, Grossi PM, Sweeney AE, Archer GE, Cummings T, Allison JP, Bigner DD, Sampson JH. Systemic CTLA-4 blockade ameliorates glioma-induced changes to the CD4+ T cell compartment without affecting regulatory T-cell function. Clin. Cancer Res. 13: 2158-2167 (2007). *

• Fedyk ER, Phipps RP. Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells. Proc. Natl. Acad. Sci. U.S.A. 93: 10978-10983 (1996). *

• Feillet H, Bach JF. Increased incidence of inflammatory bowel disease: the price of the decline of infectious burden? Curr. Opin. Gastroenterol. 20: 560-564 (2004).

• Feleszko W, Jaworska J, Hamelmann E. Toll-like receptors-novel targets in allergic airway disease (probiotics, friends and relatives). Eur. J. Pharmacol. 533: 308-318 (2006). *

• Feltenmark S, Gautam N, Brunnstrom A, Griffiths W, Backman L, Edenius C, Lindbom L, Bjorkholm M, Claesson HE. Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells. Proc. Natl. Acad. Sci. U.S.A. 105: 680-685 (2008). *

• Fernandes B, Plummer A, Wildman M. Duration of intravenous antibiotic therapy in people with cystic fibrosis. Cochrane Database Syst. Rev. 2: CD006682 (2008). *

• Fernandes J, Reshef A, Patton L, Ayuso R, Reese G, Lehrer SB. Immunoglobulin E antibody reactivity to the major shrimp allergen, tropomyosin, in unexposed Orthodox Jews. Clin. Exp. Allergy 33: 956-961 (2003). *

• Ferreira MA. Cytokine expression in allergic inflammation: systematic review of in vivo challenge studies. Mediators Inflamm. 12: 259-267 (2003). *

• Ferrer M. Epidemiology, healthcare, resources, use and clinical features of different types of urticaria. Alergologica 2005. J. Investig. Allergol. Clin. Immunol 19 Suppl. 2: 21-26 (2009).

• Ferrera F, Cava AL, Rizzi M, Hahn BH, Indiveri F, Filaci G. Gene vaccination for the induction of immune tolerance. Ann. N. Y. Acad. Sci. 1110: 99-111 (2007). *

• Feser A, Mahler V. Periorbital dermatitis: causes, differential diagnoses and therapy. J. Dtsch. Dermatol. Ges. Sep 14 [Epub ahead of print] (2009).

• Feser A, Plaza T, Vogelgsang L, Mahler V. Periorbital dermatitis - a recalcitrant disease: causes and differential diagnoses. Br. J. Dermatol. 159: 858-863 (2008). *

• Fina D, Fantini MC, Pallone F, Monteleone G. Role of interleukin-21 in inflammation and allergy. Inflamm. Allergy Drug Targets 6: 63-68 (2007).

• Finkelman FD, Hogan SP, Hershey GK, Rothenberg ME, Wills-Karp M. Importance of cytokines in murine allergic airway disease and human asthma. J. Immunol. 184: 1663-1674 (2010).

• Finotto S. T-cell regulation in asthmatic diseases. Chem. Immunol. Allergy 94: 83-92 (2008).

• Finotto S, Eigenbrod T, Karwot R, Boross I, Doganci A, Ito H, Nishimoto N, Yoshizaki K, Kishimoto T, Rose-John S, Galle PR, Neurath MF. Local blockade of IL-6R signaling induces lung CD4+ T cell apoptosis in a murine model of asthma via regulatory T cells. Int. Immunol. 19: 685-693 (2007). *

• Finotto S, Glimcher L. T cell directives for transcriptional regulation in asthma. Springer Semin. Immunopathol. 25: 281-294 (2004). *

• Fireman E, Masarwy F, Groisman G, Shtark M, Kopelman Y, Kivity S, Fireman Z. Induced sputum eosinophilia in ulcerative colitis patients: the lung as a mirror image of intestine? Respir. Med. 103: 1025-1032 (2009).

• Fischer R, Debbabi H, Dubarry M, Boyaka P, Tome D. Regulation of physiological and pathological Th1 and Th2 responses by lactoferrin. Biochem. Cell. Biol. 84: 303-311 (2006). *

• Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B, Descamps V. A 6-month prospective survey of cutaneous drug reactions in a hospital setting. Br. J. Dermatol. 149: 1018-1022 (2003). *

• Flamant M, Bourreille A. Biologic therapies in inflammatory bowel disease. Rev. Med. Interne. 28: 852-861 (2007).

• Fonacier LS, Dreskin SC, Leung DY. Allergic skin diseases. J. Allergy Clin. Immunol. 125: S138-S149 (2010). *

• Fong DG, Angulo P, Burgart LJ, Lindor KD. Cetirizine-induced cholestasis. J. Clin. Gastroenterol. 31: 250-253 (2000).

• Fontenot AP, Amicosante M. Metal-induced diffuse lung disease. Semin. Respir. Crit. Care Med. 29: 662-669 (2008).

• Forsythe P, Inman MD, Bienenstock J. Oral treatment with live Lactobacillus reuteri inhibits the allergic airway response in mice. Am. J. Respir. Crit. Care Med. 175: 561-569 (2007). *

• Fougerat A, Gayral S, Gourdy P, Schambourg A, Ruckle T, Schwarz MK, Rommel C, Hirsch E, Arnal JF, Salles JP, Perret B, Breton-Douillon M, Wymann MP, Laffargue M. Genetic and pharmacological targeting of phosphoinositide 3-kinase-gamma reduces atherosclerosis and favors plaque stability by modulating inflammatory processes. Circulation 117: 1310-1317 (2008). *

• Fowler AJ, Sheu MY, Schmuth M, Kao J, Fluhr JW, Rhein L, Collins JL, Willson TM, Mangelsdorf DJ, Elias PM, Feingold KR. Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production. J. Invest. Dermatol. 120: 246-255 (2003). *

• Franchimont D, Kino T, Galon J, Meduri GU, Chrousos G. Glucocorticoids and inflammation revisited: the state of the art. NIH clinical staff conference. Neuroimmunomodulation 10: 247-260 (2002).

• Francis JN, Sabroe I, Lloyd CM, Durham SR, Till SJ. Elevated CCR6(+) CD4(+) T lymphocytes in tissue compared with blood and induction of CCL20 during the asthmatic late response. Clin. Exp. Immunol. 152: 440-447 (2008). *

• Fransson M, Benson M, Erjefalt JS, Jansson L, Uddman R, Bjornsson S, Cardell LO, Adner M. Expression of Toll-like receptor 9 in nose, peripheral blood and bone marrow during symptomatic allergic rhinitis. Respir. Res. 8: 17 (2007). *

• Frati F, Moingeon P, Marcucci F, Puccinelli P, Sensi L, Di Cara G, Incorvaia C. Mucosal immunization application to allergic disease: sublingual immunotherapy. Allergy Asthma Proc. 28: 35-39 (2007).

• Frieri M. Identification of masqueraders of autoimmune disease in the office. Allergy Asthma Proc. 24: 421-429 (2003).

• Friese MA, Montalban X, Willcox N, Bell JI, Martin R, Fugger L. The value of animal models for drug development in multiple sclerosis. Brain 129: 1940-1952 (2006). *

• Frisancho-Kiss S, Nyland JF, Davis SE, Barrett MA, Gatewood SJ, Njoku DB, Cihakova D, Silbergeld EK, Rose NR, Fairweather D. Cutting edge: T cell Ig Mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. J. Immunol. 176: 6411-6415 (2006). *

• Frohlich A, Marsland BJ, Sonderegger I, Kurrer M, Hodge MR, Harris NL, Kopf M. IL-21 receptor signaling is integral to the development of Th2 effector responses in vivo. Blood 109: 2023-2031 (2007). *

• Fruhauf P, Lojda Z, Fabianova J, Sedlackova M. Changing clinical image of celiac sprue in childhood. Cas. Lek. Cesk. 145: 470-474 (2006).

• Fujita H, Teng A, Nozawa R, Takamoto-Matsui Y, Katagiri-Matsumura H, Ikezawa Z, Ishii Y. Production of both IL-27 and IFN-gamma after the treatment with a ligand for invariant NK T cells is responsible for the suppression of Th2 response and allergic inflammation in a mouse experimental asthma model. J. Immunol. 183: 254-260 (2009).

• Fujita S, Yamashita N, Ishii Y, Sato Y, Sato K, Eizumi K, Fukaya T, Nozawa R, Takamoto Y, Yamashita N, Taniguchi M, Sato K. Regulatory dendritic cells protect against allergic airway inflammation in a murine asthmatic model. J. Allergy Clin. Immunol. 121: 95-104.e7 (2008).

• Fujiwara M, Hirose K, Kagami S, Takatori H, Wakashin H, Tamachi T, Watanabe N, Saito Y, Iwamoto I, Nakajima H. T-bet inhibits both T(H)2 cell-mediated eosinophil recruitment and T(H)17 cell-mediated neutrophil recruitment into the airways. J. Allergy Clin. Immunol. 119: 662-670 (2007). *

• Fukui N, Honda K, Ito E, Ishikawa K. Peroxisome proliferator-activated receptor-gamma negatively regulates allergic rhinitis in mice. Allergol. Int. 58: 247-253 (2009).

• Fukushima A, Sumi T, Ishida W, Yamada J, Iwakura Y, Ueno H. Endogenous IL-17 does not play a significant role in the development of experimental murine allergic conjunctivitis. Int. Arch. Allergy Immunol. 147: 206-212 (2008).

• Fumagalli M, Pozzoli U, Cagliani R, Comi GP, Riva S, Clerici M, Bresolin N, Sironi M. Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions. J. Exp. Med. 206: 1395-1408 (2009). *

• Furlan R, Cuomo C, Martino G. Animal models of multiple sclerosis. Methods Mol. Biol. 549: 157-173 (2009). *

• Furrie E. Probiotics and allergy. Proc. Nutr. Soc. 64: 465-469 (2005). *

• Furuhjelm C, Warstedt K, Larsson J, Fredriksson M, Bottcher MF, Falth-Magnusson K, Duchen K. Fish oil supplementation in pregnancy and lactation may decrease the risk of infant allergy. Acta Paediatr. 98: 1461-1467 (2009).

• Furuta GT, Nieuwenhuis EE, Karhausen J, Gleich G, Blumberg RS, Lee JJ, Ackerman SJ. Eosinophils alter colonic epithelial barrier function: role for major basic protein. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G890-G897 (2005). *

• Gaisford W, Cooke A. Can infections protect against autoimmunity? Curr. Opin. Rheumatol. 21: 391-396 (2009).

• Gaj F, Crispino P. Proctological surgery: advantages derived from the use of an innovative detergent in the post-operative period. Clin. Ter. 160: 211-213 (2009).

• Galli SJ, Grimbaldeston M, Tsai M. Immunomodulatory mast cells: negative, as well as positive, regulators of immunity. Nat. Rev. Immunol. 8: 478-486 (2008). *

• Galli SJ, Nakae S, Tsai M. Mast cells in the development of adaptive immune responses. Nat. Immunol. 6: 135-142 (2005). *

• Gao L, Tsai YJ, Grigoryev DN, Barnes KC. Host defense genes in asthma and sepsis and the role of the environment. Curr. Opin. Allergy Clin. Immunol. 7: 459-467 (2007).

• Gao N, Qiao HL, Jia LJ, Tian X, Zhang YW. Relationships between specific serum IgE, IgG, IFN-gamma level and IFN-gamma, IFNR1 polymorphisms in patients with penicillin allergy. Eur. J. Clin. Pharmacol. 64: 971-977 (2008). *

• Gao PS, Mathias RA, Plunkett B, Togias A, Barnes KC, Beaty TH, Huang SK. Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population. J. Allergy Clin. Immunol. 115: 982-988 (2005). *

• Garcia-Careaga M Jr, Kerner JA Jr. Gastrointestinal manifestations of food allergies in pediatric patients. Nutr. Clin. Pract. 20: 526-535 (2005). *

• Garcia-Martin E, Garcia-Menaya J, Sanchez B, Martinez C, Rosendo R, Agundez JA. Polymorphisms of histamine-metabolizing enzymes and clinical manifestations of asthma and allergic rhinitis. Clin. Exp. Allergy 37: 1175-1182 (2007). *

• Gariboldi S, Palazzo M, Zanobbio L, Dusio GF, Mauro V, Solimene U, Cardani D, Mantovani M, Rumio C. Low dose oral administration of cytokines for treatment of allergic asthma. Pulm. Pharmacol. Ther. 22: 497-510 (2009).

• Garn H, Mittermann I, Valenta R, Renz H. Autosensitization as a pathomechanism in asthma. Ann. N. Y. Acad. Sci. 1107: 417-425 (2007). *

• Garn H, Renz H. Epidemiological and immunological evidence for the hygiene hypothesis. Immunobiology 212: 441-452 (2007).

• Gasiorowska J, Czerwionka-Szaflarska M. Can obstructive bronchitis be a risk factor of bronchial asthma in infants and small children? Pol. Merkur. Lekarski. 26: 77-81 (2009).

• Gazit V, Tasher D, Hanukoglu A, Landau Z, Ben-Yehuda Y, Somekh E, Dalal I. Atopy in children and adolescents with insulin-dependent diabetes mellitus. Isr. Med. Assoc. J. 10: 858-861 (2008). *

• Gearing AJ. Targeting Toll-like receptors for drug development: a summary of commercial approaches. Immunol. Cell Biol. 85: 490-494 (2007). *

• Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA. Thiopurine drug adverse effects in a population of New Zealand patients with inflammatory bowel disease. Pharmacoepidemiol. Drug Saf. 13: 563-567 (2004). *

• Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA, Roberts RL, Kennedy MA. Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Aliment. Pharmacol. Ther. 18: 395-400 (2003). *

• Gebhardt T, Lorentz A, Detmer F, Trautwein C, Bektas H, Manns MP, Bischoff SC. Growth, phenotype, and function of human intestinal mast cells are tightly regulated by transforming growth factor beta1. Gut 54: 928-934 (2005). *

• Geha RS, Jabara HH, Brodeur SR. The regulation of immunoglobulin E class-switch recombination. Nat. Rev. Immunol. 3: 721-732 (2003). *

• Geiger H, Rudolph KL. Aging in the lympho-hematopoietic stem cell compartment. Trends Immunol. 30: 360-365 (2009). *

• Gerhold K, Avagyan A, Seib C, Frei R, Steinle J, Ahrens B, Dittrich AM, Blumchen K, Lauener R, Hamelmann E. Prenatal initiation of endotoxin airway exposure prevents subsequent allergen-induced sensitization and airway inflammation in mice. J. Allergy Clin. Immunol. 118: 666-673 (2006). *

• Gerosa M, Zimlichman E, Ventura D, Fanelli V, Riboldi P, Meroni PL. Measurement of electrical skin impedance of dermal-visceral zones as a diagnostic tool for disorders of the immune system. Lupus 15: 457-461 (2006).

• Gershwin ME, Incaudo G. Topics in allergy and immunology during pregnancy and early infancy. Clin. Rev. Allergy Immunol. 26: 127-128 (2004).

• Ghigo A, Damilano F, Braccini L, Hirsch E. PI3K inhibition in inflammation: toward tailored therapies for specific diseases. Bioessays 32: 185-196 (2010). *

• Giaffer MH, O'Brien CJ, Holdsworth CD. Clinical tolerance to three 5-aminosalicylic acid releasing preparations in patients with inflammatory bowel disease intolerant or allergic to sulphasalazine. Aliment. Pharmacol. Ther. 6: 51-59 (1992).

• Gibbons DL, Haque SF, Copestake SL, Wells JW, Noble A, Smith AL, Hayday AC. Suppression of airway inflammation by a natural acute infection of the intestinal epithelium. Mucosal Immunol. 2: 144-155 (2009). *

• Gibbons T, Fuchs GJ. Chronic enteropathy: clinical aspects. Nestle Nutr. Workshop Ser. Pediatr. Program 59: 89-104 (2007).

• Gil A, Bengmark S. Advanced glycation and lipoxidation end products - amplifiers of inflammation: the role of food. Nutr. Hosp. 22: 625-640 (2007).

• Gilfillan AM, Tkaczyk C. Integrated signalling pathways for mast-cell activation. Nat. Rev. Immunol. 6: 218-230 (2006). *

• Giorgi PL. Probiotics. A review. Recenti Prog. Med. 100: 40-47 (2009).

• Girodon-Boulandet E, Cazeneuve C, Goossens M. Screening practices for mutations in the CFTR gene ABCC7. Hum. Mutat. 15: 135-149 (2000).

• Girschick HJ, Zimmer C, Klaus G, Darge K, Dick A, Morbach H. Chronic recurrent multifocal osteomyelitis: what is it and how should it be treated? Nat. Clin. Pract. Rheumatol. 3: 733-738 (2007). *

• Glackin L, Leen G, Elnazir B, Greally P. Voriconazole in the treatment of allergic bronchopulmonary aspergillosis in cystic fibrosis. Ir. Med. J. 102: 29 (2009).

• Glaser C, Heinrich J, Koletzko B. Role of FADS1 and FADS2 polymorphisms in polyunsaturated fatty acid metabolism. Metabolism Dec 30 [Epub ahead of print] (2009). *

• Gloria-Bottini F, Bottini N, Renzetti G, Bottini E. ACP1 and Th class of immunological disease: evidence of interaction with gender. Int. Arch. Allergy Immunol. 143: 170-176 (2007).

• Gober MD, Fishelevich R, Zhao Y, Unutmaz D, Gaspari AA. Human natural killer T cells infiltrate into the skin at elicitation sites of allergic contact dermatitis. J. Invest. Dermatol. 128: 1460-1469 (2008). *

• Godoy L. World Immune Regulation Meeting (WIRM) - III: Special focus on regulatory and effector mechanisms. Drug News Perspect. 22: 623-626 (2009).

• Goetzl EJ. Changing paradigms in the immunological science of allergy. Curr. Allergy Asthma Rep. 7: 7-10 (2007).

• Goldman M. Translational mini-review series on Toll-like receptors: Toll-like receptor ligands as novel pharmaceuticals for allergic disorders. Clin. Exp. Immunol. 147: 208-216 (2007). *

• Goldstein MF, Goldstein AL, Dunsky EH, Dvorin DJ, Belecanech GA, Shamir K. Selective IgM immunodeficiency: retrospective analysis of 36 adult patients with review of the literature. Ann. Allergy Asthma Immunol. 97: 717-730 (2006).

• Goldstein MF, Goldstein AL, Dunsky EH, Dvorin DJ, Belecanech GA, Shamir K. Pediatric selective IgM immunodeficiency. Clin. Dev. Immunol. 2008: 624850 (2008). *

• Golec M. Cathelicidin LL-37: LPS-neutralizing, pleiotropic peptide. Ann. Agric. Environ. Med. 14: 1-4 (2007). *

• Gomariz RP, Gutierrez-Canas I, Arranz A, Carrion M, Juarranz Y, Leceta J, Martinez C. Peptides targeting Toll-like receptor signalling pathways for novel immune therapeutics. Curr. Pharm. Des. Dec 23 [Epub ahead of print] (2009).

• Gomez G, Jogie-Brahim S, Shima M, Schwartz LB. Omalizumab reverses the phenotypic and functional effects of IgE-enhanced FcepsilonRI on human skin mast cells. J. Immunol. 179: 1353-1361 (2007). *

• Gonvers JJ, Juillerat P, Mottet C, Felley C, Burnand B, Vader JP, Michetti P, Froehlich F. Maintenance of remission in Crohn's disease. Digestion 71: 41-48 (2005).

• Gonzalez ID, Saeza RS, Rodilla EM, Yges y EL, Toledano FL. Hypersensitivity reactions to chemotherapy drugs. Alergol. Inmunol. Clin. 15: 161-181 (2000). *

• Gonzalez-Huezo M, Ruiz-Mejia R, Rosales-Solís A, Carrillo-Ponce C. Primary sclerosing cholangitis of small ducts, associated with eosinophilic gastroenteritis. Case report and literature review. Rev. Gastroenterol. Mex. 73: 242-246 (2008).

• Gonzalez-Periz A, Claria J. New approaches to the modulation of the cyclooxygenase-2 and 5-lipoxygenase pathways. Curr. Top. Med. Chem. 7: 297-309 (2007).

• Goriely S, Cavoy R, Goldman M. Interleukin-12 family members and type I interferons in Th17-mediated inflammatory disorders. Allergy 64: 702-709 (2009). *

• Gorman S, Judge MA, Burchell JT, Turner DJ, Hart PH. 1,25-Dihydroxyvitamin D(3) enhances the ability of transferred CD4(+) CD25(+) cells to modulate T helper type 2-driven asthmatic responses. Immunology Jan 6 [Epub ahead of print] (2010). *

• Goswami S, Angkasekwinai P, Shan M, Greenlee KJ, Barranco WT, Polikepahad S, Seryshev A, Song LZ, Redding D, Singh B, Sur S, Woodruff P, Dong C, Corry DB, Kheradmand F. Divergent functions for airway epithelial matrix metalloproteinase 7 and retinoic acid in experimental asthma. Nat. Immunol. 10: 496-503 (2009). *

• Gotua M, Lomidze N, Dolidze N, Gotua T. IgE-mediated food hypersensitivity disorders. Georgian Med. News 157: 39-44 (2008).

• Gould HJ, Sutton BJ, Beavil AJ, Beavil RL, McCloskey N, Coker HA, Fear D, Smurthwaite L. The biology of IGE and the basis of allergic disease. Annu. Rev. Immunol. 21: 579-628 (2003). *

• Gould HJ, Takhar P, Harries HE, Durham SR, Corrigan CJ. Germinal-centre reactions in allergic inflammation. Trends Immunol. 27: 446-452 (2006). *

• Gould KA, Strecker TE, Hansen KK, Bynote KK, Peterson KA, Shull JD. Genetic mapping of loci controlling diethylstilbestrol-induced thymic atrophy in the Brown Norway rat. Mamm. Genome 17: 451-464 (2006). *

• Grabbe S, Varga G, Beissert S, Steinert M, Pendl G, Seeliger S, Bloch W, Peters T, Schwarz T, Sunderkotter C, Scharffetter-Kochanek K. Beta2 integrins are required for skin homing of primed T cells but not for priming naive T cells. J. Clin. Invest. 109: 183-192 (2002). *

• Grammatikos AP. The genetic and environmental basis of atopic diseases. Ann. Med. 40: 482-495 (2008).

• Granata F, Nardicchi V, Loffredo S, Frattini A, Ilaria Staiano R, Agostini C, Triggiani M. Secreted phospholipases A(2): a proinflammatory connection between macrophages and mast cells in the human lung. Immunobiology 214: 811-821 (2009).

• Granath A, Hellgren M, Gunnarsson R. Lactose intolerance and long-standing pelvic pain after pregnancy: a case control study. Acta Obstet. Gynecol. Scand. Feb 19 [Epub ahead of print] (2007).

• Granel B, Chevillard C, Dessein A. Interleukin 13 and interleukin 13 receptor involvement in systemic sclerosis. Rev. Med. Interne. 28: 613-622 (2007).

• Granell R, Heron J, Lewis S, Smith GD, Sterne JA, Henderson J. The association between mother and child MTHFR C677T polymorphisms, dietary folate intake and childhood atopy in a population-based, longitudinal birth cohort. Clin. Exp. Allergy 38: 320-328 (2008). *

• Grbovic L, Radenkovic M. Therapeutic use of glucocorticoids and immunosuppressive agents. Srp. Arh. Celok. Lek. 133 Suppl. 1: 67-73 (2005).

• Greco E, Bottini N, Canu G, Maccari AM, Saccucci P, Gloria-Bottini F, Fontana L. Skin testing correlates negatively with high-activity ACP1 *B/*C genotype. Int. Arch. Allergy Immunol. 145: 48-53 (2007).

• Greenberger PA, Yucha CB, Janson S, Huss K. Using rare diseases as models for biobehavioral research: allergic bronchopulmonary aspergillosis. Allergy Asthma Proc. 28: 489-496 (2007).

• Greenfield JR, Tuthill A, Soos MA, Semple RK, Halsall DJ, Chaudhry A, O'Rahilly S. Severe insulin resistance due to anti-insulin antibodies: response to plasma exchange and immunosuppressive therapy. Diabet. Med. 26: 79-82 (2009). *

• Gregory GD, Bickford A, Robbie-Ryan M, Tanzola M, Brown MA. MASTering the immune response: mast cells in autoimmunity. Novartis Found. Symp. 271: 215-225 (2005).

• Grenningloh R, Gho A, di Lucia P, Klaus M, Bollag W, Ho IC, Sinigaglia F, Panina-Bordignon P. Cutting edge: inhibition of the retinoid X receptor (RXR) blocks T helper 2 differentiation and prevents allergic lung inflammation. J. Immunol. 176: 5161-5166 (2006). *

• Grigoriadis N, Tselios T, Deraos S, Orologas A, Deraos G, Matsoukas J, Mavromatis I, Milonas I. Animal models of central nervous system immune-mediated diseases: therapeutic interventions with bioactive peptides and mimetics. Curr. Med. Chem. 12: 1513-1519 (2005).

• Grimbaldeston MA, Nakae S, Kalesnikoff J, Tsai M, Galli SJ. Mast cell-derived interleukin 10 limits skin pathology in contact dermatitis and chronic irradiation with ultraviolet B. Nat. Immunol. 8: 1095-1104 (2007). *

• Groneberg DA, Witt H, Adcock IM, Hansen G, Springer J. Smads as intracellular mediators of airway inflammation. Exp. Lung Res. 30: 223-250 (2004).

• Grulich AE, Vajdic CM. The epidemiology of non-Hodgkin lymphoma. Pathology 37: 409-419 (2005).

• Grzybowska-Chlebowczyk U, Wos H, Sieron AL, Wiecek S, Augusciak-Duma A, Koryciak-Komarska H, Kasznia-Kocot J. Serologic investigations in children with inflammatory bowel disease and food allergy. Mediators Inflamm. 2009: 512695 (2009). *

• Guarner F. Hygiene, microbial diversity and immune regulation. Curr. Opin. Gastroenterol. 23: 667-672 (2007).

• Guillevin L, Pagnoux C. Classification of systemic vasculitides. Rev. Prat. 58: 480-486 (2008).

• Gulen F, Tanac R, Altinoz S, Berdeli A, Zeyrek D, Koksoy H, Demir E. The FcgammaRIIa polymorphism in Turkish children with asthma bronchial and allergic rhinitis. Clin. Biochem. 40: 392-396 (2007). *

• Gunawan B, Kaplowitz N. Clinical perspectives on xenobiotic-induced hepatotoxicity. Drug Metab. Rev. 36: 301-312 (2004). *

• Gundersen RY, Ruud TE, Jorgensen PF, Scholz T, Reinholt FP, Wang JE, Lyngstadaas SP, Aasen AO. Systemic administration of enamel matrix derivative to lipopolysaccharide-challenged pigs: effects on the inflammatory response. Surg. Infect. (Larchmt.) 9: 161-169 (2008).

• Gupta P, Freyschmidt-Paul P, Vitacolonna M, Kiessling S, Hummel S, Hildebrand D, Marhaba R, Zoller M. A chronic contact eczema impedes migration of antigen-presenting cells in alopecia areata. J. Invest. Dermatol. 126: 1559-1573 (2006). *

• Gupta SK, Peters-Golden M, Fitzgerald JF, Croffie JM, Pfefferkorn MD, Molleston JP, Corkins MR, Lim JR. Cysteinyl leukotriene levels in esophageal mucosal biopsies of children with eosinophilic inflammation: are they all the same? Am. J. Gastroenterol. 101: 1125-1128 (2006). *

• Hackett CJ, Dickler HB. Immunologic tolerance for immune system-mediated diseases. J. Allergy Clin. Immunol. 103: 362-370 (1999).

• Haddon DJ, Antignano F, Hughes MR, Blanchet MR, Zbytnuik L, Krystal G, McNagny KM. SHIP1 Is a repressor of mast cell hyperplasia, cytokine production, and allergic inflammation in vivo. J. Immunol. 183: 228-236 (2009).

• Hafen GM, Hartl D, Regamey N, Casaulta C, Latzin P. Allergic bronchopulmonary aspergillosis: the hunt for a diagnostic serological marker in cystic fibrosis patients. Expert Rev. Mol. Diagn. 9: 157-164 (2009).

• Hagel I, Di Prisco MC, Goldblatt J, Le Souef PN. The role of parasites in genetic susceptibility to allergy: IgE, helminthic infection and allergy, and the evolution of the human immune system. Clin. Rev. Allergy Immunol. 26: 75-83 (2004). *

• Hajek AR, Lindley AR, Favoreto S Jr, Carter R, Schleimer RP, Kuperman DA. 12/15-Lipoxygenase deficiency protects mice from allergic airways inflammation and increases secretory IgA levels. J. Allergy Clin. Immunol. 122: 633-639.e3 (2008). *

• Hall MA, McGlinn E, Coakley G, Fisher SA, Boki K, Middleton D, Kaklamani E, Moutsopoulos H, Loughran TP Jr, Ollier WE, Panayi GS, Lanchbury JS. Genetic polymorphism of IL-12 p40 gene in immune-mediated disease. Genes Immun. 1: 219-224 (2000). *

• Hallett JM, Leitch AE, Riley NA, Duffin R, Haslett C, Rossi AG. Novel pharmacological strategies for driving inflammatory cell apoptosis and enhancing the resolution of inflammation. Trends Pharmacol. Sci. 29: 250-257 (2008). *

• Hamelmann E, Herz U, Holt P, Host A, Lauener RP, Matricardi PM, Wahn U, Wickman M. New visions for basic research and primary prevention of pediatric allergy: an iPAC summary and future trends. Pediatr. Allergy Immunol. 19 Suppl. 19: S4-S16 (2008).

• Hammad H, Lambrecht BN. Dendritic cells and epithelial cells: linking innate and adaptive immunity in asthma. Nat. Rev. Immunol. 8: 193-204 (2008). *

• Han D, She W, Zhang L. Association of the CD14 gene polymorphism C-159T with allergic rhinitis. Am. J. Rhinol. Allergy Oct 9 [Epub ahead of print] (2009).

• Han D, She W, Zhang L. Association of the CD14 gene polymorphism C-159T with allergic rhinitis. Am. J. Rhinol. Allergy 24: 1-3 (2010).

• Han JL, Ding RY, Zhao L, Ren Z, Jiang XJ. Rosiglitazone attenuates allergic inflammation and inhibits expression of galectin-3 in a mouse model of allergic rhinitis. J. Int. Med. Res. 36: 830-836 (2008).

• Han MH, Yoon WK, Lee H, Han SB, Lee K, Park SK, Yang KH, Kim HM, Kang JS. Topical application of silymarin reduces chemical-induced irritant contact dermatitis in BALB/c mice. Int. Immunopharmacol. 7: 1651-1658 (2007).

• Hanauer SB. Review article: high-dose aminosalicylates to induce and maintain remissions in ulcerative colitis. Aliment. Pharmacol. Ther. 24 Suppl. 3: 37-40 (2006). *

• Hanauer SB. Update on the etiology, pathogenesis and diagnosis of ulcerative colitis. Nat. Clin. Pract. Gastroenterol. Hepatol. 1: 26-31 (2004). *

• Harada M, Nakashima K, Hirota T, Shimizu M, Doi S, Fujita K, Shirakawa T, Enomoto T, Yoshikawa M, Moriyama H, Matsumoto K, Saito H, Suzuki Y, Nakamura Y, Tamari M. Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma. Am. J. Respir. Cell. Mol. Biol. 36: 491-496 (2007). *

• Harnett MM, Melendez AJ, Harnett W. The therapeutic potential of the filarial nematode-derived immunodulator, ES-62 in inflammatory disease. Clin. Exp. Immunol. Dec 1 [Epub ahead of print] (2009). *

• Harnett W, Harnett MM. Filarial nematode secreted product es-62 is an anti-inflammatory agent: therapeutic potential of small molecule derivatives and ES-62 peptide mimetics. Clin. Exp. Pharmacol. Physiol. 33: 511-518 (2006).

• Harnett W, Harnett MM. Therapeutic immunomodulators from nematode parasites. Expert Rev. Mol. Med. 10: e18 (2008).

• Hartl D. Immunological mechanisms behind the cystic fibrosis-ABPA link. Med. Mycol. 47 Suppl. 1: S183-S191 (2009). *

• Hartl D, Buckland KF, Hogaboam CM. Chemokines in allergic aspergillosis - from animal models to human lung diseases. Inflamm. Allergy Drug Targets 5: 219-228 (2006).

• Hartl D, Koller B, Mehlhorn AT, Reinhardt D, Nicolai T, Schendel DJ, Griese M, Krauss-Etschmann S. Quantitative and functional impairment of pulmonary CD4+CD25hi regulatory T cells in pediatric asthma. J. Allergy Clin. Immunol. 119: 1258-1266 (2007). *

• Harwanegg Ch, Hiller R. Protein microarrays for the diagnosis of allergic diseases: state-of-the-art and future development. Allerg. Immunol. (Paris) 38: 232-236 (2006).

• Hashida R, Ohkura N, Saito H, Tsujimoto G. The NR4A nuclear receptor family in eosinophils. J. Hum. Genet. 52: 13-20 (2007). *

• Hashimoto K, Sheller JR, Morrow JD, Collins RD, Goleniewska K, O'Neal J, Zhou W, Ji S, Mitchell DB, Graham BS, Peebles RS Jr. Cyclooxygenase inhibition augments allergic inflammation through CD4-dependent, STAT6-independent mechanisms. J. Immunol. 174: 525-532 (2005). *

• Hashimoto T, Kobayashi N, Kajiyama Y, Kaminuma O, Suko M, Mori A. IL-2-induced IL-13 production by allergen-specific human helper T cell clones. Int. Arch. Allergy Immunol. 140 Suppl. 1: 51-54 (2006).

• Hasko G, Pacher P. A2A receptors in inflammation and injury: lessons learned from transgenic animals. J. Leukoc. Biol. 83: 447-455 (2008). *

• Hatano Y, Man MQ, Uchida Y, Crumrine D, Mauro TM, Feingold KR, Elias PM, Holleran WM. Murine atopic dermatitis responds to peroxisome proliferator-activated receptors alpha and beta/delta (but not gamma) and liver X receptor activators. J. Allergy Clin. Immunol. Oct 7 [Epub ahead of print] (2009). *

• Hauff K, Zamzow C, Law WJ, De Melo J, Kennedy K, Los M. Peptide-based approaches to treat asthma, arthritis, other autoimmune diseases and pathologies of the central nervous system. Arch. Immunol. Ther. Exp. (Warsz.) 53: 308-320 (2005).

• Hautekeete ML, Horsmans Y, Van Waeyenberge C, Demanet C, Henrion J, Verbist L, Brenard R, Sempoux C, Michielsen PP, Yap PS, Rahier J, Geubel AP. HLA association of amoxicillin-clavulanate-induced hepatitis. Gastroenterology 117: 1181-1186 (1999). *

• Hawk J. Benign summer light eruption and polymorphic light eruption: genetic and functional studies suggest that a revised nomenclature is required. J. Cosmet. Dermatol. 3: 173-175 (2004).

• Haworth O, Cernadas M, Yang R, Serhan CN, Levy BD. Resolvin E1 regulates interleukin 23, interferon-gamma and lipoxin A(4) to promote the resolution of allergic airway inflammation. Nat. Immunol. 9: 873-879 (2008). *

• Hawrylowicz CM, O'Garra A. Potential role of interleukin-10-secreting regulatory T cells in allergy and asthma. Nat. Rev. Immunol. 5: 271-283 (2005). *

• Hayashi K, Altman A. Protein kinase C theta (PKCtheta): a key player in T cell life and death. Pharmacol. Res. 55: 537-544 (2007). *

• Hayashi R, Wada H, Ito K, Adcock IM. Effects of glucocorticoids on gene transcription. Eur. J. Pharmacol. 500: 51-62 (2004). *

• Hayashi T, Beck L, Rossetto C, Gong X, Takikawa O, Takabayashi K, Broide DH, Carson DA, Raz E. Inhibition of experimental asthma by indoleamine 2,3-dioxygenase. J. Clin. Invest. 114: 270-279 (2004). *

• Hayashi T, Gray CS, Chan M, Tawatao RI, Ronacher L, McGargill MA, Datta SK, Carson DA, Corr M. Prevention of autoimmune disease by induction of tolerance to Toll-like receptor 7. Proc. Natl. Acad. Sci. U.S.A. 106: 2764-2769 (2009). *

• Hayashi T, Raz E. TLR9-based immunotherapy for allergic disease. Am. J. Med. 119: 897.e1-6 (2006). *

• Hazebrouck S, Przybylski-Nicaise L, Ah-Leung S, Adel-Patient K, Corthier G, Langella P, Wal JM. Influence of the route of administration on immunomodulatory properties of bovine beta-lactoglobulin-producing Lactobacillus casei. Vaccine 27: 5800-5805 (2009).

• He R, Kim HY, Yoon J, Oyoshi MK, Macginnitie A, Goya S, Freyschmidt EJ, Bryce P, McKenzie AN, Umetsu DT, Oettgen HC, Geha RS. Exaggerated IL-17 response to epicutaneous sensitization mediates airway inflammation in the absence of IL-4 and IL-13. J. Allergy Clin. Immunol. 124: 761-770.e1 (2009). *

• He R, Oyoshi MK, Jin H, Geha RS. Epicutaneous antigen exposure induces a Th17 response that drives airway inflammation after inhalation challenge. Proc. Natl. Acad. Sci. U.S.A. 40: 15817-15822 (2007). *

• He SH. Key role of mast cells and their major secretory products in inflammatory bowel disease. World J. Gastroenterol. 10: 309-318 (2004). *

• Headley MB, Zhou B, Shih WX, Aye T, Comeau MR, Ziegler SF. TSLP conditions the lung immune environment for the generation of pathogenic innate and antigen-specific adaptive immune responses. J. Immunol. 182: 1641-1647 (2009).

• Hedley ML. Gene therapy of chronic inflammatory disease. Adv. Drug Deliv. Rev. 44: 195-207 (2000).

• Heib V, Becker M, Taube C, Stassen M. Advances in the understanding of mast cell function. Br. J. Haematol. 142: 683-694 (2008). *

• Heine G, Dahten A, Hilt K, Ernst D, Milovanovic M, Hartmann B, Worm M. Liver X receptors control IgE expression in B cells. J. Immunol. 182: 5276-5282 (2009).

• Heine G, Niesner U, Chang HD, Steinmeyer A, Zugel U, Zuberbier T, Radbruch A, Worm M. 1,25-Dihydroxyvitamin D(3) promotes IL-10 production in human B cells. Eur. J. Immunol. 38: 2210-2218 (2008). *

• Heine H, Lien E. Toll-like receptors and their function in innate and adaptive immunity. Int. Arch. Allergy Immunol. 130: 180-192 (2003).

• Heine RG, Tang ML. Dietary approaches to the prevention of food allergy. Curr. Opin. Clin. Nutr. Metab. Care 11: 320-328 (2008).

• Heinrich S, Hartl D, Griese M. Surfactant protein a - from genes to human lung diseases. Curr. Med. Chem. 13: 3239-3252 (2006).

• Heinzmann A, Plesnar C, Kuehr J, Forster J, Deichmann KA. Common polymorphisms in the CTLA-4 and CD28 genes at 2q33 are not associated with asthma or atopy. Eur. J. Immunogenet. 27: 57-61 (2000). *

• Hellings PW, Vandenberghe P, Kasran A, Coorevits L, Overbergh L, Mathieu C, Ceuppens JL. Blockade of CTLA-4 enhances allergic sensitization and eosinophilic airway inflammation in genetically predisposed mice. Eur. J. Immunol. 32: 585-594 (2002). *

• Helliwell C. Immunology primer. Immunology news: a new type of T cell is discovered (http://www.acnr.co.uk/JF07/ACNR_JF07_immunology.pdf). ACNR 6: 8-9 (2007). *

• Hemdan NY, Emmrich F, Faber S, Lehmann J, Sack U. Alterations of TH1/TH2 reactivity by heavy metals: possible consequences include induction of autoimmune diseases. Ann. N. Y. Acad. Sci. 1109: 129-137 (2007). *

• Henckaerts L, Vermeire S. NOD2/CARD15 disease associations other than Crohn's disease. Inflamm. Bowel Dis. 13: 235-241 (2007). *

• Heratizadeh A, Werfel T, Kapp A. Atopic dermatitis: the hygiene hypothesis: prevention through helminth infections? Hautarzt. 57: 576, 578-585 (2006).

• Hermon-Taylor J. Mycobacterium avium subspecies paratuberculosis in the causation of Crohn's disease. World J. Gastroenterol. 6: 630-632 (2000). *

• Hernell O, West C. Do we need personalized recommendations for infants at risk of developing disease? Nestle Nutr. Workshop Ser. Pediatr. Program 62: 239-252 (2008).

• Herrick CA, Bottomly K. To respond or not to respond: T cells in allergic asthma. Nat. Rev. Immunol. 3: 405-412 (2003). *

• Hersoug LG, Linneberg A. The link between the epidemics of obesity and allergic diseases: does obesity induce decreased immune tolerance? Allergy 62: 1205-1213 (2007). *

• Himmerich H, Fulda S, Linseisen J, Seiler H, Wolfram G, Himmerich S, Gedrich K, Kloiber S, Lucae S, Ising M, Uhr M, Holsboer F, Pollmacher T. Depression, comorbidities and the TNF-alpha system. Eur. Psychiatry 23: 421-429 (2008).

• Hino A, Kweon MN, Fujihashi K, McGhee JR, Kiyono H. Pathological role of large intestinal IL-12p40 for the induction of Th2-type allergic diarrhea. Am. J. Pathol. 164: 1327-1335 (2004). *

• Hintermann E, Christen U. Viral infection - a cure for type 1 diabetes? Curr. Med. Chem. 14: 2048-2052 (2007).

• Hirabayashi A, Mukaiyama H, Kobayashi H, Shiohara H, Nakayama S, Ozawa M, Tsuji E, Miyazawa K, Misawa K, Ohnota H, Isaji M. Structure-activity relationship studies of imidazo[1,2-c]pyrimidine derivatives as potent and orally effective Syk family kinases inhibitors. Bioorg. Med. Chem. 16: 9247-9260 (2008). *

• Hirano M, Davis RS, Fine WD, Nakamura S, Shimizu K, Yagi H, Kato K, Stephan RP, Cooper MD. IgE(b) immune complexes activate macrophages through FcgammaRIV binding. Nat. Immunol. 8: 762-771 (2007). *

• Hirota K, Martin B, Veldhoen M. Development, regulation and functional capacities of Th17 cells. Semin. Immunopathol. Jan 27 [Epub ahead of print] (2010). *

• Hirota SA, Beck PL, Macdonald JA. Targeting hypoxia-inducible factor-1 (HIF-1) signaling in therapeutics: implications for the treatment of inflammatory bowel disease. Recent Pat. Inflamm. Allergy Drug Discov. 3: 1-16 (2009).

• Hirota T, Suzuki Y, Hasegawa K, Obara K, Matsuda A, Akahoshi M, Nakashima K, Cheng L, Takahashi N, Shimizu M, Doi S, Fujita K, Enomoto T, Ebisawa M, Yoshihara S, Nakamura Y, Kishi F, Shirakawa T, Tamari M. Functional haplotypes of IL-12B are associated with childhood atopic asthma. J. Allergy Clin. Immunol. 116: 789-795 (2005). *

• Hisada T, Ishizuka T, Aoki H, Mori M. Resolvin E1 as a novel agent for the treatment of asthma. Expert Opin. Ther. Targets 13: 513-522 (2009).

• Hizawa N, Kawaguchi M, Huang SK, Nishimura M. Role of interleukin-17F in chronic inflammatory and allergic lung disease. Clin. Exp. Allergy 36: 1109-1114 (2006). *

• Ho SH, Lee HJ, Kim DS, Jeong JG, Kim S, Yu SS, Jin Z, Kim S, Kim JM. Intrasplenic electro-transfer of IL-4 encoding plasmid DNA efficiently inhibits rat experimental allergic encephalomyelitis. Biochem. Biophys. Res. Commun. 343: 816-824 (2006). *

• Hoarau C, Lagaraine C, Martin L, Velge-Roussel F, Lebranchu Y. Supernatant of Bifidobacterium breve induces dendritic cell maturation, activation, and survival through a Toll-like receptor 2 pathway. J. Allergy Clin. Immunol. 117: 696-702 (2006). *

• Hoff S, Seiler H, Heinrich J, Kompauer I, Nieters A, Becker N, Nagel G, Gedrich K, Karg G, Wolfram G, Linseisen J. Allergic sensitisation and allergic rhinitis are associated with n-3 polyunsaturated fatty acids in the diet and in red blood cell membranes. Eur. J. Clin. Nutr. 59: 1071-1080 (2005). *

• Hoffjan S, Epplen JT. The genetics of atopic dermatitis: recent findings and future options. J. Mol. Med. 83: 682-692 (2005). *

• Hoffjan S, Ostrovnaja I, Nicolae D, Newman DL, Nicolae R, Gangnon R, Steiner L, Walker K, Reynolds R, Greene D, Mirel D, Gern JE, Lemanske RF Jr, Ober C. Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy. J. Allergy Clin. Immunol. 113: 511-518 (2004). *

• Hoffjan S, Parwez Q, Petrasch-Parwez E, Stemmler S. Variation in the BDNF and NGFB genes in German atopic dermatitis patients. Mol. Cell. Probes 23: 35-38 (2009).

