major histocompatibility complex (MHC), Primary Sclerosing Cholangitis Literature

Primary Sclerosing Cholangitis Literature

Home Page

FAQ

PSC Partners

www Resources

Scientific Literature

Scientific Literature, major histocompatibility complex (MHC)

Abdeen H, Heggarty S, Hawkins SA, Hutchinson M, McDonnell GV, Graham CA. Mapping candidate non-MHC susceptibility regions to multiple sclerosis. Genes Immun. 7: 494-502 (2006). *
Abe M, Thomson AW. Chapter 4. Antigen processing and presentation in the liver. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 49-59 (2007). *
Abe R. Regulation of immune response by T cell co-signaling. Nihon Rinsho Meneki Gakkai Kaishi 28: 21-32 (2005).
Abe Y, Urakami H, Ostanin D, Zibari G, Hayashida T, Kitagawa Y, Grisham MB. Induction of Foxp3-expressing regulatory T-cells by donor blood transfusion is required for tolerance to rat liver allografts. PLoS One 4: e7840 (2009). *
Abecassis S, Giustiniani J, Meyer N, Schiavon V, Ortonne N, Campillo JA, Bagot M, Bensussan A. Identification of a novel CD160(+)CD4(+) T-lymphocyte subset in the skin: a possible role for CD160 in skin inflammation. J. Invest. Dermatol. 127: 1161-1166 (2007). *
Abele R, Tampe R. Modulation of the antigen transport machinery TAP by friends and enemies. FEBS Lett. 580: 1156-1163 (2006). *
Abi-Rached L, Kuhl H, Roos C, Ten Hallers B, Zhu B, Carbone L, de Jong PJ, Mootnick AR, Knaust F, Reinhardt R, Parham P, Walter L. A small, variable, and irregular killer cell Ig-like receptor locus accompanies the absence of MHC-C and MHC-G in gibbons. J. Immunol. Dec 21 [Epub ahead of print] (2009).
Abraham LJ, Du DC, Zahedi K, Dawkins RL, Whitehead AS. Haplotypic polymorphisms of the TNFB gene. Immunogenetics 33: 50-53 (1991).
Abraham LJ, French MA, Dawkins RL. Polymorphic MHC ancestral haplotypes affect the activity of tumour necrosis factor-alpha. Clin. Exp. Immunol. 92: 14-18 (1993). *
Abraham LJ, Kroeger KM. Impact of the -308 TNF promoter polymorphism on the transcriptional regulation of the TNF gene: relevance to disease. J. Leukoc. Biol. 66: 562-566 (1999). *
Abraham LJ, Leelayuwat C, Grimsley G, Degli-Esposti MA, Mann A, Zhang WJ, Christiansen FT, Dawkins RL. Sequence differences between HLA-B and TNF distinguish different MHC ancestral haplotypes. Tissue Antigens 39: 117-121 (1992).
Abraham RS, Wen L, Marietta EV, David CS. Type 1 diabetes-predisposing MHC alleles influence the selection of glutamic acid decarboxylase (GAD) 65-specific T cells in a transgenic model. J. Immunol. 166: 1370-1379 (2001). *
Abreu MT. The pathogenesis of inflammatory bowel disease: translational implications for clinicians. Curr. Gastroenterol. Rep. 4: 481-489 (2002).
Abreu MT, Yang H. Is genetic testing in IBD ready for prime time? Am. J. Gastroenterol. 99: 316-318 (2004). *
Acha-Orbea H, MacDonald HR. Superantigens of mouse mammary tumor virus. Annu. Rev. Immunol. 13: 459-486 (1995). *
Ackerman HC, Ribas G, Jallow M, Mott R, Neville M, Sisay-Joof F, Pinder M, Campbell RD, Kwiatkowski DP. Complex haplotypic structure of the central MHC region flanking TNF in a West African population. Genes Immun. 4: 476-486 (2003). *
Adair SJ, Carr TM, Fink MJ, Slingluff CL Jr, Hogan KT. The TAG family of cancer/testis antigens is widely expressed in a variety of malignancies and gives rise to HLA-A2-restricted epitopes. J. Immunother. 31: 7-17 (2008).
Adams EJ, Chien YH, Garcia KC. Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22. Science 308: 227-231 (2005). *
Adams EJ, Juo ZS, Venook RT, Boulanger MJ, Arase H, Lanier LL, Garcia KC. Structural elucidation of the m157 mouse cytomegalovirus ligand for Ly49 natural killer cell receptors. Proc. Natl. Acad. Sci. U.S.A. 104: 10128-10133 (2007). *
Adams S, Lowes MA, O'Neill DW, Schachterle S, Romero P, Bhardwaj N. Lack of functionally active melan-A(26-35)-specific T cells in the blood of HLA-A2(+) vitiligo patients. J. Invest. Dermatol. 128: 1977-1980 (2008). *
Adamus G, Karren LJ, Mooney J, Burrows GG. A promising therapeutic approach for treatment of posterior uveitis: recombinant T cell receptor ligand protects Lewis rats from acute and recurrent experimental autoimmune uveitis. Ophthalmic Res. 44: 24-33 (2010).
Adar T, Ilan Y. beta-Glycosphingolipids as immune modulators. J. Immunotoxicol. 5: 209-220 (2008).
Adarichev VA, Bardos T, Christodoulou S, T Phillips M, Mikecz K, Glant TT. Major histocompatibility complex controls susceptibility and dominant inheritance, but not the severity of the disease in mouse models of rheumatoid arthritis. Immunogenetics 54: 184-192 (2002). *
Adarichev VA, Glant TT. Experimental spondyloarthropathies: animal models of ankylosing spondylitis. Curr. Rheumatol. Rep. 8: 267-274 (2006).
Affolter VK, Moore PF. Feline progressive histiocytosis. Vet. Pathol. 43: 646-655 (2006). *
Afzali B, Lechler RI, Hernandez-Fuentes MP. Allorecognition and the alloresponse: clinical implications. Tissue Antigens 69: 545-556 (2007). *
Agarwal K, Czaja AJ, Donaldson PT. A functional Fas promoter polymorphism is associated with a severe phenotype in type 1 autoimmune hepatitis characterized by early development of cirrhosis. Tissue Antigens 69: 227-235 (2007). *
Agarwal K, Jones DE, Bassendine MF. Genetic susceptibility to primary biliary cirrhosis. Eur. J. Gastroenterol. Hepatol. 11: 603-606 (1999).
Agarwal K, Jones DE, Daly AK, James OF, Vaidya B, Pearce S, Bassendine MF. CTLA-4 gene polymorphism confers susceptibility to primary biliary cirrhosis. J. Hepatol. 32: 538-541 (2000). *
Aguillon JC, Cruzat A, Aravena O, Salazar L, Llanos C, Cuchacovich M. Could single-nucleotide polymorphisms (SNPs) affecting the tumour necrosis factor promoter be considered as part of rheumatoid arthritis evolution? Immunobiology 211: 75-84 (2006).
Ahlen MT, Husebekk A, Killie MK, Skogen B, Stuge TB. T cell responses associated with neonatal alloimmune thrombocytopenia: isolation of HPA-1a-specific, HLA-DRB3*0101-restricted CD4+ T cells. Blood 113: 3838-3844 (2009). *
Ahlenstiel G, Rehermann B. Chapter 6. Hepatic NK, NKT, and T cells. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 71-82 (2007). *
Ahmad T, Marshall SE, Mulcahy-Hawes K, Orchard T, Crawshaw J, Armuzzi A, Neville M, van Heel D, Barnardo M, Welsh KI, Jewell DP, Bunce M. High resolution MIC genotyping: design and application to the investigation of inflammatory bowel disease susceptibility. Tissue Antigens 60: 164-179 (2002). *
Ahmad T, Neville M, Marshall SE, Armuzzi A, Mulcahy-Hawes K, Crawshaw J, Sato H, Ling KL, Barnardo M, Goldthorpe S, Walton R, Bunce M, Jewell DP, Welsh KI. Haplotype-specific linkage disequilibrium patterns define the genetic topography of the human MHC. Hum. Mol. Genet. 12: 647-656 (2003). *
Ahmad T, Satsangi J, McGovern D, Bunce M, Jewell DP. Review article: the genetics of inflammatory bowel disease. Aliment. Pharmacol. Ther. 15: 731-748 (2001). *
Ahmed AR, Yunis EJ, Khatri K, Wagner R, Notani G, Awdeh Z, Alper CA. Major histocompatibility complex haplotype studies in Ashkenazi Jewish patients with pemphigus vulgaris. Proc. Natl. Acad. Sci. U.S.A. 87: 7658-7662 (1990). *
Ahn KO, Lim SW, Li C, Yang HJ, Ghee JY, Kim JY, Kim SH, Kim J, Yang CW. Influence of angiotensin II on expression of Toll-like receptor 2 and maturation of dendritic cells in chronic cyclosporine nephropathy. Transplantation 83: 938-947 (2007).
Ahn S, Lee G, Yang SJ, Lee D, Lee S, Shin HS, Kim MC, Lee KN, Palmer DC, Theoret MR, Jenkinson EJ, Anderson G, Restifo NP, Kim MG. TSCOT (+) thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS Biol. 6: e191 (2008). *
Ahn SC, Kim GY, Kim JH, Baik SW, Han MK, Lee HJ, Moon DO, Lee CM, Kang JH, Kim BH, Oh YH, Park YM. Epigallocatechin-3-gallate, constituent of green tea, suppresses the LPS-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and NF-kappaB. Biochem. Biophys. Res. Commun. 313: 148-155 (2004). *
Ahuja SS, Zhao S, Bellido T, Plotkin LI, Jimenez F, Bonewald LF. CD40 ligand blocks apoptosis induced by tumor necrosis factor alpha, glucocorticoids, and etoposide in osteoblasts and the osteocyte-like cell line murine long bone osteocyte-Y4. Endocrinology 144: 1761-1769 (2003). *
Aisenberg J, Legnani PE, Nilubol N, Cobrin GM, Ellozy SH, Hegazi RAF, Yager J, Bodian C, Gorfine SR, Bauer JJ, Plevy SE, Sachar DB. Are pANCA, ASCA, or cytokine gene polymorphisms associated with pouchitis? Long-term follow-up in 102 ulcerative colitis patients. Am. J. Gastroenterol. 99: 432-441 (2004). *
Aissani B, Ogwaro KM, Shrestha S, Tang J, Breen EC, Wong HL, Jacobson LP, Rabkin CS, Ambinder RF, Martinez-Maza O, Kaslow RA. The major histocompatibility complex conserved extended haplotype 8.1 in AIDS-related non-Hodgkin lymphoma. J. Acquir. Immune Defic. Syndr. Aug 3 [Epub ahead of print] (2009).
Ajjan RA, Weetman AP. New understanding of the role of cytokines in the pathogenesis of Graves' ophthalmopathy. J. Endocrinol. Invest. 27: 237-245 (2004).
Akaishi PM, Cruz AA, Silva FL, De Lourdes Veronesi Rodrigues M, Maciel LM, Donadi EA. The role of major histocompatibility complex alleles in the susceptibility of Brazilian patients to develop the myogenic type of Graves' orbitopathy. Thyroid 18: 443-447 (2008).
Akashi S, Sho M, Kashizuka H, Hamada K, Ikeda N, Kuzumoto Y, Tsurui Y, Nomi T, Mizuno T, Kanehiro H, Hisanaga M, Ko S, Nakajima Y. A novel small-molecule compound targeting CCR5 and CXCR3 prevents acute and chronic allograft rejection. Transplantation 80: 378-384 (2005).
Akatsuka Y, Morishima Y, Kuzushima K, Kodera Y, Takahashi T. Minor histocompatibility antigens as targets for immunotherapy using allogeneic immune reactions. Cancer Sci. 98: 1139-1146 (2007). *
Akazawa T, Ebihara T, Okuno M, Okuda Y, Shingai M, Tsujimura K, Takahashi T, Ikawa M, Okabe M, Inoue N, Okamoto-Tanaka M, Ishizaki H, Miyoshi J, Matsumoto M, Seya T. Antitumor NK activation induced by the Toll-like receptor 3-TICAM-1 (TRIF) pathway in myeloid dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 104: 252-257 (2007). *
Akbari O, Faul JL, Hoyte EG, Berry GJ, Wahlstrom J, Kronenberg M, DeKruyff RH, Umetsu DT. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N. Engl. J. Med. 354: 1117-1129 (2006). *
Akesson E, Oturai A, Berg J, Fredrikson S, Andersen O, Harbo HF, Laaksonen M, Myhr KM, Nyland HI, Ryder LP, Sandberg-Wollheim M, Sorensen PS, Spurkland A, Svejgaard A, Holmans P, Compston A, Hillert J, Sawcer S. A genome-wide screen for linkage in Nordic sib-pairs with multiple sclerosis. Genes Immun. 3: 279-285 (2002). *
Akilesh S, Petkova S, Sproule TJ, Shaffer DJ, Christianson GJ, Roopenian D. The MHC class I-like Fc receptor promotes humorally mediated autoimmune disease. J. Clin. Invest. 113: 1328-1333 (2004). *
Akkad DA, Jagiello P, Szyld P, Goedde R, Wieczorek S, Gross WL, Epplen JT. Promoter polymorphism rs3087456 in the MHC class II transactivator gene is not associated with susceptibility for selected autoimmune diseases in German patient groups. Int. J. Immunogenet. 33: 59-61 (2006). *
Al-Kandari W, Jambunathan S, Navalgund V, Koneni R, Freer M, Parimi N, Mudhasani R, Fontes JD. ZXDC, a novel zinc finger protein that binds CIITA and activates MHC gene transcription. Mol. Immunol. 44: 311-321 (2007). *
Al-Kandari W, Koneni R, Navalgund V, Aleksandrova A, Jambunathan S, Fontes JD. The zinc finger proteins ZXDA and ZXDC form a complex that binds CIITA and regulates MHC II gene transcription. J. Mol. Biol. 369: 1175-1187 (2007). *
Al-Swailem R, Al-Rayes H, Sobki S, Arfin M, Tariq M. HLA-DRB1 association in Saudi rheumatoid arthritis patients. Rheumatol. Int. 26: 1019-1024 (2006). *
Al-Tonbary Y, Abdel-Razek N, Zaghloul H, Metwaly S, El-Deek B, El-Shawaf R. HLA class II polymorphism in Egyptian children with lymphomas. Hematology 9: 139-145 (2004).
Alba A, Planas R, Clemente X, Carrillo J, Ampudia R, Puertas MC, Pastor X, Tolosa E, Pujol-Borrell R, Verdaguer J, Vives-Pi M. Natural killer cells are required for accelerated type 1 diabetes driven by interferon-beta. Clin. Exp. Immunol. 151: 467-475 (2008). *
Albaghdadi H, Robinson N, Finlay B, Krishnan L, Sad S. Selectively reduced intracellular proliferation of Salmonella enterica serovar typhimurium within APCs limits antigen presentation and development of a rapid CD8 T cell response. J. Immunol. 183: 3778-3787 (2009).
Albanesi C, Cavani A, Girolomoni G. IL-17 is produced by nickel-specific T lymphocytes and regulates ICAM-1 expression and chemokine production in human keratinocytes: synergistic or antagonist effects with IFN-gamma and TNF-alpha. J. Immunol. 162: 494-502 (1999). *
Albani S, Roudier J. Molecular basis for the association between HLA DR4 and rheumatoid arthritis. From the shared epitope hypothesis to a peptidic model of rheumatoid arthritis. Clin. Biochem. 25: 209-212 (1992).
Albanidou-Farmaki E, Deligiannidis A, Markopoulos AK, Katsares V, Farmakis K, Parapanissiou E. HLA haplotypes in recurrent aphthous stomatitis: a mode- of inheritance? Int. J. Immunogenet. 35: 427-432 (2008). *
Albertella MR, Campbell RD. Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins. Hum. Mol. Genet. 3: 793-799 (1994).
Albertella MR, Jones H, Thomson W, Olavesen MG, Campbell RD. Localization of eight additional genes in the human major histocompatibility complex, including the gene encoding the casein kinase II beta subunit (CSNK2B). Genomics 36: 240-251 (1996). *
Aldersley MA, Hamlin PJ, Jones PF, Markham AF, Robinson PA, Howdle PD. No polymorphism in the tissue transglutaminase gene detected in coeliac disease patients. Scand. J. Gastroenterol. 35: 61-63 (2000). *
Alfirevic A, Mills T, Harrington P, Pinel T, Sherwood J, Jawaid A, Smith JC, March RE, Barratt BJ, Chadwick DW, Kevin Park B, Pirmohamed M. Serious carbamazepine-induced hypersensitivity reactions associated with the HSP70 gene cluster. Pharmacogenet. Genomics 16: 287-296 (2006).
Alfonso C, Karlsson L. Nonclassical MHC class II molecules. Annu. Rev. Immunol. 18: 113-142 (2000). *
Ali A, Martin JM 4th. Hair growth in patients alopecia areata totalis after treatment with simvastatin and ezetimibe. J. Drugs Dermatol. 9: 62-64 (2010).
Alizadeh BZ, Eerligh P, van der Slik AR, Shastry A, Zhernakova A, Valdigem G, Bruining JG, Sanjeevi CB, Wijmenga C, Roep BO, Koeleman BP. MICA marks additional risk factors for type 1 diabetes on extended HLA haplotypes: an association and meta-analysis. Mol. Immunol. 44: 2806-2812 (2007). *
Alizadeh M, Babron MC, Birebent B, Matsuda F, Quelvennec E, Liblau R, Cournu-Rebeix I, Momigliano-Richiardi P, Sequeiros J, Yaouanq J, Genin E, Vasilescu A, Bougerie H, Trojano M, Martins Silva B, Maciel P, Clerget-Darpoux F, Clanet M, Edan G, et al. Genetic interaction of CTLA-4 with HLA-DR15 in multiple sclerosis patients. Ann. Neurol. 54: 119-122 (2003). *
Alkemade A, Friesema EC, Kuiper GG, Wiersinga WM, Swaab DF, Visser TJ, Fliers E. Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. Eur. J. Endocrinol. 154: 491-500 (2006). *
Alkhateeb A, Stetler GL, Old W, Talbert J, Uhlhorn C, Taylor M, Fox A, Miller C, Dills DG, Ridgway EC, Bennett DC, Fain PR, Spritz RA. Mapping of an autoimmunity susceptibility locus (AIS1) to chromosome 1p31.3-p32.2. Hum. Mol. Genet. 11: 661-667 (2002). *
Allcock R, Dolecki KJ, Boodhoo A, Abdul Khalil A, Wong AM, Price P. Genomic sequence and expression profile of murine Bat1a and Nfkbil1. DNA Seq. 17: 292-299 (2006).
Allcock RJ, Baluchova K, Cheong KY, Price P. Haplotypic single nucleotide polymorphisms in the central MHC gene IKBL, a potential regulator of NF-kappaB function. Immunogenetics 52: 289-293 (2001).
Allcock RJ, Christiansen FT, Price P. The central MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3,B7,DR15. Immunogenetics 49: 660-665 (1999). *
Allcock RJ, de la Concha EG, Fernandez-Arquero M, Vigil P, Conejero L, Arroyo R, Price P. Susceptibility to multiple sclerosis mediated by HLA-DRB1 is influenced by a second gene telomeric of the TNF cluster. Hum. Immunol. 60: 1266-1273 (1999).
Allcock RJ, Price P, Gaudieri S, Leelayuwat C, Witt CS, Dawkins RL. Characterisation of the human central MHC gene, BAT1: genomic structure and expression. Exp. Clin. Immunogenet. 16: 98-106 (1999).
Allcock RJ, Williams JH, Price P. The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production. Genes Cells 6: 487-494 (2001). *
Allcock RJ, Windsor L, Gut IG, Kucharzak R, Sobre L, Lechner D, Garnier JG, Baltic S, Christiansen FT, Price P. High-density SNP genotyping defines 17 distinct haplotypes of the TNF block in the Caucasian population: implications for haplotype tagging. Hum. Mutat. 24: 517-525 (2004).
Allen M, Ameen H, Veal C, Evans J, Ramrakha-Jones VS, Marsland AM, Burden AD, Griffiths CE, Trembath R, Barker JW. The major psoriasis susceptibility locus PSORS1 is not a risk factor for late-onset psoriasis. J. Invest. Dermatol. 124: 103-106 (2005). *
Allen ML, Hoschtitzky JA, Peters MJ, Elliott M, Goldman A, James I, Klein NJ. Interleukin-10 and its role in clinical immunoparalysis following pediatric cardiac surgery. Crit. Care Med. 34: 2658-2665 (2006).
Allen RL, Bowness P, McMichael A. The role of HLA-B27 in spondyloarthritis. Immunogenetics 50: 220-227 (1999).
Allen RL, Trowsdale J. Recognition of classical and heavy chain forms of HLA-B27 by leukocyte receptors. Curr. Mol. Med. 4: 59-65 (2004).
Allez M, Tieng V, Nakazawa A, Treton X, Pacault V, Dulphy N, Caillat-Zucman S, Paul P, Gornet JM, Douay C, Ravet S, Tamouza R, Charron D, Lemann M, Mayer L, Toubert A. CD4(+)NKG2D(+) T cells in Crohn's disease mediate inflammatory and cytotoxic responses through MICA interactions. Gastroenterology 132: 2346-2358 (2007). *
Allison AC. Genetic control of resistance to human malaria. Curr. Opin. Immunol. 21: 499-505 (2009).
Almani M, Raffaeli S, Vider-Shalit T, Tsaban L, Fishbain V, Louzoun Y. Human self-protein CD8(+) T-cell epitopes are both positively and negatively selected. Eur. J. Immunol. 39: 1056-1065 (2009). *
Alper CA. The human immune response to hepatitis B surface antigen. Exp. Clin. Immunogenet. 12: 171-181 (1995).
Alper CA, Fleischnick E, Awdeh Z, Katz AJ, Yunis EJ. Extended major histocompatibility complex haplotypes in patients with gluten-sensitive enteropathy. J. Clin. Invest. 79: 251-256 (1987). *
Alper CA, Husain Z, Larsen CE, Dubey DP, Stein R, Day C, Baker A, Beyan H, Hawa M, Ola TO, Leslie RD. Incomplete penetrance of susceptibility genes for MHC-determined immunoglobulin deficiencies in monozygotic twins discordant for type 1 diabetes. J. Autoimmun. 27: 89-95 (2006). *
Alper CA, Larsen CE, Dubey DP, Awdeh ZL, Fici DA, Yunis EJ. The haplotype structure of the human major histocompatibility complex. Hum. Immunol. 67: 73-84 (2006). *
Alper CA, Marcus-Bagley D, Awdeh Z, Kruskall MS, Eisenbarth GS, Brink SJ, Katz AJ, Stein R, Bing DH, Yunis EJ, Schur PH. Prospective analysis suggests susceptibility genes for deficiencies of IgA and several other immunoglobulins on the [HLA-B8, SC01, DR3] conserved extended haplotype. Tissue Antigens 56: 207-216 (2000). *
Alper CA, Xu J, Cosmopoulos K, Dolinski B, Stein R, Uko G, Larsen CE, Dubey DP, Densen P, Truedsson L, Sturfelt G, Sjoholm AG. Immunoglobulin deficiencies and susceptibility to infection among homozygotes and heterozygotes for C2 deficiency. J. Clin. Immunol. 23: 297-305 (2003).
Althaus K, Greinacher A. MYH9-related platelet disorders. Semin. Thromb. Hemost. 35: 189-203 (2009).
Altiparmak F, Akalin A, Ferhatosmanoglu H. Predicting the binding affinity of MHC class II peptides. Comput. Syst. Bioinformatics Conf. 2006: 331-334 (2006). *
Aluvihare VR, Betz AG. The role of regulatory T cells in alloantigen tolerance. Immunol. Rev. 212: 330-343 (2006). *
Alvarado-Guerri R, Cabrera CM, Garrido F, Lopez-Nevot MA. TAP1 and TAP2 polymorphisms and their linkage disequilibrium with HLA-DR, -DP, and -DQ in an Eastern Andalusian population. Hum. Immunol. 66: 921-930 (2005).
Alvarez E, Moga E, Barquinero J, Sierra J, Briones J. Dendritic and tumor cell fusions transduced with adenovirus encoding CD40L eradicate B-cell lymphoma and induce a Th17-type response. Gene Ther. Dec 14 [Epub ahead of print] (2009).
Alvarez-Lafuente R, Martinez A, Garcia-Montojo M, Mas A, De Las Heras V, Dominguez-Mozo MI, Maria Del Carmen C, Lopez-Cavanillas M, Bartolome M, Gomez de la Concha E, Urcelay E, Arroyo R. MHC2TA rs4774C and HHV-6A active replication in multiple sclerosis patients. Eur. J. Neurol. Jul 29 [Epub ahead of print] (2009).
Alvarez-Ossorio L, Johannsen M, Russlies M, Kirchner H, Rink L. HLA-dependent heterogeneous T cell response to Mycoplasma arthritidis-derived superantigen (MAS). Med. Microbiol. Immunol. 185: 245-251 (1997).
Aly TA, Baschal EE, Jahromi MM, Fernando MS, Babu SR, Fingerlin TE, Kretowski A, Erlich HA, Fain PR, Rewers MJ, Eisenbarth GS. Analysis of single nucleotide polymorphisms identifies major type 1A diabetes locus telomeric of the major histocompatibility complex. Diabetes 57: 770-776 (2008). *
Aly TA, Eller E, Ide A, Gowan K, Babu SR, Erlich HA, Rewers MJ, Eisenbarth GS, Fain PR. Multi-SNP analysis of MHC region: remarkable conservation of HLA-A1-B8-DR3 haplotype. Diabetes 55: 1265-1269 (2006). *
Aly TA, Ide A, Jahromi MM, Barker JM, Fernando MS, Babu SR, Yu L, Miao D, Erlich HA, Fain PR, Barriga KJ, Norris JM, Rewers MJ, Eisenbarth GS. Extreme genetic risk for type 1A diabetes. Proc. Natl. Acad. Sci. U.S.A. 103: 14074-14079 (2006). *
Amati L, Caradonna L, Leandro G, Magrone T, Minenna M, Faleo G, Pellegrino NM, Jirillo E, Caccavo D. Immune abnormalities and endotoxemia in patients with ulcerative colitis and in their first degree relatives: attempts at neutralizing endotoxin-mediated effects. Curr. Pharm. Design 9: 1937-1945 (2003).
Ambrogini E, Toraldo G, Marcocci C. Post-menopausal osteoporosis: is it an autoimmune disease? J. Endocrinol. Invest. 28: S43-S47 (2005).
Ameen M, Allen MH, Fisher SA, Lewis CM, Cuthbert A, Kondeatis E, Vaughan RW, Murakami H, Nakagawa H, Barker JN. Corneodesmosin (CDSN) gene association with psoriasis vulgaris in Caucasian but not in Japanese populations. Clin. Exp. Dermatol. 30: 414-418 (2005). *
Amigorena S, Savina A. Intracellular mechanisms of antigen cross presentation in dendritic cells. Curr. Opin. Immunol. Feb 18 [Epub ahead of print] (2010).
Amos CI, Chen WV, Lee A, Li W, Kern M, Lundsten R, Batliwalla F, Wener M, Remmers E, Kastner DA, Criswell LA, Seldin MF, Gregersen PK. High-density SNP analysis of 642 Caucasian families with rheumatoid arthritis identifies two new linkage regions on 11p12 and 2q33. Genes Immun. 7: 277-286 (2006). *
Amroun H, Djoudi H, Busson M, Allat R, El Sherbini SM, Sloma I, Ramasawmy R, Brun M, Dulphy N, Krishnamoorthy R, Toubert A, Charron D, Abbadi MC, Tamouza R. Early-onset ankylosing spondylitis is associated with a functional MICA polymorphism. Hum. Immunol. 66: 1057-1061 (2005).
Anaya JM, Rivera D, Palacio LG, Arcos-Burgos M, Correa PA. D6S439 microsatellite identifies a new susceptibility region for primary Sjogren's syndrome. J. Rheumatol. 30: 2152-2156 (2003).
Andersen RS, Sorensen RB, Andersen MH, Straten PT. CD8 T-cell responses against cyclin B1. Clin. Cancer Res. 15: 7106-7107 (2009). *
Anderson CA, Massey DC, Barrett JC, Prescott NJ, Tremelling M, Fisher SA, Gwilliam R, Jacob J, Nimmo ER, Drummond H, Lees CW, Onnie CM, Hanson C, Blaszczyk K, Ravindrarajah R, Hunt S, Varma D, Hammond N, Lewis G, Attlesey H, Watkins N, et al. Investigation of Crohn�s disease risk loci in ulcerative colitis further defines their molecular relationship. Gastroenterology 136: 523-529.e3 (2009). *
Anderson CL, Chaudhury C, Kim J, Bronson CL, Wani MA, Mohanty S. Perspective - FcRn transports albumin: relevance to immunology and medicine. Trends Immunol. 27: 343-348 (2006). *
Anderson HA, Hiltbold EM, Roche PA. Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation. Nat. Immunol. 1: 156-162 (2000). *
Anderson KJ, Allen RL. Regulation of T-cell immunity by leucocyte immunoglobulin-like receptors: innate immune receptors for self on antigen-presenting cells. Immunology 127: 8-17 (2009). *
Anderson RP. Coeliac disease: current approach and future prospects. Intern. Med. J. 38: 790-799 (2008). *
Anderson SK, Dewar K, Goulet ML, Leveque G, Makrigiannis AP. Complete elucidation of a minimal class I MHC natural killer cell receptor haplotype. Genes Immun. 6: 481-492 (2005). *
Andersson EC, Svendsen P, Svejgaard A, Holmdahl R, Fugger L. A molecule basis for the HLA association in rheumatoid arthritis. Rev. Immunogenet. 2: 81-87 (2000).
Andersson G, Svensson AC, Setterblad N, Rask L. Retroelements in the human MHC class II region. Trends Genet. 14: 109-114 (1998). *
Andersson HA, Passeri MF, Barry MA. Rad23 as a reciprocal agent for stimulating or repressing immune responses. Hum. Gene Ther. 16: 634-641 (2005).
Andersson IE, Dzhambazov B, Holmdahl R, Linusson A, Kihlberg J. Probing molecular interactions within class II MHC A(q)/glycopeptide/T-cell receptor complexes associated with collagen-induced arthritis. J. Med. Chem. 50: 5627-5643 (2007). *
Andersson J, Stefanova I, Stephens GL, Shevach EM. CD4+CD25+ regulatory T cells are activated in vivo by recognition of self. Int. Immunol. 19: 557-566 (2007). *
Anfossi N, Andre P, Guia S, Falk CS, Roetynck S, Stewart CA, Breso V, Frassati C, Reviron D, Middleton D, Romagne F, Ugolini S, Vivier E. Human NK cell education by inhibitory receptors for MHC class I. Immunity 25: 331-342 (2006). *
Angel CE, George E, Ostrovsky LL, Dunbar PR. Comprehensive analysis of MHC-II expression in healthy human skin. Immunol. Cell Biol. 85: 363-369 (2007). *
Angulo P. Use of ursodeoxycholic acid in patients with liver disease. Curr. Gastroenterol. Rep. 4: 37-44 (2002).
Annacker O, Coombes JL, Malmstrom V, Uhlig HH, Bourne T, Johansson-Lindbom B, Agace WW, Parker CM, Powrie F. Essential role for CD103 in the T cell-mediated regulation of experimental colitis. J. Exp. Med. 202: 1051-1061 (2005). *
Ansari AA, Pattanapanyasat K. Chapter 33. Immunological tolerance in allo- and xenografts. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 433-449 (2007). *
Antal Z, Jarchum I, DiLorenzo TP. HLA class I supertypes in type 1 diabetic children in an urban children's hospital. Ann. N. Y. Acad. Sci. 1150: 86-89 (2008). *
Antoniou AN, Powis SJ. Pathogen evasion strategies for the major histocompatibility complex class I assembly pathway. Immunology 124: 1-12 (2008). *
Antoniou AN, Santos SG, Campbell EC, Lynch S, Arosa FA, Powis SJ. ERp57 interacts with conserved cysteine residues in the MHC class I peptide-binding groove. FEBS Lett. 581: 1988-1992 (2007). *
Antonysamy MA, Fanslow WC, Fu F, Li W, Qian S, Troutt AB, Thomson AW. Evidence for a role of IL-17 in organ allograft rejection: IL-17 promotes the functional differentiation of dendritic cell progenitors. J. Immunol. 162: 577-584 (1999). *
Antoun A, Jobson S, Cook M, Moss P, Briggs D. Ethnic variability in human leukocyte antigen-E haplotypes. Tissue Antigens 73: 39-45 (2009). *
Antunez MI, Cardoni RL. Superantigens: a particular interaction between microorganisms and the immune system. Medicina (B. Aires) 57: 608-616 (1997).
Aoki CA, Borchers AT, Li M, Flavell RA, Bowlus CL, Ansari AA, Gershwin ME. Transforming growth factor beta (TGF-beta) and autoimmunity. Autoimmun. Rev. 4: 450-459 (2005).
Aoki CA, Borchers AT, Ridgway WM, Keen CL, Ansari AA, Gershwin ME. NOD mice and autoimmunity. Autoimmun. Rev. 4: 373-379 (2005).
Aosai F, Rodriguez Pena MS, Mun HS, Fang H, Mitsunaga T, Norose K, Kang HK, Bae YS, Yano A. Toxoplasma gondii-derived heat shock protein 70 stimulates maturation of murine bone marrow-derived dendritic cells via Toll-like receptor 4. Cell Stress Chaperones 11: 13-22 (2006). *
Aoshi T, Nagata T, Suzuki M, Uchijima M, Hashimoto D, Rafiei A, Suda T, Chida K, Koide Y. Identification of HLA-A*0201-restricted T-cell epitope on MPT51 protein, a major secreted protein derived from Mycobacterium tuberculosis using MPT51 overlapping peptides screening. Infect. Immun. 76: 1565-1571 (2008). *
Apps R, Gardner L, Sharkey AM, Holmes N, Moffett A. A homodimeric complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1. Eur. J. Immunol. 37: 1924-1937 (2007). *
Apte SH, Baz A, Groves P, Kelso A, Kienzle N. Interferon-gamma and interleukin-4 reciprocally regulate CD8 expression in CD8+ T cells. Proc. Natl. Acad. Sci. U.S.A. 105: 17475-17480 (2008). *
Aptsiauri N, Carretero R, Garcia-Lora A, Real LM, Cabrera T, Garrido F. Regressing and progressing metastatic lesions: resistance to immunotherapy is predetermined by irreversible HLA class I antigen alterations. Cancer Immunol. Immunother. 57: 1727-1733 (2008).
Arakaki R, Nagaoka A, Ishimaru N, Yamada A, Yoshida S, Hayashi Y. Role of plasmacytoid dendritic cells for aberrant class II expression in exocrine glands from estrogen-deficient mice of healthy background. Am. J. Pathol. 174: 1715-1724 (2009). *
Araki M, Miyake S, Yamamura T. Synthetic glycolipid ligands for human iNKT cells as potential therapeutic agents for immunotherapy. Curr. Med. Chem. 15: 2337-2345 (2008).
Araujo MB, Leonardi LS, Leonardi MI, Boin IF, Magna LA, Donadi EA, Kraemer MH. Prospective analysis between the therapy of immunosuppressive medication and allogeneic microchimerism after liver transplantation. Transpl. Immunol. 20: 195-198 (2009).
Arbour N, Lapointe R, Saikali P, McCrea E, Regen T, Antel JP. A new clinically relevant approach to expand myelin specific T cells. J. Immunol. Methods 310: 53-61 (2006). *
Archbold JK, Macdonald WA, Gras S, Ely LK, Miles JJ, Bell MJ, Brennan RM, Beddoe T, Wilce MC, Clements CS, Purcell AW, McCluskey J, Burrows SR, Rossjohn J. Natural micropolymorphism in human leukocyte antigens provides a basis for genetic control of antigen recognition. J. Exp. Med. 206: 209-219 (2009). *
Arentz-Hansen H, Korner R, Molberg O, Quarsten H, Vader W, Kooy YM, Lundin KE, Koning F, Roepstorff P, Sollid LM, McAdam SN. The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase. J. Exp. Med. 191: 603-612 (2000). *
Arias DA, McCarty N, Lu L, Maldonado RA, Shinohara ML, Cantor H. Unexpected role of clathrin adaptor AP-1 in MHC-dependent positive selection of T cells. Proc. Natl. Acad. Sci. U.S.A. 107: 2556-2561 (2010). *
Arina A, Murillo O, Dubrot J, Azpilikueta A, Alfaro C, Perez-Gracia JL, Bendandi M, Palencia B, Hervas-Stubbs S, Melero I. Cellular liaisons of natural killer lymphocytes in immunology and immunotherapy of cancer. Expert Opin. Biol. Ther. 7: 599-615 (2007).
Arita S, Baba E, Shibata Y, Niiro H, Shimoda S, Isobe T, Kusaba H, Nakano S, Harada M. B cell activation regulates exosomal HLA production. Eur. J. Immunol. 38: 1423-1434 (2008). *
Armstrong KM, Baker BM. A comprehensive calorimetric investigation of an entropically driven T cell receptor-peptide/MHC interaction. Biophys. J. 93: 597-609 (2007). *
Armstrong KM, Piepenbrink KH, Baker BM. Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes. Biochem. J. 415: 183-196 (2008). *
Arnaboldi P, Roth-Walter F, Mayer L. Suppression of Th1 and Th17, but not Th2, responses in a CD8(+) T cell-mediated model of oral tolerance. Mucosal Immunol. 2: 427-438 (2009).
Arnaiz-Villena A, Martinez-Laso J, Serrano-Vela JI, Reguera R, Moscoso J. HLA-G polymorphism and evolution. Tissue Antigens 69 Suppl. 1: 156-159 (2007). *
Arnaiz-Villena A, Vargas-Alarcon G, Serrano-Vela JI, Reguera R, Martinez-Laso J, Silvera-Redondo C, Granados J, Moscoso J. HLA-E polymorphism in Amerindians from Mexico (Mazatecans), Colombia (Wayu) and Chile (Mapuches): evolution of MHC-E gene. Tissue Antigens 69 Suppl. 1: 132-135 (2007). *
Arneson LS, Miller J. The chondroitin sulfate form of invariant chain trimerizes with conventional invariant chain and these complexes are rapidly transported from the trans-Golgi to the cell surface. Biochem. J. 406: 97-103 (2007). *
Arnett FC. Genetic studies of human lupus in families. Int. Rev. Immunol. 19: 297-317 (2000).
Arnett FC, Bias WB, Reveille JD. Genetic studies in Sjogren's syndrome and systemic lupus erythematosus. J. Autoimmun. 2: 403-413 (1989).
Arnett FC, Gourh P, Shete S, Ahn CW, Honey R, Agarwal SK, Tan FK, McNearney T, Fischbach M, Fritzler MJ, Mayes MD, Reveille JD. Major histocompatibility complex (MHC) class II alleles, haplotypes, and epitopes which confer susceptibility or protection in the fibrosing autoimmune disease systemic sclerosis: analyses in 1300 Caucasian, African-American and Hispanic cases � Ann. Rheum. Dis. Jul 12 [Epub ahead of print] (2009).
Arnett FC, Hamilton RG, Reveille JD, Bias WB, Harley JB, Reichlin M. Genetic studies of Ro (SS-A) and La (SS-B) autoantibodies in families with systemic lupus erythematosus and primary Sjogren's syndrome. Arthritis Rheum. 32: 413-419 (1989).
Arques JL, Hautefort I, Ivory K, Bertelli E, Regoli M, Clare S, Hinton JC, Nicoletti C. Salmonella induces flagellin- and MyD88-dependent migration of bacteria-capturing dendritic cells into the gut lumen. Gastroenterology 137: 579-587.e1-e2 (2009). *
Arrenberg P, Halder R, Kumar V. Cross-regulation between distinct natural killer T cell subsets influences immune response to self and foreign antigens. J. Cell. Physiol. 218: 246-250 (2008). *
Arrieta-Aguirre I, Garcia-Etxebarria K, Jugo BM. Optimization of the MhcOvar-DRB1 gene typing. Tissue Antigens 67: 222-228 (2006). *
Arvieux C, Calmus Y, Gane P, Legendre C, Mariani P, Delelo R, Poupon R, Nordlinger B. Immunogenicity of rat hepatocytes in vivo: effect of cholestasis-induced changes in major histocompatibility complex expression. J. Hepatol. 18: 335-341 (1993).
Asai Y, Makimura Y, Ogawa T. Toll-like receptor 2-mediated dendritic cell activation by a Porphyromonas gingivalis synthetic lipopeptide. J. Med. Microbiol. 56: 459-465 (2007). *
Asano K, Matsushita T, Umeno J, Hosono N, Takahashi A, Kawaguchi T, Matsumoto T, Matsui T, Kakuta Y, Kinouchi Y, Shimosegawa T, Hosokawa M, Arimura Y, Shinomura Y, Kiyohara Y, Tsunoda T, Kamatani N, Iida M, Nakamura Y, Kubo M. A genome-wide association study identifies three new susceptibility loci for ulcerative colitis in the Japanese population. Nat. Genet. 41: 1325-1329 (2009). *
Asemissen AM, Haase D, Stevanovic S, Bauer S, Busse A, Thiel E, Rammensee HG, Keilholz U, Scheibenbogen C. Identification of an immunogenic HLA-A*0201-binding T-cell epitope of the transcription factor PAX2. J. Immunother. 32: 370-375 (2009).
Ashley CW, Baecher-Allan C. Cutting edge: responder T cells regulate human DR+ effector regulatory T cell activity via granzyme B. J. Immunol. 183: 4843-4847 (2009).
Ashman RF, Schaffer FM, Kemp JD, Yokoyama WM, Zhu ZB, Cooper MD, Volanakis JE. Genetic and immunologic analysis of a family containing five patients with common-variable immune deficiency or selective IgA deficiency. J. Clin. Immunol. 12: 406-414 (1992).
Ashour HM, Niederkorn JY. Peripheral tolerance via the anterior chamber of the eye: role of B cells in MHC class I and II antigen presentation. J. Immunol. 176: 5950-5957 (2006). *
Aslam R, Kim M, Speck ER, Seetanah AC, Molinski S, Freedman J, Semple JW. Platelet and red blood cell phagocytosis kinetics are differentially controlled by phosphatase activity within mononuclear cells. Transfusion 47: 2161-2168 (2007).
Assounga AG, Warner CM. Memory lymphocytes of young and old C57BL/6 mice express high levels of class I major histocompatibility complex (H-2 Kb) protein. Growth Dev. Aging 69: 59-66 (2005).
Astrakhan A, Ochs HD, Rawlings DJ. Wiskott-Aldrich syndrome protein is required for homeostasis and function of invariant NKT cells. J. Immunol. 182: 7370-7380 (2009).
Asumalahti K, Ameen M, Suomela S, Hagforsen E, Michaelsson G, Evans J, Munro M, Veal C, Allen M, Leman J, David Burden A, Kirby B, Connolly M, Griffiths CE, Trembath RC, Kere J, Saarialho-Kere U, Barker JN. Genetic analysis of PSORS1 distinguishes guttate psoriasis and palmoplantar pustulosis. J. Invest. Dermatol. 120: 627-632 (2003). *
Asumalahti K, Veal C, Laitinen T, Suomela S, Allen M, Elomaa O, Moser M, de Cid R, Ripatti S, Vorechovsky I, Marcusson JA, Nakagawa H, Lazaro C, Estivill X, Capon F, Novelli G, Saarialho-Kere U, Barker J, Trembath R, Kere J; Psoriasis Consortium. Coding haplotype analysis supports HCR as the putative susceptibility gene for psoriasis at the MHC PSORS1 locus. Hum. Mol. Genet. 11: 589-597 (2002). *
Atassi MZ, Oshima M, Deitiker P. On the initial trigger of myasthenia gravis and suppression of the disease by antibodies against the MHC peptide region involved in the presentation of a pathogenic T-cell epitope. Crit. Rev. Immunol. 21: 1-27 (2001).