• Hoffjan S, Stemmler S, Parwez Q, Petrasch-Parwez E, Arinir U, Rhode G, Reinitz-Rademacher K, Schultze-Werninghaus G, Bufe A, Epplen JT. Evaluation of the Toll-like receptor 6 Ser249Pro polymorphism in patients with asthma, atopic dermatitis and chronic obstructive pulmonary disease. BMC Med. Genet. 6: 34 (2005). *

• Hofmann AM, Abraham SN. New roles for mast cells in modulating allergic reactions and immunity against pathogens. Curr. Opin. Immunol. 21: 679-686 (2009).

• Hofstetter HH, Toyka KV, Gold R. Permanent effector phenotype of neuroantigen-specific T cells acquired in the central nervous system during experimental allergic encephalomyelitis. Neurosci. Lett. 391: 127-130 (2006). *

• Hogaboam CM, Carpenter KJ, Schuh JM, Buckland KF. Aspergillus and asthma - any link? Med. Mycol. 43 Suppl. 1: S197-S202 (2005).

• Hogaboam CM, Takahashi K, Ezekowitz RA, Kunkel SL, Schuh JM. Mannose-binding lectin deficiency alters the development of fungal asthma: effects on airway response, inflammation, and cytokine profile. J. Leukoc. Biol. 75: 805-814 (2004). *

• Hogan SP, Rothenberg ME. Review article: the eosinophil as a therapeutic target in gastrointestinal disease. Aliment. Pharmacol. Ther. 20: 1231-1240 (2004). *

• Holgate ST. The epithelium takes centre stage in asthma and atopic dermatitis. Trends Immunol. 28: 248-251 (2007). *

• Holgate ST. Genetic common ground between allergic and autoimmune disease: the role of cytotoxic T-lymphocyte antigen 4. J. Allergy Clin. Immunol. 114: 277-279 (2004). *

• Holgate ST. Pathogenesis of asthma. Clin. Exp. Allergy 38: 872-897 (2008). *

• Holgate ST, Davies DE. Rethinking the pathogenesis of asthma. Immunity 31: 362-367 (2009). *

• Holgate ST, Polosa R. Treatment strategies for allergy and asthma. Nat. Rev. Immunol. 8: 218-230 (2008). *

• Holla LI, Mrazek F, Petrek M. MCP-1 and CCR2 gene polymorphisms in Czech patients with allergic disorders. Int. J. Immunogenet. 36: 69-72 (2009). *

• Homey B, Alenius H, Muller A, Soto H, Bowman EP, Yuan W, McEvoy L, Lauerma AI, Assmann T, Bunemann E, Lehto M, Wolff H, Yen D, Marxhausen H, To W, Sedgwick J, Ruzicka T, Lehmann P, Zlotnik A. CCL27-CCR10 interactions regulate T cell-mediated skin inflammation. Nat. Med. 8: 157-165 (2002). *

• Honda T, Matsuoka T, Ueta M, Kabashima K, Miyachi Y, Narumiya S. Prostaglandin E(2)-EP(3) signaling suppresses skin inflammation in murine contact hypersensitivity. J. Allergy Clin. Immunol. 124: 809-818.e2 (2009). *

• Hong X, Tsai HJ, Wang X. Genetics of food allergy. Curr. Opin. Pediatr. 21: 770-776 (2009).

• Hopner S, Dickhaut K, Hofstatter M, Kramer H, Ruckerl D, Soderhall JA, Gupta S, Marin-Esteban V, Kuhne R, Freund C, Jung G, Falk K, Rotzschke O. Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket. J. Biol. Chem. 281: 38535-38542 (2006). *

• Horiuchi K, Kakizaki S, Kosone T, Ichikawa T, Sato K, Takagi H, Mori M, Sakurai S, Fukusato T. Marked eosinophilia as the first manifestation of sclerosing cholangitis. Intern. Med. 48: 1377-1382 (2009). *

• Horner AA. Update on Toll-like receptor ligands and allergy: implications for immunotherapy. Curr. Allergy Asthma Rep. 6: 395-401 (2006).

• Horner AA. Toll-like receptor ligands and atopy: a coin with at least two sides. J. Allergy Clin. Immunol. 117: 1133-1140 (2006). *

• Horsmans Y, Harvengt C. Secondary drug-induced cholestasis with bile duct involvement. Acta Gastroenterol. Belg. 54: 27-33 (1991).

• Hoskison TK, Wortmann RL. Advances in the management of gout and hyperuricaemia. Scand. J. Rheumatol. 35: 251-260 (2006). *

• Hosseini-Farahabadi S, Tavakkol-Afshari J, Rafatpanah H, Farid Hosseini R, Khaje Daluei M. Association between the polymorphisms of IL-4 gene promoter (-590C>T), IL-13 coding region (R130Q) and IL-16 gene promoter (-295T>C) and allergic asthma. Iran. J. Allergy Asthma Immunol. 6: 9-14 (2007).

• Hossny EM, Amr NH, Elsayed SB, Nasr RA, Ibraheim EM. Association of polymorphisms in the mast cell chymase gene promoter region (-1903 g/A) and (TG)n(GA)m repeat downstream of the gene with bronchial asthma in children. J. Investig. Allergol. Clin. Immunol. 18: 376-381 (2008). *

• Howard TD, Meyers DA, Bleecker ER. Mapping susceptibility genes for asthma and allergy. J. Allergy Clin. Immunol. 105: S477-S481 (2000).

• Hrdlickova B, Izakovicova-Holla L. Association of single nucleotide polymorphisms in the eosinophil peroxidase gene with allergic rhinitis in the Czech population. Int. Arch. Allergy Immunol. 150: 184-191 (2009).

• Hsu SC, Chen LC, Kuo ML, Huang JL, Huang SK. Novel SNPs in a candidate gene, CRTH2, for allergic diseases. Genes Immun. 3: 114-116 (2002). *

• Hu L, Edamatsu H, Takenaka N, Ikuta S, Kataoka T. Crucial role of phospholipase Cvarepsilon in induction of local skin inflammatory reactions in the elicitation stage of allergic contact hypersensitivity. J. Immunol. 184: 993-1002 (2010).

• Hu ZQ, Zhao WH, Shimamura T. Regulation of mast cell development by inflammatory factors. Curr. Med. Chem. 14: 3044-3050 (2007). *

• Huang H, Peng Y, Liu F, Lei H. Is IgA nephropathy induced by abnormalities of CD4(+)CD25(+)Treg cells in the tonsils? Med. Hypotheses 69: 410-413 (2007).

• Huang JF, Thurmond RL. The new biology of histamine receptors. Curr. Allergy Asthma Rep. 8: 21-27 (2008).

• Huang MT, Dai YS, Chou YB, Juan YH, Wang CC, Chiang BL. Regulatory T cells negatively regulate neovasculature of airway remodeling via DLL4-Notch signaling. J. Immunol. 183: 4745-4754 (2009).

• Hubeau C, Apostolou I, Kobzik L. Targeting of CD25 and glucocorticoid-induced TNF receptor family-related gene-expressing T cells differentially modulates asthma risk in offspring of asthmatic and normal mother mice. J. Immunol. 178: 1477-1487 (2007). *

• Hudson TJ. Skin barrier function and allergic risk. Nat. Genet. 38: 399-400 (2006). *

• Huibregtse IL, Snoeck V, de Creus A, Braat H, De Jong EC, Van Deventer SJ, Rottiers P. Induction of ovalbumin-specific tolerance by oral administration of Lactococcus lactis secreting ovalbumin. Gastroenterology 133: 517-528 (2007). *

• Humbert M, Garcia G, Chanez P. Targeted immunologic therapies for severe asthma. Presse. Med. 37: 173-181 (2008).

• Humbert P, Pelletier F, Dreno B, Puzenat E, Aubin F. Gluten intolerance and skin diseases. Eur. J. Dermatol. 16: 4-11 (2006).

• Huppmann MV, Monson M. Allergic bronchopulmonary aspergillosis: a unique presentation in a pediatric patient. Pediatr. Radiol. 38: 879-883 (2008). *

• Hurst SD, Muchamuel T, Gorman DM, Gilbert JM, Clifford T, Kwan S, Menon S, Seymour B, Jackson C, Kung TT, Brieland JK, Zurawski SM, Chapman RW, Zurawski G, Coffman RL. New IL-17 family members promote Th1 or Th2 responses in the lung: in vivo function of the novel cytokine IL-25. J. Immunol. 169: 443-453 (2002). *

• Hussain I, Kline JN. DNA, the immune system, and atopic disease. J. Investig. Dermatol. Symp. Proc. 9: 23-28 (2004). *

• Hussein YM, Ahmad AS, Ibrahem MM, El Tarhouny SA, Shalaby SM, Elshal AS, El Said M. Interferon gamma gene polymorphism as a biochemical marker in Egyptian atopic patients. J. Investig. Allergol. Clin. Immunol. 19: 292-298 (2009).

• Hutchison S, Choo-Kang BS, Bundick RV, Leishman AJ, Brewer JM, McInnes IB, Garside P. Tumour necrosis factor-alpha blockade suppresses murine allergic airways inflammation. Clin. Exp. Immunol. 151: 114-122 (2008). *

• Huurre A, Laitinen K, Rautava S, Korkeamaki M, Isolauri E. Impact of maternal atopy and probiotic supplementation during pregnancy on infant sensitization: a double-blind placebo-controlled study. Clin. Exp. Allergy 38: 1342-1348 (2008). *

• Hwang I, Cha A, Lee H, Yoon H, Yoon T, Cho B, Lee S, Park Y. n-3 Polyunsaturated fatty acids and atopy in Korean preschoolers. Lipids 42: 345-349 (2007).

• Iakhiaev MA, Iakhiaev AV. Graph-theoretical comparison of protein surfaces reveals potential determinants of cross-reactivity and the molecular mimicry. Mol. Immunol. Nov 23 [Epub ahead of print] (2009). *

• Ichikawa S, Fujii R, Fujiwara D, Komiyama Y, Kaisho T, Sakaguchi M, Konishi Y. MyD88 but not TLR2, 4 or 9 is essential for IL-12 induction by lactic acid bacteria. Biosci. Biotechnol. Biochem. 71: 3026-3032 (2007). *

• Ichikawa Y, Saito T, Yamanaka H, Akizuki M, Kondo H, Kobayashi S, Oshima H, Kawai S, Hama N, Yamada H, Mimori T, Amano K, Tanaka Y, Matsuoka Y, Yamamoto S, Matsubara T, Murata N, Asai T, Suzuki Y; MTX-BUC Combination Study Group. Therapeutic effects of the combination of methotrexate and bucillamine in early rheumatoid arthritis: a multicenter, double-blind, randomized controlled study. Mod. Rheumatol. 15: 323-328 (2005).

• Igawa K, Satoh T, Hirashima M, Yokozeki H. Regulatory mechanisms of galectin-9 and eotaxin-3 synthesis in epidermal keratinocytes: possible involvement of galectin-9 in dermal eosinophilia of Th1-polarized skin inflammation. Allergy 61: 1385-1391 (2006). *

• Iglesias Alzueta J, Matamoros Florí N. Common variable immunodeficiency. Review. Allergol. Immunopathol. (Madr.) 29: 113-118 (2001).

• Iguchi T, Kawata A, Watanabe T, Mazumder TK, Tanabe S. Fermented barley extract suppresses the development of atopic dermatitis-like skin lesions in NC/Nga mice, probably by inhibiting inflammatory cytokines. Biosci. Biotechnol. Biochem. 73: 489-493 (2009). *

• Iikura M, Suto H, Kajiwara N, Oboki K, Ohno T, Okayama Y, Saito H, Galli SJ, Nakae S. IL-33 can promote survival, adhesion and cytokine production in human mast cells. Lab. Invest. 87: 971-978 (2007). *

• Ikeda H, Inao M, Fujiwara K. Inhibitory effect of tranilast on activation and transforming growth factor beta 1 expression in cultured rat stellate cells. Biochem. Biophys. Res. Commun. 227: 322-327 (1996). *

• Ikeuchi Y, Kobayashi Y, Arakawa H, Suzuki M, Tamra K, Morikawa A. Polymorphisms in interleukin-4-related genes in patients with minimal change nephrotic syndrome. Pediatr. Nephrol. 24: 489-495 (2009).

• Imamura M, Okunishi K, Ohtsu H, Nakagome K, Harada H, Tanaka R, Yamamoto K, Dohi M. Pravastatin attenuates allergic airway inflammation by suppressing antigen-sensitization, IL-17 production, and antigen-presentation in the lung. Thorax 64: 44-49 (2009).

• Immonen AK, Taivainen AH, Narvanen AT, Kinnunen TT, Saarelainen SA, Rytkonen-Nissinen MA, Virtanen TI. Use of multiple peptides containing T cell epitopes is a feasible approach for peptide-based immunotherapy in Can f 1 allergy. Immunology 120: 38-46 (2007). *

• Inadera H. The immune system as a target for environmental chemicals: xenoestrogens and other compounds. Toxicol. Lett. 164: 191-206 (2006). *

• Incorvaia C, Frati F, Puccinelli P, Marcucci F, Di Cara G, Sensi L, Scurati S, Yacoub MR, Moingeon P. Effects of sublingual immunotherapy on allergic inflammation. Inflamm. Allergy Drug Targets 7: 167-172 (2008).

• Incorvaia C, Frati F, Verna N, D'Alo S, Motolese A, Pucci S. Allergy and the skin. Clin. Exp. Immunol. 153 Suppl. 1: 27-29 (2008). *

• Irie T, Maeda Y, Aida T, Sumitani K, Nagumo M, Tachikawa T. Multiple granulomatous inflammation in the minor salivary glands: a proposed new entity, allergic granulomatous sialadenitis. Pathol. Int. 54: 850-853 (2004). *

• Irinyi B, Szeles G, Gyimesi E, Tumpek J, Heredi E, Dimitrios G, Adany R, Hunyadi J, Szegedi A. Clinical and laboratory examinations in the subgroups of chronic urticaria. Int. Arch. Allergy Immunol. 144: 217-225 (2007).

• Ishigame H, Kakuta S, Nagai T, Kadoki M, Nambu A, Komiyama Y, Fujikado N, Tanahashi Y, Akitsu A, Kotaki H, Sudo K, Nakae S, Sasakawa C, Iwakura Y. Differential roles of interleukin-17A and -17F in host defense against mucoepithelial bacterial infection and allergic responses. Immunity 30: 108-119 (2009). *

• Ishihara K, Hirano T. IL-6 in autoimmune disease and chronic inflammatory proliferative disease. Cytokine Growth Factor Rev. 13: 357-368 (2002).

• Isolauri E, Ouwehand AC, Laitinen K. Novel approaches to the nutritional management of the allergic infant. Acta Paediatr. Suppl. 94: 110-114 (2005).

• Itoh S, Nakae S, Axtell RC, Velotta JB, Kimura N, Kajiwara N, Iwakura Y, Saito H, Adachi H, Steinman L, Robbins RC, Fischbein MP. IL-17 contributes to the development of chronic rejection in a murine heart transplant model. J. Clin. Immunol. Feb 4 [Epub ahead of print] (2010). *

• Ivanciuc O, Schein CH, Braun W. Data mining of sequences and 3D structures of allergenic proteins. Bioinformatics 18: 1358-1364 (2002). *

• Iwakura Y, Nakae S, Saijo S, Ishigame H. The roles of IL-17A in inflammatory immune responses and host defense against pathogens. Immunol. Rev. 226: 57-79 (2008). *

• Iwamura C, Nakayama T. Toll-like receptors in the respiratory system: their roles in inflammation. Curr. Allergy Asthma Rep. 8: 7-13 (2008).

• Jackson WB. Management of dysfunctional tear syndrome: a Canadian consensus. Can. J. Ophthalmol. 44: 385-394 (2009). *

• Jacobson KA, Klutz AM, Tosh DK, Ivanov AA, Preti D, Baraldi PG. Medicinal chemistry of the A(3) adenosine receptor: agonists, antagonists, and receptor engineering. Handb. Exp. Pharmacol. 193: 123-159 (2009).

• Jahn-Schmid B, Sirven P, Leb V, Pickl WF, Fischer GF, Gadermaier G, Egger M, Ebner C, Ferreira F, Maillere B, Bohle B. Characterization of HLA class II/peptide-TCR interactions of the immunodominant T cell epitope in Art v 1, the major mugwort pollen allergen. J. Immunol. 181: 3636-3642 (2008). *

• Jana M, Pahan K. Induction of lymphotoxin-alpha by interleukin-12 p40 homodimer, the so-called biologically inactive molecule, but not IL-12 p70. Immunology 127: 312-325 (2009). *

• Jang N, Stewart G, Jones G. Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis. Genes Immun. 6: 262-264 (2005). *

• Janssen R, Bont L, Siezen CL, Hodemaekers HM, Ermers MJ, Doornbos G, Slot R, Wijmenga C, Goeman JJ, Kimpen JL, van Houwelingen HC, Kimman TG, Hoebee B. Genetic susceptibility to respiratory syncytial virus bronchiolitis is predominantly associated with innate immune genes. J. Infect. Dis. 196: 826-834 (2007). *

• Japiassu AM, Salluh JI, Bozza PT, Bozza FA, Castro-Faria-Neto HC. Revisiting steroid treatment for septic shock: molecular actions and clinical effects - a review. Mem. Inst. Oswaldo Cruz 104: 531-548 (2009). *

• Jaradat M, Stapleton C, Tilley SL, Dixon D, Erikson CJ, McCaskill JG, Kang HS, Angers M, Liao G, Collins J, Grissom S, Jetten AM. Modulatory role for retinoid-related orphan receptor alpha in allergen-induced lung inflammation. Am. J. Respir. Crit. Care Med. 174: 1299-1309 (2006). *

• Jasek M, Luszczek W, Obojski A, Winiarska B, Halubek K, Nowak I, Manczak M, Wisniewski A, Pawlik A, Jonkisz A, Lebioda A, Majorczyk E, Dobosz T, Kusnierczyk P. Distribution of CTLA-4 polymorphisms in allergic asthma. Int. Arch. Allergy Immunol. 141: 223-229 (2006).

• Jaskiewicz E. Epitopes on myelin proteins recognized by autoantibodies present in multiple sclerosis patients. Postepy. Hig. Med. Dosw. (Online) 58: 472-482 (2004).

• Jaspars EH. The immune system of the skin and stereotyped reaction patterns in inflammatory skin diseases. Ned. Tijdschr. Geneeskd. 150: 948-955 (2006).

• Jaudszus A, Krokowski M, Mockel P, Darcan Y, Avagyan A, Matricardi P, Jahreis G, Hamelmann E. cis-9,trans-11-Conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J. Nutr. 138: 1336-1342 (2008). *

• Javidan-Nejad C, Bhalla S. Bronchiectasis. Radiol. Clin. North Am. 47: 289-306 (2009).

• Javor J, Bucova M, Ferencik S, Grosse-Wilde H, Buc M. Single nucleotide polymorphisms of cytokine genes in the healthy Slovak population. Int. J. Immunogenet. 34: 273-280 (2007). *

• Jennings S, Prescott SL. Early dietary exposures and feeding practices: role in pathogenesis and prevention of allergic disease? Postgrad. Med. J. 86: 94-99 (2010).

• Jeon EJ, Lee SK, Park YS, Kim DH, Yum JH, Park CS. The effects of peroxisome proliferator-activated receptor-gamma agonist on a murine model of experimental allergic rhinitis. Otolaryngol. Head Neck Surg. 139: 124-130 (2008).

• Jeong HJ, Na HJ, Kim SJ, Rim HK, Myung NY, Moon PD, Han NR, Seo JU, Kang TH, Kim JJ, Choi Y, Kang IC, Hong SH, Kim YA, Seo YW, Kim HM, Um JY. Anti-inflammatory effect of columbianetin on activated human mast cells. Biol. Pharm. Bull. 32: 1027-1031 (2009). *

• Jiang S, Lechler RI. CD4(+)CD25(+) regulatory T-cell therapy for allergy, autoimmune disease and transplant rejection. Inflamm. Allergy Drug Targets 5: 239-242 (2006).

• Jiao ZM, Fu YH, Fu J, Zhang F, Wang WZ. 1,25-Dihydroxyvitamin D3 promotes the apoptosis of inflammatory cells in acute experimental autoimmune encephalomyelitis:experiment with rats. Zhonghua Yi Xue Za Zhi 88: 2350-2354 (2008).

• Jin H, Kumar L, Mathias C, Zurakowski D, Oettgen H, Gorelik L, Geha R. Toll-like receptor 2 is important for the T(H)1 response to cutaneous sensitization. J. Allergy Clin. Immunol. 123: 875-882.e1 (2009). *

• Jirholt J, Cook A, Emahazion T, Sundvall M, Jansson L, Nordquist N, Pettersson U, Holmdahl R. Genetic linkage analysis of collagen-induced arthritis in the mouse. Eur. J. Immunol. 28: 3321-3328 (1998). *

• Joachim RA, Noga O, Sagach V, Hanf G, Fliege H, Kocalevent RD, Peters EM, Klapp BF. Correlation between immune and neuronal parameters and stress perception in allergic asthmatics. Clin. Exp. Allergy 38: 283-290 (2007). *

• Joetham A, Takeda K, Okamoto M, Taube C, Matsuda H, Dakhama A, Gelfand EW. Antigen specificity is not required for modulation of lung allergic responses by naturally occurring regulatory T cells. J. Immunol. 183: 1821-1827 (2009).

• Johansen P, Senti G, Martinez Gomez JM, Storni T, von Beust BR, Wuthrich B, Bot A, Kundig TM. Toll-like receptor ligands as adjuvants in allergen-specific immunotherapy. Clin. Exp. Allergy 35: 1591-1598 (2005). *

• Johansson S, Lonnqvist A, Ostman S, Sandberg AS, Wold AE. Long-chain polyunsaturated fatty acids are consumed during allergic inflammation and affect T helper type 1 (Th1)- and Th2-mediated hypersensitivity differently. Clin. Exp. Immunol. Feb 10 [Epub ahead of print] (2010). *

• Johnson AJ, Suidan GL, McDole J, Pirko I. The CD8 T cell in multiple sclerosis: suppressor cell or mediator of neuropathology? Int. Rev. Neurobiol. 79C: 73-97 (2007).

• Johnson BA, Baban B, Mellor AL. Targeting the immunoregulatory indoleamine 2,3 dioxygenase pathway in immunotherapy. Immunotherapy 1: 645-661 (2009).

• Johnson HM, Torres BA, Soos JM. Superantigens: structure and relevance to human disease. Proc. Soc. Exp. Biol. Med. 212: 99-109 (1996).

• Johnson W Jr. Final report on the safety assessment of Capsicum annuum extract, Capsicum annuum fruit extract, Capsicum annuum resin, Capsicum annuum fruit powder, Capsicum frutescens fruit, Capsicum frutescens fruit extract, Capsicum frutescens resin, and capsaicin. Int. J. Toxicol. 26 Suppl. 1: 3-106 (2007). *

• Johnson Z, Schwarz M, Power CA, Wells TN, Proudfoot AE. Multi-faceted strategies to combat disease by interference with the chemokine system. Trends Immunol. 26: 268-274 (2005). *

• Jones G. Susceptibility to asthma and eczema from mucosal and epidermal expression of distinctive genes. Curr. Allergy Asthma Rep. 7: 11-17 (2007).

• Jovanovic M, Boza P, Karadaglic D, Brkic S, Petrovic A, Mimica-Dukic N, Anackov G, Poljacki M. Contact sensitivity in patients with psoriasis in Vojvodina. Int. Arch. Allergy Immunol. 148: 311-320 (2008).

• Jung JS, Park BL, Cheong HS, Bae JS, Kim JH, Chang HS, Rhym T, Park JS, Jang AS, Lee YM, Kim KU, Uh ST, Na JO, Kim YH, Park CS, Shin HD. Association of IL17RB gene polymorphism with asthma. Chest 135: 1173-1180 (2009). *

• Juntunen R, Liukko A, Taivainen A, Narvanen A, Durand G, Kauppinen A, Nieminen A, Rytkonen-Nissinen M, Saarelainen S, Maillere B, Virtanen T, Kinnunen T. Suboptimal recognition of a T cell epitope of the major dog allergen Can f 1 by human T cells. Mol. Immunol. 46: 3320-3327 (2009). *

• Jurakic Toncic R, Lipozencic J, Marinovic B. Treatment of chronic urticaria. Acta Dermatovenerol. Croat. 17: 305-322 (2009).

• Jyonouchi H, Geng L, Cushing-Ruby A, Quraishi H. Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study. J. Neuroinflammation 5: 52 (2008).

• Kabashima K, Tokura Y. The potential of selected prostanoid receptors as targets in a new therapeutic strategy for allergy and immune diseases. Curr. Drug Saf. 2: 186-192 (2007).

• Kabesch M, Peters W, Carr D, Leupold W, Weiland SK, von Mutius E. Association between polymorphisms in caspase recruitment domain containing protein 15 and allergy in two German populations. J. Allergy Clin. Immunol. 111: 813-817 (2003). *

• Kagami S, Kanari H, Suto A, Fujiwara M, Ikeda K, Hirose K, Watanabe N, Iwamoto I, Nakajima H. HMG-CoA reductase inhibitor simvastatin inhibits proinflammatory cytokine production from murine mast cells. Int. Arch. Allergy Immunol. 146 Suppl. 1: 61-66 (2008).

• Kaiser HB. Risk factors in allergy/asthma. Allergy Asthma Proc. 25: 7-10 (2004).

• Kallinich T, Schmidt S, Hamelmann E, Fischer A, Qin S, Luttmann W, Virchow JC, Kroczek RA. Chemokine-receptor expression on T cells in lung compartments of challenged asthmatic patients. Clin. Exp. Allergy 35: 26-33 (2005).

• Kalliomaki M, Isolauri E. Pandemic of atopic diseases - a lack of microbial exposure in early infancy? Curr. Drug Targets Infect. Disord. 2: 193-199 (2002).

• Kalliomaki M, Isolauri E. Role of intestinal flora in the development of allergy. Curr. Opin. Allergy Clin. Immunol. 3: 15-20 (2003).

• Kalpaklioglu AF, Turan M. Possible association between cockroach allergy and HLA class II antigens. Ann. Allergy Asthma Immunol. 89: 155-158 (2002).

• Kamal SM, El Sayed Khalifa K. Immune modulation by helminthic infections: worms and viral infections. Parasite Immunol. 28: 483-496 (2006). *

• Kamanli A, Ardicoglu O, Godekmerdan A. HLA-B27 subtypes in patients with spondylarthropathies, IgE levels against some allergens and their relationship to the disease parameters. Bratisl. Lek. Listy. 110: 480-485 (2009).

• Kambayashi T, Allenspach EJ, Chang JT, Zou T, Shoag JE, Reiner SL, Caton AJ, Koretzky GA. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. J. Immunol. 182: 4686-4695 (2009).

• Kambayashi T, Larosa DF, Silverman MA, Koretzky GA. Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation. Immunol. Rev. 232: 99-114 (2009). *

• Kamimura Y, Kobori H, Piao J, Hashiguchi M, Matsumoto K, Hirose S, Azuma M. Possible involvement of soluble B7-H4 in T cell-mediated inflammatory immune responses. Biochem. Biophys. Res. Commun. 389: 349-353 (2009). *

• Kamisawa T, Anjiki H, Egawa N, Kubota N. Allergic manifestations in autoimmune pancreatitis. Eur. J. Gastroenterol. Hepatol. 21: 1136-1139 (2009).

• Kamiya T, Shikano M, Wada T, Sasaki M, Joh T. The efficacy of probiotics in gastrointestinal disease. Nippon Rinsho 66: 1385-1390 (2008).

• Kamm MA. Chronic active disease and maintaining remission in Crohn's disease. Aliment. Pharmacol. Ther. 20 Suppl. 4: 102-105 (2004). *

• Kamradt T, Goggel R, Erb KJ. Induction, exacerbation and inhibition of allergic and autoimmune diseases by infection. Trends Immunol. 26: 260-267 (2005). *

• Kamradt T, Volkmer-Engert R. Cross-reactivity of T lymphocytes in infection and autoimmunity. Mol. Divers. 8: 271-280 (2004).

• Kamsteeg M, Jansen PA, van Vlijmen-Willems IM, van Erp PE, Rodijk-Olthuis D, van der Valk PG, Feuth T, Zeeuwen PL, Schalkwijk J. Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis. Br. J. Dermatol. Oct 10 [Epub ahead of print] (2009). *

• Kanada S, Nakano N, Potaczek DP, Maeda K, Shimokawa N, Niwa Y, Fukai T, Sanak M, Szczeklik A, Yagita H, Okumura K, Ogawa H, Nishiyama C. Two different transcription factors discriminate the -315C>T polymorphism of the FcepsilonRIalpha gene: binding of Sp1 to -315C and of a high mobility group-related molecule to -315T. J. Immunol. 180: 8204-8210 (2008). *

• Kanazawa N, Furukawa F. Autoinflammatory syndromes with a dermatological perspective. J. Dermatol. 34: 601-618 (2007).

• Kanda N, Koike S, Watanabe S. IL-17 suppresses TNF-alpha-induced CCL27 production through induction of COX-2 in human keratinocytes. J. Allergy Clin. Immunol. 116: 1144-1150 (2005). *

• Kanda N, Shimizu T, Tada Y, Watanabe S. IL-18 enhances IFN-gamma-induced production of CXCL9, CXCL10, and CXCL11 in human keratinocytes. Eur. J. Immunol. 37: 338-350 (2007). *

• Kang HJ, Choi YM, Chae SW, Woo JS, Hwang SJ, Lee HM. Polymorphism of the CD14 gene in perennial allergic rhinitis. Int. J. Pediatr. Otorhinolaryngol. 70: 2081-2085 (2006).

• Kang HJ, Cinn YG, Hwang SJ, Won Chae S, Woo JS, Lee SH, Lee HM. Up-regulation of peroxisome proliferator-activated receptor gamma in perennial allergic rhinitis. Arch. Otolaryngol. Head Neck Surg. 132: 1196-1200 (2006).

• Kang I, An XH, Oh YK, Lee SH, Jung HM, Chae SC, Lee JH. Identification of polymorphisms in the RNase3 gene and the association with allergic rhinitis. Eur. Arch. Otorhinolaryngol. Sep 17 [Epub ahead of print] (2009).

• Kanu A, Patel K. Treatment of allergic bronchopulmonary aspergillosis (ABPA) in CF with anti-IgE antibody (omalizumab). Pediatr. Pulmonol. 43: 1249-1251 (2008).

• Kanzato H, Fujiwara S, Ise W, Kaminogawa S, Sato R, Hachimura S. Lactobacillus acidophilus strain L-92 induces apoptosis of antigen-stimulated T cells by modulating dendritic cell function. Immunobiology 213: 399-408 (2008).

• Kaplan AP, Joseph K, Maykut RJ, Geba GP, Zeldin RK. Treatment of chronic autoimmune urticaria with omalizumab. J. Allergy Clin. Immunol. 122: 569-573 (2008). *

• Karra L, Berent-Maoz B, Ben-Zimra M, Levi-Schaffer F. Are we ready to downregulate mast cells? Curr. Opin. Immunol. 21: 708-714 (2009).

• Karsh J, Chen Y, Lin M, Dales R. The association between allergy and rheumatoid arthritis in the Canadian population. Eur. J. Epidemiol. 20: 783-787 (2005). *

• Karwot R, Maxeiner JH, Schmitt S, Scholtes P, Hausding M, Lehr HA, Glimcher LH, Finotto S. Protective role of nuclear factor of activated T cells 2 in CD8+ long-lived memory T cells in an allergy model. J. Allergy Clin. Immunol. 121: 992-999.e6 (2008). *

• Kasakura K, Takahashi K, Aizawa T, Hosono A, Kaminogawa S. A TLR2 ligand suppresses allergic inflammatory reactions by acting directly on mast cells. Int. Arch. Allergy Immunol. 150: 359-369 (2009).

• Kasashima S, Zen Y, Kawashima A, Endo M, Matsumoto Y, Kasashima F. A new clinicopathological entity of IgG4-related inflammatory abdominal aortic aneurysm. J. Vasc. Surg. 49: 1264-1271 (2009).

• Kashiwakura JI, Xiao W, Kitaura J, Kawakami Y, Maeda-Yamamoto M, Pfeiffer JR, Wilson BS, Blank U, Kawakami T. Pivotal advance: IgE accelerates in vitro development of mast cells and modifies their phenotype. J. Leukoc. Biol. 84: 357-367 (2008). *

• Kato A, Chustz RT, Ogasawara T, Kulka M, Saito H, Schleimer RP, Matsumoto K. Dexamethasone and FK506 inhibit expression of distinct subsets of chemokines in human mast cells. J. Immunol. 182: 7233-7243 (2009).

• Kato A, Xiao H, Chustz RT, Liu MC, Schleimer RP. Local release of B cell-activating factor of the TNF family after segmental allergen challenge of allergic subjects. J. Allergy Clin. Immunol. 123: 369-375 (2009). *

• Kato T, Kiire A, Yamagata H, Yamanaka H, Kamatani N. Hypersensitivity reaction against influenza vaccine in a patient with rheumatoid arthritis after the initiation of etanercept injections. Mod. Rheumatol. 16: 327-329 (2006). *

• Katsanos GS, Anogeianaki A, Orso C, Tete S, Salini V, Antinolfi PL, Sabatino G. Mast cells and chemokines. J. Biol. Regul. Homeost. Agents 22: 145-152 (2008).

• Katsara M, Minigo G, Plebanski M, Apostolopoulos V. The good, the bad and the ugly: how altered peptide ligands modulate immunity. Expert Opin. Biol. Ther. 8: 1873-1884 (2008).

• Katz DP, Manner T, Furst P, Askanazi J. The use of an intravenous fish oil emulsion enriched with omega-3 fatty acids in patients with cystic fibrosis. Nutrition 12: 334-339 (1996).

• Katz Y, Goldberg MR, Zadik-Mnuhin G, Leshno M, Heyman E. Cross-sensitization between milk proteins: reactivity to a "kosher" epitope? Isr. Med. Assoc. J. 10: 85-88 (2008). *

• Kaur S, Gupta VK, Shah A, Thiel S, Sarma PU, Madan T. Elevated levels of mannan-binding leptin (MBL) and eosinophilia in patients of bronchial asthma with allergic rhinitis and allergic bronchopulmonary aspergillosis associate with a novel intronic polymorphism in MBL. Clin. Exp. Immunol. 143: 414-419 (2006). *

• Kawada M, Hachiya Y, Arihiro A, Mizoguchi E. Role of mammalian chitinases in inflammatory conditions. Keio. J. Med. 56: 21-27 (2007). *

• Kawaguchi M, Kokubu F, Fujita J, Huang SK, Hizawa N. Role of interleukin-17F in asthma. Inflamm. Allergy Drug Targets 8: 383-389 (2009).

• Kawakami T, Galli SJ. Regulation of mast-cell and basophil function and survival by IgE. Nat. Rev. Immunol. 2: 773-786 (2002).

• Kaya S, Demirci M, Sesli Cetin E, Cicioglu Aridogan B, Sahin M, Tas T, Korkmaz M. Investigation of the presence of autoantibodies in patients with toxocariasis. Mikrobiyol. Bul. 43: 661-666 (2009).

• Kebir H, Ifergan I, Alvarez JI, Bernard M, Poirier J, Arbour N, Duquette P, Prat A. Preferential recruitment of interferon-gamma-expressing T(H)17 cells in multiple sclerosis. Ann. Neurol. 66: 390-402 (2009).

• Keita AV, Stertman L, Sun YQ, Larhed A, Sjoholm I, Soderholm JD. Effects of chronic stress on the immune response to oral human serum albumin-conjugated starch microparticles in rats. J. Neuroimmunol. 183: 33-42 (2007).

• Kelly EA, Koziol-White CJ, Clay KJ, Liu LY, Bates ME, Bertics PJ, Jarjour NN. Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma. J. Immunol. 182: 1404-1410 (2009).

• Kelly-Welch AE, Hanson EM, Boothby MR, Keegan AD. Interleukin-4 and interleukin-13 signaling connections maps. Science 300: 1527-1528 (2003). *

• Kempuraj D, Tagen M, Iliopoulou BP, Clemons A, Vasiadi M, Boucher W, House M, Wolfberg A, Theoharides TC. Luteolin inhibits myelin basic protein-induced human mast cell activation and mast cell-dependent stimulation of Jurkat T cells. Br. J. Pharmacol. 155: 1076-1084 (2008). *

• Kennedy MJ, Loehle JA, Griffin AR, Doll MA, Kearns GL, Sullivan JE, Hein DW. Association of the histamine N-methyltransferase C314T (Thr105Ile) polymorphism with atopic dermatitis in Caucasian children. Pharmacotherapy 28: 1495-1501 (2008).

• Kephart GM, Alexander JA, Arora AS, Romero Y, Smyrk TC, Talley NJ, Kita H. Marked deposition of eosinophil-derived neurotoxin in adult patients with eosinophilic esophagitis. Am. J. Gastroenterol. Nov 3 [Epub ahead of print] (2009). *

• Kere J. Mapping genes for asthma and psoriasis. Novartis Found. Symp. 267: 46-52 (2005).

• Kess D, Lindqvist AK, Peters T, Wang H, Zamek J, Nischt R, Broman KW, Blakytny R, Krieg T, Holmdahl R, Scharffetter-Kochanek K. Identification of susceptibility loci for skin disease in a murine psoriasis model. J. Immunol. 177: 4612-4619 (2006). *

• Kevans D, Keegan D, Mulcahy HE, O'Donoghue DP. Infliximab therapy in Crohn's disease: a pragmatic approach? Aliment. Pharmacol. Ther. 24: 351-359 (2006). *

• Khan S, Orenstein SR. Eosinophilic gastroenteritis: epidemiology, diagnosis and management. Paediatr. Drugs 4: 563-570 (2002).

• Kiesler P, Haynes PA, Shi L, Kao PN, Wysocki VH, Vercelli D. NF45 and NF90 regulate HS4-dependent interleukin-13 transcription in T cells. J. Biol. Chem. Jan 5 [Epub ahead of print] (2010). *

• Kiesler P, Shakya A, Tantin D, Vercelli D. An allergy-associated polymorphism in a novel regulatory element enhances IL13 expression. Hum. Mol. Genet. 18: 4513-4520 (2009).

• Kim E, Kang BY, Kim TS. Inhibition of interleukin-12 production in mouse macrophages by hydroquinone, a reactive metabolite of benzene, via suppression of nuclear factor-kappaB binding activity. Immunol. Lett. 99: 24-29 (2005).

• Kim E, Lee JE, Namkung JH, Kim PS, Kim S, Shin ES, Cho EY, Yang JM. Single nucleotide polymorphisms and the haplotype in the DEFB1 gene are associated with atopic dermatitis in a Korean population. J. Dermatol. Sci. 54: 25-30 (2009).

• Kim E, Lee JE, Namkung JH, Park JH, Kim S, Shin ES, Cho EY, Yang JM. Association of the single-nucleotide polymorphism and haplotype of the interleukin 18 gene with atopic dermatitis in Koreans. Clin. Exp. Allergy 37: 865-871 (2007). *

• Kim JJ, Min JY, Lee JH. Polymorphisms in the IL-13 and IL-4 receptor alpha genes and allergic rhinitis. Eur. Arch. Otorhinolaryngol. 264: 395-399 (2007). *

• Kim KR, Cho SH, Choi SJ, Jeong JH, Lee SH, Park CW, Tae K. TAP1 and TAP2 gene polymorphisms in Korean patients with allergic rhinitis. J. Korean Med. Sci. 22: 825-831 (2007). *

• Kim NI, Jo YJ, Song MH, Kim SH, Kim TH, Park YS, Eom WY, Kim SW. Clinical features of eosinophilic gastroenteritis. Korean J. Gastroenterol. 44: 217-223 (2004).

• Kim SH, Choi JH, Lee KW, Kim SH, Shin ES, Oh HB, Suh CH, Nahm DH, Park HS. The human leucocyte antigen-DRB1*1302-DQB1*0609-DPB1*0201 haplotype may be a strong genetic marker for aspirin-induced urticaria. Clin. Exp. Allergy 35: 339-344 (2005). *

• Kim SH, Lee JE, Kim SH, Jee YK, Kim YK, Park HS, Min KU, Park HW; The Adverse Drug Reaction Research Group in Korea. Allelic variants of CD40 and CD40L genes interact to promote antibiotic-induced cutaneous allergic reactions. Clin. Exp. Allergy Sep 3 [Epub ahead of print] (2009). *

• Kim Y, Park CS, Shin HD, Choi JW, Cheong HS, Park BL, Choi YH, Jang AS, Park SW, Lee YM, Lee EJ, Park SG, Lee JY, Lee JK, Han BG, Oh B, Kimm K. A promoter nucleotide variant of the dendritic cell-specific DCNP1 associates with serum IgE levels specific for dust mite allergens among the Korean asthmatics. Genes Immun. 8: 369-378 (2007). *

• Kim-Saijo M, Janssen EM, Sugie K. CD4 cell-secreted, posttranslationally modified cytokine GIF suppresses Th2 responses by inhibiting the initiation of IL-4 production. Proc. Natl. Acad. Sci. U.S.A. 105: 19402-19407 (2008). *

• Kimura Y, Takada T, Kawarada Y, Nimura Y, Hirata K, Sekimoto M, Yoshida M, Mayumi T, Wada K, Miura F, Yasuda H, Yamashita Y, Nagino M, Hirota M, Tanaka A, Tsuyuguchi T, Strasberg SM, Gadacz TR. Definitions, pathophysiology, and epidemiology of acute cholangitis and cholecystitis: Tokyo Guidelines. J. Hepatobiliary Pancreat. Surg. 14: 15-26 (2007). *

• Kindermann A, Lopes AI. Helicobacter pylori infection in pediatrics. Helicobacter 14 Suppl. 1: 52-57 (2009). *

• King MJ, Hanania NA. Asthma in the elderly: current knowledge and future directions. Curr. Opin. Pulm. Med. 16: 55-59 (2010).

• Kinjyo I, Inoue H, Hamano S, Fukuyama S, Yoshimura T, Koga K, Takaki H, Himeno K, Takaesu G, Kobayashi T, Yoshimura A. Loss of SOCS3 in T helper cells resulted in reduced immune responses and hyperproduction of interleukin 10 and transforming growth factor-beta 1. J. Exp. Med. 203: 1021-1031 (2006). *

• Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA. J. Allergy Clin. Immunol. 123: 179-186 (2009). *

• Kiss A, Montes M, Susarla S, Jaensson EA, Drouin SM, Wetsel RA, Yao Z, Martin R, Hamzeh N, Adelagun R, Amar S, Kheradmand F, Corry DB. A new mechanism regulating the initiation of allergic airway inflammation. J. Allergy Clin. Immunol. 120: 334-342 (2007). *

• Kitagaki K, Businga TR, Racila D, Elliott DE, Weinstock JV, Kline JN. Intestinal helminths protect in a murine model of asthma. J. Immunol. 177: 1628-1635 (2006). *

• Kitajima M, Iwamura C, Miki-Hosokawa T, Shinoda K, Endo Y, Watanabe Y, Shinnakasu R, Hosokawa H, Hashimoto K, Motohashi S, Koseki H, Ohara O, Yamashita M, Nakayama T. Enhanced Th2 cell differentiation and allergen-induced airway inflammation in Zfp35-deficient mice. J. Immunol. 183: 5388-5396 (2009).

• Kiyono H, Kweon MN, Hiroi T, Takahashi I. The mucosal immune system: from specialized immune defense to inflammation and allergy. Acta Odontol. Scand. 59: 145-153 (2001).

• Klemens C, Rasp G, Jund F, Hilgert E, Devens C, Pfrogner E, Kramer MF. Mediators and cytokines in allergic and viral-triggered rhinitis. Allergy Asthma Proc. 28: 434-441 (2007).

• Kliegman RM, Clapp DW. Rational principles for immunoglobulin prophylaxis and therapy of neonatal infections. Clin. Perinatol. 18: 303-324 (1991).

• Kline JN, Krieg AM. Toll-like receptor 9 activation with CpG oligodeoxynucleotides for asthma therapy. Drug News Perspect. 21: 434-439 (2008).

• Knapp B, Omasits U, Bohle B, Maillere B, Ebner C, Schreiner W, Jahn-Schmid B. 3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model. Mol. Immunol. 46: 1839-1844 (2009). *

• Kneilling M, Rocken M. Mast cells: novel clinical perspectives from recent insights. Exp. Dermatol. 18: 488-496 (2009).