Ates O, Dalyan L, Hatemi G, Hamuryudan V, Topal-Sarikaya A. Genetic susceptibility to Behcet's syndrome is associated with NRAMP1 (SLC11A1) polymorphism in Turkish patients. Rheumatol. Int. 29: 787-791 (2009). *
Ates O, Musellim B, Ongen G, Topal-Sarikaya A. NRAMP1 (SLC11A1): a plausible candidate gene for systemic sclerosis (SSc) with interstitial lung involvement. J. Clin. Immunol. 28: 73-77 (2008). *
Atkins D, Breuckmann A, Schmahl GE, Binner P, Ferrone S, Krummenauer F, Storkel S, Seliger B. MHC class I antigen processing pathway defects, ras mutations and disease stage in colorectal carcinoma. Int. J. Cancer 109: 265-273 (2004). *
Atkinson SH, Rockett KA, Morgan G, Bejon PA, Sirugo G, O'Connell MA, Hanchard N, Kwiatkowski D, Prentice AM. Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African children. Blood 112: 4276-4283 (2008). *
Auerbach A, Fanburg-Smith JC, Wang G, Rushing EJ. Focal myositis: a clinicopathologic study of 115 cases of an intramuscular mass-like reactive process. Am. J. Surg. Pathol. Apr 9 [Epub ahead of print] (2009).
Augello A, Tasso R, Negrini SM, Cancedda R, Pennesi G. Cell therapy using allogeneic bone marrow mesenchymal stem cells prevents tissue damage in collagen-induced arthritis. Arthritis Rheum. 56: 1175-1186 (2007). *
Avci FY, Kasper DL. How bacterial carbohydratesinfluence the adaptive immune aystem. Annu. Rev. Immunol. Nov 10 [Epub ahead of print] (2009). *
Avila-Portillo LM, Vargas-Alarcon G, Andrade F, Alarcon-Segovia D, Granados J. Linkage disequilibrium of HLA-DR3 and HLA-DR4 with HLA-B alleles in Mexican patients with rheumatoid arthritis. Clin. Exp. Rheumatol. 12: 497-502 (1994).
Axelsson-Robertson R, Weichold F, Sizemore D, Wulf M, Skeiky YA, Sadoff J, Maeurer MJ. Extensive major histocompatibility complex class I binding promiscuity for Mycobacterium tuberculosis TB10.4 peptides and immune dominance of human leucocyte antigen (HLA)-B*0702 and HLA-B*0801 alleles in TB10.4 CD8(+) T-cell responses. Immunology Dec 14 [Epub ahead of print] (2009). *
Axtner J, Sommer S. Gene duplication, allelic diversity, selection processes and adaptive value of MHC class II DRB genes of the bank vole, Clethrionomys glareolus. Immunogenetics 59: 417-426 (2007). *
Ayadi H, Kacem HH, Rebai A, Farid NR. The genetics of autoimmune thyroid disease. Trends Endocrinol. Metab. 15: 234-239 (2004). *
Ayres RC, Neuberger JM, Shaw J, Joplin R, Adams DH. Intercellular adhesion molecule-1 and MHC antigens on human intrahepatic bile duct cells: effect of pro-inflammatory cytokines. Gut 34: 1245-1249 (1993). *
Azar GA, Sekaly RP, Thibodeau J. A defective viral superantigen-presenting phenotype in HLA-DR transfectants is corrected by CIITA. J. Immunol. 174: 7548-7557 (2005). *
Azizah MR, Kuak SH, Ainol SS, Rahim MN, Normaznah Y, Norella K. Association of the tumor necrosis factor alpha gene polymorphism with susceptibility and clinical-immunological findings of systemic lupus erythematosus. Asian Pac. J. Allergy Immunol. 22: 159-163 (2004).
Baccala R, Kono DH, Theofilopoulos AN. Interferons as pathogenic effectors in autoimmunity. Immunol. Rev. 204: 9-26 (2005).
Baccala R, Theofilopoulos AN. The new paradigm of T-cell homeostatic proliferation-induced autoimmunity. Trends Immunol. 26: 5-8 (2005). *
Bach JF. Infections and autoimmune diseases. J. Autoimmun. 25: S74-S80 (2005).
Bachmaier K, Penninger JM. Chlamydia and antigenic mimicry. Curr. Top. Microbiol. Immunol. 296: 153-163 (2005).
Back J, Malchiodi EL, Cho S, Scarpellino L, Schneider P, Kerzic MC, Mariuzza RA, Held W. Distinct conformations of Ly49 natural killer cell receptors mediate MHC class I recognition in trans and cis. Immunity 31: 598-608 (2009). *
Backer R, van Leeuwen F, Kraal G, den Haan JM. CD8(-) dendritic cells preferentially cross-present Saccharomyces cerevisiae antigens. Eur. J. Immunol. 38: 370-380 (2008). *
Backstrom E, Kristensson K, Ljunggren HG. Activation of natural killer cells: underlying molecular mechanisms revealed. Scand. J. Immunol. 60: 14-22 (2004). *
Badenhoop K, Boehm BO. Genetic susceptibility and immunological synapse in type 1 diabetes and thyroid autoimmune disease. Exp. Clin. Endocrinol. Diabetes 112: 407-415 (2004).
Badenhoop K, Donner H, Pani M, Rau H, Siegmund T, Braun J. Genetic susceptibility to type 1 diabetes: clinical and molecular heterogeneity of IDDM1 and IDDM12 in a German population. Exp. Clin. Endocrinol. Diabetes 107 Suppl. 3: S89-S92 (1999).
Badenhoop K, Kahles H, Seidl C, Kordonouri O, Lopez ER, Walter M, Rosinger S, Ziegler A, Bohm BO; Diabetes Genetics Consortium. MHC-environment interactions leading to type 1 diabetes: feasibility of an analysis of HLA DR-DQ alleles in relation to manifestation periods and dates of birth. Diabetes Obes. Metab. 11 Suppl. 1: 88-91 (2009). *
Badou A, Saoudi A, Dietrich G, Druet E, Druet P, Pelletier L. Mercuric chloride-induced autoimmunity. Curr. Protoc. Immunol. Chapter 15: Unit 15.15 (2001).
Baecher-Allan C, Wolf E, Hafler DA. MHC class II expression identifies functionally distinct human regulatory T cells. J. Immunol. 176: 4622-4631 (2006). *
Baeten D, Steenbakkers PG, Rijnders AM, Boots AM, Veys EM, De Keyser F. Detection of major histocompatibility complex/human cartilage gp-39 complexes in rheumatoid arthritis synovitis as a specific and independent histologic marker. Arthritis Rheum. 50: 444-451 (2004). *
Bagley J, Tian C, Iacomini J. Prevention of type 1 diabetes in NOD mice by genetic engineering of hematopoietic stem cells. Methods Mol. Biol. 433: 277-286 (2008).
Bai H, Cheng J, Gao X, Joyee AG, Fan Y, Wang S, Jiao L, Yao Z, Yang X. IL-17/Th17 promotes type 1 T cell immunity against pulmonary intracellular bacterial infection through modulating dendritic cell function. J. Immunol. 183: 5886-5895 (2009). *
Bailey JR, Williams TM, Siliciano RF, Blankson JN. Maintenance of viral suppression in HIV-1-infected HLA-B*57+ elite suppressors despite CTL escape mutations. J. Exp. Med. 203: 1357-1369 (2006). *
Bakacs T, Mehrishi JN, Szabados T, Varga L, Szabo M, Tusnady G. T cells survey the stability of the self: a testable hypothesis on the homeostatic role of TCR-MHC interactions. Int. Arch. Allergy Immunol. 144: 171-182 (2007).
Baker ML, Melman SD, Huntley J, Miller RD. Evolution of the opossum major histocompatibility complex: evidence for diverse alternative splice patterns and low polymorphism among class I genes. Immunology 128: e418-e431 (2009).
Baker MP, Jones TD. Identification and removal of immunogenicity in therapeutic proteins. Curr. Opin. Drug Discov. Devel. 10: 219-227 (2007).
Bakker AH, Hoppes R, Linnemann C, Toebes M, Rodenko B, Berkers CR, Hadrup SR, van Esch WJ, Heemskerk MH, Ovaa H, Schumacher TN. Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7. Proc. Natl. Acad. Sci. U.S.A. 105: 3825-3830 (2008). *
Balato A, Unutmaz D, Gaspari AA. Natural killer T cells: an unconventional T-cell subset with diverse effector and regulatory functions. J. Invest. Dermatol. 129: 1628-1642 (2009). *
Ball LM, Bernardo ME, Locatelli F, Egeler RM. Potential role of mesenchymal stromal cells in pediatric hematopoietic SCT. Bone Marrow Transplant. 42 Suppl, 2: S60-S66 (2008).
Balladares S, Alaez C, Pujol J, Duran C, Navarro JL, Gorodezky C. Distribution of TAP gene polymorphisms and extended MHC haplotypes in Mexican Mestizos and in Seri Indians from northwest Mexico. Genes Immun. 3: 78-85 (2002). *
Ballardini G, Mirakian R, Bianchi FB, Pisi E, Doniach D, Bottazzo GF. Aberrant expression of HLA-DR antigens on bileduct epithelium in primary biliary cirrhosis: relevance to pathogenesis. Lancet 2: 1009-1013 (1984).
Ballingall KT, Miltiadou D, Chai ZW, McLean K, Rocchi M, Yaga R, McKeever DJ. Genetic and proteomic analysis of the MHC class I repertoire from four ovine haplotypes. Immunogenetics 60: 177-184 (2008). *
Balog A, Gal J, Gyulai Z, Zsilak S, Mandi Y. Tumour necrosis factor-alpha and heat-shock protein 70-2 gene polymorphisms in a family with rheumatoid arthritis. Acta Microbiol. Immunol. Hung. 51: 263-269 (2004).
Banerjee S, Michetti P. Strategies for developing a Helicobacter pylori vaccine. Curr. Opin. Gastroenterol. 15: 557 (1999).
Barahmani N, de Andrade M, Slusser JP, Zhang Q, Duvic M. Major histocompatibility complex class I chain-related gene a polymorphisms and extended haplotypes are associated with familial alopecia areata. J. Invest. Dermatol. 126: 74-78 (2006). *
Baran W, Szepietowski JC, Mazur G, Baran E. A - 308 promoter polymorphism of tumor necrosis factor alpha gene does not associate with the susceptibility to psoriasis vulgaris. No difference either between psoriasis type I and type II patients. Acta Dermatovenerol. Alp. Panonica Adriat. 15: 113-118 (2006). *
Baranzini SE. The genetics of autoimmune diseases: a networked perspective. Curr. Opin. Immunol. 21: 596-605 (2009). *
Barcellos LF, May SL, Ramsay PP, Quach HL, Lane JA, Nititham J, Noble JA, Taylor KE, Quach DL, Chung SA, Kelly JA, Moser KL, Behrens TW, Seldin MF, Thomson G, Harley JB, Gaffney PM, Criswell LA. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. PLoS Genet. 5: e1000696 (2009). *
Barcellos LF, Ramsay PP, Caillier SJ, Sawcer S, Haines J, Schmidt S, Pericak-Vance M, Compston DA, Gabatto P, Hauser SL, Oksenberg JR. Genetic variation in nitric oxide synthase 2A (NOS2A) and risk for multiple sclerosis. Genes Immun. 9: 493-500 (2008). *
Barcellos LF, Sawcer S, Ramsay PP, Baranzini SE, Thomson G, Briggs F, Cree BC, Begovich AB, Villoslada P, Montalban X, Ucelli A, Savettieri G, Lincoln RL, Deloa C, Haines JL, Pericak-Vance MA, Compston A, Hauser SL, Oksenberg JR. Heterogeneity at the HLA-DRB1 locus and risk for multiple sclerosis. Hum. Mol. Genet. 15: 2813-2824 (2006). *
Barker JM. Type 1 diabetes associated autoimmunity: natural history, genetic associations and screening. J. Clin. Endocrinol. Metab. 91: 1210-1217 (2006). *
Barker JN. Genetic aspects of psoriasis. Clin. Exp. Dermatol. 26: 321-325 (2001). *
Barland P. Antibodies to citrullinated peptides: current role in diagnosis, prognosis, and pathogenesis of rheumatoid arthritis. New Developments in Rheumatic Diseases 1: 6-9 (2004). *
Barlow AK, He X, Janeway C Jr. Exogenously provided peptides of a self-antigen can be processed into forms that are recognized by self-T cells. J. Exp. Med. 187: 1403-1415 (1998). *
Barnes BH, Tucker RM, Wehrmann F, Mack DG, Ueno Y, Mack CL. Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia. Liver Int. 29: 1253-1261 (2009). *
Barnetche T, Constantin A, Gourraud PA, Abbal M, Garnier JG, Cantagrel A, Cambon-Thomsen A. Microsatellite typing of the human leucocyte antigen region: analytical approach and contribution to rheumatoid arthritis immunogenetic studies. Tissue Antigens 68: 390-398 (2006). *
Barral AM, Thomas HE, Ling EM, Darwiche R, Rodrigo E, Christen U, Ejrnaes M, Wolfe T, Kay TW, von Herrath MG. SOCS-1 protects from virally-induced CD8 T cell mediated type 1 diabetes. J. Autoimmun. 27: 166-173 (2006).
Barral DC, Brenner MB. CD1 antigen presentation: how it works. Nat. Rev. Immunol. 7: 929-941 (2007). *
Bartee E, McCormack A, Fruh K. Quantitative membrane proteomics reveals new cellular targets of viral immune modulators. PLoS Pathog. 2: e107 (2006). *
Barten R, Torkar M, Haude A, Trowsdale J, Wilson MJ. Divergent and convergent evolution of NK-cell receptors. Trends Immunol. 22: 52-57 (2001). *
Barton A, Eyre S, Myerscough A, Brintnell B, Ward D, Ollier WE, Lorentzen JC, Klareskog L, Silman A, John S, Worthington J; Arthritis Rheumatism Campaign National Repository. High resolution linkage and association mapping identifies a novel rheumatoid arthritis susceptibility locus homologous to one linked to two rat models of inflammatory arthritis. Hum. Mol. Genet. 10: 1901-1906 (2001). *
Bartsocas CS, Gerasimidi-Vazeou A. Genetics of type 1 diabetes mellitus. Pediatr. Endocrinol. Rev. 3 Suppl. 3: 508-513 (2006).
Baschal EE, Aly TA, Jasinski JM, Steck AK, Johnson KN, Noble JA, Erlich HA, Eisenbarth GS; Diabetes Genetics Consortium. The frequent and conserved DR3-B8-A1 extended haplotype confers less diabetes risk than other DR3 haplotypes. Diabetes Obes. Metab. 11 Suppl. 1: 25-30 (2009). *
Baschal EE, Aly TA, Jasinski JM, Steck AK, Noble JA, Erlich HA, Eisenbarth GS; the Type 1 Diabetes Genetics Consortium. Defining multiple common "completely" conserved major histocompatibility complex SNP haplotypes. Clin. Immunol. 132: 203-214 (2009). *
Baschal EE, Eisenbarth GS. Extreme genetic risk for type 1A diabetes in the post-genome era. J. Autoimmun. 31: 1-6 (2008).
Bashirova AA, Martin MP, McVicar DW, Carrington M. The killer immunoglobulin-like receptor gene cluster: tuning the genome for defense. Annu. Rev. Genomics Hum. Genet. 7: 277-300 (2006). *
Basler M, Lauer C, Beck U, Groettrup M. The proteasome inhibitor bortezomib enhances the susceptibility to viral infection. J. Immunol. 183: 6145-6150 (2009).
Bassaganya-Riera J, Misyak S, Guri AJ, Hontecillas R. PPAR gamma is highly expressed in F4/80(hi) adipose tissue macrophages and dampens adipose-tissue inflammation. Cell. Immunol. 258: 138-146 (2009). *
Basta S, Alatery A. The cross-priming pathway: a portrait of an intricate immune system. Scand. J. Immunol. 65: 311-319 (2007). *
Basten A, Fazekas de St Groth B. Special regulatory T-cell review: T-cell dependent suppression revisited. Immunology 123: 33-39 (2008). *
Basu R, Roy S, Walden P. HLA class I-restricted T cell epitopes of the kinetoplastid membrane protein-11 presented by Leishmania donovani-infected human macrophages. J. Infect. Dis. 195: 1373-1380 (2007). *
Bata-Csorgo Z, Hammerberg C, Voorhees JJ, Cooper KD. Intralesional T-lymphocyte activation as a mediator of psoriatic epidermal hyperplasia. J. Invest. Dermatol. 105: 89S-94S (1995).
Bauer J, Elger CE, Hans VH, Schramm J, Urbach H, Lassmann H, Bien CG. Astrocytes are a specific immunological target in Rasmussen's encephalitis. Ann. Neurol. 62: 67-80 (2007).
Bauer K, Yu X, Wernhoff P, Koczan D, Thiesen HJ, Ibrahim SM. Identification of new quantitative trait loci in mice with collagen-induced arthritis. Arthritis Rheum. 50: 3721-3728 (2004). *
Bauer S, Groh V, Wu J, Steinle A, Phillips JH, Lanier LL, Spies T. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 285: 727-729 (1999). *
Baughman RP, Lower EE, du Bois RM. Sarcoidosis. Lancet 361: 1111-1118 (2003). *
Baum H. Mitochondrial antigens, molecular mimicry and autoimmune disease. Biochim. Biophys. Acta 1271: 111-121 (1995).
Baum H, Staines NA. MHC-derived peptides and the CD4+ T-cell repertoire: implications for autoimmune disease. Cytokines Cell Mol. Ther. 3: 115-125 (1997).
Baxter AG. The origin and application of experimental autoimmune encephalomyelitis. Nat. Rev. Immunol. 7: 904-912 (2007). *
Bayer AL, Jones M, Chirinos J, de Armas L, Schreiber TH, Malek TR, Levy RB. Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment following experimental HCT. Blood 113: 733-743 (2009). *
Bayley JP, Ottenhoff TH, Verweij CL. Is there a future for TNF promoter polymorphisms? Genes Immun. 5: 315-329 (2004). *
Bayry J, Triebel F, Kaveri SV, Tough DF. Human dendritic cells acquire a semimature phenotype and lymph node homing potential through interaction with CD4+CD25+ regulatory T cells. J. Immunol. 178: 4184-4193 (2007). *
Beaumier CM, Harris LD, Goldstein S, Klatt NR, Whitted S, McGinty J, Apetrei C, Pandrea I, Hirsch VM, Brenchley JM. CD4 downregulation by memory CD4(+) T cells in vivo renders African green monkeys resistant to progressive SIVagm infection. Nat. Med. 15: 879-885 (2009). *
Bebo BF Jr, Dehghani B, Foster S, Kurniawan A, Lopez FJ, Sherman LS. Treatment with selective estrogen receptor modulators regulates myelin specific T-cells and suppresses experimental autoimmune encephalomyelitis. Glia 57: 777-790 (2008).
Becher B, Bechmann I, Greter M. Antigen presentation in autoimmunity and CNS inflammation: how T lymphocytes recognize the brain. J. Mol. Med. 84: 532-543 (2006). *
Beck S, Trowsdale J. The human major histocompatability complex: lessons from the DNA sequence. Annu. Rev. Genomics Hum. Genet. 1: 117-137 (2000). *
Becker KG, Simon RM, Bailey-Wilson JE, Freidlin B, Biddison WE, McFarland HF, Trent JM. Clustering of non-major histocompatibility complex susceptibility candidate loci in human autoimmune diseases. Proc. Natl. Acad. Sci. U.S.A. 95: 9979-9984 (1998). *
Beddoe T, Chen Z, Clements CS, Ely LK, Bushell SR, Vivian JP, Kjer-Nielsen L, Pang SS, Dunstone MA, Liu YC, Macdonald WA, Perugini MA, Wilce MC, Burrows SR, Purcell AW, Tiganis T, Bottomley SP, McCluskey J, Rossjohn J. Antigen ligation triggers a conformational change within the constant domain of the alphabeta T cell receptor. Immunity 30: 777-788 (2009). *
Bedford PA, Todorovic V, Westcott ED, Windsor AC, English NR, Al-Hassi HO, Raju KS, Mills S, Knight SC. Adipose tissue of human omentum is a major source of dendritic cells, which lose MHC class II and stimulatory function in Crohn's disease. J. Leukoc. Biol. 80: 546-554 (2006). *
Bedoui S, Whitney PG, Waithman J, Eidsmo L, Wakim L, Caminschi I, Allan RS, Wojtasiak M, Shortman K, Carbone FR, Brooks AG, Heath WR. Cross-presentation of viral and self antigens by skin-derived CD103(+) dendritic cells. Nat. Immunol. 10: 488-495 (2009). *
Begum D, Umemura M, Yahagi A, Okamoto Y, Hamada S, Oshiro K, Matsuzaki G. Accelerated induction of mycobacterial antigen-specific CD8(+) T cells in the Mycobacterium tuberculosis-infected lung by subcutaneous vaccination with Mycobacterium bovis bacille Calmette-Guerin. Immunology 128: 556-563 (2009). *
Behboudi S, Boswell S, Williams R. Cell-mediated immune responses to alpha-fetoprotein and other antigens in hepatocellular carcinoma. Liver Int. Dec 22 [Epub ahead of print] (2009). *
Beilhack GF, Landa RR, Masek MA, Shizuru JA. Prevention of type 1 diabetes with major histocompatibility complex-compatible and nonmarrow ablative hematopoietic stem cell transplants. Diabetes 54: 1770-1779 (2005). *
Beissbarth T, Tye-Din JA, Smyth GK, Speed TP, Anderson RP. A systematic approach for comprehensive T-cell epitope discovery using peptide libraries. Bioinformatics 21: i29-i37 (2005). *
Bel Hadj Jrad B, Chatti A, Laatiri A, Ahmed SB, Romdhane A, Ajimi S, Chouchane L. Tumor necrosis factor promoter gene polymorphism associated with increased susceptibility to non-Hodgkin's lymphomas. Eur. J. Haematol. 78: 117-122 (2007). *
Belanger S, Tai LH, Anderson SK, Makrigiannis AP. Ly49 cluster sequence analysis in a mouse model of diabetes: an expanded repertoire of activating receptors in the NOD genome. Genes Immun. 9: 509-521 (2008). *
Belic D, Ristic-Nikolic S, Damjan S, Ratkov I, Ceke M. Heredity of psoriasis. Med. Pregl. 57: 171-174 (2004).
Belizaire R, Unanue ER. Targeting proteins to distinct subcellular compartments reveals unique requirements for MHC class I and II presentation. Proc. Natl. Acad. Sci. U.S.A. 106: 17463-17468 (2009). *
Bell JJ, Divekar RD, Ellis JS, Cascio JA, Haymaker CL, Jain R, Tartar DM, Hoeman CM, Hardaway JC, Zaghouani H. In trans T cell tolerance diminishes autoantibody responses and exacerbates experimental allergic encephalomyelitis. J. Immunol. 180: 1508-1516 (2008). *
Bellamy R. Susceptibility to mycobacterial infections: the importance of host genetics. Genes Immun. 4: 4-11 (2003). *
Bellou A, Finn PW. Costimulation: critical pathways in the immunologic regulation of asthma. Curr. Allergy Asthma Rep. 5: 149-154 (2005).
Belov K, Deakin JE, Papenfuss AT, Baker ML, Melman SD, Siddle HV, Gouin N, Goode DL, Sargeant TJ, Robinson MD, Wakefield MJ, Mahony S, Cross JG, Benos PV, Samollow PB, Speed TP, Graves JA, Miller RD. Reconstructing an ancestral mammalian immune supercomplex from a marsupial major histocompatibility complex. PLoS Biol. 4: e46 (2006). *
Ben Radhia K, Ayed-Jendoubi S, Sfar I, Ben Romdhane T, Makhlouf M, Gorgi Y, Ayed K. Distribution of HLA-B*27 subtypes in Tunisians and their association with ankylosing spondylitis. Joint Bone Spine 75: 172-175 (2008). *
Benacerraf B. Role of MHC gene products in immune regulation. Science 212: 1229-1238 (1981). *
Bendix I, Pfueller CF, Leuenberger T, Glezeva N, Siffrin V, Muller Y, Prozorovski T, Hansen W, Schulze-Topphoff U, Loddenkemper C, Zipp F, Waiczies S. MAPK3 deficiency drives autoimmunity via dendritic cell arming. Eur. J. Immunol. Feb 23 [Epub ahead of print] (2010).
Benedict CA, Loewendorf A, Garcia Z, Blazar BR, Janssen EM. Dendritic cell programming by cytomegalovirus stunts naive T cell responses via the PD-L1/PD-1 pathway. J. Immunol. 180: 4836-4847 (2008). *
Benghiat FS, Craciun L, De Wilde V, Dernies T, Kubjak C, Lhomme F, Goldman M, Le Moine A. IL-17 production elicited by allo-major histocompatibility complex class II recognition depends on CD25posCD4pos T cells. Transplantation 85: 943-949 (2008).
Benichou G, Kant CD, Madsen J, Tocco G. Modulation of alloreactivity to MHC-derived peptides and transplantation tolerance. Front. Biosci. 12: 4239-4247 (2007).
Benito C, Romero JP, Tolon RM, Clemente D, Docagne F, Hillard CJ, Guaza C, Romero J. Cannabinoid CB1 and CB2 receptors and fatty acid amide hydrolase are specific markers of plaque cell subtypes in human multiple sclerosis. J. Neurosci. 27: 2396-2402 (2007).
Bennetts BH, Teutsch SM, Buhler MM, Heard RN, Stewart GJ. HLA-DMB gene and HLA-DRA promoter region polymorphisms in Australian multiple sclerosis patients. Hum. Immunol. 60: 886-893 (1999).
Bennetts BH, Teutsch SM, Heard RN, Dunckley H, Stewart GJ. TAP2 polymorphisms in Australian multiple sclerosis patients. J. Neuroimmunol. 59: 113-121 (1995).
Benseler V, McCaughan GW, Schlitt HJ, Bishop GA, Bowen DG, Bertolino P. The liver: a special case in transplantation tolerance. Semin. Liver Dis. 27: 194-213 (2007).
Benson JM, Pokorny AJ, Rhule-Smith A, Wenner CA, Kandhi V, Cech NB, Shepherd DM. Echinacea pupurea extracts modulate murine dendritic cell fate and function. Food Chem. Toxicol. Feb 8 [Epub ahead of print] (2010). *
Benvenga S, Santarpia L, Trimarchi F, Guarneri F. Human thyroid autoantigens and proteins of Yersinia and Borrelia share amino acid sequence homology that includes binding motifs to HLA-DR molecules and T-cell receptor. Thyroid 16: 225-236 (2006).
Berditchevski F, Odintsova E. Tetraspanins as regulators of protein trafficking. Traffic 8: 89-96 (2007). *
Berdowska I. Cysteine proteases as disease markers. Clin. Chim. Acta 342: 41-69 (2004). *
Berg L, Ronnelid J, Sanjeevi CB, Lampa J, Klareskog L. Interferon-gamma production in response to in vitro stimulation with collagen type II in rheumatoid arthritis is associated with HLA-DRB1(*)0401 and HLA-DQ8. Arthritis Res. 2: 75-84 (2000). *
Berg PA, Klein R. Immunology of primary biliary cirrhosis. Baillieres Clin. Gastroenterol. 1: 675-706 (1987).
Bergoffen J, Zmijewski CM, Fischbeck KH. Familial autoimmune myasthenia gravis. Neurology 44: 551-554 (1994).
Bergseng E, Xia J, Kim CY, Khosla C, Sollid LM. Main chain hydrogen bond interactions in the binding of proline-rich gluten peptides to the celiac disease associated HLA-DQ2 molecule. J. Biol. Chem. 280: 21791-21796 (2005). *
Bernstein JM, Anon JB, Rontal M, Conroy J, Wang C, Sucheston L. Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis. Laryngoscope 119: 1258-1264 (2009).
Bertelsen V, Breen K, Sandvig K, Stang E, Madshus IH. The Cbl-interacting protein TULA inhibits dynamin-dependent endocytosis. Exp. Cell Res. 313: 1696-1709 (2007). *
Berthelot L, Laplaud DA, Pettre S, Ballet C, Michel L, Hillion S, Braudeau C, Connan F, Lefrere F, Wiertlewski S, Guillet JG, Brouard S, Choppin J, Soulillou JP. Blood CD8+ T cell responses against myelin determinants in multiple sclerosis and healthy individuals. Eur. J. Immunol. 38: 1889-1899 (2008). *
Bertolino P, Bowen DG, Zen M, Holz L, Davis T, McCaughan GW. Hepatocytes as targets of autoreactivity. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, p. 33 (2004). *
Bertrams J. The HLA association of insulin-dependent (type I) diabetes mellitus. Behring Inst. Mitt. 75: 89-99 (1984).
Besin G, Gaudreau S, Menard M, Guindi C, Dupuis G, Amrani A. Thymic stromal lymphopoietin and thymic stromal lymphopoietin-conditioned dendritic cells induce regulatory T-cell differentiation and protection of NOD mice against diabetes. Diabetes 57: 2107-2117 (2008). *
Besold K, Frankenberg N, Pepperl-Klindworth S, Kuball J, Theobald M, Hahn G, Plachter B. Processing and MHC class I presentation of human cytomegalovirus pp65-derived peptides persist despite gpUS2-11-mediated immune evasion. J. Gen. Virol. 88: 1429-1439 (2007). *
Betser-Cohen G, Katz G, Gonen-Gross T, Stern N, Arnon TI, Achdout H, Gazit R, Mandelboim O. Reduced KIR2DL1 recognition of MHC class I molecules presenting phosphorylated peptides. J. Immunol. 176: 6762-6769 (2006). *
Bettinotti MP, Hartung K, Deicher H, Messer G, Keller E, Weiss EH, Albert ED. Polymorphism of the tumor necrosis factor beta gene in systemic lupus erythematosus: TNFB-MHC haplotypes. Immunogenetics 37: 449-454 (1993).
Betz S, Kaser A, Nagaishi T, Yoshida M, Hussain M, vander Lugt B, Exley M, Blumberg RS. Lipids and IBD: microsomal triglyceride transfer protein - the new dimension? Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 23 (2005). *
Bevan S, Popat S, Braegger CP, Busch A, O'Donoghue D, Falth-Magnusson K, Ferguson A, Godkin A, Hogberg L, Holmes G, Hosie KB, Howdle PD, Jenkins H, Jewell D, Johnston S, Kennedy NP, Kerr G, Kumar P, Logan RF, Love AH, Marsh M, Mulder CJ, Sjoberg K, et al. Contribution of the MHC region to the familial risk of coeliac disease. J. Med. Genet. 36: 687-690 (1999). *
Bevan S, Popat S, Houlston RS. Relative power of linkage and transmission disequilibrium test strategies to detect non-HLA linked coeliac disease susceptibility genes. Gut 45: 668-671 (1999). *
Beverley PC. Primer: making sense of T-cell memory. Nat. Clin. Pract. Rheumatol. 4: 43-49 (2008). *
Bewry NN, Bolick SC, Wright KL, Harton JA. GTP-dependent recruitment of CIITA to the class II major histocompatibility complex promoter. J. Biol. Chem. 282: 26178-26184 (2007). *
Bhat KP, Turner JD, Myers SE, Cape AD, Ting JP, Greer SF. The 19S proteasome ATPase Sug1 plays a critical role in regulating MHC class II transcription. Mol. Immunol. 45: 2214-2224 (2008). *
Bickston SJ, Comerford LW, Cominelli F. Future therapies for inflammatory bowel disease. Curr. Gastroenterol. Rep. 5: 518-523 (2003).
Bikoff EK, Kenty G, Van Kaer L. Distinct peptide loading pathways for MHC class II molecules associated with alternative Ii chain isoforms. J. Immunol. 160: 3101-3110 (1998). *
Bilbao JR, Calvo B, Aransay AM, Martin-Pagola A, Perez de Nanclares G, Aly TA, Rica I, Vitoria JC, Gaztambide S, Noble J, Fain PR, Awdeh ZL, Alper CA, Castano L. Conserved extended haplotypes discriminate HLA-DR3-homozygous Basque patients with type 1 diabetes mellitus and celiac disease. Genes Immun. 7: 550-554 (2006). *
Bilbao JR, Martin-Pagola A, Vitoria JC, Zubillaga P, Ortiz L, Castano L. HLA-DRB1 and MHC class 1 chain-related A haplotypes in Basque families with celiac disease. Tissue Antigens 60: 71-76 (2002). *
Bishof NA, Welch TR, Beischel LS, Carson D, Donnelly PA. DP polymorphism in HLA-A1,-B8,-DR3 extended haplotypes associated with membranoproliferative glomerulonephritis and systemic lupus erythematosus. Pediatr. Nephrol. 7: 243-246 (1993).
Bisping G, Lugering N, Lutke-Brintrup S, Pauels HG, Schurmann G, Domschke W, Kucharzik T. Patients with inflammatory bowel disease (IBD) reveal increased induction capacity of intracellular interferon-gamma (IFN-gamma) in peripheral CD8+ lymphocytes co-cultured with intestinal epithelial cells. Clin. Exp. Immunol. 123: 15-22 (2001). *
Bittencourt PL, Palacios SA, Farias AQ, Abrantes-Lemos CP, Cancado EL, Carrilho FJ, Laudanna AA, Kalil J, Goldberg AC. Analysis of major histocompatibility complex and CTLA-4 alleles in Brazilian patients with primary biliary cirrhosis. J. Gastroenterol. Hepatol. 18: 1061-1066 (2003). *
Bitti PP, Murgia BS, Ticca A, Ferrai R, Musu L, Piras ML, Puledda E, Campo S, Durando S, Montomoli C, Clayton DG, Mander AP, Bernardinelli L. Association between the ancestral haplotype HLA A30B18DR3 and multiple sclerosis in central Sardinia. Genet. Epidemiol. 20: 271-283 (2001).
Bjorses P, Pelto-Huikko M, Kaukonen J, Aaltonen J, Peltonen L, Ulmanen I. Localization of the APECED protein in distinct nuclear structures. Hum. Mol. Genet. 8: 259-266 (1999). *
Blach-Olszewska Z. Innate immunity: cells, receptors, and signaling pathways. Arch. Immunol. Ther. Exp. (Warsz.) 53: 245-253 (2005).
Blache C, Adriouch S, Calbo S, Drouot L, Dulauroy S, Arnoult C, Le Corre S, Six A, Seman M, Boyer O. Cutting edge: CD4-independent development of functional FoxP3+ regulatory T cells. J. Immunol. 183: 4182-4186 (2009).
Black KE, Murray JA, David CS. HLA-DQ determines the response to exogenous wheat proteins: a model of gluten sensitivity in transgenic knockout mice. J. Immunol. 169: 5595-600 (2002). *
Black MH, Watanabe RM. A principal-components-based clustering method to identify multiple variants associated with rheumatoid arthritis and arthritis-related autoantibodies. BMC Proc. 3 Suppl. 7: S129 (2009). *
Blanchard N, Kanaseki T, Escobar H, Delebecque F, Nagarajan NA, Reyes-Vargas E, Crockett DK, Raulet DH, Delgado JC, Shastri N. Endoplasmic reticulum aminopeptidase associated with antigen processing defines the composition and structure of MHC class I peptide repertoire in normal and virus-infected cells. J. Immunol. Feb 19 [Epub ahead of print] (2010).
Blanchard N, Shastri N. Cross-presentation of peptides from intracellular pathogens by MHC class I molecules. Ann. N. Y. Acad. Sci. 1183: 237-250 (2010). *
Blanchard N, Shastri N. Coping with loss of perfection in the MHC class I peptide repertoire. Curr. Opin. Immunol. 20: 82-88 (2008). *
Blander JM. Coupling Toll-like receptor signaling with phagocytosis: potentiation of antigen presentation. Trends Immunol. 28: 19-25 (2007). *
Blander JM. Signalling and phagocytosis in the orchestration of host defence. Cell. Microbiol. 9: 290-299 (2007). *
Blander JM, Medzhitov R. Toll-dependent selection of microbial antigens for presentation by dendritic cells. Nature 440: 808-812 (2006). *
Blankenhorn EP, Cort L, Greiner DL, Guberski DL, Mordes JP. Virus-induced autoimmune diabetes in the LEW.1WR1 rat requires Iddm14 and a genetic locus proximal to the major histocompatibility complex. Diabetes 58: 2930-2938 (2009).
Blankenhorn EP, Descipio C, Rodemich L, Cort L, Leif JH, Greiner DL, Mordes JP. Refinement of the Iddm4 diabetes susceptibility locus reveals TCRVbeta4 as a candidate gene. Ann. N. Y. Acad. Sci. 1103: 128-131 (2007). *
Blankenhorn EP, Rodemich L, Martin-Fernandez C, Leif J, Greiner DL, Mordes JP. The rat diabetes susceptibility locus iddm4 and at least one additional gene are required for autoimmune diabetes induced by viral infection. Diabetes 54: 1233-1237 (2005). *
Blasko B, Banlaki Z, Gyapay G, Pozsonyi E, Sasvari-Szekely M, Rajczy K, Fust G, Szilagyi A. Linkage analysis of the C4A/C4B copy number variation and polymorphisms of the adjacent steroid 21-hydroxylase gene in a healthy population. Mol. Immunol. 46: 2623-2629 (2009). *
Bliss SK, Alcaraz A, Appleton JA. IL-10 prevents liver necrosis during murine infection with Trichinella spiralis. J. Immunol. 171: 3142-3147 (2003). *
Blomhoff A, Olsson M, Johansson S, Akselsen HE, Pociot F, Nerup J, Kockum I, Cambon-Thomsen A, Thorsby E, Undlien DE, Lie BA. Linkage disequilibrium and haplotype blocks in the MHC vary in an HLA haplotype specific manner assessed mainly by DRB1(*)03 and DRB1(*)04 haplotypes. Genes Immun. 7: 130-140 (2006). *
Bloudickova S, Rajnoch J, Lodererova A, Honsova E, Viklicky O. Mycophenolate mofetil ameliorates accelerated progressive nephropathy in rat. Kidney Blood Press. Res. 29: 60-66 (2006).
Bluestone JA. Costimulation and its role in organ transplantation. Clin. Transplant. 10: 104-109 (1996).
Bluestone JA. A balanced attack. The Scientist May, 2007 (http://www.the-scientist.com/2007/05/01/s32/1/ ) (2007).
Bluestone JA, Khattri R, Sciammas R, Sperling AI. TCR gamma delta cells: a specialized T-cell subset in the immune system. Annu. Rev. Cell. Dev. Biol. 11: 307-353 (1995). *
Blum A, Miller H. The major histocompatibility complex and inflammation. South. Med. J. 93: 169-172 (2000).
Blumberg RS, van de Wal Y, Claypool S, Corazza N, Dickinson B, Nieuwenhuis E, Pitman R, Spiekermann G, Zhu X, Colgan S, Lencer WI. The multiple roles of major histocompatibility complex class-I-like molecules in mucosal immune function. Acta Odontol. Scand. 59: 139-144 (2001).
Bochtler P, Kroger A, Schirmbeck R, Reimann J. Type I IFN-induced, NKT cell-mediated negative control of CD8 T cell priming by dendritic cells. J. Immunol. 181: 1633-1643 (2008). *
Bockermann R, Schubert D, Kamradt T, Holmdahl R. Induction of a B-cell-dependent chronic arthritis with glucose-6-phosphate isomerase. Arthritis Res. Ther. 7: R1316-R1324 (2005). *
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1996. Eur. J. Immunogenet. 24: 105-151 (1997).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1996. Hum. Immunol. 53: 98-128 (1997).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1996. Tissue Antigens 49: 297-321 (1997).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Charron D, Dupont B, Erlich HA, Fauchet R, Mach B, Mayr WR, Parham P, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1996. Vox. Sang. 73: 105-130 (1997).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1998. Eur. J. Immunogenet. 26: 81-116 (1999).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1998. Hum. Immunol. 60: 361-395 (1999).
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1998. Tissue Antigens 53: 407-446 (1999). *
Bodmer JG, Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 1998. Vox. Sang. 77: 164-191 (1999).
Bodur H, Ataman S, Akbulut L, Evcik D, Kavuncu V, Kaya T, Gunaydin R, Kuran B, Kotevoglu N, Bal A, Aydog E, Altay Z, Ugurlu H, Kocabas H, Olmez N, Yazgan P, Gursoy S, Madenci E, Ozel S, Delialioglu SU. Characteristics and medical management of patients with rheumatoid arthritis and ankylosing spondylitis. Clin. Rheumatol. 27: 1119-1125 (2008). *
Boehm T, Zufall F. MHC peptides and the sensory evaluation of genotype. Trends Neurosci. 29: 100-107 (2006). *
Boes M, Stoppelenburg AJ, Sille FC. Endosomal processing for antigen presentation mediated by CD1 and class I major histocompatibility complex: roads to display or destruction. Immunology 127: 163-170 (2009). *
Bogen B, Ruffini P. Review: to what extent are T cells tolerant to immunoglobulin variable regions? Scand. J. Immunol. 70: 526-530 (2009). *
Boin F, Wigley FM, Schneck JP, Oelke M, Rosen A. Evaluation of topoisomerase-1-specific CD8+ T-cell response in systemic sclerosis. Ann. N. Y. Acad. Sci. 1062: 137-145 (2005). *
Boitard C, Debray-Sachs M, Bach JF. Autoimmune disorders in diabetes. Adv. Nephrol. Necker Hosp. 15: 281-305 (1986).
Boldizsar F, Tarjanyi O, Nemeth P, Mikecz K, Glant TT. Th1/Th17 polarization and acquisition of an arthritogenic phenotype in arthritis-susceptible BALB/c, but not in MHC-matched, arthritis-resistant DBA/2 mice. Int. Immunol. 21: 511-522 (2009).
Bolsover WJ, Hall MA, Vaughan RW, Welsh KI, Ciclitira PJ. A family study confirms that the HLA-DP associations with celiac disease are the result of an extended HLA-DR3 haplotype. Hum. Immunol. 31: 100-108 (1991).
Bolton DL, Minang JT, Trivett MT, Song K, Tuscher JJ, Li Y, Piatak M Jr, O'Connor D, Lifson JD, Roederer M, Ohlen C. Trafficking, persistence, and activation state of adoptively transferred allogeneic and autologous simian immunodeficiency virus-specific CD8+ T cell clones during acute and chronic infection of Rhesus macaques. J. Immunol. 184: 303-314 (2010).
Bonagura VR, Cunningham-Rundles S, Edwards BL, Ilowite NT, Wedgwood JF, Valacer DJ. Common variable hypogammaglobulinemia, recurrent Pneumocystis carinii pneumonia on intravenous gamma-globulin therapy, and natural killer deficiency. Clin. Immunol. Immunopathol. 51: 216-231 (1989).
Bonamico M, Mazzilli MC, Morellini M, Vania A, Carpino F, Nicotra MR, Natali PG. Expression of class II MHC antigens in the intestinal epithelium of pediatric celiac disease. J. Pediatr. Gastroenterol. Nutr. 9: 269-275 (1989).
Bonen DK, Cho JH. The genetics of inflammatory bowel disease. Gastroenterology 124: 521-536 (2003). *
Bontrop RE. Comparative genetics of MHC polymorphisms in different primate species: duplications and deletions. Hum. Immunol. 67: 388-397 (2006).
Bontrop RE, Watkins DI. MHC polymorphism: AIDS susceptibility in non-human primates. Trends Immunol. 26: 227-233 (2005). *
Boodhoo A, Wong AM, Williamson D, Voon D, Lee S, Allcock RJ, Price P. A promoter polymorphism in the central MHC gene, IKBL, influences the binding of transcription factors USF1 and E47 on disease-associated haplotypes. Gene Expr. 12: 1-11 (2004).
Boon AC, de Mutsert G, Fouchier RA, Osterhaus AD, Rimmelzwaan GF. The hypervariable immunodominant NP418-426 epitope from the influenza A virus nucleoprotein is recognized by cytotoxic T lymphocytes with high functional avidity. J. Virol. 80: 6024-6032 (2006). *
Boots AM, Hubers H, Kouwijzer M, den Hoed-van Zandbrink L, Westrek-Esselink B, van Doorn C, Stenger R, Bos ES, van Lierop MJ, Verheijden GF, Timmers M, van Staveren C. Identification of an altered peptide ligand based on the endogenously presented, rheumatoid arthritis-associated, human cartilage glycoprotein-39 (aa263-275) epitope: an MHC anchor variant peptide for immune modulation. Arthritis Res. Ther. 9: R71 (2007). *
Borbulevych OY, Insaidoo FK, Baxter TK, Powell DJ Jr, Johnson LA, Restifo NP, Baker BM. Structures of MART-1(26/27-35) peptide/HLA-A2 complexes reveal a remarkable disconnect between antigen structural homology and T cell recognition. J. Mol. Biol. 372: 1123-1136 (2007). *
Borbulevych OY, Piepenbrink KH, Gloor BE, Scott DR, Sommese RF, Cole DK, Sewell AK, Baker BM. T cell receptor cross-reactivity directed by antigen-dependent tuning of peptide-MHC molecular flexibility. Immunity 31: 885-896 (2009). *
Bordner AJ, Mittelmann HD. Prediction of the binding affinities of peptides to class II MHC using a regularized thermodynamic model. BMC Bioinformatics 11: 41 (2010). *
Borenstein SH, Graham J, Zhang XL, Chamberlain JW. CD8+ T cells are necessary for recognition of allelic, but not locus-mismatched or xeno-, HLA class I transplantation antigens. J. Immunol. 165: 2341-2353 (2000). *
Borg NA, Wun KS, Kjer-Nielsen L, Wilce MC, Pellicci DG, Koh R, Besra GS, Bharadwaj M, Godfrey DI, McCluskey J, Rossjohn J. CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor. Nature 448: 44-49 (2007). *
Borgiani P, Vallo L, D'Apice MR, Giardina E, Pucci S, Capon F, Nistico S, Chimenti S, Pallone F, Novelli G. Exclusion of CARD15/NOD2 as a candidate susceptibility gene to psoriasis in the Italian population. Eur. J. Dermatol. 12: 540-542 (2002). *
Borrego F, Kabat J, Kim DK, Lieto L, Maasho K, Pena J, Solana R, Coligan JE. Structure and function of major histocompatibility complex (MHC) class I specific receptors expressed on human natural killer (NK) cells. Mol. Immunol. 38: 637-660 (2002). *
Bosch JJ, Iheagwara UK, Reid S, Srivastava MK, Wolf J, Lotem M, Ksander BR, Ostrand-Rosenberg S. Uveal melanoma cell-based vaccines express MHC II molecules that traffic via the endocytic and secretory pathways and activate CD8(+) cytotoxic, tumor-specific T cells. Cancer Immunol. Immunother. 59: 103-112 (2010). *
Bougacha-Elleuch N, Rebai A, Mnif M, Makni H, Bellassouad M, Jouida J, Abid M, Hammadi A. Analysis of MHC genes in a Tunisian isolate with autoimmune thyroid diseases: implication of TNF -308 gene polymorphism. J. Autoimmun. 23: 75-80 (2004).
Bougneres L, Helft J, Tiwari S, Vargas P, Chang BH, Chan L, Campisi L, Lauvau G, Hugues S, Kumar P, Kamphorst AO, Dumenil AM, Nussenzweig M, MacMicking JD, Amigorena S, Guermonprez P. A role for lipid bodies in the cross-presentation of phagocytosed antigens by MHC class I in dendritic cells. Immunity 31: 232-244 (2009). *
Boukouaci W, Busson M, Peffault de Latour R, Rocha V, Suberbielle C, Bengoufa D, Dulphy N, Haas P, Scieux C, Amroun H, Gluckman E, Krishnamoorthy R, Toubert A, Charron D, Socie G, Tamouza R. MICA-129 genotype, soluble MICA and anti-MICA antibodies as biomarkers of chronic graft versus host disease. Blood 114: 5216-5224 (2009). *
Boulanger DS, Oliveira R, Ayers L, Prior SH, James E, Williams AP, Elliott T. Absence of tapasin alters immunodominance against a lymphocytic choriomeningitis virus polytope. J. Immunol. 184: 73-83 (2010).
Boulet S, Kleyman M, Kim JY, Kamya P, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. A combined genotype of KIR3DL1 high expressing alleles and HLA-B*57 is associated with a reduced risk of HIV infection. AIDS 22: 1487-1491 (2008).
Boulet S, Sharafi S, Simic N, Bruneau J, Routy JP, Tsoukas CM, Bernard NF. Increased proportion of KIR3DS1 homozygotes in HIV-exposed uninfected individuals. AIDS 22: 595-599 (2008).
Boulter JM, Schmitz N, Sewell AK, Godkin AJ, Bachmann MF, Gallimore AM. Potent T cell agonism mediated by a very rapid TCR/pMHC interaction. Eur. J. Immunol. 37: 798-806 (2007). *
Bouma G, Crusius JB, Oudkerk Pool M, Kolkman JJ, von Blomberg BM, Kostense PJ, Giphart MJ, Schreuder GM, Meuwissen SG, Pena AS. Secretion of tumour necrosis factor alpha and lymphotoxin alpha in relation to polymorphisms in the TNF genes and HLA-DR alleles. Relevance for inflammatory bowel disease. Scand. J. Immunol. 43: 456-463 (1996).
Boutet P, Aguera-Gonzalez S, Atkinson S, Pennington CJ, Edwards DR, Murphy G, Reyburn HT, Vales-Gomez M. Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein. J. Immunol. 182: 49-53 (2009). *
Bouwman LH, Ling Z, Duinkerken G, Pipeleers DG, Roep BO. HLA incompatibility and immunogenicity of human pancreatic islet preparations cocultured with blood cells of healthy donors. Hum. Immunol. 66: 494-500 (2005).
Bovin LF, Rieneck K, Workman C, Nielsen H, Sorensen SF, Skjodt H, Florescu A, Brunak S, Bendtzen K. Blood cell gene expression profiling in rheumatoid arthritis. Discriminative genes and effect of rheumatoid factor. Immunol. Lett. 93: 217-226 (2004).
Bowcock AM. The genetics of psoriasis and autoimmunity. Annu. Rev. Genomics Hum. Genet. 6: 93-122 (2005). *
Bowcock AM, Barker JN. Genetics of psoriasis: the potential impact on new therapies. J. Am. Acad. Dermatol. 49: S51-S56 (2003).
Bowlus CL. The role of iron in T cell development and autoimmunity. Autoimmun. Rev. 2: 73-78 (2003).
Bowlus CL. Chapter 11. Tumor immunology: hepatocellular carcinoma, cholangiocarcinoma, and metastatic neoplasms. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 137-149 (2007). *
Bowness P. HLA B27 in health and disease: a double-edged sword? Rheumatology (Oxford) 41: 857-868 (2002). *
Bowness P, Zaccai N, Bird L, Jones EY. HLA-B27 and disease pathogenesis: new structural and functional insights. Expert Rev. Mol. Med. 1: 1-10 (1999). *
Boyington JC, Motyka SA, Schuck P, Brooks AG, Sun PD. Crystal structure of an NK cell immunoglobulin-like receptor in complex with its class I MHC ligand. Nature 405: 537-543 (2000). *
Boyington JC, Sun PD. A structural perspective on MHC class I recognition by killer cell immunoglobulin-like receptors. Mol. Immunol. 38: 1007-1021 (2002). *
Boykinova OB, Stoilova YD, Tsvetkova TZ, Baltadjiev IG. Epidemiological, immunological and clinical characteristics of acute hepatitis C. Folia Med. (Plovdiv.) 51: 61-69 (2009).
Boyle LH, Gillingham AK, Munro S, Trowsdale J. Selective export of HLA-F by its cytoplasmic tail. J. Immunol. 176: 6464-6472 (2006). *
Boyman O, Cho JH, Tan JT, Surh CD, Sprent J. A major histocompatibility complex class I-dependent subset of memory phenotype CD8+ cells. J. Exp. Med. 203: 1817-1825 (2006). *
Braaten DC, McClellan JS, Messaoudi I, Tibbetts SA, McClellan KB, Nikolich-Zugich J, Virgin HW. Effective control of chronic gamma-herpesvirus infection by unconventional MHC class Ia-independent CD8 T cells. PLoS Pathog. 2: e37 (2006). *
Bradstock KF, Hertzberg MS, Kerridge IH, Svennilson J, McGurgan M, Huang G, Antonenas V, Gottlieb DJ. Unrelated umbilical cord blood transplantation for adults with haematological malignancies: results from a single Australian centre. Intern. Med. J. 36: 355-361 (2006). *
Braegger CP, MacDonald TT. Immune mechanisms in chronic inflammatory bowel disease. Ann. Allergy 72: 135-141 (1994).
Brand DD, Kang AH, Rosloniec EF. The mouse model of collagen-induced arthritis. Methods Mol. Med. 102: 295-312 (2004).
Brand DD, Kang AH, Rosloniec EF. Immunopathogenesis of collagen arthritis. Springer Semin. Immunopathol. 25: 3-18 (2003). *
Brandmaier AG, Leitner WW, Ha SP, Sidney J, Restifo NP, Touloukian CE. High-avidity autoreactive CD4+ T cells induce host CTL, overcome Tregs and mediate tumor destruction. J. Immunother. 32: 677-688 (2009).
Brandtzaeg P, Johansen FE. Mucosal B cells: phenotypic characteristics, transcriptional regulation, and homing properties. Immunol. Rev. 206: 32-63 (2005). *
Brant SR, Shugart YY. Inflammatory bowel disease gene hunting by linkage analysis - rationale, methodology, and present status of the field. Inflamm. Bowel Dis. 10: 300-311 (2004). *
Braun J. Therapy of spondyloarthritides. Adv. Exp. Med. Biol. 649: 133-147 (2009).
Bravo MJ, Colmenero JD, Martin J, Alonso A, Caballero A. Polymorphism of the transmembrane region of the MICA gene and human brucellosis. Tissue Antigens 69: 358-360 (2007). *
Bray PF, Luka J, Bray PF, Culp KW, Schlight JP. Antibodies against Epstein-Barr nuclear antigen (EBNA) in multiple sclerosis CSF, and two pentapeptide sequence identities between EBNA and myelin basic protein. Neurology 42: 1798-1804 (1992).
Breban M, Miceli-Richard C, Zinovieva E, Monnet D, Said-Nahal R. The genetics of spondyloarthropathies. Joint Bone Spine 73: 355-362 (2006). *
Bregenholt S, Brimnes J, Nissen MH, Claesson MH. In vitro activated CD4+ T cells from interferon-gamma (IFN-gamma)-deficient mice induce intestinal inflammation in immunodeficient hosts. Clin. Exp. Immunol. 118: 228-234 (1999). *
Brenchley JM, Douek DC, Ambrozak DR, Chatterji M, Betts MR, Davis LS, Koup RA. Expansion of activated human naive T-cells precedes effector function. Clin. Exp. Immunol. 130: 432-440 (2002). *
Brennan PA, Kendrick KM. Mammalian social odours: attraction and individual recognition. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 361: 2061-2078 (2006). *
Brenner CD, King S, Przewoznik M, Wolters I, Adam C, Bornkamm GW, Busch DH, Rocken M, Mocikat R. Requirements for control of B-cell lymphoma by natural killer cells. Eur. J. Immunol. Nov 30 [Epub ahead of print] (2009). *
Brenner M, Laragione T, Yarlett NC, Gulko PS. Genetic regulation of T regulatory, CD4, and CD8 cell numbers by the arthritis severity loci Cia5a, Cia5d, and the MHC/Cia1 in the rat. Mol. Med. 13: 277-287 (2007). *
Brenner M, Laragione T, Yarlett NC, Li W, Mello A, Gulko PS. Cia27 is a novel non-MHC arthritis severity locus on rat chromosome 10 syntenic to the rheumatoid arthritis 17q22-q25 locus. Genes Immun. 7: 335-341 (2006). *
Brenner M, Meng HC, Yarlett NC, Griffiths MM, Remmers EF, Wilder RL, Gulko PS. The non-major histocompatibility complex quantitative trait locus Cia10 contains a major arthritis gene and regulates disease severity, pannus formation, and joint damage. Arthritis Rheum. 52: 322-332 (2005). *
Breous E, Somanathan S, Vandenberghe LH, Wilson JM. Hepatic regulatory T cells and Kupffer cells are crucial mediators of systemic T cell tolerance to antigens targeting murine liver. Hepatology 50: 612-621 (2009). *
Breslow RG, Rao JJ, Xing W, Hong DI, Barrett NA, Katz HR. Inhibition of Th2 adaptive immune responses and pulmonary inflammation by leukocyte Ig-like receptor B4 on dendritic cells. J. Immunol. 184: 1003-1013 (2010).
Brett PM, Yiannakou JY, Morris MA, Bronson SR, Mathew C, Curtis D, Ciclitira PJ. A pedigree-based linkage study of coeliac disease: failure to replicate previous positive findings. Ann. Hum. Genet. 62: 25-32 (1998). *
Breur-Vriesendorp BS, Ivanyi P. Self-restricted primary human histocompatibility leukocyte antigen (HLA)-specific cytotoxic T lymphocytes. Int. Immunol. 5: 103-107 (1993).
Brickner AG. Mechanisms of minor histocompatibility antigen immunogenicity: the role of infinitesimal versus structurally profound polymorphisms. Immunol. Res. 36: 33-42 (2006). *
Briggs D, Stephens C, Vaughan R, Welsh K, Black C. A molecular and serologic analysis of the major histocompatibility complex and complement component C4 in systemic sclerosis. Arthritis Rheum. 36: 943-954 (1993).
Briggs DC, Donaldson PT, Hayes P, Welsh KI, Williams R, Neuberger JM. A major histocompatibility complex class III allotype (C4B 2) associated with primary biliary cirrhosis (PBC). Tissue Antigens 29: 141-145 (1987).
Briggs L, Laird K, Boss JM, Garvie CW. Formation of the RFX gene regulatory complex induces folding of the interaction domain of RFXAP. Proteins 76: 655-664 (2009). *
Brigl M, Brenner MB. CD1: antigen presentation and T cell function. Annu. Rev. Immunol. 22: 817-890 (2004). *
Brignone C, Grygar C, Marcu M, Schakel K, Triebel F. A soluble form of lymphocyte activation gene-3 (IMP321) induces activation of a large range of human effector cytotoxic cells. J. Immunol. 179: 4202-4211 (2007). *
Brilot F, Geenen V. Role of viral infections in the pathogenesis of type 1 diabetes. Rev. Med. Liege. 60: 297-302 (2005).
Brims DR, Qian J, Jarchum I, Mikesh L, Palmieri E, Ramagopal UA, Malashkevich VN, Chaparro RJ, Lund T, Hattori M, Shabanowitz J, Hunt DF, Nathenson SG, Almo SC, Dilorenzo TP. Predominant occupation of the class I MHC molecule H-2Kwm7 with a single self-peptide suggests a mechanism for its diabetes-protective effect. Int. Immunol. Jan 21 [Epub ahead of print] (2010).
Brintnell W, Bell DA, Hill JA, Jevnikar AM, Sette A, Sidney J, Doege K, Cairns E. The influence of MHC class II molecules containing the rheumatoid arthritis shared epitope on the immune response to aggrecan G1 and its peptides. Scand. J. Immunol. 65: 444-452 (2007). *
Brodin P, Karre K, Hoglund P. NK cell education: not an on-off switch but a tunable rheostat. Trends Immunol. 30: 143-149 (2009). *
Brogan PA, Shah V, Klein N, Dillon MJ. Vbeta-restricted T cell adherence to endothelial cells: a mechanism for superantigen-dependent vascular injury. Arthritis Rheum. 50: 589-597 (2004). *
Broides A, Shubinsky G, Parvari R, Grimbacher B, Somech R, Garty BZ, Levy J. MHC class 2 deficiency and X-linked agammaglobulinaemia in a consanguineous extended family. Int. J. Immunogenet. 36: 223-226 (2009). *
Bronson PG, Criswell LA, Barcellos LF. The MHC2TA -168A/G polymorphism and risk for rheumatoid arthritis: a meta-analysis of 6,861 patients and 9,270 controls reveals no evidence for association. Ann. Rheum. Dis. 67: 933-936 (2008).
Bronson PG, Ramsay PP, Thomson G, Barcellos LF; Diabetes Genetics Consortium. Analysis of maternal-offspring HLA compatibility, parent-of-origin and non-inherited maternal effects for the classical HLA loci in type 1 diabetes. Diabetes Obes. Metab. 11 Suppl. 1: 74-83 (2009). *
Brooimans RA, Boyce CS, Popma J, Broyles DA, Gratama JW, Southwick PC, Keeney M. Analytical performance of a standardized single-platform MHC tetramer assay for the identification and enumeration of CMV-specific CD8+ T lymphocytes. Cytometry A. 73A: 992-1000 (2008).
Broome U, Glaumann H, Hultcrantz R, Forsum U. Distribution of HLA-DR, HLA-DP, HLA-DQ antigens in liver tissue from patients with primary sclerosing cholangitis. Scand. J. Gastroenterol. 25: 54-58 (1990).
Broome U, Hultcrantz R, Scheynius A. Lack of concomitant expression of ICAM-1 and HLA-DR on bile duct cells from patients with primary sclerosing cholangitis and primary biliary cirrhosis. Scand. J. Gastroenterol. 28: 126-130 (1993).
Brorsson C, Hansen NT, Lage K, Bergholdt R, Brunak S, Pociot F; Diabetes Genetics Consortium. Identification of T1D susceptibility genes within the MHC region by combining protein interaction networks and SNP genotyping data. Diabetes Obes. Metab. 11 Suppl. 1: 60-66 (2009). *
Brown GR, Lee EL, Thiele DL. TNF enhances CD4+ T cell alloproliferation, IFN-gamma responses, and intestinal graft-versus-host disease by IL-12-independent mechanisms. J. Immunol. 170: 5082-5088 (2003). *
Brown JJ, Ollier WE, Thomson W, Bayat A. Positive association of HLA-DRB1*15 with keloid disease in Caucasians. Int. J. Immunogenet. 35: 303-307 (2008). *
Brown MA. Genetics of ankylosing spondylitis. Curr. Opin. Rheumatol. Jan 15 [Epub ahead of print] (2010).
Brown MA. Genetics and the pathogenesis of ankylosing spondylitis. Curr. Opin. Rheumatol. 21: 318-323 (2009).
Brown MA, Brophy S, Bradbury L, Hamersma J, Timms A, Laval S, Cardon L, Calin A, Wordsworth BP. Identification of major loci controlling clinical manifestations of ankylosing spondylitis. Arthritis Rheum. 48: 2234-2239 (2003). *
Brown MA, Pile KD, Kennedy LG, Campbell D, Andrew L, March R, Shatford JL, Weeks DE, Calin A, Wordsworth BP. A genome-wide screen for susceptibility loci in ankylosing spondylitis. Arthritis Rheum. 41: 588-595 (1998). *
Brown NK, McCormick DJ, David CS, Kong YC. H2E-derived Ealpha52-68 peptide presented by H2Ab interferes with clonal deletion of autoreactive T cells in autoimmune thyroiditis. J. Immunol. 180: 7039-7046 (2008). *
Brown WM, Pierce J, Hilner JE, Perdue LH, Lohman K, Li L, Venkatesh RB, Hunt S, Mychaleckyj JC, Deloukas P; Diabetes Genetics Consortium. Overview of the MHC fine mapping data. Diabetes Obes. Metab. 11 Suppl. 1: 2-7 (2009). *
Brucet M, Marques L, Sebastian C, Lloberas J, Celada A. Regulation of murine Tap1 and Lmp2 genes in macrophages by interferon gamma is mediated by STAT1 and IRF-1. Genes Immun. 5: 26-35 (2004). *
Brumeanu TD, Bona CA, Casares S. T-cell tolerance and autoimmune diabetes. Int. Rev. Immunol. 20: 301-331 (2001).
Brunhuber T, Haybaeck J, Schafer G, Mikuz G, Langhoff E, Saeland S, Lebecque S, Romani N, Obrist P. Immunohistochemical tracking of an immune response in mammary Paget's disease. Cancer Lett. 272: 206-220 (2008).
Brunner T, Arnold D, Wasem C, Laissue JA, Mueller C. Death receptor-mediated suicide: a novel target of autoimmune disease treatment. Expert Opin. Investig. Drugs 8: 1359-1372 (1999).
Brutkiewicz RR. CD1d ligands: the good, the bad, and the ugly. J. Immunol. 177: 769-775 (2006). *
Bryceson YT, March ME, Ljunggren HG, Long EO. Activation, coactivation, and costimulation of resting human natural killer cells. Immunol. Rev. 214: 73-91 (2006). *
Buchli R, Vangundy RS, Giberson CF, Hildebrand WH. Critical factors in the development of fluorescence polarization-based peptide binding assays: an equilibrium study monitoring specific peptide binding to soluble HLA-A*0201. J. Immunol. Methods 314: 38-53 (2006). *
Bucin D, Truedsson L, Hammarstrom L, Smith CI, Sjoholm AG. C4 polymorphism and major histocompatibility complex haplotypes in IgA deficiency: association with C4A null haplotypes. Exp. Clin. Immunogenet. 8: 233-241 (1991).
Bueno C, Criado G, McCormick JK, Madrenas J. T cell signalling induced by bacterial superantigens. Chem. Immunol. Allergy 93: 161-180 (2007).
Buhler OT, Wiedig CA, Schmid Y, Grassl GA, Bohn E, Autenrieth IB. The Yersinia enterocolitica invasin protein promotes major histocompatibility complex class I- and class II-restricted T-cell responses. Infect. Immun. 74: 4322-4329 (2006). *
Bui HH, Schiewe AJ, von Grafenstein H, Haworth IS. Structural prediction of peptides binding to MHC class I molecules. Proteins 63: 43-52 (2006). *
Bui HH, Sidney J, Dinh K, Southwood S, Newman MJ, Sette A. Predicting population coverage of T-cell epitope-based diagnostics and vaccines. BMC Bioinformatics 7: 153 (2006). *
Bukreyev A, Serra ME, Laham FR, Melendi GA, Kleeberger SR, Collins PL, Polack FP. The cysteine-rich region and secreted form of the attachment G glycoprotein of respiratory syncytial virus enhance the cytotoxic T-lymphocyte response despite lacking major histocompatibility complex class I-restricted epitopes. J. Virol. 80: 5854-5861 (2006). *
Buning J, Hundorfean G, Schmitz M, Zimmer KP, Strobel S, Gebert A, Ludwig D. Antigen targeting to MHC class II-enriched late endosomes in colonic epithelial cells: trafficking of luminal antigens studied in vivo in Crohn's colitis patients. FASEB J. 20: 359-361 (2006). *
Buning J, von Smolinski D, Tafazzoli K, Zimmer KP, Strobel S, Apostolaki M, Kollias G, Heath JK, Ludwig D, Gebert A. Multivesicular bodies in intestinal epithelial cells: responsible for MHC class II-restricted antigen processing and origin of exosomes. Immunology 125: 510-521 (2008). *
Burastero SE, Rossi GA, Crimi E. Selective differences in the expression of the homing receptors of helper lymphocyte subsets. Clin. Immunol. Immunopathol. 89: 110-116 (1998). *
Burchill MA, Yang J, Vang KB, Moon JJ, Chu HH, Lio CW, Vegoe AL, Hsieh CS, Jenkins MK, Farrar MA. Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. Immunity 28: 112-121 (2008). *
Burgdorf S, Kurts C. Endocytosis mechanisms and the cell biology of antigen presentation. Curr. Opin. Immunol. 20: 89-95 (2008). *
Burgos JS, Serrano-Saiz E, Sastre I, Valdivieso F. ICP47 mediates viral neuroinvasiveness by induction of TAP protein following intravenous inoculation of herpes simplex virus type 1 in mice. J. Neurovirol. 12: 420-427 (2006).
Burlet-Schiltz O, Claverol S, Gairin JE, Monsarrat B. The use of mass spectrometry to identify antigens from proteasome processing. Methods Enzymol. 405: 264-300 (2005).
Burroughs NJ, van der Merwe PA. Stochasticity and spatial heterogeneity in T-cell activation. Immunol. Rev. 216: 69-80 (2007). *
Burrows GG. Systemic immunomodulation of autoimmune disease using MHC-derived recombinant TCR ligands. Curr. Drug Targets Inflamm. Allergy 4: 185-193 (2005).
Burrows JM, Bell MJ, Brennan R, Miles JJ, Khanna R, Burrows SR. Preferential binding of unusually long peptides to MHC class I and its influence on the selection of target peptides for T cell recognition. Mol. Immunol. 45: 1818-1824 (2008). *
Burrows SR, Rossjohn J, McCluskey J. Have we cut ourselves too short in mapping CTL epitopes? Trends Immunol. 27: 11-16 (2006). *
Burster T, Marin-Esteban V, Boehm BO, Dunn S, Rotzschke O, Falk K, Weber E, Verhelst SH, Kalbacher H, Driessen C. Design of protease-resistant myelin basic protein-derived peptides by cleavage site directed amino acid substitutions. Biochem. Pharmacol. 74: 1514-1523 (2007). *
Burt BM, Plitas G, Zhao Z, Bamboat ZM, Nguyen HM, Dupont B, Dematteo RP. The lytic potential of human liver NK cells is restricted by their limited expression of inhibitory killer Ig-like receptors. J. Immunol. 183: 1789-1796 (2009).
Busch R, Rinderknecht CH, Roh S, Lee AW, Harding JJ, Burster T, Hornell TM, Mellins ED. Achieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expression. Immunol. Rev. 207: 242-260 (2005). *
Busche A, Goldmann T, Naumann U, Steinle A, Brandau S. Natural killer cell-mediated rejection of experimental human lung cancer by genetic overexpression of major histocompatibility complex class I chain-related gene A. Hum. Gene Ther. 17: 135-146 (2006).
Butler JE, Moore MB, Presnell SR, Chan HW, Chalupny NJ, Lutz CT. Proteasome regulation of ULBP1 transcription. J. Immunol. 182: 6600-6609 (2009).
Butler M, Ng CY, van Heel DA, Lombardi G, Lechler R, Playford RJ, Ghosh S. Modulation of dendritic cell phenotype and function in an in vitro model of the intestinal epithelium. Eur. J. Immunol. 36: 864-874 (2006). *
Butovsky O, Landa G, Kunis G, Ziv Y, Avidan H, Greenberg N, Schwartz A, Smirnov I, Pollack A, Jung S, Schwartz M. Induction and blockage of oligodendrogenesis by differently activated microglia in an animal model of multiple sclerosis. J. Clin. Invest. 116: 905-915 (2006). *
Butts CL, Bowers E, Horn JC, Shukair SA, Belyavskaya E, Tonelli L, Sternberg EM. Inhibitory effects of progesterone differ in dendritic cells from female and male rodents. Gend. Med. 5: 434-447 (2008).
Caforio AL, Iliceto S. Genetically determined myocarditis: clinical presentation and immunological characteristics. Curr. Opin. Cardiol. 23: 219-226 (2008).
Caforio AL, Vinci A, Iliceto S. Anti-heart autoantibodies in familial dilated cardiomyopathy. Autoimmunity 41: 462-469 (2008).
Cagliani R, Fumagalli M, Riva S, Pozzoli U, Comi GP, Menozzi G, Bresolin N, Sironi M. The signature of long-standing balancing selection at the human defensin beta-1 promoter. Genome Biol. 9: R143 (2008). *
Cai G, Zhang J, Liu L, Shen Q. Successful treatment of experimental autoimmune myocarditis by adenovirus-mediated gene transfer of antisense CIITA. J. Mol. Cell. Cardiol. 38: 593-605 (2005). *
Caillat-Zucman S, Gimenez JJ, Wambergue F, Albouze G, Lebkiri B, Naret C, Moynot A, Jungers P, Bach JF. Distinct HLA class II alleles determine antibody response to vaccination with hepatitis B surface antigen. Kidney Int. 53: 1626-1630 (1998). *
Caillier SJ, Briggs F, Cree BA, Baranzini SE, Fernandez-Vina M, Ramsay PP, Khan O, Royal W 3rd, Hauser SL, Barcellos LF, Oksenberg JR. Uncoupling the roles of HLA-DRB1 and HLA-DRB5 genes in multiple sclerosis. J. Immunol. 181: 5473-5480 (2008). *
Calbo S, Delagreverie H, Arnoult C, Authier FJ, Tron F, Boyer O. Functional tolerance of CD8+ T cells induced by muscle-specific antigen expression. J. Immunol. 181: 408-417 (2008). *
Calderon B, Suri A, Miller MJ, Unanue ER. Dendritic cells in islets of Langerhans constitutively present beta cell-derived peptides bound to their class II MHC molecules. Proc. Natl. Acad. Sci. U.S.A. 105: 6121-6126 (2008). *
Callaghan CJ, Rouhani FJ, Negus MC, Curry AJ, Bolton EM, Bradley JA, Pettigrew GJ. Abrogation of antibody-mediated allograft rejection by regulatory CD4 T cells with indirect allospecificity. J. Immunol. 178: 2221-2228 (2007). *
Callahan MK, Garg M, Srivastava PK. Heat-shock protein 90 associates with N-terminal extended peptides and is required for direct and indirect antigen presentation. Proc. Natl. Acad. Sci. U.S.A. 105: 1662-1667 (2008). *
Callard RE. Decision-making by the immune response. Immunol. Cell Biol. 85: 300-305 (2007). *
Calmus Y, Arvieux C, Gane P, Boucher E, Nordlinger B, Rouger P, Poupon R. Cholestasis induces major histocompatibility complex class I expression in hepatocytes. Gastroenterology 102: 1371-1377 (1992).
Calmus Y, Gane P, Rouger P, Poupon R. Hepatic expression of class I and class II major histocompatibility complex molecules in primary biliary cirrhosis: effect of ursodeoxycholic acid. Hepatology 11: 12-15 (1990).
Calmus Y, Poupon R. Ursodeoxycholic acid (UDCA) in the treatment of chronic cholestatic diseases. Biochimie 73: 1335-1338 (1991).
Calvo B, Castano L, Marcus-Bagley D, Fici DA, Awdeh Z, Alper CA. The [HLA-B18, F1C30, DR3] conserved extended haplotype carries a susceptibility gene for IgD deficiency. J. Clin. Immunol. 20: 216-220 (2000). *
Camarena A, Juarez A, Mejia M, Estrada A, Carrillo G, Falfan R, Zuniga J, Navarro C, Granados J, Selman M. Major histocompatibility complex and tumor necrosis factor-alpha polymorphisms in pigeon breeder's disease. Am. J. Respir. Crit. Care Med. 163: 1528-1533 (2001). *
Cambon-Thomsen A, Roth MP. Genetics of autoimmune diseases. Rev. Prat. 44: 43-52 (1994).
Cambra A, Munoz-Saa I, Cresp� C, Serra A, Etxagibel A, Matamoros N, Mila J, Julia MR. MICA-HLA-B haplotype diversity and linkage disequilibrium in a population of Jewish descent from Majorca (Balearic Islands). Hum. Immunol. 70: 513-517 (2009).
Camelo S, Lajavardi L, Bochot A, Goldenberg B, Naud MC, Brunel N, Lescure B, Klein C, Fattal E, Behar-Cohen F, de Kozak Y. Protective effect of intravitreal injection of vasoactive intestinal peptide (VIP)-loaded liposomes on experimental autoimmune uveoretinitis. J. Ocul. Pharmacol. Ther. 25: 9-21 (2009).
Cameron FH, Russell PJ, Sullivan J, Geczy AF. Is a Klebsiella plasmid involved in the aetiology of ankylosing spondylitis in HLA-B27-positive individuals? Mol. Immunol. 20: 563-566 (1983).
Cameron PU, Mallal SA, French MA, Dawkins RL. Major histocompatibility complex genes influence the outcome of HIV infection. Ancestral haplotypes with C4 null alleles explain diverse HLA associations. Hum. Immunol. 29: 282-295 (1990).
Campbell KS, Colonna M. Human natural killer cell receptors and signal transduction. Int. Rev. Immunol. 20: 333-370 (2001).
Campbell PD, Estella E, Dudek NL, Jhala G, Thomas HE, Kay TW, Mannering SI. Cytotoxic T-lymphocyte-mediated killing of human pancreatic islet cells in vitro. Hum. Immunol. 69: 543-551 (2008).
Candore G, Balistreri CR, Colonna-Romano G, Lio D, Caruso C. Major histocompatibility complex and sporadic Alzheimer's disease: a critical reappraisal. Exp. Gerontol. 39: 645-652 (2004). *
Cao MY, Thonnard J, Deggouj N, Gersdorff M, Philippe M, Osselaer JC, Tomasi JP. HLA class II-associated genetic susceptibility in idiopathic progressive sensorineural hearing loss. Ann. Otol. Rhinol. Laryngol. 105: 628-633 (1996).
Cao TM, Lazzeroni LC, Tsai S, Pang WW, Kao A, Camp NJ, Thomas A, Shizuru JA. Identification of a major susceptibility locus for lethal graft-versus-host disease in MHC-matched mice. J. Immunol. 183: 462-469 (2009).
Capasso M, Di Muzio A, Comar M, Robuffo I, Gambi A, Crovella S, Pizzigallo E, Campello C, Uncini A. The association of chronic hepatitis B and myopathy. Neurology 67: 1467-1469 (2006).
Capon F, Bijlmakers MJ, Wolf N, Quaranta M, Huffmeier U, Allen M, Timms K, Abkevich V, Gutin A, Smith R, Warren RB, Young HS, Worthington J, Burden AD, Griffiths CE, Hayday A, Nestle FO, Reis A, Lanchbury J, Barker JN, Trembath RC. Identification of ZNF313/RNF114 as a novel psoriasis susceptibility gene. Hum. Mol. Genet. 17: 1938-1945 (2008). *
Capon F, Di Meglio P, Szaub J, Prescott NJ, Dunster C, Baumber L, Timms K, Gutin A, Abkevic V, Burden AD, Lanchbury J, Barker JN, Trembath RC, Nestle FO. Sequence variants in the genes for the interleukin-23 receptor (IL23R) and its ligand (IL12B) confer protection against psoriasis. Hum. Genet. 122: 201-206 (2007). *
Capon F, Munro M, Barker J, Trembath R. Searching for the major histocompatibility complex psoriasis susceptibility gene. J. Invest. Dermatol. 118: 745-751 (2002). *
Capon F, Trembath RC, Barker JN. An update on the genetics of psoriasis. Dermatol. Clin. 22: 339-347, vii (2004).
Caporale CM, Papola F, Fioroni MA, Aureli A, Giovannini A, Notturno F, Adorno D, Caporale V, Uncini A. Susceptibility to Guillain-Barre syndrome is associated to polymorphisms of CD1 genes. J. Neuroimmunol. 177: 112-118 (2006).
Carbone E, Neri P, Mesuraca M, Fulciniti MT, Otsuki T, Pende D, Groh V, Spies T, Pollio G, Cosman D, Catalano L, Tassone P, Rotoli B, Venuta S. HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood 105: 251-258 (2005). *
Cardell SL. The natural killer T lymphocyte: a player in the complex regulation of autoimmune diabetes in non-obese diabetic mice. Clin. Exp. Immunol. 143: 194-202 (2006). *
Cardoso CB, Uthida-Tanaka AM, Magalhaes RF, Magna LA, Kraemer MH. Association between psoriasis vulgaris and MHC-DRB, -DQB genes as a contribution to disease diagnosis. Eur. J. Dermatol. 15: 159-163 (2005).
Cariappa A, Sands B, Forcione D, Finkelstein D, Podolsky DK, Pillai S. Analysis of MHC class II DP, DQ and DR alleles in Crohn's disease. Gut 43: 210-215 (1998). *
Carl PL, Temple BR, Cohen PL. Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity. Arthritis Res. Ther. 7: R1360-R1374 (2005). *
Carlen L, Sakuraba K, Stahle M, Sanchez F. HLA-C expression pattern is spatially different between psoriasis and eczema skin lesions. J. Invest. Dermatol. 127: 342-348 (2007). *
Carlsen S, Lu S, Holmdahl R. Arthritis induced with minor cartilage proteins. Methods Mol. Med. 136: 225-242 (2007).
Carosella ED, Favier B, Rouas-Freiss N, Moreau P, Lemaoult J. Beyond the increasing complexity of the immunomodulatory HLA-G molecule. Blood 111: 4862-4870 (2008). *
Carpentier PA, Getts MT, Miller SD. Pro-inflammatory functions of astrocytes correlate with viral clearance and strain-dependent protection from TMEV-induced demyelinating disease. Virology 375: 24-36 (2008). *
Carr WH, Pando MJ, Parham P. KIR3DL1 polymorphisms that affect NK cell inhibition by HLA-Bw4 ligand. J. Immunol. 175: 5222-5229 (2005). *
Carralot JP, Lemmel C, Stevanovic S, Pascolo S. Mass spectrometric identification of an HLA-A*0201 epitope from Plasmodium falciparum MSP-1. Int. Immunol. 20: 1451-1456 (2008).
Carreno LJ, Bueno SM, Bull P, Nathenson SG, Kalergis AM. The half-life of the T-cell receptor/peptide-major histocompatibility complex interaction can modulate T-cell activation in response to bacterial challenge. Immunology 121: 227-237 (2007). *
Carrington M, Nelson GW, Martin MP, Kissner T, Vlahov D, Goedert JJ, Kaslow R, Buchbinder S, Hoots K, O'Brien SJ. HLA and HIV-1: heterozygote advantage and B*35-Cw*04 disadvantage. Science 283: 1748-1752 (1999). *
Carroll JM, Crompton T, Seery JP, Watt FM. Transgenic mice expressing IFN-gamma in the epidermis have eczema, hair hypopigmentation, and hair loss. J. Invest. Dermatol. 108: 412-422 (1997).
Caruso R, Sarra M, Stolfi C, Rizzo A, Fina D, Fantini MC, Pallone F, Macdonald TT, Monteleone G. Interleukin-25 inhibits interleukin-12 production and Th1 cell-driven inflammation in the gut. Gastroenterology 136: 2270-2279 (2009). *
Casartelli N, Giolo G, Neri F, Haller C, Potesta M, Rossi P, Fackler OT, Doria M. The Pro78 residue regulates the capacity of the human immunodeficiency virus type 1 Nef protein to inhibit recycling of major histocompatibility complex class I molecules in an SH3-independent manner. J. Gen. Virol. 87: 2291-2296 (2006). *
Casp CB, She JX, McCormack WT. Genes of the LMP/TAP cluster are associated with the human autoimmune disease vitiligo. Genes Immun. 4: 492-499 (2003). *
Castell JV, Castell M. Allergic hepatitis induced by drugs. Curr. Opin. Allergy Clin. Immunol. 6: 258-265 (2006).
Caturegli P, Kimura H, Rocchi R, Rose NR. Autoimmune thyroid diseases. Curr. Opin. Rheumatol. 19: 44-48 (2007).
Cavanaugh JA, Pavli P. Ulcerative colitis: a genetic disease? Baillieres Clin. Gastroenterol. 11: 1-15 (1997).
Cavestro GM, Frulloni L, Neri TM, Seghini P, Nouvenne A, Zanetti A, Bovo P, Di Mario F, Okolicsanyi L, Cavallini G. Association of HLA-DRB1*0401 allele with chronic pancreatitis. Pancreas 26: 388-391 (2003).
Cayabyab MJ, Hovav AH, Hsu T, Krivulka GR, Lifton MA, Gorgone DA, Fennelly GJ, Haynes BF, Jacobs WR Jr, Letvin NL. Generation of CD8+ T-cell responses by a recombinant nonpathogenic Mycobacterium smegmatis vaccine vector expressing human immunodeficiency virus type 1 Env. J. Virol. 80: 1645-1652 (2006). *
Cecconi V, Moro M, Mare SD, Dellabona P, Casorati G. Use of MHC class II tetramers to investigate CD4(+) T cell responses: problems and solutions. Cytometry A. 73A: 1010-1018 (2008).
Cecere A, Caiazzo R, Romano C, Gattoni A. Primary biliary cirrhosis. Clin. Ter. 149: 143-150 (1998).
Cecere A, Tancredi L, Gattoni A. Primary sclerosing cholangitis. Panminerva Med. 44: 313-323 (2002).
Cerna M, Kolostova K, Novota P, Romzova M, Cejkova P, Pinterova D, Pruhova S, Treslova L, Andel M. Autoimmune diabetes mellitus with adult onset and type 1 diabetes mellitus in children have different genetic predispositions. Ann. N. Y. Acad. Sci. 1110: 140-150 (2007). *
Cernadas M, Cavallari M, Watts G, Mori L, De Libero G, Brenner MB. Early recycling compartment trafficking of CD1a is essential for its intersection and presentation of lipid antigens. J. Immunol. Dec 21 [Epub ahead of print] (2009).
Cernea S, Herold KC. Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies. Clin. Immunol. Oct 15 [Epub ahead of print] (2009). *
Cerruti F, Martano M, Petterino C, Bollo E, Morello E, Bruno R, Buracco P, Cascio P. Enhanced expression of interferon-gamma-induced antigen-processing machinery components in a spontaneously occurring cancer. Neoplasia 9: 960-969 (2007). *
Cerwenka A, Bakker AB, McClanahan T, Wagner J, Wu J, Phillips JH, Lanier LL. Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 12: 721-727 (2000). *
Cerwenka A, Lanier LL. NKG2D ligands: unconventional MHC class I-like molecules exploited by viruses and cancer. Tissue Antigens 61: 335-343 (2003). *
Cerwenka A, Lanier LL. Natural killer cells, viruses and cancer. Nat. Rev. Immunol. 1: 41-49 (2001). *
Chaise C, Buchan SL, Rice J, Marquet J, Rouard H, Kuentz M, Vittes GE, Molinier-Frenkel V, Farcet JP, Stauss HJ, Delfau-Larue MH, Stevenson FK. DNA vaccination induces WT1-specific T-cell responses with potential clinical relevance. Blood 112: 2956-2964 (2008). *
Chaitra MG, Shaila MS, Nayak R. Evaluation of T-cell responses to peptides with MHC class I-binding motifs derived from PE_PGRS 33 protein of Mycobacterium tuberculosis. J. Med. Microbiol. 56: 466-474 (2007). *
Chaix R, Cao C, Donnelly P. Is mate choice in humans MHC-dependent? PLoS Genet. 4: e1000184 (2008). *
Chalermsarp N, Azuma M. Identification of three distinct subsets of migrating dendritic cells from oral mucosa within the regional lymph nodes. Immunology 127: 558-566 (2009). *
Chalifour A, Scarpellino L, Back J, Brodin P, Devevre E, Gros F, Levy F, Leclercq G, Hoglund P, Beermann F, Held W. A role for cis interaction between the inhibitory Ly49A receptor and MHC class I for natural killer cell education. Immunity 30: 337-347 (2009). *
Chamuleau ME, Westers TM, van Dreunen L, Groenland J, Zevenbergen A, Eeltink CM, Ossenkoppele GJ, van de Loosdrecht AA. Immune mediated autologous cytotoxicity against hematopoietic precursor cells in patients with myelodysplastic syndrome. Haematologica 94: 496-506 (2009). *
Chan CW, Crafton E, Fan HN, Flook J, Yoshimura K, Skarica M, Brockstedt D, Dubensky TW, Stins MF, Lanier LL, Pardoll DM, Housseau F. Interferon-producing killer dendritic cells provide a link between innate and adaptive immunity. Nat. Med. 12: 207-213 (2006). *
Chan J, Clements W, Field J, Nasa Z, Lock P, Yap F, Toh BH, Alderuccio F. Transplantation of bone marrow genetically engineered to express proinsulin II protects against autoimmune insulitis in NOD mice. J. Gene Med. 8: 1281-1290 (2006).