• Knight AK, Blazquez AB, Zhang S, Mayer L, Sampson HA, Berin MC. CD4 T cells activated in the mesenteric lymph node mediate gastrointestinal food allergy in mice. Am. J. Physiol. Gastrointest. Liver Physiol. 293: G1234-G1243 (2007). *

• Knisz J, Banks A, McKeag L, Metcalfe DD, Rothman PB, Brown JM. Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation. Clin. Immunol. 132: 277-284 (2009). *

• Knudsen TT, Thorsen S, Jensen SA, Dalhoff K, Schmidt LE, Becker U, Bendtsen F. Effect of intravenous N-acetylcysteine infusion on haemostatic parameters in healthy subjects. Gut 54: 515-521 (2005). *

• Ko J, Yun CY, Lee JS, Kim DH, Yuk JE, Kim IS. Differential regulation of CC chemokine receptors by 9-cis retinoic acid in the human mast cell line, HMC-1. Life Sci. 79: 1293-1300 (2006). *

• Ko KW, Corry DB, Brayton CF, Paul A, Chan L. Extravascular inflammation does not increase atherosclerosis in ApoE-deficient mice. Biochem. Biophys. Res. Commun. 384: 93-99 (2009). *

• Koch A, Knobloch J, Dammhayn C, Raidl M, Ruppert A, Hag H, Rottlaender D, Muller K, Erdmann E. Effect of bacterial endotoxin LPS on expression of INF-gamma and IL-5 in T-lymphocytes from asthmatics. Clin. Immunol. 125: 194-204 (2007). *

• Koch M, De Keyser J. Uric acid in multiple sclerosis. Neurol. Res. 28: 316-319 (2006).

• Koehm S, Slavin RG, Hutcheson PS, Trejo T, David CS, Bellone CJ. HLA-DRB1 alleles control allergic bronchopulmonary aspergillosis-like pulmonary responses in humanized transgenic mice. J. Allergy Clin. Immunol. 120: 570-577 (2007).

• Kojima K, Nagayama R, Hirama S, Maeda T, Takikawa H, Miyake K, Yamanaka M, Shiga J. Epstein-Barr virus infection resembling autoimmune hepatitis with lactate dehydrogenase and alkaline phosphatase anomaly. J. Gastroenterol. 34: 706-712 (1999).

• Koletzko B, Demmelmair H, Schaeffer L, Illig T, Heinrich J. Genetically determined variation in polyunsaturated fatty acid metabolism may result in different dietary requirements. Nestle Nutr. Workshop Ser. Pediatr. Program 62: 35-49 (2008).

• Kolho KL, Ruuska T, Savilahti E. Severe adverse reactions to infliximab therapy are common in young children with inflammatory bowel disease. Acta Paediatr. 96: 128-130 (2007). *

• Komiya A, Nagase H, Okugawa S, Ota Y, Suzukawa M, Kawakami A, Sekiya T, Matsushima K, Ohta K, Hirai K, Yamamoto K, Yamaguchi M. Expression and function of Toll-like receptors in human basophils. Int. Arch. Allergy Immunol. 140 Suppl. 1: 23-27 (2006).

• Kondo S, Isayama H, Akahane M, Toda N, Sasahira N, Nakai Y, Yamamoto N, Hirano K, Komatsu Y, Tada M, Yoshida H, Kawabe T, Ohtomo K, Omata M. Detection of common bile duct stones: comparison between endoscopic ultrasonography, magnetic resonance cholangiography, and helical-computed-tomographic cholangiography. Eur. J. Radiol. 54: 271-275 (2005).

• Kondo S, McKenzie RC, Sauder DN. Interleukin-10 inhibits the elicitation phase of allergic contact hypersensitivity. J. Invest. Dermatol. 103: 811-814 (1994). *

• Kong JS, Teuber SS, Gershwin ME. Potential adverse events with biologic response modifiers. Autoimmun. Rev. 5: 471-485 (2006).

• Koppen S, de Groot R, Neijens HJ, Nagelkerke N, van Eden W, Rumke HC. No epidemiological evidence for infant vaccinations to cause allergic disease. Vaccine 22: 3375-3385 (2004). *

• Korelitz BI, Zlatanic J, Goel F, Fuller S. Allergic reactions to 6-mercaptopurine during treatment of inflammatory bowel disease. J. Clin. Gastroenterol. 28: 341-344 (1999).

• Koretz RL, Avenell A, Lipman TO, Braunschweig CL, Milne AC. Does enteral nutrition affect clinical outcome? A systematic review of the randomized trials. Am. J. Gastroenterol. 102: 412-429 (2007). *

• Kormelink TG, Abudukelimu A, Redegeld FA. Mast cells as target in cancer therapy. Curr. Pharm. Des. 15: 1868-1878 (2009).

• Korzenik JR. Past and current theories of etiology of IBD: toothpaste, worms, and refrigerators. J. Clin. Gastroenterol. 39: S59-S65 (2005).

• Koutroubakis IE, Oustamanolakis P, Karakoidas C, Mantzaris GJ, Kouroumalis EA. Safety and efficacy of total-dose infusion of low molecular weight iron dextran for iron deficiency anemia in patients with inflammatory bowel disease. Dig. Dis. Sci. Oct 16 [Epub ahead of print] (2009). *

• Koyama K, Ozawa T, Hatsushika K, Ando T, Takano S, Wako M, Suenaga F, Ohnuma Y, Ohba T, Katoh R, Sugiyama H, Hamada Y, Ogawa H, Okumura K, Nakao A. A possible role for TSLP in inflammatory arthritis. Biochem. Biophys. Res. Commun. 357: 99-104 (2007). *

• Koyanagi M, Baguet A, Martens J, Margueron R, Jenuwein T, Bix M. EZH2 and H3-trimethyl lysine 27 associated with Il4 and Il13 gene silencing in TH1 cells. J. Biol. Chem. 280: 31470-31477 (2005). *

• Kraemer R, Delosea N, Ballinari P, Gallati S, Crameri R. Effect of allergic broncho-pulmonary aspergillosis on lung function in children with cystic fibrosis. Am. J. Respir. Crit. Care Med. 174: 1211-1220 (2006). *

• Kraft S, Kinet JP. New developments in FcepsilonRI regulation, function and inhibition. Nat. Rev. Immunol. 7: 365-378 (2007). *

• Kraft S, Novak N. Fc receptors as determinants of allergic reactions. Trends Immunol. 27: 88-95 (2006). *

• Kramer DR, Sutherland RM, Bao S, Husband AJ. Cytokine mediated effects in mucosal immunity. Immunol. Cell Biol. 73: 389-396 (1995). *

• Krauss-Etschmann S, Hartl D, Rzehak P, Heinrich J, Shadid R, Ramírez-Tortosa MD, Campoy C, Pardillo S, Schendel DJ, Decsi T, Demmelmair H, Koletzko BV; Nutraceuticals for Healthier Life Study Group. Decreased cord blood IL-4, IL-13, and CCR4 and increased TGF-beta levels after fish oil supplementation of pregnant women. J. Allergy Clin. Immunol. 121: 464-470.e6 (2008). *

• Krecisz B, Chomiczewska D, Kiec-Swierczynska M. The role of regulatory T cells in allergic contact dermatitis. Med. Pr. 60: 315-319 (2009).

• Kremmyda LS, Vlachava M, Noakes PS, Diaper ND, Miles EA, Calder PC. Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fatty acids: a systematic review. Clin. Rev. Allergy Immunol. Dec 9 [Epub ahead of print] (2009). *

• Kriegel MA, Rathinam C, Flavell RA. E3 ubiquitin ligase GRAIL controls primary T cell activation and oral tolerance. Proc. Natl. Acad. Sci. U.S.A. 106: 16770-16775 (2009). *

• Kristan SS, Malovrh MM, Silar M, Kern I, Flezar M, Kosnik M, Suskovic S, Korosec P. Airway angiogenesis in patients with rhinitis and controlled asthma. Clin. Exp. Allergy 39: 354-360 (2009).

• Kristinsson SY, Koshiol J, Bjorkholm M, Goldin LR, McMaster ML, Turesson I, Landgren O. Immune-related and inflammatory conditions and risk of lymphoplasmacytic lymphoma or Waldenstrom macroglobulinemia. J. Natl. Cancer Inst. Feb 24 [Epub ahead of print] (2010). *

• Kruschinski C, Skripuletz T, Bedoui S, Raber K, Straub RH, Hoffmann T, Grote K, Jacobs R, Stephan M, Pabst R, von Horsten S. Postnatal life events affect the severity of asthmatic airway inflammation in the adult rat. J. Immunol. 180: 3919-3925 (2008). *

• Kruzel ML, Bacsi A, Choudhury B, Sur S, Boldogh I. Lactoferrin decreases pollen antigen-induced allergic airway inflammation in a murine model of asthma. Immunology 119: 159-166 (2006). *

• Kuchroo VK, Umetsu DT, DeKruyff RH, Freeman GJ. The TIM gene family: emerging roles in immunity and disease. Nat. Rev. Immunol. 3: 454-462 (2003). *

• Kuehn HS, Gilfillan AM. G protein-coupled receptors and the modification of FcepsilonRI-mediated mast cell activation. Immunol. Lett. 113: 59-69 (2007).

• Kuehn HS, Swindle EJ, Kim MS, Beaven MA, Metcalfe DD, Gilfillan AM. The phosphoinositide 3-kinase-dependent activation of Btk is required for optimal eicosanoid production and generation of reactive oxygen species in antigen-stimulated mast cells. J. Immunol. 181: 7706-7712 (2008). *

• Kuga K, Nishifuji K, Iwasaki T. Cyclosporine A inhibits transcription of cytokine genes and decreases the frequencies of IL-2 producing cells in feline mononuclear cells. J. Vet. Med. Sci. 70: 1011-1016 (2008). *

• Kukkonen K, Kuitunen M, Haahtela T, Korpela R, Poussa T, Savilahti E. High intestinal IgA associates with reduced risk of IgE-associated allergic diseases. Pediatr. Allergy Immunol. Jun 26 [Epub ahead of print] (2009).

• Kumar A, Gupta V, Changotra H, Sarin BC, Sehajpal PK. Tumor necrosis factor - alpha and transforming growth factor - beta1 polymorphisms in bronchial asthma. Indian J. Med. Sci. 62: 323-330 (2008). *

• Kumar A, Teuber SS, Gershwin ME. Why do people die of anaphylaxis? - a clinical review. Clin. Dev. Immunol. 12: 281-287 (2005). *

• Kumar A, Teuber SS, Gershwin ME. Current perspectives on primary immunodeficiency diseases. Clin. Dev. Immunol. 13: 223-259 (2006). *

• Kumari J, Larsen AN, Bogwald J, Dalmo RA. Interleukin-17D in Atlantic salmon (Salmo salar): molecular characterization, 3D modelling and promoter analysis. Fish Shellfish Immunol. 27: 647-659 (2009).

• Kung SJ, Choudhary C, McGeady SJ, Cohn JR. Lack of cross-reactivity between 5-aminosalicylic acid-based drugs: a case report and review of the literature. Ann. Allergy Asthma Immunol. 97: 284-287 (2006).

• Kuokkanen S, Sundvall M, Terwilliger JD, Tienari PJ, Wikstrom J, Holmdahl R, Pettersson U, Peltonen L. A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2. Nat. Genet. 13: 477-480 (1996). *

• Kurokawa M, Konno S, Matsukura S, Kawaguchi M, Ieki K, Suzuki S, Odaka M, Watanabe S, Homma T, Sato M, Takeuchi H, Hirose T, Huang SK, Adachi M. Effects of corticosteroids on osteopontin expression in a murine model of allergic asthma. Int. Arch. Allergy Immunol. 149 Suppl. 1: 7-13 (2009).

• Kurokawa M, Konno S, Takahashi A, Plunkett B, Rittling SR, Matsui Y, Kon S, Morimoto J, Uede T, Matsukura S, Kokubu F, Adachi M, Nishimura M, Huang SK. Regulatory role of DC-derived osteopontin in systemic allergen sensitization. Eur. J. Immunol. 39: 3323-3330 (2009). *

• Kurz T, Strauch K, Dietrich H, Braun S, Hierl S, Jerkic SP, Wienker TF, Deichmann KA, Heinzmann A. Multilocus haplotype analyses reveal association between 5 novel IL-15 polymorphisms and asthma. J. Allergy Clin. Immunol. 113: 896-901 (2004). *

• Kuwana M. Induction of anergic and regulatory T cells by plasmacytoid dendritic cells and other dendritic cell subsets. Hum. Immunol. 63: 1156-1163 (2002).

• Kwiatkowska-Patzer B, Michalkiewicz J, Kubiszewska I, Zielinska J, Kasarello K, Kurzepa K, Lipkowski AW. Spinal cord hydrolysate ameliorate immunological reaction in experimental allergic encephalomyelitis. Acta Neurobiol. Exp. (Wars.) 69: 73-78 (2009).

• Kyttaris VC, Tsokos GC. Syk kinase as a treatment target for therapy in autoimmune diseases. Clin. Immunol. 124: 235-237 (2007). *

• Lachheb J, Chelbi H, Hamzaoui K, Hamzaoui A. Association between RANTES polymorphisms and asthma severity among Tunisian children. Hum. Immunol. 68: 675-680 (2007).

• LaDuca JR, Gaspari AA. Targeting tumor necrosis factor alpha. New drugs used to modulate inflammatory diseases. Dermatol. Clin. 19: 617-635 (2001).

• Lagranderie M, Abolhassani M, Vanoirbeek JA, Lima C, Balazuc AM, Vargaftig BB, Marchal G. Mycobacterium bovis Bacillus Calmette-Guerin killed by extended freeze-drying targeted plasmacytoid dendritic cells to regulate lung inflammation. J. Immunol. 184: 1062-1070 (2010).

• Lake AM. Allergic bowel disease. Adolesc. Med. Clin. 15: 105-117, ix-x (2004).

• Lalive PH, Menge T, Delarasse C, Gaspera BD, Pham-Dinh D, Villoslada P, von Budingen HC, Genain CP. Antibodies to native myelin oligodendrocyte glycoprotein are serologic markers of early inflammation in multiple sclerosis Proc. Natl. Acad. Sci. U.S.A. 103: 2280-2285 (2006). *

• Lambrecht BN, Hammad H. Biology of lung dendritic cells at the origin of asthma. Immunity 31: 412-424 (2009). *

• Lamoureux G, Boulay G, Borduas AG. A cytotoxic antibody for cultured nervous tissue in serum and cerebrospinal fluid from rhesus monkeys with allergic encephalomyelitis. Clin. Exp. Immunol. 1: 307-321 (1966). *

• Lamoureux G, Carnegie PR, McPherson TA, Johnston D. Experimental allergic encephalomyelitis: immunological properties of encephalitogenic polypeptides and proteins. Clin. Exp. Immunol. 2: 601-609 (1967). *

• Lamoureux G, McPherson TA, Carnegie PR. Attempts to transfer experimental allergic encephalomyelitis in guinea-pigs by lymph node fragments in millipore chambers. Clin. Exp. Immunol. 2: 253-255 (1967). *

• Landgren E, Braback L, Hedlin G, Hjern A, Rasmussen F. Psoriasis in Swedish conscripts: time trend and association with T-helper 2-mediated disorders. Br. J. Dermatol. 154: 332-336 (2006). *

• Larche M. Peptide immunotherapy for allergic diseases. Allergy 62: 325-331 (2007). *

• Larche M. Regulatory T cells in allergy and asthma. Chest 132: 1007-1014 (2007). *

• Larche M. Update on the current status of peptide immunotherapy. J. Allergy Clin. Immunol. 119: 906-909 (2007). *

• Larche M, Wraith DC. Peptide-based therapeutic vaccines for allergic and autoimmune diseases. Nat. Med. 10 Suppl. 1: S69-S76 (2005). *

• Larrey D, Erlinger S. Drug-induced cholestasis. Baillieres Clin. Gastroenterol. 2: 423-452 (1988).

• Larsen JM, Bonefeld CM, Poulsen SS, Geisler C, Skov L. IL-23 and T(H)17-mediated inflammation in human allergic contact dermatitis. J. Allergy Clin. Immunol. 123: 486-492 (2009). *

• Larson RP, Zimmerli SC, Comeau MR, Itano A, Omori M, Iseki M, Hauser C, Ziegler SF. Dibutyl phthalate-induced thymic stromal lymphopoietin is required for Th2 contact hypersensitivity responses. J. Immunol. Feb 19 [Epub ahead of print] (2010).

• Lasisi AO, Abdullahi M. The inner ear in patients with nasal allergy. J. Natl. Med. Assoc. 100: 903-905 (2008).

• Latzin P, Hartl D, Regamey N, Frey U, Schoeni MH, Casaulta C. Comparison of serum markers for allergic bronchopulmonary aspergillosis in cystic fibrosis. Eur. Respir. J. 31: 36-42 (2008).

• Lawrence BP, Denison MS, Novak H, Vorderstrasse BA, Harrer N, Neruda W, Reichel C, Woisetschlager M. Activation of the aryl hydrocarbon receptor is essential for mediating the anti-inflammatory effects of a novel low molecular weight compound. Blood 112: 1158-1165 (2008). *

• Lazarczyk M, Grzela K, Grzela T. Immunostimulatory oligonucleotides in therapy of allergic diseases. Expert Opin. Biol. Ther. 5: 525-536 (2005).

• Lazebnik LB, Chernutskaia SP, Gervazieva VB, Sukhareva GV. H. pylori in development of allergic diseases in patients with gastroduodenal diseases. Ter. Arkh. 80: 63-66 (2008).

• Le AV, Broide DH. Indoleamine-2,3-dioxygenase modulation of allergic immune responses. Curr. Allergy Asthma Rep. 6: 27-31 (2006).

• Le GT, Abbenante G. Inhibitors of TACE and caspase-1 as anti-inflammatory drugs. Curr. Med. Chem. 12: 2963-2977 (2005).

• Le Souef PN, Candelaria P, Goldblatt J. Evolution and respiratory genetics. Eur. Respir. J. 28: 1258-1263 (2006).

• Leb VM, Jahn-Schmid B, Schmetterer KG, Kueng HJ, Haiderer D, Neunkirchner A, Fischer GF, Nissler K, Hartl A, Thalhamer J, Bohle B, Seed B, Pickl WF. Molecular and functional analysis of the antigen receptor of Art v 1-specific helper T lymphocytes. J. Allergy Clin. Immunol. 121: 64-71 (2008). *

• Lebre MC, van Capel TM, Bos JD, Knol EF, Kapsenberg ML, de Jong EC. Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients. J. Allergy Clin. Immunol. 122: 969-976.e5 (2008). *

• Lee B, Trung Trinh H, Bae EA, Jung K, Kim DH. Mangiferin inhibits passive cutaneous anaphylaxis reaction and pruritus in mice. Planta Med. 75: 1415-1417 (2009).

• Lee CC, Lin WY, Wan L, Tsai Y, Tsai CH, Huang CM, Chen CP, Tsai FJ. Association of interleukin-18 gene polymorphism with asthma in Chinese patients. J. Clin. Lab. Anal. 22: 39-44 (2008). *

• Lee HC, Ziegler SF. Inducible expression of the proallergic cytokine thymic stromal lymphopoietin in airway epithelial cells is controlled by NFkappaB. Proc. Natl. Acad. Sci. U.S.A. 104: 914-919 (2007). *

• Lee HM, Park SA, Chung SW, Woo JS, Chae SW, Lee SH, Kang HJ, Hwang SJ. Interleukin-18/-607 gene polymorphism in allergic rhinitis. Int. J. Pediatr. Otorhinolaryngol. 70: 1085-1088 (2006).

• Lee JH, Kim JW, Ko NY, Mun SH, Her E, Kim BK, Han JW, Lee HY, Beaven MA, Kim YM, Choi WS. Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk. J. Allergy Clin. Immunol. 121: 1225-1231 (2008). *

• Lee JH, Kim JW, Ko NY, Mun SH, Kim DK, Kim JD, Won HS, Shin HS, Kim HS, Her E, Kim YM, Choi W. Mast cell-mediated allergic response is suppressed by Sophorae flos: inhibition of Src-family kinase. Exp. Biol. Med. (Maywood) 233: 1271-1279 (2008). *

• Lee JH, Yu HH, Wang LC, Yang YH, Lin YT, Chiang BL. The levels of CD4(+)CD25(+) regulatory T cells in paediatric patients with allergic rhinitis and bronchial asthma. Clin. Exp. Immunol. 148: 53-63 (2007). *

• Lee JS, Kim IS, Kim JH, Kim JS, Kim DH, Yun CY. Suppressive effects of Houttuynia cordata Thunb (Saururaceae) extract on Th2 immune response. J. Ethnopharmacol. 117: 34-40 (2008).

• Lee JS, Kim IS, Ryu JS, Yun CY. House dust mite, Dermatophagoides pteronissinus increases expression of MCP-1, IL-6, and IL-8 in human monocytic THP-1 cells. Cytokine 42: 365-371 (2008).

• Lee KS, Kim SR, Park SJ, Park HS, Min KH, Jin SM, Lee MK, Kim UH, Lee YC. Peroxisome proliferator activated receptor-gamma modulates reactive oxygen species generation and activation of nuclear factor-kappaB and hypoxia-inducible factor 1alpha in allergic airway disease of mice. J. Allergy Clin. Immunol. 118: 120-127 (2006). *

• Lee KS, Park SJ, Hwang PH, Yi HK, Song CH, Chai OH, Kim JS, Lee MK, Lee YC. PPAR-gamma modulates allergic inflammation through up-regulation of PTEN. FASEB J. 19: 1033-1035 (2005). *

• Lee M, Hodges WG, Huggins TL, Lee EL. Eosinophilic gastroenteritis. South. Med. J. 89: 189-194 (1996).

• Lee RW, Creed TJ, Schewitz LP, Newcomb PV, Nicholson LB, Dick AD, Dayan CM. CD4+CD25int T cells in inflammatory diseases refractory to treatment with glucocorticoids. J. Immunol. 179: 7941-7948 (2007). *

• Lee S, Park HH, Son HY, Ha JH, Lee MG, Oh TY, Sohn DH, Jeong TC, Lee SH, Son JK, Lee SG, Jun CD, Kim SH. DA-9601 inhibits activation of the human mast cell line HMC-1 through inhibition of NF-kappaB. Cell Biol. Toxicol. 23: 105-112 (2007). *

• Lee SH, Prince JE, Rais M, Kheradmand F, Shardonofsky F, Lu H, Beaudet AL, Smith CW, Soong L, Corry DB. Differential requirement for CD18 in T-helper effector homing. Nat. Med. 9: 1281-1286 (2003). *

• Lee SJ, Chinen J, Kavanaugh A. Immunomodulator therapy: monoclonal antibodies, fusion proteins, cytokines, and immunoglobulins. J. Allergy Clin. Immunol. 125: S314-S323 (2010). *

• Lee SJ, Kavanaugh A. Adverse reactions to biologic agents: focus on autoimmune disease therapies. J. Allergy Clin. Immunol. 116: 900-905 (2005). *

• Leech MD, Anderton SM. Antigen-based therapies targeting the expansion of regulatory T cells in autoimmune and allergic disease. Chem. Immunol. Allergy 94: 201-210 (2008).

• Leech MD, Chung CY, Culshaw A, Anderton SM. Peptide-based immunotherapy of experimental autoimmune encephalomyelitis without anaphylaxis. Eur. J. Immunol. 37: 3576-3581 (2007). *

• Legrand F, Driss V, Woerly G, Loiseau S, Hermann E, Fournie JJ, Heliot L, Mattot V, Soncin F, Gougeon ML, Dombrowicz D, Capron M. A functional gammadeltaTCR/CD3 complex distinct from gammadelta T cells is expressed by human eosinophils. PLoS One 4: e5926 (2009). *

• Lehrer SB, Ayuso R, Reese G. Seafood allergy and allergens: a review. Mar. Biotechnol. (N.Y.) 5: 339-348 (2003). *

• Lei Z, Liu G, Huang Q, Lv M, Zu R, Zhang GM, Feng ZH, Huang B. SCF and IL-31 rather than IL-17 and BAFF are potential indicators in patients with allergic asthma. Allergy 63: 327-332 (2008).

• Lelong J, Duburque C, Fournier C, Colombel JF, Desreumaux P, Tonnel AB, Wallaert B. Desensitisation to infliximab in patients with Crohn's disease. Rev. Mal. Respir. 22: 239-246 (2005).

• Lester LA, Rich SS, Blumenthal MN, Togias A, Murphy S, Malveaux F, Miller ME, Dunston GM, Solway J, Wolf RL, Samet JM, Marsh DG, Meyers DA, Ober C, Bleecker ER; Collaborative Study on the Genetics of Asthma. Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma. J. Allergy Clin. Immunol. 108: 357-362 (2001). *

• Leung PS, Chen YC, Chu KH. Seafood allergy: tropomyosins and beyond. J. Microbiol. Immunol. Infect. 32: 143-154 (1999).

• Leung PS, Chu KH. Molecular and immunological characterization of shellfish allergens. Front. Biosci. 3: d306-d312 (1998). *

• Leung TF, Liu EK, Li CY, Chan IH, Yung E, Lam CW, Wong GW. Lack of association between NOS2 pentanucleotide repeat polymorphism and asthma phenotypes or exhaled nitric oxide concentration. Pediatr. Pulmonol. 41: 649-655 (2006).

• Leung TF, Liu EK, Tang NL, Ko FW, Li CY, Lam CW, Wong GW. Nitric oxide synthase polymorphisms and asthma phenotypes in Chinese children. Clin. Exp. Allergy 35: 1288-1294 (2005). *

• Leung TF, Sy HY, Ng MC, Chan IH, Wong GW, Tang NL, Waye MM, Lam CW. Asthma and atopy are associated with chromosome 17q21 markers in Chinese children. Allergy 64: 621-628 (2009). *

• Leung TF, Tang NL, Chan IH, Li AM, Ha G, Lam CW. A polymorphism in the coding region of interleukin-13 gene is associated with atopy but not asthma in Chinese children. Clin. Exp. Allergy 31: 1515-1521 (2001). *

• Leung TF, Tang NL, Sung YM, Li CY, Ma SL, Lam CW, Wong GW. Genetic association study between mbl2 and asthma phenotypes in Chinese children. Pediatr. Allergy Immunol. 17: 501-507 (2006). *

• LeVan TD, Guerra S, Klimecki W, Vasquez MM, Lohman IC, Martinez FD, Halonen M, Wright AL. The impact of CD14 polymorphisms on the development of soluble CD14 levels during infancy. Genes Immun. 7: 77-80 (2006). *

• Levy BD, Kohli P, Gotlinger K, Haworth O, Hong S, Kazani S, Israel E, Haley KJ, Serhan CN. Protectin D1 is generated in asthma and dampens airway inflammation and hyperresponsiveness. J. Immunol. 178: 496-502 (2007). *

• Levy BD, Lukacs NW, Berlin AA, Schmidt B, Guilford WJ, Serhan CN, Parkinson JF. Lipoxin A4 stable analogs reduce allergic airway responses via mechanisms distinct from CysLT1 receptor antagonism. FASEB J. 21: 3877-3884 (2007). *

• Levy C, Lindor KD. Treatment options for primary biliary cirrhosis and primary sclerosing cholangitis. Curr. Treat. Options Gastroenterol. 6: 93-103 (2003).

• Lewkowich IP, Lajoie S, Clark JR, Herman NS, Sproles AA, Wills-Karp M. Allergen uptake, activation, and IL-23 production by pulmonary myeloid DCs drives airway hyperresponsiveness in asthma-susceptible mice. PLoS ONE 3: e3879 (2008). *

• Li B, Samanta A, Song X, Iacono KT, Brennan P, Chatila TA, Roncador G, Banham AH, Riley JL, Wang Q, Shen Y, Saouaf SJ, Greene MI. FOXP3 is a homo-oligomer and a component of a supramolecular regulatory complex disabled in the human XLAAD/IPEX autoimmune disease. Int. Immunol. 19: 825-835 (2007). *

• Li CS, Chae SC, Lee JH, Zhang Q, Chung HT. Identification of single nucleotide polymorphisms in FOXJ1 and their association with allergic rhinitis. J. Hum. Genet. 51: 292-297 (2006). *

• Li H, Nowak-Wegrzyn A, Charlop-Powers Z, Shreffler W, Chehade M, Thomas S, Roda G, Dahan S, Sperber K, Berin MC. Transcytosis of IgE-antigen complexes by CD23a in human intestinal epithelial cells and its role in food allergy. Gastroenterology 131: 47-58 (2006). *

• Li M, Luraghi P, Amour A, Qian XD, Carter PS, Clark CJ, Deakin A, Denyer J, Hobbs CI, Surby M, Patel VK, Schaefer EM. Kinetic assay for characterization of spleen tyrosine kinase activity and inhibition with recombinant kinase and crude cell lysates. Anal. Biochem. 384: 56-67 (2009). *

• Li X, Wills-Karp M, Ewart S. Investigating Gata3 as a positional candidate gene for allergic asthma in a murine model. Int. J. Immunogenet. 33: 333-337 (2006). *

• Li XD, Essayan DM, Liu MC, Beaty TH, Huang SK. Profiling of differential gene expression in activated, allergen-specific human Th2 cells. Genes Immun. 2: 88-98 (2001). *

• Li-Weber M, Krammer PH. Regulation of IL4 gene expression by T cells and therapeutic perspectives. Nat. Rev. Immunol. 3: 534-543 (2003). *

• Li1 CS, Zhang Q, Lim MK, Sheen DH, Shim SC, Kim JY, Lee SS, Yun KJ, Moon HB, Chung HT, Chae SC. Association of FOXJ1 polymorphisms with systemic lupus erythematosus and rheumatoid arthritis in Korean population. Exp. Mol. Med. 39: 805-811 (2007). *

• Liacouras CA. Eosinophilic esophagitis: treatment in 2005. Curr. Opin. Gastroenterol. 22: 147-152 (2006).

• Liacouras CA, Markowitz JE. Eosinophilic esophagitis: a subset of eosinophilic gastroenteritis. Curr. Gastroenterol. Rep. 1: 253-258 (1999).

• Liang XH, Cheung W, Heng CK, Wang DY. Absence of the Toll-like receptor 4 gene polymorphisms Asp299Gly and Thr399Ile in Singaporean Chinese. Ther. Clin. Risk Manag. 1: 243-246 (2005). *

• Lichtenegger FS, Kuerten S, Faas S, Boehm BO, Tary-Lehmann M, Lehmann PV. Dissociation of experimental allergic encephalomyelitis protective effect and allergic side reactions in tolerization with neuroantigen. J. Immunol. 178: 4749-4756 (2007). *

• Liden M, Kristjansson G, Valtysdottir S, Venge P, Hallgren R. Cow's milk protein sensitivity assessed by the mucosal patch technique is related to irritable bowel syndrome in patients with primary Sjogren's syndrome. Clin. Exp. Allergy 38: 929-935 (2008). *

• Lieto LD, Maasho K, West D, Borrego F, Coligan JE. The human CD94 gene encodes multiple, expressible transcripts including a new partner of NKG2A/B. Genes Immun. 7: 36-43 (2006). *

• Lim LH, Li HY, Huang CH, Lee BW, Lee YK, Chua KY. The effects of heat-killed wild-type Lactobacillus casei Shirota on allergic immune responses in an allergy mouse model. Int. Arch. Allergy Immunol. 148: 297-304 (2008).

• Lima JJ, Mohapatra S, Feng H, Lockey R, Jena PK, Castro M, Irvin C, Johnson JA, Wang J, Sylvester JE. A polymorphism in the NPPA gene associates with asthma. Clin. Exp. Allergy 38: 1117-1123 (2008). *

• Lindelof B, Granath F, Tengvall-Linder M, Lindelof H, Ekbom A. Allergy and autoimmune disease: a registry-based study. Clin. Exp. Allergy 39: 110-115 (2009). *

• Linden A. Interleukin-17 and airway remodelling. Pulm. Pharmacol. Ther. 19: 47-50 (2006).

• Lipozencic J. Keynote from Japan 5th Georg Rajka International Symposium on Atopic Dermatitis, Kyoto, May 11-13, 2008. Acta Dermatovenerol. Croat. 16: 168-169 (2008).

• Lipozencic J, Ljubojevic S. Langerhans' cells in dermatology. Arh. Hig. Rada. Toksikol. 55: 167-174 (2004).

• Lips KS, Luhrmann A, Tschernig T, Stoeger T, Alessandrini F, Grau V, Haberberger RV, Koepsell H, Pabst R, Kummer W. Down-regulation of the non-neuronal acetylcholine synthesis and release machinery in acute allergic airway inflammation of rat and mouse. Life Sci. 80: 2263-2269 (2007). *

• Listrom C, Holt K. Inflammatory bowel disease. Emerg. Med. 36: 24-28 (2004).

• Little FF, Cruikshank WW. Interleukin-16 and peptide derivatives as immunomodulatory therapy in allergic lung disease. Expert Opin. Biol. Ther. 4: 837-846 (2004).

• Liu C, Liu Z, Li Z, Wu Y. Molecular regulation of mast cell development and maturation. Mol. Biol. Rep. Jul 31 [Epub ahead of print] (2009). *

• Liu J, Divoux A, Sun J, Zhang J, Clement K, Glickman JN, Sukhova GK, Wolters PJ, Du J, Gorgun CZ, Doria A, Libby P, Blumberg RS, Kahn BB, Hotamisligil GS, Shi GP. Genetic deficiency and pharmacological stabilization of mast cells reduce diet-induced obesity and diabetes in mice. Nat. Med. 15: 940-945 (2009). *

• Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL. Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma. Immunology Aug 17 [Epub ahead of print] (2009). *

• Liu LY, Jarjour NN, Busse WW, Kelly EA. Chemokine receptor expression on human eosinophils from peripheral blood and bronchoalveolar lavage fluid after segmental antigen challenge. J. Allergy Clin. Immunol. 112: 556-562 (2003).

• Liu LY, Mathur SK, Sedgwick JB, Jarjour NN, Busse WW, Kelly EA. Human airway and peripheral blood eosinophils enhance Th1 and Th2 cytokine secretion. Allergy 61: 589-597 (2006). *

• Liu Q, Xia Y, Zhang W, Li J, Wang P, Li H, Wei C, Gong Y. A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han population. BMC Med. Genet. 10: 59 (2009). *

• Liu T, He SH, Zheng PY, Zhang TY, Wang BQ, Yang PC. Staphylococcal enterotoxin B increases TIM4 expression in human dendritic cells that drives naive CD4 T cells to differentiate into Th2 cells. Mol. Immunol. 44: 3580-3587 (2007). *

• Liu Z, Liu Q, Bleich D, Salgame P, Gause WC. Regulation of type 1 diabetes, tuberculosis, and asthma by parasites. J. Mol. Med. Oct 21 [Epub ahead of print] (2009). *

• Liu ZX, Kaplowitz N. Chapter 28. Immune mechanisms in drug-induced hepatotoxicity: therapeutic implications. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 363-374 (2007). *

• Ljungh A, Wadstrom T. Lactic acid bacteria as probiotics. Curr. Issues Intest. Microbiol. 7: 73-89 (2006).

• Llanes E, Quiralte J, Lopez E, Sastre B, Chacartegui M, Del Pozo V, Palomino P, Lahoz C, Cardaba B. Analysis of polymorphisms in olive pollen allergy: IL13, IL4RA, IL5 and ADRB2 genes. Int. Arch. Allergy Immunol. 148: 228-238 (2008).

• Llobet MP, Bertran JM, Espanol T. Common variable immunodeficiency in children. Allergol. Immunopathol. (Madr.) 30: 42-46 (2002).

• Lloyd CM, Hawrylowicz CM. Regulatory T cells in asthma. Immunity 31: 438-449 (2009). *

• Lobb RR, Adams SP. Small molecule antagonists of alpha4 integrins: novel drugs for asthma. Expert Opin. Investig. Drugs 8: 935-945 (1999).

• Lock R, Collingwood S, Ratcliffe A. Emerging therapies for respiratory diseases. Drug News Perspect. 20: 593-600 (2007).

• Lockard O Jr, Harmon C, Nolph K, Irvin W. Allergic reaction to allopurinol with cross-reactivity to oxypurinol. Ann. Intern. Med. 85: 333-335 (1976).

• Lohse AW, Hennes E. Diagnostic criteria for autoimmune hepatitis. Hepatol. Res. 37 Suppl. 3: S509 (2007). *

• Lomax AR, Calder PC. Probiotics, immune function, infection and inflammation: a review of the evidence from studies conducted in humans. Curr. Pharm. Des. 15: 1428-1518 (2009).

• Long AJ, McCarthy R, Rundell L, Goess C, Cuff CA. The efficacy of TNF blockade in asthma models depends on endotoxin levels in the allergic challenge. Proc. Am. Thorac. Soc. 6: 331-332 (2009). *

• Loscher T, Saathoff E. Eosinophilia during intestinal infection. Best Pract. Res. Clin. Gastroenterol. 22: 511-536 (2008).

• Louten J, Boniface K, de Waal Malefyt R. Development and function of TH17 cells in health and disease. J. Allergy Clin. Immunol. 123: 1004-1011 (2009). *

• Lovett-Racke AE, Racke MK. Retinoic acid promotes the development of Th2-like human myelin basic protein-reactive T cells. Cell. Immunol. 215: 54-60 (2002). *

• Lowe AJ, Thien FC, Stoney RM, Bennett CM, Hosking CS, Hill DJ, Carlin JB, Abramson MJ, Dharmage SC. Associations between fatty acids in colostrum and breast milk and risk of allergic disease. Clin. Exp. Allergy 38: 1745-1751 (2008). *

• Lowes MA, Chamian F, Abello MV, Leonardi C, Dummer W, Papp K, Krueger JG. Eruptive papules during efalizumab (anti-CD11a) therapy of psoriasis vulgaris: a case series. BMC Dermatol. 7: 2 (2007). *

• Lu B. The molecular mechanisms that control function and death of effector CD4+ T cells. Immunol. Res. 36: 275-282 (2006). *

• Lu C, Pelech S, Zhang H, Bond J, Spach K, Noubade R, Blankenhorn EP, Teuscher C. Pertussis toxin induces angiogenesis in brain microvascular endothelial cells. J. Neurosci. Res. 86: 2624-2640 (2008).

• Lu D, Vemuri VK, Duclos RI Jr, Makriyannis A. The cannabinergic system as a target for anti-inflammatory therapies. Curr. Top. Med. Chem. 6: 1401-1426 (2006).

• Lu TX, Munitz A, Rothenberg ME. MicroRNA-21 is up-regulated in allergic airway inflammation and regulates IL-12p35 expression. J. Immunol. 182: 4994-5002 (2009).

• Lue KH, Ku MS, Li C, Sun HL, Lee HS, Chou MC. ACE gene polymorphism might disclose why some Taiwanese children with allergic rhinitis develop asthma symptoms but others do not. Pediatr. Allergy Immunol. 17: 508-513 (2006). *

• Luft C, Hausding M, Finotto S. Regulation of T cells in asthma: implications for genetic manipulation. Curr. Opin. Allergy Clin. Immunol. 4: 69-74 (2004).

• Luger TA, Brzoska T. alpha-MSH related peptides: a new class of anti-inflammatory and immunomodulating drugs. Ann. Rheum. Dis. 66 Suppl. 3: iii52-iii55 (2007).

• Luisetti M, Franco Pignatti P. Genetics of idiopathic disseminated bronchiectasis. Semin. Respir. Crit. Care Med. 24: 179-184 (2003).

• Lull C, Wichers HJ, Savelkoul HF. Antiinflammatory and immunomodulating properties of fungal metabolites. Mediators Inflamm. 2005: 63-80 (2005). *

• Lundequist A, Nallamshetty SN, Xing W, Feng C, Laidlaw TM, Uematsu S, Akira S, Boyce JA. Prostaglandin E2 exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation. J. Immunol. 184: 433-441 (2010).

• Lyons A, O'Mahony D, O'Brien F, Macsharry J, Sheil B, Ceddia M, Russell WM, Forsythe P, Bienenstock J, Kiely B, Shanahan F, O'Mahony L. Bacterial strain-specific induction of Foxp3(+) T regulatory cells is protective in murine allergy models. Clin. Exp. Allergy Jan 11 [Epub ahead of print] (2010). *

• Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ. Human corneal epithelium-derived thymic stromal lymphopoietin - a potential link between the innate and adaptive immune responses via Toll-like receptors and Th2 cytokines. Invest. Ophthalmol. Vis. Sci. 50: 2702-2709 (2009). *

• Ma Y, Ma AG, Peng Z. A potential immunotherapy approach: mucosal immunization with an IL-13 peptide-based virus-like particle vaccine in a mouse asthma model. Vaccine 25: 8091-8099 (2007). *

• Mabalirajan U, Dinda AK, Sharma SK, Ghosh B. Esculetin restores mitochondrial dysfunction and reduces allergic asthma features in experimental murine model. J. Immunol. 183: 2059-2067 (2009).

• Mackay IR. Hepatoimmunology: a perspective. Immunol. Cell Biol. 80: 36-44 (2002). *

• Maddur MS, Kaveri SV, Bayry J. Basophils as antigen presenting cells. Trends Immunol. 31: 45-48 (2010). *

• Madsen C. Prevalence of food allergy: an overview. Proc. Nutr. Soc. 64: 413-417 (2005). *

• Madsen JR, Laursen LS, Lauritsen K. Chronic inflammatory bowel disease - current status. Ugeskr. Laeger. 154: 2243-2250 (1992).

• Maggi L, Santarlasci V, Liotta F, Frosali F, Angeli R, Cosmi L, Maggi E, Romagnani S, Annunziato F. Demonstration of circulating allergen-specific CD4+CD25highFoxp3+ T-regulatory cells in both nonatopic and atopic individuals. J. Allergy Clin. Immunol. 120: 429-436 (2007). *

• Mahr A, Artigues N, Coste J, Aouba A, Pagnoux C, Guillevin L; French Vasculitis Study Group. Seasonal variations in onset of Wegener's granulomatosis: increased in summer? J. Rheumatol. 33: 1615-1622 (2006).

• Maintz L, Novak N. Histamine and histamine intolerance. Am. J. Clin. Nutr. 85: 1185-1196 (2007). *

• Maizels RM. Infections and allergy - helminths, hygiene and host immune regulation. Curr. Opin. Immunol. 17: 656-661 (2005).

• Majorczyk E, Jasek M, Ploski R, Wagner M, Kosior A, Pawlik A, Obojski A, Luszczek W, Nowak I, Wisniewski A, Kusnierczyk P. Association of PTPN22 single nucleotide polymorphism with rheumatoid arthritis but not with allergic asthma. Eur. J. Hum. Genet. 15: 1043-1048 (2007). *

• Malfitano AM, Matarese G, Bifulco M. From cannabis to endocannabinoids in multiple sclerosis: a paradigm of central nervous system autoimmune diseases. Curr. Drug Targets CNS Neurol. Disord. 4: 667-675 (2005).

• Mamessier E, Botturi K, Vervloet D, Magnan A. T regulatory lymphocytes, atopy and asthma: a new concept in three dimensions. Rev. Mal. Respir. 22: 305-311 (2005).

• Mamessier E, Milhe F, Guillot C, Birnbaum J, Dupuy P, Lorec AM, Vervloet D, Magnan A. T-cell activation in occupational asthma and rhinitis. Allergy 62: 162-169 (2007). *

• Maneechotesuwan K, Yao X, Ito K, Jazrawi E, Usmani OS, Adcock IM, Barnes PJ. Suppression of GATA-3 nuclear import and phosphorylation: a novel mechanism of corticosteroid action in allergic disease. PLoS Med. 6: e1000076 (2009). *

• Mangan NE, Fallon RE, Smith P, van Rooijen N, McKenzie AN, Fallon PG. Helminth infection protects mice from anaphylaxis via IL-10-producing B cells. J. Immunol. 173: 6346-6356 (2004). *

• Manguso F, Sanges M, Staiano T, Gargiulo S, Nastro P, Gargano D, Somma P, Mansueto G, Peluso R, Scarpa R, D'Armiento FP, Astarita C, Ayala F, Renda A, Mazzacca G, D'Arienzo A. Cigarette smoking and appendectomy are risk factors for extraintestinal manifestations in ulcerative colitis. Am. J. Gastroenterol. 99: 327-334 (2004). *

• Maniscalco M, Sofia M, Pelaia G. Nitric oxide in upper airways inflammatory diseases. Inflamm. Res. 56: 58-69 (2007). *

• Manns MP, Wiegand J. Novel approaches to the treatment of autoimmune hepatitis. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 67-70 (2004). *

• Mansson A, Cardell LO. Role of atopic status in Toll-like receptor (TLR)7- and TLR9-mediated activation of human eosinophils. J. Leukoc. Biol. 85: 719-727 (2009). *

• Mantelli F, Lambiase A, Bonini S. A simple and rapid diagnostic algorithm for the detection of ocular allergic diseases. Curr. Opin. Allergy Clin. Immunol. 9: 471-476 (2009).

• Mao TK, Van de Water J, Gershwin ME. Effects of a Spirulina-based dietary supplement on cytokine production from allergic rhinitis patients. J. Med. Food 8: 27-30 (2005).