Chan MT, Owen P, Dunphy J, Cox B, Carmichael C, Korendowych E, McHugh NJ. Associations of erosive arthritis with anti-cyclic citrullinated peptide antibodies and MHC class II alleles in systemic lupus erythematosus. J. Rheumatol. 35: 77-83 (2008).
Chan-Ling T, Hughes S, Baxter L, Rosinova E, McGregor I, Morcos Y, van Nieuwenhuyzen P, Hu P. Inflammation and breakdown of the blood-retinal barrier during "physiological aging" in the rat retina: a model for CNS aging. Microcirculation 14: 63-76 (2007).
Chang CH, Flavell RA. Class II transactivator regulates the expression of multiple genes involved in antigen presentation. J. Exp. Med. 181: 765-767 (1995). *
Chang KY, Unanue ER. Prediction of HLA-DQ8 beta cell peptidome using a computational program and its relationship to autoreactive T cells. Int. Immunol. 21: 705-713 (2009).
Chang YC, Chen TC, Lee CT, Yang CY, Wang HW, Wang CC, Hsieh SL. Epigenetic control of MHC-II expression in tumor-associated macrophages by decoy receptor 3. Blood 111: 5054-5063 (2008). *
Chang YT, Chou CT, Yu CW, Lin MW, Shiao YM, Chen CC, Huang CH, Lee DD, Liu HN, Wang WJ, Tsai SF. Cytokine gene polymorphisms in Chinese patients with psoriasis. Br. J. Dermatol. 156: 899-905 (2007). *
Chang YT, Tsai SF, Lee DD, Shiao YM, Huang CY, Liu HN, Wang WJ, Wong CK. A study of candidate genes for psoriasis near HLA-C in Chinese patients with psoriasis. Br. J. Dermatol. 148: 418-423 (2003). *
Chao MJ, Barnardo MC, Bu GZ, Lincoln MR, Ramagopalan SV, Herrera BM, Dyment DA, Sadovnick AD, Ebers GC. Transmission of class I/II multi-locus MHC haplotypes and multiple sclerosis susceptibility: accounting for linkage disequilibrium. Hum. Mol. Genet. 16: 1951-1958 (2007). *
Chao MJ, Barnardo MC, Lincoln MR, Ramagopalan SV, Herrera BM, Dyment DA, Montpetit A, Sadovnick AD, Knight JC, Ebers GC. HLA class I alleles tag HLA-DRB1*1501 haplotypes for differential risk in multiple sclerosis susceptibility. Proc. Natl. Acad. Sci. U.S.A. 105: 13069-13074 (2008). *
Chao MJ, Ramagopalan SV, Herrera BM, Lincoln MR, Dyment DA, Sadovnick AD, Ebers GC. Epigenetics in multiple sclerosis susceptibility: difference in transgenerational risk localizes to the major histocompatibility complex. Hum. Mol. Genet. 18: 261-266 (2009).
Chaouat G, Petitbarat M, Bulla R, Dubanchet S, Valdivia K, Ledee N, Steffen T, Jensenius JC, Tedesco F. Early regulators in abortion and implications for a preeclampsia model. J. Reprod. Immunol. 82: 131-140 (2009).
Chaparro RJ, Burton AR, Serreze DV, Vignali DA, Dilorenzo TP. Rapid identification of MHC class I-restricted antigens relevant to autoimmune diabetes using retrogenic T cells. J. Immunol. Methods 335: 106-115 (2008). *
Chapman RW, Varghese Z, Gaul R, Patel G, Kokinon N, Sherlock S. Association of primary sclerosing cholangitis with HLA-B8. Gut 24: 38-41 (1983). *
Charerntantanakul W, Roth JA. Biology of porcine T lymphocytes. Anim. Health Res. Rev. 7: 81-96 (2006). *
Charrier L, Merlin D. The oligopeptide transporter hPepT1: gateway to the innate immune response. Lab. Invest. 86: 538-546 (2006). *
Charron D. Immunogenomics of hematopoietic stem cell transplantation. Pathol. Biol. (Paris) 53: 171-173 (2005).
Chaturvedi UC, Nagar R, Shrivastava R. Macrophage & dengue virus: friend or foe? Indian J. Med. Res. 124: 23-40 (2006).
Chaudhury C, Kim J, Mehnaz S, Wani MA, Oberyszyn TM, Bronson CL, Mohanty S, Hayton WL, Robinson JM, Anderson CL. Accelerated transferrin degradation in HFE-deficient mice is associated with increased transferrin saturation. J. Nutr. 136: 2993-2998 (2006). *
Che C, Pang X, Hua X, Zhang B, Shen J, Zhu J, Wei H, Sun L, Chen P, Cui L, Zhao L, Yang Q. Effects of human fecal flora on intestinal morphology and mucosal immunity in human flora-associated piglet. Scand. J. Immunol. 69: 223-233 (2009). *
Chen C, Liu CP. Regulatory function of a novel population of mouse autoantigen-specific Foxp3 regulatory T cells depends on IFN-gamma, NO, and contact with target cells. PLoS One 4: e7863 (2009). *
Chen D, Radford-Smith G, Dipaolo MC, McGowan I, Jewell DP. Cytokine gene transcription of human colonic intraepithelial lymphocytes costimulated with epithelial cells bearing HLA-DR and its inhibition by 5-aminosalicylic acid. J. Clin. Immunol. 16: 237-241 (1996).
Chen G, Han G, Feng J, Wang J, Wang R, Xu R, Shen B, Qian J, Li Y. Glutamic acid decarboxylase-derived epitopes with specific domains expand CD4CD25 regulatory T cells. PLoS One 4: e7034 (2009). *
Chen JL, Morgan AJ, Stewart-Jones G, Shepherd D, Bossi G, Wooldridge L, Hutchinson SL, Sewell AK, Griffiths GM, van der Merwe PA, Jones EY, Galione A, Cerundolo V. Ca2+ release from the endoplasmic reticulum of NY-ESO-1-specific T cells is modulated by the affinity of TCR and by the use of the CD8 coreceptor. J. Immunol. Jan 6 [Epub ahead of print] (2010).
Chen L, Fredholm BB, Jondal M. Adenosine, through the A(1) receptor, inhibits vesicular MHC class I cross-presentation by resting DC. Mol. Immunol. 45: 2247-2254 (2008). *
Chen L, Jondal M. TLR9 activation increases TAP-independent vesicular MHC class I processing in vivo. Scand. J. Immunol. 70: 431-438 (2009). *
Chen MJ, Chu CC, Lin PY, Yang KL. Sequence-based typing of a novel HLA-DRB1*04 allele, DRB1*0461, in a Taiwanese volunteer marrow donor. Int. J. Immunogenet. 34: 269-272 (2007). *
Chen W, Cai MY, Wei DP, Wang X. Pivotal molecules of MHC I pathway in human primary hepatocellular carcinoma. World J. Gastroenterol. 11: 3297-3299 (2005). *
Chen W, Gluud C. Bile acids for liver transplanted patients. Cochrane Database Syst. Rev. 2: CD004384 (2004). *
Chen W, Gluud C. Bile acids for liver-transplanted patients. Cochrane Database Syst. Rev. 3: CD005442 (2005). *
Chen W, Zhang L, Liang B, Saenger Y, Li J, Chess L, Jiang H. Perceiving the avidity of T cell activation can be translated into peripheral T cell regulation. Proc. Natl. Acad. Sci. U.S.A. 104: 20472-20477 (2007). *
Chen WH, Lui CC, Chen CJ, Liu JS. An increase of anticardiolipin antibody in association with stroke and chronic chemical exposure. Clin. Appl. Thromb. Hemost. 12: 231-235 (2006).
Chen WH, Wang XX, Lin W, He XW, Wu ZQ, Lin Y, Hu SN, Wang XN. Analysis of 10,000 ESTs from lymphocytes of the cynomolgus monkey to improve our understanding of its immune system. BMC Genomics 7: 82 (2006). *
Chen X, Jensen PE. The expression of HLA-DO (H2-O) in B lymphocytes. Immunol. Res. 29: 19-28 (2004). *
Chen X, Jensen PE. MHC class II antigen presentation and immunological abnormalities due to deficiency of MHC class II and its associated genes. Exp. Mol. Pathol. 85: 40-44 (2008). *
Chen Y, Chong MM, Darwiche R, Thomas HE, Kay TW. Severe pancreatitis with exocrine destruction and increased islet neogenesis in mice with suppressor of cytokine signaling-1 deficiency. Am. J. Pathol. 165: 913-921 (2004). *
Chen Y, Gao F, Chu F, Peng H, Zong L, Liu Y, Tien P, Gao GF. Crystal structure of myeloid cell activating receptor leukocyte Ig-like receptor A2 (LILRA2/ILT1/LIR-7) domain swapped dimer: molecular basis for its non-binding to MHC complexes. J. Mol. Biol. 386: 841-853 (2009).
Chen Y, Jiang G, Yang HR, Gu X, Wang L, Hsieh CC, Chou HS, Fung JJ, Qian S, Lu L. Distinct response of liver myeloid dendritic cells to endotoxin is mediated by IL-27. J. Hepatol. 51: 510-519 (2009).
Chen Y, Shi Y, Cheng H, An YQ, Gao GF. Structural immunology and crystallography help immunologists see the immune system in action: how T and NK cells touch their ligands. IUBMB Life 61: 579-590 (2009). *
Chen YG, Scheuplein F, Osborne MA, Tsaih SW, Chapman HD, Serreze DV. The Idd9/11 genetic locus regulates diabetogenic activity of CD4 T-cells in non-obese diabetic (NOD) mice. Diabetes 57: 3273-3280 (2008). *
Chen YG, Silveira PA, Osborne MA, Chapman HD, Serreze DV. Cellular expression requirements for inhibition of type 1 diabetes by a dominantly protective major histocompatibility complex haplotype. Diabetes 56: 424-430 (2007). *
Chen YP, Pfab T, Slowinski T, Richter CM, Godes M, Hocher B. Impact of genetic variation of tumor necrosis factor-alpha on gestational hypertension. Chin. Med. J. (Engl.) 119: 719-724 (2006). *
Chen YT, Li S, Nikulina K, Porco T, Gallup M, McNamara N. Immune profile of squamous metaplasia development in autoimmune regulator-deficient dry eye. Mol. Vis. 15: 563-576 (2009). *
Chen YX, Man K, Ling GS, Chen Y, Sun BS, Cheng Q, Wong OH, Lo CK, Ng IO, Chan LC, Lau GK, Lin CL, Huang F, Huang FP. A crucial role for dendritic cell (DC) IL-10 in inhibiting successful DC-based immunotherapy: superior antitumor immunity against hepatocellular carcinoma evoked by DC devoid of IL-10. J. Immunol. 179: 6009-6015 (2007). *
Cheng L, Zhang SZ, Xiao CY, Hou YP, Li L, Luo HC, Jiang HY, Zuo WQ. The A5.1 allele of the major histocompatibility complex class I chain-related gene A is associated with psoriasis vulgaris in Chinese. Br. J. Dermatol. 143: 324-329 (2000).
Cheong KY, Allcock RJ, Eerligh P, Witt CS, Christiansen FT, McCann V, Price P. Localization of central MHC genes influencing type I diabetes. Hum. Immunol. 62: 1363-1370 (2001).
Chervin AS, Stone JD, Holler PD, Bai A, Chen J, Eisen HN, Kranz DM. The impact of TCR-binding properties and antigen presentation format on T cell responsiveness. J. Immunol. 183: 1166-1178 (2009).
Cheuk E, D'Souza C, Hu N, Liu Y, Lang H, Chamberlain JW. Human MHC class I transgenic mice deficient for H2 class I expression facilitate identification and characterization of new HLA class I-restricted viral T cell epitopes. J. Immunol. 169: 5571-5580 (2002). *
Cheung YK, Cheng SC, Sin FW, Chan KT, Xie Y. Induction of T-cell response by a DNA vaccine encoding a novel HLA-A*0201 severe acute respiratory syndrome coronavirus epitope. Vaccine 25: 6070-6077 (2007).
Cheunsuk S, Lian ZX, Yang GX, Gershwin ME, Gruen JR, Bowlus CL. Prss16 is not required for T-cell development. Mol. Cell. Biol. 25: 789-796 (2005). *
Chiang HI, Zhou H, Raudsepp T, Jesudhasan PR, Zhu JJ. Chicken CD69 and CD94/NKG2-like genes in a chromosomal region syntenic to mammalian natural killer gene complex. Immunogenetics 59: 603-611 (2007). *
Chien YH, Konigshofer Y. Antigen recognition by gammadelta T cells. Immunol. Rev. 215: 46-58 (2007). *
Chieppa M, Rescigno M, Huang AY, Germain RN. Dynamic imaging of dendritic cell extension into the small bowel lumen in response to epithelial cell TLR engagement. J. Exp. Med. 203: 2841-2852 (2006). *
Childers CP, Newkirk HL, Honeycutt DA, Ramlachan N, Muzney DM, Sodergren E, Gibbs RA, Weinstock GM, Womack JE, Skow LC. Comparative analysis of the bovine MHC class IIb sequence identifies inversion breakpoints and three unexpected genes. Anim. Genet. 37: 121-129 (2006). *
Chinnery HR, Ruitenberg MJ, Plant GW, Pearlman E, Jung S, McMenamin PG. The chemokine receptor CX3CR1 mediates homing of MHC class II-positive cells to the normal mouse corneal epithelium. Invest. Ophthalmol. Vis. Sci. 48: 1568-1574 (2007). *
Chinoy H, Lamb JA, Ollier WE, Cooper RG. An update on the immunogenetics of idiopathic inflammatory myopathies: major histocompatibility complex and beyond. Curr. Opin. Rheumatol. 21: 588-593 (2009).
Cho J. Update on inflammatory bowel disease genetics. Curr. Gastroenterol. Rep. 2: 434-439 (2000).
Cho JH. Update on the genetics of inflammatory bowel disease. Curr. Gastroenterol. Rep. 3: 458-463 (2001).
Choi J, Enis DR, Koh KP, Shiao SL, Pober JS. T lymphocyte-endothelial cell interactions. Annu. Rev. Immunol. 22: 683-709 (2004). *
Chong AS. Receptors that turn on and turn off natural killer cells. J. Heart Lung Transplant. 15: 675-683 (1996).
Choo SY. The HLA system: genetics, immunology, clinical testing, and clinical implications. Yonsei Med. J. 48: 11-23 (2007). *
Choonhakarn C, Romphruk A, Puapairoj C, Jirarattanapochai K, Romphruk A, Leelayuwat C. Haplotype associations of the major histocompatibility complex with psoriasis in Northeastern Thais. Int. J. Dermatol. 41: 330-334 (2002).
Chora AA, Fontoura P, Cunha A, Pais TF, Cardoso S, Ho PP, Lee LY, Sobel RA, Steinman L, Soares MP. Heme oxygenase-1 and carbon monoxide suppress autoimmune neuroinflammation. J. Clin. Invest. 117: 438-447 (2007). *
Chow AY, Mellman I. Old lysosomes, new tricks: MHC II dynamics in DCs. Trends Immunol. 26: 72-78 (2005). *
Chowdhury ZM, McDermott MF, Davey S, Hassan Z, Sinnott PJ, Hemmatpour SK, Sherwin S, Ali L, Aganna E, Allotey RA, North BV, Cassell PG, Azad Khan AK, Hitman GA. Genetic susceptibility to fibrocalculous pancreatic diabetes in Bangladeshi subjects: a family study. Genes Immun. 3: 5-8 (2002). *
Choy E. T cells in psoriatic arthritis. Curr. Rheumatol. Rep. 9: 437-441 (2007).
Choy MK, Phipps ME. MICA polymorphism: biology and importance in immunity and disease. Trends Mol. Med. Feb 11 [Epub ahead of print] (2010). *
Christadoss P. Immunogenetics of experimental autoimmune myasthenia gravis. Crit. Rev. Immunol. 9: 247-278 (1989).
Christadoss P, Poussin M, Deng C. Animal models of myasthenia gravis. Clin. Immunol. 94: 75-87 (2000). *
Christiansen FT, Saueracker GC, Leaver AL, Tokunaga K, Cameron PU, Dawkins RL. Characterization of MHC ancestral haplotypes associated with insulin-dependent diabetes mellitus: evidence for involvement of non-HLA genes. J. Immunogenet. 17: 379-386 (1990).
Christiansen FT, Zhang WJ, Griffiths M, Mallal SA, Dawkins RL. Major histocompatibility complex (MHC) complement deficiency, ancestral haplotypes and systemic lupus erythematosus (SLE): C4 deficiency explains some but not all of the influence of the MHC. J. Rheumatol. 18: 1350-1358 (1991).
Chui CS, Li D, Xu XN. The role of ILT family receptors and their ligands in suppressor T cell-induced dendritic cell tolerisation. Hum. Immunol. 70: 686-691 (2009).
Chung EK, Wu YL, Yang Y, Zhou B, Yu CY. Human complement components C4A and C4B genetic diversities: complex genotypes and phenotypes. Curr. Protoc. Immunol. Chapter 13: Unit 13.8 (2005).
Ciccocioppo R, Rossi M, Pesce I, Ricci G, Millimaggi D, Maurano F, Corazza GR. Effects of gliadin stimulation on bone marrow-derived dendritic cells from HLA-DQ8 transgenic mice. Dig. Liver Dis. 40: 927-935 (2008).
Cicinnati VR, Zhang X, Yu Z, Ferencik S, Schmitz KJ, Dworacki G, Kaczmarek E, Oldhafer K, Frilling A, Baba HA, Schmid KW, Grosse-Wilde H, Broelsch CE, Deleo AB, Gerken G, Beckebaum S. Increased frequencies of CD8+ T lymphocytes recognizing wild-type p53-derived epitopes in peripheral blood correlate with presence of epitope loss tumor variants in patients with hepatocellular carcinoma. Int. J. Cancer 119: 2851-2860 (2006). *
Cina RA, Wikiel KJ, Lee PW, Cameron AM, Hettiarachy S, Rowland H, Goodrich J, Colby C, Spitzer TR, Neville DM Jr, Huang CA. Stable multilineage chimerism without graft versus host disease following nonmyeloablative haploidentical hematopoietic cell transplantation. Transplantation 81: 1677-1685 (2006).
Cirulli V, Zalatan J, McMaster M, Prinsen R, Salomon DR, Ricordi C, Torbett BE, Meda P, Crisa L. The class I HLA repertoire of pancreatic islets comprises the nonclassical class Ib antigen HLA-G. Diabetes 55: 1214-1222 (2006). *
Ciurli C, Posnett DN, Sekaly RP, Denis F. Highly biased CDR3 usage in restricted sets of beta chain variable regions during viral superantigen 9 response. J. Exp. Med. 187: 253-258 (1998). *
Clavijo-Alvarez JA, Hamad GG, Taieb A, Lee WP. Pharmacologic approaches to composite tissue allograft. J. Hand Surg. [Am.] 32: 104-118 (2007).
Clayton RF, Rinaldi A, Kandyba EE, Edward M, Willberg C, Klenerman P, Patel AH. Liver cell lines for the study of hepatocyte functions and immunological response. Liver Int. 25: 389-402 (2005). *
Clements CS, Dunstone MA, Macdonald WA, McCluskey J, Rossjohn J. Specificity on a knife-edge: the alphabeta T cell receptor. Curr. Opin. Struct. Biol. 16: 787-795 (2006). *
Clements CS, Kjer-Nielsen L, Kostenko L, McCluskey J, Rossjohn J. The production, purification and crystallization of a soluble form of the nonclassical MHC HLA-G: the essential role of cobalt. Acta Crystallograph. Sect. F. Struct. Biol. Cryst. Commun. 62: 70-73 (2006). *
Clements CS, Kjer-Nielsen L, McCluskey J, Rossjohn J. Structural studies on HLA-G: implications for ligand and receptor binding. Hum. Immunol. 68: 220-226 (2007).
Coakley G, Brooks D, Iqbal M, Kondeatis E, Vaughan R, Loughran TP Jr, Panayi GS, Lanchbury JS. Major histocompatility complex haplotypic associations in Felty's syndrome and large granular lymphocyte syndrome are secondary to allelic association with HLA-DRB1 *0401. Rheumatology (Oxford) 39: 393-398 (2000). *
Cobain TJ, French MA, Christiansen FT, Dawkins RL. Association of IgA deficiency with HLA A28 and B14. Tissue Antigens 22: 151-154 (1983).
Cobain TJ, Stuckey MS, McCluskey J, Wilton AN, Gedeon A, Garlepp MJ, Christiansen FT, Dawkins RL. The coexistence of IgA deficiency and 21-hydroxylase deficiency marked by specific MHC supratypes. Ann. N. Y. Acad. Sci. 458: 76-84 (1985). *
Cobb BA, Kasper DL. Coming of age: carbohydrates and immunity. Eur. J. Immunol. 35: 352-356 (2005). *
Cobb BA, Kasper DL. Zwitterionic capsular polysaccharides: the new MHCII-dependent antigens. Cell. Microbiol. 7: 1398-1403 (2005). *
Cobb BA, Kasper DL. Characteristics of carbohydrate antigen binding to the presentation protein HLA-DR. Glycobiology 18: 707-718 (2008). *
Coffman FD. Chitinase 3-like-1 (CHI3L1): a putative disease marker at the interface of proteomics and glycomics. Crit. Rev. Clin. Lab. Sci. 45: 531-562 (2008).
Cohen R, Metzger S, Nahir M, Chajek-Shaul T. Association of the MIC-A gene and HLA-B51 with Behcet's disease in Arabs and non-Ashkenazi Jews in Israel. Ann. Rheum. Dis. 61: 157-160 (2002). *
Cohly HH, Panja A. Immunological findings in autism. Int. Rev. Neurobiol. 71: 317-341 (2005).
Cohn M. On a key postulate of T-cell receptor restrictive function: the V-gene loci act as a single pool encoding recognition of the polymorphic alleles of the species major histocompatibility complex. Immunology 120: 140-142 (2007). *
Cole DK, Gao GF. CD8: adhesion molecule, co-receptor and immuno-modulator. Cell. Mol. Immunol. 1: 81-88 (2004). *
Cole DK, Rizkallah PJ, Sami M, Lissin NM, Gao F, Bell JI, Boulter JM, Glick M, Vuidepot AL, Jakobsen BK, Gao GF. Crystallization and preliminary X-ray structural studies of a high-affinity CD8alphaalpha co-receptor to pMHC. Acta Crystallograph. Sect. F. Struct. Biol. Cryst. Commun. 61: 285-287 (2005). *
Coleman SH, Madrid R, Van Damme N, Mitchell RS, Bouchet J, Servant C, Pillai S, Benichou S, Guatelli JC. Modulation of cellular protein trafficking by human immunodeficiency virus type 1 Nef: role of the acidic residue in the ExxxLL motif. J. Virol. 80: 1837-1849 (2006). *
Colf LA, Bankovich AJ, Hanick NA, Bowerman NA, Jones LL, Kranz DM, Garcia KC. How a single T cell receptor recognizes both self and foreign MHC. Cell 129: 135-146 (2007). *
Collier PM, Wojnarowska F, Welsh K, McGuire W, Black MM. Adult linear IgA disease and chronic bullous disease of childhood: the association with human lymphocyte antigens Cw7, B8, DR3 and tumour necrosis factor influences disease expression. Br. J. Dermatol. 141: 867-875 (1999).
Collins RW, Stephens HA, Clare MA, Vaughan RW. High resolution molecular phototyping of MICA and MICB alleles using sequence specific primers. Hum. Immunol. 63: 783-794 (2002).
Colmone A, Wang CR. H2-M3-restricted T cell response to infection. Microbes Infect. 8: 2277-2283 (2006). *
Colonna M. TREMs in the immune system and beyond. Nat. Rev. Immunol. 3: 445-453 (2003). *
Colonna M. Natural killer cell receptors specific for MHC class I molecules. Curr. Opin. Immunol. 8: 101-107 (1996).
Colonna M, Bresnahan M, Bahram S, Strominger JL, Spies T. Allelic variants of the human putative peptide transporter involved in antigen processing. Proc. Natl. Acad. Sci. U.S.A. 89: 3932-3936 (1992). *
Comin-Anduix B, Gualberto A, Glaspy JA, Seja E, Ontiveros M, Reardon DL, Renteria R, Englahner B, Economou JS, Gomez-Navarro J, Ribas A. Definition of an immunologic response using the major histocompatibility complex tetramer and enzyme-linked immunospot assays. Clin. Cancer Res. 12: 107-116 (2006). *
Concannon P, Erlich HA, Julier C, Morahan G, Nerup J, Pociot F, Todd JA, Rich SS. Type 1 diabetes: evidence for susceptibility loci from four genome-wide linkage scans in 1,435 multiplex families. Diabetes 54: 2995-3001 (2005). *
Cong Y, Bowdon HR, Elson CO. Identification of an immunodominant T cell epitope on cholera toxin. Eur. J. Immunol. 26: 2587-2594 (1996).
Cong Y, Brandwein SL, McCabe RP, Lazenby A, Birkenmeier EH, Sundberg JP, Elson CO. CD4+ T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: increased T helper cell type 1 response and ability to transfer disease. J. Exp. Med. 187: 855-864 (1998). *
Cong Y, Weaver CT, Lazenby A, Elson CO. Bacterial-reactive T regulatory cells inhibit pathogenic immune responses to the enteric flora. J. Immunol. 169: 6112-6119 (2002). *
Connolly MK, Bedrosian AS, Mallen-St Clair J, Mitchell AP, Ibrahim J, Stroud A, Pachter HL, Bar-Sagi D, Frey AB, Miller G. In liver fibrosis, dendritic cells govern hepatic inflammation in mice via TNF-alpha. J. Clin. Invest. 119: 3213-3225 (2009). *
Conrad B, Weissmahr RN, Boni J, Arcari R, Schupbach J, Mach B. A human endogenous retroviral superantigen as candidate autoimmune gene in type I diabetes. Cell 90: 303-313 (1997). *
Constabel H, Stankov MV, Hartwig C, Tschernig T, Behrens GM. Impaired lung dendritic cell migration and T cell stimulation induced by immunostimulatory oligonucleotides contribute to reduced allergic airway inflammation. J. Immunol. 183: 3443-3453 (2009).
Conti L, Cardone M, Varano B, Puddu P, Belardelli F, Gessani S. Role of the cytokine environment and cytokine receptor expression on the generation of functionally distinct dendritic cells from human monocytes. Eur. J. Immunol. 38: 750-762 (2008). *
Contu L, Orru S, Carcassi C, Giuressi E, Mulargia M, Cappai L, Valentini D, Lai S, Boero R, Masala MV, Aste N, Biggio P, Cottoni F, Cerimele D. A psoriasis vulgaris protective gene maps close to the HLA-C locus on the EH18.2-extended haplotype. Tissue Antigens 64: 43-57 (2004). *
Cookson S, Constantini PK, Clare M, Underhill JA, Bernal W, Czaja AJ, Donaldson PT. Frequency and nature of cytokine gene polymorphisms in type 1 autoimmune hepatitis. Hepatology 30: 851-856 (1999). *
Cookson WO, Moffatt MF. Genetics of asthma and allergic disease. Hum. Mol. Genet. 9: 2359-2364 (2000). *
Cooney R, Baker J, Brain O, Danis B, Pichulik T, Allan P, Ferguson DJ, Campbell BJ, Jewell D, Simmons A. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat. Med. 16: 90-97 (2010). *
Cooper GS, Miller FW, Pandey JP. The role of genetic factors in autoimmune disease: implications for environmental research. Environ. Health Perspect. 107 Suppl. 5: 693-700 (1999).
Corper AL, Stratmann T, Apostolopoulos V, Scott CA, Garcia KC, Kang AS, Wilson IA, Teyton L. A structural framework for deciphering the link between I-Ag7 and autoimmune diabetes. Science 288: 505-511 (2000). *
Correa MC, Memije EV, Vargas-Alarcon G, Guzman RA, Rosetti F, Acuna-Alonzo V, Martinez-Rodriguez N, Granados J. HLA-DR association with the genetic susceptibility to develop ashy dermatosis in Mexican Mestizo patients. J. Am. Acad. Dermatol. 56: 617-620 (2007).
Correia AP, Pinto JP, Dias V, Mascarenhas C, Almeida S, Porto G. CAT53 and HFE alleles in Alzheimer's disease: a putative protective role of the C282Y HFE mutation. Neurosci. Lett. 457: 129-132 (2009).
Cortesini R, Suciu-Foca N. ILT3+ ILT4+ tolerogenic endothelial cells in transplantation. Transplantation 82 Suppl. 1: S30-S32 (2006).
Corthay A. A three-cell model for activation of naive T helper cells. Scand. J. Immunol. 64: 93-96 (2006). *
Corzo D, Salazar M, Granja CB, Yunis EJ. Advances in HLA genetics. Exp. Clin. Immunogenet. 12: 156-170 (1995).
Corzo D, Yunis JJ, Salazar M, Lieberman JA, Howard A, Awdeh Z, Alper CA, Yunis EJ. The major histocompatibility complex region marked by HSP70-1 and HSP70-2 variants is associated with clozapine-induced agranulocytosis in two different ethnic groups. Blood 86: 3835-3840 (1995). *
Costantino CM, Ploegh HL, Hafler DA. Cathepsin S regulates class II MHC processing in human CD4+ HLA-DR+ T cells. J. Immunol. 183: 945-952 (2009).
Costello P, FitzGerald O. Disease mechanisms in psoriasis and psoriatic arthritis. Curr. Rheumatol. Rep. 3: 419-427 (2001).
Cottier H, Hassig A. Immunoglobulin in chronic inflammatory diseases. Vox. Sang. 51 Suppl. 2: 39-43 (1986).
Coupel S, Moreau A, Hamidou M, Horejsi V, Soulillou JP, Charreau B. Expression and release of soluble HLA-E is an immunoregulatory feature of endothelial cell activation. Blood 109: 2806-2814 (2007). *
Coyle AJ, Gutierrez-Ramos JC. The role of ICOS and other costimulatory molecules in allergy and asthma. Springer Semin. Immunopathol. 25: 349-359 (2004). *
Cragnolini JJ, Garcia-Medel N, Lopez de Castro JA. Endogenous processing and presentation of T-cell epitopes from Chlamydia trachomatis with relevance in HLA-B27-associated reactive arthritis. Mol. Cell. Proteomics 8: 1850-1859 (2009). *
Craig D, Robins G, Howdle PD. Advances in celiac disease. Curr. Opin. Gastroenterol. 23: 142-148 (2007).
Crawford F, Jordan KR, Stadinski B, Wang Y, Huseby E, Marrack P, Slansky JE, Kappler JW. Use of baculovirus MHC/peptide display libraries to characterize T-cell receptor ligands. Immunol. Rev. 210: 156-170 (2006). *
Creary LE, Girdlestone J, Zamora J, Brown J, Navarrete CV. Molecular typing of HLA genes using whole genome amplified DNA. Transfusion 49: 57-63 (2009).
Crespo HJ, Cabral MG, Teixeira AV, Lau JT, Trindade H, Videira PA. Effect of sialic acid loss on dendritic cell maturation. Immunology 128: e621-e631 (2009).
Cresswell P. Cell biology. Cutting and pasting antigenic peptides. Science 304: 525-527 (2004). *
Creusot RJ, Fathman CG. Gene therapy for type 1 diabetes: a novel approach for targeted treatment of autoimmunity. J. Clin. Invest. 114: 892-894 (2004). *
Creusot RJ, Yaghoubi SS, Kodama K, Dang DN, Dang VH, Breckpot K, Thielemans K, Gambhir SS, Fathman CG. Tissue-targeted therapy of autoimmune diabetes using dendritic cells transduced to express IL-4 in NOD mice. Clin. Immunol. 127: 176-187 (2008). *
Crew RJ, Ratner LE. Overcoming immunologic incompatibility: transplanting the difficult to transplant patient. Semin. Dial. 18: 474-481 (2005).
Crispim JC, Mendes-Junior CT, Wastowski IJ, Costa R, Castelli EC, Saber LT, Donadi EA. Frequency of insertion/deletion polymorphism in exon 8 of HLA-G and kidney allograft outcome. Tissue Antigens 71: 35-41 (2008). *
Crotzer VL, Blum JS. Autophagy and its role in MHC-mediated antigen presentation. J. Immunol. 182: 3335-3341 (2009).
Croxford JL, Ercolini AM, Degutes M, Miller SD. Structural requirements for initiation of cross-reactivity and CNS autoimmunity with a PLP(139-151) mimic peptide derived from murine hepatitis virus. Eur. J. Immunol. 36: 2671-2680 (2006). *
Croxford JL, Miyake S, Huang YY, Shimamura M, Yamamura T. Invariant V(alpha)19i T cells regulate autoimmune inflammation. Nat. Immunol. 7: 987-994 (2006). *
Cruickshank SM, English NR, Felsburg PJ, Carding SR. Characterization of colonic dendritic cells in normal and colitic mice. World J. Gastroenterol. 11: 6338-6347 (2005). *
Cruickshank SM, Southgate J, Selby PJ, Trejdosiewicz LK. Expression and cytokine regulation of immune recognition elements by normal human biliary epithelial and established liver cell lines in vitro. J. Hepatol. 29: 550-558 (1998). *
Cruz E, Vieira J, Goncalves R, Alves H, Almeida S, Rodrigues P, Lacerda R, Porto G. Involvement of the major histocompatibility complex region in the genetic regulation of circulating CD8 T-cell numbers in humans. Tissue Antigens 64: 25-34 (2004). *
Cucca F, Congia M, Trowsdale J, Powis SH. Insulin-dependent diabetes mellitus and the major histocompatibility complex peptide transporters TAP1 and TAP2: no association in a population with a high disease incidence. Tissue Antigens 44: 234-240 (1994).
Cucca F, Contu D, Zavattari P, Murru D. Correlation between major histocompatibility complex (MHC)-class II and type 1 diabetes. Minerva Endocrinol. 28: 111-122 (2003).
Cucca F, Dudbridge F, Loddo M, Mulargia AP, Lampis R, Angius E, De Virgiliis S, Koeleman BP, Bain SC, Barnett AH, Gilchrist F, Cordell H, Welsh K, Todd JA. The HLA-DPB1-associated component of the IDDM1 and its relationship to the major loci HLA-DQB1, -DQA1, and -DRB1. Diabetes 50: 1200-1205 (2001). *
Cucca F, Lampis R, Congia M, Angius E, Nutland S, Bain SC, Barnett AH, Todd JA. A correlation between the relative predisposition of MHC class II alleles to type 1 diabetes and the structure of their proteins. Hum. Mol. Genet. 10: 2025-2037 (2001). *
Cucca F, Zhu ZB, Khanna A, Cossu F, Congia M, Badiali M, Lampis R, Frau F, De Virgiliis S, Cao A, Arnone M, Piras P, Campbell RD, Cooper MD, Volanakis JE, Powis SH. Evaluation of IgA deficiency in Sardinians indicates a susceptibility gene is encoded within the HLA class III region. Clin. Exp. Immunol. 111: 76-80 (1998). *
Cuenca J, Martin-Sanz P, Alvarez-Barrientos AM, Bosca L, Goren N. Infiltration of inflammatory cells plays an important role in matrix metalloproteinase expression and activation in the heart during sepsis. Am. J. Pathol. 169: 1567-1576 (2006). *
Cui J, Han LY, Lin HH, Tang ZQ, Jiang L, Cao ZW, Chen YZ. MHC-BPS: MHC-binder prediction server for identifying peptides of flexible lengths from sequence-derived physicochemical properties. Immunogenetics 58: 607-613 (2006). *
Cui J, Taylor K, Destefano A, Criswell L, Izmailova E, Alex P, Roubenoff R, Plenge R, Weinblatt M, Shadick N, Karlson E. Genome wide association study of determinants of anti-cyclic citrullinated peptide antibody titer in adults with rheumatoid arthritis. Mol. Med. 15: 136-143 (2009). *
Cullen M, Malasky M, Harding A, Carrington M. High-density map of short tandem repeats across the human major histocompatibility complex. Immunogenetics 54: 900-910 (2003). *
Culotta VC, Lin SJ, Schmidt P, Klomp LW, Casareno RL, Gitlin J. Intracellular pathways of copper trafficking in yeast and humans. Adv. Exp. Med. Biol. 448: 247-254 (1999).
Cunningham-Rundles C, Fotino M, Rosina O, Peter JB. Selective IgA deficiency, IgG subclass deficiency, and the major histocompatibility complex. Clin. Immunol. Immunopathol. 61: S61-S69 (1991).
Curry AJ, Chikwe J, Smith XG, Cai M, Schwarz H, Bradley JA, Bolton EM. OX40 (CD134) blockade inhibits the co-stimulatory cascade and promotes heart allograft survival. Transplantation 78: 807-814 (2004).
Cuvelier C, Mielants H, De Vos M, Quatacker J, Veys E. Idiopathic inflammatory bowel diseases: immunological hypothesis. Acta Gastroenterol. Belg. 57: 292-299 (1994).
Cuvelier C, Mielants H, De Vos M, Veys E, Roels H. Major histocompatibility complex class II antigen (HLA-DR) expression by ileal epithelial cells in patients with seronegative spondylarthropathy. Gut 31: 545-549 (1990). *
Cycon KA, Clements JL, Holtz R, Fuji H, Murphy SP. The immunogenicity of L1210 lymphoma clones correlates with their ability to function as antigen-presenting cells. Immunology 128: e641-e651 (2009).
Czaja AJ. Autoimmune liver disease and rheumatic manifestations. Curr. Opin. Rheumatol. 19: 74-80 (2007).
Czaja AJ. Autoimmune hepatitis - approach to diagnosis. MedGenMed. 8: 55 (2006). *
Czaja AJ. Autoimmune liver disease. Curr. Opin. Gastroenterol. 23: 255-262 (2007).
Czaja AJ. Genetic factors affecting the occurrence, clinical phenotype, and outcome of autoimmune hepatitis. Clin. Gastroenterol. Hepatol. 6: 379-388 (2008).
Czaja AJ, Donaldson PT. Genetic susceptibilities for immune expression and liver cell injury in autoimmune hepatitis. Immunol. Rev. 174: 250-259 (2000). *
Czaja AJ, Shums Z, Donaldson PT, Norman GL. Frequency and significance of antibodies to Saccharomyces cerevisiae in autoimmune hepatitis. Dig. Dis. Sci. 49: 611-618 (2004). *
Czaja AJ, Strettell MD, Thomson LJ, Santrach PJ, Moore SB, Donaldson PT, Williams R. Associations between alleles of the major histocompatibility complex and type 1 autoimmune hepatitis. Hepatology 25: 317-323 (1997). *
D'Orsogna LJ, Amir AL, Zoet YM, van der Meer-Prins PM, van der Slik AR, Kester MG, Heemskerk MH, Doxiadis II, Roelen DL, Claas FH. New tools to monitor the impact of viral infection on the alloreactive T-cell repertoire. Tissue Antigens 74: 290-297 (2009). *
Dai S, Crawford F, Marrack P, Kappler JW. The structure of HLA-DR52c: comparison to other HLA-DRB3 alleles. Proc. Natl. Acad. Sci. U.S.A. 105: 11893-11897 (2008). *
Dai X, Jayapal M, Tay HK, Reghunathan R, Lin G, Too CT, Lim YT, Chan SH, Kemeny DM, Floto RA, Smith KG, Melendez AJ, Macary PA. Differential signal transduction, membrane trafficking and immune effector functions mediated by FcgammaRI versus FcgammaRIIa. Blood 114: 318-327 (2009). *
Dai YD, Marrero IG, Gros P, Zaghouani H, Wicker LS, Sercarz EE. Slc11a1 enhances the autoimmune diabetogenic T-cell response by altering processing and presentation of pancreatic islet antigens. Diabetes 58: 156-164 (2009). *
Dai Z, Turtle CJ, Booth GC, Riddell SR, Gooley TA, Stevens AM, Spies T, Groh V. Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus. J. Exp. Med. 206: 793-805 (2009). *
Dalai SK, Mirshahidi S, Morrot A, Zavala F, Sadegh-Nasseri S. Anergy in memory CD4+ T cells is induced by B cells. J. Immunol. 181: 3221-3231 (2008). *
Dalakas MC. Mechanisms of disease: signaling pathways and immunobiology of inflammatory myopathies. Nat. Clin. Pract. Rheumatol. 2: 219-227 (2006). *
Dalakas MC. Sporadic inclusion body myositis-diagnosis, pathogenesis and therapeutic strategies. Nat. Clin. Pract. Neurol. 2: 437-447 (2006). *
Dalakas MC. Inflammatory, immune, and viral aspects of inclusion-body myositis. Neurology 66: S33-S38 (2006).
Dalakas MC, Rakocevic G, Shatunov A, Goldfarb L, Raju R, Salajegheh M. Inclusion body myositis with human immunodeficiency virus infection: four cases with clonal expansion of viral-specific T cells. Ann. Neurol. 61: 466-475 (2007).
Dall'era MC, Cardarelli PM, Preston BT, Witte A, Davis JC. Type I interferon correlates with clinical and serologic manifestations of systemic lupus erythematosus. Ann. Rheum. Dis. 64: 1692-1697 (2005). *
Dalwadi H, Wei B, Kronenberg M, Sutton CL, Braun J. The Crohn's disease-associated bacterial protein I2 is a novel enteric T cell superantigen. Immunity 15: 149-158 (2001). *
Daly AK, Donaldson PT, Bhatnagar P, Shen Y, Pe'er I, Floratos A, Daly MJ, Goldstein DB, John S, Nelson MR, Graham J, Park BK, Dillon JF, Bernal W, Cordell HJ, Pirmohamed M, Aithal GP, Day CP; for the DILIGEN study; International SAE Consortium. HLA-B*5701 genotype is a major determinant of drug-induced liver injury due to flucloxacillin. Nat. Genet. 41: 816-819 (2009). *
Dam J, Baber J, Grishaev A, Malchiodi EL, Schuck P, Bax A, Mariuzza RA. Variable dimerization of the Ly49A natural killer cell receptor results in differential engagement of its MHC class I ligand. J. Mol. Biol. 362: 102-113 (2006). *
Damiani G, Campo I, Zorzetto M, Bozzi V, Disabella E, Caroli A, Ferrarotti I, D'Annunzio G, Pasi A, Martinetti M, Cuccia M. Pro-inflammatory variants of DRB1 and RAGE genes are associated with susceptibility to pediatric type 1 diabetes: a new hypothesis on the adaptive role of autoimmunity. Riv. Biol. 100: 285-304 (2007).
Dammeyer P, Mwakigonja AR, Rethi B, Chiodi F, Wolpert EZ. Vaccination with beta-microglobulin-deficient dendritic cells protects against growth of beta-microglobulin-deficient tumours. Scand. J. Immunol. 70: 44-52 (2009). *
Danielyan L, Tolstonog G, Traub P, Salvetter J, Gleiter CH, Reisig D, Gebhardt R, Buniatian GH. Colocalization of glial fibrillary acidic protein, metallothionein, and MHC II in human, rat, NOD/SCID, and nude mouse skin keratinocytes and fibroblasts. J. Invest. Dermatol. 127: 555-563 (2007). *
Dann SM, Wang HC, Gambarin KJ, Actor JK, Robinson P, Lewis DE, Caillat-Zucman S, White AC Jr. Interleukin-15 activates human natural killer cells to clear the intestinal protozoan Cryptosporidium. J. Infect. Dis. 192: 1294-1302 (2005). *
Dapprich J, Ferriola D, Magira EE, Kunkel M, Monos D. SNP-specific extraction of haplotype-resolved targeted genomic regions. Nucleic Acids Res. 36: e94 (2008). *
Darrasse-Jeze G, Deroubaix S, Mouquet H, Victora GD, Eisenreich T, Yao KH, Masilamani RF, Dustin ML, Rudensky A, Liu K, Nussenzweig MC. Feedback control of regulatory T cell homeostasis by dendritic cells in vivo. J. Exp. Med. 206: 1853-1862 (2009). *
Das A, Saxena RK. Role of interaction between Ly49 inhibitory receptors and cognate MHC I molecules in IL2-induced development of NK cells in murine bone marrow cell cultures. Immunol. Lett. 94: 209-214 (2004).
Das G, Das J, Eynott P, Zhang Y, Bothwell AL, Kaer LV, Shi Y. Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases. J. Exp. Med. 203: 2603-2611 (2006). *
Das KM. Immunopathogenesis of primary sclerosing cholangitis: possible role of a shared colonic and biliary epithelial antigen. J. Gastroenterol. Hepatol. 19: S290-S294 (2004). *
Das P, Abraham R, David C. HLA transgenic mice as models of human autoimmune diseases. Rev. Immunogenet. 2: 105-114 (2000).
Das P, Bradley DS, Geluk A, Griffiths MM, Luthra HS, David CS. An HLA-DRB1*0402 derived peptide (HV3 65-79) prevents collagen-induced arthritis in HLA-DQ8 transgenic mice. Hum. Immunol. 60: 575-582 (1999).
Dascher CC, Brenner MB. CD1 antigen presentation and infectious disease. Contrib. Microbiol. 10: 164-182 (2003).
Daser A, Mitchison H, Mitchison A, Muller B. Non-classical-MHC genetics of immunological disease in man and mouse. The key role of pro-inflammatory cytokine genes. Cytokine 8: 593-597 (1996).
Dash BP, Mukherjee S, Suhas VL, Chandra N. Interaction profiling of T-cell epitopes with MHC-class I molecules. Protein Pept. Lett. 14: 557-564 (2007).
Dastmalchi M, Grundtman C, Alexanderson H, Mavragani CP, Einarsdottir H, Barbasso Helmers S, Elvin K, Crow MK, Nennesmo I, Lundberg IE. A high incidence of disease flares in an open pilot study of infliximab in patients with refractory inflammatory myopathies. Ann. Rheum. Dis. 67: 1670-1677 (2008).
David CS, Taneja V. Role of major histocompatibility complex genes in murine collagen-induced arthritis: a model for human rheumatoid arthritis. Am. J. Med. Sci. 327: 180-187 (2004).
Davidson TS, Longnecker DS, Hickey WF. An experimental model of autoimmune pancreatitis in the rat. Am. J. Pathol. 166: 729-736 (2005). *
Davies CJ. Why is the fetal allograft not rejected? J. Anim. Sci. 85: E32-E35 (2007). *
Davies GE, Locke SM, Wright PW, Li H, Hanson RJ, Miller JS, Anderson SK. Identification of bidirectional promoters in the human KIR genes. Genes Immun. 8: 245-253 (2007). *
Davies JM. Molecular mimicry: can epitope mimicry induce autoimmune disease? Immunol. Cell Biol. 75: 113-126 (1997). *
Davies MN, Lamikanra A, Sansom CE, Flower DR, Moss DS, Travers PJ. Identification of the HLA-DM/HLA-DR interface. Mol. Immunol. 45: 1063-1070 (2008). *
Davis MM, Krogsgaard M, Huse M, Huppa JB, Lillemeier BF, Li QJ. T cells as a self-referential, sensory organ. Annu. Rev. Immunol. 25: 681-695 (2007). *
Dawe K, Hutchings P, Champion B, Cooke A, Roitt I. Autoantigens in thyroid diseases. Springer Semin. Immunopathol. 14: 285-307 (1993).
Dawkins R, Leelayuwat C, Gaudieri S, Tay G, Hui J, Cattley S, Martinez P, Kulski J. Genomics of the major histocompatibility complex: haplotypes, duplication, retroviruses and disease. Immunol. Rev. 167: 275-304 (1999).
Dawkins RL, Kay PH, Christiansen FT. Immunogenetics of rheumatoid arthritis. Ann. Acad. Med. Singapore 12: 155-163 (1983).
Dawkins RL, Martin E, Saueracker G, Kay PH, Leaver A, Christiansen FT. Supratypes and ancestral haplotypes in IDDM: potential importance of central non-HLA MHC genes. J. Autoimmun. 3 Suppl. 1: 63-68 (1990).
Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, Mackey EW, Miller JD, Leslie AJ, Depierres C, Mncube Z, Duraiswamy J, Zhu B, Eichbaum Q, Altfeld M, Wherry EJ, Coovadia HM, Goulder PJ, Klenerman P, Ahmed R, Freeman GJ, Walker BD. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature 443: 350-354 (2006). *
Day MJ. Immune system development in the dog and cat. J. Comp. Pathol. 137: S10-S15 (2007).
Day MJ. Canine sino-nasal aspergillosis: parallels with human disease. Med. Mycol. 47 Suppl. 1: S315-S323 (2009). *
Day SL, Ramsland PA, Apostolopoulos V. Non-canonical peptides bound to MHC. Curr. Pharm. Des. 15: 3274-3282 (2009).
Dazert E, Neumann-Haefelin C, Bressanelli S, Fitzmaurice K, Kort J, Timm J, McKiernan S, Kelleher D, Gruener N, Tavis JE, Rosen HR, Shaw J, Bowness P, Blum HE, Klenerman P, Bartenschlager R, Thimme R. Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response. J. Clin. Invest. 119: 376-386 (2009). *
de Bakker PI, McVean G, Sabeti PC, Miretti MM, Green T, Marchini J, Ke X, Monsuur AJ, Whittaker P, Delgado M, Morrison J, Richardson A, Walsh EC, Gao X, Galver L, Hart J, Hafler DA, Pericak-Vance M, Todd JA, Daly MJ, Trowsdale J, Wijmenga C, et al. A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC. Nat. Genet. 38: 1166-1172 (2006). *
De Gassart A, Camosseto V, Thibodeau J, Ceppi M, Catalan N, Pierre P, Gatti E. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. Proc. Natl. Acad. Sci. U.S.A. 105: 3491-3496 (2008). *
de Graaf KL, Barth S, Herrmann MM, Storch MK, Wiesmuller KH, Weissert R. Characterization of the encephalitogenic immune response in a model of multiple sclerosis. Eur. J. Immunol. 38: 299-308 (2008). *
de Haan EC, Moret EE, Wagenaar-Hilbers JP, Liskamp RM, Wauben MH. Possibilities and limitations in the rational design of modified peptides for T cell mediated immunotherapy. Mol. Immunol. 42: 365-373 (2005). *
de Jersey J, Snelgrove SL, Palmer SE, Teteris SA, Mullbacher A, Miller JF, Slattery RM. beta Cells cannot directly prime diabetogenic CD8 T cells in nonobese diabetic mice. Proc. Natl. Acad. Sci. U.S.A. 104: 1295-1300 (2007). *
de Kauwe AL, Chen Z, Anderson RP, Keech CL, Price JD, Wijburg O, Jackson DC, Ladhams J, Allison J, McCluskey J. Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells. J. Immunol. 182: 7440-7450 (2009).
de la Concha EG, Fernandez-Arquero M, Conejero L, Lazaro F, Mendoza JL, Sevilla MC, Diaz-Rubio M, Ruiz de Leon A. Presence of a protective allele for achalasia on the central region of the major histocompatibility complex. Tissue Antigens 56: 149-153 (2000). *
De la Concha EG, Fernandez-Arquero M, Gual L, Vigil P, Martinez A, Urcelay E, Ferreira A, Garcia-Rodriguez MC, Fontan G. MHC susceptibility genes to IgA deficiency are located in different regions on different HLA haplotypes. J. Immunol. 169: 4637-4643 (2002). *
de la Concha EG, Fernandez-Arquero M, Lopez-Nava G, Martin E, Allcock RJ, Conejero L, Paredes JG, Diaz-Rubio M. Susceptibility to severe ulcerative colitis is associated with polymorphism in the central MHC gene IKBL. Gastroenterology 119: 1491-1495 (2000). *
De la Concha EG, Fernandez-Arquero M, Vigil P, Lazaro F, Ferreira A, Garcia-Rodriguez MC, Fontan G. Tumor necrosis factor genomic polymorphism in Spanish IgA deficiency patients. Tissue Antigens 55: 359-363 (2000). *
de Lange P, Farina P, Moreno M, Ragni M, Lombardi A, Silvestri E, Burrone L, Lanni A, Goglia F. Sequential changes in the signal transduction responses of skeletal muscle following food deprivation. FASEB J. 20: 2579-2581 (2006). *
de Rijke B, van Horssen-Zoetbrood A, Veenbergen S, Fredrix H, de Witte T, van de Wiel-van Kemenade E, Dolstra H. Refinement of molecular approaches to improve the chance of identification of hematopoietic-restricted minor histocompatibility antigens. J. Immunol. Methods 329: 125-137 (2008). *
de Saint Jean M, Nakamura T, Wang Y, Trousdale MD, Schechter JE, Mircheff AK. Suppression of lymphocyte proliferation and regulation of dendritic cell phenotype by soluble mediators from rat lacrimal epithelial cells. Scand. J. Immunol. 70: 53-62 (2009). *
De Tomaso AW. Sea squirts and immune tolerance. Dis. Model Mech. 2: 440-445 (2009). *
De Tomaso AW, Nyholm SV, Palmeri KJ, Ishizuka KJ, Ludington WB, Mitchel K, Weissman IL. Isolation and characterization of a protochordate histocompatibility locus. Nature 438: 454-459 (2005). *
De Wall SL, Painter C, Stone JD, Bandaranayake R, Wiley DC, Mitchison TJ, Stern LJ, Dedecker BS. Noble metals strip peptides from class II MHC proteins. Nat. Chem. Biol. 2: 197-201 (2006). *
De Zorzi M, Caggiari L, Ahlenstiel G, Rehermann B, De Re V. Description of two new major histocompatibility complex (MHC) class II DRB1 [Pan troglodytes (Patr)-DRB1] alleles. Tissue Antigens 71: 490-492 (2008). *
Deakin JE, Papenfuss AT, Belov K, Cross JG, Coggill P, Palmer S, Sims S, Speed TP, Beck S, Marshall Graves JA. Evolution and comparative analysis of the MHC class III inflammatory region. BMC Genomics 7: 281 (2006). *
Dean G, Yeo TW, Goris A, Taylor CJ, Goodman RS, Elian M, Galea-Debono A, Aquilina A, Felice A, Vella M, Sawcer S, Compston DA. HLA-DRB1 and multiple sclerosis in Malta. Neurology 70: 101-105 (2008).
DeCicco KL, Youngdahl JD, Ross AC. All-trans-retinoic acid and polyriboinosinic : polyribocytidylic acid in combination potentiate specific antibody production and cell-mediated immunity. Immunology 104: 341-348 (2001). *
Deghaide NH, Rodrigues MD, Castelli EC, Mendes-Junior CT, Figueiredo JF, Donadi EA. Tumor necrosis factor region polymorphisms are associated with AIDS and with cytomegalovirus retinitis. AIDS 23: 1641-1647 (2009).
Degli-Esposti MA, Abraham LJ, McCann V, Spies T, Christiansen FT, Dawkins RL. Ancestral haplotypes reveal the role of the central MHC in the immunogenetics of IDDM. Immunogenetics 36: 345-356 (1992).
Degli-Esposti MA, Leelayuwat C, Dawkins RL. Ancestral haplotypes carry haplotypic and haplospecific polymorphisms of BAT1: possible relevance to autoimmune disease. Eur. J. Immunogenet. 19: 121-127 (1992).
del Fresno C, Garcia-Rio F, Gomez-Pina V, Soares-Schanoski A, Fernandez-Ruiz I, Jurado T, Kajiji T, Shu C, Marin E, Gutierrez del Arroyo A, Prados C, Arnalich F, Fuentes-Prior P, Biswas SK, Lopez-Collazo E. Potent phagocytic activity with impaired antigen presentation identifying lipopolysaccharide-tolerant human monocytes: demonstration in isolated monocytes from cystic fibrosis patients. J. Immunol. 182: 6494-6507 (2009).
Delaguillaumie A, Marin-Esteban V, Setterblad N, Leh LJ, Assier E, Gelin C, Charron D, Galy A, Mooney N. Contrasting cytoskeletal regulation of MHC class II peptide presentation by human B cells or dendritic cells. Eur. J. Immunol. 38: 1096-1105 (2008). *
Delgado-Vega AM, Anaya JM. Meta-analysis of HLA-DRB1 polymorphism in Latin American patients with rheumatoid arthritis. Autoimmun. Rev. 6: 402-408 (2007).
Deluca DS, Beisswanger E, Wermter J, Horn PA, Hahn U, Blasczyk R. MaHCO: an ontology of the major histocompatibility complex for immunoinformatic applications and text mining. Bioinformatics 25: 2064-2070 (2009).
Deluca DS, Blasczyk R. The immunoinformatics of cancer immunotherapy. Tissue Antigens 70: 265-271 (2007). *
DeLuca GC, Ramagopalan SV, Herrera BM, Dyment DA, Lincoln MR, Montpetit A, Pugliatti M, Barnardo MC, Risch NJ, Sadovnick AD, Chao M, Sotgiu S, Hudson TJ, Ebers GC. An extremes of outcome strategy provides evidence that multiple sclerosis severity is determined by alleles at the HLA-DRB1 locus. Proc. Natl. Acad. Sci. U.S.A. 104: 20896-20901 (2007). *
Demars JJ, Riquet JJ, Feve KK, Gautier MM, Morisson MM, Demeure OO, Renard CC, Chardon PP, Milan DD. High resolution physical map of porcine chromosome 7 QTL region and comparative mapping of this region among vertebrate genomes. BMC Genomics 7: 13 (2006). *
Demond AL, Starr T, Dustin ML, Groves JT. Control of antigen presentation with a photoreleasable agonist peptide. J. Am. Chem. Soc. 128: 15354-15355 (2006). *
Deng L, Mariuzza RA. Structural basis for recognition of MHC and MHC-like ligands by natural killer cell receptors. Semin. Immunol. 18: 159-166 (2006). *
Deng L, Mariuzza RA. Recognition of self-peptide-MHC complexes by autoimmune T-cell receptors. Trends Biochem. Sci. 32: 500-508 (2007). *
Depil S, Morales O, Castelli FA, Delhem N, Francois V, Georges B, Dufosse F, Morschhauser F, Hammer J, Maillere B, Auriault C, Pancre V. Determination of a HLA II promiscuous peptide cocktail as potential vaccine against EBV latency II malignancies. J. Immunother. 30: 215-226 (2007).
Depla E, Van der Aa A, Livingston BD, Crimi C, Allosery K, De Brabandere V, Krakover J, Murthy S, Huang M, Power S, Babe L, Dahlberg C, McKinney D, Sette A, Southwood S, Philip R, Newman MJ, Meheus L. Rational design of a multi-epitope vaccine encoding T-lymphocyte epitopes for treatment of chronic HBV infections. J. Virol. 82: 435-450 (2008). *
Depontieu FR, Qian J, Zarling AL, McMiller TL, Salay TM, Norris A, English AM, Shabanowitz J, Engelhard VH, Hunt DF, Topalian SL. Identification of tumor-associated, MHC class II-restricted phosphopeptides as targets for immunotherapy. Proc. Natl. Acad. Sci. U.S.A. 106: 12073-12078 (2009). *
Deretic V. Links between autophagy, innate immunity, inflammation and Crohn's disease. Dig. Dis. 27: 246-251 (2009).
Deretic V. Multiple regulatory and effector roles of autophagy in immunity. Curr. Opin. Immunol. 21: 53-62 (2009).
Desai SN, White DM, O'Shea KM, Brown ML, Cywin CL, Spero DM, Panzenbeck MJ. An orally active reversible inhibitor of cathepsin S inhibits human trans vivo delayed-type hypersensitivity. Eur. J. Pharmacol. 538: 168-174 (2006). *
Deshaies F, Diallo DA, Fortin JS, O'Rourke HM, Pezeshki AM, Bellemare-Pelletier A, Raby N, Bedard N, Brunet A, Denzin LK, Thibodeau J. Evidence for a human leucocyte antigen-DM-induced structural change in human leucocyte antigen-DObeta. Immunology 127: 408-417 (2009). *
Desombere I, Hauser P, Rossau R, Paradijs J, Leroux-Roels G. Nonresponders to hepatitis B vaccine can present envelope particles to T lymphocytes. J. Immunol. 154: 520-529 (1995).
Deviren G, Gupta K, Paulaitis ME, Schneck JP. Detection of antigen-specific T cells on p/MHC microarrays. J. Mol. Recognit. 20: 32-38 (2007). *
Diakite M, Clark TG, Auburn S, Campino S, Fry AE, Green A, Morris AP, Richardson A, Jallow M, Sisay-Joof F, Pinder M, Kwiatkowski DP, Rockett KA. A genetic association study in the Gambia using tagging polymorphisms in the major histocompatibility complex class III region implicates a HLA-B associated transcript 2 polymorphism in severe malaria susceptibility. Hum. Genet. 125: 105-109 (2009). *
Diao J, Zhao J, Winter E, Cattral MS. Recruitment and differentiation of conventional dendritic cell precursors in tumors. J. Immunol. Dec 21 [Epub ahead of print] (2009).
Diaz S, Echeverria MG, It V, Posik DM, Rogberg-Munoz A, Pena NL, Peral-Garcia P, Vega-Pla JL, Giovambattista G. Development of an ELA-DRA gene typing method based on pyrosequencing technology. Tissue Antigens 72: 464-468 (2008). *
Dickhaut K, Hoepner S, Eckhard J, Wiesmueller KH, Schindler L, Jung G, Falk K, Roetzschke O. Enhancement of tumour-specific immune responses in vivo by 'MHC loading-enhancer' (MLE). PLoS One 4: e6811 (2009). *
Diefenbach A, Raulet DH. Strategies for target cell recognition by natural killer cells. Immunol. Rev. 181: 170-184 (2001). *
Diefenbach A, Raulet DH. Natural killer cells: stress out, turn on, tune in. Curr. Biol. 9: R851-R853 (1999).
Diekmann J, Adamopoulou E, Beck O, Rauser G, Lurati S, Tenzer S, Einsele H, Rammensee HG, Schild H, Topp MS. Processing of two latent membrane protein 1 MHC class I epitopes requires tripeptidyl peptidase II involvement. J. Immunol. 183: 1587-1597 (2009).
Diepstra A, Poppema S, Boot M, Visser L, Nolte IM, Niens M, Te Meerman GJ, van den Berg A. HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin's lymphoma. Tissue Antigens 71: 219-226 (2008). *
Diez M, Abdelmagid N, Harnesk K, Strom M, Lidman O, Swanberg M, Lindblom R, Al-Nimer F, Jagodic M, Olsson T, Piehl F. Identification of gene regions regulating inflammatory microglial response in the rat CNS after nerve injury. J. Neuroimmunol. 212: 82-92 (2009).
Dijkstra IM, de Haas AH, Brouwer N, Boddeke HW, Biber K. Challenge with innate and protein antigens induces CCR7 expression by microglia in vitro and in vivo. Glia 54: 861-872 (2006).
Dikopoulos N, Wegenka U, Kroger A, Hauser H, Schirmbeck R, Reimann J. Recently primed CD8+ T cells entering the liver induce hepatocytes to interact with naive CD8+ T cells in the mouse. Hepatology 39: 1256-1266 (2004). *
Dilorenzo TP, Serreze DV. The good turned ugly: immunopathogenic basis for diabetogenic CD8 T cells in NOD mice. Immunol. Rev. 204: 250-263 (2005). *
Dimasi N, Biassoni R. Structural and functional aspects of the Ly49 natural killer cell receptors. Immunol. Cell Biol. 83: 1-8 (2005). *
Dimasi N, Moretta L, Biassoni R. Structure of the Ly49 family of natural killer (NK) cell receptors and their interaction with MHC class I molecules. Immunol. Res. 30: 95-104 (2004). *
Dimitri D, Dubourg O, Maisonobe T, Fournier E, Ranque B, Laforet P, Mussini JM, Pagnoux C, Behin A, Papo T, Benveniste O, Eymard B, Herson S. Distal inflammatory myopathy: unusual presentation of polymyositis or new entity? Neuromuscul. Disord. 18: 493-500 (2008).
Ding B, Padyukov L, Lundstrom E, Seielstad M, Plenge RM, Oksenberg JR, Gregersen PK, Alfredsson L, Klareskog L. Different patterns of associations with anti-citrullinated protein antibody-positive and anti-citrullinated protein antibody-negative rheumatoid arthritis in the extended major histocompatibility complex region. Arthritis Rheum. 60: 30-38 (2009). *
Ding L, Liang X, Zhu D, Lou Y. Peroxisome proliferator-activated receptor alpha is involved in cardiomyocyte differentiation of murine embryonic stem cells in vitro. Cell Biol. Int. 31: 1002-1009 (2007). *
Ding Y, Xia B, Lu M, Zhang Y, Li J, Ye M, Luo H, Yu J, Zhang X, Tan J. MHC class I chain-related gene A-A5.1 allele is associated with ulcerative colitis in Chinese population. Clin. Exp. Immunol. 142: 193-198 (2005). *
Diosdado B, van Oort E, Wijmenga C. "Coelionomics": towards understanding the molecular pathology of coeliac disease. Clin. Chem. Lab. Med. 43: 685-695 (2005). *
Dirosario J, Divers E, Wang C, Etter J, Charrier A, Jukkola P, Auer H, Best V, Newsom DL, McCarty DM, Fu H. Innate and adaptive immune activation in the brain of MPS IIIB mouse model. J. Neurosci. Res. 87: 978-990 (2009).
Dishaw LJ, Herrera ML, Bigger CH. Characterization and phylogenetic analysis of a cnidarian LMP X-like cDNA. Immunogenetics 58: 454-464 (2006). *
Dittmar M, Ide M, Wurm M, Kahaly GJ. Early onset of polyglandular failure is associated with HLA-DRB1*03. Eur. J. Endocrinol. 159: 55-60 (2008).
Dittmar M, Kahaly GJ. Immunoregulatory and susceptibility genes in thyroid and polyglandular autoimmunity. Thyroid 15: 239-250 (2005).
Dixon AM, Stanley BJ, Matthews EE, Dawson JP, Engelman DM. Invariant chain transmembrane domain trimerization: a step in MHC class II assembly. Biochemistry 45: 5228-534 (2006). *
Djilali-Saiah I, Benini V, Daniel S, Assan R, Bach JF, Caillat-Zucman S. Linkage disequilibrium between HLA class II (DR, DQ, DP) and antigen processing (LMP, TAP, DM) genes of the major histocompatibility complex. Tissue Antigens 48: 87-92 (1996).
Djilali-Saiah I, Benini V, Schmitz J, Timsit J, Assan R, Boitard C, Bach JF, Caillat-Zucman S. Absence of primary association between DM gene polymorphism and insulin-dependent diabetes mellitus or celiac disease. Hum. Immunol. 49: 22-27 (1996).
Djilali-Saiah I, Bertin E, Larger E, Timsit J, Assan R, Boitard C, Bach JF, Caillat-Zucman S. Major histocompatibility class II genes polymorphism in insulin dependent diabetes mellitus with or without associated thyroid autoimmunity. Hum. Immunol. 59: 176-182 (1998).
Djilali-Saiah I, Fakhfakh A, Louafi H, Caillat-Zucman S, Debray D, Alvarez F. HLA class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis. J. Hepatol. 45: 844-850 (2006). *
Djilali-Saiah I, Renous R, Caillat-Zucman S, Debray D, Alvarez F. Linkage disequilibrium between HLA class II region and autoimmune hepatitis in pediatric patients. J. Hepatol. 40: 904-909 (2004).
Djukic M, Mildner A, Schmidt H, Czesnik D, Bruck W, Priller J, Nau R, Prinz M. Circulating monocytes engraft in the brain, differentiate into microglia and contribute to the pathology following meningitis in mice. Brain 129: 2394-2403 (2006). *
Dlaske H, Karauzum H, Monzon-Casanova E, Rudolf R, Starick L, Muller I, Wildner G, Diedrichs-Mohring M, Koch N, Miyoshi-Akiyama T, Uchiyama T, Wonigeit K, Fleischer B, Overbeck S, Rink L, Herrmann T. Superantigen-presentation by rat major histocompatibility complex class II molecules RT1.Bl and RT1.Dl. Immunology 128: e572-e581 (2009).
Dobromylskyj M, Ellis S. Complexity in cattle KIR genes: transcription and genome analysis. Immunogenetics 59: 463-472 (2007). *
Doebis C, Schu S, Ladhoff J, Busch A, Beyer F, Reiser J, Nicosia RF, Broesel S, Volk HD, Seifert M. An anti-major histocompatibility complex class I intrabody protects endothelial cells from an attack by immune mediators. Cardiovasc. Res. 72: 331-338 (2006). *
Doherty DG, Underhill JA, Donaldson PT, Manabe K, Mieli-Vergani G, Eddleston AL, Vergani D, Demaine AG, Williams R. Polymorphism in the human complement C4 genes and genetic susceptibility to autoimmune hepatitis. Autoimmunity 18: 243-249 (1994).
Doherty PC. Challenged by complexity: my twentieth century in immunology. Annu. Rev. Immunol. 25: 1-19 (2007). *
Dohring C, Colonna M. Major histocompatibility complex (MHC) class I recognition by natural killer cells. Crit. Rev. Immunol. 17: 285-299 (1997).
Doisne JM, Castaigne JG, Deruyffelaere C, Dieu-Nosjean MC, Chamot C, Alcaide-Loridan C, Charron D, Al-Daccak R. The context of HLA-DR/CD18 complex in the plasma membrane governs HLA-DR-derived signals in activated monocytes. Mol. Immunol. 45: 709-718 (2008). *
Dolan BP, Li L, Takeda K, Bennink JR, Yewdell JW. Defective ribosomal products are the major source of antigenic peptides endogenously generated from influenza A virus neuraminidase. J. Immunol. Dec 28 [Epub ahead of print] (2009).
Dolgachev V, Petersen BC, Budelsky AL, Berlin AA, Lukacs NW. Pulmonary IL-17E (IL-25) production and IL-17RB+ myeloid cell-derived Th2 cytokine production are dependent upon stem cell factor-induced responses during chronic allergic pulmonary disease. J. Immunol. 183: 5705-5715 (2009).
Donadini R, Fields BA. Yersinia pseudotuberculosis superantigens. Chem. Immunol. Allergy 93: 77-91 (2007).
Donaghy L, Gros F, Amiot L, Mary C, Maillard A, Guiguen C, Gangneux JP. Elevated levels of soluble non-classical major histocompatibility class I molecule human leucocyte antigen (HLA)-G in the blood of HIV-infected patients with or without visceral leishmaniasis. Clin. Exp. Immunol. 147: 236-140 (2007). *
Donaldson DS, Williams NA. Bacterial toxins as immunomodulators. Adv. Exp. Med. Biol. 666: 1-18 (2009).
Donaldson P. HLA system and other genetic markers in PSC. Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper�s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 71-72. October 15-16 (2003). *
Donaldson PT. The role of genetics in immunopathogenesis. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 47-48 (2004). *
Donaldson PT. Immunogenetics in liver diseases. Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 23-24. September 12 - 13 (2003). *
Donaldson PT. Basic concepts in PSC. Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, pp. 73-75 (2005). *
Donaldson PT. Genetics in autoimmune hepatitis. Semin. Liver Dis. 22: 353-364 (2002). *
Donaldson PT. Chapter 17. Immunogenetics of autoimmune liver disease: risk factors for susceptibility and progression. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 221-234 (2007). *
Donaldson PT, Clare M, Constantini PK, Hadzic N, Mieli-Vergani G, Howard E, Kelley D. HLA and cytokine gene polymorphisms in biliary atresia. Liver 22: 213-219 (2002). *
Donaldson PT, Norris S. Immunogenetics in PSC. Best Pract. Res. Clin. Gastroenterol. 15: 611-627 (2001). *
Donaldson PT, Norris S. Evaluation of the role of MHC class II alleles, haplotypes and selected amino acid sequences in primary sclerosing cholangitis. Autoimmunity 35: 555-564 (2002).
Dong G, Wearsch PA, Peaper DR, Cresswell P, Reinisch KM. Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer. Immunity 30: 21-32 (2009). *
Dong Y, Denny TN. HLA-A2-restricted human CD8+ cytotoxic T lymphocyte responses to a novel epitope in vaccinia virus that is conserved among orthopox viruses. J. Infect. Dis. 194: 168-175 (2006). *
Donner H, Tonjes RR, Bontrop RE, Kurth R, Usadel KH, Badenhoop K. MHC diversity in Caucasians, investigated using highly heterogeneous noncoding sequence motifs at the DQB1 locus including a retroviral long terminal repeat element, and its comparison to nonhuman primate homologues. Immunogenetics 51: 898-904 (2000).
Donvito B, Monnet D, Tabary T, Delair E, Vittier M, Reveil B, Chiquet C, Brezin AP, Cohen JH. A new HLA extended haplotype containing the A*2910 allele is also associated with birdshot retinochoroidopathy and narrows susceptibility to the disease to the HLA molecule itself. Invest. Ophthalmol. Vis. Sci. Dec 3 [Epub ahead of print] (2009).
Dorak MT, Shao W, Machulla HK, Lobashevsky ES, Tang J, Park MH, Kaslow RA. Conserved extended haplotypes of the major histocompatibility complex: further characterization. Genes Immun. 7: 450-467 (2006). *
Dorph C, Englund P, Nennesmo I, Lundberg IE. Signs of inflammation in both symptomatic and asymptomatic muscles from patients with polymyositis and dermatomyositis. Ann. Rheum. Dis. 65: 1565-1571 (2006). *
Douin-Echinard V, Laffont S, Seillet C, Delpy L, Krust A, Chambon P, Gourdy P, Arnal JF, Guery JC. Estrogen receptor alpha, but not beta, is required for optimal dendritic cell differentiation and CD40-induced cytokine production. J. Immunol. 180: 3661-3669 (2008). *
Douroudis K, Nemvalts V, Rajasalu T, Kisand K, Uibo R. The CD226 gene in susceptibility of type 1 diabetes. Tissue Antigens 74: 417-419 (2009). *
Douroudis K, Tarassi K, Athanassiades T, Giannakopoulos F, Kominakis A, Thalassinos N, Papasteriades Ch. HLA alleles as predisposal factors for postmenopausal osteoporosis in a Greek population. Tissue Antigens 69: 592-596 (2007). *
Doxiadis GG, de Groot N, Bontrop RE. Impact of endogenous intronic retroviruses on major histocompatibility complex class II diversity and stability. J. Virol. 82: 6667-6677 (2008). *
Doxiadis GG, de Groot N, Claas FH, Doxiadis II, van Rood JJ, Bontrop RE. A highly divergent microsatellite facilitating fast and accurate DRB haplotyping in humans and rhesus macaques. Proc. Natl. Acad. Sci. U.S.A. 104: 8907-8912 (2007). *
Doxiadis GG, de Groot N, de Groot NG, Doxiadis II, Bontrop RE. Reshuffling of ancient peptide binding motifs between HLA-DRB multigene family members: old wine served in new skins. Mol. Immunol. 45: 2743-2751 (2008). *
Doxiadis GG, Heijmans CM, Otting N, Bontrop RE. MIC gene polymorphism and haplotype diversity in rhesus macaques. Tissue Antigens 69: 212-219 (2007). *
Doytchinova IA, Flower DR. In silico identification of supertypes for class II MHCs. J. Immunol. 174: 7085-7095 (2005). *
Doytchinova IA, Flower DR. Predicting class I major histocompatibility complex (MHC) binders using multivariate statistics: comparison of discriminant analysis and multiple linear regression. J. Chem. Inf. Model. 47: 234-238 (2007). *
Dragun D, Hegner B. Non-HLA antibodies post-transplantation: clinical relevance and treatment in solid organ transplantation. Contrib. Nephrol. 162: 129-139 (2009).
Drake CG, Kotzin BL. Superantigens: biology, immunology, and potential role in disease. J. Clin. Immunol. 12: 149-162 (1992).
Drakes M, Blanchard T, Czinn S. Bacterial probiotic modulation of dendritic cells. Infect. Immun. 72: 3299-3309 (2004). *
Dranitzki-Elhalel M, Huang JH, Rachmilewitz J, Pappo O, Parnas M, Schmidt W, Tykocinski ML. CTLA-4.FasL inhibits allogeneic responses in vivo. Cell. Immunol. 239: 129-135 (2006). *
Draube A, Beyer M, Schumer S, Thomas RK, Tresckow BV, Koslowsky TC, Krieglstein CF, Schultze JL, Wolf J. Efficient activation of autologous tumor-specific T cells: a simple coculture technique of autologous dendritic cells compared to established cell fusion strategies in primary human colorectal carcinoma. J. Immunother. 30: 359-369 (2007).
Driver JP, Scheuplein F, Chen YG, Grier AE, Wilson SB, Serreze DV. iNKT-cell control of type-1 diabetes: a dendritic cell genetic decision of a silver bullet or Russian roulette. Diabetes Nov 10 [Epub ahead of print] (2009).
Drouin EE, Glickstein L, Kwok WW, Nepom GT, Steere AC. Searching for borrelial T cell epitopes associated with antibiotic-refractory Lyme arthritis. Mol. Immunol. 45: 2323-2332 (2008). *
Drumea-Mirancea M, Wessels JT, Muller CA, Essl M, Eble JA, Tolosa E, Koch M, Reinhardt DP, Sixt M, Sorokin L, Stierhof YD, Schwarz H, Klein G. Characterization of a conduit system containing laminin-5 in the human thymus: a potential transport system for small molecules. J. Cell Sci. 119: 1396-1405 (2006). *
Du C, Sriram S. Induction of interleukin-12/p40 by superantigens in macrophages is mediated by activation of nuclear factor-kappaB. Cell. Immunol. 199: 50-57 (2000). *
Du L, Kijlstra A, Yang P. Immune response genes in uveitis. Ocul. Immunol. Inflamm. 17: 249-256 (2009).
Du QS, Wei YT, Pang ZW, Chou KC, Huang RB. Predicting the affinity of epitope-peptides with class I MHC molecule HLA-A*0201: an application of amino acid-based peptide prediction. Protein Eng. Des. Sel. 20: 417-423 (2007). *
Du Z, Gjertson DW, Reed EF, Rajalingam R. Receptor-ligand analyses define minimal killer cell Ig-like receptor (KIR) in humans. Immunogenetics 59: 1-15 (2007). *
Duan J, Avci FY, Kasper DL. Microbial carbohydrate depolymerization by antigen-presenting cells: deamination prior to presentation by the MHCII pathway. Proc. Natl. Acad. Sci. U.S.A. 105: 5183-5188 (2008). *
Duan RS, Jin T, Yang X, Mix E, Adem A, Zhu J. Apolipoprotein E deficiency enhances the antigen-presenting capacity of Schwann cells. Glia 55: 772-776 (2007).
Dubel L, Farges O, Johanet C, Sebagh M, Bismuth H. High incidence of antitissue antibodies in patients experiencing chronic liver allograft rejection. Transplantation 65: 1072-1075 (1998).
Dudziak D, Kamphorst AO, Heidkamp GF, Buchholz VR, Trumpfheller C, Yamazaki S, Cheong C, Liu K, Lee HW, Park CG, Steinman RM, Nussenzweig MC. Differential antigen processing by dendritic cell subsets in vivo. Science 315: 107-111 (2007). *
Dufour FD, Baxter AG, Silveira PA. Interactions between B-lymphocytes and type 1 NKT cells in autoimmune diabetes. J. Immunotoxicol. 5: 249-257 (2008).
Dugan GE, Hewitt EW. Investigation into the dependence of the localisation and function of the human cytomegalovirus protein US6 on the transporter associated with antigen processing. J. Gen. Virol. 90: 2234-2238 (2009). *
Dukkipati VS, Blair HT, Garrick DJ, Murray A. 'Ovar-Mhc' - ovine major histocompatibility complex: structure and gene polymorphisms. Genet. Mol. Res. 5: 581-608 (2006). *
Dukkipati VS, Blair HT, Garrick DJ, Murray A. Ovar-Mhc - Ovine major histocompatibility complex: role in genetic resistance to diseases. N. Z. Vet. J. 54: 153-160 (2006).
Dummer W, Niethammer AG, Baccala R, Lawson BR, Wagner N, Reisfeld RA, Theofilopoulos AN. T cell homeostatic proliferation elicits effective antitumor autoimmunity. J. Clin. Invest. 110: 185-192 (2002). *
Dunn DS, Choy MK, Phipps ME, Kulski JK. The distribution of major histocompatibility complex class I polymorphic Alu insertions and their associations with HLA alleles in a Chinese population from Malaysia. Tissue Antigens 70: 136-143 (2007). *
Dunn DS, Inoko H, Kulski JK. Dimorphic Alu element located between the TFIIH and CDSN genes within the major histocompatibility complex. Electrophoresis 24: 2740-2748 (2003). *
Dunstan SJ, Stephens HA, Blackwell JM, Duc CM, Lanh MN, Dudbridge F, Phuong CX, Luxemburger C, Wain J, Ho VA, Hien TT, Farrar J, Dougan G. Genes of the class II and class III major histocompatibility complex are associated with typhoid fever in Vietnam. J. Infect. Dis. 183: 261-268 (2001). *
Duplan V, Suberbielle E, Napper CE, Joly E, Saoudi A, Gonzalez-Dunia D. Tracking antigen-specific CD8(+) T cells in the rat using MHC class I multimers. J. Immunol. Methods 320: 30-39 (2007). *
Durakovic N, Radojcic V, Skarica M, Bezak KB, Powell JD, Fuchs EJ, Luznik L. Factors governing the activation of adoptively transferred donor T-cells infused after allogeneic bone marrow transplantation in the mouse. Blood 109: 4564-4574 (2007). *
Durand JP, el-Zaatari FA, Krieg AM, Taurog JD. Restriction fragment length polymorphism of T cell receptor alpha and beta chain genes in patients with ankylosing spondylitis. J. Rheumatol. 15: 1115-1158 (1988).
Durinovic-Bello I. Autoimmune diabetes: the role of T cells, MHC molecules and autoantigens. Autoimmunity 27: 159-177 (1998).
Durinovic-Bello I, Wu RP, Gersuk VH, Sanda S, Shilling HG, Nepom GT. Insulin gene VNTR genotype associates with frequency and phenotype of the autoimmune response to proinsulin. Genes Immun. Jan 7 [Epub ahead of print] (2010). *
Durrani K, Papaliodis GN. The genetics of Adamantiades-Behcet's disease. Semin. Ophthalmol. 23: 73-79 (2008).
Dustin ML. T-cell activation through immunological synapses and kinapses. Immunol. Rev. 221: 77-89 (2008). *
Dustin ML. The cellular context of T cell signaling. Immunity 30: 482-492 (2009). *
Duthie A, Doherty DG, Donaldson PT, Scott-Jupp R, Tanner MS, Eddleston AL, Mowat AP. The major histocompatibility complex influences the development of chronic liver disease in male children and young adults with cystic fibrosis. J. Hepatol. 23: 532-537 (1995). *
Duthie MS, Kahn SJ. During acute Trypanosoma cruzi infection highly susceptible mice deficient in natural killer cells are protected by a single alpha-galactosylceramide treatment. Immunology 119: 355-361 (2006). *
Duyar H, Dengjel J, de Graaf KL, Wiesmuller KH, Stevanovic S, Weissert R. Peptide motif for the rat MHC class II molecule RT1.D(a): similarities to the multiple sclerosis-associated HLA-DRB1*1501 molecule. Immunogenetics 57: 69-76 (2005). *
Dyment DA, Cader MZ, Datta A, Broxholme SJ, Cherny SS, Willer CJ, Ramagopalan S, Herrera BM, Orton S, Chao M, Sadovnick AD, Hader M, Hader W, Ebers GC. A first stage genome-wide screen for regions shared identical-by-descent in Hutterite families with multiple sclerosis. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 147B: 467-472 (2008).
Dyment DA, Cader MZ, Herrera BM, Ramagopalan SV, Orton SM, Chao M, Willer CJ, Sadovnick AD, Risch N, Ebers GC. A genome-scan in a single pedigree with a high prevalence of multiple sclerosis. J. Neurol. Neurosurg. Psychiatry 79: 158-162 (2008).
Dyment DA, Herrera BM, Cader MZ, Willer CJ, Lincoln MR, Sadovnick AD, Risch N, Ebers GC. Complex interactions among MHC haplotypes in multiple sclerosis: susceptibility and resistance. Hum. Mol. Genet. 14: 2019-2026 (2005). *
Dzhambazov B, Nandakumar KS, Kihlberg J, Fugger L, Holmdahl R, Vestberg M. Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. J. Immunol. 176: 1525-1533 (2006). *
Eagle RA, Trowsdale J. Promiscuity and the single receptor: NKG2D. Nat. Rev. Immunol. 7: 737-744 (2007). *
Ebert EC, Groh V. Dissection of spontaneous cytotoxicity by human intestinal intraepithelial lymphocytes: MIC on colon cancer triggers NKG2D-mediated lysis through Fas ligand. Immunology 124: 33-41 (2008). *
Ebert EC, Mehta V, Das KM. Activation antigens on colonic T cells in inflammatory bowel disease: effects of IL-10. Clin. Exp. Immunol. 140: 157-165 (2005). *
Ebert LM, Schaerli P, Moser B. Chemokine-mediated control of T cell traffic in lymphoid and peripheral tissues. Mol. Immunol. 42: 799-809 (2005). *
Ebert PJ, Jiang S, Xie J, Li QJ, Davis MM. An endogenous positively selecting peptide enhances mature T cell responses and becomes an autoantigen in the absence of microRNA miR-181a. Nat. Immunol. 10: 1162-1169 (2009). *
Ebihara T, Masuda H, Akazawa T, Shingai M, Kikuta H, Ariga T, Matsumoto M, Seya T. Induction of NKG2D ligands on human dendritic cells by TLR ligand stimulation and RNA virus infection. Int. Immunol. 19: 1145-1155 (2007). *
Ebinuma H, Nakamoto N, Li Y, Price DA, Gostick E, Levine BL, Tobias J, Kwok WW, Chang KM. Identification and in vitro expansion of functional antigen-specific CD25+ FoxP3+ regulatory T cells in hepatitis C virus infection. J. Virol. 82: 5043-5053 (2008). *
Eckhardt A, Harorli T, Limtanyakul J, Hiller KA, Bosl C, Bolay C, Reichl FX, Schmalz G, Schweikl H. Inhibition of cytokine and surface antigen expression in LPS-stimulated murine macrophages by triethylene glycol dimethacrylate. Biomaterials 30: 1665-1674 (2009). *
Egawa T, Littman DR. ThPOK acts late in specification of the helper T cell lineage and suppresses Runx-mediated commitment to the cytotoxic T cell lineage. Nat. Immunol. 9: 1131-1139 (2008). *
Egawa T, Taniuchi I. Antagonistic interplay between ThPOK and Runx in lineage choice of thymocytes. Blood Cells Mol. Dis. 43: 27-29 (2009).
Eggena M, Cohavy O, Parseghian MH, Hamkalo BA, Clemens D, Targan SR, Gordon LK, Braun J. Identification of histone H1 as a cognate antigen of the ulcerative colitis-associated marker antibody pANCA. J. Autoimmun. 14: 83-97 (2000).