• Maret M, Ruffie C, Periquet B, Campo AM, Menevret M, Phelep A, Dziewiszek K, Druilhe A, Pretolani M. Liposomal retinoic acids modulate asthma manifestations in mice. J. Nutr. 137: 2730-2736 (2007). *

• Mari A. Is there a causative role for tetanus toxoid vaccination in the development of allergy-like symptoms and in the increasing prevalence of atopic diseases? Med. Hypotheses 63: 875-886 (2004).

• Mari JY, Guy C, Beyens MN, Ollagnier M. Delayed drug-induced hepatic injury. Evoking the role of amoxicillin-clavulinic acid combination. Therapie 55: 699-704 (2000).

• Mark BJ, Beaty AD, Slavin RG. Are fish oil supplements safe in finned fish-allergic patients? Allergy Asthma Proc. 29: 528-529 (2008).

• Markova T, Chuvirov D. Frequently ill children. Adv. Exp. Med. Biol. 601: 301-306 (2007).

• Marks GB. Environmental factors and gene-environment interactions in the aetiology of asthma. Clin. Exp. Pharmacol. Physiol. 33: 285-289 (2006).

• Marks GB, Mihrshahi S, Kemp AS, Tovey ER, Webb K, Almqvist C, Ampon RD, Crisafulli D, Belousova EG, Mellis CM, Peat JK, Leeder SR; for the Childhood Asthma Prevention Study team. Prevention of asthma during the first 5 years of life: a randomized controlled trial. J. Allergy Clin. Immunol. 118: 53-61 (2006). *

• Marmont AM. Stem cell transplantation for severe autoimmune diseases: progress and problems. Haematologica 83: 733-743 (1998). *

• Marone G, Spadaro G, Palumbo C, Condorelli G. The anti-IgE/anti-FcepsilonRIalpha autoantibody network in allergic and autoimmune diseases. Clin. Exp. Allergy 29: 17-27 (1999). *

• Marone G, Triggiani M, de Paulis A. Mast cells and basophils: friends as well as foes in bronchial asthma? Trends Immunol. 26: 25-31 (2005). *

• Marques-Deak A, Cizza G, Sternberg E. Brain-immune interactions and disease susceptibility. Mol. Psychiatry 10: 239-250 (2005).

• Marschan E, Kuitunen M, Kukkonen K, Poussa T, Sarnesto A, Haahtela T, Korpela R, Savilahti E, Vaarala O. Probiotics in infancy induce protective immune profiles that are characteristic for chronic low-grade inflammation. Clin. Exp. Allergy 38: 611-618 (2008). *

• Marshall JS. Mast-cell responses to pathogens. Nat. Rev. Immunol. 4: 787-799 (2004). *

• Martin A, Gallino N, Gagliardi J, Ortiz S, Lascano AR, Diller A, Daraio MC, Kahn A, Mariani AL, Serra HM. Early inflammatory markers in elicitation of allergic contact dermatitis. BMC Dermatol. 2: 9 (2002). *

• Martin H. Role of PPAR-gamma in inflammation. Prospects for therapeutic intervention by food components. Mutat. Res. 669: 1-7 (2009).

• Martin SF. T lymphocyte-mediated immune responses to chemical haptens and metal ions: implications for allergic and autoimmune disease. Int. Arch. Allergy Immunol. 134: 186-198 (2004).

• Martin SF, Dudda JC, Bachtanian E, Lembo A, Liller S, Durr C, Heimesaat MM, Bereswill S, Fejer G, Vassileva R, Jakob T, Freudenberg N, Termeer CC, Johner C, Galanos C, Freudenberg MA. Toll-like receptor and IL-12 signaling control susceptibility to contact hypersensitivity. J. Exp. Med. 205: 2151-2162 (2008). *

• Martin-Mateos MA. Monoclonal antibodies in pediatrics: use in prevention and treatment. Allergol. Immunopathol. (Madr.) 35: 145-150 (2007).

• Martinez Albaladejo M, Alguacil Garcia G, Gonzalez Pina B, de Paco Moya M, Herranz Marin T, Moreno-Requena J. Eosinophilic gastroenteritis, apropos a new case. An. Med. Interna 14: 187-189 (1997).

• Martinez FD. CD14, endotoxin, and asthma risk: actions and interactions. Proc. Am. Thorac. Soc. 4: 221-225 (2007). *

• Martinez S, Heyneman LE, McAdams HP, Rossi SE, Restrepo CS, Eraso A. Mucoid impactions: finger-in-glove sign and other CT and radiographic features. Radiographics 28: 1369-1382 (2008). *

• Martinez-Montiel MP, Munoz-Yague MT. Biologic therapies for chronic inflammatory bowel disease. Rev. Esp. Enferm. Dig. 98: 265-291 (2006).

• Martino DJ, Prescott SL. Silent mysteries: epigenetic paradigms could hold the key to conquering the epidemic of allergy and immune disease. Allergy 65: 7-15 (2010). *

• Masaki Y, Dong L, Kurose N, Kitagawa K, Morikawa Y, Yamamoto M, Takahashi H, Shinomura Y, Imai K, Saeki T, Azumi A, Nakada S, Sugiyama E, Matsui S, Origuchi T, Nishiyama S, Nishimori I, Nojima T, Yamada K, Kawano M, Zen Y, Kaneko M, Miyazaki K, et al. Proposal for a new clinical entity, IgG4-positive multi-organ lymphoproliferative syndrome: analysis of 64 cases of IgG4-related disorders. Ann. Rheum. Dis. 68: 1310-1315 (2009).

• Mastrandrea F, Semeraro FP, Coradduzza G, Manelli M, Scarcia G, Pezzuto F, Serio G. CD34+ hemopoietic precursor and stem cells traffic in peripheral blood of celiac patients is significantly increased but not directly related to epithelial damage severity. Eur. Ann. Allergy Clin. Immunol. 40: 90-103 (2008).

• Masuda A, Nakamura A, Maeda T, Sakamoto Y, Takai T. Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation. J. Exp. Med. 204: 907-920 (2007). *

• Matangkasombut P, Pichavant M, Dekruyff RH, Umetsu DT. Natural killer T cells and the regulation of asthma. Mucosal Immunol. 2: 383-392 (2009). *

• Matheu V, Berggard K, Barrios Y, Barrios Y, Arnau MR, Zubeldia JM, Baeza ML, Back O, Issazadeh-Navikas S. Impact on allergic immune response after treatment with retinoic acid. Nutr. Metab. (Lond.) 6: 44 (2009). *

• Matricardi PM, Ronchetti R. Are infections protecting from atopy? Curr. Opin. Allergy Clin. Immunol. 1: 413-419 (2001).

• Matsoukas J, Apostolopoulos V, Kalbacher H, Papini AM, Tselios T, Chatzantoni K, Biagioli T, Lolli F, Deraos S, Papathanassopoulos P, Troganis A, Mantzourani E, Mavromoustakos T, Mouzaki A. Design and synthesis of a novel potent myelin basic protein epitope 87-99 cyclic analogue: enhanced stability and biological properties of mimics render them a potentially new class of immunomodulators. J. Med. Chem. 48: 1470-1480 (2005). *

• Matsukuma E, Kato Z, Omoya K, Hashimoto K, Li A, Yamamoto Y, Ohnishi H, Hiranuma H, Komine H, Kondo N. Development of fluorescence-linked immunosorbent assay for high throughput screening of interferon-gamma. Allergol. Int. 55: 49-54 (2006). *

• Matsumoto T, Tanaka T, Kawase I. Infliximab for rheumatoid arthritis in a patient with tuberculosis. N. Engl. J. Med. 355: 740-741 (2006).

• Matz H. UV light and its interaction with cutaneous receptors. Dermatol. Clin. 25: 633-641 (2007).

• Mayer L. Mucosal immunity. Pediatrics 111: 1595-1600 (2003). *

• Mazmanian SK, Kasper DL. The love-hate relationship between bacterial polysaccharides and the host immune system. Nat. Rev. Immunol. 6: 849-858 (2006). *

• Mbitikon-Kobo FM, Vocanson M, Michallet MC, Tomkowiak M, Cottalorda A, Angelov GS, Coupet CA, Djebali S, Marcais A, Dubois B, Bonnefoy-Berard N, Nicolas JF, Arpin C, Marvel J. Characterization of a CD44/CD122int memory CD8 T cell subset generated under sterile inflammatory conditions. J. Immunol. 182: 3846-3854 (2009).

• McCall-Culbreath KD, Li Z, Zutter MM. Cross-talk between the alpha2beta1 integrin and c-met/HGF-R regulates innate immunity. Blood 111: 3562-3570 (2008). *

• McDevitt H. Specific antigen vaccination to treat autoimmune disease. Proc. Natl. Acad. Sci. U.S.A. 101: 14627-14630 (2004). *

• McDonald JR. Selective chemokine receptor-targeted depletion of pathological cells as a therapeutic strategy for inflammatory, allergic and autoimmune diseases. Recent Pat. Inflamm. Allergy Drug Discov. 3: 177-187 (2009).

• McGee HS, Stallworth AL, Agrawal T, Shao Z, Lorence L, Agrawal DK. Flt3-ligand decreases Th17 cells and SOCS proteins in the lung of house dust mite-sensitized and challenged mice. Am. J. Respir. Cell. Mol. Biol. Nov 20 [Epub ahead of print] (2009). *

• McIntire JJ, Umetsu DT, DeKruyff RH. TIM-1, a novel allergy and asthma susceptibility gene. Springer Semin. Immunopathol. 25: 335-348 (2004). *

• McKenzie BS, Kastelein RA, Cua DJ. Understanding the IL-23-IL-17 immune pathway. Trends Immunol. 27: 17-23 (2006). *

• McPherson VA, Sharma N, Everingham S, Smith J, Zhu HH, Feng GS, Craig AW. SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes FcvarepsilonRI-induced activation of Fyn and Erk pathways leading to TNFalpha release from bone marrow-derived mast cells. J. Immunol. 183: 4940-4947 (2009).

• Medoff BD, Thomas SY, Luster AD. T cell trafficking in allergic asthma: the ins and outs. Annu. Rev. Immunol. 26: 205-232 (2008). *

• Mehlman MA. Dangerous and cancer-causing properties of products and chemicals in the oil-refining and petrochemical industry. Part XXII: Health hazards from exposure to gasoline containing methyl tertiary butyl ether: study of New Jersey residents. Toxicol. Ind. Health 12: 613-627 (1996).

• Mekala DJ, Alli RS, Geiger TL. IL-10-dependent infectious tolerance after the treatment of experimental allergic encephalomyelitis with redirected CD4+CD25+ T lymphocytes. Proc. Natl. Acad. Sci. U.S.A. 102: 11817-11822 (2005). *

• Mekala DJ, Alli RS, Geiger TL. IL-10-dependent suppression of experimental allergic encephalomyelitis by Th2-differentiated, anti-TCR redirected T lymphocytes. J. Immunol. 174: 3789-3797 (2005). *

• Mekala DJ, Geiger TL. Immunotherapy of autoimmune encephalomyelitis with re-directed CD4+CD25+ T-lymphocytes. Blood 105: 2090-2092 (2005). *

• Meknache N, Jonsson F, Laurent J, Guinnepain MT, Daeron M. Human basophils express the glycosylphosphatidylinositol-anchored low-affinity IgG receptor FcgammaRIIIB (CD16B). J. Immunol. 182: 2542-2550 (2009).

• Melen E, Nyberg F, Lindgren CM, Berglind N, Zucchelli M, Nordling E, Hallberg J, Svartengren M, Morgenstern R, Kere J, Bellander T, Wickman M, Pershagen G. Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease. Environ. Health Perspect. 116: 1077-1084 (2008).

• Melgert BN, Timens W, Kerstjens HA, Geerlings M, Luinge MA, Schouten JP, Postma DS, Hylkema MN. Effects of 4 months of smoking in mice with ovalbumin-induced airway inflammation. Clin. Exp. Allergy 37: 1798-1808 (2007). *

• Melnik BC. Milk - the promoter of chronic Western diseases. Med. Hypotheses 72: 631-639 (2009).

• Melo N, Morais A, Alves H, Lima B, Tafulo S, Goncalves R. HLA - A, -C, -B, -DRB1 e -DQB polymorphisms in extrinsic allergic alveolitis (EAA). Rev. Port. Pneumol. 11: S29 (2005).

• Menard O, Butel MJ, Gaboriau-Routhiau V, Waligora-Dupriet AJ. Gnotobiotic mouse immune response induced by Bifidobacterium sp. strains isolated from infants. Appl. Environ. Microbiol. 74: 660-666 (2008).

• Meng JF, McFall C, Rosenwasser LJ. Polymorphism R62W results in resistance of CD23 to enzymatic cleavage in cultured cells. Genes Immun. 8: 215-223 (2007). *

• Mengel J, Favaro P, Meyer A, Motta V, de Alencar R, Postol E, Cardillo F. Potentiation of immunological tolerance induction in adult mice by co-administration of pooled normal IgG and oral tolerogens: a potential therapeutic approach for autoimmune diseases. Med. Hypotheses 64: 978-985 (2005).

• Mengheri E. Health, probiotics, and inflammation. J. Clin. Gastroenterol. 42 Suppl. 3 Pt. 2: S177-S178 (2008).

• Mercer N, Guzman L, Cueto Rua E, Drut R, Ahmed H, Vasta GR, Toscano MA, Rabinovich GA, Docena GH. Duodenal intraepithelial lymphocytes of children with cow milk allergy preferentially bind the glycan-binding protein galectin-3. Int. J. Immunopathol. Pharmacol. 22: 207-217 (2009).

• Metz M, Maurer M. Innate immunity and allergy in the skin. Curr. Opin. Immunol. 21: 687-693 (2009).

• Metz M, Maurer M. Mast cells - key effector cells in immune responses. Trends Immunol. 28: 234-241 (2007). *

• Metzger K, Fremont M, Roelant C, De Meirleir K. Lower frequency of IL-17F sequence variant (His161Arg) in chronic fatigue syndrome patients. Biochem. Biophys. Res. Commun. 376: 231-233 (2008). *

• Meyer EH, DeKruyff RH, Umetsu DT. iNKT cells in allergic disease. Curr. Top. Microbiol. Immunol. 314: 269-291 (2007).

• Meylan F, Davidson TS, Kahle E, Kinder M, Acharya K, Jankovic D, Bundoc V, Hodges M, Shevach EM, Keane-Myers A, Wang EC, Siegel RM. The TNF-family receptor DR3 is essential for diverse T cell-mediated inflammatory diseases. Immunity 29: 79-89 (2008). *

• Meyts I, Hellings PW, Hens G, Vanaudenaerde BM, Verbinnen B, Heremans H, Matthys P, Bullens DM, Overbergh L, Mathieu C, De Boeck K, Ceuppens JL. IL-12 contributes to allergen-induced airway inflammation in experimental asthma. J. Immunol. 177: 6460-6470 (2006). *

• Miescher SM, Vogel M. Molecular aspects of allergy. Mol. Aspects Med. 23: 413-462 (2002).

• Miheller P, Lakatos PL, Horvath G, Molnar T, Szamosi T, Cegledi Z, Salamon A, Czimmer J, Rumi G, Palatka K, Papp M, Jakab Z, Szabo A, Gelley A, Lakatos L, Barta Z, Balazs C, Racz I, Zeher M, Dobronte Z, Altorjay I, Hunyady B, Simon L, Papp J, et al. Efficacy and safety of infliximab induction therapy in Crohn's disease in Central Europe - a Hungarian nationwide observational study. BMC Gastroenterol. 9: 66 (2009). *

• Mikol DD, Ditlow C, Usatin D, Biswas P, Kalbfleisch J, Milner A, Calenoff E. Serum IgE reactive against small myelin protein-derived peptides is increased in multiple sclerosis patients. J. Neuroimmunol. 180: 40-49 (2006).

• Milkova L, Voelcker V, Forstreuter I, Sack U, Anderegg U, Simon JC, Maier-Simon C. The NF-kappaB signalling pathway is involved in the LPS/IL-2-induced upregulation of FoxP3 expression in human CD4CD25 regulatory T cells. Exp. Dermatol. Oct 21 [Epub ahead of print] (2009).

• Miller AL. The etiologies, pathophysiology, and alternative/complementary treatment of asthma. Altern. Med. Rev. 6: 20-47 (2001). *

• Miller PW, Hamosh A, Macek M Jr, Greenberger PA, MacLean J, Walden SM, Slavin RG, Cutting GR. Cystic fibrosis transmembrane conductance regulator (CFTR) gene mutations in allergic bronchopulmonary aspergillosis. Am. J. Hum. Genet. 59: 45-51 (1996). *

• Milner JD, Ward JM, Keane-Myers A, Paul WE. Lymphopenic mice reconstituted with limited repertoire T cells develop severe, multiorgan, Th2-associated inflammatory disease. Proc. Natl. Acad. Sci. U.S.A. 104: 576-581 (2007). *

• Min YD, Choi CH, Bark H, Son HY, Park HH, Lee S, Park JW, Park EK, Shin HI, Kim SH. Quercetin inhibits expression of inflammatory cytokines through attenuation of NF-kappaB and p38 MAPK in HMC-1 human mast cell line. Inflamm. Res. 56: 210-215 (2007). *

• Minocha A. Probiotics for preventive health. Nutr. Clin. Pract. 24: 227-241 (2009).

• Mirshahpanah P, Li YY, Burkhardt N, Asadullah K, Zollner TM. CCR4 and CCR10 ligands play additive roles in mouse contact hypersensitivity. Exp. Dermatol. 17: 30-34 (2008).

• Mishra B, Praharaj SK, Prakash R, Sinha VK. Aripiprazole-induced acneiform eruption. Gen. Hosp. Psychiatry 30: 479-481 (2008).

• Miyake S. iNKT cells, a friend or a foe for autoimmune disease and allergy? Nihon Rinsho Meneki Gakkai Kaishi 29: 27-36 (2006). *

• Miyake Y, Sasaki S, Arakawa M, Tanaka K, Murakami K, Ohya Y. Fatty acid intake and asthma symptoms in Japanese children: The Ryukyus Child Health Study. Clin. Exp. Allergy 38: 1644-1650 (2008). *

• Miyake Y, Sasaki S, Tanaka K, Ohya Y, Matsunaga I, Yoshida T, Hirota Y, Oda H. Relationship between dietary fat and fish intake and the prevalence of atopic eczema in pregnant Japanese females: baseline data from the Osaka Maternal and Child Health Study. Asia Pac. J. Clin. Nutr. 17: 612-619 (2008).

• Miyamasu M, Sekiya T, Ohta K, Ra C, Yoshie O, Yamamoto K, Tsuchiya N, Tokunaga K, Hirai K. Variations in the human CC chemokine eotaxin gene. Genes Immun. 2: 461-463 (2001). *

• Miyazawa M, Ito Y, Kosaka N, Nukada Y, Sakaguchi H, Suzuki H, Nishiyama N. Role of TNF-alpha and extracellular ATP in THP-1 cell activation following allergen exposure. J. Toxicol. Sci. 33: 71-83 (2008). *

• Miyazawa M, Ito Y, Kosaka N, Nukada Y, Sakaguchi H, Suzuki H, Nishiyama N. Role of MAPK signaling pathway in the activation of dendritic type cell line, THP-1, induced by DNCB and NiSO(4). J. Toxicol. Sci. 33: 51-59 (2008). *

• Mizoguchi Y, Miyajima K, Sakagami Y, Kobayashi K, Arai T, Fukamachi I, Yamammoto S, Morisawa S. Detection of the cholestatic factor in the liver tissue of patients with acute intrahepatic cholestasis. Gastroenterol. Jpn. 22: 331-336 (1987).

• Mizoguchi Y, Miyajima K, Sakagami Y, Yamamoto S, Morisawa S. Detection of the cholestatic factor in the liver tissue of patients with acute intrahepatic cholestasis. Ann. Allergy 56: 304-307 (1986).

• Mizrachi K, Aricha R, Feferman T, Kela-Madar N, Mandel I, Paperna T, Miller A, Ben-Nun A, Berrih-Aknin S, Souroujon MC, Fuchs S. Involvement of phosphodiesterases in autoimmune diseases. J. Neuroimmunol. Jan 23 [Epub ahead of print] (2010).

• Mizutani N, Nabe T, Yoshino S. Complement C3a regulates late asthmatic response and airway hyperresponsiveness in mice. J. Immunol. 183: 4039-4046 (2009).

• Mo C, Chearwae W, O'Malley JT, Adams SM, Kanakasabai S, Walline CC, Stritesky GL, Good SR, Perumal NB, Kaplan MH, Bright JJ. Stat4 isoforms differentially regulate inflammation and demyelination in experimental allergic encephalomyelitis. J. Immunol. 181: 5681-5690 (2008). *

• Mobs C, Slotosch C, Loffler H, Jakob T, Hertl M, Pfutzner W. Birch pollen immunotherapy leads to differential induction of regulatory T cells and delayed helper T cell immune deviation. J. Immunol. Jan 4 [Epub ahead of print] (2010).

• Moisan J, Camateros P, Thuraisingam T, Marion D, Koohsari H, Martin P, Boghdady ML, Ding A, Gaestel M, Guiot MC, Martin JG, Radzioch D. TLR7 ligand prevents allergen-induced airway hyperresponsiveness and eosinophilia in allergic asthma by a MYD88-dependent and MK2-independent pathway. Am. J. Physiol. Lung Cell. Mol. Physiol. 290: L987-L995 (2006). *

• Moisan J, Grenningloh R, Bettelli E, Oukka M, Ho IC. Ets-1 is a negative regulator of Th17 differentiation. J. Exp. Med. 204: 2825-2835 (2007). *

• Moisan J, Thuraisingam T, Henault J, Sanctis JD, Radzioch D. Role of SLC11A1 (formerly NRAMP1) in regulation of signal transduction induced by Toll-like receptor 7 ligands. FEMS Immunol. Med. Microbiol. 47: 138-147 (2006). *

• Moisini I, Nguyen P, Fugger L, Geiger TL. Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J. Immunol. 180: 3601-3611 (2008). *

• Mondal S, Roy A, Pahan K. Functional blocking monoclonal antibodies against IL-12p40 homodimer inhibit adoptive transfer of experimental allergic encephalomyelitis. J. Immunol. 182: 5013-5023 (2009).

• Monney L, Sabatos CA, Gaglia JL, Ryu A, Waldner H, Chernova T, Manning S, Greenfield EA, Coyle AJ, Sobel RA, Freeman GJ, Kuchroo VK. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 415: 536-541 (2002). *

• Montague P, McCallion AS, Davies RW, Griffiths IR. Myelin-associated oligodendrocytic basic protein: a family of abundant CNS myelin proteins in search of a function. Dev. Neurosci. 28: 479-487 (2006).

• Montgomery EH, Kroeger DC. Use of antibiotics in dental practice. Dent. Clin. North Am. 28: 433-453 (1984).

• Morard I, Hadengue A. Drug induced diarrhea. Rev. Med. Suisse. 4: 1867-1868, 1870-1872 (2008).

• Morel E, Bellon T. Amoxicillin conjugates to HLA class I molecules and interferes with signalling through the ILT2/LIR-1/CD85j inhibitory receptor. Allergy 62: 190-196 (2007). *

• Morfín Maciel BM, Castillo Morfín BM. Scleroderma related to specific immunotherapy. A report of a case. Rev. Alerg. Mex. 56: 136-145 (2009).

• Morgan AW, Hale G, Rebello PR, Richards SJ, Gooi HC, Waldmann H, Emery P, Isaacs JD. A pilot study of combination anti-cytokine and anti-lymphocyte biological therapy in rheumatoid arthritis. QJM 101: 299-306 (2008).

• Morgan R, Gao G, Pawling J, Dennis JW, Demetriou M, Li B. N-acetylglucosaminyltransferase V (Mgat5)-mediated N-glycosylation negatively regulates Th1 cytokine production by T cells. J. Immunol. 173: 7200-7208 (2004). *

• Mori A, Kaminuma O, Ogawa K, Nakata A, Egan RW, Akiyama K, Okudaira H. Control of IL-5 production by human helper T cells as a treatment for eosinophilic inflammation: comparison of in vitro and in vivo effects between selective and nonselective cytokine synthesis inhibitors. J. Allergy Clin. Immunol. 106: S58-S64 (2000).

• Mori A, Suko M, Kaminuma O, Inoue S, Ohmura T, Nishizaki Y, Nagahori T, Asakura Y, Hoshino A, Okumura Y, Sato G, Ito K, Okudaira H. IL-15 promotes cytokine production of human T helper cells. J. Immunol. 156: 2400-2405 (1996).

• Mori H, Yamanaka K, Kaketa M, Tamada K, Hakamada A, Isoda K, Yamanishi K, Mizutani H. Drug eruption caused by azathioprine: value of using the drug-induced lymphocytes stimulation test for diagnosis. J. Dermatol. 31: 731-736 (2004).

• Morioka Y, Yamasaki K, Leung D, Gallo RL. Cathelicidin antimicrobial peptides inhibit hyaluronan-induced cytokine release and modulate chronic allergic dermatitis. J. Immunol. 181: 3915-3922 (2008). *

• Morozov A, Applegate KE, Brown S, Howenstine M. High-attenuation mucus plugs on MDCT in a child with cystic fibrosis: potential cause and differential diagnosis. Pediatr. Radiol. 37: 592-595 (2007). *

• Morris SC, Orekhova T, Meadows MJ, Heidorn SM, Yang J, Finkelman FD. IL-4 induces in vivo production of IFN-gamma by NK and NKT cells. J. Immunol. 176: 5299-5305 (2006). *

• Mortaz E, Redegeld FA, Dunsmore K, Odoms K, Wong HR, Nijkamp FP, Engels F. Stimulation of cysteinyl leukotriene production in mast cells by heat shock and acetylsalicylic acid. Eur. J. Pharmacol. 561: 214-219 (2007). *

• Moses S. Pruritus. Am. Fam. Physician 68: 1135-1142 (2003). *

• Mottu A, Rubbia-Brandt L, Bihl F, Hadengue A, Spahr L. Acute hepatitis due to brivudin: a case report. J. Hepatol. 51: 967-969 (2009).

• Movahedi M, Moin M, Gharagozlou M, Aghamohammadi A, Dianat S, Moradi B, Nicknam MH, Nikbin B, Amirzargar A. Association of HLA class II alleles with childhood asthma and total IgE levels. Iran J. Allergy Asthma Immunol. 7: 215-220 (2008).

• Moy L, Levine J. Wireless capsule endoscopy in the pediatric age group: experience and complications. J. Pediatr. Gastroenterol. Nutr. 44: 516-520 (2007). *

• Mozena JD, Tinana A, Negri J, Steinke JW, Borish L. Lack of a role for cross-reacting anti-thyroid antibodies in chronic idiopathic urticaria. J. Invest. Dermatol. Feb 25 [Epub ahead of print] (2010). *

• Mueller C, Braag SA, Martino AT, Tang Q, Campbell-Thompson M, Flotte TR. The pros and cons of immunomodulatory IL-10 gene therapy with recombinant AAV in a Cftr(-/-)-dependent allergy mouse model. Gene Ther. 16: 172-183 (2009).

• Mueller C, Keeler A, Braag S, Menz T, Tang Q, Flotte TR. Modulation of exaggerated-IgE allergic responses by gene transfer-mediated antagonism of IL-13 and IL-17e. Mol. Ther. Nov 24 [Epub ahead of print] (2009).

• Mueller C, Torrez D, Braag S, Martino A, Clarke T, Campbell-Thompson M, Flotte TR. Partial correction of the CFTR-dependent ABPA mouse model with recombinant adeno-associated virus gene transfer of truncated CFTR gene. J. Gene Med. 10: 51-60 (2008).

• Mueller S. Classification of eosinophilic gastrointestinal diseases. Best Pract. Res. Clin. Gastroenterol. 22: 425-440 (2008).

• Mukherjee AB, Zhang Z, Chilton BS. Uteroglobin: a steroid-inducible immunomodulatory protein that founded the secretoglobin superfamily. Endocr. Rev. 28: 707-725 (2007).

• Mulder SJ, Mulder-Bos GC. Most probable origin of coeliac disease is low immune globulin A in the intestine caused by malfunction of Peyer's patches. Med. Hypotheses 66: 757-762 (2006).

• Muller C, Braag SA, Herlihy JD, Wasserfall CH, Chesrown SE, Nick HS, Atkinson MA, Flotte TR. Enhanced IgE allergic response to Aspergillus fumigatus in CFTR-/- mice. Lab. Invest. 86: 130-140 (2006). *

• Muller T, Hamm S, Bauer S. TLR9-mediated recognition of DNA. Handb. Exp. Pharmacol. 183: 51-70 (2008).

• Muller U, Stenzel W, Kohler G, Polte T, Blessing M, Mann A, Piehler D, Brombacher F, Alber G. A gene-dosage effect for interleukin-4 receptor alpha-chain expression has an impact on Th2-mediated allergic inflammation during bronchopulmonary mycosis. J. Infect. Dis. 198: 1714-1721 (2008). *

• Muller U, Stenzel W, Kohler G, Werner C, Polte T, Hansen G, Schutze N, Straubinger RK, Blessing M, McKenzie AN, Brombacher F, Alber G. IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans. J. Immunol. 179: 5367-5377 (2007). *

• Munthe-Kaas MC, Carlsen KL, Carlsen KH, Egeland T, Haland G, Devulapalli CS, Akselsen H, Undlien D. HLA DR-DQ haplotypes and the TNFA-308 polymorphism: associations with asthma and allergy. Allergy 62: 991-998 (2007).

• Munthe-Kaas MC, Hakon Carlsen K, Helms PJ, Gerritsen J, Whyte M, Feijen M, Skinningsrud B, Main M, Ng Man Kwong G, Lie BA, Lodrup Carlsen KC, Undlien DE. CTLA-4 polymorphisms in allergy and asthma and the TH1/TH2 paradigm. J. Allergy Clin. Immunol. 114: 280-287 (2004). *

• Murphy JM, Young IG. IL-3, IL-5, and GM-CSF signaling: crystal structure of the human beta-common receptor. Vitam. Horm. 74: 1-30 (2006).

• Murray CS, Simpson B, Kerry G, Woodcock A, Custovic A. Dietary intake in sensitized children with recurrent wheeze and healthy controls: a nested case-control study. Allergy 61: 438-442 (2006). *

• Musselli C, Daverio-Zanetti S, Zanetti M. Antigenized antibodies expressing Vb8.2 TCR peptides immunize against rat experimental allergic encephalomyelitis. J. Immune Based Ther. Vaccines 2: 9 (2004). *

• Muthian G, Raikwar HP, Johnson C, Rajasingh J, Kalgutkar A, Marnett LJ, Bright JJ. COX-2 inhibitors modulate IL-12 signaling through JAK-STAT pathway leading to Th1 response in experimental allergic encephalomyelitis. J. Clin. Immunol. 26: 73-85 (2006). *

• Muthian G, Raikwar HP, Rajasingh J, Bright JJ. 1,25 Dihydroxyvitamin-D3 modulates JAK-STAT pathway in IL-12/IFNgamma axis leading to Th1 response in experimental allergic encephalomyelitis. J. Neurosci. Res. 83: 1299-1309 (2006). *

• Mutschlechner S, Egger M, Briza P, Wallner M, Lackner P, Karle A, Vogt AB, Fischer GF, Bohle B, Ferreira F. Naturally processed T-cell-activating peptides of the major birch pollen allergen. J. Allergy Clin. Immunol. Feb 2 [Epub ahead of print] (2010). *

• Myers W, Newman M, Katz B, Gottlieb AB. Ability to develop rhus allergic contact dermatitis in a patient with psoriasis receiving etanercept. J. Am. Acad. Dermatol. 55: S127-S128 (2006).

• Myrelid P, Dufmats M, Lilja I, Grinn C, Lannerstad O, Sjodahl R. Atopic manifestations are more common in patients with Crohn disease than in the general population. Scand. J. Gastroenterol. 39: 731-736 (2004). *

• Nacak M, Erbagci Z, Aynacioglu AS. Human arylamine N-acetyltransferase 2 polymorphism and susceptibility to allergic contact dermatitis. Int. J. Dermatol. 45: 323-326 (2006). *

• Nacak M, Erbagci Z, Buyukafsar K, Yurtsever AS, Tiftik RN. Association of angiotensin-converting enzyme gene insertion/deletion polymorphism with allergic contact dermatitis. Basic Clin. Pharmacol. Toxicol. 101: 101-103 (2007).

• Nagano Y, Millar BC, Goldsmith CE, Walker JM, Elborn JS, Rendall J, Moore JE. Development of selective media for the isolation of yeasts and filamentous fungi from the sputum of adult patients with cystic fibrosis (CF). J. Cyst. Fibros. 7: 566-572 (2008).

• Nagarkatti M, Rieder SA, Vakharia D, Nagarkatti PS. Evaluation of apoptosis in immunotoxicity testing. Methods Mol. Biol. 598: 241-257 (2010). *

• Nagase K, Fukunaga K, Ohnishi K, Kusaka T, Matoba Y, Sawada K. Detection of specific IgE antibodies to nafamostat mesilate as an indication of possible adverse effects of leukocytapheresis using nafamostat mesilate as anticoagulant. Ther. Apher. 8: 45-51 (2004).

• Nagy A, Kozma GT, Bojszko A, Krikovszky D, Falus A, Szalai C. No association between asthma or allergy and the CCR5Delta 32 mutation. Arch. Dis. Child. 86: 426 (2002). *

• Naitoh I, Nakazawa T, Ohara H, Sano H, Ando T, Hayashi K, Tanaka H, Okumura F, Miyabe K, Yoshida M, Takahashi S, Joh T. Autoimmune pancreatitis associated with various extrapancreatic lesions during a long-term clinical course successfully treated with azathioprine and corticosteroid maintenance therapy. Intern. Med. 48: 2003-2007 (2009). *

• Najib U, Sheikh J. An update on acute and chronic urticaria for the primary care provider. Postgrad. Med. 121: 141-151 (2009).

• Nakae S, Iwakura Y, Suto H, Galli SJ. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J. Leukoc. Biol. 81: 1258-1268 (2007). *

• Nakae S, Komiyama Y, Nambu A, Sudo K, Iwase M, Homma I, Sekikawa K, Asano M, Iwakura Y. Antigen-specific T cell sensitization is impaired in IL-17-deficient mice, causing suppression of allergic cellular and humoral responses. Immunity 17: 375-387 (2002). *

• Nakae S, Lunderius C, Ho LH, Schafer B, Tsai M, Galli SJ. TNF can contribute to multiple features of ovalbumin-induced allergic inflammation of the airways in mice. J. Allergy Clin. Immunol. 119: 680-686 (2007). *

• Nakagome K, Okunishi K, Imamura M, Harada H, Matsumoto T, Tanaka R, Miyazaki J, Yamamoto K, Dohi M. IFN-gamma attenuates antigen-induced overall immune response in the airway as a Th1-type immune regulatory cytokine. J. Immunol. 183: 209-220 (2009).

• Nakamura M, Tsutsumi K, Ooka S, Sekine T, Koizuka I, Nishioka K, Kato T. Identification of beta-tubulin isoform V as an autoantigen in allergic rhinitis by a proteomic approach. Microbiol. Immunol. 48: 427-434 (2004).

• Nakamura Y, Miyata M, Ohba T, Ando T, Hatsushika K, Suenaga F, Shimokawa N, Ohnuma Y, Katoh R, Ogawa H, Nakao A. Cigarette smoke extract induces thymic stromal lymphopoietin expression, leading to T(H)2-type immune responses and airway inflammation. J. Allergy Clin. Immunol. 122: 1208-1214 (2008).

• Nakanishi K, Yoshimoto T, Tsutsui H, Okamura H. Interleukin-18 regulates both Th1 and Th2 responses. Annu. Rev. Immunol. 19: 423-474 (2001). *

• Nakashima K, Hirota T, Obara K, Shimizu M, Doi S, Fujita K, Shirakawa T, Enomoto T, Yoshihara S, Ebisawa M, Matsumoto K, Saito H, Suzuki Y, Nakamura Y, Tamari M. A functional polymorphism in MMP-9 is associated with childhood atopic asthma. Biochem. Biophys. Res. Commun. 344: 300-307 (2006). *

• Nakashima K, Hirota T, Obara K, Shimizu M, Jodo A, Kameda M, Doi S, Fujita K, Shirakawa T, Enomoto T, Kishi F, Yoshihara S, Matsumoto K, Saito H, Suzuki Y, Nakamura Y, Tamari M. An association study of asthma and related phenotypes with polymorphisms in negative regulator molecules of the TLR signaling pathway. J. Hum. Genet. 51: 284-291 (2006). *

• Nakashima K, Hirota T, Suzuki Y, Akahoshi M, Shimizu M, Jodo A, Doi S, Fujita K, Ebisawa M, Yoshihara S, Enomoto T, Shirakawa T, Kishi F, Nakamura Y, Tamari M. Association of the RIP2 gene with childhood atopic asthma. Allergol. Int. 55: 77-83 (2006). *

• Nakayama EE, Wasi C, Ajisawa A, Iwamoto A, Shioda T. A new polymorphism in the promoter region of the human interleukin-16 (IL-16) gene. Genes Immun. 1: 293-294 (2000). *

• Nakazato J, Kishida M, Kuroiwa R, Fujiwara J, Shimoda M, Shinomiya N. Serum levels of Th2 chemokines, CCL17, CCL22, and CCL27, were the important markers of severity in infantile atopic dermatitis. Pediatr. Allergy Immunol. 19: 605-613 (2008). *

• Namazi MR. The beneficial and detrimental effects of linoleic acid on autoimmune disorders. Autoimmunity 37: 73-75 (2004).

• Namkung JH, Lee JE, Kim E, Kim S, Kim S, Shin ES, Cho EY, Yang JM. Association of single nucleotide polymorphisms in the IL-12 (IL-12A and B) and IL-12 receptor (IL-12Rbeta1 and beta2) genes and gene-gene interactions with atopic dermatitis in Koreans. J. Dermatol. Sci. Jan 6 [Epub ahead of print] (2010).

• Namura K, Hasegawa G, Egawa M, Matsumoto T, Kobayashi R, Yano T, Katoh N, Kishimoto S, Ohta M, Obayashi H, Ose H, Fukui M, Nakamura N, Yoshikawa T. Relationship of serum brain-derived neurotrophic factor level with other markers of disease severity in patients with atopic dermatitis. Clin. Immunol. 122: 181-186 (2007). *

• Natarajan C, Bright JJ. Curcumin inhibits experimental allergic encephalomyelitis by blocking IL-12 signaling through Janus kinase-STAT pathway in T lymphocytes. J. Immunol. 168: 6506-6513 (2002). *

• Natarajan C, Bright JJ. Peroxisome proliferator-activated receptor-gamma agonists inhibit experimental allergic encephalomyelitis by blocking IL-12 production, IL-12 signaling and Th1 differentiation. Genes Immun. 3: 59-70 (2002). *

• Neff GW, Ruiz P, Madariaga JR, Nishida S, Montalbano M, Meyer D, Levi DM, Tzakis AG, O'Brien CB. Sirolimus-associated hepatotoxicity in liver transplantation. Ann. Pharmacother. 38: 1593-1596 (2004).

• Negoro T, Orihara K, Irahara T, Nishiyama H, Hagiwara K, Nishida R, Takagi H, Satoh K, Yamamoto Y, Shimizu S, Hagiwara T, Ishii M, Tanioka T, Nakano Y, Takeda K, Yoshimura I, Iikura Y, Tobe T. Influence of SNPs in cytokine-related genes on the severity of food allergy and atopic eczema in children. Pediatr. Allergy Immunol. 17: 583-590 (2006).

• Negrao-Correa D, Teixeira MM. The mutual influence of nematode infection and allergy. Chem. Immunol. Allergy 90: 14-28 (2006).

• Neis MM, Peters B, Dreuw A, Wenzel J, Bieber T, Mauch C, Krieg T, Stanzel S, Heinrich PC, Merk HF, Bosio A, Baron JM, Hermanns HM. Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis. J. Allergy Clin. Immunol. 118: 930-937 (2006). *

• Neuber K, Mahnss B, Hubner C, Gergely H, Weichenthal M. Autoantibodies against CD28 are associated with atopic diseases. Clin. Exp. Immunol. 146: 262-269 (2006). *

• Neurath MF, Wanitschke R, Peters M, Krummenauer F, Meyer zum Buschenfelde KH, Schlaak JF. Randomised trial of mycophenolate mofetil versus azathioprine for treatment of chronic active Crohn's disease. Gut 44: 625-628 (1999). *

• Neves JS, Weller PF. Functional extracellular eosinophil granules: novel implications in eosinophil immunobiology. Curr. Opin. Immunol. 21: 694-699 (2009).

• Neveu WA, Allard JB, Dienz O, Wargo MJ, Ciliberto G, Whittaker LA, Rincon M. IL-6 is required for airway mucus production induced by inhaled fungal allergens. J. Immunol. 183: 1732-1738 (2009).

• Ng MT, van 't Hof R, Crockett JC, Hope ME, Berry S, Thomson J, McLean MH, McColl KE, El-Omar EM, Hold GL. Increase in NF-kappaB binding affinity of the C allelic variant of the Toll-like receptor 9 -1237T/C polymorphism is associated with Helicobacter pylori induced gastric disease. Infect. Immun. Dec 28 [Epub ahead of print] (2009). *

• Ng N, Lam D, Paulus P, Batzer G, Horner AA. House dust extracts have both T(H)2 adjuvant and tolerogenic activities. J. Allergy Clin. Immunol. 117: 1074-1081 (2006). *

• Ngo P, Furuta G, Burks W. The pathobiology of eosinophilic gastroenteritis of childhood: is it really the eosinophil, allergic mediated, or something else? Curr. Gastroenterol. Rep. 6: 436-440 (2004).

• Nichols FC, Housley WJ, O'Conor CA, Manning T, Wu S, Clark RB. Unique lipids from a common human bacterium represent a new class of Toll-like receptor 2 ligands capable of enhancing autoimmunity. Am. J. Pathol. 175: 2430-2438 (2009). *

• Nicolas JM, Espie P, Molimard M. Gender and interindividual variability in pharmacokinetics. Drug Metab. Rev. 41: 408-421 (2009).

• Nicoletti F, Creange A, Orlikowski D, Bolgert F, Mangano K, Metz C, Di Marco R, Al Abed Y. Macrophage migration inhibitory factor (MIF) seems crucially involved in Guillain-Barre syndrome and experimental allergic neuritis. J. Neuroimmunol. 168: 168-174 (2005).

• Nicolson KS, Wraith DC. Natural and induced regulatory T cells: targets for immunotherapy of autoimmune disease and allergy. Inflamm. Allergy Drug Targets 5: 141-148 (2006).

• Nielsen RG, Husby S. Eosinophilic oesophagitis: epidemiology, clinical aspects, and association to allergy. J. Pediatr. Gastroenterol. Nutr. 45: 281-289 (2007). *

• Nieminen K, Valovirta E, Savolainen J. Clinical outcome and IL-17, IL-23, IL-27 and FOXP3 expression in peripheral blood mononuclear cells of pollen-allergic children during sublingual immunotherapy. Pediatr. Allergy Immunol. Jun 29 [Epub ahead of print] (2009). *

• Nigo YI, Yamashita M, Hirahara K, Shinnakasu R, Inami M, Kimura M, Hasegawa A, Kohno Y, Nakayama T. Regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. Proc. Natl. Acad. Sci. U.S.A. 103: 2286-2291 (2006). *

• Nilsson L, Kivling A, Jalmelid M, Magnusson KF, Faresjo M. Combinations of common chronic paediatric diseases deviate the immune response in diverging directions. Clin. Exp. Immunol. 146: 433-442 (2006). *

• Nitto T, Dyer KD, Mejia RA, Bystrom J, Wynn TA, Rosenberg HF. Characterization of the divergent eosinophil ribonuclease, mEar 6, and its expression in response to Schistosoma mansoni infection in vivo. Genes Immun. 5: 668-674 (2004). *

• Niu N, Laufer T, Homer RJ, Cohn L. Cutting edge: limiting MHC class II expression to dendritic cells alters the ability to develop Th2-dependent allergic airway inflammation. J. Immunol. 183: 1523-1527 (2009).

• No authors listed. In this issue. Eur. J. Immunol. 38: 1773-1774 (2008). *

• No authors listed. In this issue. Eur. J. Immunol. 39: 628-629 (2009). *

• No authors listed. In this issue. Eur. J. Immunol. 39: 3274-3275 (2009). *

• No authors listed. In this issue. Eur. J. Immunol. 39: 1690-1691 (2009).

• No authors listed. The specific features of TNF-alpha gene polymorphism in asthmatic patients and their relatives. Probl. Tuberk. Bolezn. Legk. 8: 51-56 (2009).

• No authors listed. Beclometasone Oral - DOR BioPharma: Beclomethasone Oral - DOR BioPharma. Drugs R. D. 9: 271-276 (2008).

• Noakes PS, Hale J, Thomas R, Lane C, Devadason SG, Prescott SL. Maternal smoking is associated with impaired neonatal Toll-like receptor (TLR) mediated immune responses. Eur. Respir. J. 28: 721-729 (2006).

• Noble A. Do we have memory of danger as well as antigen? Trends Immunol. 30: 150-156 (2009). *

• Noble A, Giorgini A, Leggat JA. Cytokine-induced IL-10-secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage. Blood 107: 4475-4483 (2006). *

• Noguchi E, Yokouchi Y, Shibasaki M, Kamioka M, Yamakawa-Kobayashi K, Matsui A, Arinami T. Identification of missense mutation in the IL12B gene: lack of association between IL12B polymorphisms and asthma and allergic rhinitis in the Japanese population. Genes Immun. 2: 401-403 (2001). *

• Nonaka M, Fukumoto A, Ogihara N, Sakanushi A, Pawankar R, Yagi T. Synergistic induction of thymic stromal lymphopoietin by tumor necrosis factor alpha and Th2 cytokine in nasal polyp fibroblasts. Am. J. Rhinol. Allergy. 24: 14-18 (2010).

• Noone PG, Knowles MR. 'CFTR-opathies': disease phenotypes associated with cystic fibrosis transmembrane regulator gene mutations. Respir. Res. 2: 328-332 (2001). *

• Noubade R, Del Rio R, McElvany B, Zachary JF, Millward JM, Wagner DD, Offner H, Blankenhorn EP, Teuscher C. Von-Willebrand factor influences blood brain barrier permeability and brain inflammation in experimental allergic encephalomyelitis. Am. J. Pathol. 173: 892-900 (2008). *

• Noubade R, Saligrama N, Spach K, Del Rio R, Blankenhorn EP, Kantidakis T, Milligan G, Rincon M, Teuscher C. Autoimmune disease-associated histamine receptor H1 alleles exhibit differential protein trafficking and cell surface expression. J. Immunol. 180: 7471-7479 (2008). *

• Nouri-Aria KT, Durham SR. Regulatory T cells and allergic disease. Inflamm. Allergy Drug Targets 7: 237-252 (2008).

• Novembre E, Cianferoni A, Mori F, Barni S, Calogero C, Bernardini R, Di Grande L, Pucci N, Azzari C, Vierucci A. Urticaria and urticaria related skin condition/disease in children. Eur. Ann. Allergy Clin. Immunol. 40: 5-13 (2008).

• Novikova AV, Shcherbakov IT, Ol'shanskii IaO, Iurkov MM, Levitan MKh. Features of inflammation of the mucosa of the large intestine in nonspecific ulcerative colitis and Crohn's disease. Arkh. Patol. 44: 31-39 (1982).

• Noya O, Losada S, Toledo M, Alarcon de Noya B. The multiple antigen blot assay: a simple, versatile and multipurpose immunoenzymatic technique. Methods Mol. Biol. 536: 237-251 (2009).

• Nozad CH, Michael LM, Lew DB, Michael CF. Non-allergic rhinitis: a case report and review. Clin. Mol. Allergy 8: 1 (2010). *

• Nwaru BI, Erkkola M, Ahonen S, Kaila M, Haapala AM, Kronberg-Kippila C, Salmelin R, Veijola R, Ilonen J, Simell O, Knip M, Virtanen SM. Age at the introduction of solid foods during the first year and allergic sensitization at age 5 years. Pediatrics Dec 7 [Epub ahead of print] (2009). *

• O'Connor PW, Li D, Freedman MS, Bar-Or A, Rice GP, Confavreux C, Paty DW, Stewart JA, Scheyer R; Teriflunomide Multiple Sclerosis Trial Group; University of British Columbia MS/MRI Research Group. A phase II study of the safety and efficacy of teriflunomide in multiple sclerosis with relapses. Neurology 66: 894-900 (2006).

• O'Connor RA, Taams LS, Anderton SM. Translational mini-review series on Th17 cells: CD4(+) T helper cells: functional plasticity and differential sensitivity to regulatory T cell-mediated regulation. Clin. Exp. Immunol. 159: 137-147 (2010). *

• O'Connor TM, O'Connell J, O'Brien DI, Goode T, Bredin CP, Shanahan F. The role of substance P in inflammatory disease. J. Cell. Physiol. 201: 167-180 (2004). *

• O'Garra A, Steinman L, Gijbels K. CD4+ T-cell subsets in autoimmunity. Curr. Opin. Immunol. 9: 872-883 (1997).

• O'Hehir RE, Lake RA, Schall TJ, Yssel H, Panagiotopoulou E, Lamb JR. Regulation of cytokine and chemokine transcription in a human TH2 type T-cell clone during the induction phase of anergy. Clin. Exp. Allergy 26: 20-27 (1996).

• O'Malley JT, Sehra S, Thieu VT, Yu Q, Chang HC, Stritesky GL, Nguyen ET, Mathur AN, Levy DE, Kaplan MH. Signal transducer and activator of transcription 4 limits the development of adaptive regulatory T cells. Immunology 127: 587-595 (2009). *

• O'Neill EJ, Sundstedt A, Mazza G, Nicolson KS, Ponsford M, Saurer L, Streeter H, Anderton S, Wraith DC. Natural and induced regulatory T cells. Ann. N. Y. Acad. Sci. 1029: 180-192 (2004). *

• Oboki K, Ohno T, Saito H, Nakae S. Th17 and allergy. Allergol. Int. 57: 121-134 (2008). *

• Offit PA, Hackett CJ. Addressing parents' concerns: do vaccines cause allergic or autoimmune diseases? Pediatrics 111: 653-659 (2003). *

• Ogawa T, Miura S, Tsuzuki Y, Ogino T, Teramoto K, Inamura T, Watanabe C, Hokari R, Nagata H, Ishii H. Chronic allergy to dietary ovalbumin induces lymphocyte migration to rat small intestinal mucosa that is inhibited by MAdCAM-1. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G702-G710 (2004). *

• Ogawa Y, Duru EA, Ameredes BT. Role of IL-10 in the resolution of airway inflammation. Curr. Mol. Med. 8: 437-445 (2008).

• Ogra PL, Welliver RC. Effects of early environment on mucosal immunologic homeostasis, subsequent immune responses and disease outcome. Nestle Nutr. Workshop Ser. Pediatr. Program 61: 145-181 (2008).

• Oh HE, Chetty R. Eosinophilic gastroenteritis: a review. J. Gastroenterol. 43: 741-750 (2008). *

• Oh JW, Seroogy CM, Meyer EH, Akbari O, Berry G, Fathman CG, Dekruyff RH, Umetsu DT. CD4 T-helper cells engineered to produce IL-10 prevent allergen-induced airway hyperreactivity and inflammation. J. Allergy Clin. Immunol. 110: 460-468 (2002). *

• Oh SH, Park SM, Lee YH, Cha JY, Lee JY, Shin EK, Park JS, Park BL, Shin HD, Park CS. Association of peroxisome proliferator-activated receptor-gamma gene polymorphisms with the development of asthma. Respir. Med. 103: 1020-1024 (2009).

• Ohmori K, Hasegawa K, Tamura T, Miyake K, Matsubara M, Masaki S, Karasawa A, Urayama N, Horikoshi K, Kajita J, Hasegawa M, Taniguchi K, Komada T, Kawamoto Y. Properties of olopatadine hydrochloride, a new antiallergic/antihistaminic drug. Arzneimittelforschung 54: 809-829 (2004).

• Ohta K. Present state and future view of allergic disease - especially focusing on asthma. Nippon Rinsho 67: 2033-2038 (2009).

• Ohtsu H. Progress in allergy signal research on mast cells: the role of histamine in immunological and cardiovascular disease and the transporting system of histamine in the cell. J. Pharmacol. Sci. 106: 347-353 (2008). *

• Oien T, Storro O, Johnsen R. Do early intake of fish and fish oil protect against eczema and doctor-diagnosed asthma at 2 years of age? A cohort study. J. Epidemiol. Community Health Aug 6 [Epub ahead of print] (2009).

• Ojuawo A, Milla PJ, Lindley KJ. Non infective colitis in infancy: evidence in favour of minor immunodeficiency in its pathogenesis. East Afr. Med. J. 74: 233-236 (1997).

• Ojuawo A, St Louis D, Lindley KJ, Milla PJ. Non-infective colitis in infancy: evidence in favour of minor immunodeficiency in its pathogenesis. Arch. Dis. Child. 76: 345-348 (1997). *

• Okamoto M, Matsuda H, Joetham A, Lucas JJ, Domenico J, Yasutomo K, Takeda K, Gelfand EW. Jagged1 on dendritic cells and Notch on CD4+ T cells initiate lung allergic responsiveness by inducing IL-4 production. J. Immunol. 183: 2995-3003 (2009).

• Okamoto M, Van Stry M, Chung L, Koyanagi M, Sun X, Suzuki Y, Ohara O, Kitamura H, Hijikata A, Kubo M, Bix M. Mina, an Il4 repressor, controls T helper type 2 bias. Nat. Immunol. 10: 872-879 (2009). *

• Oki S, Miyake S. Invariant natural killer T (iNKT) cells in asthma: a novel insight into the pathogenesis of asthma and the therapeutic implication of glycolipid ligands for allergic diseases. Allergol. Int. 56: 7-14 (2007).

• Okpara N, Aswad B, Baffy G. Eosinophilic colitis. World J. Gastroenterol. 15: 2975-2979 (2009). *

• Okunishi K, Dohi M, Fujio K, Nakagome K, Tabata Y, Okasora T, Seki M, Shibuya M, Imamura M, Harada H, Tanaka R, Yamamoto K. Hepatocyte growth factor significantly suppresses collagen-induced arthritis in mice. J. Immunol. 179: 5504-5513 (2007). *

• Olive C. T cell receptor usage in autoimmune disease. Immunol. Cell Biol. 73: 297-307 (1995).

• Oliveira RR, Gollob KJ, Figueiredo JP, Alcantara LM, Cardoso LS, Aquino CS, Campos RA, Almeida MC, Carvalho EM, Araujo MI. Schistosoma mansoni infection alters co-stimulatory molecule expression and cell activation in asthma. Microbes Infect. 11: 223-229 (2009). *

• Olsen SF, Osterdal ML, Salvig JD, Mortensen LM, Rytter D, Secher NJ, Henriksen TB. Fish oil intake compared with olive oil intake in late pregnancy and asthma in the offspring: 16 y of registry-based follow-up from a randomized controlled trial. Am. J. Clin. Nutr. 88: 167-175 (2008). *

• Omiya R, Tsushima F, Narazaki H, Sakoda Y, Kuramasu A, Kim Y, Xu H, Tamura H, Zhu G, Chen L, Tamada K. Leucocyte-associated immunoglobulin-like receptor-1 is an inhibitory regulator of contact hypersensitivity. Immunology 128: 543-555 (2009). *

• Ono SJ. Molecular genetics of allergic diseases. Annu. Rev. Immunol. 18: 347-366 (2000). *

• Oreshkova T, Wang H, Seier AM, Sindrilaru A, Varga G, Grabbe S, Scharffetter-Kochanek K, Peters T. Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice. Immunology 128: 271-286 (2009). *

• Orozco CV, Velasquez LH, Mendez NH, Augusto B, Salazar T. Hyper IgE syndrome. Opportune diagnosis and management. Rev. Alerg. Mex. 55: 38-45 (2008).

• Ortega-Deballon P, Carabias-Hernandez A, Martin-Blazquez A, Garaulet P, Benoit L, Kretz B, Limones-Esteban M, Favre JP. Anisakiasis: an infestation to be known by surgeons. Ann. Chir. 130: 407-410 (2005).

• Osada Y, Kanazawa T. Parasitic helminths: new weapons against immunological disorders. J. Biomed. Biotechnol. 2010: 743758 (2010). *

• Osada Y, Shimizu S, Kumagai T, Yamada S, Kanazawa T. Schistosoma mansoni infection reduces severity of collagen-induced arthritis via down-regulation of pro-inflammatory mediators. Int. J. Parasitol. 39: 457-464 (2009).

• Oshima M, Deitiker P, Atassi M. Targeting the antigen-binding site of HLA-restricting alleles in treatment of autoimmune disease. Crit. Rev. Immunol. 27: 271-288 (2007).

• Oshima M, Ohtani M, Deitiker PR, Glenn Smith R, Mosier DR, Zouhair Atassi M. Suppression by mAbs against DQB1 peptides of in vitro proliferation of AChR-specific T cells from myasthenia gravis patients. Autoimmunity 38: 161-169 (2005).

• Oskeritzian CA, Alvarez SE, Hait NC, Price MM, Milstien S, Spiegel S. Distinct roles of sphingosine kinases 1 and 2 in human mast cell functions. Blood 111: 4193-4200 (2008). *

• Ostergaard PA, Eriksen J. Association between HLA-A1,B8 in children with extrinsic asthma and IgA deficiency. Eur. J. Pediatr. 131: 263-270 (1979).

• Ostroukhova M, Qi Z, Oriss TB, Dixon-McCarthy B, Ray P, Ray A. Treg-mediated immunosuppression involves activation of the Notch-HES1 axis by membrane-bound TGF-beta. J. Clin. Invest. 116: 996-1004 (2006). *

• Ostroukhova M, Ray A. CD25+ T cells and regulation of allergen-induced responses. Curr. Allergy Asthma Rep. 5: 35-41 (2005).

• Ou-Yang HF, Hu XB, Ti XY, Shi JR, Li SJ, Qi HW, Wu CG. Suppression of allergic airway inflammation in a mouse model by Der p2 recombined BCG. Immunology 128: e343-e352 (2009). *

• Ouaked N, Mantel PY, Bassin C, Burgler S, Siegmund K, Akdis CA, Schmidt-Weber CB. Regulation of the Foxp3 gene by the Th1 cytokines: the role of IL-27-induced STAT1. J. Immunol. 182: 1041-1049 (2009).

• Oxelius VA. Immunoglobulin constant heavy G subclass chain genes in asthma and allergy. Immunol. Res. 40: 179-191 (2008). *

• Oyoshi MK, Elkhal A, Kumar L, Scott JE, Koduru S, He R, Leung DY, Howell MD, Oettgen HC, Murphy GF, Geha RS. Vaccinia virus inoculation in sites of allergic skin inflammation elicits a vigorous cutaneous IL-17 response. Proc. Natl. Acad. Sci. U.S.A. 106: 14954-14959 (2009). *

• Ozaki S. ANCA-associated vasculitis: diagnostic and therapeutic strategy. Allergol. Int. 56: 87-96 (2007). *

• Ozcan C, Tamer L, Ates NA, Gorur K. The glutathione-S-transferase gene polymorphisms (Gstt1, Gstm1, and Gstp1) in patients with non-allergic nasal polyposis. Eur. Arch. Otorhinolaryngol. Aug 23 [Epub ahead of print] (2009).

• Ozseker F, Buyukozturk S, Gelincik A, Depboylu B, Genc S, Giris M, Eroglu H, Erden S, Colakoglu B, Dal M, Akkor A. Neurotrophins: are they meaningful in chronic spontaneous urticaria? Asian Pac. J. Allergy Immunol. 26: 83-88 (2008).

• Pachkoria K, Lucena MI, Molokhia M, Cueto R, Carballo AS, Carvajal A, Andrade RJ. Genetic and molecular factors in drug-induced liver injury: a review. Curr. Drug Saf. 2: 97-112 (2007). *

• Padhye U. Excess dietary iron is the root cause for increase in childhood autism and allergies. Med. Hypotheses 61: 220-222 (2003). *

• Page K, Ledford JR, Zhou P, Wills-Karp M. A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice. J. Immunol. 183: 3400-3408 (2009).

• Page NS, Jones G, Stewart GJ. Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis. Int. Arch. Allergy Immunol. 141: 331-336 (2006).

• Palakal M, Bright J, Sebastian T, Hartanto S. A comparative study of cells in inflammation, EAE and MS using biomedical literature data mining. J. Biomed. Sci. 14: 67-85 (2007). *

• Palomares O, Yaman G, Azkur AK, Akkoc T, Akdis M, Akdis CA. Role of T regulatory cells in immune regulation of allergic diseases. Eur. J. Immunol. Feb 10 [Epub ahead of print] (2010). *

• Paltiel M, Gober LM, Deng A, Mikdashi J, Alexeeva I, Saini SS, Gaspari AA. Immediate type I hypersensitivity response implicated in worsening injection site reactions to adalimumab. Arch. Dermatol. 144: 1190-1194 (2008). *

• Pampuch A, Kowal K, Bodzenta-Lukaszyk A, Castelnuovo AD, Chyczewski L, Donati MB, Iacoviello L. The -675 4G/5G plasminogen activator inhibitor-1 promoter polymorphism in house dust mite-sensitive allergic asthma patients. Allergy 61: 234-238 (2006). *

• Pan SM, Dehler S, Ciurea A, Ziswiler HR, Gabay C, Finckh A; Swiss Clinical Quality Management Physicians. Comparison of drug retention rates and causes of drug discontinuation between anti-tumor necrosis factor agents in rheumatoid arthritis. Arthritis Rheum. 61: 560-568 (2009). *

• Pantelidis P, Jones MG, Welsh KI, Taylor AN, du Bois RM. Identification of four novel interleukin-13 gene polymorphisms. Genes Immun. 1: 341-345 (2000). *

• Panter G, Kuznik A, Jerala R. Therapeutic applications of nucleic acids as ligands for Toll-like receptors. Curr. Opin. Mol. Ther. 11: 133-145 (2009).

• Papadakis KA, Shaye OA, Vasiliauskas EA, Ippoliti A, Dubinsky MC, Loane J, Paavola J, Lee SK, Price J, Targan SR, Abreu MT. Safety and efficacy of adalimumab (D2E7) in Crohn's disease patients with an attenuated response to infliximab. Am. J. Gastroenterol. 100: 75-79 (2005). *

• Pappu BP, Angkasekwinai P, Dong C. Regulatory mechanisms of helper T cell differentiation: new lessons learned from interleukin 17 family cytokines. Pharmacol. Ther. 117: 374-384 (2008). *

• Pappu BP, Dong C. Measurement of interleukin-17. Curr. Protoc. Immunol. Chapter 6: Unit 6.25 (2007).

• Park BL, Kim LH, Choi YH, Cheong HS, Park HS, Hong SJ, Choi BW, Lee JH, Uh ST, Park CS, Shin HD. Association analysis of monocyte chemotactic protein-3 (MCP3) polymorphisms with asthmatic phenotypes. J. Biochem. Mol. Biol. 38: 77-81 (2005). *

• Park HH, Lee S, Son HY, Park SB, Kim MS, Choi EJ, Singh TS, Ha JH, Lee MG, Kim JE, Hyun MC, Kwon TK, Kim YH, Kim SH. Flavonoids inhibit histamine release and expression of proinflammatory cytokines in mast cells. Arch. Pharm. Res. 31: 1303-1311 (2008). *

• Park HJ, Ye YM, Hur GY, Kim SH, Park HS. Association between a TGFbeta1 promoter polymorphism and the phenotype of aspirin-intolerant chronic urticaria in a Korean population. J. Clin. Pharm. Ther. 33: 691-697 (2008). *

• Park MA, Li JT, Hagan JB, Maddox DE, Abraham RS. Common variable immunodeficiency: a new look at an old disease. Lancet 372: 489-502 (2008). *

• Park SJ, Lee KS, Kim SR, Min KH, Choe YH, Moon H, Chae HJ, Yoo WH, Lee YC. Peroxisome proliferator-activated receptor gamma agonist down-regulates IL-17 expression in a murine model of allergic airway inflammation. J. Immunol. 183: 3259-3267 (2009).

• Park YR, Choi SC, Lee ST, Kim KS, Chae SC, Chung HT. The association of eotaxin-2 and eotaxin-3 gene polymorphisms in a Korean population with ulcerative colitis. Exp. Mol. Med. 37: 553-558 (2005). *

• Parkinson T. The future of Toll-like receptor therapeutics. Curr. Opin. Mol. Ther. 10: 21-31 (2008).

• Parvaneh Tafreshi A. Nerve growth factor prevents demyelination, cell death and progression of the disease in experimental allergic encephalomyelitis. Iran. J. Allergy Asthma Immunol. 5: 177-181 (2006).

• Parvaneh Tafreshi A, Mostafavi H, Zeynali B. Induction of experimental allergic encephalomyelitis in C57/BL6 mice: an animal model for multiple sclerosis. Iran. J. Allergy Asthma Immunol. 4: 113-117 (2005).

• Pasquier B, Launay P, Kanamaru Y, Moura IC, Pfirsch S, Ruffie C, Henin D, Benhamou M, Pretolani M, Blank U, Monteiro RC. Identification of FcalphaRI as an inhibitory receptor that controls inflammation: dual role of FcRgamma ITAM. Immunity 22: 31-42 (2005). *

• Pastore S, Mascia F, Mariotti F, Dattilo C, Girolomoni G. Chemokine networks in inflammatory skin diseases. Eur. J. Dermatol. 14: 203-208 (2004).

• Patel M, Xu D, Kewin P, Choo-Kang B, McSharry C, Thomson NC, Liew FY. Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. Eur. J. Immunol. 35: 3581-3590 (2005). *

• Patel MJ, Ulrich C, Forschner T. Genetically determined susceptibility to COX-2 inhibitors - a report of exaggerated responders to diclofenac 3% gel in the treatment of actinic keratoses. Br. J. Dermatol. 156 Suppl. 3: 57-61 (2007).

• Patel P, Barone F, Nunes C, Boursier L, Odell E, Escudier M, Challacombe S, Brostoff J, Spencer J, Sanderson J. Subepithelial dendritic B cells in orofacial granulomatosis. Inflamm. Bowel Dis. Nov 18 [Epub ahead of print] (2009).

• Patriarca G, Pogna N, Cammarota G, Schiavino D, Lombardo C, Pollastrini E, De Pasquale T, Buonomo A, Nocente F, Gazza L, Pietrini D, Miele L, Nucera E, Gasbarrini G. An attempt of specific desensitising treatment with gliadin in celiac disease. Int. J. Immunopathol. Pharmacol. 18: 709-714 (2005).

• Patterson DS, Allen WM. Chronic mycobacterial enteritis in ruminants as a model of Crohn's disease. Proc. R. Soc. Med. 65: 998-1001 (1972). *

• Paus R, Theoharides TC, Arck PC. Neuroimmunoendocrine circuitry of the 'brain-skin connection'. Trends Immunol. 27: 32-39 (2006). *

• Pawate S, Sriram S. Isolated longitudinal myelitis: a report of six cases. Spinal Cord 47: 257-261 (2009).

• Pawlik A, Juzyszyn Z, Gawronska-Szklarz B. N-acetyltransferase 2 (NAT2) polymorphism in patients with atopic asthma. Arch. Med. Res. 40: 264-267 (2009).

• Pawlik A, Kaminski M, Kusnierczyk P, Kurzawski M, Dziedziejko V, Adamska M, Safranow K, Gawronska-Szklarz B. Interleukin-18 promoter polymorphism in patients with atopic asthma. Tissue Antigens 70: 314-318 (2007). *

• Pedersen AE, Gad M, Kristensen NN, Haase C, Nielsen CH, Claesson MH. Tolerogenic dendritic cells pulsed with enterobacterial extract suppress development of colitis in the severe combined immunodeficiency transfer model. Immunology 121: 526-532 (2007). *

• Pedersen MB, Skov L, Menne T, Johansen JD, Olsen J. Gene expression time course in the human skin during elicitation of allergic contact dermatitis. J. Invest. Dermatol. 127: 2585-2595 (2007). *

• Pedotti R, Farinotti M, Falcone C, Borgonovo L, Confalonieri P, Campanella A, Mantegazza R, Pastorello E, Filippini G. Allergy and multiple sclerosis: a population-based case-control study. Mult. Scler. 15: 899-906 (2009). *

• Pena AS, Crusius JB. Food allergy, coeliac disease and chronic inflammatory bowel disease in man. Vet. Q. 20 Suppl. 3: S49-S52 (1998).

• Penders J, Stobberingh EE, van den Brandt PA, Thijs C. The role of the intestinal microbiota in the development of atopic disorders. Allergy 62: 1223-1236 (2007). *

• Pene J, Chevalier S, Preisser L, Venereau E, Guilleux MH, Ghannam S, Moles JP, Danger Y, Ravon E, Lesaux S, Yssel H, Gascan H. Chronically inflamed human tissues are infiltrated by highly differentiated Th17 lymphocytes. J. Immunol. 180: 7423-7430 (2008). *

• Peng J, Yang XO, Chang SH, Yang J, Dong C. IL-23 signaling enhances Th2 polarization and regulates allergic airway inflammation. Cell Res. Nov 24 [Epub ahead of print] (2009).

• Penido C, Costa MF, Souza MC, Costa KA, Candea AL, Benjamim CF, Henriques MG. Involvement of CC chemokines in gammadelta T lymphocyte trafficking during allergic inflammation: the role of CCL2/CCR2 pathway. Int. Immunol. 20: 129-139 (2008). *

• Peppercorn MA. Sulfasalazine. Pharmacology, clinical use, toxicity, and related new drug development. Ann. Intern. Med. 101: 377-386 (1984).

• Pergola C, Dodt G, Rossi A, Neunhoeffer E, Lawrenz B, Northoff H, Samuelsson B, Radmark O, Sautebin L, Werz O. ERK-mediated regulation of leukotriene biosynthesis by androgens: a molecular basis for gender differences in inflammation and asthma. Proc. Natl. Acad. Sci. U.S.A. 105: 19881-19886 (2008). *

• Perrier C, Thierry AC, Mercenier A, Corthesy B. Allergen-specific antibody and cytokine responses, mast cell reactivity and intestinal permeability upon oral challenge of sensitized and tolerized mice. Clin. Exp. Allergy Aug 18 [Epub ahead of print] (2009). *

• Pesci A, Pavone L, Buzio C, Manganelli P. Respiratory system involvement in ANCA-associated systemic vasculitides. Sarcoidosis Vasc. Diffuse Lung Dis. 22 Suppl. 1: S40-S48 (2005).

• Pescini Gobert R, van den Eijnden M, Szyndralewiez C, Jorand-Lebrun C, Swinnen D, Chen L, Gillieron C, Pixley F, Juillard P, Gerber P, Johnson-Leger C, Halazy S, Camps M, Bombrun A, Shipp M, Vitte PA, Ardissone V, et al. GLEPP1/protein tyrosine phosphatase-phi inhibitors block chemotaxis in vitro and in vivo and improve murine ulcerative colitis. J. Biol. Chem. 284: 11385-11395 (2009). *

• Pesonen M, Kallio MJ, Siimes MA, Ranki A. Retinol concentrations after birth are inversely associated with atopic manifestations in children and young adults. Clin. Exp. Allergy 37: 54-61 (2007). *

• Peters M, Dudziak K, Stiehm M, Bufe A. T-cell polarization depends on concentration of the danger signal used to activate dendritic cells. Immunol. Cell Biol. Feb 2 [Epub ahead of print] (2010). *

• Peters T, Sindrilaru A, Wang H, Oreshkova T, Renkl AC, Kess D, Scharffetter-Kochanek K. CD18 in monogenic and polygenic inflammatory processes of the skin. J. Investig. Dermatol. Symp. Proc. 11: 7-15 (2006).

• Petithory JC. New data on anisakiasis. Bull. Acad. Natl. Med. 191: 53-65 (2007).

• Petrosino S, Cristino L, Karsak M, Gaffal E, Ueda N, Tuting T, Bisogno T, De Filippis D, D'Amico A, Saturnino C, Orlando P, Zimmer A, Iuvone T, Di Marzo V. Protective role of palmitoylethanolamide in contact allergic dermatitis. Allergy Nov 11 [Epub ahead of print] (2009). *

• Philpott H, Kette F, Hissaria P, Gillis D, Smith W. Chronic urticaria: the autoimmune paradigm. Intern. Med. J. 38: 852-857 (2008). *

• Phipps S, Hansbro N, Lam CE, Foo SY, Matthaei KI, Foster PS. Allergic sensitization is enhanced in early life through Toll-like receptor 7 activation. Clin. Exp. Allergy Sep 3 [Epub ahead of print] (2009). *

• Phipps S, Lam CE, Foster PS, Matthaei KI. The contribution of Toll-like receptors to the pathogenesis of asthma. Immunol. Cell Biol. 85: 463-470 (2007). *

• Phipps S, Lam CE, Kaiko GE, Foo SY, Collison A, Mattes J, Barry J, Davidson S, Oreo K, Smith L, Mansell A, Matthaei KI, Foster PS. Toll/IL-1 signaling is critical for house dust mite-specific Th1 and Th2 responses. Am. J. Respir. Crit. Care Med. 179: 883-893 (2009). *

• Piavaux B, Jeurink PV, Groot PC, Hofman GA, Demant P, Van Oosterhout AJ. Mouse genetic model for antigen-induced airway manifestations of asthma. Genes Immun. 8: 28-34 (2007). *

• Piconi S, Trabattoni D, Saresella M, Iemoli E, Schenal M, Fusi A, Borelli M, Chen L, Mascheri A, Clerici M. Effects of specific immunotherapy on the B7 family of costimulatory molecules in allergic inflammation. J. Immunol. 178: 1931-1937 (2007). *

• Pietruszewska W, Olejniczak I, Durko T, Mlynarski W. Role of IFN-gamma and TNF-alpha in etiology of nasal polyps - initial studies. Otolaryngol. Pol. 62: 54-58 (2008).

• Pihet M, Carrere J, Cimon B, Chabasse D, Delhaes L, Symoens F, Bouchara JP. Occurrence and relevance of filamentous fungi in respiratory secretions of patients with cystic fibrosis - a review. Med. Mycol. 47: 387-397 (2009). *

• Pillemer BB, Qi Z, Melgert B, Oriss TB, Ray P, Ray A. STAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells. J. Immunol. 183: 155-163 (2009).

• Pinto LA, Steudemann L, Depner M, Klopp N, Illig T, Weiland SK, von Mutius E, Kabesch M. STAT1 gene variations, IgE regulation and atopy. Allergy 62: 1456-1461 (2007). *

• Pisi G, Olivieri D, Chetta A. The airway neurogenic inflammation: clinical and pharmacological implications. Inflamm. Allergy Drug Targets 8: 176-181 (2009).

• Platts-Mills TA, Erwin E, Heymann P, Woodfolk J. Is the hygiene hypothesis still a viable explanation for the increased prevalence of asthma? Allergy 60 Suppl. 79: 25-31 (2005).

• Platzer B, Richter S, Kneidinger D, Waltenberger D, Woisetschlager M, Strobl H. Aryl hydrocarbon receptor activation inhibits in vitro differentiation of human monocytes and Langerhans dendritic cells. J. Immunol. 183: 66-74 (2009).

• Pletz MW, Sauer-Heilborn A, Kohnlein T, Seidler U, Lamprecht G. Cystic fibrosis in adults. Internist (Berl.) Feb 4 [Epub ahead of print] (2010).

• Podesta A, Lopez P, Terg R, Villamil F, Flores D, Mastai R, Udaondo CB, Companc JP. Treatment of pruritus of primary biliary cirrhosis with rifampin. Dig. Dis. Sci. 36: 216-220 (1991).

• Politt D, Heintz B, Floege J, Mertens PR. Tacrolimus-(FK 506) based immunosuppression in severe systemic lupus erythematosus. Clin. Nephrol. 62: 49-53 (2004).

• Polman CH, O'Connor PW, Havrdova E, Hutchinson M, Kappos L, Miller DH, Phillips JT, Lublin FD, Giovannoni G, Wajgt A, Toal M, Lynn F, Panzara MA, Sandrock AW; AFFIRM Investigators. A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis. N. Engl. J. Med. 354: 899-910 (2006). *

• Polonikov AV, Ivanov VP, Solodilova MA, Khoroshaya IV, Kozhuhov MA, Panfilov VI. Promoter polymorphism G-50T of a human CYP2J2 epoxygenase gene is associated with common susceptibility to asthma. Chest 132: 120-126 (2007). *

• Polonikov AV, Ivanov VP, Solodilova MA, Kozhuhov MA, Panfilov VI. Tobacco smoking, fruit and vegetable intake modify association between -21A>T polymorphism of catalase gene and risk of bronchial asthma. J. Asthma 46: 217-224 (2009).

• Ponomarenko NA, Durova OM, Vorobiev II, Belogurov AA Jr, Kurkova IN, Petrenko AG, Telegin GB, Suchkov SV, Kiselev SL, Lagarkova MA, Govorun VM, Serebryakova MV, Avalle B, Tornatore P, Karavanov A, Morse HC 3rd, Thomas D, Friboulet A, Gabibov AG. Autoantibodies to myelin basic protein catalyze site-specific degradation of their antigen. Proc. Natl. Acad. Sci. U.S.A. 103: 281-286 (2006). *

• Poole JA, Barriga K, Leung DY, Hoffman M, Eisenbarth GS, Rewers M, Norris JM. Timing of initial exposure to cereal grains and the risk of wheat allergy. Pediatrics 117: 2175-2182 (2006). *

• Poon AH, Laprise C, Lemire M, Hudson TJ, Schurr E. NRAMP1 is not associated with asthma, atopy, and serum immunoglobulin E levels in the French Canadian population. Genes Immun. 6: 519-527 (2005). *

• Post-White J, Ladas EJ, Kelly KM. Advances in the use of milk thistle (Silybum marianum). Integr. Cancer Ther. 6: 104-109 (2007). *

• Potaczek DP, Maeda K, Wang QH, Nakano N, Kanada S, Stepien E, Branicka A, Fukai T, Hara M, Tokura T, Ogawa H, Undas A, Okumura K, Nishiyama C. FcepsilonRIalpha gene -18483A>C polymorphism affects transcriptional activity through YY1 binding. Immunogenetics 61: 649-655 (2009). *

• Potaczek DP, Sanak M, Mastalerz L, Setkowicz M, Kaczor M, Nizankowska E, Szczeklik A. The alpha-chain of high-affinity receptor for IgE (FcepsilonRIalpha) gene polymorphisms and serum IgE levels. Allergy 61: 1230-1233 (2006). *

• Pouliot P, Bergeron S, Marette A, Olivier M. The role of protein tyrosine phosphatases in the regulation of allergic asthma: implication of TC-PTP and PTP-1B in the modulation of disease development. Immunology 128: 534-542 (2009). *

• Pouliot P, Camateros P, Radzioch D, Lambrecht BN, Olivier M. Protein tyrosine phosphatases regulate asthma development in a murine asthma model. J. Immunol. 182: 1334-1340 (2009).

• Pouliot P, Willart MA, Hammad H, Lambrecht BN. Studying the function of dendritic cells in mouse models of asthma. Methods Mol. Biol. 595: 331-349 (2010).

• Powell N, Huntley B, Beech T, Knight W, Knight H, Corrigan CJ. Increased prevalence of gastrointestinal symptoms in patients with allergic disease. Postgrad. Med. J. 83: 182-186 (2007). *

• Prandota J, Stolarczyk J. Autoimmune hepatitis associated with the odour of fish food proteins: a causal relationship or just a mere association? Allergol. Immunopathol. (Madr.) 30: 331-337 (2002).

• Prescott SL, Calder PC. n-3 Polyunsaturated fatty acids and allergic disease. Curr. Opin. Clin. Nutr. Metab. Care 7: 123-129 (2004).

• Prescott SL, Clifton V. Asthma and pregnancy: emerging evidence of epigenetic interactions in utero. Curr. Opin. Allergy Clin. Immunol. 9: 417-426 (2009).

• Prescott SL, Dunstan JA. Prenatal fatty acid status and immune development: the pathways and the evidence. Lipids 42: 801-810 (2007).

• Prescott SL, Dunstan JA, Barden AE, Mori TA. Maternal fish oil supplementation in pregnancy modifies neonatal leukotriene production by cord blood derived neutrophils. Clin. Sci. (Lond.) 113: 409-416 (2007). *

• Prescott SL, Irvine J, Dunstan JA, Hii C, Ferrante A. Protein kinase Czeta: a novel protective neonatal T-cell marker that can be upregulated by allergy prevention strategies. J. Allergy Clin. Immunol. 120: 200-206 (2007). *

• Prescott SL, Smith P, Tang M, Palmer DJ, Sinn J, Huntley SJ, Cormack B, Heine RG, Gibson RA, Makrides M. The importance of early complementary feeding in the development of oral tolerance: concerns and controversies. Pediatr. Allergy Immunol. 19: 375-380 (2008). *

• Principi N, Esposito S. New insights into pediatric rhinosinusitis. Pediatr. Allergy Immunol. 18 Suppl. 18: 7-9 (2007).

• Prioult G, Nagler-Anderson C. Mucosal immunity and allergic responses: lack of regulation and/or lack of microbial stimulation? Immunol. Rev. 206: 204-218 (2005). *

• Pritchard DI, Hewitt C, Moqbel R. The relationship between immunological responsiveness controlled by T-helper 2 lymphocytes and infections with parasitic helminths. Parasitology 115: S33-S44 (1997).

• Prussin C, Lee J, Foster B. Eosinophilic gastrointestinal disease and peanut allergy are alternatively associated with IL-5(+) and IL-5(-) T(H)2 responses. J. Allergy Clin. Immunol. 124: 1326-1332.e6 (2009). *

• Przybylik-Mazurek E, Kotlinowska B, Kasztelnik M, Stefanska A, Huszno B. Autoimmunological and allergic disorders with Hashimoto and Graves disease. Przegl. Lek. 63: 719-722 (2006).

• Puccetti P, Grohmann U. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat. Rev. Immunol. 7: 817-823 (2007). *

• Puchner TC, Kugathasan S, Kelly KJ, Binion DG. Successful desensitization and therapeutic use of infliximab in adult and pediatric Crohn's disease patients with prior anaphylactic reaction. Inflamm. Bowel Dis. 7: 34-37 (2001). *

• Pujols L, Mullol J, Torrego A, Picado C. Glucocorticoid receptors in human airways. Allergy 59: 1042-1052 (2004). *

• Purdy JK, Appelman HD, Golembeski CP, McKenna BJ. Lymphocytic esophagitis: a chronic or recurring pattern of esophagitis resembling allergic contact dermatitis. Am. J. Clin. Pathol. 130: 508-513 (2008). *

• Puxeddu I, Berkman N, Ribatti D, Bader R, Haitchi HM, Davies DE, Howarth PH, Levi-Schaffer F. Osteopontin is expressed and functional in human eosinophils. Allergy 65: 168-174 (2010). *

• Qiao HL, Gao N, Jia LJ, Yang J, Tian X. Specific IgG antibodies in sera in patients with penicillin allergy. Clin. Exp. Med. 9: 105-111 (2009). *

• Qiao HL, Yang J, Zhang YW. Relationships between specific serum IgE, cytokines and polymorphisms in the IL-4, IL-4Ralpha in patients with penicillins allergy. Allergy 60: 1053-1059 (2005). *

• Qin XJ, Shi HZ, Qin SM, Kang LF, Huang CP, Zhong XN. Effects of allergen inhalation and oral glucocorticoid on serum soluble CTLA-4 in allergic asthmatics. Allergy 60: 774-779 (2005). *

• Qu SH, Li M, Huang YJ, Ou ZY, Lin ZB, Liang JP, Lu WS. Effects of allergen and intranasal glucocorticoid on Th17 and RORgamma t in peripheral blood in patients with allergic rhinitis. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 44: 996-1000 (2009).

• Rabin RL, Levinson AI. The nexus between atopic disease and autoimmunity: a review of the epidemiological and mechanistic literature. Clin. Exp. Immunol. 153: 19-30 (2008). *

• Racke MK, Ratts RB, Arredondo L, Perrin PJ, Lovett-Racke A. The role of costimulation in autoimmune demyelination. J. Neuroimmunol. 107: 205-215 (2000).

• Radon K, Windstetter D, Poluda AL, Mueller B, Mutius E, Koletzko S; Chronische Autoimmunerkrankungen und Kontakt zu Tieren (Chronic Autoimmune Disease and Animal Contact) Study Group. Contact with farm animals in early life and juvenile inflammatory bowel disease: a case-control study. Pediatrics 120: 354-361 (2007). *

• Raghavenra H, Diwakr BT, Lokesh BR, Naidu KA. Eugenol - the active principle from cloves inhibits 5-lipoxygenase activity and leukotriene-C4 in human PMNL cells. Prostaglandins Leukot. Essent. Fatty Acids 74: 23-27 (2006). *

• Raikwar HP, Muthian G, Rajasingh J, Johnson C, Bright JJ. PPARgamma antagonists exacerbate neural antigen-specific Th1 response and experimental allergic encephalomyelitis. J. Neuroimmunol. 167: 99-107 (2005).

• Raikwar HP, Muthian G, Rajasingh J, Johnson CN, Bright JJ. PPARgamma antagonists reverse the inhibition of neural antigen-specific Th(1) response and experimental allergic encephalomyelitis by ciglitazone and 15-deoxy-delta(12,14)-prostaglandin J(2). J. Neuroimmunol. 178: 76-86 (2006).

• Rainone F. Milk thistle. Am. Fam. Physician 72: 1285-1288 (2005). *

• Raithel M, Winterkamp S, Weidenhiller M, Muller S, Hahn EG. Combination therapy using fexofenadine, disodium cromoglycate, and a hypoallergenic amino acid-based formula induced remission in a patient with steroid-dependent, chronically active ulcerative colitis. Int. J. Colorectal Dis. 22: 833-839 (2007). *

• Ram R, Ben-Bassat I, Shpilberg O, Polliack A, Raanani P. The late adverse events of rituximab therapy - rare but there! Leuk. Lymphoma. 50: 1083-1095 (2009).

• Ramaprakash H, Ito T, Standiford TJ, Kunkel SL, Hogaboam CM. Toll-like receptor 9 modulates immune responses to Aspergillus fumigatus conidia in immunodeficient and allergic mice. Infect. Immun. 77: 108-119 (2009). *

• Rampey AM, Lathers DM, Woodworth BA, Schlosser RJ. Immunolocalization of dendritic cells and pattern recognition receptors in chronic rhinosinusitis. Am. J. Rhinol. 21: 117-121 (2007).

• Ramsey CD, Celedon JC. The hygiene hypothesis and asthma. Curr. Opin. Pulm. Med. 11: 14-20 (2005).

• Rapaka RR, Kolls JK. Pathogenesis of allergic bronchopulmonary aspergillosis in cystic fibrosis: current understanding and future directions. Med. Mycol. 47 Suppl. 1: S331-S337 (2009). *

• Rate A, Upham JW, Bosco A, McKenna KL, Holt PG. Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. J. Immunol. 182: 72-83 (2009). *

• Raty S, Sand J, Pulkkinen M, Matikainen M, Nordback I. Post-ERCP pancreatitis: reduction by routine antibiotics. J. Gastrointest. Surg. 5: 339-345 (2001).

• Rautava S, Isolauri E. The development of gut immune responses and gut microbiota: effects of probiotics in prevention and treatment of allergic disease. Curr. Issues Intest. Microbiol. 3: 15-22 (2002).

• Rautava S, Ruuskanen O, Ouwehand A, Salminen S, Isolauri E. The hygiene hypothesis of atopic disease - an extended version. J. Pediatr. Gastroenterol. Nutr. 38: 378-388 (2004). *

• Redondo-Cerezo E, Cabello MJ, Gonzalez Y, Gomez M, Garcia-Montero M, de Teresa J. Eosinophilic gastroenteritis: our recent experience: one-year experience of atypical onset of an uncommon disease. Scand. J. Gastroenterol. 36: 1358-1360 (2001). *

• Redvall E, Bengtsson U, Wenneras C. Responsiveness of eosinophils to aeroallergens may be independent of atopic status. Scand. J. Immunol. 67: 377-384 (2008). *

• Reese TA, Liang HE, Tager AM, Luster AD, Van Rooijen N, Voehringer D, Locksley RM. Chitin induces accumulation in tissue of innate immune cells associated with allergy. Nature 447: 92-96 (2007). *

• Reiner SL. Development in motion: helper T cells at work. Cell 129: 33-36 (2007). *

• Reinhardt M, Machnik G, Krombholz B, Jahn G. The so-called dihydralazine hepatitis. A contribution to the pathogenesis. Dtsch. Z. Verdau. Stoffwechselkr. 45: 283-294 (1985).

• Reinisch W, Haas T, Kaser A, Petritsch W, Vogelsang H, Feichtenschlager T, Novacek G, Siebert F, Tilg H, Knoflach P. Adalimumab for the treatment of Crohn's disease - Consensus Paper of the Working Group "Chronic Inflammatory Bowel Diseases" of the Austrian Society for Gastroenterology and Hepatology. Z. Gastroenterol. 47: 372-380 (2009).

• Reisacher WR. Prevalence of autoimmune thyroid disease in chronic rhinitis. Ear Nose Throat J. 87: 524-527 (2008).

• Reuter S, Heinz A, Sieren M, Wiewrodt R, Gelfand E, Stassen M, Buhl R, Taube C. Mast cell-derived tumour necrosis factor is essential for allergic airway disease. Eur. Respir. J. 31: 773-782 (2008). *

• Reuter S, Taube C. Mast cells and the development of allergic airway disease. J. Occup. Med. Toxicol. 3 Suppl. 1: S2 (2008).

• Riccioni G, Bucciarelli T, Mancini B, Di Ilio C, D'Orazio N. Antileukotriene drugs: clinical application, effectiveness and safety. Curr. Med. Chem. 14: 1966-1977 (2007).