Eguchi M, Sekiya Y, Kikuchi Y, Takaya A, Yamamoto T, Matsui H. Expressed Salmonella antigens within macrophages enhance the proliferation of CD4(+) and CD8(+) T lymphocytes by means of bystander dendritic cells. FEMS Immunol. Med. Microbiol. 50: 411-420 (2007). *
Ehses JA, Lacraz G, Giroix MH, Schmidlin F, Coulaud J, Kassis N, Irminger JC, Kergoat M, Portha B, Homo-Delarche F, Donath MY. IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat. Proc. Natl. Acad. Sci. U.S.A. 106: 13998-14003 (2009). *
Eiermann TH, Bettens F, Tiberghien P, Schmitz K, Beurton I, Bresson-Hadni S, Ammann RW, Goldmann SF, Vuitton DA, Gottstein B, Kern P. HLA and alveolar echinococcosis. Tissue Antigens 52: 124-129 (1998).
Eike MC, Becker T, Humphreys K, Olsson M, Lie BA. Conditional analyses on the T1DGC MHC dataset: novel associations with type 1 diabetes around HLA-G and confirmation of HLA-B. Genes Immun. 10: 56-67 (2009). *
Eike MC, Humphreys K, Becker T, Olsson M, Lie BA; Diabetes Genetics Consortium. Three microsatellites from the T1DGC MHC data set show highly significant association with type 1 diabetes, independent of the HLA-DRB1, -DQA1 and -DQB1 genes. Diabetes Obes. Metab. 11 Suppl. 1: 17-24 (2009). *
Eike MC, Olsson M, Undlien DE, Dahl-Jorgensen K, Joner G, Ronningen KS, Thorsby E, Lie BA. Genetic variants of the HLA-A, HLA-B and AIF1 loci show independent associations with type 1 diabetes in Norwegian families. Genes Immun. 10: 141-150 (2009). *
Einstein MH, Leanza S, Chiu LG, Schlecht NF, Goldberg GL, Steinberg BM, Burk RD. Genetic variants in TAP are associated with high-grade cervical neoplasia. Clin. Cancer Res. 15: 1019-1023 (2009). *
Eisen HN. Specificity and degeneracy in antigen recognition: yin and yang in the immune system. Annu. Rev. Immunol. 19: 1-21 (2001). *
Eisenlohr LC, Huang L, Golovina TN. Rethinking peptide supply to MHC class I molecules. Nat. Rev. Immunol. 7: 403-410 (2007). *
Eisfeld AJ, Yee MB, Erazo A, Abendroth A, Kinchington PR. Downregulation of class I major histocompatibility complex surface expression by varicella-zoster virus involves open reading frame 66 protein kinase dependent and independent mechanisms. J. Virol. 81: 9034-9049 (2007). *
Eizaguirre C, Yeates SE, Lenz TL, Kalbe M, Milinski M. MHC-based mate choice combines good genes and maintenance of MHC polymorphism. Mol. Ecol. 18: 3316-3329 (2009).
El Haj M, Ya'acov AB, Lalazar G, Ilan Y. Potential role of NKT regulatory cell ligands for the treatment of immune mediated colitis. World J. Gastroenterol. 13: 5799-5804 (2007). *
El-Chennawi FA, Auf FA, Metwally SS, Mosaad YM, El-Wahab MA, Tawhid ZE. HLA-class II alleles in Egyptian patients with hepatocellular carcinoma. Immunol. Invest. 37: 661-674 (2008). *
El-Gabalawy HS, Goldbach-Mansky R, Smith D 2nd, Arayssi T, Bale S, Gulko P, Yarboro C, Wilder RL, Klippel JH, Schumacher HR Jr. Association of HLA alleles and clinical features in patients with synovitis of recent onset. Arthritis Rheum. 42: 1696-1705 (1999). *
Elagin RB, Balijepalli S, Diacovo MJ, Baekkeskov S, Jaume JC. Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice. J. Autoimmun. 33: 50-57 (2009).
Elahi MM, Asotra K, Matata BM, Mastana SS. Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease. Biochim. Biophys. Acta 1792: 163-172 (2009).
Elahi MM, Asotra K, Matata BM, Mastana SS. Tumour necrosis factor alpha-308 gene locus promoter polymorphism: an analysis of association with health and disease. Biochim. Biophys. Acta Jan 26 [Epub ahead of print] (2009). *
Elamin NE, Elbashir MI, Elkhidir IM, Elghazali G, Blasczyk R, Horn PA. Identification of four new HLA-Cw alleles in the Sudanese population. Tissue Antigens 69: 270-272 (2007). *
Elder JT. PSORS1: linking genetics and immunology. J. Invest. Dermatol. 126: 1205-1206 (2006). *
Elder JT. Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis. Genes Immun. 10: 201-209 (2009). *
Elder JT, Bruce AT, Gudjonsson JE, Johnston A, Stuart PE, Tejasvi T, Voorhees JJ, Abecasis GR, Nair RP. Molecular dissection of psoriasis: integrating genetics and biology. J. Invest. Dermatol. Oct 8 [Epub ahead of print] (2009). *
Elder JT, Nair RP, Henseler T, Jenisch S, Stuart P, Chia N, Christophers E, Voorhees JJ. The genetics of psoriasis 2001: the odyssey continues. Arch. Dermatol. 137: 1447-1454 (2001). *
Eldor R, Cohen IR, Raz I. Innovative immune-based therapeutic approaches for the treatment of type 1 diabetes mellitus. Int. Rev. Immunol. 24: 327-339 (2005).
Eleftheriadis T, Voyatzi S, Antoniadi G, Kartsios C, Liakopoulos V, Paraskevopoulos P, Galaktidou G. Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells. Cell. Immunol. 240: 62-67 (2006). *
Elgueta R, Tobar JA, Shoji KF, De Calisto J, Kalergis AM, Bono MR, Rosemblatt M, Saez JC. Gap junctions at the dendritic cell-T cell interface are key elements for antigen-dependent T cell activation. J. Immunol. 183: 277-284 (2009).
Elinav E, Waks T, Eshhar Z. Redirection of regulatory T cells with predetermined specificity for the treatment of experimental colitis in mice. Gastroenterology 134: 2014-2024 (2008). *
Ellestad KK, Tsutsui S, Noorbakhsh F, Warren KG, Yong VW, Pittman QJ, Power C. Early life exposure to lipopolysaccharide suppresses experimental autoimmune encephalomyelitis by promoting tolerogenic dendritic cells and regulatory T cells. J. Immunol. 183: 298-309 (2009).
Ellis SA, Bontrop RE, Antczak DF, Ballingall K, Davies CJ, Kaufman J, Kennedy LJ, Robinson J, Smith DM, Stear MJ, Stet RJ, Waller MJ, Walter L, Marsh SG. ISAG/IUIS-VIC Comparative MHC Nomenclature Committee report, 2005. Immunogenetics 57: 953-958 (2006). *
Elson CO, Kagnoff MF, Fiocchi C, Befus AD, Targan S. Intestinal immunity and inflammation: recent progress. Gastroenterology 91: 746-768 (1986).
Ely LK, Beddoe T, Clements CS, Matthews JM, Purcell AW, Kjer-Nielsen L, McCluskey J, Rossjohn J. Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction. Proc. Natl. Acad. Sci. U.S.A. 103: 6641-6646 (2006). *
Ely LK, Burrows SR, Purcell AW, Rossjohn J, McCluskey J. T-cells behaving badly: structural insights into alloreactivity and autoimmunity. Curr. Opin. Immunol. 20: 575-580 (2008). *
Ely LK, Kjer-Nielsen L, McCluskey J, Rossjohn J. Structural studies on the alphabeta T-cell receptor. IUBMB Life 57: 575-582 (2005). *
Endert PV. Role of tripeptidyl peptidase II in MHC class I antigen processing - the end of controversies? Eur. J. Immunol. 38: 609-613 (2008). *
Enee E, Martinuzzi E, Blancou P, Bach JM, Mallone R, van Endert P. Equivalent specificity of peripheral blood and islet-infiltrating CD8+ T lymphocytes in spontaneously diabetic HLA-A2 transgenic NOD mice. J. Immunol. 180: 5430-5438 (2008). *
Engelhardt B. The blood-central nervous system barriers actively control immune cell entry into the central nervous system. Curr. Pharm. Des. 14: 1555-1565 (2008).
English L, Chemali M, Duron J, Rondeau C, Laplante A, Gingras D, Alexander D, Leib D, Norbury C, Lippe R, Desjardins M. Autophagy enhances the presentation of endogenous viral antigens on MHC class I molecules during HSV-1 infection. Nat. Immunol. 10: 480-487 (2009). *
Eran E, Nitzan A, Tova W, Eshhar Z. Amelioration of colitis by genetically engineered murine regulatory T cells redirected by antigen-specific chimeric receptor. Gastroenterology 136: 1721-1731 (2009). *
Eren E, Yates J, Cwynarski K, Preston S, Dong R, Germain C, Lechler R, Huby R, Ritter M, Lombardi G. Location of major histocompatibility complex class II molecules in rafts on dendritic cells enhances the efficiency of T-cell activation and proliferation. Scand. J. Immunol. 63: 7-16 (2006). *
Eriksen KW, Sondergaard H, Woetmann A, Krejsgaard T, Skak K, Geisler C, Wasik MA, Odum N. The combination of IL-21 and IFN-alpha boosts STAT3 activation, cytotoxicity and experimental tumor therapy. Mol. Immunol. 46: 812-820 (2009). *
Eriksson AU, Singh RR. Cutting edge: migration of Langerhans dendritic cells is impaired in autoimmune dermatitis. J. Immunol. 181: 7468-7472 (2008). *
Erlich HA. HLA class II sequences and genetic susceptibility to insulin dependent diabetes mellitus. Baillieres Clin. Endocrinol. Metab. 5: 395-411 (1991).
Erlich HA. HLA class II polymorphism and genetic susceptibility to insulin-dependent diabetes mellitus. Curr. Top. Microbiol. Immunol. 164: 41-55 (1990).
Erlich HA, Lohman K, Mack SJ, Valdes AM, Julier C, Mirel D, Noble JA, Morahan GE, Rich SS; for the Type I Diabetes Genetics Consortium. Association analysis of SNPs in the IL4R locus with type I diabetes. Genes Immun. 10: S33-S41 (2009).
Esen N, Kielian T. Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs). J. Neuroinflammation 4: 10 (2007). *
Eshima K, Suzuki H, Shinohara N. Cross-positive selection of thymocytes expressing a single TCR by multiple major histocompatibility complex molecules of both classes: implications for CD4+ versus CD8+ lineage commitment. J. Immunol. 176: 1628-1636 (2006). *
Ettinger RA, Liu AW, Nepom GT, Kwok WW. Beta 57-Asp plays an essential role in the unique SDS stability of HLA-DQA1*0102/DQB1*0602 alpha beta protein dimer, the class II MHC allele associated with protection from insulin-dependent diabetes mellitus. J. Immunol. 165: 3232-3238 (2000). *
Evdokimova VN, Liu Y, Potter DM, Butterfield LH. AFP-specific CD4+ helper T-cell responses in healthy donors and HCC patients. J. Immunother. 30: 425-437 (2007).
Evoli A, Batocchi AP, Zelano G, Uncini A, Palmisani MT, Tonali P. Familial autoimmune myasthenia gravis: report of four families. J. Neurol. Neurosurg. Psychiatry 58: 729-731 (1995).
Ewer K, Cockle P, Gordon S, Mansoor H, Govaerts M, Walravens K, Marche S, Hewinson G, Vordermeier M. Antigen mining with iterative genome screens identifies novel diagnostics for the Mycobacterium tuberculosis complex. Clin. Vaccine Immunol. 13: 90-97 (2006). *
Ewing C, Bernard CC. Insights into the aetiology and pathogenesis of multiple sclerosis. Immunol. Cell. Biol. 76: 47-54 (1998). *
Ewing C, Ebringer R, Tribbick G, Geysen HM. Antibody activity in ankylosing spondylitis sera to two sites on HLA B27.1 at the MHC groove region (within sequence 65-85), and to a Klebsiella pneumoniae nitrogenase reductase peptide (within sequence 181-199). J. Exp. Med. 171: 1635-1647 (1990). *
Eyre S, Bowes J, Spreckley K, Potter C, Ring S, Strachan D, Worthington J, Barton A. Investigation of the MHC2TA gene, associated with rheumatoid arthritis in a Swedish population, in a UK rheumatoid arthritis cohort. Arthritis Rheum. 54: 3417-3422 (2006). *
Fabricius D, Neubauer M, Mandel B, Schutz C, Viardot A, Vollmer A, Jahrsdorfer B, Debatin KM. Prostaglandin E2 inhibits IFN-alpha secretion and Th1 costimulation by human plasmacytoid dendritic cells via E-prostanoid (EP) 2 and EP4 receptor rngagement. J. Immunol. 184: 677-684 (2010).
Fahlen-Yrlid L, Gustafsson T, Westlund J, Holmberg A, Strombeck A, Blomquist M, Macpherson GG, Holmgren J, Yrlid U. CD11chigh dendritic cells are essential for activation of CD4+ T cells and generation of specific antibodies following mucosal immunization. J. Immunol. 183: 5032-5041 (2009).
Fahmy TM, Schneck JP, Saltzman WM. A nanoscopic multivalent antigen-presenting carrier for sensitive detection and drug delivery to T cells. Nanomedicine 3: 75-85 (2007).
Fain PR, Babu SR, Bennett DC, Spritz RA. HLA class II haplotype DRB1*04-DQB1*0301 contributes to risk of familial generalized vitiligo and early disease onset. Pigment Cell Res. 19: 51-57 (2006). *
Fajardo-Dolci G, Solorio-Abreu J, Romero-Alvarez JC, Zavaleta-Villa B, Cerezo-Camacho O, Jimenez-Lucio R, Olivo-Diaz A. DQA1 and DQB1 association and nasal polyposis. Otolaryngol. Head Neck Surg. 135: 243-247 (2006).
Fallang LE, Bergseng E, Hotta K, Berg-Larsen A, Kim CY, Sollid LM. Differences in the risk of celiac disease associated with HLA-DQ2.5 or HLA-DQ2.2 are related to sustained gluten antigen presentation. Nat. Immunol. 10: 1096-1101 (2009). *
Falorni A. Immunologic and genetic aspects of latent autoimmune diabetes in the adult. Minerva Endocrinol. 28: 297-312 (2003).
Falta MT, Fontenot AP, Rosloniec EF, Crawford F, Roark CL, Bill J, Marrack P, Kappler J, Kotzin BL. Class II major histocompatibility complex-peptide tetramer staining in relation to functional avidity and T cell receptor diversity in the mouse CD4+ T cell response to a rheumatoid arthritis-associated antigen. Arthritis Rheum. 52: 1885-1896 (2005). *
Fang C, Ballet C, Dugast AS, Godard A, Moreau A, Usal C, Smit H, Vanhove B, Brouard S, Harb J, Soulillou JP. Autoimmune responses against renal tissue proteins in long-term surviving allograft recipients. Transpl. Int. 22: 1091-1099 (2009). *
Fanning SL, Appel MY, Berger SA, Korngold R, Friedman TM. The immunological impact of genetic drift in the B10.BR congenic inbred mouse strain. J. Immunol. 183: 4261-4272 (2009).
Farid NR, Thompson C. HLA and autoimmune endocrine disease 1985. Mol. Biol. Med. 3: 85-97 (1986).
Farjadian S, Kiyanimanesh N, Abbaszadegan A, Lotfazar M. HLA class I gene polymorphism in Iranian patients with Papillon-Lefevre syndrome. Iran. J. Immunol. 4: 241-245 (2007).
Farmer MA, Sundberg JP, Bristol IJ, Churchill GA, Li R, Elson CO, Leiter EH. A major quantitative trait locus on chromosome 3 controls colitis severity in IL-10-deficient mice. Proc. Natl. Acad. Sci. U.S.A. 98: 13820-13825 (2001). *
Farras R, Bossis G, Andermarcher E, Jariel-Encontre I, Piechaczyk M. Mechanisms of delivery of ubiquitylated proteins to the proteasome: new target for anti-cancer therapy? Crit. Rev. Oncol. Hematol. 54: 31-51 (2005).
Farrell H, Degli-Esposti M, Densley E, Cretney E, Smyth M, Davis-Poynter N. Cytomegalovirus MHC class I homologues and natural killer cells: an overview. Microbes Infect. 2: 521-532 (2000). *
Fathman CG, Lineberry NB. Molecular mechanisms of CD4(+) T-cell anergy. Nat. Rev. Immunol. 7: 599-609 (2007). *
Faure-Andre G, Vargas P, Yuseff MI, Heuze M, Diaz J, Lankar D, Steri V, Manry J, Hugues S, Vascotto F, Boulanger J, Raposo G, Bono MR, Rosemblatt M, Piel M, Lennon-Dumenil AM. Regulation of dendritic cell migration by CD74, the MHC class II-associated invariant chain. Science 322: 1705-1710 (2008). *
Fauriat C, Ivarsson MA, Ljunggren HG, Malmberg KJ, Michaelsson J. Education of human natural killer cells by activating killer cell immunoglobulin-like receptors. Blood Nov 10 [Epub ahead of print] (2009). *
Fauroux B, Clement A. Paediatric sarcoidosis. Paediatr. Respir. Rev. 6: 128-133 (2005).
Faustman DL, Davis M. The primacy of CD8 T lymphocytes in type 1 diabetes and implications for therapies. J. Mol. Med. 87: 1173-1178 (2009). *
Fava G, Glaser S, Francis H, Alpini G. The immunophysiology of biliary epithelium. Semin. Liver Dis. 25: 251-264 (2005).
Favier B, Lemaoult J, Rouas-Freiss N, Moreau P, Menier C, Carosella ED. Research on HLA-G: an update. Tissue Antigens 69: 207-211 (2007). *
Fazilleau N, Eisenbraun MD, Malherbe L, Ebright JN, Pogue-Caley RR, McHeyzer-Williams LJ, McHeyzer-Williams MG. Lymphoid reservoirs of antigen-specific memory T helper cells. Nat. Immunol. 8: 753-761 (2007). *
Fazilleau N, McHeyzer-Williams LJ, Rosen H, McHeyzer-Williams MG. The function of follicular helper T cells is regulated by the strength of T cell antigen receptor binding. Nat. Immunol. 10: 375-384 (2009). *
Fdez-Morera JL, Rodrigo L, Lopez-Vazquez A, Rodero SR, Martinez-Borra J, Nino P, Gonzalez S, Lopez-Larrea C. MHC class I chain-related gene A transmembrane polymorphism modulates the extension of ulcerative colitis. Hum. Immunol. 64: 816-822 (2003).
Fdez-Morera JL, Tunon A, Rodriguez-Rodero S, Rodrigo L, Martinez-Borra J, Gonzalez S, Lopez-Vazquez A, Lahoz CH, Lopez-Larrea C. Clinical behavior of multiple sclerosis is modulated by the MHC class I-chain-related gene A. Tissue Antigens 67: 409-414 (2006). *
Fedyk ER, Phipps RP. Prostaglandin E2 receptors of the EP2 and EP4 subtypes regulate activation and differentiation of mouse B lymphocytes to IgE-secreting cells. Proc. Natl. Acad. Sci. U.S.A. 93: 10978-10983 (1996). *
Feghali-Bostwick C, Medsger TA Jr, Wright TM. Analysis of systemic sclerosis in twins reveals low concordance for disease and high concordance for the presence of antinuclear antibodies. Arthritis Rheum. 48: 1956-1963 (2003). *
Feillet H, Bach JF. Increased incidence of inflammatory bowel disease: the price of the decline of infectious burden? Curr. Opin. Gastroenterol. 20: 560-564 (2004).
Feld J, Heathcote E. Epidemiology of autoimmune liver disease. J. Gastroenterol. Hepatol. 18: 1118-1128 (2003). *
Felix NJ, Allen PM. Specificity of T-cell alloreactivity. Nat. Rev. Immunol. 7: 942-953 (2007). *
Feng BJ, Sun LD, Soltani-Arabshahi R, Bowcock AM, Nair RP, Stuart P, Elder JT, Schrodi SJ, Begovich AB, Abecasis GR, Zhang XJ, Callis-Duffin KP, Krueger GG, Goldgar DE. Multiple loci within the major histocompatibility complex confer risk of psoriasis. PLoS Genet. 5: e1000606 (2009). *
Feng D, Bond CJ, Ely LK, Maynard J, Garcia KC. Structural evidence for a germline-encoded T cell receptor-major histocompatibility complex interaction 'codon'. Nat. Immunol. 8: 975-983 (2007). *
Feng YL, Liu S, Shao LL, Shan BE. The antitumor effect and immunomechanism of IL-23 in mouse mammary cancer. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 24: 853-856 (2008).
Ferguson CA. Disease models of autoimmunity. Trends Immunol. 26: 557-558 (2005). *
Ferguson LR, Shelling AN, Browning BL, Huebner C, Petermann I. Genes, diet and inflammatory bowel disease. Mutat. Res. 622: 70-83 (2007).
Ferguson TA, Griffith TS. The role of Fas ligand and TNF-related apoptosis-inducing ligand (TRAIL) in the ocular immune response. Chem. Immunol. Allergy 92: 140-154 (2007).
Fernandez Arquero M, Lopez Nava G, De la Concha EG, Figueredo MA, Santa Cruz S, Dumitru CG, Diaz Rubio M, Garcia Paredes J. HLA-DR2 gene and Spanish patients with ulcerative colitis. Rev. Esp. Enferm. Dig. 90: 243-249 (1998).
Fernandez L, Fernandez-Arquero M, Gual L, Lazaro F, Maluenda C, Polanco I, Figueredo MA, Gomez de la Concha E. Triplet repeat polymorphism in the transmembrane region of the MICA gene in celiac disease. Tissue Antigens 59: 219-222 (2002). *
Fernandez L, Nunez C, Mendoza JL, Urcelay E, Fernandez-Arquero M, Taxonera C, Diaz-Rubio M, de la Concha EG, Martinez A. A recombined haplotype in the major histocompatibility region contains a cluster of genes conferring high susceptibility to ulcerative colitis in the Spanish population. Inflamm. Bowel Dis. 11: 785-791 (2005). *
Fernandez MM, Bhattacharya S, De Marzi MC, Brown PH, Kerzic M, Schuck P, Mariuzza RA, Malchiodi EL. Superantigen natural affinity maturation revealed by the crystal structure of staphylococcal enterotoxin G and its binding to T-cell receptor Vbeta8.2. Proteins 68: 389-402 (2007). *
Fernandez O, R-Antiguedad A, Pinto-Medel MJ, Mendibe MM, Acosta N, Oliver B, Guerrero M, Papais-Alvarenga M, Fernandez-Sanchez V, Leyva L. HLA class II alleles in patients with multiple sclerosis in the Biscay province (Basque Country, Spain). J. Neurol. Jul 8 [Epub ahead of print] (2009).
Fernandez-Arquero M, Figueredo MA, Maluenda C, de la Concha EG. HLA-linked genes acting as additive susceptibility factors in celiac disease. Hum. Immunol. 42: 295-300 (1995).
Fernandez-Arquero M, Lopez-Nava G, Garcia Paredes J, Martinez A, De la Concha EG, Figueredo MA, Conejero L, Vigil P, Diaz Rubio M. Pancolitis and genetic markers in the Spanish population. Rev. Esp. Enferm. Dig. 91: 269-276 (1999).
Fernandez-Morera JL, Rodriguez-Rodero S, Lahoz C, Tunon A, Astudillo A, Garcia-Suarez O, Martinez-Borra J, Lopez-Vazquez A, Rodrigo L, Gonzalez S, Lopez-Larrea C. Soluble MHC class I chain-related protein B serum levels correlate with disease activity in relapsing-remitting multiple sclerosis. Hum. Immunol. 69: 235-240 (2008).
Fernandez-Morera JL, Rodriguez-Rodero S, Tunon A, Martinez-Borra J, Vidal-Castineira JR, Lopez-Vazquez A, Rodrigo L, Rodrigo P, Gonz�lez S, Lahoz CH, Lopez-Larrea C. Genetic influence of the nonclassical major histocompatibility complex class I molecule MICB in multiple sclerosis susceptibility. Tissue Antigens 72: 54-59 (2008). *
Fernandez-Vina M, Ramirez LC, Raskin P, Stastny P. Genes for insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) of African-Americans. Tissue Antigens 41: 57-64 (1993).
Fernando MM, Stevens CR, Sabeti PC, Walsh EC, McWhinnie AJ, Shah A, Green T, Rioux JD, Vyse TJ. Identification of two independent risk factors for lupus within the MHC in United Kingdom families. PLoS Genet. 3: e192 (2007). *
Fernando MM, Stevens CR, Walsh EC, De Jager PL, Goyette P, Plenge RM, Vyse TJ, Rioux JD. Defining the role of the MHC in autoimmunity: a review and pooled analysis. PLoS Genet. 4: e1000024 (2008). *
Ferrante A, Gorski J. Cutting edge: HLA-DM-mediated peptide exchange functions normally on MHC class II-peptide complexes that have been weakened by elimination of a conserved hydrogen bond. J. Immunol. Dec 28 [Epub ahead of print] (2009).
Ferrari-Lacraz S, Zheng XX, Fueyo AS, Maslinski W, Moll T, Strom TB. CD8+ T cells resistant to costimulatory blockade are controlled by an antagonist interleukin-15/Fc protein. Transplantation 82: 1510-1517 (2006).
Ferreira C, Singh Y, Furmanski AL, Wong FS, Garden OA, Dyson J. Non-obese diabetic mice select a low-diversity repertoire of natural regulatory T cells. Proc. Natl. Acad. Sci. U.S.A. 106: 8320-8325 (2009). *
Ferreira MA, Mangino M, Brumme CJ, Zhao ZZ, Medland SE, Wright MJ, Nyholt DR, Gordon S, Campbell M, McEvoy BP, Henders A, Evans DM, Lanchbury JS, Pereyra F; International HIV Controllers Study. Quantitative trait loci for CD4:CD8 lymphocyte ratio are associated with risk of type 1 diabetes and HIV-1 immune control. Am. J. Hum. Genet. Dec 30 [Epub ahead of print] (2009). *
Feuerer M, Jiang W, Holler PD, Satpathy A, Campbell C, Bogue M, Mathis D, Benoist C. Enhanced thymic selection of FoxP3+ regulatory T cells in the NOD mouse model of autoimmune diabetes. Proc. Natl. Acad. Sci. U.S.A. 104: 18181-18186 (2007). *
Field SF, Nejentsev S, Walker NM, Howson JM, Godfrey LM, Jolley JD, Hardy MP, Todd JA. Sequencing-based genotyping and association analysis of the MICA and MICB genes in type 1 diabetes. Diabetes 57: 1753-1756 (2008). *
Figueiredo C, Horn PA, Blasczyk R, Seltsam A. Regulating MHC expression for cellular therapeutics. Transfusion 47: 18-27 (2007).
Figueredo J, Limberis M, Wilson JM. Prediction of cellular immune responses against CFTR in cystic fibrosis patients after gene therapy. Am. J. Respir. Cell. Mol. Biol. 36: 529-533 (2007). *
Figueroa-Vega N, Galindo-Rodriguez G, Bajana S, Portales-Perez D, Abud-Mendoza C, Sanchez-Torres C, Gonzalez-Amaro R. Phenotypic analysis of IL-10-treated, monocyte-derived dendritic cells in patients with systemic lupus erythematosus. Scand. J. Immunol. 64: 668-676 (2006). *
Fikri Y, Nyabenda J, Content J, Huygen K. Cloning, sequencing, and cell surface expression pattern of bovine immunoreceptor NKG2D and adaptor molecules DAP10 and DAP12. Immunogenetics 59: 653-659 (2007). *
Filosto M, Tonin P, Vattemi G, Bertolasi L, Simonati A, Rizzuto N, Tomelleri G. The role of muscle biopsy in investigating isolated muscle pain. Neurology 68: 181-186 (2007).
Finnish-German APECED Consortium. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains. The Finnish-German APECED Consortium. Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy. Nat. Genet. 17: 399-403 (1997). *
Fionda C, Soriani A, Malgarini G, Iannitto ML, Santoni A, Cippitelli M. Heat shock protein-90 inhibitors increase MHC class I-related chain A and B ligand expression on multiple myeloma cells and their ability to trigger NK cell degranulation. J. Immunol. 183: 4385-4394 (2009).
Fiorillo MT, Ruckert C, Hulsmeyer M, Sorrentino R, Saenger W, Ziegler A, Uchanska-Ziegler B. Allele-dependent similarity between viral and self-peptide presentation by HLA-B27 subtypes. J. Biol. Chem. 280: 2962-2971 (2005). *
Fischer GF, Mayr WR. Molecular genetics of the HLA complex. Wien. Klin. Wochenschr. 113: 814-824 (2001).
Fissolo N, Haag S, de Graaf KL, Drews O, Stevanovic S, Rammensee HG, Weissert R. Naturally presented peptides on MHC I and II molecules eluted from central nervous system of multiple sclerosis patients. Mol. Cell. Proteomics 8: 2090-2101 (2009). *
Fissolo N, Kraus M, Reich M, Ayturan M, Overkleeft H, Driessen C, Weissert R. Dual inhibition of proteasomal and lysosomal proteolysis ameliorates autoimmune central nervous system inflammation. Eur. J. Immunol. 38: 2401-2411 (2008). *
Flad T, Mueller L, Dihazi H, Grigorova V, Bogumil R, Beck A, Thedieck C, Mueller GA, Kalbacher H, Mueller CA. T cell epitope definition by differential mass spectrometry: identification of a novel, immunogenic HLA-B8 ligand directly from renal cancer tissue. Proteomics 6: 364-374 (2006). *
Fleischer B. Superantigens produced by infectious pathogens: molecular mechanism of action and biological significance. Int. J. Clin. Lab. Res. 24: 193-197 (1994).
Flesch IE, Woo WP, Wang Y, Panchanathan V, Wong YC, La Gruta NL, Cukalac T, Tscharke DC. Altered CD8+ T cell immunodominance after vaccinia virus infection and the naive repertoire in inbred and F1 mice. J. Immunol. 184: 45-55 (2010).
Fletcher AL, Lowen TE, Sakkal S, Reiseger JJ, Hammett MV, Seach N, Scott HS, Boyd RL, Chidgey AP. Ablation and regeneration of tolerance-inducing medullary thymic epithelial cells after cyclosporine, cyclophosphamide, and dexamethasone treatment. J. Immunol. 183: 823-831 (2009).
Fletcher AL, Seach N, Reiseger JJ, Lowen TE, Hammett MV, Scott HS, Boyd RL. Reduced thymic Aire expression and abnormal NF-kappaB2 signaling in a model of systemic autoimmunity. J. Immunol. 182: 2690-2699 (2009).
Flierman R, Witteveen HJ, van der Voort EI, Huizinga TW, de Vries RR, Fibbe WE, Toes RE, van Laar JM. Control of systemic B cell-mediated autoimmune disease by nonmyeloablative conditioning and MHC-mismatched allogeneic bone marrow transplantation. Blood 105: 2991-2994 (2005). *
Flores-Villanueva PO, Hendel H, Caillat-Zucman S, Rappaport J, Burgos-Tiburcio A, Bertin-Maghit S, Ruiz-Morales JA, Teran ME, Rodriguez-Tafur J, Zagury JF. Associations of MHC ancestral haplotypes with resistance/susceptibility to AIDS disease development. J. Immunol. 170: 1925-1929 (2003). *
Flori L, Delahaye NF, Iraqi FA, Hernandez-Valladares M, Fumoux F, Rihet P. TNF as a malaria candidate gene: polymorphism-screening and family-based association analysis of mild malaria attack and parasitemia in Burkina Faso. Genes Immun. 6: 472-480 (2005). *
Flutter B, Gao B. MHC class I antigen presentation - recently trimmed and well presented. Cell. Mol. Immunol. 1: 22-30 (2004). *
Foell J, Hewes B, Mittler RS. T cell costimulatory and inhibitory receptors as therapeutic targets for inducing anti-tumor immunity. Curr. Cancer Drug Targets 7: 55-70 (2007).
Foell J, Mittler RS. Costimulatory molecules as immunotherapeutic targets in systemic lupus erythematosus. Springer Semin. Immunopathol. 28: 153-162 (2006). *
Folwaczny C, Zahn R, Brunnler G, Albert E, Koenig A, Noehl N, Loeschke K, Fricke H. Lack of association between HLA-DRB1 alleles of the major histocompatibility complex and p-ANCA status or clinical characteristics in patients with ulcerative colitis. Z. Gastroenterol. 37: 133-140 (1999).
Fong L, Engleman EG. Dendritic cells in cancer immunotherapy. Annu. Rev. Immunol. 18: 245-273 (2000). *
Fontaine B, Semana G, Clerget-Darpoux F; au nom de REFGENSEP (Reseau francais d'etude genetique de la SEP). What's new in multiple sclerosis genetics? Rev. Neurol. (Paris) 163: 677-681 (2007).
Fontenot AP, Torres M, Marshall WH, Newman LS, Kotzin BL. Beryllium presentation to CD4+ T cells underlies disease-susceptibility HLA-DP alleles in chronic beryllium disease. Proc. Natl. Acad. Sci. U.S.A. 97: 12717-12722 (2000). *
Fontenot JD, Rasmussen JP, Williams LM, Dooley JL, Farr AG, Rudensky AY. Regulatory T cell lineage specification by the forkhead transcription factor Foxp3. Immunity 22: 329-341 (2005). *
Fooksman DR, Vardhana S, Vasiliver-Shamis G, Liese J, Blair D, Waite J, Sacristan C, Victora G, Zanin-Zhorov A, Dustin ML. Functional anatomy of T cell activation and synapse formation. Annu. Rev. Immunol. Nov 10 [Epub ahead of print] (2009). *
Forcione DG, Sands B, Isselbacher KJ, Rustgi A, Podolsky DK, Pillai S. An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3*0301 allele. Proc. Natl. Acad. Sci. U.S.A. 93: 5094-5098 (1996). *
Ford McIntyre MS, Young KJ, Gao J, Joe B, Zhang L. Cutting edge: in vivo trogocytosis as a mechanism of double negative regulatory T cell-mediated antigen-specific suppression. J. Immunol. 181: 2271-2275 (2008). *
Ford MS, Chen W, Wong S, Li C, Vanama R, Elford AR, Asa SL, Ohashi PS, Zhang L. Peptide-activated double-negative T cells can prevent autoimmune type-1 diabetes development. Eur. J. Immunol. 37: 2234-2241 (2007).
Forman D, Tian C, Iacomini J. Induction of donor-specific tolerance in sublethally irradiated recipients by gene therapy. Mol. Ther. 12: 353-359 (2005).
Forsthuber TG, Shive CL, Wienhold W, de Graaf K, Spack EG, Sublett R, Melms A, Kort J, Racke MK, Weissert R. T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells. J. Immunol. 167: 7119-7125 (2001). *
Forte P, Baumann BC, Schneider MK, Seebach JD. HLA-Cw4 expression on porcine endothelial cells reduces cytotoxicity and adhesion mediated by CD158a human NK cells. Xenotransplantation 16: 19-26 (2009).
Fortes MD, Machado IV, Gil G, Fernandez-Mestre M, Dagher L, Leon RV, Bianco NE, Tassinari P. Genetic contribution of major histocompatibility complex class II region to type 1 autoimmune hepatitis susceptibility in Venezuela. Liver Int. 27: 1409-1416 (2007). *
Fortin CF, McDonald PP, Lesur O, Fulop T. Aging and neutrophils: there is still much to do. Rejuvenation Res. 11: 873-882 (2008).
Foulis AK. Pancreatic pathology in type 1 diabetes in human. Novartis Found. Symp. 292: 2-13 (2008).
Fourneau JM, Bach JM, van Endert PM, Bach JF. The elusive case for a role of mimicry in autoimmune diseases. Mol. Immunol. 40: 1095-1102 (2004). *
Frahm N, Yusim K, Suscovich TJ, Adams S, Sidney J, Hraber P, Hewitt HS, Linde CH, Kavanagh DG, Woodberry T, Henry LM, Faircloth K, Listgarten J, Kadie C, Jojic N, Sango K, Brown NV, Pae E, Zaman MT, Bihl F, Khatri A, John M, Mallal S, Marincola FM, et al. Extensive HLA class I allele promiscuity among viral CTL epitopes. Eur. J. Immunol. 37: 2419-2433 (2007). *
Fraile A, Collado MD, Mataran L, Martin J, Nieto A. TAP1 and TAP2 polymorphism in Spanish patients with ankylosing spondylitis. Exp. Clin. Immunogenet. 17: 199-204 (2000).
Franciotta D, Cuccia M, Dondi E, Piccolo G, Cosi V. Polymorphic markers in MHC class II/III region: a study on Italian patients with myasthenia gravis. J. Neurol. Sci. 190: 11-16 (2001). *
Fraser CK, Blake SJ, Diener KR, Lyons AB, Brown MP, Hughes TP, Hayball JD. Dasatinib inhibits recombinant viral antigen-specific murine CD4(+) and CD8(+) T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Exp. Hematol. 37: 256-265 (2009).
Fraser J, Arcus V, Kong P, Baker E, Proft T. Superantigens - powerful modifiers of the immune system. Mol. Med. Today 6: 125-132 (2000).
Fraser JD, Proft T. The bacterial superantigen and superantigen-like proteins. Immunol. Rev. 225: 226-243 (2008). *
Frei R, Steinle J, Birchler T, Loeliger S, Roduit C, Steinhoff D, Seibl R, Buchner K, Seger R, Reith W, Lauener RP. MHC class II molecules enhance Toll-like receptor mediated innate immune responses. PLoS One 5: e8808 (2010). *
Freria CM, Zanon RG, Santos LM, Oliveira AL. Major histocompatability complex class I expression and glial reaction influence spinal motoneuron synaptic plasticity during the course of experimental autoimmune encephalomyelitis. J. Comp. Neurol. 518: 990-1007 (2010).
Freyschmidt-Paul P, McElwee KJ, Hoffmann R, Sundberg JP, Vitacolonna M, Kissling S, Zoller M. Interferon-gamma-deficient mice are resistant to the development of alopecia areata. Br. J. Dermatol. 155: 515-521 (2006). *
Friday RP, Trucco M, Pietropaolo M. Genetics of type 1 diabetes mellitus. Diabetes Nutr. Metab. 12: 3-26 (1999).
Friese MA, Fugger L. Pathogenic CD8(+) T cells in multiple sclerosis. Ann. Neurol. 66: 132-141 (2009).
Friese MA, Fugger L. Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain 128: 1747-1763 (2005). *
Friese MA, Jakobsen KB, Friis L, Etzensperger R, Craner MJ, McMahon RM, Jensen LT, Huygelen V, Jones EY, Bell JI, Fugger L. Opposing effects of HLA class I molecules in tuning autoreactive CD8(+) T cells in multiple sclerosis. Nat. Med. 14: 1227-1235 (2008). *
Friese MA, Jones EY, Fugger L. MHC II molecules in inflammatory diseases: interplay of qualities and quantities. Trends Immunol. 26: 559-561 (2005). *
Frigoul A, Lefranc MP. MICA: standardized IMGT allele nomenclature, polymorphisms and diseases. Recent Res. Devel. Human Genet. 3: 95-145 (2005). *
Fronek Z, Timmerman LA, Alper CA, Hahn BH, Kalunian K, Peterlin BM, McDevitt HO. Major histocompatibility complex associations with systemic lupus erythematosus. Am. J. Med. 85: 42-44 (1988).
Fu N, Khan S, Quinten E, de Graaf N, Pemberton AJ, Rivett AJ, Melief CJ, Ossendorp F. Effective CD8(+) T cell priming and tumor protection by enterotoxin B subunit-conjugated peptides targeted to dendritic cells. Vaccine 27: 5252-5258 (2009). *
Fu X, Tan L, Liu S, Li H, Chen L, Qin J, Wu M, Wang H. A novel diagnostic marker, p28GANK distinguishes hepatocellular carcinoma from potential mimics. J. Cancer Res. Clin. Oncol. 130: 514-520 (2004). *
Fu Y, Nathan DM, Li F, Li X, Faustman DL. Defective major histocompatibility complex class I expression on lymphoid cells in autoimmunity. J. Clin. Invest. 91: 2301-2307 (1993). *
Fudaba Y, Onoe T, Chittenden M, Shimizu A, Shaffer JM, Bronson R, Sykes M. Abnormal regulatory and effector T cell function predispose to autoimmunity following xenogeneic thymic transplantation. J. Immunol. 181: 7649-7659 (2008). *
Fuentes-Mattei E, Rivera E, Gioda A, Sanchez-Rivera D, Roman-Velazquez FR, Jimenez-Velez BD. Use of human bronchial epithelial cells (BEAS-2B) to study immunological markers resulting from exposure to PM(2.5) organic extract from Puerto Rico. Toxicol. Appl. Pharmacol. Dec 16 [Epub ahead of print] (2009). *
Fuertes MB, Girart MV, Molinero LL, Domaica CI, Rossi LE, Barrio MM, Mordoh J, Rabinovich GA, Zwirner NW. Intracellular retention of the NKG2D ligand MHC class I chain-related gene A in human melanomas confers immune privilege and prevents NK cell-mediated cytotoxicity. J. Immunol. 180: 4606-4614 (2008). *
Fugger L, Michie SA, Rulifson I, Lock CB, McDevitt GS. Expression of HLA-DR4 and human CD4 transgenes in mice determines the variable region beta-chain T-cell repertoire and mediates an HLA-DR-restricted immune response. Proc. Natl. Acad. Sci. U.S.A. 91: 6151-6155 (1994). *
Fujii S. Application of natural killer T-cells to posttransplantation immunotherapy. Int. J. Hematol. 81: 1-5 (2005).
Fujii T, Iida Y, Yomogida M, Ikeda K, Haga T, Jikumaru Y, Ninami M, Nishimura N, Kodera Y, Inada Y, Shirai T, Hirose S, Nishimura H. Genetic control of the spontaneous activation of CD4(+) Th cells in systemic lupus erythematosus-prone (NZB x NZW) F(1) mice. Genes Immun. 7: 647-654 (2006). *
Fujikado N, Saijo S, Iwakura Y. Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis. Arthritis Res. Ther. 8: R100 (2006). *
Fujimura T, Hirose S, Jiang Y, Kodera S, Ohmuro H, Zhang D, Hamano Y, Ishida H, Furukawa S, Shirai T. Dissection of the effects of tumor necrosis factor-alpha and class II gene polymorphisms within the MHC on murine systemic lupus erythematosus (SLE). Int. Immunol. 10: 1467-1472 (1998). *
Fujisawa T, Ikegami H, Noso S, Yamaji K, Nojima K, Babaya N, Itoi-Babaya M, Hiromine Y, Kobayashi M, Makino S, Ogihara T. MHC-linked susceptibility to type 1 diabetes in the NOD mouse: further localization of Idd16 by subcongenic analysis. Ann. N. Y. Acad. Sci. 1079: 118-121 (2006). *
Fujishiro J, Suzuki C, Kudou S, Yasue T, Hakamata Y, Takahashi M, Murakami T, Hashizume K, Kobayashi E. Change from cyclosporine to combination therapy of mycophenolic acid with the new sphingosine-1-phosphate receptor agonist, KRP-203, prevents host nephrotoxicity and transplant vasculopathy in rats. J. Heart Lung Transplant. 25: 825-833 (2006).
Fujita K, Naito S, Okabe N, Yao T. Immunological studies in Crohn's disease. I. Association with HLA systems in the Japanese. J. Clin. Lab. Immunol. 14: 99-102 (1984).