• Rickel EA, Siegel LA, Yoon BR, Rottman JB, Kugler DG, Swart DA, Anders PM, Tocker JE, Comeau MR, Budelsky AL. Identification of functional roles for both IL-17RB and IL-17RA in mediating IL-25-induced activities. J. Immunol. 181: 4299-4310 (2008). *

• Rid R, Onder K, Trost A, Bauer J, Hintner H, Ritter M, Jakab M, Costa I, Reischl W, Richter K, Macdonald S, Jendrach M, Bereiter-Hahn J, Breitenbach M. H(2)O(2)-dependent translocation of TCTP into the nucleus enables its interaction with VDR in human keratinocytes: TCTP as a further module in calcitriol signalling. J. Steroid Biochem. Mol. Biol. Oct 5 [Epub ahead of print] (2009).

• Rieder SA, Chauhan A, Singh U, Nagarkatti M, Nagarkatti P. Cannabinoid-induced apoptosis in immune cells as a pathway to immunosuppression. Immunobiology May 18 [Epub ahead of print] (2009).

• Rigoli L, Caminiti L, Di Bella C, Procopio V, Cuppari C, Vita D, Barberio G, Salpietro C, Pajno GB. Investigation of the eotaxin gene -426C-->T, -384A-->G and 67G-->A single-nucleotide polymorphisms and atopic dermatitis in Italian children using family-based association methods. Clin. Exp. Dermatol. 33: 316-321 (2008). *

• Ring S, Thome M, Pretsch L, Enk AH, Mahnke K. Expanded murine regulatory T cells: analysis of phenotype and function in contact hypersensitivity reactions. J. Immunol. Methods 326: 10-21 (2007). *

• Ringer S, Hipler UC, Elsner P, Zintl F, Mainz J. Potential role of the cellular allergen stimulation test (CAST) in diagnosis of allergic bronchopulmonary aspergillosis (ABPA) in cystic fibrosis. Pediatr. Pulmonol. 42: 314-318 (2007).

• Riscili BP, Wood KL. Noninvasive pulmonary Aspergillus infections. Clin. Chest Med. 30: 315-335, vii (2009).

• Rivera A, Ro G, Van Epps HL, Simpson T, Leiner I, Sant'angelo DB, Pamer EG. Innate immune activation and CD4(+) T cell priming during respiratory fungal infection. Immunity 25: 665-675 (2006). *

• Rivera J, Olivera A. A current understanding of Fc epsilon RI-dependent mast cell activation. Curr. Allergy Asthma Rep. 8: 14-20 (2008).

• Rizzo R, Stignani M, Amoudruz P, Nilsson C, Melchiorri L, Baricordi O, Sverremark-Ekstrom E. Allergic women have reduced sHLA-G plasma levels at delivery. Am. J. Reprod. Immunol. 61: 368-376 (2009).

• Robays LJ, Maes T, Joos GF, Vermaelen KY. Between a cough and a wheeze: dendritic cells at the nexus of tobacco smoke-induced allergic airway sensitization. Mucosal Immunol. 2: 206-219 (2009). *

• Roberts-Thomson PJ, Roberts-Thomson RA, Nikoloutsopoulos T, Gillis D. Immune dysfunction in Australian Aborigines. Asian Pac. J. Allergy Immunol. 23: 235-244 (2005).

• Robinson DS. Regulatory T cells and asthma. Clin. Exp. Allergy 39: 1314-1323 (2009). *

• Robinson DS, Larche M, Durham SR. Tregs and allergic disease. J. Clin. Invest. 114: 1389-1397 (2004). *

• Rocha-de-Souza CM, Berent-Maoz B, Mankuta D, Moses AE, Levi-Schaffer F. Human mast cell activation by Staphylococcus aureus: IL-8 and TNF-alpha release and the role of Toll-Like receptor 2 and CD48 molecules. Infect. Immun. 76: 4489-4497 (2008). *

• Rochman Y, Spolski R, Leonard WJ. New insights into the regulation of T cells by gamma(c) family cytokines. Nat. Rev. Immunol. 9: 480-490 (2009). *

• Rodrigues LC, Newcombe PJ, Cunha SS, Alcantara-Neves NM, Genser B, Cruz AA, Simoes SM, Fiaccone R, Amorim L, Cooper PJ, Barreto ML; SCAALA (Social Change, Asthma and Allergy in Latin America). Early infection with Trichuris trichiura and allergen skin test reactivity in later childhood. Clin. Exp. Allergy 38: 1769-1777 (2008).

• Rojo JM, Pini E, Ojeda G, Bello R, Dong C, Flavell RA, Dianzani U, Portoles P. CD4+ICOS+ T lymphocytes inhibit T cell activation 'in vitro' and attenuate autoimmune encephalitis 'in vivo' Int. Immunol. 20: 577-589 (2008).

• Romagnani S. Human Th17 cells. Arthritis Res. Ther. 10: 206 (2008). *

• Romagnani S. The increased prevalence of allergy and the hygiene hypothesis: missing immune deviation, reduced immune suppression, or both? Immunology 112: 352-363 (2004). *

• Romagnani S. Regulation of the T cell response. Clin. Exp. Allergy 36: 1357-1366 (2006). *

• Romagnani S. Th1/Th2 cells. Inflamm. Bowel Dis. 5: 285-294 (1999). *

• Romagnani S. T-cell subsets (Th1 versus Th2). Ann. Allergy Asthma Immunol. 85: 9-18 (2000).

• Romanholi DJ, Salgado LR. Exogenous Cushing's syndrome and glucocorticoid withdrawal. Arq. Bras. Endocrinol. Metabol. 51: 1280-1292 (2007).

• Romani L. Parasites and autoimmunity: the case of fungi. Autoimmun. Rev. 8: 129-133 (2008).

• Romano A, De Santis A, Romito A, Di Fonso M, Venuti A, Gasbarrini GB, Manna R. Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes. Ann. Allergy Asthma Immunol. 80: 433-437 (1998). *

• Romero JM, Bizzozero OA. Extracellular S-nitrosoglutathione, but not S-nitrosocysteine or NO, mediates protein S-nitrosation in rat spinal cord slices. J. Neurochem. 99: 1299-1310 (2006).

• Rook GA. Review series on helminths, immune modulation and the hygiene hypothesis: the broader implications of the hygiene hypothesis. Immunology 126: 3-11 (2009). *

• Rook GA, Adams V, Hunt J, Palmer R, Martinelli R, Brunet LR. Mycobacteria and other environmental organisms as immunomodulators for immunoregulatory disorders. Springer Semin. Immunopathol. 25: 237-255 (2004). *

• Rook GA, Brunet LR. Microbes, immunoregulation, and the gut. Gut 54: 317-320 (2005). *

• Rook GA, Martinelli R, Brunet LR. Innate immune responses to mycobacteria and the downregulation of atopic responses. Curr. Opin. Allergy Clin. Immunol. 3: 337-342 (2003).

• Rook GAW. Microecology, hygiene and mucosal immunology. Falk Symposium 140. Inflammatory Bowel Disease: Translation from Basic Research to Clinical Practice. Dubrovnik (Croatia). p. 33. May 7-8 (2004). *

• Root-Bernstein R. Antigenic complementarity in the induction of autoimmunity: a general theory and review. Autoimmun. Rev. 6: 272-277 (2007).

• Rosen H, Goetzl EJ. Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network. Nat. Rev. Immunol. 5: 560-570 (2005). *

• Rosenfeld RM, Andes D, Bhattacharyya N, Cheung D, Eisenberg S, Ganiats TG, Gelzer A, Hamilos D, Haydon RC 3rd, Hudgins PA, Jones S, Krouse HJ, Lee LH, Mahoney MC, Marple BF, Mitchell CJ, Nathan R, Shiffman RN, Smith TL, Witsell DL. Clinical practice guideline: adult sinusitis. Otolaryngol. Head Neck Surg. 137: S1-S31 (2007).

• Rosmarin D, Bush M, Scheinman PL. Patch testing a patient with allergic contact hand dermatitis who is taking infliximab. J. Am. Acad. Dermatol. 59: 145-147 (2008).

• Roth M, Black JL. An imbalance in C/EBPs and increased mitochondrial activity in asthmatic airway smooth muscle cells: novel targets in asthma therapy? Br. J. Pharmacol. 157: 334-341 (2009).

• Rothenberg ME. Eosinophilic gastrointestinal disorders (EGID). J. Allergy Clin. Immunol. 113: 11-28 (2004). *

• Rottem M, Gershwin ME, Shoenfeld Y. Allergic disease and autoimmune effectors pathways. Dev. Immunol. 9: 161-167 (2002). *

• Rottem M, Mekori YA. Mast cells and autoimmunity. Autoimmun. Rev. 4: 21-27 (2005). *

• Rottem M, Shoenfeld Y. Vaccination and allergy. Curr. Opin. Otolaryngol. Head Neck Surg. 12: 223-231 (2004).

• Rottem M, Shoenfeld Y. Asthma as a paradigm for autoimmune disease. Int. Arch. Allergy Immunol. 132: 210-214 (2003).

• Rousseau MC, Parent ME, St-Pierre Y. Potential health effects from non-specific stimulation of the immune function in early age: the example of BCG vaccination. Pediatr. Allergy Immunol. 19: 438-448 (2008). *

• Roviezzo F, D'Agostino B, Brancaleone V, De Gruttola L, Bucci M, De Dominicis G, Orlotti D, D'Aiuto E, De Palma R, Rossi F, Sorrentino R, Cirino G. Systemic administration of sphingosine-1-phosphate increases bronchial hyper-responsiveness in the mouse. Am. J. Respir. Cell. Mol. Biol. Jun 25 [Epub ahead of print] (2009). *

• Rubio JP, Speed TP, Bahlo M, Kilpatrick TJ, Foote SJ. The current state of multiple sclerosis genetic research. Ann. Acad. Med. Singapore 29: 322-330 (2000).

• Ruemmele F, Bier D, Marteau P, Rechkemmer G, Bourdet-Sicard R, Walker W, Goulet O. Clinical evidence for immunomodulatory effects of probiotic bacteria. J. Pediatr. Gastroenterol. Nutr. 48: 126-141 (2009). *

• Ruggieri M, Avolio C, Livrea P, Trojano M. Glatiramer acetate in multiple sclerosis: a review. CNS Drug Rev. 13: 178-191 (2007).

• Rumke HC, Visser HK. Childhood vaccinations anno 2004. II. The real and presumed side effects of vaccination. Ned. Tijdschr. Geneeskd. 148: 364-371 (2004).

• Russo AF. Anti-metallothionein IgG and levels of metallothionein in autistic families. Swiss Med. Wkly. 138: 70-77 (2008).

• Russo C, Polosa R. TNF-alpha as a promising therapeutic target in chronic asthma: a lesson from rheumatoid arthritis. Clin. Sci. (Lond.) 109: 135-142 (2005). *

• Rutgeerts PJ. Conventional treatment of Crohn's disease: objectives and outcomes. Inflamm. Bowel Dis. 7 Suppl. 1: S2-S8 (2001). *

• Rutkowski R, Stasiak-Barmuta A, Moniuszko T, Rutkowska-Rogacz D, Woinska M, Rutkowski K, Sidorczuk M. CD28 and CTLA-4 costimulatory molecules expression on T lymphocytes and NK cells in nonallergic bronchial asthma. Pol. Merkuriusz. Lek. 20: 139-44 (2006).

• Ruzza P, Biondi B, Calderan A. Therapeutic prospect of Syk inhibitors. Expert Opin. Ther. Pat. 19: 1361-1376 (2009).

• Ryan JJ, Bateman HR, Stover A, Gomez G, Norton SK, Zhao W, Schwartz LB, Lenk R, Kepley CL. Fullerene nanomaterials inhibit the allergic response. J. Immunol. 179: 665-672 (2007). *

• Ryan JJ, Kashyap M, Bailey D, Kennedy S, Speiran K, Brenzovich J, Barnstein B, Oskeritzian C, Gomez G. Mast cell homeostasis: a fundamental aspect of allergic disease. Crit. Rev. Immunol. 27: 15-32 (2007).

• Ryan MW. Diseases associated with chronic rhinosinusitis: what is the significance? Curr. Opin. Otolaryngol. Head Neck Surg. 16: 231-236 (2008).

• Rzepecka J, Donskow-Schmelter K, Doligalska M. Heligmosomoides polygyrus infection down-regulates eotaxin concentration and CCR3 expression on lung eosinophils in murine allergic pulmonary inflammation. Parasite Immunol. 29: 405-413 (2007). *

• Sabayan B, Foroughinia F, Imanieh MH. Can Campylobacter jejuni play a role in development of celiac disease? A hypothesis. World J. Gastroenterol. 13: 4784-4785 (2007). *

• Sadanaga Y, Uno M, Kitao Y, Ishikawa T. Investigation of the genetic regulation in allergic rhinitis. Auris. Nasus. Larynx. 17: 23-32 (1990).

• Sadanandam YS, Shetty MM, Rao AB, Rambabu Y. 10H-Phenothiazines: a new class of enzyme inhibitors for inflammatory diseases. Eur. J. Med. Chem. 44: 197-202 (2009).

• Saito H. Essentials for starting a pediatric clinical study (2): role of environment and immunity in the development of childhood allergic and immunologic disorders. J. Toxicol. Sci. 34: SP313-SP319 (2009).

• Saito H. Progress in allergy signal research on mast cells: systemic approach to mast cell biology in allergic diseases. J. Pharmacol. Sci. 106: 341-346 (2008). *

• Saito H. Essentials for starting a pediatric clinical study (2): role of environment and immunity in the development of childhood allergic and immunologic disorders. J. Toxicol. Sci. 34 Suppl. 2: SP313-SP319 (2009). *

• Saito Y, Kon S, Fujiwara Y, Nakayama Y, Kurotaki D, Fukuda N, Kimura C, Kanayama M, Ito K, Diao H, Matsui Y, Komatsu Y, Ohtsuka E, Uede T. Osteopontin small interfering RNA protects mice from fulminant hepatitis. Hum. Gene Ther. 18: 1205-1214 (2008).

• Sakagami T, Witherspoon DJ, Nakajima T, Jinnai N, Wooding S, Jorde LB, Hasegawa T, Suzuki E, Gejyo F, Inoue I. Local adaptation and population differentiation at the interleukin 13 and interleukin 4 loci. Genes Immun. 5: 389-397 (2004). *

• Sakarellos-Daitsiotis M, Cung MT, Sakarellos C, El Hilali Z, Kosmopoulou A, Voitharou C. Complementary peptide epitopes and anti-idiotypic antibodies in autoimmunity. Protein Pept. Lett. 11: 367-375 (2004).

• Sakashita M, Yoshimoto T, Hirota T, Harada M, Okubo K, Osawa Y, Fujieda S, Nakamura Y, Yasuda K, Nakanishi K, Tamari M. Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis. Clin. Exp. Allergy 38: 1875-1881 (2008). *

• Sakata D, Yao C, Narumiya S. Prostaglandin E(2), an immunoactivator. J. Pharmacol. Sci. Jan 6 [Epub ahead of print] (2010). *

• Sakuishi K, Oki S, Araki M, Porcelli SA, Miyake S, Yamamura T. Invariant NKT cells biased for IL-5 production act as crucial regulators of inflammation. J. Immunol. 179: 3452-3462 (2007). *

• Sala Cunill A, Soler-Palacín P, Martín De Vicente C, Labrador Horrillo M, Luengo Sanchez O, Figueras Nadal C. Common variable immunodeficiency. Prognostic factors for lung damage. Med. Clin. (Barc.) Oct 5 [Epub ahead of print] (2009).

• Sala-Vila A, Miles EA, Calder PC. Fatty acid composition abnormalities in atopic disease: evidence explored and role in the disease process examined. Clin. Exp. Allergy 38: 1432-1450 (2008). *

• Saleh A, Shan L, Halayko AJ, Kung S, Gounni AS. Critical role for STAT3 in IL-17A-mediated CCL11 expression in human airway smooth muscle cells. J. Immunol. 182: 3357-3365 (2009).

• Salek-Ardakani S, So T, Halteman BS, Altman A, Croft M. Protein kinase Ctheta controls Th1 cells in experimental autoimmune encephalomyelitis. J. Immunol. 175: 7635-7641 (2005). *

• Salib RJ. Transforming growth factor-beta gene expression studies in nasal mucosal biopsies in naturally occurring allergic rhinitis. Ann. R. Coll. Surg. Engl. 89: 563-573 (2007).

• Salobir B, S abovic M, Hojnik M, Cucnik S, Kveder T. Anti-beta2-glycoprotein I antibodies of IgM class are linked to thrombotic disorders in young women without autoimmune disease. Immunobiology 212: 193-199 (2007).

• Saltoun C, Avila PC. Advances in upper airway diseases and allergen immunotherapy in 2007. J. Allergy Clin. Immunol. 122: 481-487 (2008).

• Salvatore S, Hauser B, Devreker T, Arrigo S, Vandenplas Y. Chronic enteropathy and feeding in children: an update. Nutrition 24: 1205-1216 (2008). *

• Salvatore S, Hauser B, Vandenplas Y. Chronic enteropathy and feeding. Nestle Nutr. Workshop Ser. Pediatr. Program 59: 115-131 (2007).

• Sanchez J, Holmgren J. Cholera toxin structure, gene regulation and pathophysiological and immunological aspects. Cell. Mol. Life Sci. 65: 1347-1360 (2008). *

• Sanchez-Borges M, Acevedo N, Vergara C, Jimenez S, Zabner-Oziel P, Monzon A, Caraballo L. The A-444C polymorphism in the leukotriene C4 synthase gene is associated with aspirin-induced urticaria. J. Investig. Allergol. Clin. Immunol. 19: 375-382 (2009).

• Sanchez-Velasco P, Anton E, Munoz D, Martinez-Quesada J, Ruiz de Alegria C, Lopez-Hoyos M, Garcia-Martin A, Jimenez I, Alonso ST, Duque S, Suarez A, Jerez J, Leyva-Cobian F. Sensitivity to bee venom antigen phospholipase A2: association with specific HLA class I and class II alleles and haplotypes in beekeepers and allergic patients. Hum. Immunol. 66: 818-825 (2005).

• Sandborn WJ, Feagan BG. Review article: mild to moderate Crohn's disease - defining the basis for a new treatment algorithm. Aliment. Pharmacol. Ther. 18: 263-277 (2003). *

• Sandford AJ, Zhu S, Bai TR, Fitzgerald JM, Pare PD. The role of the C-C chemokine receptor-5 Delta32 polymorphism in asthma and in the production of regulated on activation, normal T cells expressed and secreted. J. Allergy Clin. Immunol. 108: 69-73 (2001). *

• Sandilands A, Terron-Kwiatkowski A, Hull PR, O'Regan GM, Clayton TH, Watson RM, Carrick T, Evans AT, Liao H, Zhao Y, Campbell LE, Schmuth M, Gruber R, Janecke AR, Elias PM, van Steensel MA, Nagtzaam I, van Geel M, Steijlen PM, et al. Comprehensive analysis of the gene encoding filaggrin uncovers prevalent and rare mutations in ichthyosis vulgaris and atopic eczema. Nat. Genet. 39: 650-654 (2007). *

• Sanz C, Isidoro-Garcia M, Davila I, Moreno E, Laffond E, Avila C, Lorente F. Promoter genetic variants of prostanoid DP receptor (PTGDR) gene in patients with asthma. Allergy 61: 543-548 (2006). *

• Sarma N, Ghosh S. Mycophenolate mofetil as adjuvant in pemphigus vulgaris. Indian J. Dermatol. Venereol. Leprol. 73: 348-350 (2007).

• Sawamukai N, Saito K, Yamaoka K, Nakayamada S, Ra C, Tanaka Y. Lflunomide inhibits PDK1/Akt pathway and induces apoptosis of human mast cells. J. Immunol. 179: 6479-6484 (2007). *

• Sayed BA, Christy A, Quirion MR, Brown MA. The master switch: the role of mast cells in autoimmunity and tolerance. Annu. Rev. Immunol. 26: 705-739 (2008). *

• Scabeni S, Lapilla M, Musio S, Gallo B, Ciusani E, Steinman L, Mantegazza R, Pedotti R. CD4+CD25+ regulatory T cells specific for a thymus-expressed antigen prevent the development of anaphylaxis to self. J. Immunol. 180: 4433-4440 (2008). *

• Scadding G, Scadding GK. Update on the use of nitric oxide as a noninvasive measure of airways inflammation. Rhinology 47: 115-120 (2009).

• Scarponi C, Nardelli B, Lafleur DW, Moore PA, Madonna S, De Pita O, Girolomoni G, Albanesi C. Analysis of IFN-kappa expression in pathologic skin conditions: downregulation in psoriasis and atopic dermatitis. J. Interferon Cytokine Res. 26: 133-140 (2006).

• Schack-Nielsen L, Michaelsen KF. Breast feeding and future health. Curr. Opin. Clin. Nutr. Metab. Care 9: 289-296 (2006).

• Schack-Nielsen L, Michaelsen KF. The effects of breastfeeding - I: effects on the immune system and the central nervous system. Ugeskr. Laeger. 169: 985-989 (2007).

• Schaefer C, Hidalgo TR, Cashion L, Petry H, Brooks A, Szymanski P, Qian HS, Gross C, Wang P, Liu P, Goldman C, Rubanyi GM, Harkins RN. Gene-based delivery of IFN-beta is efficacious in a murine model of experimental allergic encephalomyelitis. J. Interferon Cytokine Res. 26: 449-454 (2006).

• Schakel K. Dendritic cells - why can they help and hurt us. Exp. Dermatol. 18: 264-273 (2009).

• Schaub B, Campo M, He H, Perkins DL, Gillman MW, Gold DR, Weiss S, Lieberman E, Finn PW. Neonatal immune responses to TLR2 stimulation: influence of maternal atopy on Foxp3 and IL-10 expression. Respir. Res. 7: 40 (2006). *

• Schaub B, Liu J, Schleich I, Hoppler S, Sattler C, von Mutius E. Impairment of T helper and T regulatory cell responses at birth. Allergy 63: 1438-1447 (2008).

• Schaumann F, Muller M, Braun A, Luettig B, Peden DB, Hohlfeld JM, Krug N. Endotoxin augments myeloid dendritic cell influx into the airways in allergic asthma patients. Am. J. Respir. Crit. Care Med. 177: 1307-1313 (2008). *

• Schewitz LP, Lee RW, Dayan CM, Dick AD. Glucocorticoids and the emerging importance of T cell subsets in steroid refractory diseases. Immunopharmacol. Immunotoxicol. 31: 1-22 (2009).

• Schiffenbauer J. Superantigens and their role in autoimmune disorders. Arch. Immunol. Ther. Exp. (Warsz.) 47: 17-24 (1999).

• Schmassmann A, Halter F. Local or systemic treatment of inflammatory bowel diseases? Ther. Umsch. 50: 94-99 (1993).

• Schmidt-Weber CB. Th17 and Treg cells innovate the Th1/Th2 concept and allergy research. Chem. Immunol. Allergy 94: 1-7 (2008).

• Schmuth M, Jiang YJ, Dubrac S, Elias PM, Feingold KR. Peroxisome proliferator-activated receptors and liver X receptors in epidermal biology. J. Lipid Res. 49: 499-509 (2008). *

• Schnappinger M, Sausenthaler S, Linseisen J, Hauner H, Heinrich J. Fish consumption, allergic sensitisation and allergic diseases in adults. Ann. Nutr. Metab. 54: 67-74 (2009).

• Schneider LA, Hinrichs R, Scharffetter-Kochanek K. Phototherapy and photochemotherapy. Clin. Dermatol. 26: 464-476 (2008).

• Schnyder B, Lima C, Schnyder-Candrian S. Interleukin-22 is a negative regulator of the allergic response. Cytokine Feb 27 [Epub ahead of print] (2010).

• Schnyder-Candrian S, Togbe D, Couillin I, Mercier I, Brombacher F, Quesniaux V, Fossiez F, Ryffel B, Schnyder B. Interleukin-17 is a negative regulator of established allergic asthma. J. Exp. Med. 203: 2715-2725 (2006). *

• Schreiber R, Castrop H, Kunzelmann K. Allergen-induced airway hyperresponsiveness is absent in ecto-5'-nucleotidase (CD73)-deficient mice. Pflugers Arch. 457: 431-440 (2008). *

• Schrock A, Jakob M, Wirz S, Bootz F. Sudden sensorineural hearing loss after heroin injection. Eur. Arch. Otorhinolaryngol. 265: 603-606 (2008). *

• Schroder NW, Arditi M. IEIIS Meeting minireview. The role of innate immunity in the pathogenesis of asthma: evidence for the involvement of Toll-like receptor signaling. J. Endotoxin Res. 13: 305-312 (2007). *

• Schroder NW, Maurer M. The role of innate immunity in asthma: leads and lessons from mouse models. Allergy 62: 579-590 (2007). *

• Schubert LA, Jeffery E, Zhang Y, Ramsdell F, Ziegler SF. Scurfin (FOXP3) acts as a repressor of transcription and regulates T cell activation. J. Biol. Chem. 276: 37672-37679 (2001). *

• Schubert MS. Allergic fungal sinusitis. Clin. Rev. Allergy Immunol. 30: 205-216 (2006).

• Schubert R, Kitz R, Beermann C, Rose MA, Lieb A, Sommerer PC, Moskovits J, Alberternst H, Bohles HJ, Schulze J, Zielen S. Effect of n-3 polyunsaturated fatty acids in asthma after low-dose allergen challenge. Int. Arch. Allergy Immunol. 148: 321-329 (2008).

• Schuh JM, Blease K, Hogaboam CM. The role of CC chemokine receptor 5 (CCR5) and RANTES/CCL5 during chronic fungal asthma in mice. FASEB J. 16: 228-230 (2002). *

• Schuster GU, Kenyon NJ, Stephensen CB. Vitamin A deficiency decreases and high dietary vitamin A increases disease severity in the mouse model of asthma. J. Immunol. 180: 1834-1842 (2008). *

• Schwartzbaum J, Ahlbom A, Malmer B, Lonn S, Brookes AJ, Doss H, Debinski W, Henriksson R, Feychting M. Polymorphisms associated with asthma are inversely related to glioblastoma multiforme. Cancer Res. 65: 6459-6465 (2005). *

• Scolozzi R, Boccafogli A, Vicentini L. Hyper-IgD syndrome and other hereditary periodic fever syndromes. Reumatismo 56: 147-155 (2004).

• Sebelova S, Izakovicova-Holla L, Stejskalova A, Schuller M, Znojil V, Vasku A. Interleukin-18 and its three gene polymorphisms relating to allergic rhinitis. J. Hum. Genet. 52: 152-158 (2007). *

• Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A, Solomon M, Selby W, Alexander SI, Nanan R, Kelleher A, Fazekas de St Groth B. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells. J. Exp. Med. 203: 1693-1700 (2006). *

• Seelinger G, Merfort I, Schempp CM. Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin. Planta Med. 74: 1667-1677 (2008).

• Sehra S, Yao Y, Howell MD, Nguyen ET, Kansas GS, Leung DY, Travers JB, Kaplan MH. IL-4 regulates skin homeostasis and the predisposition toward allergic skin inflammation. J. Immunol. Feb 10 [Epub ahead of print] (2010).

• Seibold F. Food-induced immune responses as origin of bowel disease? Digestion 71: 251-260 (2005).

• Seidel-Guyenot W, Perschon S, Dechant N, Alt R, Knop J, Steinbrink K. Low zone tolerance induced by systemic application of allergens inhibits T(C)1-mediated skin inflammation. J. Allergy Clin. Immunol. 117: 1170-1177 (2006). *

• Seier AM, Renkl AC, Schulz G, Uebele T, Sindrilaru A, Iben S, Liaw L, Kon S, Uede T, Weiss JM. Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis. Am. J. Pathol. Dec 13 [Epub ahead of print] (2009). *

• Sela M. Immunomodulatory vaccines against autoimmune diseases. Rejuvenation Res. 9: 126-133 (2006).

• Sela M, Mozes E. Therapeutic vaccines in autoimmunity. Proc. Natl. Acad. Sci. U.S.A. 101: 14586-14592 (2004). *

• Selvaraj RK, Geiger TL. Mitigation of experimental allergic encephalomyelitis by TGF-beta induced Foxp3+ regulatory T lymphocytes through the induction of anergy and infectious tolerance. J. Immunol. 180: 2830-2838 (2008). *

• Semik-Orzech A, Barczyk A, Pierzchala W. The role of interleukin 17 cytokine family in inducing allergic inflammation in the pulmonary tract. Pneumonol. Alergol. Pol. 74: 409-413 (2006).

• Semik-Orzech A, Barczyk A, Wiaderkiewicz R, Pierzchala W. Interleukin 17 and RANTES levels in induced sputum of patients with allergic rhinitis after a single nasal allergen challenge. Ann. Allergy Asthma Immunol. 103: 418-424 (2009).

• Semitekolou M, Alissafi T, Aggelakopoulou M, Kourepini E, Kariyawasam HH, Kay AB, Robinson DS, Lloyd CM, Panoutsakopoulou V, Xanthou G. Activin-A induces regulatory T cells that suppress T helper cell immune responses and protect from allergic airway disease. J. Exp. Med. 206: 1769-1785 (2009). *

• Sen Y, Yongyi B, Yuling H, Luokun X, Li H, Jie X, Tao D, Gang Z, Junyan L, Chunsong H, Zhang X, Youxin J, Feili G, Boquan J, Jinquan T. V alpha 24-invariant NKT cells from patients with allergic asthma express CCR9 at high frequency and induce Th2 bias of CD3+ T cells upon CD226 engagement. J. Immunol. 175: 4914-4926 (2005). *

• Serrano-Fernandez P, Ibrahim SM, Zettl UK, Thiesen HJ, Godde R, Epplen JT, Moller S. Intergenomic consensus in multifactorial inheritance loci: the case of multiple sclerosis. Genes Immun. 5: 615-620 (2004). *

• Sertznig P, Seifert M, Tilgen W, Reichrath J. Peroxisome proliferator-activated receptors (PPARs) and the human skin: importance of PPARs in skin physiology and dermatologic diseases. Am. J. Clin. Dermatol. 9: 15-31 (2008).

• Shahabi S, Hassan ZM, Jazani NH, Ebtekar M. Sympathetic nervous system plays an important role in the relationship between immune mediated diseases. Med. Hypotheses 67: 900-903 (2006).

• Shahana S, Jaunmuktane Z, Stenkvist Asplund M, Roomans GM. Ultrastructural investigation of epithelial damage in asthmatic and non-asthmatic nasal polyps. Respir. Med. 100: 2018-2028 (2006).

• Shamim Z, Muller K, Svejgaard A, Poulsen LK, Bodtger U, Ryder LP. Association between genetic polymorphisms in the human interleukin-7 receptor alpha-chain and inhalation allergy. Int. J. Immunogenet. 34: 149-151 (2007). *

• Shan X, Hu A, Veler H, Fatma S, Grunstein JS, Chuang S, Grunstein MM. Regulation of Toll-like receptor 4-induced pro-asthmatic changes in airway smooth muscle function by opposing actions of ERK1/2 and p38 MAPK signaling. Am. J. Physiol. Lung Cell. Mol. Physiol. 291: L324-L333 (2006). *

• Shao Z, Makinde TO, McGee HS, Wang X, Agrawal DK. Fms-like tyrosine kinase 3 ligand regulates migratory pattern and antigen uptake of lung dendritic cell subsets in a murine model of allergic airway inflammation. J. Immunol. 183: 7531-7538 (2009).

• Sharma S, Rajan UM, Kumar A, Soni A, Ghosh B. A novel (TG)n(GA)m repeat polymorphism 254 bp downstream of the mast cell chymase (CMA1) gene is associated with atopic asthma and total serum IgE levels. J. Hum. Genet. 50: 276-282 (2005). *

• Shea-Donohue T, Urban JF Jr. Gastrointestinal parasite and host interactions. Curr. Opin. Gastroenterol. 20: 3-9 (2004).

• Sheikh A, Strachan DP. The hygiene theory: fact or fiction? Curr. Opin. Otolaryngol. Head Neck Surg. 12: 232-236 (2004).

• Shenoy S. Stem cell transplantation in genetically linked regulatory T-cell disorders. Chem. Immunol. Allergy 94: 211-219 (2008).

• Sherman S, Lehman GA. ERCP- and endoscopic sphincterotomy-induced pancreatitis. Pancreas 6: 350-367 (1991).

• Sheu MY, Fowler AJ, Kao J, Schmuth M, Schoonjans K, Auwerx J, Fluhr JW, Man MQ, Elias PM, Feingold KR. Topical peroxisome proliferator activated receptor-alpha activators reduce inflammation in irritant and allergic contact dermatitis models. J. Invest. Dermatol. 118: 94-101 (2002). *

• Shi HN, Walker WA. T helper cell subclasses and clinical disease states. Curr. Opin. Gastroenterol. 18: 711-716 (2002).

• Shi HZ, Qin XJ. CD4CD25 regulatory T lymphocytes in allergy and asthma. Allergy 60: 986-995 (2005). *

• Shigeno T, Katakuse M, Fujita T, Mukoyama Y, Watanabe H. Phthalate ester-induced thymic stromal lymphopoietin mediates allergic dermatitis in mice. Immunology 128: e849-e857 (2009).

• Shih A, Jackson Ii KC. Role of corticosteroids in palliative care. J. Pain Palliat. Care Pharmacother. 21: 69-76 (2007).

• Shimokawa N, Nishiyama C, Hirota T, Tamari M, Hara M, Ikeda S, Okumura K, Ogawa H. Functional analysis of a polymorphism in the promoter region of the IL-12/23p40 gene. Clin. Exp. Allergy 39: 228-235 (2009). *

• Shimomura I, Takase Y, Matsumoto S, Kuyama J, Nakajima T, Maeda H, Sugase T, Hata A, Hanada M, Okuno M. Primary sclerosing cholangitis associated with increased peripheral eosinophils and serum IgE. J. Gastroenterol. 31: 737-741 (1996).

• Shimomura Y, Mizoguchi E, Sugimoto K, Kibe R, Benno Y, Mizoguchi A, Bhan AK. Regulatory role of B-1 B cells in chronic colitis. Int. Immunol. 20: 729-737 (2008). *

• Shimura C, Satoh T, Igawa K, Aritake K, Urade Y, Nakamura M, Yokozeki H. Dendritic cells express hematopoietic prostaglandin D synthase and function as a source of prostaglandin D2 in the skin. Am. J. Pathol. Dec 14 [Epub ahead of print] (2009). *

• Shin HD, Kim LH, Park BL, Choi YH, Park HS, Hong SJ, Choi BW, Lee JH, Park CS. Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients. Allergy 60: 900-906 (2005). *

• Shin HD, Kim LH, Park BL, Jung JH, Kim JY, Chung IY, Kim JS, Lee JH, Chung SH, Kim YH, Park HS, Choi JH, Lee YM, Park SW, Choi BW, Hong SJ, Park CS. Association of Eotaxin gene family with asthma and serum total IgE. Hum. Mol. Genet. 12: 1279-1285 (2003). *

• Shin SH, Ye MK. Th2 responses elicited by nasal epithelial cells exposed to house dust mite extract. Clin. Exp. Otorhinolaryngol. 2: 175-180 (2009).

• Shin TY, Oh JM, Choi BJ, Park WH, Kim CH, Jun CD, Kim SH. Anti-inflammatory effect of Poncirus trifoliata fruit through inhibition of NF-kappaB activation in mast cells. Toxicol. In Vitro 20: 1071-1076 (2006).

• Shiohara T, Inaoka M, Kano Y. Drug-induced hypersensitivity syndrome (DIHS): a reaction induced by a complex interplay among herpesviruses and antiviral and antidrug immune responses. Allergol. Int. 55: 1-8 (2006). *

• Shiota N, Kovanen PT, Eklund KK, Shibata N, Shimoura K, Niibayashi T, Shimbori C, Okunishi H. The anti-allergic compound tranilast attenuates inflammation and inhibits bone destruction in collagen-induced arthritis in mice. Br. J. Pharmacol. Jan 8 [Epub ahead of print] (2010). *

• Shiotani A, Miyanishi T, Kamada T, Haruma K. Helicobacter pylori infection and allergic diseases: epidemiological study in Japanese university students. J. Gastroenterol. Hepatol. 23: e29-e33 (2008). *

• Shoenfelt J, Mitkus RA, Zeisler R, Spatz RO, Powell J, Fenton MJ, Squibb KA, Medvedev AE. Involvement of TLR2 and TLR4 in inflammatory immune responses induced by fine and coarse ambient air particulate matter. J. Leukoc. Biol. 86: 303-312 (2009). *

• Shternshis IuA, Sveranovskaia VV, Samoilikov PV. Epitope mimicry and its role in the development of autoimmune reactions. Zh. Mikrobiol. Epidemiol. Immunobiol. 1: 96-100 (2005).

• Shum BO, Rolph MS, Sewell WA. Mechanisms in allergic airway inflammation - lessons from studies in the mouse. Expert Rev. Mol. Med. 10: e15 (2008).

• Shurin MR, Smolkin YS. Immune-Mediated Diseases II Congress: summary. J. Immunotoxicol. 5: 159-162 (2008).

• Shurin MR, Smolkin YS. Immune-mediated diseases: where do we stand? Adv. Exp. Med. Biol. 601: 3-12 (2007).

• Sicherer SH, Sampson HA. Food allergy: recent advances in pathophysiology and treatment. Annu. Rev. Med. 60: 261-277 (2009). *

• Sicotte NL, Giesser BS, Tandon V, Klutch R, Steiner B, Drain AE, Shattuck DW, Hull L, Wang HJ, Elashoff RM, Swerdloff RS, Voskuhl RR. Testosterone treatment in multiple sclerosis: a pilot study. Arch. Neurol. 64: 683-688 (2007).

• Siegrist CA, Lewis EM, Eskola J, Evans SJ, Black SB. Human papilloma virus immunization in adolescent and young adults: a cohort study to illustrate what events might be mistaken for adverse reactions. Pediatr. Infect. Dis. J. 26: 979-984 (2007).

• Sieper J, Braun J. Anti-TNF agents for the treatment of spondyloarthropathies. Expert Opin. Emerg. Drugs 7: 235-246 (2002).

• Sikder H, Zhao Y, Balato A, Chapoval A, Fishelevich R, Gade P, Singh IS, Kalvakolanu DV, Johnson PF, Gaspari AA. A central role for transcription factor C/EBP-beta in regulating CD1d gene expression in human keratinocytes. J. Immunol. 183: 1657-1666 (2009).

• Silva ML, Espírito-Santo LR, Martins MA, Silveira-Lemos D, Peruhype-Magalhaes V, Caminha RC, de Andrade Maranhao-Filho P, Martins MA, de Menezes Martins R, Galler R, Freire MD, Marcovistz R, Homma A, Teuwen DE, Eloi-Santos SM, Andrade MC, et al. Clinical and immunological insights on severe adverse neurotropic/viscerotropic disease following 17D yellow fever vaccination. Clin. Vaccine Immunol. Nov 11 [Epub ahead of print] (2009). *

• Simmonds NJ, Cullinan P, Hodson ME. Growing old with cystic fibrosis - the characteristics of long-term survivors of cystic fibrosis. Respir. Med. 103: 629-635 (2009).

• Simoes DC, Xanthou G, Petrochilou K, Panoutsakopoulou V, Roussos C, Gratziou C. Osteopontin deficiency protects against airway remodeling and hyperresponsiveness in chronic asthma. Am. J. Respir. Crit. Care Med. 179: 894-902 (2009). *

• Simpson A, John SL, Jury F, Niven R, Woodcock A, Ollier WE, Custovic A. Endotoxin exposure, CD14 and allergic disease: an interaction between genes and the environment. Am. J. Respir. Crit. Care Med. 174: 386-392 (2006). *

• Sims P, Coffman RL, Hessel EM. Biomarkers measuring the activity of Toll-like receptor ligands in clinical development programs. Methods Mol. Biol. 517: 1-26 (2009).

• Singh D, Rani R, Rajendran R, Kaur NJ, Pandey A, Chopra P, Jain T, Jain MK, Grover S, Arya R, Saini KS. Human spleen tyrosine kinase (Syk) recombinant expression systems for high-throughput assays. Biotechnol. J. Dec 14 [Epub ahead of print] (2009).

• Singh NP, Hegde V, Hofseth LJ, Nagarkatti M, Nagarkatti P. Resveratrol (trans-3,5,4'-trihydroxystilbene) ameliorates experimental allergic encephalomyelitis (EAE) primarily via induction of apoptosis in T cells involving activation of AhR and ER. Mol. Pharmacol. 72: 1508-1521 (2007). *

• Siqueira Neto JI, Costa AC, Magalhaes FG, Silva GS. Neurological manifestations of celiac disease. Arq. Neuropsiquiatr. 62: 969-972 (2004). *

• Sjogren YM, Tomicic S, Lundberg A, Bottcher MF, Bjorksten B, Sverremark-Ekstrom E, Jenmalm MC. Influence of early gut microbiota on the maturation of childhood mucosal and systemic immune responses. Clin. Exp. Allergy Sep 3 [Epub ahead of print] (2009). *

• Skinner ML, Schlosser RJ, Lathers D, Neal JG, Woodworth BA, Hall J, Newton DA, Baatz JE. Innate and adaptive mediators in cystic fibrosis and allergic fungal rhinosinusitis. Am. J. Rhinol. 21: 538-541 (2007).

• Skov M, McKay K, Koch C, Cooper PJ. Prevalence of allergic bronchopulmonary aspergillosis in cystic fibrosis in an area with a high frequency of atopy. Respir. Med. 99: 887-893 (2005).

• Skripuletz T, Schmiedl A, Schade J, Bedoui S, Glaab T, Pabst R, von Horsten S, Stephan M. Dose dependent recruitment of CD25+ and CD26+ T cells in a novel F344 rat model of asthma. Am. J. Physiol. Lung Cell. Mol. Physiol. 292: L1564-L1571 (2007). *

• Skvara H, Dawid M, Kleyn E, Wolff B, Meingassner JG, Knight H, Dumortier T, Kopp T, Fallahi N, Stary G, Burkhart C, Grenet O, Wagner J, Hijazi Y, Morris RE, McGeown C, Rordorf C, Griffiths CE, Stingl G, Jung T. The PKC inhibitor AEB071 may be a therapeutic option for psoriasis. J. Clin. Invest. 118: 3151-3159 (2008). *

• Slade HB, Shroot B, Feldman SR, Cargill DI, Stanfield J. Reappraising the phototoxicity of tretinoin: a report of four controlled clinical trials. Photodermatol. Photoimmunol. Photomed. 25: 146-152 (2009).

• Slovik Y, Putterman M, Nash M, Sion-Vardy N. Eosinophilic angiocentric fibrosis of the sinonasal tract in a male patient with chronic bowel inflammation. Am. J. Rhinol. 20: 91-94 (2006).

• Smit JJ, Folkerts G, Nijkamp FP. Mycobacteria, genes and the 'hygiene hypothesis'. Curr. Opin. Allergy Clin. Immunol. 4: 57-62 (2004).

• Smit JJ, Van Loveren H, Hoekstra MO, Karimi K, Folkerts G, Nijkamp FP. The Slc11a1 (Nramp1) gene controls efficacy of mycobacterial treatment of allergic asthma. J. Immunol. 171: 754-760 (2003). *

• Smit JJ, van Loveren H, Hoekstra MO, Nijkamp FP, Bloksma N. Influence of the macrophage bacterial resistance gene, Nramp1 (Slc11a1), on the induction of allergic asthma in the mouse. FASEB J. 17: 958-960 (2003). *

• Smits HH, Engering A, Van der Kleij D, De Jong EC, Schipper K, Van Capel TM, Zaat BA, Yazdanbakhsh M, Wierenga EA, Van Kooyk Y, Kapsenberg ML. Selective probiotic bacteria induce IL-10-producing regulatory T cells in vitro by modulating dendritic cell function through dendritic cell-specific intercellular adhesion molecule 3-grabbing nonintegrin. J. Allergy Clin. Immunol. 115: 1260-1267 (2005). *

• Smits HH, Gloudemans AK, van Nimwegen M, Willart MA, Soullie T, Muskens F, de Jong EC, Boon L, Pilette C, Johansen FE, Hoogsteden HC, Hammad H, Lambrecht BN. Cholera toxin B suppresses allergic inflammation through induction of secretory IgA. Mucosal Immunol. 2: 331-339 (2009). *

• Smole U, Balazs N, Hoffmann-Sommergruber K, Radauer C, Hafner C, Wallner M, Ferreira F, Grossinger R, de Jong EC, Wagner S, Breiteneder H. Differential T-cell responses and allergen uptake after exposure of dendritic cells to the birch pollen allergens Bet v 1.0101, Bet v 1.0401 and Bet v 1.1001. Immunobiology Dec 14 [Epub ahead of print] (2009).

• Soares MF, Macedo MS. Modulation of anaphylaxis by helminth-derived products in animal models. Curr. Allergy Asthma Rep. 7: 56-61 (2007).

• Sobiesiak M, Shumilina E, Lam RS, Wolbing F, Matzner N, Kaesler S, Zemtsova IM, Lupescu A, Zahir N, Kuhl D, Schaller M, Biedermann T, Lang F. Impaired mast cell activation in gene-targeted mice lacking the serum- and glucocorticoid-inducible kinase SGK1. J. Immunol. 183: 4395-4402 (2009).

• Sohn MH, Kim SH, Song TW, Kim KW, Kim ES, Park HS, Kim KE. Cytotoxic T lymphocyte-associated antigen-4 gene polymorphisms confer susceptibility to atopic asthma in Korean children. Pediatr. Pulmonol. 42: 542-547 (2007).

• Sohn MH, Lee JH, Kim KW, Kim SW, Lee SH, Kim KE, Kim KH, Lee CG, Elias JA, Lee MG. Genetic variation in the promoter region of chitinase 3-like 1 (CHI3L1) is associated with atopy. Am. J. Respir. Crit. Care Med. 179: 449-456 (2009). *

• Sohn SH, Kim SK, Ko E, Lee Y, Chung HS, Lee H, Kim H, Hwang DS, Nam S, Bae H. The genome-wide expression profile of electroacupuncture in DNP-KLH immunized mice. Cell. Mol. Neurobiol. Dec 30 [Epub ahead of print] (2009).

• Sonderegger I, Iezzi G, Maier R, Schmitz N, Kurrer M, Kopf M. GM-CSF mediates autoimmunity by enhancing IL-6-dependent Th17 cell development and survival. J. Exp. Med. 205: 2281-2294 (2008). *

• Song C, Luo L, Lei Z, Li B, Liang Z, Liu G, Li D, Zhang G, Huang B, Feng ZH. IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma. J. Immunol. 181: 6117-6124 (2008). *

• Soond DR, Bjorgo E, Moltu K, Dale VQ, Patton DT, Torgersen KM, Galleway F, Twomey B, Clark J, Gaston JH, Tasken K, Bunyard P, Okkenhaug K. PI3K p110delta regulates T cell cytokine production during primary and secondary immune responses in mice and humans. Blood Jan 15 [Epub ahead of print] (2010). *

• Soos JM, Johnson HM. Interferon-tau: prospects for clinical use in autoimmune disorders. BioDrugs 11: 125-135 (1999).

• Soroosh P, Doherty TA. Th9 and allergic disease. Immunology 127: 450-458 (2009). *

• Sorribes MM, Welinder NR, Stangerup SE. Anti-neutrophil cytoplasmic antibody-associated mucocutaneous allergic vasculitis with oral manifestations caused by propylthiouracil. J. Laryngol. Otol. 113: 477-479 (1999).

• Soruri A, Grigat J, Kiafard Z, Zwirner J. Mast cell activation is characterized by upregulation of a functional anaphylatoxin C5a receptor. BMC Immunol. 9: 29 (2008). *

• Southward J, Irvine E, Rabinovich M. Probable amlodipine-induced angioedema. Ann. Pharmacother. 43: 772-776 (2009).

• Spach KM, Blake M, Bunn JY, McElvany B, Noubade R, Blankenhorn EP, Teuscher C. Cutting edge: the Y chromosome controls the age-dependent experimental allergic encephalomyelitis sexual dimorphism in SJL/J mice. J. Immunol. 182: 1789-1793 (2009).

• Spach KM, Noubade R, McElvany B, Hickey WF, Blankenhorn EP, Teuscher C. A single nucleotide polymorphism in Tyk2 controls susceptibility to experimental allergic encephalomyelitis. J. Immunol. 182: 7776-7783 (2009).

• Spazierer D, Skvara H, Dawid M, Fallahi N, Gruber K, Rose K, Lloyd P, Heuerding S, Stingl G, Jung T. T helper 2 biased de novo immune response to keyhole limpet hemocyanin in humans. Clin. Exp. Allergy 39: 999-1008 (2009). *

• Speiran K, Bailey DP, Fernando J, Macey M, Barnstein B, Kolawole M, Curley D, Watowich SS, Murray PJ, Oskeritzian C, Ryan JJ. Endogenous suppression of mast cell development and survival by IL-4 and IL-10. J. Leukoc. Biol. 85: 826-836 (2009). *

• Spiegl N, Didichenko S, McCaffery P, Langen H, Dahinden CA. Human basophils activated by mast cell-derived IL-3 express retinaldehyde dehydrogenase-II and produce the immunoregulatory mediator retinoic acid. Blood 112: 3762-3771 (2008). *

• Spivak NIa, Bogdanova IM, Martirosova NI, Malaitsev VV. The role of Toll-like receptors in regulation of immune responses in norm and pathology. Fiziol. Zh. 54: 87-99 (2008).

• Spond J, Case N, Chapman RW, Crawley Y, Egan RW, Fine J, Hey JA, Kreutner W, Kung T, Wang P, Minnicozzi M. Inhibition of experimental acute pulmonary inflammation by pirfenidone. Pulm. Pharmacol. Ther. 16: 207-214 (2003).

• Srivastava MD, Kulaylat MN. Gene expression profiles of late colonic Crohn's disease. J. Med. 35: 233-255 (2004).

• St Clair EW, Turka LA, Saxon A, Matthews JB, Sayegh MH, Eisenbarth GS, Bluestone J. New reagents on the horizon for immune tolerance. Annu. Rev. Med. 58: 329-346 (2007). *

• St-Amour I, Laroche A, Bazin R, Lemieux R. Activation of cryptic IgG reactive with BAFF, amyloid beta peptide and GM-CSF during the industrial fractionation of human plasma into therapeutic intravenous immunoglobulins. Clin. Immunol. 133: 52-60 (2009). *

• Staelens J, Puimege L, Mahieu T, Pynaert G, Hochepied T, Vandenabeele A, Grooten J, Kontoyiannis D, Van Roy F, Kollias G, Libert C. Response of TNF-hyporesponsive SPRET/Ei mice in models of inflammatory disorders. Mamm. Genome 15: 537-543 (2004).

• Staines DR, Brenu EW, Marshall-Gradisnik S. Postulated vasoactive neuropeptide immunopathology affecting the blood-brain/blood-spinal barrier in certain neuropsychiatric fatigue-related conditions: a role for phosphodiesterase inhibitors in treatment? Neuropsychiatr. Dis. Treat. 5: 81-89 (2009).

• Stange EF. Immunosuppressors in inflammatory bowel disease. Falk Symposium 154: INFLAMMATORY BOWEL DISEASE - DIAGNOSTIC AND THERAPEUTIC STRATEGIES, Moscow (Russia), June 9 - 10, 2006, p. 53 (2006). *

• Stanislaus R, Gilg AG, Singh AK, Singh I. N-acetyl-L-cysteine ameliorates the inflammatory disease process in experimental autoimmune encephalomyelitis in Lewis rats. J. Autoimmune Dis. 2: 4 (2005). *

• Stazi F, Farello P, Stazi C. Intrahepatic cholestasis Clin. Ter. 147: 575-583 (1996).

• Steele RW. Rhinosinusitis in children. Curr. Allergy Asthma Rep. 6: 508-512 (2006).

• Stein RB, Hanauer SB. Comparative tolerability of treatments for inflammatory bowel disease. Drug Saf. 23: 429-448 (2000).

• Steinke JW, Barekzi E, Hagman J, Borish L. Functional analysis of -571 IL-10 promoter polymorphism reveals a repressor element controlled by Sp1. J. Immunol. 173: 3215-3222 (2004). *

• Steinke JW, Barekzi E, Huyett P, Borish L. Differential interleukin-10 production stratified by -571 promoter polymorphism in purified human immune cells. Cell. Immunol. 249: 101-107 (2007). *

• Steinke JW, Borish L. Cytokines and chemokines. J. Allergy Clin. Immunol. 117: S441-S445 (2006).

• Steinke JW, Borish L. Genetics of allergic disease. Med. Clin. North Am. 90: 1-15 (2006).

• Steinke JW, Rich SS, Borish L. 5. Genetics of allergic disease. J. Allergy Clin. Immunol. 121: S384-S387 (2008). *

• Steinman L. A brief history of T(H)17, the first major revision in the T(H)1/T(H)2 hypothesis of T cell-mediated tissue damage. Nat. Med. 13: 139-145 (2007). *

• Steinman L, Zamvil SS. How to successfully apply animal studies in experimental allergic encephalomyelitis to research on multiple sclerosis. Ann. Neurol. 60: 12-21 (2006).

• Stejskal V, Hudecek R, Stejskal J, Sterzl I. Diagnosis and treatment of metal-induced side-effects. Neuro. Endocrinol. Lett. 27 Suppl. 1: 7-16 (2006).

• Stelekati E, Orinska Z, Bulfone-Paus S. Mast cells in allergy: innate instructors of adaptive responses. Immunobiology 212: 505-519 (2007).

• Stock P, Lombardi V, Kohlrautz V, Akbari O. Induction of airway hyperreactivity by IL-25 is dependent on a subset of invariant NKT cells expressing IL-17RB. J. Immunol. 182: 5116-5122 (2009).

• Stojakovic M, Salazar-Fontana LI, Tatari-Calderone Z, Badovinac VP, Santori FR, Kovalovsky D, Sant'Angelo D, Harty JT, Vukmanovic S. Adaptable TCR avidity thresholds for negative selection. J. Immunol. 181: 6770-6778 (2008). *

• Stordeur P. Monitoring the immune response using real-time PCR. Methods Mol. Biol. 496: 323-338 (2009).

• Stratis A, Pasparakis M, Rupec RA, Markur D, Hartmann K, Scharffetter-Kochanek K, Peters T, van Rooijen N, Krieg T, Haase I. Pathogenic role for skin macrophages in a mouse model of keratinocyte-induced psoriasis-like skin inflammation. J. Clin. Invest. 116: 2094-2104 (2006). *

• Straumann A. Eosinophilic esophagitis: a novel entity? Schweiz. Rundsch. Med. Prax. 95: 191-195 (2006).

• Strobel S, Mowat AM. Oral tolerance and allergic responses to food proteins. Curr. Opin. Allergy Clin. Immunol. 6: 207-213 (2006).

• Stromnes IM, Goverman JM. Passive induction of experimental allergic encephalomyelitis. Nat. Protoc. 1: 1952-1960 (2006). *

• Stromnes IM, Goverman JM. Active induction of experimental allergic encephalomyelitis. Nat. Protoc. 1: 1810-1819 (2006). *

• Stuby U, Biesenbach G, Pieringer H. Administration of infliximab in general practitioners' offices is safe. Clin. Rheumatol. 26: 1863-1866 (2007). *

• Su DJ, Zhang XM, Sui H, Lu FZ, Jin LH, Zhang J. Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population. BMC Med. Genet. 9: 82 (2008). *

• Su W, Hall BJ 4th, Cockerell CJ. Photodermatitis with minimal inflammatory infiltrate: clinical inflammatory conditions with discordant histologic findings. Am. J. Dermatopathol. 28: 482-485 (2006).

• Sugimoto T, Ishikawa Y, Yoshimoto T, Hayashi N, Fujimoto J, Nakanishi K. Interleukin 18 acts on memory T helper cells type 1 to induce airway inflammation and hyperresponsiveness in a naive host mouse. J. Exp. Med. 199: 535-545 (2004). *

• Sullivan BM, Locksley RM. Basophils: a nonredundant contributor to host immunity. Immunity 30: 12-20 (2009). *

• Sumi T, Fukushima A, Fukuda K, Kumagai N, Nishida T, Yagita H, Ueno H. Differential contributions of B7-1 and B7-2 to the development of murine experimental allergic conjunctivitis. Immunol. Lett. 108: 62-67 (2007).

• Sumi T, Ishida W, Ojima A, Kajisako M, Sakanishi T, Yagita H, Fukushima A. CD27 and CD70 do not play a critical role in the development of experimental allergic conjunctivitis in mice. Immunol. Lett. 119: 91-96 (2008).

• Sun J, Sukhova GK, Wolters PJ, Yang M, Kitamoto S, Libby P, Macfarlane LA, Clair JM, Shi GP. Mast cells promote atherosclerosis by releasing proinflammatory cytokines. Nat. Med. 13: 719-724 (2007). *

• Sun JB, Czerkinsky C, Holmgren J. Mucosally induced immunological tolerance, regulatory T cells and the adjuvant effect by cholera toxin B subunit. Scand. J. Immunol. 71: 1-11 (2010). *

• Suskovic S. COPD is not COPD is not allergy. Wien. Klin. Wochenschr. 121: 289-292 (2009).

• Suzuki S, Kokubu F, Kawaguchi M, Homma T, Odaka M, Watanabe S, Ieki K, Matsukura S, Kurokawa M, Takeuchi H, Sasaki Y, Huang SK, Adachi M, Ota H. Expression of interleukin-17F in a mouse model of allergic asthma. Int. Arch. Allergy Immunol. 143 Suppl. 1: 89-94 (2007).

• Svacina S. Metabolic PPAR receptors and skin. Vnitr. Lek. 52: 451-453 (2006).

• Swaidani S, Bulek K, Kang Z, Liu C, Lu Y, Yin W, Aronica M, Li X. The critical role of epithelial-derived Act1 in IL-17- and IL-25-mediated pulmonary inflammation. J. Immunol. 182: 1631-1640 (2009).

• Swynghedauw B. Evolutionary medicine an introduction. Evolutionary biology, a missing element in medical teaching. Bull. Acad. Natl. Med. 193: 1147-1164 (2009).

• Szabo SJ, Sullivan BM, Peng SL, Glimcher LH. Molecular mechanisms regulating Th1 immune responses. Annu. Rev. Immunol. 21: 713-758 (2003). *

• Szczepanik M. Skin-induced tolerance and its reversal by Toll-like receptor ligands. Arch. Immunol. Ther. Exp. (Warsz.) 55: 161-172 (2007).

• Szczepankiewicz A, Breborowicz A, Skibinska M, Wilkosc M, Tomaszewska M, Hauser J. Association analysis of tyrosine kinase FYN gene polymorphisms in asthmatic children. Int. Arch. Allergy Immunol. 145: 43-47 (2007).

• Szczepankiewicz A, Breborowicz A, Sobkowiak P, Popiel A. Are genes associated with energy metabolism important in asthma and BMI? J. Asthma 46: 53-58 (2009).

• Szenborn L, Czajka H, Wysocki J. Controversies around vaccinations. Przegl. Lek. 66: 65-71 (2009).

• t Hart BA, Hintzen RQ, Laman JD. Preclinical assessment of therapeutic antibodies against human CD40 and human interleukin-12/23p40 in a nonhuman primate model of multiple sclerosis. Neurodegener. Dis. 5: 38-52 (2008).

• Taams LS, Palmer DB, Akbar AN, Robinson DS, Brown Z, Hawrylowicz CM. Regulatory T cells in human disease and their potential for therapeutic manipulation. Immunology 118: 1-9 (2006). *

• Tabuchi A, Kuebler WM. Endothelium-platelet interactions in inflammatory lung disease. Vascul. Pharmacol. 49: 141-150 (2008).

• Tachdjian R, Mathias C, Al Khatib S, Bryce PJ, Kim HS, Blaeser F, O'Connor BD, Rzymkiewicz D, Chen A, Holtzman MJ, Hershey GK, Garn H, Harb H, Renz H, Oettgen HC, Chatila TA. Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. J. Exp. Med. 206: 2191-2204 (2009). *

• Tachibana M, Wada K, Katayama K, Kamisaki Y, Maeyama K, Kadowaki T, Blumberg RS, Nakajima A. Activation of peroxisome proliferator-activated receptor gamma suppresses mast cell maturation involved in allergic diseases. Allergy 63: 1136-1147 (2008). *

• Tagen M, Elorza A, Kempuraj D, Boucher W, Kepley CL, Shirihai OS, Theoharides TC. Mitochondrial uncoupling protein 2 inhibits mast cell activation and reduces histamine content. J. Immunol. 183: 6313-6319 (2009).

• Tahara H, Kusuhara H, Maeda K, Koepsell H, Fuse E, Sugiyama Y. Inhibition of OAT3-mediated renal uptake as a mechanism for drug-drug interaction between fexofenadine and probenecid. Drug Metab. Dispos. 34: 743-747 (2006). *

• Tahvanainen J, Kallonen T, Lahteenmaki H, Heiskanen KM, Westermarck J, Rao KV, Lahesmaa R. PRELI is a mitochondrial regulator of human primary T helper cell apoptosis, STAT6 and Th2 cell differentiation. Blood 113: 1268-1277 (2009). *

• Tai YG, Liu JD, Lin KY, Chang JG, Wang CK, Siauw CP, Chen PH. Eosinophilic gastroenteritis with eosinophilic ascites: report of a case. J. Formos. Med. Assoc. 89: 901-904 (1990).

• Takabe K, Paugh SW, Milstien S, Spiegel S. "Inside-out" signaling of sphingosine-1-phosphate: therapeutic targets. Pharmacol. Rev. 60: 181-195 (2008). *

• Takahashi N, Akahoshi M, Matsuda A, Ebe K, Inomata N, Obara K, Hirota T, Nakashima K, Shimizu M, Tamari M, Doi S, Miyatake A, Enomoto T, Nakashima H, Ikezawa Z, Shirakawa T. Association of the IL12RB1 promoter polymorphisms with increased risk of atopic dermatitis and other allergic phenotypes. Hum. Mol. Genet. 14: 3149-3159 (2005). *

• Takahashi N, Kitazawa H, Iwabuchi N, Xiao JZ, Miyaji K, Iwatsuki K, Saito T. Immunostimulatory oligodeoxynucleotide from Bifidobacterium longum suppresses Th2 immune responses in a murine model. Clin. Exp. Immunol. 145: 130-138 (2006). *

• Takayama N, Igarashi O, Kweon MN, Kiyono H. Regulatory role of Peyer's patches for the inhibition of OVA-induced allergic diarrhea. Clin. Immunol. 123: 199-208 (2007). *

• Takeda K, Gelfand EW. Mouse models of allergic diseases. Curr. Opin. Immunol. 21: 660-665 (2009).

• Takemoto CM, Lee YN, Jegga AG, Zablocki D, Brandal S, Shahlaee A, Huang S, Ye Y, Gowrisankar S, Huynh J, McDevitt MA. Mast cell transcriptional networks. Blood Cells Mol. Dis. 41: 82-90 (2008). *

• Takizawa R, Pawankar R, Yamagishi S, Takenaka H, Yagi T. Increased expression of HLA-DR and CD86 in nasal epithelial cells in allergic rhinitics: antigen presentation to T cells and up-regulation by diesel exhaust particles. Clin. Exp. Allergy 37: 420-433 (2007). *

• Talley NJ. Gut eosinophilia in food allergy and systemic and autoimmune diseases. Gastroenterol. Clin. North Am. 37: 307-332 (2008).

• Tamachi T, Maezawa Y, Ikeda K, Iwamoto I, Nakajima H. Interleukin 25 in allergic airway inflammation. Int. Arch. Allergy Immunol. 140 Suppl. 1: 59-62 (2006).

• Tamer L, Calikoglu M, Aras Ates N, Yildirim H, Karakas S, Atik U. Relationship between N-acetyl transferase-2 gene polymorphism and risk of bronchial asthma. Tuberk. Toraks. 54: 137-143 (2006).

• Tan AM, Chen HC, Pochard P, Eisenbarth SC, Herrick CA, Bottomly HK. TLR4 signaling in stromal cells is critical for the initiation of allergic Th2 responses to inhaled antigen. J. Immunol. Mar 1 [Epub ahead of print] (2010).

• Tanabe S. IgE-binding abilities of pentapeptides, QQPFP and PQQPF, in wheat gliadin. J. Nutr. Sci. Vitaminol. (Tokyo) 50: 367-370 (2004).

• Tanabe S, Hochi S. Oral administration of a galactooligosaccharide preparation inhibits development of atopic dermatitis-like skin lesions in NC/Nga mice. Int. J. Mol. Med. 25: 331-336 (2010).

• Tanaka G, Kanaji S, Hirano A, Arima K, Shinagawa A, Goda C, Yasunaga S, Ikizawa K, Yanagihara Y, Kubo M, Kuriyama-Fujii Y, Sugita Y, Inokuchi A, Izuhara K. Induction and activation of the aryl hydrocarbon receptor by IL-4 in B cells. Int. Immunol. 17: 797-805 (2005). *

• Tanaka J, Saga K, Kido M, Nishiura H, Akamatsu T, Chiba T, Watanabe N. Proinflammatory Th2 cytokines induce production of thymic stromal lymphopoietin in human colonic epithelial cells. Dig. Dis. Sci. Sep 16 [Epub ahead of print] (2009). *

• Tanaka J, Watanabe N, Kido M, Saga K, Akamatsu T, Nishio A, Chiba T. Human TSLP and TLR3 ligands promote differentiation of Th17 cells with a central memory phenotype under Th2-polarizing conditions. Clin. Exp. Allergy 39: 89-100 (2009). *

• Tanaka Y. Immunosuppressive effects of glucocoriticoid. Nippon Rinsho 66: 83-88 (2008).

• Tanaka Y, Hamano S, Gotoh K, Murata Y, Kunisaki Y, Nishikimi A, Takii R, Kawaguchi M, Inayoshi A, Masuko S, Himeno K, Sasazuki T, Fukui Y. T helper type 2 differentiation and intracellular trafficking of the interleukin 4 receptor-alpha subunit controlled by the Rac activator Dock2. Nat. Immunol. 8: 1067-1075 (2007). *

• Tanis AA. Azathioprine in inflammatory bowel disease, a safe alternative? Mediators Inflamm. 7: 141-144 (1998). *

• Tannock GW. The search for disease-associated compositional shifts in bowel bacterial communities of humans. Trends Microbiol. 16: 488-495 (2008). *

• Tarzi M, Klunker S, Texier C, Verhoef A, Stapel SO, Akdis CA, Maillere B, Kay AB, Larche M. Induction of interleukin-10 and suppressor of cytokine signalling-3 gene expression following peptide immunotherapy. Clin. Exp. Allergy 36: 465-474 (2006). *

• Tas SW, Vervoordeldonk MJ, Tak PP. Gene therapy targeting nuclear factor-kappaB: towards clinical application in inflammatory diseases and cancer. Curr. Gene Ther. 9: 160-170 (2009).

• Taylor A, Hale J, Wiltschut J, Lehmann H, Dunstan JA, Prescott SL. Evaluation of the effects of probiotic supplementation from the neonatal period on innate immune development in infancy. Clin. Exp. Allergy 36: 1218-1226 (2006). *

• Taylor A, Verhagen J, Akdis CA, Akdis M. T regulatory cells in allergy and health: a question of allergen specificity and balance. Int. Arch. Allergy Immunol. 135: 73-82 (2004).

• Taylor RC, Richmond P, Upham JW. Toll-like receptor 2 ligands inhibit T(H)2 responses to mite allergen. J. Allergy Clin. Immunol. 117: 1148-1154 (2006). *

• Tedeschi A, Cottini M, Asero R. Simultaneous occurrence of chronic autoimmune urticaria and non-allergic asthma: a common mechanism? Eur. Ann. Allergy Clin. Immunol. 41: 56-59 (2009).

• Tella R, Gaig P, Lombardero M, Garcia-Ortega P, Bartra J, Papo M, Batlle X. Allergic eosinophilic gastroenteritis in a child with Crohn's disease. J. Investig. Allergol. Clin. Immunol. 14: 159-161 (2004).

• Terheggen G, Lanyi B, Schanz S, Hoffmann RM, Bohm SK, Leifeld L, Pohl C, Kruis W. Safety, feasibility, and tolerability of ileocolonoscopy in inflammatory bowel disease. Endoscopy 40: 656-663 (2008).

• Teshima R, Amano F, Nakamura R, Tanaka Y, Sawada J. Effects of polyunsaturated fatty acids on calcium response and degranulation from RBL-2H3 cells. Int. Immunopharmacol. 7: 205-210 (2007).

• Teuscher C, Noubade R, Spach K, McElvany B, Bunn JY, Fillmore PD, Zachary JF, Blankenhorn EP. Evidence that the Y chromosome influences autoimmune disease in male and female mice. Proc. Natl. Acad. Sci. U.S.A. 103: 8024-8029 (2006). *

• Teuscher C, Subramanian M, Noubade R, Gao JF, Offner H, Zachary JF, Blankenhorn EP. Central histamine H3 receptor signaling negatively regulates susceptibility to autoimmune inflammatory disease of the CNS. Proc. Natl. Acad. Sci. U.S.A. 104: 10146-10151 (2007). *

• Thayu M, Mamula P. Treatment of iron deficiency anemia in pediatric inflammatory bowel disease. Curr. Treat. Options Gastroenterol. 8: 411-417 (2005).

• Theoharides TC, Kalogeromitros D. The critical role of mast cells in allergy and inflammation. Ann. N. Y. Acad. Sci. 1088: 78-99 (2006). *

• Theoharides TC, Kempuraj D, Iliopoulou BP. Mast cells, T cells, and inhibition by luteolin: implications for the pathogenesis and treatment of multiple sclerosis. Adv. Exp. Med. Biol. 601: 423-430 (2007).

• Theoharides TC, Kempuraj D, Kourelis T, Manola A. Human mast cells stimulate activated T cells. Ann. N. Y. Acad. Sci. 1144: 74-82 (2008). *

• Theoharides TC, Kempuraj D, Tagen M, Conti P, Kalogeromitros D. Differential release of mast cell mediators and the pathogenesis of inflammation. Immunol. Rev. 217: 65-78 (2007). *

• Theoharides TC, Konstantinidou A. Corticotropin-releasing hormone and the blood-brain-barrier. Front. Biosci. 12: 1615-1628 (2007).

• Thia LP, Balfour Lynn IM. Diagnosing allergic bronchopulmonary aspergillosis in children with cystic fibrosis. Paediatr. Respir. Rev. 10: 37-42 (2009).

• Thio M, Blokhuis BR, Nijkamp FP, Redegeld FA. Free immunoglobulin light chains: a novel target in the therapy of inflammatory diseases. Trends Pharmacol. Sci. 29: 170-174 (2008). *

• Thivierge M, Stankova J, Rola-Pleszczynski M. Toll-like receptor agonists differentially regulate cysteinyl-leukotriene receptor 1 expression and function in human dendritic cells. J. Allergy Clin. Immunol. 117: 1155-1162 (2006). *

• Thompson EA, Mathie RT, Baitson ES, Barron SJ, Berkovitz SR, Brands M, Fisher P, Kirby TM, Leckridge RW, Mercer SW, Nielsen HJ, Ratsey DH, Reilly D, Roniger H, Whitmarsh TE. Towards standard setting for patient-reported outcomes in the NHS homeopathic hospitals. Homeopathy 97: 114-121 (2008).

• Thompson-Chagoyan OC, Maldonado J, Gil A. Colonization and impact of disease and other factors on intestinal microbiota. Dig. Dis. Sci. 52: 2069-2077 (2007). *

• Thonhofer R, Soleiman A, Kriessmayr M, Thonhofer U, Wipfler E, Gaugg M, Eder S, Erlacher L. Decrease of proteinuria in a patient with adult-onset Still's disease and glomerulonephritis after anti-TNFalpha therapy. Scand. J. Rheumatol. 35: 485-488 (2006).

• Thrower SL, James L, Hall W, Green KM, Arif S, Allen JS, Van-Krinks C, Lozanoska-Ochser B, Marquesini L, Brown S, Wong FS, Dayan CM, Peakman M. Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man phase I safety study. Clin. Exp. Immunol. 155: 156-165 (2009). *

• Tierney BC, Martin SW, Franzke LH, Marano N, Reissman DB, Louchart RD, Goff JA, Rosenstein NE, Sever JL, McNeil MM; Centers for Disease Control and Prevention's Anthrax Vaccine and Antimicrobial Availability Program. Serious adverse events among participants in the Centers for Disease Control and Prevention's Anthrax Vaccine and Antimicrobial Availability Program for persons at risk for bioterrorism-related inhalational anthrax. Clin. Infect. Dis. 37: 905-911 (2003). *

• Tilg H, Kaser A. Type I interferons and their therapeutic role in Th2-regulated inflammatory disorders. Expert Opin. Biol. Ther. 4: 469-481 (2004).

• Tilley SL, Jaradat M, Stapleton C, Dixon D, Hua X, Erikson CJ, McCaskill JG, Chason KD, Liao G, Jania L, Koller BH, Jetten AM. Retinoid-related orphan receptor gamma controls immunoglobulin production and Th1/Th2 cytokine balance in the adaptive immune response to allergen. J. Immunol. 178: 3208-3218 (2007). *

• Tomiyama S. Immuno-pathogenesis in Meniere's disease. J. Nippon Med. Sch. 70: 212-218 (2003).

• Tonnel AB, Tillie-Leblond I. Refractory asthma: diagnosing allergic bronchopulmonary aspergillosis. Presse. Med. 37: 161-166 (2008).

• Toosi S, Bystryn JC. Potential role of interleukin-17 in the pathogenesis of bullous pemphigoid. Med. Hypotheses Nov 27 [Epub ahead of print] (2009).

• Torgerson TR, Linane A, Moes N, Anover S, Mateo V, Rieux-Laucat F, Hermine O, Vijay S, Gambineri E, Cerf-Bensussan N, Fischer A, Ochs HD, Goulet O, Ruemmele FM. Severe food allergy as a variant of IPEX syndrome caused by a deletion in a noncoding region of the FOXP3 gene. Gastroenterology 132: 1705-1717 (2007). *

• Torii Y, Ito T, Amakawa R, Sugimoto H, Amuro H, Tanijiri T, Katashiba Y, Ogata M, Yokoi T, Fukuhara S. Imidazoquinoline acts as immune adjuvant for functional alteration of thymic stromal lymphopoietin-mediated allergic T cell response. J. Immunol. 181: 5340-5349 (2008). *

• Trakatelli C, Frydas S, Hatzistilianou M, Papadopoulos E, Simeonidou I, Founta A, Paludi D, Petrarca C, Castellani ML, Papaioannou N, Salini V, Conti P, Kempuraj D, Vecchiet J. Chemokines as markers for parasite-induced inflammation and tumors. Int. J. Biol. Markers 20: 197-203 (2005).

• Tran DQ, Shevach EM. Therapeutic potential of FOXP3(+) regulatory T cells and their interactions with dendritic cells. Hum. Immunol. 70: 294-299 (2009).

• Triester SL, Douglas DD. Development of macro-aspartate aminotransferase in a patient undergoing specific allergen injection immunotherapy. Am. J. Gastroenterol. 100: 243-245 (2005). *

• Triggiani M, Giannattasio G, Calabrese C, Loffredo S, Granata F, Fiorello A, Santini M, Gelb MH, Marone G. Lung mast cells are a source of secreted phospholipases A2. J. Allergy Clin. Immunol. 124: 558-565.e1-e3 (2009). *

• Triggiani M, Granata F, Frattini A, Marone G. Activation of human inflammatory cells by secreted phospholipases A2. Biochim. Biophys. Acta 1761: 1289-1300 (2006). *

• Triggiani M, Granata F, Giannattasio G, Marone G. Secretory phospholipases A(2) in inflammatory and allergic diseases: not just enzymes. J. Allergy Clin. Immunol. 116: 1000-1006 (2005). *

• Triggiani M, Granata F, Petraroli A, Loffredo S, Frattini A, Staiano RI, Monaco G, Marone G. Inhibition of secretory phospholipase A(2)-induced cytokine production in human lung macrophages by budesonide. Int. Arch. Allergy Immunol. 150: 144-155 (2009).

• Tripathi A, Lammers KM, Goldblum S, Shea-Donohue T, Netzel-Arnett S, Buzza MS, Antalis TM, Vogel SN, Zhao A, Yang S, Arrietta MC, Meddings JB, Fasano A. Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2. Proc. Natl. Acad. Sci. U.S.A. 106: 16799-16804 (2009). *

• Trivedi SG, Newson J, Rajakariar R, Jacques TS, Hannon R, Kanaoka Y, Eguchi N, Colville-Nash P, Gilroy DW. Essential role for hematopoietic prostaglandin D2 synthase in the control of delayed type hypersensitivity. Proc. Natl. Acad. Sci. U.S.A. 103: 5179-5184 (2006). *

• Trompette A, Divanovic S, Visintin A, Blanchard C, Hegde RS, Madan R, Thorne PS, Wills-Karp M, Gioannini TL, Weiss JP, Karp CL. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 457: 585-588 (2009). *

• Trujillo-Vargas CM, Werner-Klein M, Wohlleben G, Polte T, Hansen G, Ehlers S, Erb KJ. Helminth derived products inhibit the development of allergic responses in mice. Am. J. Respir. Crit. Care Med. 175: 336-344 (2007). *

• Truong W, Shapiro AM. The TIM family of cosignaling receptors: emerging targets for the regulation of autoimmune disease and transplantation tolerance. Cell. Transplant. 16: 977-986 (2008).

• Trzonkowski P, Szarynska M, Mysliwska J, Mysliwski A. Ex vivo expansion of CD4(+)CD25(+) T regulatory cells for immunosuppressive therapy. Cytometry A. 75A: 175-188 (2009).

• Tsai YC, Chang HW, Chang TT, Lee MS, Chu YT, Hung CH. Effects of all-trans retinoic acid on Th1- and Th2-related chemokines production in monocytes. Inflammation 31: 428-433 (2008). *

• Tsai YG, Chiou YL, Chien JW, Wu HP, Lin CY. Induction of IL-10+ CD4+ CD25+ regulatory T cells with decreased NF-kappaB expression during immunotherapy. Pediatr. Allergy Immunol. Aug 13 [Epub ahead of print] (2009). *

• Tse K, Horner AA. Defining a role for ambient TLR ligand exposures in the genesis and prevention of allergic diseases. Semin. Immunopathol. 30: 53-62 (2008). *

• Tse K, Horner AA. Update on Toll-like receptor-directed therapies for human disease. Ann. Rheum. Dis. 66 Suppl. 3: iii77-iii80 (2007).

• Tsimmerman IaS. Helicobacter pylori infection: extragastric effects and diseases (a critical analysis). Klin. Med. (Mosk.) 84: 63-67 (2006).

• Tsutsui H, Adachi K, Seki E, Nakanishi K. Cytokine-induced inflammatory liver injuries. Curr. Mol. Med. 3: 545-559 (2003).

• Tug E, Ozbey U, Tug T, Yuce H. Relationship between the IL-12B promoter polymorphism and allergic rhinitis, familial asthma, serum total IgE, and eosinophil level in asthma patients. J. Investig. Allergol. Clin. Immunol. 19: 21-26 (2009). *

• Turcanu V, Winterbotham M, Kelleher P, Lack G. Peanut-specific B and T cell responses are correlated in peanut-allergic but not in non-allergic individuals. Clin. Exp. Allergy 38: 1132-1139 (2008). *

• Turkcapar N, Kinikli G, Sak SD, Duman M. Specific immunotherapy-induced Sjogren's syndrome. Rheumatol. Int. 26: 182-184 (2005). *

• Turpeinen AM, Ylonen N, von Willebrand E, Basu S, Aro A. Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy. Br. J. Nutr. 100: 112-119 (2008). *

• Turunen U, Elomaa I, Anttila VJ, Seppala K. Mesalazine tolerance in patients with inflammatory bowel disease and previous intolerance or allergy to sulphasalazine or sulphonamides. Scand. J. Gastroenterol. 22: 798-802 (1987).

• Tutaj M, Szczepanik M. Mechanisms involved in the regulation of immune response in experimental autoimmune encephalomyelitis in mice. Postepy. Hig. Med. Dosw. (Online) 60: 571-583 (2006).

• Tzanakis NE, Tsiligianni IG, Siafakas NM. Pulmonary involvement and allergic disorders in inflammatory bowel disease. World J. Gastroenterol. 16: 299-305 (2010). *

• Uchiyama-Tanaka Y, Mori Y, Kimura T, Sonomura K, Umemura S, Kishimoto N, Nose A, Tokoro T, Kijima Y, Yamahara H, Nagata T, Masaki H, Umeda Y, Okazaki K, Iwasaka T. Acute tubulointerstitial nephritis associated with autoimmune-related pancreatitis. Am. J. Kidney Dis. 43: e18-e25 (2004).

• Ueda H, Yamazaki C, Yamazaki M. A hydroxyl group of flavonoids affects oral anti-inflammatory activity and inhibition of systemic tumor necrosis factor-alpha production. Biosci. Biotechnol. Biochem. 68: 119-125 (2004). *

• Ueki S, Kato H, Takeda M, Ito W, Fujita M, Kayaba H, Chihara J. Cross-talk between arteriosclerotic diseases and allergic inflammation. Rinsho Byori 56: 1107-1111 (2008).

• Ueki S, Mahemuti G, Oyamada H, Kato H, Kihara J, Tanabe M, Ito W, Chiba T, Takeda M, Kayaba H, Chihara J. Retinoic acids are potent inhibitors of spontaneous human eosinophil apoptosis. J. Immunol. 181: 7689-7698 (2008). *

• Uetrecht J. Immunoallergic drug-induced liver injury in humans. Semin. Liver Dis. 29: 383-392 (2009).

• Ulbricht C, Basch E, Szapary P, Hammerness P, Axentsev S, Boon H, Kroll D, Garraway L, Vora M, Woods J; Natural Standard Research Collaboration. Guggul for hyperlipidemia: a review by the Natural Standard Research Collaboration. Complement. Ther. Med. 13: 279-290 (2005).

• Um JY, Do KR, Hwang WJ, Shin TY, Hwang CY, Kim CH, Kim YK, Hong SH, Kim HM. Interleukin-1 beta gene polymorphism related with allergic pathogenesis in iris constitution. Immunopharmacol. Immunotoxicol. 26: 653-661 (2004).

• Umemura T, Katsuyama Y, Hamano H, Kitahara K, Takayama M, Arakura N, Kawa S, Tanaka E, Ota M. Association analysis of Toll-like receptor 4 polymorphisms with autoimmune pancreatitis. Hum. Immunol. 70: 742-746 (2009).

• Umetsu DT, Dekruyff RH. The regulation of allergy and asthma. Immunol. Rev. 212: 238-255 (2006). *

• Urschel S, Kayikci L, Wintergerst U, Notheis G, Jansson A, Belohradsky BH. Common variable immunodeficiency disorders in children: delayed diagnosis despite typical clinical presentation. J. Pediatr. 154: 888-894 (2009). *

• Usui M, Isaji S, Mizuno S, Sakurai H, Uemoto S. Experiences and problems pre-operative anti-CD20 monoclonal antibody infusion therapy with splenectomy and plasma exchange for ABO-incompatible living-donor liver transplantation. Clin. Transplant. 21: 24-31 (2007). *

• Valdez PA, Wang H, Seshasayee D, van Lookeren Campagne M, Gurney A, Lee WP, Grewal IS. NTB-A, a new activating receptor in T cells that regulates autoimmune disease. J. Biol. Chem. 279: 18662-18669 (2004). *

• Valdivia G. Epidemiological transition: the other side of the coin. Rev. Med. Chil. 134: 675-678 (2006).

• Valenta R. The future of antigen-specific immunotherapy of allergy. Nat. Rev. Immunol. 2: 446-453 (2002). *

• Valenta R, Mittermann I, Werfel T, Garn H, Renz H. Linking allergy to autoimmune disease. Trends Immunol. 30: 109-116 (2009). *

• van Beelen AJ, Teunissen MB, Kapsenberg ML, de Jong EC. Interleukin-17 in inflammatory skin disorders. Curr. Opin. Allergy Clin. Immunol. 7: 374-381 (2007). *

• Van Bekkum DW. Preclinical experiments. Best Pract. Res. Clin. Haematol. 17: 201-222 (2004).

• Van Bodegraven AA, Pena AS. Treatment of extraintestinal manifestations in inflammatory bowel disease. Curr. Treat. Options Gastroenterol. 6: 201-212 (2003).

• Van De Merwe JP, Yamada T, Sakamoto Y. Systemic aspects of interstitial cystitis, immunology and linkage with autoimmune disorders. Int. J. Urol. 10 Suppl. 1: S35-S38 (2003).

• van der Ent CK, Hoekstra H, Rijkers GT. Successful treatment of allergic bronchopulmonary aspergillosis with recombinant anti-IgE antibody. Thorax 62: 276-277 (2007). *

• van der Pouw Kraan TC, Kucukaycan M, Bakker AM, Baggen JM, van der Zee JS, Dentener MA, Wouters EF, Verweij CL. Chronic obstructive pulmonary disease is associated with the -1055 IL-13 promoter polymorphism. Genes Immun. 3: 436-439 (2002). *

• van Die I, Cummings RD. Glycans modulate immune responses in helminth infections and allergy. Chem. Immunol. Allergy 90: 91-112 (2006).

• van Duin D, Shaw AC. Toll-like receptors in older adults. J. Am. Geriatr. Soc. 55: 1438-1444 (2007).

• van Hogezand RA, Verspaget HW. New therapies for inflammatory bowel disease: an update on chimeric anti-TNF alpha antibodies and IL-10 therapy. Scand. J. Gastroenterol. Suppl. 223: 105-107 (1997).

• van Ledden-Klok MJ, Fiselier TJ, Draaisma JM. A boy with Churg-Strauss syndrome and thrombosis associated with eosinophilia. Ned. Tijdschr. Geneeskd. 150: 913-917 (2006).

• Van Limbergen J, Russell RK, Nimmo ER, Zhao Y, Liao H, Drummond HE, Davies G, Gillett PM, McGrogan P, Bisset WM, Mahdi G, Wilson DC, Brown SJ, McLean WH, Satsangi J. Filaggrin loss-of-function variants are associated with atopic comorbidity in pediatric inflammatory bowel disease. Inflamm. Bowel Dis. 15: 1492-1498 (2009).

• van Odijk J, Kull I, Borres MP, Brandtzaeg P, Edberg U, Hanson LA, Host A, Kuitunen M, Olsen SF, Skerfving S, Sundell J, Wille S. Breastfeeding and allergic disease: a multidisciplinary review of the literature (1966-2001) on the mode of early feeding in infancy and its impact on later atopic manifestations. Allergy 58: 833-843 (2003). *

• van Oosterhout AJ, Bloksma N. Regulatory T-lymphocytes in asthma. Eur. Respir. J. 26: 918-932 (2005). *

• van Oosterhout AJ, Deurloo DT, Groot PC. Cytotoxic T lymphocyte antigen 4 polymorphisms and allergic asthma. Clin. Exp. Allergy 34: 4-8 (2004).

• Van Pelt FN, Carey MA, Carey JB. Chapter 29. Acute and chronic liver diseases induced by drugs or xenobiotics. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 375-388 (2007). *

• van Ree R, Yazdanbakhsh M. Allergic disorders in African countries: linking immunology to accurate phenotype. Allergy 62: 237-246 (2007). *

• van Wijk F, Hoeks S, Nierkens S, Koppelman SJ, van Kooten P, Boon L, Knippels LM, Pieters R. CTLA-4 signaling regulates the intensity of hypersensitivity responses to food antigens, but is not decisive in the induction of sensitization. J. Immunol. 174: 174-179 (2005). *

• van Wijk F, Nierkens S, de Jong W, Wehrens EJ, Boon L, van Kooten P, Knippels LM, Pieters R. The CD28/CTLA-4-B7 signaling pathway is involved in both allergic sensitization and tolerance induction to orally administered peanut proteins. J. Immunol. 178: 6894-6900 (2007). *

• van Wijk F, Wehrens EJ, Nierkens S, Boon L, Kasran A, Pieters R, Knippels LM. CD4(+)CD25(+) T cells regulate the intensity of hypersensitivity responses to peanut, but are not decisive in the induction of oral sensitization. Clin. Exp. Allergy 37: 572-581 (2007). *

• VanAmerongen BM, Dijkstra CD, Lips P, Polman CH. Multiple sclerosis and vitamin D: an update. Eur. J. Clin. Nutr. 58: 1095-1109 (2004). *

• Vandenbulcke L, Bachert C, Van Cauwenberge P, Claeys S. The innate immune system and its role in allergic disorders. Int. Arch. Allergy Immunol. 139: 159-165 (2005).

• Vaughan DF, Clay Hodgin E, Hosgood GL, Bernstein JA. Clinical and histopathological features of pemphigus foliaceus with and without eosinophilic infiltrates: a retrospective evaluation of 40 dogs. Vet. Dermatol. Feb 3 [Epub ahead of print] (2010).

• Velasco G, Campo M, Manrique OJ, Bellou A, He H, Arestides RS, Schaub B, Perkins DL, Finn PW. Toll-like receptor 4 or 2 agonists decrease allergic inflammation. Am. J. Respir. Cell. Mol. Biol. 32: 218-224 (2005). *

• Veldhoen M. The role of T helper subsets in autoimmunity and allergy. Curr. Opin. Immunol. 21: 606-611 (2009).