Fukami N, Ramachandran S, Saini D, Walter M, Chapman W, Patterson GA, Mohanakumar T. Antibodies to MHC class I induce autoimmunity: role in the pathogenesis of chronic rejection. J. Immunol. 182: 309-318 (2009). *
Fukami-Kobayashi K, Shiina T, Anzai T, Sano K, Yamazaki M, Inoko H, Tateno Y. Genomic evolution of MHC class I region in primates. Proc. Natl. Acad. Sci. U.S.A. 102: 9230-9234 (2005). *
Fukasawa T, Murashima K, Matsumoto I, Hosono A, Ohara H, Nojiri C, Koga J, Kubota H, Kanegae M, Kaminogawa S, Abe K, Kono T. Identification of marker genes for intestinal immunomodulating effect of a fructooligosaccharide by DNA microarray analysis. J. Agric. Food Chem. 55: 3174-3179 (2007). *
Fuller MJ, Shoukry NH, Gushima T, Bowen DG, Callendret B, Campbell KJ, Hasselschwert DL, Hughes AL, Walker CM. Selection-driven immune escape is not a significant factor in the failure of CD4 T cell responses in persistent hepatitis C virus infection. Hepatology 51: 378-387 (2010). *
Fulton A, Miller F, Weise A, Wei WZ. Prospects of controlling breast cancer metastasis by immune intervention. Breast Dis. 26: 115-127 (2007).
Furmanski AL, Bartok I, Chai JG, Singh Y, Ferreira C, Scott D, Holland SJ, Bourdeaux C, Crompton T, Dyson J. Peptide-specific, TCR-alpha-driven, coreceptor-independent negative selection in TCR alpha-chain transgenic mice. J. Immunol. 184: 650-657 (2010).
Furugaki K, Pokorna K, le Pogam C, Aoki M, Reboul M, Bajzik V, Krief P, Janin A, Noguera ME, West R, Charron D, Chomienne C, Pla M, Moins-Teisserenc H, Padua RA. DNA vaccination with all-trans retinoic acid treatment induces long term survival and elicits specific immune responses requiring CD4+ and CD8+ T-cell activation in an acute promyelocytic leukemia mouse model. Blood Nov 19 [Epub ahead of print] (2009). *
Furuya T, Joe B, Salstrom JL, Hashiramoto A, Dobbins DE, Wilder RL, Remmers EF. Polymorphisms of the tumor necrosis factor alpha locus among autoimmune disease susceptible and resistant inbred rat strains. Genes Immun. 2: 229-232 (2001). *
Furuya T, Salstrom JL, McCall-Vining S, Cannon GW, Joe B, Remmers EF, Griffiths MM, Wilder RL. Genetic dissection of a rat model for rheumatoid arthritis: significant gender influences on autosomal modifier loci. Hum. Mol. Genet. 9: 2241-2250 (2000). *
Fussell H, Nesbeth D, Lenart I, Campbell EC, Lynch S, Santos S, Gould K, Powis SJ, Antoniou AN. Novel detection of in vivo HLA-B27 conformations correlates with ankylosing spondylitis association. Arthritis Rheum. 58: 3419-3424 (2008). *
Gaertner S, De Graaf KL, Wienhold W, Wiesmuller KH, Melms A, Weissert R. Lack of pathogenicity of immunodominant T and B cell determinants of the nicotinic acetylcholine receptor epsilon-chain. J. Neuroimmunol. 152: 44-56 (2004).
Gagnon SJ, Borbulevych OY, Davis-Harrison RL, Baxter TK, Clemens JR, Armstrong KM, Turner RV, Damirjian M, Biddison WE, Baker BM. Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants. J. Mol. Biol. 353: 556-573 (2005). *
Gakamsky DM, Lewitzki E, Grell E, Saulquin X, Malissen B, Montero-Julian F, Bonneville M, Pecht I. Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor. Proc. Natl. Acad. Sci. U.S.A. 104: 16639-16644 (2007). *
Galbraith GM, Pandey JP. Tumor necrosis factor alpha (TNF-alpha) gene polymorphism in alopecia areata. Hum. Genet. 96: 433-436 (1995).
Galea I, Bernardes-Silva M, Forse PA, van Rooijen N, Liblau RS, Perry VH. An antigen-specific pathway for CD8 T cells across the blood-brain barrier. J. Exp. Med. 204: 2023-2030 (2007). *
Galhenage SP, Viiala CH, Olynyk JK. Screening for hemochromatosis: patients with liver disease, families, and populations. Curr. Gastroenterol. Rep. 6: 44-51 (2004).
Gallego F, Gelpi C. The IL-12 role in donor cell engraftment in a murine model of semiallogenic GVH disease with signs of autoimmune disease. Autoimmunity 37: 155-170 (2004).
Gambelunghe G, Brozzetti A, Ghaderi M, Candeloro P, Tortoioli C, Falorni A. MICA gene polymorphism in the pathogenesis of type 1 diabetes. Ann. N. Y. Acad. Sci. 1110: 92-98 (2007). *
Gambelunghe G, Brozzetti AL, Ghaderi M, Tortoioli C, Falorni A. MICA A8: a new allele within MHC class I chain-related A transmembrane region with eight GCT repeats. Hum. Immunol. 67: 1005-1007 (2006).
Gambelunghe G, Falorni A, Ghaderi M, Laureti S, Tortoioli C, Santeusanio F, Brunetti P, Sanjeevi CB. Microsatellite polymorphism of the MHC class I chain-related (MIC-A and MIC-B) genes marks the risk for autoimmune Addison's disease. J. Clin. Endocrinol. Metab. 84: 3701-3707 (1999). *
Gambelunghe G, Gerli R, Bartoloni Bocci E, Del Sindaco P, Ghaderi M, Sanjeevi CB, Bistoni O, Bini V, Falorni A. Contribution of MHC class I chain-related A (MICA) gene polymorphism to genetic susceptibility for systemic lupus erythematosus. Rheumatology (Oxford) 44: 287-292 (2005). *
Gambelunghe G, Ghaderi M, Cosentino A, Falorni A, Brunetti P, Falorni A, Sanjeevi CB. Association of MHC class I chain-related A (MIC-A) gene polymorphism with type I diabetes. Diabetologia 43: 507-514 (2000). *
Gambelunghe G, Ghaderi M, Tortoioli C, Falorni A, Santeusanio F, Brunetti P, Sanjeevi CB, Falorni A; Umbria Type 1 Diabetes Registry. Two distinct MICA gene markers discriminate major autoimmune diabetes types. J. Clin. Endocrinol. Metab. 86: 3754-3760 (2001). *
Gammon DC, Bhatt MS, Patel B, Anderson M, Van Horn A, Glantz MJ. Managing reduced methotrexate clearance in a patient with a heterozygous methylenetetrahydrofolate reductase gene polymorphism. J. Oncol. Pharm. Pract. 14: 153-156 (2008).
Ganesh BB, Cheatem DM, Sheng JR, Vasu C, Prabhakar BS. GM-CSF-induced CD11c+CD8a--dendritic cells facilitate Foxp3+ and IL-10+ regulatory T cell expansion resulting in suppression of autoimmune thyroiditis. Int. Immunol. 21: 269-282 (2009). *
Gao B, Radaeva S, Jeong WI. Activation of natural killer cells inhibits liver fibrosis: a novel strategy to treat liver fibrosis. Expert Rev. Gastroenterol. Hepatol. 1: 173-180 (2007).
Gao B, Williams A, Sewell A, Elliott T. Generation of a functional, soluble tapasin protein from an alternatively spliced mRNA. Genes Immun. 5: 101-108 (2004). *
Gao W, Lu Y, El Essawy B, Oukka M, Kuchroo VK, Strom TB. Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. Am. J. Transplant. 7: 1722-1732 (2007).
Garaci E. Thymosin alpha 1: a historical overview. Ann. N. Y. Acad. Sci. 1112: 14-20 (2007). *
Garantziotis S, Palmer SM, Snyder LD, Ganous T, Chen BJ, Wang T, Cook DN, Schwartz DA. Alloimmune lung injury induced by local innate immune activation through inhaled lipopolysaccharide. Transplantation 84: 1012-1019 (2007).
Garapati VP, Lefranc MP. IMGT Colliers de Perles and IgSF domain standardization for T cell costimulatory activatory (CD28, ICOS) and inhibitory (CTLA4, PDCD1 and BTLA) receptors. Dev. Comp. Immunol. 31: 1050-1072 (2007).
Garchon HJ, Bach JF. The contribution of non-MHC genes to susceptibility to autoimmune diseases. Hum. Immunol. 32: 1-30 (1991).
Garcia KC, Adams JJ, Feng D, Ely LK. The molecular basis of TCR germline bias for MHC is surprisingly simple. Nat. Immunol. 10: 143-147 (2009). *
Garcia Z, Pradelli E, Celli S, Beuneu H, Simon A, Bousso P. Competition for antigen determines the stability of T cell-dendritic cell interactions during clonal expansion. Proc. Natl. Acad. Sci. U.S.A. 104: 4553-4558 (2007). *
Garcia-Borges CN, Phanavanh B, Crew MD. Characterization of porcine TAP genes: alternative splicing of TAP1. Immunogenetics 58: 374-382 (2006). *
Garcia-Gonzalez E, Castro-Llamas J, Karchmer S, Zuniga J, de Oca DM, Ambaz M, Bolanos R, Granados J. Class II major histocompatibility complex typing across the ethnic barrier in pemphigoid gestationis. A study in Mexicans. Int. J. Dermatol. 38: 46-51 (1999). *
Gardiner A, Richards KA, Sant AJ, Arneson LS. Conformation of MHC class II I-Ag7 is sensitive to the P9 anchor amino acid in bound peptide. Int. Immunol. 19: 1103-1113 (2007). *
Gardiner KR, Crockard AD, Halliday MI, Rowlands BJ. Class II major histocompatibility complex antigen expression on peripheral blood monocytes in patients with inflammatory bowel disease. Gut 35: 511-516 (1994). *
Garino E, Miertus J, Berrino M, Bertinetto F, Caropreso P, Gay V, Mazzola G, Tondat F, Frecer V, Miertus S, Amoroso A. Molecular aspects of a novel HLA-A*02 allele (A*0297): the first HLA class I allele mutated at codon 232. Tissue Antigens 69: 342-347 (2007). *
Garrido C, Algarra I, Maleno I, Stefanski J, Collado A, Garrido F, Garcia-Lora AM. Alterations of HLA class I expression in human melanoma xenografts in immunodeficient mice occur frequently and are associated with higher tumorigenicity. Cancer Immunol. Immunother. 59: 13-26 (2010).
Garrido F, Cabrera T, Aptsiauri N. "Hard" and "soft" lesions underlying the hla class I alterations in cancer cells: implications for immunotherapy. Int. J. Cancer Feb 22 [Epub ahead of print] (2010).
Garrity-Park MM, Loftus Jr EV, Sandborn WJ, Bryant S, Smyrk TC. MHC class II alleles in ulcerative colitis-associated colorectal cancer. Gut 58: 1226-1233 (2009). *
Garver-Apgar CE, Gangestad SW, Thornhill R, Miller RD, Olp JJ. Major histocompatibility complex alleles, sexual responsivity, and unfaithfulness in romantic couples. Psychol. Sci. 17: 830-835 (2006). *
Gaseitsiwe S, Maeurer MJ. Identification of MHC class II binding peptides: microarray and soluble MHC class II molecules. Methods Mol. Biol. 524: 417-426 (2009).
Gaseitsiwe S, Valentini D, Mahdavifar S, Reilly M, Ehrnst A, Maeurer M. Peptide microarray-based identification of Mycobacterium tuberculosis epitope binding to HLA-DRB1*0101, DRB1*1501 and DRB1*0401. Clin. Vaccine Immunol. Oct 28 [Epub ahead of print] (2009). *
Gaston H. Mechanisms of disease: the immunopathogenesis of spondyloarthropathies. Nat. Clin. Pract. Rheumatol. 2: 383-392 (2006). *
Gatzka M, Walsh CM. Apoptotic signal transduction and T cell tolerance. Autoimmunity 40: 442-452 (2007).
Gaudenzio N, Espagnole N, Mars LT, Liblau R, Valitutti S, Espinosa E. Cell-cell cooperation at the T helper cell/mast cell immunological synapse. Blood 114: 4979-4988 (2009). *
Gaudieri S, Kulski JK, Dawkins RL, Gojobori T. Different evolutionary histories in two subgenomic regions of the major histocompatibility complex. Genome Res. 9: 541-549 (1999). *
Gautier AC, Devys A, Cheneau ML, Simon PH, Martin C, Allard S, Hourmant M, Bignon JD. MICA compatibility and immunization in third kidney transplantations. Transplant. Proc. 41: 663-665 (2009). *
Ge Y, Rampy BA, Wang HL, Xiao SY. Reduced CD1d expression in colonic epithelium in microscopic colitis. Appl. Immunohistochem. Mol. Morphol. 14: 309-313 (2006).
Gebe JA, Kwok WW. Tracking antigen specific CD4+ T-cells with soluble MHC molecules. Methods Mol. Med. 136: 39-50 (2007).
Geboes K, Rutgeerts P, Penninckx F, Desmet V, Vantrappen G. Changes in small intestinal epithelial expression of MHC class II antigen after terminal ileal resection for Crohn's disease. Int. J. Colorectal Dis. 3: 102-108 (1988).
Gebreselassie D, Spiegel H, Vukmanovic S. Sampling of major histocompatibility complex class I-associated peptidome suggests relatively looser global association of HLA-B*5101 with peptides. Hum. Immunol. 67: 894-906 (2006).
Geissler I, Collins L, Schofield R, Fabre JW. In vivo suppression of major histocompatibility complex class II expression on porcine vascular endothelial cells by an HMG-CoA reductase inhibitor. Transplantation 81: 922-926 (2006).
Geissmann F, Revy P, Brousse N, Lepelletier Y, Folli C, Durandy A, Chambon P, Dy M. Retinoids regulate survival and antigen presentation by immature dendritic cells. J. Exp. Med. 198: 623-634 (2003). *
Gelderman KA, Hultqvist M, Olsson LM, Bauer K, Pizzolla A, Olofsson P, Holmdahl R. Rheumatoid arthritis: the role of reactive oxygen species in disease development and therapeutic strategies. Antioxid. Redox Signal. 9: 1541-1568 (2007).
Geluk A, van Meijgaarden KE, Franken KL, Drijfhout JW, D'Souza S, Necker A, Huygen K, Ottenhoff TH. Identification of major epitopes of Mycobacterium tuberculosis AG85B that are recognized by HLA-A*0201-restricted CD8+ T cells in HLA-transgenic mice and humans. J. Immunol. 165: 6463-6471 (2000). *
Genin E, Babron MC, McDermott MF, Mulcahy B, Waldron-Lynch F, Adams C, Clegg DO, Ward RH, Shanahan F, Molloy MG, O'Gara F, Clerget-Darpoux F. Modelling the major histocompatibility complex susceptibility to RA using the MASC method. Genet. Epidemiol. 15: 419-430 (1998).
Genton C, Wang Y, Izui S, Malissen B, Delsol G, Fournie GJ, Malissen M, Acha-Orbea H. The Th2 lymphoproliferation developing in LatY136F mutant mice triggers polyclonal B cell activation and systemic autoimmunity. J. Immunol. 177: 2285-2293 (2006). *
George AJ, Stark J, Chan C. Understanding specificity and sensitivity of T-cell recognition. Trends Immunol. 26: 653-659 (2005). *
Georgel P, Macquin C, Bahram S. The heterogeneous allelic repertoire of human Toll-like receptor (TLR) genes. PLoS One 4: e7803 (2009). *
Geraghty DE, Daza R, Williams LM, Vu Q, Ishitani A. Genetics of the immune response: identifying immune variation within the MHC and throughout the genome. Immunol. Rev. 190: 69-85 (2002). *
Gerber BO, Pichler WJ. Noncovalent interactions of drugs with immune receptors may mediate drug-induced hypersensitivity reactions. AAPS J. 8: E160-E165 (2006). *
Germain RN. T-cell development and the CD4-CD8 lineage decision. Nat. Rev. Immunol. 2: 309-322 (2002). *
German AC, Myint KS, Mai NT, Pomeroy I, Phu NH, Tzartos J, Winter P, Collett J, Farrar J, Barrett A, Kipar A, Esiri MM, Solomon T. A preliminary neuropathological study of Japanese encephalitis in humans and a mouse model. Trans. R. Soc. Trop. Med. Hyg. 100: 1135-1145 (2006). *
Gershwin ME. Primary biliary cirrhosis: from induction through destruction. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 39-40 (2004). *
Gershwin ME, Leung PS, Li H, Seldin MF. Primary biliary cirrhosis and autoimmunity: evaluating the genetic risk. Isr. Med. Assoc. J. 2 Suppl: 7-10 (2000).
Gershwin ME, Mackay IR. Primary biliary cirrhosis: paradigm or paradox for autoimmunity. Gastroenterology 100: 822-833 (1991).
Ghaderi M, Gambelunghe G, Tortoioli C, Brozzetti A, Jatta K, Gharizadeh B, De Bellis A, Pecori Giraldi F, Terzolo M, Betterle C, Falorni A. MHC2TA single nucleotide polymorphism and genetic risk for autoimmune adrenal insufficiency. J. Clin. Endocrinol. Metab. 91: 4107-4111 (2006). *
Ghosn EE, Almeida SR. Nitric oxide-dependent killing of Cryptococcus neoformans by B-1-derived mononuclear phagocyte. J. Leukoc. Biol. 80: 36-44 (2006). *
Giacconi R, Cipriano C, Muti E, Costarelli L, Malavolta M, Caruso C, Lio D, Mocchegiani E. Involvement of -308 TNF-alpha and 1267 Hsp70-2 polymorphisms and zinc status in the susceptibility of coronary artery disease (CAD) in old patients. Biogerontology 7: 347-356 (2006). *
Giarratana N, Penna G, Adorini L. Animal models of spontaneous autoimmune disease: type 1 diabetes in the nonobese diabetic mouse. Methods Mol. Biol. 380: 285-312 (2007).
Gijzen K, Cambi A, Torensma R, Figdor CG. C-type lectins on dendritic cells and their interaction with pathogen-derived and endogenous glycoconjugates. Curr. Protein Pept. Sci. 7: 283-294 (2006).
Gilchrist FC, Bunn C, Foley PJ, Lympany PA, Black CM, Welsh KI, du Bois RM. Class II HLA associations with autoantibodies in scleroderma: a highly significant role for HLA-DP. Genes Immun. 2: 76-81 (2001). *
Gilhar A, Kalish RS. Alopecia areata: a tissue specific autoimmune disease of the hair follicle. Autoimmun. Rev. 5: 64-69 (2006).
Gilliam BE, Wolff AE, Moore TL. Partial C4 deficiency in juvenile idiopathic arthritis patients. J. Clin. Rheumatol. 13: 256-260 (2007).
Giorgini A, Noble A. Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts. J. Leukoc. Biol. 82: 1053-1061 (2007). *
Giraud M, Vandiedonck C, Garchon HJ. Genetic factors in autoimmune myasthenia gravis. Ann. N. Y. Acad. Sci. 1132: 180-192 (2008). *
Giuliani C, Bucci I, Montani V, Singer D, Monaco F, Kohn L, Napolitano G. Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole. J. Endocrinol. 204: 57-66 (2010). *
Giuliani C, Saji M, Bucci I, Fiore G, Liberatore M, Singer DS, Monaco F, Kohn LD, Napolitano G. Transcriptional regulation of major histocompatibility complex class I gene by insulin and IGF-I in FRTL-5 thyroid cells. J. Endocrinol. 189: 605-615 (2006). *
Glant TT, Adarichev VA, Nesterovitch AB, Szanto S, Oswald JP, Jacobs JJ, Firneisz G, Zhang J, Finnegan A, Mikecz K. Disease-associated qualitative and quantitative trait loci in proteoglycan-induced arthritis and collagen-induced arthritis. Am. J. Med. Sci. 327: 188-195 (2004).
Glas J, Martin K, Brunnler G, Kopp R, Folwaczny C, Weiss EH, Albert ED. MICA, MICB and C1_4_1 polymorphism in Crohn's disease and ulcerative colitis. Tissue Antigens 58: 243-249 (2001). *
Glas J, Torok HP, Tonenchi L, Wetzke M, Beynon V, Teshome MY, Cotofana S, Schiemann U, Griga T, Klein W, Epplen JT, Folwaczny C, Folwaczny M, Mussack T, Weiss EH. The 14-bp deletion polymorphism in the HLA-G gene displays significant differences between ulcerative colitis and Crohn's disease and is associated with ileocecal resection in Crohn's disease. Int. Immunol. 19: 621-626 (2007). *
Glass EJ. Genetic variation and responses to vaccines. Anim. Health Res. Rev. 5: 197-208 (2004).
Gnjec A, D'Costa KJ, Laws SM, Hedley R, Balakrishnan K, Taddei K, Martins G, Paton A, Verdile G, Gandy SE, Broe GA, Brooks WS, Bennett H, Piguet O, Price P, Miklossy J, Hallmayer J, McGeer PL, Martins RN. Association of alleles carried at TNFA -850 and BAT1 -22 with Alzheimer's disease. J. Neuroinflammation 5: 36 (2008). *
Go RC, Alarcon GS, Acton RT, Koopman WJ, Vittor VJ, Barger BO. Analyses of HLA linkage in white families with multiple cases of seropositive rheumatoid arthritis. Arthritis Rheum. 30: 1115-1123 (1987).
Godo M, Sessler T, Hama P. Role of invariant natural killer T (iNKT) cells in systemic lupus erythematosus. Curr. Med. Chem. 15: 1778-1787 (2008).
Goebel J, Forrest K, Flynn D, Rao R, Roszman TL. Lipid rafts, major histocompatibility complex molecules, and immune regulation. Hum. Immunol. 63: 813-820 (2002).
Gold B, Merriam JE, Zernant J, Hancox LS, Taiber AJ, Gehrs K, Cramer K, Neel J, Bergeron J, Barile GR, Smith RT, Hageman GS, Dean M, Allikmets R, Chang S, Yannuzzi LA, Merriam JC, Barbazetto I, Lerner LE, Russell S, Hoballah J, Hageman J, Stockman H. Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration. Nat. Genet. 38: 458-462 (2006). *
Gold MC, Robinson TL, Cook MS, Byrd LK, Ehlinger HD, Lewinsohn DM, Lewinsohn DA. Human neonatal dendritic cells are competent in MHC class I antigen processing and presentation. PLoS ONE 2: e957 (2007). *
Goldberg AC, Bittencourt PL, Oliveira LC, Ramasawmy R, Marin ML, Palacios SA, Kalil J, Porta G. Autoimmune hepatitis in Brazil: an overview. Scand. J. Immunol. 66: 208-216 (2007). *
Goldstein R, Moulds JM, Smith CD, Sengar DP. MHC studies of the primary antiphospholipid antibody syndrome and of antiphospholipid antibodies in systemic lupus erythematosus. J. Rheumatol. 23: 1173-1179 (1996).
Goldstein R, Sengar DP. Comparative studies of the major histocompatibility complex in French Canadian and non-French Canadian Caucasians with systemic lupus erythematosus. Arthritis Rheum. 36: 1121-1127 (1993).
Gomes AQ, Correia DV, Silva-Santos B. Non-classical major histocompatibility complex proteins as determinants of tumour immunosurveillance. EMBO Rep. 8: 1024-1030 (2007). *
Gomez LM, Camargo JF, Castiblanco J, Ruiz-Narvaez EA, Cadena J, Anaya JM. Analysis of IL1B, TAP1, TAP2 and IKBL polymorphisms on susceptibility to tuberculosis. Tissue Antigens 67: 290-296 (2006). *
Gomez-Garcia M, Oliver J, Marquez A, Mendoza JL, Lopez-Nevot MA, Fernandez-Arquero M, Gonzalez-Escribano MF, Diaz-Rubio M, Concha EG, Urcelay E, Martin J, Martinez A. Strong protective effect of DR3 against ulcerative colitis in the Spanish population. Am. J. Gastroenterol. 102: 2762-2766 (2007). *
Gonen-Gross T, Mandelboim O. HLA-G complexes are observed on the cell surface. Hum. Immunol. 68: 227-232 (2007).
Gongora R, Zaleska-Rutczynska Z, Takami K, Figueroa F, Klein J. Linkage of RXRB-like genes to class I and not to class II MHC genes in the zebrafish. Immunogenetics 48: 141-143 (1998).
Gony J, Vexiau P, Lhomme C, Marcelli A, Poirier JC, Bochu V, Cathelineau G, Assan R, Deschamps I, Hors J. MHC classes I, II, III antigens study in 70 insulin-dependent diabetics with associated auto-immune diseases. Tissue Antigens 31: 229-234 (1988).
Gonzalez S, Brautbar C, Martinez-Borra J, Lopez-Vazquez A, Segal R, Blanco-Gelaz MA, Enk CD, Safriman C, Lopez-Larrea C. Polymorphism in MICA rather than HLA-B/C genes is associated with psoriatic arthritis in the Jewish population. Hum. Immunol. 62: 632-638 (2001).
Gonzalez S, Groh V, Spies T. Immunobiology of human NKG2D and its ligands. Curr. Top. Microbiol. Immunol. 298: 121-138 (2006).
Gonzalez S, Martinez-Borra J, Torre-Alonso JC, Gonzalez-Roces S, Sanchez del Rio J, Rodriguez Perez A, Brautbar C, Lopez-Larrea C. The MICA-A9 triplet repeat polymorphism in the transmembrane region confers additional susceptibility to the development of psoriatic arthritis and is independent of the association of Cw*0602 in psoriasis. Arthritis Rheum. 42: 1010-1016 (1999). *
Gonzalez S, Rodrigo L, Lopez-Vazquez A, Fuentes D, Agudo-Ibanez L, Rodriguez-Rodero S, Fdez-Morera JL, Martinez-Borra J, Lopez-Larrea C. Association of MHC class I related gene B (MICB) to celiac disease. Am. J. Gastroenterol. 99: 676-680 (2004). *
Gonzalez-Escribano MF, Rodriguez MR, Aguilar F, Alvarez A, Sanchez-Roman J, Nunez-Roldan A. Lack of association of MICA transmembrane region polymorphism and Behcet's disease in Spain. Tissue Antigens 54: 278-281 (1999). *
Gonzalez-Gay MA, Rueda B, Vilchez JR, Lopez-Nevot MA, Robledo G, Ruiz MP, Fernandez O, Garcia-Porrua C, Gonzalez-Escribano MF, Martin J. Contribution of MHC class I region to genetic susceptibility for giant cell arteritis. Rheumatology (Oxford) 46: 431-434 (2007). *
Gonzalez-Roldan N, Ferat-Osorio E, Aduna-Vicente R, Wong-Baeza I, Esquivel-Callejas N, Astudillo-de la Vega H, Sanchez-Fernandez P, Arriaga-Pizano L, Villasis-Keever MA, Lopez-Macias C, Isibasi A. Expression of triggering receptor on myeloid cell 1 and histocompatibility complex molecules in sepsis and major abdominal surgery. World J. Gastroenterol. 11: 7473-7479 (2005). *
Good RA. Cellular immunology in a historical perspective. Immunol. Rev. 185: 136-158 (2002). *
Good RA. Progress toward production of immunologic tolerance with no or minimal toxic immunosuppression for prevention of immunodeficiency and autoimmune diseases. World J. Surg. 24: 797-810 (2000). *
Goodsell DS. The molecular perspective: major histocompatibility complex. Oncologist 10: 80-81 (2005). *
Gores GJ, Moore SB, Fisher LD, Powell FC, Dickson ER. Primary biliary cirrhosis: associations with class II major histocompatibility complex antigens. Hepatology 7: 889-892 (1987).
Gorham JD. Chapter 5. Adaptive immunity in the liver. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 61-70 (2007). *
Gorodezky C, Olivo A, Alaez C, Vazquez MN, de la Rosa G, Debaz H, Robles C, Altamirano N, Layrisse Z, Balducci PL, Dominguez E, Herrera F, Montagnani S, Esparza B, Balbas O, Gunczler P, Lanes R, Amaro R, Zaro R, Fuenmayor V, Montoya F, Bedoya CI, et al. High- and low-risk molecular sequences in autoimmune diseases. An analysis of type I diabetes in Latin America. Gac. Med. Mex. 133 Suppl. 1: 125-132 (1997).
Goto K, Ota M, Maksymowych WP, Mizuki N, Yabuki K, Katsuyama Y, Kimura M, Inoko H, Ohno S. Association between MICA gene A4 allele and acute anterior uveitis in white patients with and without HLA-B27. Am. J. Ophthalmol. 126: 436-441 (1998).
Gottfried-Blackmore A, Kaunzner UW, Idoyaga J, Felger JC, McEwen BS, Bulloch K. Acute in vivo exposure to interferon-gamma enables resident brain dendritic cells to become effective antigen presenting cells. Proc. Natl. Acad. Sci. U.S.A. Nov 11 [Epub ahead of print] (2009). *
Gouin N, Deakin JE, Miska KB, Miller RD, Kammerer CM, Graves JA, VandeBerg JL, Samollow PB. Linkage mapping and physical localization of the major histocompatibility complex region of the marsupial Monodelphis domestica. Cytogenet. Genome Res. 112: 277-285 (2006).
Gourraud PA, Feolo M, Hoffman D, Helmberg W, Cambon-Thomsen A. The dbMHC microsatellite portal: a public resource for the storage and display of MHC microsatellite information. Tissue Antigens 67: 395-401 (2006). *
Gourraud PA, Hoffman D, Cambon-Thomsen A, Feolo M. 14th International HLA and Immunogenetics Workshop: report on mapping microsatellite markers in the major histocompatibility complex region. Tissue Antigens 69 Suppl. 1: 206-209 (2007). *
Gowthaman U, Agrewala JN. In silico tools for predicting peptides binding to HLA-class II molecules: more confusion than conclusion. J. Proteome Res. 7: 154-163 (2008). *
Goyos A, Ohta Y, Guselnikov S, Robert J. Novel nonclassical MHC class Ib genes associated with CD8 T cell development and thymic tumors. Mol. Immunol. 46: 1775-1786 (2009). *
Graham KL, Sanders N, Tan Y, Allison J, Kay TW, Coulson BS. Rotavirus infection accelerates type 1 diabetes in mice with established insulitis. J. Virol. 82: 6139-6149 (2008). *
Grant JF, Iwasawa T, Sinn HW, Siemens DR, Griffith TS, Takacs EB, Ratliff TL. Induction of protective immunity to RM-1 prostate cancer cells with ALVAC-IL-2/IL-12/TNF-alpha combination therapy. Int. J. Cancer 119: 2632-2641 (2006). *
Grant SF, Kristjansdottir H, Steinsson K, Blondal T, Yuryev A, Stefansson K, Gulcher JR. Long PCR detection of the C4A null allele in B8-C4AQ0-C4B1-DR3. J. Immunol. Methods 244: 41-47 (2000). *
Gras S, Kjer-Nielsen L, Burrows SR, McCluskey J, Rossjohn J. T-cell receptor bias and immunity. Curr. Opin. Immunol. 20: 119-125 (2008). *
Grau R, Lang KS, Wernet D, Lang P, Niethammer D, Pusch CM, Handgretinger R. Cytotoxic activity of natural killer cells lacking killer-inhibitory receptors for self-HLA class I molecules against autologous hematopoietic stem cells in healthy individuals. Exp. Mol. Pathol. 76: 90-98 (2004). *
Grauer O, Poschl P, Lohmeier A, Adema GJ, Bogdahn U. Toll-like receptor triggered dendritic cell maturation and IL-12 secretion are necessary to overcome T-cell inhibition by glioma-associated TGF-beta2. J. Neurooncol. 82: 151-161 (2007). *
Greene MT, Ercolini AM, Degutes M, Miller SD. Differential induction of experimental autoimmune encephalomyelitis by myelin basic protein molecular mimics in mice humanized for HLA-DR2 and an MBP(85-99)-specific T cell receptor. J. Autoimmun. 31: 399-407 (2008).
Greenfield EA, Nguyen KA, Kuchroo VK. CD28/B7 costimulation: a review. Crit. Rev. Immunol. 18: 389-418 (1998).
Greer KA, Higgins MA, Cox ML, Ryan TP, Berridge BR, Kashtan CE, Lees GE, Murphy KE. Gene expression analysis in a canine model of X-linked Alport syndrome. Mamm. Genome 17: 976-990 (2006). *
Greetham D, Ellis CD, Mewar D, Fearon U, Nic An Ultaigh S, Veale DJ, Guesdon F, Wilson AG. Functional characterisation of NF-kappaB inhibitor-like protein 1 (NFkappaBIL1), a candidate susceptibility gene for rheumatoid arthritis. Hum. Mol. Genet. 16: 3027-3036 (2007). *
Gregersen JW, Kranc KR, Ke X, Svendsen P, Madsen LS, Thomsen AR, Cardon LR, Bell JI, Fugger L. Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature 443: 574-577 (2006). *
Gregersen PK. Genetics of rheumatoid arthritis: confronting complexity. Arthritis Res. 1: 37-44 (1999). *
Gregersen PK. HLA class II polymorphism: implications for genetic susceptibility to autoimmune disease. Lab. Invest. 61: 5-19 (1989).
Gregersen PK, Behrens TW. Genetics of autoimmune diseases - disorders of immune homeostasis. Nat. Rev. Genet. 7: 917-928 (2006). *
Gregerson DS, Heuss ND, Lew KL, McPherson SW, Ferrington DA. Interaction of retinal pigmented epithelial cells and CD4 T cells leads to T-cell anergy. Invest. Ophthalmol. Vis. Sci. 48: 4654-4663 (2007). *
Gregerson DS, Kawashima H. APC derived from donor splenocytes support retinal autoimmune disease in allogeneic recipients. J. Leukoc. Biol. 76: 383-387 (2004). *
Gregerson DS, Lew KL, McPherson SW, Heuss ND, Ferrington DA. RPE cells resist bystander killing by CTLs, but are highly susceptible to antigen-dependent CTL killing. Invest. Ophthalmol. Vis. Sci. 47: 5385-5394 (2006). *
Gregory SG, Schmidt S, Seth P, Oksenberg JR, Hart J, Prokop A, Caillier SJ, Ban M, Goris A, Barcellos LF, Lincoln R, McCauley JL, Sawcer SJ, Compston DA, Dubois B, Hauser SL, Garcia-Blanco MA, Pericak-Vance MA, Haines JL. Interleukin 7 receptor alpha chain (IL7R) shows allelic and functional association with multiple sclerosis. Nat. Genet. 39: 1083-1091 (2007). *
Gregory WL, Daly AK, Dunn AN, Cavanagh G, Idle JR, James OF, Bassendine MF. Analysis of HLA-class-II-encoded antigen-processing genes TAP1 and TAP2 in primary biliary cirrhosis. Q. J. Med. 87: 237-244 (1994).
Grennan DM, Sanders PA. Rheumatoid arthritis. Baillieres Clin. Rheumatol. 2: 585-601 (1988).
Grennan DM, Sanders PA, Dyer PA, Harris R. HLA haplotype sharing by siblings with rheumatoid arthritis: evidence for genetic heterogeneity. Ann. Rheum. Dis. 45: 126-129 (1986). *
Greter M, Heppner FL, Lemos MP, Odermatt BM, Goebels N, Laufer T, Noelle RJ, Becher B. Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis. Nat. Med. 11: 328-334 (2005). *
Greve B, Reddy J, Waldner HP, Sobel RA, Kuchroo VK. Dissimilar background genes control susceptibility to autoimmune disease in the context of different MHC haplotypes: NOD.H-2(s) congenic mice are relatively resistant to both experimental autoimmune encephalomyelitis and type I diabetes. Eur. J. Immunol. 34: 1828-1838 (2004). *
Grewal IS, Flavell RA. The role of CD40 ligand in costimulation and T-cell activation. Immunol. Rev. 153: 85-106 (1996).
Griffith ME, Pusey CD. HLA genes in ANCA-associated vasculitides. Exp. Clin. Immunogenet. 14: 196-205 (1997).
Grigoriadis AE, Schellander K, Wang ZQ, Wagner EF. Osteoblasts are target cells for transformation in c-fos transgenic mice. J. Cell Biol. 122: 685-701 (1993). *
Groettrup M, Kirk CJ, Basler M. Proteasomes in immune cells: more than peptide producers? Nat. Rev. Immunol. 10: 73-78 (2010). *
Grogan PM, Katz JS. Inflammatory myopathies. Curr. Treat. Options Neurol. 6: 155-161 (2004).
Groh V, Wu J, Yee C, Spies T. Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 419: 734-738 (2002). *
Groneck L, Schrama D, Fabri M, Stephen TL, Harms F, Meemboor S, Hafke H, Bessler M, Becker JC, Kalka-Moll WM. Oligoclonal CD4+ T cells promote host memory immune responses to zwitterionic polysaccharide of Streptococcus pneumoniae. Infect. Immun. 77: 3705-3712 (2009). *
Grotenbreg GM, Roan NR, Guillen E, Meijers R, Wang JH, Bell GW, Starnbach MN, Ploegh HL. Discovery of CD8+ T cell epitopes in Chlamydia trachomatis infection through use of caged class I MHC tetramers. Proc. Natl. Acad. Sci. U.S.A. 105: 3831-3836 (2008). *
Grotzke JE, Harriff MJ, Siler AC, Nolt D, Delepine J, Lewinsohn DA, Lewinsohn DM. The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle. PLoS Pathog. 5: e1000374 (2009). *
Grubic Z, Peric P, Eeeuk-Jelicic E, Zunec R, Stingl K, Curkovic B, Kerhin-Brkljacic V. The MICA-A4 triplet repeats polymorphism in the transmembrane region confers additional risk for development of psoriatic arthritis in the Croatian population. Eur. J. Immunogenet. 31: 93-98 (2004). *
Grubic Z, Stingl K, Kerhin-Brkljacic V, Zunec R. The study of the extended haplotypes of rare HLA-B*2730 allele using microsatellite loci. Tissue Antigens 71: 514-519 (2008). *
Grueter B, Petter M, Egawa T, Laule-Kilian K, Aldrian CJ, Wuerch A, Ludwig Y, Fukuyama H, Wardemann H, Waldschuetz R, Moroy T, Taniuchi I, Steimle V, Littman DR, Ehlers M. Runx3 regulates integrin alphaE/CD103 and CD4 expression during development of CD4-/CD8+ T cells. J. Immunol. 175: 1694-1705 (2005). *
Grundtman C, Lundberg IE. Pathogenesis of idiopathic inflammatory myopathies. Curr. Rheumatol. Rep. 8: 188-195 (2006).
Grunewald J, Eklund A, Olerup O. Human leukocyte antigen class I alleles and the disease course in sarcoidosis patients. Am. J. Respir. Crit. Care Med. 169: 696-702 (2004). *
Gu MM, Yuan WT, Yang JQ, Zhang J, Xiong XY, Yao FJ, Lu ZY, Wang ZG, Huang W, Fan LA. A genomewide scan for the susceptibility gene loci to ankylosing spondylitis in Chinese Han population. Yi Chuan Xue Bao 31: 217-220 (2004).
Gu X, Nei M. Locus specificity of polymorphic alleles and evolution by a birth-and-death process in mammalian MHC genes. Mol. Biol. Evol. 16: 147-156 (1999). *
Gubbels MR, Jorgensen TN, Metzger TE, Menze K, Steele H, Flannery SA, Rozzo SJ, Kotzin BL. Effects of MHC and gender on lupus-like autoimmunity in Nba2 congenic mice. J. Immunol. 175: 6190-6196 (2005). *
Gudjonsson JE, Karason A, Runarsdottir EH, Antons dottir AA, Hauksson VB, Jonsson HH, Gulcher J, Stefansson K, Valdimarsson H. Distinct clinical differences between HLA-Cw(*)0602 positive and negative psoriasis patients - an analysis of 1019 HLA-C- and HLA-B-typed patients. J. Invest. Dermatol. 126: 740-745 (2006). *
Guermonprez P, Valladeau J, Zitvogel L, Thery C, Amigorena S. Antigen presentation and T cell stimulation by dendritic cells. Annu. Rev. Immunol. 20: 621-667 (2002). *
Guerra RF, Imperadori L, Mantovani R, Dunalp DD, Finzi L. DNA compaction by the nuclear factor Y. Biophys. J. 93: 176-182 (2007). *
Guerra S, Najera JL, Gonzalez JM, Lopez L, Climent N, Gatell JM, Gallart T, Esteban M. Distinct gene expression profiling after infection of immature human monocyte-derived dendritic cells by the attenuated poxvirus vectors MVA and NYVAC. J. Virol. 81: 8707-8721 (2007). *
Guerreiro-Cacais AO, Uzunel M, Levitskaya J, Levitsky V. Inhibition of the heavy chain and beta2-microglobulin synthesis as a mechanism of MHC class I downregulation during Epstein-Barr virus replication. J. Virol. 81: 1390-1400 (2007). *
Guerrero A, Jain N, Wang X, Fries BC. Cryptococcus neoformans variants generated by phenotypic switching differ in virulence through effects on macrophage activation. Infect. Immun. Jan 4 [Epub ahead of print] (2010). *
Guethlein LA, Abi-Rached L, Hammond JA, Parham P. The expanded cattle KIR genes are orthologous to the conserved single-copy KIR3DX1 gene of primates. Immunogenetics 59: 517-522 (2007). *
Guidry PA, Stroynowski I. The murine family of gut-restricted class Ib MHC includes alternatively spliced isoforms of the proposed HLA-G homolog, "blastocyst MHC". J. Immunol. 175: 5248-5259 (2005). *
Guil S, Rodriguez-Castro M, Aguilar F, Villasevil EM, Anton LC, Del Val M. Need for tripeptidyl-peptidase II in major histocompatibility complex class I viral antigen processing when proteasomes are detrimental. J. Biol. Chem. 281: 39925-39934 (2006). *
Guimond M, Veenstra RG, Grindler DJ, Zhang H, Cui Y, Murphy RD, Kim SY, Na R, Hennighausen L, Kurtulus S, Erman B, Matzinger P, Merchant MS, Mackall CL. Interleukin 7 signaling in dendritic cells regulates the homeostatic proliferation and niche size of CD4+ T cells. Nat. Immunol. 10: 149-157 (2009). *
Guinazu N, Pellegrini A, Carrera-Silva EA, Aoki MP, Cabanillas AM, Girones N, Fresno M, Cano R, Gea S. Immunisation with a major Trypanosoma cruzi antigen promotes pro-inflammatory cytokines, nitric oxide production and increases TLR2 expression. Int. J. Parasitol. 37: 1243-1254 (2007). *
Gumperz JE, Parham P. The enigma of the natural killer cell. Nature 378: 245-248 (1995). *
Guo W, Smith D, Guth A, Aviszus K, Wysocki LJ. T cell tolerance to germline-encoded antibody sequences in a lupus-prone mouse. J. Immunol. 175: 2184-2190 (2005). *
Gupta M, Graham J, McNeeny B, Zarghami M, Landin-Olsson M, Hagopian WA, Palmer J, Lernmark A, Sanjeevi CB. MHC class I chain-related gene-A is associated with IA2 and IAA but not GAD in Swedish type 1 diabetes mellitus. Ann. N. Y. Acad. Sci. 1079: 229-239 (2006). *
Gupta M, Ludvigsson J, Sanjeevi CB. Frequency of MICA in all babies in Southeast Sweden (ABIS) positive for high-risk HLA-DQ associated with type 1 diabetes. Ann. N. Y. Acad. Sci. 1037: 138-144 (2004). *
Gupta M, Nikitina-Zake L, Zarghami M, Landin-Olsson M, Kockum I, Lernmark A, Sanjeevi CB. Association between the transmembrane region polymorphism of MHC class I chain related gene-A and type 1 diabetes mellitus in Sweden. Hum. Immunol. 64: 553-561 (2003).
Gupta S, Singh RK, Dastidar S, Ray A. Cysteine cathepsin S as an immunomodulatory target: present and future trends. Expert Opin. Ther. Targets 12: 291-299 (2008).