• Venkatraman MS, Chittiboyina A, Meingassner J, Ho CI, Varani J, Ellis CN, Avery MA, Pershadsingh HA, Kurtz TW, Benson SC. alpha-Lipoic acid-based PPARgamma agonists for treating inflammatory skin diseases. Arch. Dermatol. Res. 296: 97-104 (2004). *

• Venken K, Thewissen M, Hellings N, Somers V, Hensen K, Rummens JL, Stinissen P. A CFSE based assay for measuring CD4(+)CD25(+) regulatory T cell mediated suppression of auto-antigen specific and polyclonal T cell responses. J. Immunol. Methods 322: 1-11 (2007). *

• Venturi A, Gionchetti P, Rizzello F, Johansson R, Zucconi E, Brigidi P, Matteuzzi D, Campieri M. Impact on the composition of the faecal flora by a new probiotic preparation: preliminary data on maintenance treatment of patients with ulcerative colitis. Aliment. Pharmacol. Ther. 13: 1103-1108 (1999). *

• Venuprasad K, Elly C, Gao M, Salek-Ardakani S, Harada Y, Luo JL, Yang C, Croft M, Inoue K, Karin M, Liu YC. Convergence of Itch-induced ubiquitination with MEKK1-JNK signaling in Th2 tolerance and airway inflammation. J. Clin. Invest. 116: 1117-1126 (2006). *

• Venuprasad K, Huang H, Harada Y, Elly C, Subramaniam M, Spelsberg T, Su J, Liu YC. The E3 ubiquitin ligase Itch regulates expression of transcription factor Foxp3 and airway inflammation by enhancing the function of transcription factor TIEG1. Nat. Immunol. 9: 245-253 (2008). *

• Vercelli D. Mechanisms of the hygiene hypothesis - molecular and otherwise. Curr. Opin. Immunol. 18: 733-737 (2006).

• Vermaat H, Smienk F, Rustemeyer T, Bruynzeel DP, Kirtschig G. Anogenital allergic contact dermatitis, the role of spices and flavour allergy. Contact Dermatitis 59: 233-237 (2008).

• Vermeire S, Van Assche G, Rutgeerts P. Serum sickness, encephalitis and other complications of anti-cytokine therapy. Best Pract. Res. Clin. Gastroenterol. 23: 101-112 (2009).

• Verstraeten T, Davis R, DeStefano F. Immunity to tetanus is protective against the development of multiple sclerosis. Med. Hypotheses 65: 966-969 (2005).

• Vidal-Gonzalez P, Cervantes-Castro J, Rojas-Reyna GA, Cerda CR, Martinez WK, Levy MT. Sclerosing mesenteritis. Presentation of three cases and review of the literature. Cir. Cir. 76: 337-342 (2008).

• Vilella Puig R. IgE-mediated allergic responses. Arch. Bronconeumol. 42: S6-S12 (2006).

• Villa A, Notarangelo LD, Roifman CM. Omenn syndrome: inflammation in leaky severe combined immunodeficiency. J. Allergy Clin. Immunol. 122: 1082-1086 (2008). *

• Villasenor AG, Kondru R, Ho H, Wang S, Papp E, Shaw D, Barnett JW, Browner MF, Kuglstatter A. Structural insights for design of potent spleen tyrosine kinase inhibitors from crystallographic analysis of three inhibitor complexes. Chem. Biol. Drug Des. 73: 466-470 (2009).

• Virnig C, Bush RK. Allergic bronchopulmonary aspergillosis: a US perspective. Curr. Opin. Pulm. Med. 13: 67-71 (2007).

• Virta M, Pessi T, Helminen M, Seiskari T, Kondrashova A, Knip M, Hyoty H, Hurme M. Interaction between CD14-159C>T polymorphism and Helicobacter pylori is associated with serum total immunoglobulin E. Clin. Exp. Allergy 38: 1929-1934 (2008). *

• Virtanen SM, Kaila M, Pekkanen J, Kenward MG, Uusitalo U, Pietinen P, Kronberg-Kippila C, Hakulinen T, Simell O, Ilonen J, Veijola R, Knip M. Early introduction of oats associated with decreased risk of persistent asthma and early introduction of fish with decreased risk of allergic rhinitis. Br. J. Nutr. 103: 266-273 (2010). *

• Vliagoftis H, Befus AD. Rapidly changing perspectives about mast cells at mucosal surfaces. Immunol. Rev. 206: 190-203 (2005). *

• Voitharou C, Krikorian D, Sakarellos C, Sakarellos-Daitsiotis M, Panou-Pomonis E. A complementary La/SSB epitope anchored to sequential oligopeptide carrier regulates the anti-La/SSB response in immunized animals. J. Pept. Sci. 14: 1069-1076 (2008). *

• Vojdani A, Erde J. Regulatory T cells, a potent immunoregulatory target for CAM researchers: modulating allergic and infectious disease pathology (II). Evid. Based Complement. Alternat. Med. 3: 209-215 (2006). *

• Vojdani A, Lambert J. The role of Th17 in neuroimmune disorders: target for CAM therapy. Part I. Evid. Based Complement. Alternat. Med. Jul 21 [Epub ahead of print] (2009). *

• Vollmert C, Illig T, Altmuller J, Klugbauer S, Loesgen S, Dumitrescu L, Wjst M. Single nucleotide polymorphism screening and association analysis - exclusion of integrin beta 7 and vitamin D receptor (chromosome 12q) as candidate genes for asthma. Clin. Exp. Allergy 34: 1841-1850 (2004). *

• von Bubnoff D, Andres E, Hentges F, Bieber T, Michel T, Zimmer J. Natural killer cells in atopic and autoimmune diseases of the skin. J. Allergy Clin. Immunol. 125: 60-68 (2010). *

• von Bubnoff D, Fimmers R, Bogdanow M, Matz H, Koch S, Bieber T. Asymptomatic atopy is associated with increased indoleamine 2,3-dioxygenase activity and interleukin-10 production during seasonal allergen exposure. Clin. Exp. Allergy 34: 1056-1063 (2004). *

• von Budingen HC, Menge T, Hauser SL, Genain CP. Restrictive and diversifying elements of the anti-myelin/oligodendrocyte glycoprotein antibody response in primate experimental allergic encephalomyelitis. Immunogenetics 58: 122-128 (2006). *

• von Herbay A. Pathological versus clinical differential diagnosis in IBD. Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 65-66. September 12 - 13 (2003). *

• Voulgari PV, Venetsanopoulou AI, Exarchou SA, Alamanos Y, Tsifetaki N, Drosos AA. Sustained clinical response and high infliximab survival in psoriatic arthritis patients: a 3-year long-term study. Semin. Arthritis Rheum. 37: 293-298 (2008). *

• Vroling AB, Jonker MJ, Breit TM, Fokkens WJ, van Drunen CM. Comparison of expression profiles induced by dust mite in airway epithelia reveals a common pathway. Allergy 63: 461-467 (2008). *

• Wadworth AN, Fitton A. Olsalazine. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in inflammatory bowel disease. Drugs 41: 647-664 (1991).

• Waern I, Jonasson S, Hjoberg J, Bucht A, Abrink M, Pejler G, Wernersson S. Mouse mast cell protease 4 is the major chymase in murine airways and has a protective role in allergic airway inflammation. J. Immunol. 183: 6369-6376 (2009).

• Wagner A, Forster-Waldl E, Garner-Spitzer E, Schabussova I, Kundi M, Pollak A, Scheiner O, Joachim A, Wiedermann U. Immunoregulation by Toxoplasma gondii infection prevents allergic immune responses in mice. Int. J. Parasitol. 39: 465-472 (2009). *

• Wagner AH, Wittjen I, Stojanovic T, Middel P, Meingassner JG, Hecker M. Signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. J. Allergy Clin. Immunol. 121: 158-165.e5 (2008). *

• Wakashin H, Hirose K, Iwamoto I, Nakajima H. Role of IL-23-Th17 cell axis in allergic airway inflammation. Int. Arch. Allergy Immunol. 149 Suppl. 1: 108-112 (2009).

• Wakashin H, Hirose K, Maezawa Y, Kagami SI, Suto A, Watanabe N, Saito Y, Hatano M, Tokuhisa T, Iwakura Y, Puccetti P, Iwamoto I, Nakajima H. IL-23 and Th17 cells enhance Th2 cell-mediated eosinophilic airway inflammation in mice. Am. J. Respir. Crit. Care Med. 178: 1023-1032 (2008). *

• Walsh ER, August A. Eosinophils and allergic airway disease: there is more to the story. Trends Immunol. 31: 39-44 (2010). *

• Wambre E, Van Overtvelt L, Maillere B, Humphreys R, von Hofe E, Ferhat L, Ebo D, Moingeon P. Single cell assessment of allergen-specific T cell responses with MHC class II peptide tetramers: methodological aspects. Int. Arch. Allergy Immunol. 146: 99-112 (2008).

• Wang F, Wan L, Zhang C, Zheng X, Li J, Chen ZK. Tim-3-galectin-9 pathway involves the suppression induced by CD4+CD25+ regulatory T cells. Immunobiology 214: 342-349 (2009).

• Wang H, Kess D, Lindqvist AK, Peters T, Sindrilaru A, Wlaschek M, Blakytny R, Holmdahl R, Scharffetter-Kochanek K. A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model. J. Immunol. 180: 5520-5529 (2008). *

• Wang H, Peters T, Kess D, Sindrilaru A, Oreshkova T, Van Rooijen N, Stratis A, Renkl AC, Sunderkotter C, Wlaschek M, Haase I, Scharffetter-Kochanek K. Activated macrophages are essential in a murine model for T cell-mediated chronic psoriasiform skin inflammation. J. Clin. Invest. 116: 2105-2114 (2006). *

• Wang H, Peters T, Sindrilaru A, Kess D, Oreshkova T, Yu XZ, Seier AM, Schreiber H, Wlaschek M, Blakytny R, Rohrbein J, Schulz G, Weiss JM, Scharffetter-Kochanek K. TGF-beta-dependent suppressive function of Tregs requires wild-type levels of CD18 in a mouse model of psoriasis. J. Clin. Invest. 118: 2629-2639 (2008). *

• Wang H, Peters T, Sindrilaru A, Scharffetter-Kochanek K. Key role of macrophages in the pathogenesis of CD18 hypomorphic murine model of psoriasis. J. Invest. Dermatol. 129: 1100-1114 (2009). *

• Wang H, von Rohrscheidt J, Roehrbein J, Peters T, Sindrilaru A, Kess D, Preissner KT, Scharffetter-Kochanek K. Extracellular adherence protein of Staphylococcus aureus suppresses disease by Inhibiting T-cell recruitment in a mouse model of psoriasis. J. Invest. Dermatol. Oct 8 [Epub ahead of print] (2009). *

• Wang JY, Lin CG, Hsiao YH, Liou YH, Wu LS. Single nucleotide polymorphisms and haplotype of MD-1 gene associated with high serum IgE phenotype with mite-sensitive allergy in Taiwanese children. Int. J. Immunogenet. 34: 407-412 (2007). *

• Wang N, Campo M, Ting L, Fleming C, Terhorst C, Finn PW. The costimulatory molecule SLAM is critical for pulmonary allergic responses. Am. J. Respir. Cell. Mol. Biol. 35: 206-210 (2006). *

• Wang XD, Zhang L, Duan H, She WY, Zhao Y, Liu S, Han DM. Association of single nucleotide polymorphisms of GATA3 with allergic rhinitis phenotypes in Chinese. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 43: 494-498 (2008).

• Wang YH, Liu YJ. The IL-17 cytokine family and their role in allergic inflammation. Curr. Opin. Immunol. 20: 697-702 (2008). *

• Wang YH, Liu YJ. Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin. Exp. Allergy 39: 798-806 (2009). *

• Wanich N, Nowak-Wegrzyn A, Sampson HA, Shreffler WG. Allergen-specific basophil suppression associated with clinical tolerance in patients with milk allergy. J. Allergy Clin. Immunol. 123: 789-794.e20 (2009). *

• Warman JI, Korelitz BI, Fleisher MR, Janardhanam R. Cumulative experience with short- and long-term toxicity to 6-mercaptopurine in the treatment of Crohn's disease and ulcerative colitis. J. Clin. Gastroenterol. 37: 220-225 (2003).

• Warstedt K, Furuhjelm C, Duchen K, Falth-Magnusson K, Fageras M. The effects of omega-3 fatty acid supplementation in pregnancy on maternal eicosanoid, cytokine and chemokine secretion. Pediatr. Res. 66: 212-217 (2009).

• Weckmann M, Collison A, Simpson JL, Kopp MV, Wark PA, Smyth MJ, Yagita H, Matthaei KI, Hansbro N, Whitehead B, Gibson PG, Foster PS, Mattes J. Critical link between TRAIL and CCL20 for the activation of T(H)2 cells and the expression of allergic airway disease. Nat. Med. 13: 1308-1315 (2007). *

• Wegmann KW, Wagner CR, Whitham RH, Hinrichs DJ. Synthetic peptide dendrimers block the development and expression of experimental allergic encephalomyelitis. J. Immunol. 181: 3301-3309 (2008). *

• Wei J, Feng J. Relevance of pharmacokinetics and bioavailability of intranasal corticosteroids in allergic rhinitis. Recent Pat. Inflamm. Allergy Drug Discov. Dec 14 [Epub ahead of print] (2009).

• Weidinger S, Gieger C, Rodriguez E, Baurecht H, Mempel M, Klopp N, Gohlke H, Wagenpfeil S, Ollert M, Ring J, Behrendt H, Heinrich J, Novak N, Bieber T, Kramer U, Berdel D, von Berg A, Bauer CP, Herbarth O, Koletzko S, Prokisch H, Mehta D, et al. Genome-wide scan on total serum IgE levels identifies FCER1A as novel susceptibility locus. PLoS Genet. 4: e1000166 (2008). *

• Weidinger S, Klopp N, Rummler L, Wagenpfeil S, Baurecht HJ, Gauger A, Darsow U, Jakob T, Novak N, Schafer T, Heinrich J, Behrendt H, Wichmann HE, Ring J, Illig T; for the KORA study group. Association of CARD15 polymorphisms with atopy-related traits in a population-based cohort of Caucasian adults. Clin. Exp. Allergy 35: 866-872 (2005).

• Weiner HL. Multiple sclerosis is an inflammatory T-cell-mediated autoimmune disease. Arch. Neurol. 61: 1613-1615 (2004). *

• Weiss ST, Litonjua AA. Maternal diet vs lack of exposure to sunlight as the cause of the epidemic of asthma, allergies and other autoimmune diseases. Thorax 62: 745-746 (2007). *

• Wells JW, Choy K, Lloyd CM, Noble A. Suppression of allergic airway inflammation and IgE responses by a class I restricted allergen peptide vaccine. Mucosal Immunol. 2: 54-62 (2009). *

• Wells JW, Cowled CJ, Farzaneh F, Noble A. Combined triggering of dendritic cell receptors results in synergistic activation and potent cytotoxic immunity. J. Immunol. 181: 3422-3431 (2008). *

• Weskamp G, Ford JW, Sturgill J, Martin S, Docherty AJ, Swendeman S, Broadway N, Hartmann D, Saftig P, Umland S, Sehara-Fujisawa A, Black RA, Ludwig A, Becherer JD, Conrad DH, Blobel CP. ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23. Nat. Immunol. 7: 1293-1298 (2006). *

• Westall FC. Comments to: integrating theories of the etiology of Crohn's disease on the etiology of Crohn's disease: questioning the hypotheses. Med. Sci. Monit. 12: LE5-LE6 (2006). *

• Widegren H, Erjefalt J, Korsgren M, Andersson M, Greiff L. Effects of intranasal TNF-alpha on granulocyte recruitment and activity in healthy subjects and patients with allergic rhinitis. Respir. Res. 9: 15 (2008). *

• Wiegard C, Lohse AW. Liver and rheumatism. Z. Rheumatol. 64: 26-31 (2005).

• Wilders MM, Drexhage HA, Kokje M, Verspaget HW, Meuwissen SG. Peripolesis followed by cytotoxicity in chronic idiopathic inflammatory bowel disease. Clin. Exp. Immunol. 57: 614-620 (1984). *

• Willemsen LE, Koetsier MA, Balvers M, Beermann C, Stahl B, van Tol EA. Polyunsaturated fatty acids support epithelial barrier integrity and reduce IL-4 mediated permeability in vitro. Eur. J. Nutr. 47: 183-191 (2008). *

• Willers SM, Devereux G, Craig LC, McNeill G, Wijga AH, Abou El-Magd W, Turner SW, Helms PJ, Seaton A. Maternal food consumption during pregnancy and asthma, respiratory and atopic symptoms in 5-year-old children. Thorax 62: 772-778 (2007). *

• Williams LK, Ownby DR, Maliarik MJ, Johnson CC. The role of endotoxin and its receptors in allergic disease. Ann. Allergy Asthma Immunol. 94: 323-332 (2005).

• Williams MA, Porter M, Horton M, Guo J, Roman J, Williams D, Breysse P, Georas SN. Ambient particulate matter directs nonclassic dendritic cell activation and a mixed TH1/TH2-like cytokine response by naive CD4+ T cells. J. Allergy Clin. Immunol. 119: 488-497 (2007). *

• Willis-Owen SA, Morar N, Willis-Owen CA. Atopic dermatitis: insights from linkage overlap and disease co-morbidity. Expert Rev. Mol. Med. 9: 1-13 (2007).

• Wills-Karp M, Nathan A, Page K, Karp CL. New insights into innate immune mechanisms underlying allergenicity. Mucosal Immunol. Dec 23 [Epub ahead of print] (2009).

• Wills-Karp M, Santeliz J, Karp CL. The germless theory of allergic disease: revisiting the hygiene hypothesis. Nat. Rev. Immunol. 1: 69-75 (2001). *

• Wilson MS, Elnekave E, Mentink-Kane MM, Hodges MG, Pesce JT, Ramalingam TR, Thompson RW, Kamanaka M, Flavell RA, Keane-Myers A, Cheever AW, Wynn TA. IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice. J. Clin. Invest. 117: 2941-2951 (2007). *

• Wilson MS, Maizels RM. Regulatory T cells induced by parasites and the modulation of allergic responses. Chem. Immunol. Allergy 90: 176-195 (2006).

• Wilson MS, Maizels RM. Regulation of allergy and autoimmunity in helminth infection. Clin. Rev. Allergy Immunol. 26: 35-50 (2004). *

• Wilson RH, Whitehead GS, Nakano H, Free ME, Kolls JK, Cook DN. Allergic sensitization through the airway primes Th17-dependent neutrophilia and airway hyperresponsiveness. Am. J. Respir. Crit. Care Med. 180: 720-730 (2009). *

• Wing K, Sakaguchi S. Regulatory T cells as potential immunotherapy in allergy. Curr. Opin. Allergy Clin. Immunol. 6: 482-488 (2006).

• Wisniewski A, Obojski A, Pawlik A, Jasek M, Luszczek W, Majorczyk E, Nowak I, Kusnierczyk P. Polymorphism of the TGFB1 gene is not associated with bronchial allergic asthma in a Polish population. Hum. Immunol. 70: 134-138 (2009).

• Wittke A, Weaver V, Mahon BD, August A, Cantorna MT. Vitamin D receptor-deficient mice fail to develop experimental allergic asthma. J. Immunol. 173: 3432-3246 (2004). *

• Wittmann M, Zeitvogel J, Wang D, Werfel T. IL-27 is expressed in chronic human eczematous skin lesions and stimulates human keratinocytes. J. Allergy Clin. Immunol. 124: 81-89 (2009). *

• Wjst M, Altmuller J, Faus-Kessler T, Braig C, Bahnweg M, Andre E. Asthma families show transmission disequilibrium of gene variants in the vitamin D metabolism and signalling pathway. Respir. Res. 7: 60 (2006). *

• Wjst M, Lichtner P, Meitinger T, Grimbacher B. STAT3 single-nucleotide polymorphisms and STAT3 mutations associated with hyper-IgE syndrome are not responsible for increased serum IgE serum levels in asthma families. Eur. J. Hum. Genet. 17: 352-356 (2009). *

• Wohlleben G, Erb KJ. Immune stimulatory strategies for the prevention and treatment of asthma. Curr. Pharm. Des. 12: 3281-3292 (2006).

• Wolbink GJ, Vis M, Lems W, Voskuyl AE, De Groot E, Nurmohamed MT, Stapel S, Tak PP, Aarden L, Dijkmans B. Development of antiinfliximab antibodies and relationship to clinical response in patients with rheumatoid arthritis. Arthritis Rheum. 54: 711-715 (2006). *

• Wolf R, Orion E, Matz H, Maitra S, Rowland-Payne C. Smoking can be good for you. J. Cosmet. Dermatol. 3: 107-111 (2004).

• Won HY, Min HJ, Ahn JH, Yoo SE, Bae MA, Hong JH, Hwang ES. Anti-allergic function and regulatory mechanisms of KR62980 in allergen-induced airway inflammation. Biochem. Pharmacol. Nov 4 [Epub ahead of print] (2009). *

• Wong BR, Grossbard EB, Payan DG, Masuda ES. Targeting Syk as a treatment for allergic and autoimmune disorders. Expert Opin. Investig. Drugs 13: 743-762 (2004).

• Wong CK, Cao J, Yin YB, Lam CW. IL-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism. Eur. Respir. J. Sep 9 [Epub ahead of print] (2009).

• Wong CK, Cheung PF, Ip WK, Lam CW. Intracellular signaling mechanisms regulating Toll-like receptor-mediated activation of eosinophils. Am. J. Respir. Cell. Mol. Biol. 37: 85-96 (2007). *

• Wong CK, Ho CY, Ko FW, Chan CH, Ho AS, Hui DS, Lam CW. Proinflammatory cytokines (IL-17, IL-6, IL-18 and IL-12) and Th cytokines (IFN-gamma, IL-4, IL-10 and IL-13) in patients with allergic asthma. Clin. Exp. Immunol. 125: 177-183 (2001). *

• Wong CK, Lun SW, Ko FW, Ip WK, Hui DS, Lam CW. Increased expression of plasma and cell surface co-stimulatory molecules CTLA-4, CD28 and CD86 in adult patients with allergic asthma. Clin. Exp. Immunol. 141: 122-129 (2005). *

• Wong CK, Lun SW, Ko FW, Wong PT, Hu SQ, Chan IH, Hui DS, Lam CW. Activation of peripheral Th17 lymphocytes in patients with asthma. Immunol. Invest. 38: 652-664 (2009). *

• Wong SY, Lu CP, Roth DB. A RAG1 mutation found in Omenn syndrome causes coding flank hypersensitivity: a novel mechanism for antigen receptor repertoire restriction. J. Immunol. 181: 4124-4130 (2008). *

• Woodfolk JA. T-cell responses to allergens. J. Allergy Clin. Immunol. 119: 280-294 (2007). *

• Woodward DF, Nieves AL, Friedlaender MH. Characterization of receptor subtypes involved in prostanoid-induced conjunctival pruritus and their role in mediating allergic conjunctival itching. J. Pharmacol. Exp. Ther. 279: 137-142 (1996).

• Woodworth BA, Wood R, Baatz JE, Schlosser RJ. Sinonasal surfactant protein A1, A2, and D gene expression in cystic fibrosis: a preliminary report. Otolaryngol. Head Neck Surg. 137: 34-38 (2007).

• Woschnagg C, Rubin J, Venge P. Eosinophil cationic protein (ECP) is processed during secretion. J. Immunol. 183: 3949-3954 (2009).

• Wozniak KL, Ravi S, Macias S, Young ML, Olszewski MA, Steele C, Wormley FL. Insights into the mechanisms of protective immunity against Cryptococcus neoformans infection using a mouse model of pulmonary cryptococcosis. PLoS One 4: e6854 (2009). *

• Wraith DC. Therapeutic peptide vaccines for treatment of autoimmune diseases. Immunol. Lett. 122: 134-136 (2009).

• Wu K, Bi Y, Sun K, Xia J, Wang Y, Wang C. Suppression of allergic inflammation by allergen-DNA-modified dendritic cells depends on the induction of Foxp3+ Regulatory T cells. Scand. J. Immunol. 67: 140-151 (2008). *

• Wu LS, Tan CY, Wang LM, Lin CG, Wang JY. Variant in promoter region of platelet-derived growth factor receptor-alpha (PDGFRalpha) gene is associated with the severity and allergic status of childhood asthma. Int. Arch. Allergy Immunol. 141: 37-46 (2006).

• Wu TC, Chen PH. Health consequences of nutrition in childhood and early infancy. Pediatr. Neonatol. 50: 135-142 (2009).

• Wu Y, Zheng Z, Jiang Y, Chess L, Jiang H. The specificity of T cell regulation that enables self-nonself discrimination in the periphery. Proc. Natl. Acad. Sci. U.S.A. 106: 534-539 (2009). *

• Wynn T. Cellular and molecular mechanisms of fibrosis. J. Pathol. 214: 199-210 (2008). *

• Wynn TA. IL-13 effector functions. Annu. Rev. Immunol. 21: 425-456 (2003). *

• Xanthakos SA, Schwimmer JB, Melin-Aldana H, Rothenberg ME, Witte DP, Cohen MB. Prevalence and outcome of allergic colitis in healthy infants with rectal bleeding: a prospective cohort study. J. Pediatr. Gastroenterol. Nutr. 41: 16-22 (2005). *

• Xia ZW, Zhong WW, Xu LQ, Sun JL, Shen QX, Wang JG, Shao J, Li YZ, Yu SC. Heme oxygenase-1-mediated CD4+CD25high regulatory T cells suppress allergic airway inflammation. J. Immunol. 177: 5936-5945 (2006). *

• Xiang YY, Wang S, Liu M, Hirota JA, Li J, Ju W, Fan Y, Kelly MM, Ye B, Orser B, O'Byrne PM, Inman MD, Yang X, Lu WY. A GABAergic system in airway epithelium is essential for mucus overproduction in asthma. Nat. Med. 13: 862-867 (2007). *

• Xie H, He SH. Roles of histamine and its receptors in allergic and inflammatory bowel diseases. World J. Gastroenterol. 11: 2851-2857 (2005). *

• Xu G, Mou Z, Jiang H, Cheng L, Shi J, Xu R, Oh Y, Li H. A possible role of CD4+CD25+ T cells as well as transcription factor Foxp3 in the dysregulation of allergic rhinitis. Laryngoscope 117: 876-880 (2007).

• Xu G, Zhang L, Wang DY, Xu R, Liu Z, Han DM, Wang XD, Zuo KJ, Li HB. Opposing roles of IL-17A and IL-25 in the regulation of TSLP production in human nasal epithelial cells. Allergy Nov 25 [Epub ahead of print] (2009). *

• Xu J, Postma DS, Howard TD, Koppelman GH, Zheng SL, Stine OC, Bleecker ER, Meyers DA. Major genes regulating total serum immunoglobulin E levels in families with asthma. Am. J. Hum. Genet. 67: 1163-1173 (2000). *

• Xu W, Celeridad M, Sankar S, Webb DR, Bennett BL. CC-4047 promotes Th1 cell differentiation and reprograms polarized human Th2 cells by enhancing transcription factor T-bet. Clin. Immunol. 128: 392-399 (2008).

• Xu X, Rivkind A, Pikarsky A, Pappo O, Bischoff SC, Levi-Schaffer F. Mast cells and eosinophils have a potential profibrogenic role in Crohn disease. Scand. J. Gastroenterol. 39: 440-447 (2004). *

• Xystrakis E, Boswell SE, Hawrylowicz CM. T regulatory cells and the control of allergic disease. Expert Opin. Biol. Ther. 6: 121-133 (2006).

• Xystrakis E, Kusumakar S, Boswell S, Peek E, Urry Z, Richards DF, Adikibi T, Pridgeon C, Dallman M, Loke TK, Robinson DS, Barrat FJ, O'Garra A, Lavender P, Lee TH, Corrigan C, Hawrylowicz CM. Reversing the defective induction of IL-10-secreting regulatory T cells in glucocorticoid-resistant asthma patients. J. Clin. Invest. 116: 146-155 (2006). *

• Yamada R, Ymamoto K. Recent findings on genes associated with inflammatory disease. Mutat. Res. 573: 136-151 (2005).

• Yamaguchi A, Koda T, Abe H, Sato M, Li J, Sakai T, Togashi Y, Shinohara Y, Ikeda H, Nishimura T. Development of a functional cDNA array for evaluation of the Th1/Th2 balance. Immunol. Lett. 101: 95-103 (2005).

• Yamamoto K, Kawamura I, Ito J, Mitsuyama M. Modification of allergic inflammation in murine model of rhinitis by different bacterial ligands: involvement of mast cells and dendritic cells. Clin. Exp. Allergy 36: 760-769 (2006). *

• Yamamoto M, Yamauchi T, Okano K, Takahashi M, Watabe S, Yamamoto Y. Tranilast, an anti-allergic drug, down-regulates the growth of cultured neurofibroma cells derived from neurofibromatosis type 1. Tohoku J. Exp. Med. 217: 193-201 (2009). *

• Yamanaka K, Saito J, Nakata W, Sato M, Abe T, Mori N, Sekii K, Yoshioka T, Itatani H. A case of drug-induced colitis like ulcerative colitis during IL-2 therapy for multiple bone metastasis after operation of kidney cancer. Nippon Hinyokika Gakkai Zasshi 100: 586-589 (2009).

• Yamasaki S, Saito T. Progress in allergy signal research on mast cells: signal regulation of multiple mast cell responses through FcepsilonRI. J. Pharmacol. Sci. 106: 336-340 (2008). *

• Yamashita M, Nakayama T. Progress in allergy signal research on mast cells: regulation of allergic airway inflammation through Toll-like receptor 4-mediated modification of mast cell function. J. Pharmacol. Sci. 106: 332-335 (2008). *

• Yamazaki K, Murray JA, Kita H. Innate immunomodulatory effects of cereal grains through induction of IL-10. J. Allergy Clin. Immunol. 121: 172-178 (2008). *

• Yang IA, Holgate ST, Holloway JW. Toll-like receptor polymorphisms and allergic disease: interpreting the evidence from genetic studies. Clin. Exp. Allergy 34: 163-166 (2004).

• Yang J, Qiao HL, Zhang YW, Jia LJ, Tian X, Gao N. HLA-DRB genotype and specific IgE responses in patients with allergies to penicillins. Chin. Med. J. (Engl.) 119: 458-466 (2006).

• Yang KD, Liu CA, Chang JC, Chuang H, Ou CY, Hsu TY, Wang CL. Polymorphism of the immune-braking gene CTLA-4 (+49) involved in gender discrepancy of serum total IgE levels and allergic diseases. Clin. Exp. Allergy 34: 32-37 (2004). *

• Yao C, Sakata D, Esaki Y, Li Y, Matsuoka T, Kuroiwa K, Sugimoto Y, Narumiya S. Prostaglandin E2-EP4 signaling promotes immune inflammation through TH1 cell differentiation and TH17 cell expansion. Nat. Med. 15: 633-640 (2009). *

• Yao TC, Kuo ML, See LC, Chen LC, Yan DC, Ou LS, Shaw CK, Huang JL. The RANTES promoter polymorphism: a genetic risk factor for near-fatal asthma in Chinese children. J. Allergy Clin. Immunol. 111: 1285-1292 (2003). *

• Yazdanbakhsh M, Kremsner PG, van Ree R. Allergy, parasites, and the hygiene hypothesis. Science 296: 490-494 (2002). *

• Yazdanbakhsh M, Matricardi PM. Parasites and the hygiene hypothesis: regulating the immune system? Clin. Rev. Allergy Immunol. 26: 15-24 (2004). *

• Yazdanbakhsh M, van den Biggelaar A, Maizels RM. Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease. Trends Immunol. 22: 372-377 (2001). *

• Yel L. Selective IgA deficiency. J. Clin. Immunol. 30: 10-16 (2010). *

• Yel L, Ramanuja S, Gupta S. Clinical and immunological features in IgM deficiency. Int. Arch. Allergy Immunol. 150: 291-298 (2009).

• Yin H, Liu W, Goleniewsk K, Porter NA, Morrow JD, Peebles RS Jr. Dietary supplementation of omega-3 fatty acid-containing fish oil suppresses F2-isoprostanes but enhances inflammatory cytokine response in a mouse model of ovalbumin-induced allergic lung inflammation. Free Radic. Biol. Med. 47: 622-628 (2009).

• Yin WD, Yang YQ, Zhang JS. Are parasitic infections advantageous to humans? Zhongguo Ji Sheng Chong Xue Yu Ji Sheng Chong Bing Za Zhi 27: 274-279 (2009).

• Yokoi T, Amakawa R, Tanijiri T, Sugimoto H, Torii Y, Amuro H, Son Y, Tajima K, Liu YJ, Ito T, Fukuhara S. Mycobacterium bovis Bacillus Calmette-Guerin suppresses inflammatory Th2 responses by inducing functional alteration of TSLP-activated dendritic cells. Int. Immunol. 20: 1321-1329 (2008).

• Yoshida H. Immune regulation by IL-27 for therapeutic usage. Nihon Rinsho Meneki Gakkai Kaishi 32: 202-213 (2009).

• Yoshida H, Nakaya M, Miyazaki Y. Interleukin 27: a double-edged sword for offense and defense. J. Leukoc. Biol. 86: 1295-1303 (2009). *

• Yoshida H, Yoshiyuki M. Regulation of immune responses by interleukin-27. Immunol. Rev. 226: 234-247 (2008). *

• Yoshida H, Yoshiyuki M. Interleukin 27 signaling pathways in regulation of immune and autoimmune responses. Int. J. Biochem. Cell. Biol. 40: 2379-2383 (2008). *

• Yoshida N, Isozaki Y, Takagi T, Takenaka S, Uchikawa R, Arizono N, Yoshikawa T, Okanoue T. Review article: anti-tryptase therapy in inflammatory bowel disease. Aliment. Pharmacol. Ther. 24 Suppl. 4: 249-255 (2006).

• Yoshimoto T, Yoshimoto T, Yasuda K, Mizuguchi J, Nakanishi K. IL-27 suppresses Th2 cell development and Th2 cytokines production from polarized Th2 cells: a novel therapeutic way for Th2-mediated allergic inflammation. J. Immunol. 179: 4415-4423 (2007). *

• Yoshioka M, Fukuishi N, Iriguchi S, Ohsaki K, Yamanobe H, Inukai A, Kurihara D, Imajo N, Yasui Y, Matsui N, Tsujita T, Ishii A, Seya T, Takahama M, Akagi M. Lipoteichoic acid downregulates FcepsilonRI expression on human mast cells through Toll-like receptor 2. J. Allergy Clin. Immunol. 120: 452-461 (2007). *

• Youdim A, Vasiliauskas EA, Targan SR, Papadakis KA, Ippoliti A, Dubinsky MC, Lechago J, Paavola J, Loane J, Lee SK, Gaiennie J, Smith K, Do J, Abreu MT. A pilot study of adalimumab in infliximab-allergic patients. Inflamm. Bowel Dis. 10: 333-338 (2004). *

• Young HW, Williams OW, Chandra D, Bellinghausen LK, Perez G, Suarez A, Tuvim MJ, Roy MG, Alexander SN, Moghaddam SJ, Adachi R, Blackburn MR, Dickey BF, Evans CM. Central role of MUC5AC expression in mucous metaplasia and its regulation by conserved 5' elements. Am. J. Respir. Cell. Mol. Biol. 37: 273-290 (2007). *

• Yu B, Shao Y, Zhang J, Dong XL, Liu WL, Yang H, Liu L, Li MH, Yue CF, Fang ZY, Zhang C, Hu XP, Chen BC, Wu Q, Chen YW, Zhang W, Wan J. Polymorphisms in human histamine receptor H4 gene are associated with atopic dermatitis. Br. J. Dermatol. Mar 1 [Epub ahead of print] (2010).

• Yu P, Gregg RK, Bell JJ, Ellis JS, Divekar R, Lee HH, Jain R, Waldner H, Hardaway JC, Collins M, Kuchroo VK, Zaghouani H. Specific T regulatory cells display broad suppressive functions against experimental allergic encephalomyelitis upon activation with cognate antigen. J. Immunol. 174: 6772-6780 (2005). *

• Yu S, Zhang R, Liu G, Wen W, Shen X. Experiment of genes expression of chemokines and their receptors in allergic rhinitis with gene chip. Lin Chuang Er Bi Yan Hou Ke Za Zhi 19: 52-54 (2005).

• Yusuf N, Nasti TH, Huang CM, Huber BS, Jaleel T, Lin HY, Xu H, Elmets CA. Heat shock proteins HSP27 and HSP70 are present in the skin and are important mediators of allergic contact hypersensitivity. J. Immunol. 182: 675-683 (2009). *

• Yusuf N, Nasti TH, Katiyar SK, Jacobs MK, Seibert MD, Ginsburg AC, Timares L, Xu H, Elmets CA. Antagonistic roles of CD4+ and CD8+ T-cells in 7,12-dimethylbenz(a)anthracene cutaneous carcinogenesis. Cancer Res. 68: 3924-3930 (2008). *

• Zaborsky N, Brunner M, Wallner M, Himly M, Karl T, Schwarzenbacher R, Ferreira F, Achatz G. Antigen aggregation decides the fate of the allergic immune response. J. Immunol. 184: 725-735 (2010).

• Zaccone P, Fehervari Z, Phillips JM, Dunne DW, Cooke A. Parasitic worms and inflammatory diseases. Parasite Immunol. 28: 515-523 (2006). *

• Zaghouani H, Hoeman CM, Adkins B. Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells. Trends Immunol. 30: 585-591 (2009). *

• Zakrzewska A, Kobos J, Gryczynska D. Expression of the chosen proapoptotic and activation markers in adenoids in children with allergic rhinitis. Otolaryngol. Pol. 58: 747-752 (2004).

• Zandman-Goddard G, Shoenfeld Y. Mycophenolate mofetil in animal models of autoimmune disease. Lupus 14 Suppl. 1: s12-s16 (2005).

• Zeifang F, Oberle D, Nierhoff C, Richter W, Moradi B, Schmitt H. Autologous chondrocyte implantation using the original periosteum-cover technique versus matrix-associated autologous chondrocyte implantation: a randomized clinical trial. Am. J. Sports Med. Dec 4 [Epub ahead of print] (2009).

• Zeyrek D, Tanac R, Altinoz S, Berdeli A, Gulen F, Koksoy H, Demir E. FcgammaRIIIa-V/F 158 polymorphism in Turkish children with asthma bronchiale and allergic rhinitis. Pediatr. Allergy Immunol. 19: 20-24 (2008). *

• Zhang G, Goldblatt J, Lesouef PN. Does the relationship between IgE and the CD14 gene depend on ethnicity? Allergy 63: 1411-1417 (2008). *

• Zhang J, Lee SM, Shannon S, Gao B, Chen W, Chen A, Divekar R, McBurney MW, Braley-Mullen H, Zaghouani H, Fang D. The type III histone deacetylase Sirt1 is essential for maintenance of T cell tolerance in mice. J. Clin. Invest. 119: 3048-3058 (2009). *

• Zhang L, Oh SY, Wu X, Oh MH, Wu F, Schroeder JT, Takemoto CM, Zheng T, Zhu Z. SHP-1 deficient mast cells are hyperresponsive to stimulation and critical in initiating allergic inflammation in the lung. J. Immunol. Dec 30 [Epub ahead of print] (2009).

• Zhang L, Wang X, Han D, Duan H, Zhao Y. Association of single nucleotide polymorphisms in GATA-3 with allergic rhinitis. Acta Otolaryngol. 129: 190-194 (2009).

• Zhang L, Zhang Y, Desrosiers M, Wang C, Zhao Y, Han D. Genetic association study of FOXP3 polymorphisms in allergic rhinitis in Chinese population. Hum. Immunol. 70: 930-934 (2009).

• Zhang S, Zhong J, Yang P, Gong F, Wang CY. HMGB1, an innate alarmin, in the pathogenesis of type 1 diabetes. Int. J. Clin. Exp. Pathol. 3: 24-38 (2009).

• Zhang X, Lewkowich IP, Kohl G, Clark JR, Wills-Karp M, Kohl J. A protective role for C5a in the development of allergic asthma associated with altered levels of B7-H1 and B7-DC on plasmacytoid dendritic cells. J. Immunol. 182: 5123-5130 (2009).

• Zhang X, Su D, Zhang X, Sui H, Jin L, Lu F, Zhang J. Association of ADAM33 gene polymorphisms with adult concomitant allergic rhinitis and asthma in Chinese Han population. Mol. Biol. Rep. 36: 1505-1509 (2009). *

• Zhang Y, Wells J, Buist R, Peeling J, Yong VW, Mitchell JR. A novel MRI texture analysis of demyelination and inflammation in relapsing-remitting experimental allergic encephalomyelitis. Med. Image Comput. Comput. Assist. Interv. Int. Conf. Med. Image Comput. Comput. Assist Interv. 9: 760-767 (2006).

• Zhao Y, Balato A, Fishelevich R, Chapoval A, Mann DL, Gaspari AA. Th17/Tc17 infiltration and associated cytokine gene expression in elicitation phase of allergic contact dermatitis. Br. J. Dermatol. 161: 1301-1306 (2009). *

• Zhao Y, Yang H, Zheng YB, Wong YO, Leung PC. The effects of Fructus xanthii extract on cytokine release from human mast cell line (HMC-1) and peripheral blood mononuclear cells. Immunopharmacol. Immunotoxicol. 30: 543-552 (2008).

• Zhao Y, Yang J, Gao YD, Guo W. Th17 immunity in patients with allergic asthma. Int. Arch. Allergy Immunol. 151: 297-307 (2009).

• Zhou HY, Shin EM, Guo LY, Zou LB, Xu GH, Lee SH, Ze KR, Kim EK, Kang SS, Kim YS. Anti-inflammatory activity of 21(alpha, beta)-methylmelianodiols, novel compounds from Poncirus trifoliata Rafinesque. Eur. J. Pharmacol. 572: 239-248 (2007).

• Zhou SR, Moscarello MA, Whitaker JN. The effects of citrullination or variable amino-terminus acylation on the encephalitogenicity of human myelin basic protein in the PL/J mouse. J. Neuroimmunol. 62: 147-152 (1995).

• Zhou Y, Zhou X, Wang X. 1,25-Dihydroxyvitamin D(3) prevented allergic asthma in a rat model by suppressing the expression of inducible nitric oxide synthase. Allergy Asthma Proc. 29: 258-267 (2008).

• Zhou Z, Song X, Li B, Greene MI. FOXP3 and its partners: structural and biochemical insights into the regulation of FOXP3 activity. Immunol. Res. 42: 19-28 (2008). *

• Zhu FG, Kandimalla ER, Yu D, Agrawal S. Oral administration of a synthetic agonist of Toll-like receptor 9 potently modulates peanut-induced allergy in mice. J. Allergy Clin. Immunol. 120: 631-637 (2007).

• Zhu J, Davidson TS, Wei G, Jankovic D, Cui K, Schones DE, Guo L, Zhao K, Shevach EM, Paul WE. Down-regulation of Gfi-1 expression by TGF-beta is important for differentiation of Th17 and CD103+ inducible regulatory T cells. J. Exp. Med. 206: 329-341 (2009). *

• Zhu J, Yamane H, Paul WE. Differentiation of effector CD4 T cell populations. Annu. Rev. Immunol. Jan 4 [Epub ahead of print] (2010). *

• Zhu YN, Zhong XG, Feng JQ, Yang YF, Fu YF, Ni J, Liu QF, Tang W, Zhao WM, Zuo JP. Periplocoside E inhibits experimental allergic encephalomyelitis by suppressing IL-12-dependent CCR5 expression and IFN-gamma-dependent CXCR3 expression in T lymphocytes. J. Pharmacol. Exp. Ther. 318: 1153-1162 (2006). *

• Ziegler SF, Liu YJ. Thymic stromal lymphopoietin in normal and pathogenic T cell development and function. Nat. Immunol. 7: 709-714 (2006). *

• Zirbes JM, Milla CE. Steroid-sparing effect of omalizumab for allergic bronchopulmonary aspergillosis and cystic fibrosis. Pediatr. Pulmonol. 43: 607-610 (2008).

• Zmudzinska M, Czarnecka-Operacz M, Silny W. Principles of dermatologic ultrasound diagnostics. Acta Dermatovenerol. Croat. 16: 126-129 (2008).

• Zochling J, Bohl-Buhler MH, Baraliakos X, Feldtkeller E, Braun J. The high prevalence of infections and allergic symptoms in patients with ankylosing spondylitis is associated with clinical symptoms. Clin. Rheumatol. 25: 648-658 (2006). *

• Zozulya AA, Gabaeva MV, Sokolov OY, Surkina ID, Kost NV. Personality, coping style, and constitutional neuroimmunology. J. Immunotoxicol. 5: 221-225 (2008).

• Zschieschang P, Hiepe F, Gromnica-Ihle E, Roots I, Cascorbi I. Lack of association between arylamine N-acetyltransferase 2 (NAT2) polymorphism and systemic lupus erythematosus. Pharmacogenetics 12: 559-563 (2002).

• Zuberi RI, Ge XN, Jiang S, Bahaie NS, Kang BN, Hosseinkhani RM, Frenzel EM, Fuster MM, Esko JD, Rao SP, Sriramarao P. Deficiency of endothelial heparan sulfates attenuates allergic airway inflammation. J. Immunol. 183: 3971-3979 (2009).

Number of references = 1995

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