Gur C, Karussis D, Golden E, Doron S, Ilan Y, Safadi R. Amelioration of experimental colitis by Copaxone is associated with class-II-restricted CD4 immune blocking. Clin. Immunol. 118: 307-316 (2006). *
Guzylack-Piriou L, Piersma S, McCullough K, Summerfield A. Role of natural interferon-producing cells and T lymphocytes in porcine monocyte-derived dendritic cell maturation. Immunology 118: 78-87 (2006). *
Haas JP, Kimura A, Andreas A, Hochberger M, Keller E, Brunnler G, Bettinotti MP, Nevinny-Stickel C, Hildebrandt B, Sierp G, et al. Polymorphism in the upstream regulatory region of DQA1 genes and DRB1, QAP, DQA1, and DQB1 haplotypes in the German population. Hum. Immunol. 39: 31-40 (1994).
Habtezion A, Toivola DM, Butcher EC, Omary MB. Keratin-8-deficient mice develop chronic spontaneous Th2 colitis amenable to antibiotic treatment. J. Cell Sci. 118: 1971-1980 (2005). *
Hacini-Rachinel F, Nancey S, Boschetti G, Sardi F, Doucet-Ladeveze R, Durand PY, Flourie B, Kaiserlian D. CD4+ T cells and Lactobacillus casei control relapsing colitis mediated by CD8+ T Cells. J. Immunol. 183: 5477-5486 (2009).
Hack N, Angra S, McKnight T, Denhollander N, Cardella CJ. HLA class II-like antiidiotypic antibodies from highly sensitized patients inhibit T-cell alloresponses. Am. J. Transplant. 8: 111-120 (2008).
Hadrup SR, Toebes M, Rodenko B, Bakker AH, Egan DA, Ovaa H, Schumacher TN. High-throughput T-cell epitope discovery through MHC peptide exchange. Methods Mol. Biol. 524: 383-405 (2009). *
Hafler DA, Slavik JM, Anderson DE, O'Connor KC, De Jager P, Baecher-Allan C. Multiple sclerosis. Immunol. Rev. 204: 208-231 (2005). *
Hager-Theodorides AL, Furmanski AL, Ross SE, Outram SV, Rowbotham NJ, Crompton T. The Gli3 transcription factor expressed in the thymus stroma controls thymocyte negative selection via hedgehog-dependent and -independent mechanisms. J. Immunol. 183: 3023-3032 (2009).
Hahm KB, Im YH, Parks TW, Park SH, Markowitz S, Jung HY, Green J, Kim SJ. Loss of transforming growth factor beta signalling in the intestine contributes to tissue injury in inflammatory bowel disease. Gut 49: 190-198 (2001). *
Hahn BH, Ebling F, Singh RR, Singh RP, Karpouzas G, La Cava A. Cellular and molecular mechanisms of regulation of autoantibody production in lupus. Ann. N. Y. Acad. Sci. 1051: 433-441 (2005). *
Hahn M, Nicholson MJ, Pyrdol J, Wucherpfennig KW. Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor. Nat. Immunol. 6: 490-496 (2005). *
Haines JL, Bradford Y, Garcia ME, Reed AD, Neumeister E, Pericak-Vance MA, Rimmler JB, Menold MM, Martin ER, Oksenberg JR, Barcellos LF, Lincoln R, Hauser SL; Multiple Sclerosis Genetics Group. Multiple susceptibility loci for multiple sclerosis. Hum. Mol. Genet. 11: 2251-2256 (2002). *
Haines JL, Terwedow HA, Burgess K, Pericak-Vance MA, Rimmler JB, Martin ER, Oksenberg JR, Lincoln R, Zhang DY, Banatao DR, Gatto N, Goodkin DE, Hauser SL. Linkage of the MHC to familial multiple sclerosis suggests genetic heterogeneity. The Multiple Sclerosis Genetics Group. Hum. Mol. Genet. 7: 1229-1234 (1998). *
Hajeer AH, Hutchinson IV. TNF-alpha gene polymorphism: clinical and biological implications. Microsc. Res. Tech. 50: 216-228 (2000). *
Hajjaj-Hassouni N, Burgos-Vargas R. Ankylosing spondylitis and reactive arthritis in the developing world. Best Pract. Res. Clin. Rheumatol. 22: 709-723 (2008).
Hake SB, Masternak K, Kammerbauer C, Janzen C, Reith W, Steimle V. CIITA leucine-rich repeats control nuclear localization, in vivo recruitment to the major histocompatibility complex (MHC) class II enhanceosome, and MHC class II gene transactivation. Mol. Cell. Biol. 20: 7716-7725 (2000). *
Hakenberg J, Nussbaum AK, Schild H, Rammensee HG, Kuttler C, Holzhutter HG, Kloetzel PM, Kaufmann SH, Mollenkopf HJ. MAPPP: MHC class I antigenic peptide processing prediction. Appl. Bioinformatics 2: 155-158 (2003).
Hallett WH, Murphy WJ. Natural killer cells: biology and clinical use in cancer therapy. Cell. Mol. Immunol. 1: 12-21 (2004). *
Halling-Brown M, Quartey-Papafio R, Travers PJ, Moss DS. SiPep: a system for the prediction of tissue-specific minor histocompatibility antigens. Int. J. Immunogenet. 33: 289-295 (2006). *
Halling-Brown M, Sansom CE, Davies M, Titball RW, Moss DS. Are bacterial vaccine antigens T-cell epitope depleted? Trends Immunol. 29: 374-379 (2008). *
Hamada K, Gleason SL, Levi BZ, Hirschfeld S, Appella E, Ozato K. H-2RIIBP, a member of the nuclear hormone receptor superfamily that binds to both the regulatory element of major histocompatibility class I genes and the estrogen response element. Proc. Natl. Acad. Sci. U.S.A. 86: 8289-8293 (1989). *
Hamilton LJ, Dai Y, Jackson GD. Bile regulates the expression of major histocompatibility complex class II molecules on rat intestinal epithelium. Gastroenterology 113: 1901-1905 (1997). *
Hammer GE, Gonzalez F, James E, Nolla H, Shastri N. In the absence of aminopeptidase ERAAP, MHC class I molecules present many unstable and highly immunogenic peptides. Nat. Immunol. 8: 101-108 (2007). *
Hammer GE, Kanaseki T, Shastri N. The final touches make perfect the peptide-MHC class I repertoire. Immunity 26: 397-406 (2007). *
Hampton TH, Stanton BA. A novel approach to analyze gene expression data demonstrates that the DeltaF508 mutation in CFTR down regulates the antigen presentation pathway. Am. J. Physiol. Lung Cell. Mol. Physiol. Dec 31 [Epub ahead of print] (2009). *
Hamrah P, Dana MR. Corneal antigen-presenting cells. Chem. Immunol. Allergy 92: 58-70 (2007).
Han JF, Zhao TT, Liu HL, Lin ZH, Wang HM, Ruan ZH, Zou LY, Wu YZ. Identification of a new HLA-A*0201-restricted cytotoxic T lymphocyte epitope from CML28. Cancer Immunol. Immunother. 55: 1575-1583 (2006). *
Hanafusa T, Imagawa A. Insulitis in human type 1 diabetes. Ann. N. Y. Acad. Sci. 1150: 297-299 (2008). *
Hanauer SB. Update on the etiology, pathogenesis and diagnosis of ulcerative colitis. Nat. Clin. Pract. Gastroenterol. Hepatol. 1: 26-31 (2004). *
Hanauer SB. New biologicals for inflammatory bowel disease. Gastroenterology & Hepatology Annual Review Vol. 1, June 2006, p. 67-71 (2006). *
Hanchard N, Diakite M, Koch O, Keating B, Pinder M, Jallow M, Sisay-Joof F, Nijnik A, Wilson J, Udalova I, Kwiatkowski D, Rockett K. Implications of inter-population linkage disequilibrium patterns on the approach to a disease association study in the human MHC class III. Immunogenetics 58: 465-470 (2006). *
Hanchard N, Rockett K, Udalova I, Wilson J, Keating B, Koch O, Nijnik A, Diakite M, Herbert M, Kwiatkowski D. An investigation of transmission ratio distortion in the central region of the human MHC. Genes Immun. 7: 51-58 (2006). *
Handunnetthi L, Ramagopalan SV, Ebers GC, Knight JC. Regulation of major histocompatibility complex class II gene expression, genetic variation and disease. Genes Immun. Nov 5 [Epub ahead of print] (2009). *
Hanig J, Lutz MB. Suppression of mature dendritic cell function by regulatory T cells in vivo is abrogated by CD40 licensing. J. Immunol. 180: 1405-1413 (2008). *
Hannestad K, Scott H. The MHC haplotype H2b converts two pure nonlupus mouse strains to producers of antinuclear antibodies. J. Immunol. 183: 3542-3550 (2009).
Hansen JJ, Holt L, Sartor RB. Gene expression patterns in experimental colitis in IL-10-deficient mice. Inflamm. Bowel Dis. 15: 890-899 (2009). *
Hansen K, Ruttekolk IR, Glauner H, Becker F, Brock R, Hannus S. The in vitro biological activity of the HLA-DR-binding clinical IgG4 antibody 1D09C3 is a consequence of the disruption of cell aggregates and can be abrogated by Fab arm exchange. Mol. Immunol. 46: 3269-3277 (2009). *
Hansen TH, Bouvier M. MHC class I antigen presentation: learning from viral evasion strategies. Nat. Rev. Immunol. 9: 503-513 (2009). *
Hansen TH, Huang S, Arnold PL, Fremont DH. Patterns of nonclassical MHC antigen presentation. Nat. Immunol. 8: 563-568 (2007). *
Hansson AS, Johansson AC, Holmdahl R. Critical role of the major histocompatibility complex and IL-10 in matrilin-1-induced relapsing polychondritis in mice. Arthritis Res. Ther. 6: R484-R491 (2004). *
Hanvesakul R, Maillere B, Briggs D, Baker R, Larche M, Ball S. Indirect recognition of T-cell epitopes derived from the alpha3 and transmembrane domain of HLA-A2. Am. J. Transplant. 7: 1148-1157 (2007). *
Hanyecz A, Bardos T, Berlo SE, Buzas E, Nesterovitch AB, Mikecz K, Glant TT. Induction of arthritis in SCID mice by T cells specific for the "shared epitope" sequence in the G3 domain of human cartilage proteoglycan. Arthritis Rheum. 48: 2959-2973 (2003). *
Hao S, Bai O, Li F, Yuan J, Laferte S, Xiang J. Mature dendritic cells pulsed with exosomes stimulate efficient cytotoxic T-lymphocyte responses and antitumour immunity. Immunology 120: 90-102 (2007). *
Hao S, Yuan J, Xu S, Munegowda MA, Deng Y, Gordon J, Xing Z, Xiang J. Antigen specificity acquisition of adoptive CD4+ regulatory T cells via acquired peptide-MHC class I complexes. J. Immunol. 181: 2428-2437 (2008). *
Haque A, Hajiaghamohseni LM, Li P, Toomy K, Blum JS. Invariant chain modulates HLA class II protein recycling and peptide presentation in nonprofessional antigen presenting cells. Cell. Immunol. 249: 20-29 (2007). *
Haraldsen G, Sollid LM, Bakke O, Farstad IN, Kvale D, Molberg, Norstein J, Stang E, Brandtzaeg P. Major histocompatibility complex class II-dependent antigen presentation by human intestinal endothelial cells. Gastroenterology 114: 649-656 (1998). *
Harding A. Fine-tuning our defenses. The Scientist May, 2007 (http://www.the-scientist.com/2007/05/01/s56/1/) (2007).
Hardy PO, Diallo TO, Matte C, Descoteaux A. Roles of phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase in the regulation of protein kinase C-alpha activation in interferon-gamma-stimulated macrophages. Immunology 128: e652-e660 (2009).
Harnesk K, Swanberg M, Diez M, Olsson T, Piehl F, Lidman O. Differential nerve injury-induced expression of MHC class II in the mouse correlates to genetic variability in the type I promoter of C2ta. J. Neuroimmunol. 212: 44-52 (2009).
Harnesk K, Swanberg M, Ockinger J, Diez M, Lidman O, Wallstrom E, Lobell A, Olsson T, Piehl F. Vra4 congenic rats with allelic differences in the class II transactivator gene display altered susceptibility to experimental autoimmune encephalomyelitis. J. Immunol. 180: 3289-3296 (2008). *
Harney SM, Vilarino-Guell C, Adamopoulos IE, Sims AM, Lawrence RW, Cardon LR, Newton JL, Meisel C, Pointon JJ, Darke C, Athanasou N, Wordsworth BP, Brown MA. Fine mapping of the MHC class III region demonstrates association of AIF1 and rheumatoid arthritis. Rheumatology (Oxford) 47: 1761-1767 (2008). *
Harris J, Schwinn N, Mahoney JA, Lin HH, Shaw M, Howard CJ, da Silva RP, Gordon S. A vitellogenic-like carboxypeptidase expressed by human macrophages is localized in endoplasmic reticulum and membrane ruffles. Int. J. Exp. Pathol. 87: 29-39 (2006). *
Harrison P, Pointon JJ, Farrar C, Harin A, Wordsworth BP. MHC2TA promoter polymorphism (-168*G/A, rs3087456) is not associated with susceptibility to rheumatoid arthritis in British Caucasian rheumatoid arthritis patients. Rheumatology (Oxford) 46: 409-411 (2007). *
Harrold LR, Liu NY. Polyarteritis nodosa presenting as pancytopenia: case report and review of the literature. Rheumatol. Int. 28: 1049-1051 (2008). *
Harvima IT, Nilsson G, Suttle MM, Naukkarinen A. Is there a role for mast cells in psoriasis? Arch. Dermatol. Res. 300: 461-478 (2008). *
Haskins K. Pathogenic T-cell clones in autoimmune diabetes: more lessons from the NOD mouse. Adv. Immunol. 87: 123-162 (2005).
Hasko G, Deitch EA, Nemeth ZH, Kuhel DG, Szabo C. Inhibitors of ATP-binding cassette transporters suppress interleukin-12 p40 production and major histocompatibility complex II up-regulation in macrophages. J. Pharmacol. Exp. Ther. 301: 103-110 (2002). *
Hasko G, Szabo C, Nemeth ZH, Deitch EA. Sulphasalazine inhibits macrophage activation: inhibitory effects on inducible nitric oxide synthase expression, interleukin-12 production and major histocompatibility complex II expression. Immunology 103: 473-478 (2001). *
Hasler P. Biological therapies directed against cells in autoimmune disease. Springer Semin. Immunopathol. 27: 443-456 (2006). *
Hassan AB, Nikitina-Zake L, Padyukov L, Karlsson G, Gupta M, Lundberg IE, Sanjeevi CB. MICA4/HLA-DRB1*04/TNF1 haplotype is associated with mixed connective tissue disease in Swedish patients. Hum. Immunol. 64: 290-296 (2003).
Hassanain HH, Chon SY, Gupta SL. Differential regulation of human indoleamine 2,3-dioxygenase gene expression by interferons-gamma and -alpha. Analysis of the regulatory region of the gene and identification of an interferon-gamma-inducible DNA-binding factor. J. Biol. Chem. 268: 5077-5084 (1993). *
Hasselberg A, Schon K, Tarkowski A, Lycke N. Role of CTA1R7K-COL-DD as a novel therapeutic mucosal tolerance-inducing vector for treatment of collagen-induced arthritis. Arthritis Rheum. 60: 1672-1682 (2009). *
Hattotuwagama CK, Doytchinova IA, Flower DR. Toward the prediction of class I and II mouse major histocompatibility complex-peptide-binding affinity: in silico bioinformatic step-by-step guide using quantitative structure-activity relationships. Methods Mol. Biol. 409: 227-245 (2007).
Hattotuwagama CK, Toseland CP, Guan P, Taylor DJ, Hemsley SL, Doytchinova IA, Flower DR. Toward prediction of class II mouse major histocompatibility complex peptide binding affinity: in silico bioinformatic evaluation using partial least squares, a robust multivariate statistical technique. J. Chem. Inf. Model. 46: 1491-1502 (2006). *
Haug M, Schepp CP, Kalbacher H, Dannecker GE, Holzer U. 70-kDa heat shock proteins: specific interactions with HLA-DR molecules and their peptide fragments. Eur. J. Immunol. 37: 1053-1063 (2007). *
Hayakawa Y, Smyth MJ. Innate immune recognition and suppression of tumors. Adv. Cancer Res. 95: 293-322 (2006).
Hayashi A, Wakita H, Yoshikawa T, Nakanishi T, Tsutsumi Y, Mayumi T, Mukai Y, Yoshioka Y, Okada N, Nakagawa S. A strategy for efficient cross-presentation of CTL-epitope peptides leading to enhanced induction of in vivo tumor immunity. J. Control Release 117: 11-19 (2007).
Hayday A, Gibbons D. Brokering the peace: the origin of intestinal T cells. Mucosal Immunol. 1: 172-174 (2008). *
Hayman MW, van Beijnen MT, Stamp LK, Spellerberg MB, O'Donnell JL. Soluble human leukocyte antigen: a diagnostic indicator of rheumatoid arthritis? J. Immunol. Methods 315: 19-26 (2006). *
He C, Hamon S, Li D, Barral-Rodriguez S, Ott J; Diabetes Genetics Consortium. MHC fine mapping of human type 1 diabetes using the T1DGC data. Diabetes Obes. Metab. 11 Suppl. 1: 53-59 (2009). *
He F, Guo R, Du X, Lu ZS, Weng JY, Lin W. Inhibitory effects of anti-CII TA M1-RNA on IFN-gamma induced major histocompatibility complex class II antigens expression on cultured human chondrocytes. Transpl. Immunol. 17: 231-236 (2007).
He Y, Li S, Feng L, Cheng F, Ye Z, Li Y. Effect of cyclosporine on expression of MIC in human hepatocytes. Transplant. Proc. 38: 2231-2233 (2006). *
He Y, Wang HH, Wang M, Zhou Z, Zhai WJ, Huang Y, Jiang EL, Wang ZD, Zhou SY, Liu QG, Feng SZ, Han MZ. Role of alloreactive natural killer cell in mouse MHC haploidentical bone marrow transplantation. Zhonghua Xue Ye Xue Za Zhi 27: 82-86 (2006).
Healy LJ, Collins HL, Thompson SJ. Systemic administration of tolerogenic dendritic cells ameliorates murine inflammatory arthritis. Open Rheumatol. J. 2: 71-80 (2008). *
Hearn A, York IA, Rock KL. The specificity of trimming of MHC class I-presented peptides in the endoplasmic reticulum. J. Immunol. 183: 5526-5536 (2009).
Heath WR, Carbone FR. Cross-presentation in viral immunity and self-tolerance. Nat. Rev. Immunol. 1: 126-134 (2001). *
Hee Kim S, Bianco N, Menon R, Lechman ER, Shufesky WJ, Morelli AE, Robbins PD. Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive. Mol. Ther. 13: 289-300 (2006).
Hegde NR, Chevalier MS, Wisner TW, Denton MC, Shire K, Frappier L, Johnson DC. The role of BiP in ER-associated degradation of major histocompatibility complex class I heavy chain induced by cytomegalovirus proteins. J. Biol. Chem. 281: 20910-20919 (2006). *
Held W, Coudert JD, Zimmer J. The NK cell receptor repertoire: formation, adaptation and exploitation. Curr. Opin. Immunol. 15: 233-237 (2003).
Held W, Mariuzza RA. Cis interactions of immunoreceptors with MHC and non-MHC ligands. Nat. Rev. Immunol. 8: 269-278 (2008). *
Helliwell C. Immunology primer. Immunology news: a new type of T cell is discovered (http://www.acnr.co.uk/JF07/ACNR_JF07_immunology.pdf). ACNR 6: 8-9 (2007). *
Hellman P, Eriksson H. Early activation markers of human peripheral dendritic cells. Hum. Immunol. 68: 324-333 (2007).
Helms C, Saccone NL, Cao L, Daw JA, Cao K, Hsu TM, Taillon-Miller P, Duan S, Gordon D, Pierce B, Ott J, Rice J, Fernandez-Vina MA, Kwok PY, Menter A, Bowcock AM. Localization of PSORS1 to a haplotype block harboring HLA-C and distinct from corneodesmosin and HCR. Hum. Genet. 118: 466-476 (2005). *
Hemalatha V, Srikanth P, Mallika M. Superantigens - concepts, clinical disease and therapy. Indian J. Med. Microbiol. 22: 204-211 (2004).
Hemminki K, Bermejo JL, Hemminki K, Forsti A. Genetics of inflammatory bowel disease: population aspects. Gastroenterology 134: 2190-2191 (2008). *
Henderson KN, Reid HH, Borg NA, Broughton SE, Huyton T, Anderson RP, McCluskey J, Rossjohn J. The production and crystallization of the human leukocyte antigen class II molecules HLA-DQ2 and HLA-DQ8 complexed with deamidated gliadin peptides implicated in coeliac disease. Acta Crystallogr. Sect. F. Struct. Biol. Cryst. Commun. 63: 1021-1025 (2007). *
Henrickson SE, Mempel TR, Mazo IB, Liu B, Artyomov MN, Zheng H, Peixoto A, Flynn MP, Senman B, Junt T, Wong HC, Chakraborty AK, von Andrian UH. T cell sensing of antigen dose governs interactive behavior with dendritic cells and sets a threshold for T cell activation. Nat. Immunol. 9: 282-291 (2008). *
Henry CJ, Huang Y, Wynne AM, Godbout JP. Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1beta and anti-inflammatory IL-10 cytokines. Brain Behav. Immun. 23: 309-317 (2009).
Herait P, Tursz T, Guillard MY, Hanna K, Lipinski M, Micheau C, Sancho-Garnier H, Schwaab G, Cachin Y, Degos L, et al. HLA-A, -B, and -DR antigens in North African patients with nasopharyngeal carcinoma. Tissue Antigens 22: 335-341 (1983).
Herd KA, Mahalingam S, Mackay IM, Nissen M, Sloots TP, Tindle RW. Cytotoxic T-lymphocyte epitope vaccination protects against human metapneumovirus infection and disease in mice. J. Virol. 80: 2034-2044 (2006). *
Heresbach D, Ababou A, Bourienne A, Alizadeh M, Quelvennec E, Pagenault M, Dabadie A, Berre NH, Campion JP, Launois B, Gosselin M, Genetet B, Bretagne JF, Semana G. Polymorphism of the microsatellites and tumor necrosis factor genes in chronic inflammatory bowel diseases. Gastroenterol. Clin. Biol. 21: 555-561 (1997).
Heresbach D, Alizadeh M, Bretagne JF, Dabadie A, Colombel JF, Pagenault M, Heresbach-Le Berre N, Genetet B, Gosselin M, Semana G. TAP gene transporter polymorphism in inflammatory bowel diseases. Scand. J. Gastroenterol. 32: 1022-1027 (1997).
Heresbach D, Alizadeh M, Bretagne JF, Gautier A, Quillivic F, Lemarchand B, Gosselin M, Genetet B, Semana G. Investigation of the association of major histocompatibility complex genes, including HLA class I, class II and TAP genes, with clinical forms of Crohn's disease. Eur. J. Immunogenet. 23: 141-151 (1996).
Herget M, Oancea G, Schrodt S, Karas M, Tampe R, Abele R. Mechanism of substrate sensing and signal transmission within an ABC transporter: use of a Trojan horse strategy. J. Biol. Chem. 282: 3871-3880 (2007). *
Hermann E, Berthe A, Truyens C, Alonso-Vega C, Parrado R, Torrico F, Carlier Y, Braud VM. Killer cell immunoglobulin-like receptor expression induction on neonatal CD8(+) T cells in vitro and following congenital infection with Trypanosoma cruzi. Immunology 129: 418-426 (2010). *
Hermann E, Fleischer B, Meyer zum Buschenfelde KH. Bacteria-specific cytotoxic CD8+ T cells: a missing link in the pathogenesis of the HLA-B27-associated spondylarthropathies. Ann. Med. 26: 365-369 (1994).
Herr M, Dudbridge F, Zavattari P, Cucca F, Guja C, March R, Campbell RD, Barnett AH, Bain SC, Todd JA, Koeleman BP. Evaluation of fine mapping strategies for a multifactorial disease locus: systematic linkage and association analysis of IDDM1 in the HLA region on chromosome 6p21. Hum. Mol. Genet. 9: 1291-1301 (2000). *
Herrera BM, Cader MZ, Dyment DA, Bell JT, Ramagopalan SV, Lincoln MR, Orton S, Chao MJ, Sadovnick AD, Ebers GC. Follow-up investigation of 12 proposed linkage regions in multiple sclerosis. Genes Immun. 7: 366-371 (2006). *
Herrmann I, Kellert M, Schmidt H, Mildner A, Hanisch UK, Bruck W, Prinz M, Nau R. Streptococcus pneumoniae infection aggravates experimental autoimmune encephalomyelitis via Toll-like receptor 2. Infect. Immun. 74: 4841-4848 (2006). *
Hervas-Stubbs S, Majlessi L, Simsova M, Morova J, Rojas MJ, Nouze C, Brodin P, Sebo P, Leclerc C. High frequency of CD4+ T cells specific for the TB10.4 protein correlates with protection against Mycobacterium tuberculosis infection. Infect. Immun. 74: 3396-3407 (2006). *
Hervas-Stubbs S, Olivier A, Boisgerault F, Thieblemont N, Leclerc C. TLR3 ligand stimulates fully functional memory CD8+ T-cells in the absence of CD4+ T-cell help. Blood 109: 5318-5326 (2007). *
Herve M, Isnardi I, Ng YS, Bussel JB, Ochs HD, Cunningham-Rundles C, Meffre E. CD40 ligand and MHC class II expression are essential for human peripheral B cell tolerance. J. Exp. Med. 204: 1583-1593 (2007). *
Heslan JM, Renaudin K, Thebault P, Josien R, Cuturi MC, Chiffoleau E. New evidence for a role of allograft accommodation in long-term tolerance. Transplantation 82: 1185-1193 (2006).
Hess AD, Thoburn CJ. Immune tolerance to self-major histocompatability complex class II antigens after bone marrow transplantation: role of regulatory T cells. Biol. Blood Marrow Transplant. 12: 518-529 (2006).
Hess PR, Barnes C, Woolard MD, Johnson MD, Cullen JM, Collins EJ, Frelinger JA. Selective deletion of antigen-specific CD8+ T cells by MHC class I tetramers coupled to the type I ribosome-inactivating protein, saporin. Blood 109: 3300-3307 (2007). *
Heward JM, Allahabadia A, Sheppard MC, Barnett AH, Franklyn JA, Gough SC. Association of the large multifunctional proteasome (LMP2) gene with Graves' disease is a result of linkage disequilibrium with the HLA haplotype DRB1*0304-DQB1*02-DQA1*0501. Clin. Endocrinol. (Oxf.) 51: 115-118 (1999). *
Hewitt EW, Lehner PJ. The ABC-transporter signature motif is required for peptide translocation but not peptide binding by TAP. Eur. J. Immunol. 33: 422-427 (2003). *
Heyman M. Symposium on 'dietary influences on mucosal immunity'. How dietary antigens access the mucosal immune system. Proc. Nutr. Soc. 60: 419-426 (2001).
Hickford JG, Zhou H, Fang Q. Haplotype analysis of the DQA genes in sheep: evidence supporting recombination between the loci. J. Anim. Sci. 85: 577-582 (2007). *
Hida S, Nagi-Miura N, Adachi Y, Ohno N. F1 hybrid mice (BALB/cxDBA/1) are resistant to collagen-induced arthritis with beta-glucan as an adjuvant. Biol. Pharm. Bull. 29: 1300-1303 (2006). *
Hill JA, Bell DA, Brintnell W, Yue D, Wehrli B, Jevnikar AM, Lee DM, Hueber W, Robinson WH, Cairns E. Arthritis induced by posttranslationally modified (citrullinated) fibrinogen in DR4-IE transgenic mice. J. Exp. Med. 205: 967-979 (2008). *
Hill JA, Southwood S, Sette A, Jevnikar AM, Bell DA, Cairns E. Cutting edge: the conversion of arginine to citrulline allows for a high-affinity peptide interaction with the rheumatoid arthritis-associated HLA-DRB1*0401 MHC class II molecule. J. Immunol. 171: 538-541 (2003). *
Hillaire S, Boucher E, Calmus Y, Gane P, Ballet F, Franco D, Moukthar M, Poupon R. Effects of bile acids and cholestasis on major histocompatibility complex class I in human and rat hepatocytes. Gastroenterology 107: 781-788 (1994).
Hillen N, Stevanovic S. Contribution of mass spectrometry-based proteomics to immunology. Expert Rev. Proteomics 3: 653-664 (2006).
Hiraide A, Imazeki F, Yokosuka O, Kanda T, Kojima, H, Fukai K, Suzuki Y, Hata A, Saisho H. Fas polymorphisms influence susceptibility to autoimmune hepatitis. Am. J. Gastroenterol. 100: 1322-1329 (2005). *
Hirano F, Tanaka H, Makino I. Chenodeoxycholic acid-dependent induction of major histocompatibility complex class I mRNA expression in a human hepatoma cell line. Biochem. Biophys. Res. Commun. 195: 1408-1414 (1993). *
Hirano F, Tanaka H, Makino Y, Okamoto K, Inaba M, Miura T, Makino I. Regulation of the major histocompatibility complex class I mRNA expression by bile acids in cultured human hepatoma cells. Biochem. Biophys. Res. Commun. 208: 935-942 (1995). *
Hirano F, Tanaka H, Makino Y, Okamoto K, Makino I. Effects of ursodeoxycholic acid and chenodeoxycholic acid on major histocompatibility complex class I gene expression. J. Gastroenterol. 31: 55-60 (1996).
Hirata S, Matsuyoshi H, Fukuma D, Kurisaki A, Uemura Y, Nishimura Y, Senju S. Involvement of regulatory T cells in the experimental autoimmune encephalomyelitis-preventive effect of dendritic cells expressing myelin oligodendrocyte glycoprotein plus TRAIL. J. Immunol. 178: 918-925 (2007). *
Hiremath MM, Chen VS, Suzuki K, Ting JP, Matsushima GK. MHC class II exacerbates demyelination in vivo independently of T cells. J. Neuroimmunol. 203: 23-32 (2008).
Hiromine Y, Fujisawa T, Noso S, Babaya N, Kawabata Y, Ikegami H. Congenic mapping of the MHC-linked susceptibility to type 1 diabetes in the NOD mouse: at least two genes contribute to the Idd16 effect. Ann. N. Y. Acad. Sci. 1150: 90-92 (2008). *
Hirose S, Jiang Y, Nishimura H, Shirai T. Significance of MHC class II haplotypes and IgG Fc receptors in SLE. Springer Semin. Immunopathol. 28: 163-174 (2006). *
Hirota K, Hashimoto M, Yoshitomi H, Tanaka S, Nomura T, Yamaguchi T, Iwakura Y, Sakaguchi N, Sakaguchi S. T cell self-reactivity forms a cytokine milieu for spontaneous development of IL-17+ Th cells that cause autoimmune arthritis. J. Exp. Med. 204: 41-47 (2007). *
Hirschfield GM, Liu X, Xu C, Lu Y, Xie G, Lu Y, Gu X, Walker EJ, Jing K, Juran BD, Mason AL, Myers RP, Peltekian KM, Ghent CN, Coltescu C, Atkinson EJ, Heathcote EJ, Lazaridis KN, Amos CI, Siminovitch KA. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. N. Engl. J. Med. 360: 2544-2555 (2009). *
Hiss JA, Bredenbeck A, Losch FO, Wrede P, Walden P, Schneider G. Design of MHC I stabilizing peptides by agent-based exploration of sequence space. Protein Eng. Des. Sel. 20: 99-108 (2007). *
Hoare HL, Sullivan LC, Clements CS, Ely LK, Beddoe T, Henderson KN, Lin J, Reid HH, Brooks AG, Rossjohn J. Subtle changes in peptide conformation profoundly affect recognition of the non-classical MHC class I molecule HLA-E by the CD94-NKG2 natural killer cell receptors. J. Mol. Biol. 377: 1297-1303 (2008). *
Hoare HL, Sullivan LC, Pietra G, Clements CS, Lee EJ, Ely LK, Beddoe T, Falco M, Kjer-Nielsen L, Reid HH, McCluskey J, Moretta L, Rossjohn J, Brooks AG. Structural basis for a major histocompatibility complex class Ib-restricted T cell response. Nat. Immunol. 7: 256-264 (2006). *
Hodges A, Sharrocks K, Edelmann M, Baban D, Moris A, Schwartz O, Drakesmith H, Davies K, Kessler B, McMichael A, Simmons A. Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. Nat. Immunol. 8: 569-577 (2007). *
Hoer S, Smith L, Lehner PJ. MARCH-IX mediates ubiquitination and downregulation of ICAM-1. FEBS Lett. 581: 45-51 (2007). *
Hoerbelt R, Benjamin LC, Shoji T, Johnston DR, Muniappan A, Guenther DA, Allan JS, Houser SL, Madsen JC. Effects of tolerance induction on the actions of interferon-gamma on porcine cardiac allografts. Transplant. Proc. 38: 3196-3198 (2006). *
Hoffman RW, Maldonado ME. Immune pathogenesis of mixed connective tissue disease: a short analytical review. Clin. Immunol. 128: 8-17 (2008). *
Hoffmann R. The potential role of cytokines and T cells in alopecia areata. J. Investig. Dermatol. Symp. Proc. 4: 235-238 (1999). *
Hofmann S, Gluckmann M, Kausche S, Schmidt A, Corvey C, Lichtenfels R, Huber C, Albrecht C, Karas M, Herr W. Rapid and sensitive identification of major histocompatibility complex class-I associated tumor peptides by nanoLC MALDI MS/MS. Mol. Cell. Proteomics 4: 1888-1897 (2005). *
Hogg KG, Kumkate S, Mountford AP. IL-10 regulates early IL-12-mediated immune responses induced by the radiation-attenuated schistosome vaccine. Int. Immunol. 15: 1451-1459 (2003). *
Hohler T, Kruger A, Schneider PM, Schopf RE, Knop J, Rittner C, Meyer zum Buschenfelde KH, Marker-Hermann E. A TNF-alpha promoter polymorphism is associated with juvenile onset psoriasis and psoriatic arthritis. J. Invest. Dermatol. 109: 562-565 (1997). *
Hohler T, Stradmann-Bellinghausen B, Starke R, Sanger R, Victor A, Rittner C, Schneider PM. C4A deficiency and nonresponse to hepatitis B vaccination. J. Hepatol. 37: 387-392 (2002). *
Hokama A, Mizoguchi E, Sugimoto K, Shimomura Y, Tanaka Y, Yoshida M, Rietdijk ST, De Jong YP, Snapper SB, Terhorst C, Blumberg RS, Mizoguchi A. Induced reactivity of intestinal CD4(+) T cells with an epithelial cell lectin, galectin-4, contributes to exacerbation of intestinal inflammation. Immunity 20: 681-693 (2004). *
Holling TM, Bergevoet MW, Wierda RJ, van Eggermond MC, van den Elsen PJ. Genetic and epigenetic control of the major histocompatibility complex class Ib gene HLA-G in trophoblast cell lines. Ann. N. Y. Acad. Sci. 1173: 538-544 (2009). *
Holling TM, van Eggermond MC, Jager MJ, van den Elsen PJ. Epigenetic silencing of MHC2TA transcription in cancer. Biochem. Pharmacol. 72: 1570-1576 (2006). *
Holm L, Bockermann R, Wellner E, Backlund J, Holmdahl R, Kihlberg J. Side-chain and backbone amide bond requirements for glycopeptide stimulation of T-cells obtained in a mouse model for rheumatoid arthritis. Bioorg. Med. Chem. 14: 5921-5932 (2006). *
Holm L, Frech K, Dzhambazov B, Holmdahl R, Kihlberg J, Linusson A. Quantitative structure-activity relationship of peptides binding to the class II major histocompatibility complex molecule A(q) associated with autoimmune arthritis. J. Med. Chem. 50: 2049-2059 (2007). *
Holm SJ, Sakuraba K, Mallbris L, Wolk K, Stahle M, Sanchez FO. Distinct HLA-C/KIR genotype profile associates with guttate psoriasis. J. Invest. Dermatol. 125: 721-730 (2005). *
Holm SJ, Sanchez F, Carlen LM, Mallbris L, Stahle M, O'Brien KP. HLA-Cw*0602 associates more strongly to psoriasis in the Swedish population than variants of the novel 6p21.3 gene PSORS1C3. Acta Derm. Venereol. 85: 2-8 (2005).
Holmberg D, Cilio CM, Lundholm M, Motta V. CTLA-4 (CD152) and its involvement in autoimmune disease. Autoimmunity 38: 225-233 (2005).
Holmberg J, Tuncel J, Yamada H, Lu S, Olofsson P, Holmdahl R. Pristane, a non-antigenic adjuvant, induces MHC class II-restricted, arthritogenic T cells in the rat. J. Immunol. 176: 1172-1179 (2006). *
Holmdahl R. Dissection of the genetic complexity of arthritis using animal models. Immunol. Lett. 103: 86-91 (2006).
Holmdahl R. Primer: comparative genetics of animal models of arthritis - a tool to resolve complexity. Nat. Clin. Pract. Rheumatol. 3: 104-111 (2007). *
Holmen C, Elsheikh E, Christensson M, Liu J, Johansson AS, Qureshi AR, Jalkanen S, Sumitran-Holgersson S. Anti endothelial cell autoantibodies selectively activate SAPK/JNK signalling in Wegener's granulomatosis. J. Am. Soc. Nephrol. 18: 2497-2508 (2007). *
Holmes S, Siebold C, Jones EY, Friese MA, Fugger L, Bell J. Multiple sclerosis: MHC associations and therapeutic implications. Expert Rev. Mol. Med. 7: 1-17 (2005).
Holoshitz J. The rheumatoid arthritis HLA-DRB1 shared epitope. Curr. Opin. Rheumatol. Jan 7 [Epub ahead of print] (2010).
Holtappels R, Gillert-Marien D, Thomas D, Podlech J, Deegen P, Herter S, Oehrlein-Karpi SA, Strand D, Wagner M, Reddehase MJ. Cytomegalovirus encodes a positive regulator of antigen presentation. J. Virol. 80: 7613-7624 (2006). *
Homo-Delarche F, Calderari S, Irminger JC, Gangnerau MN, Coulaud J, Rickenbach K, Dolz M, Halban P, Portha B, Serradas P. Islet inflammation and fibrosis in a spontaneous model of type 2 diabetes, the GK rat. Diabetes 55: 1625-1633 (2006). *
Honey K, Rudensky AY. Lysosomal cysteine proteases regulate antigen presentation. Nat. Rev. Immunol. 3: 472-482 (2003).
Hong SY, Kim TG, Kwon TH, Jang YS, Yang MS. Production of an anti-mouse MHC class II monoclonal antibody with biological activity in transgenic tobacco. Protein Expr. Purif. 54: 134-138 (2007). *
Hoof I, Peters B, Sidney J, Pedersen LE, Sette A, Lund O, Buus S, Nielsen M. NetMHCpan, a method for MHC class I binding prediction beyond humans. Immunogenetics 61: 1-13 (2009). *
Hopkins LM, Davis JM, Buchli R, Vangundy RS, Schwartz KA, Gerlach JA. MHC class I-associated peptides identified from normal platelets and from individuals with idiopathic thrombocytopenic purpura. Hum. Immunol. 66: 874-883 (2005).
Hopkins PA, Fraser JD, Pridmore AC, Russell HH, Read RC, Sriskandan S. Superantigen recognition by HLA class II on monocytes up-regulates Toll-like receptor 4 and enhances proinflammatory responses to endotoxin. Blood 105: 3655-3662 (2005). *
Hopkins TA, Sugden MC, Holness MJ, Kozak R, Dyck JR, Lopaschuk GD. Control of cardiac pyruvate dehydrogenase activity in peroxisome proliferator-activated receptor-alpha transgenic mice. Am. J. Physiol. Heart Circ. Physiol. 285: H270-H276 (2003). *
Hopner S, Dickhaut K, Hofstatter M, Kramer H, Ruckerl D, Soderhall JA, Gupta S, Marin-Esteban V, Kuhne R, Freund C, Jung G, Falk K, Rotzschke O. Small organic compounds enhance antigen-loading of class II MHC proteins by targeting the polymorphic P1 pocket. J. Biol. Chem. 281: 38535-38542 (2006). *
Horibe EK, Sacks J, Unadkat J, Raimondi G, Wang Z, Ikeguchi R, Marsteller D, Ferreira LM, Thomson AW, Lee WP, Feili-Hariri M. Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion. Transpl. Immunol. 18: 307-318 (2008).
Horn GT, Bugawan TL, Long CM, Erlich HA. Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc. Natl. Acad. Sci. U.S.A. 85: 6012-6016 (1988). *
Hornquist CE, Lu X, Rogers-Fani PM, Rudolph U, Shappell S, Birnbaumer L, Harriman GR. G(alpha)i2-deficient mice with colitis exhibit a local increase in memory CD4+ T cells and proinflammatory Th1-type cytokines. J. Immunol. 158: 1068-1077 (1997).
Horowitz A, Li X, Poles MA, Tsuji M. Use of immobilized HLA-A2:Ig dimeric proteins to determine the level of epitope-specific, HLA-restricted CD8(+) T-cell response. Scand. J. Immunol. 70: 415-422 (2009). *
Horton R, Gibson R, Coggill P, Miretti M, Allcock RJ, Almeida J, Forbes S, Gilbert JG, Halls K, Harrow JL, Hart E, Howe K, Jackson DK, Palmer S, Roberts AN, Sims S, Stewart CA, Traherne JA, Trevanion S, Wilming L, et al. Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project. Immunogenetics 60: 1-18 (2008). *
Horton R, Wilming L, Rand V, Lovering RC, Bruford EA, Khodiyar VK, Lush MJ, Povey S, Talbot CC, Wright MW, Wain HM, Trowsdale J, Ziegler A, Beck S. Gene map of the extended human MHC. Nat. Rev. Genet. 5: 889-899 (2004). *
Horwitz MS, Efrat S, Christen U, von Herrath MG, Oldstone MB. Adenovirus E3 MHC inhibitory genes but not TNF/Fas apoptotic inhibitory genes expressed in beta cells prevent autoimmune diabetes. Proc. Natl. Acad. Sci. U.S.A. 106: 19450-19454 (2009). *
Hosseini BH, Louban I, Djandji D, Wabnitz GH, Deeg J, Bulbuc N, Samstag Y, Gunzer M, Spatz JP, Hammerling GJ. Immune synapse formation determines interaction forces between T cells and antigen-presenting cells measured by atomic force microscopy. Proc. Natl. Acad. Sci. U.S.A. 106: 17852-17857 (2009). *
Houston EG Jr, Fink PJ. MHC drives TCR repertoire shaping, but not maturation, in recent thymic emigrants. J. Immunol. 183: 7244-7249 (2009).
Houtchens KA, Nichols RJ, Ladner MB, Boal HE, Sollars C, Geraghty DE, Davis LM, Parham P, Trachtenberg EA. High-throughput killer cell immunoglobulin-like receptor genotyping by MALDI-TOF mass spectrometry with discovery of novel alleles. Immunogenetics 59: 525-537 (2007). *
Hovhannisyan Z, Weiss A, Martin A, Wiesner M, Tollefsen S, Yoshida K, Ciszewski C, Curran SA, Murray JA, David CS, Sollid LM, Koning F, Teyton L, Jabri B. The role of HLA-DQ8 beta57 polymorphism in the anti-gluten T-cell response in coeliac disease. Nature 456: 534-538 (2008). *
Howard LM, Kohm AP, Castaneda CL, Miller SD. Therapeutic blockade of TCR signal transduction and co-stimulation in autoimmune disease. Curr. Drug Targets Inflamm. Allergy 4: 205-216 (2005).
Howcroft TK, Weissman JD, Gegonne A, Singer DS. A T lymphocyte-specific transcription complex containing RUNX1 activates MHC class I expression. J. Immunol. 174: 2106-2115 (2005). *
Howson JM, Walker NM, Clayton D, Todd JA; Diabetes Genetics Consortium. Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. Diabetes Obes. Metab. 11 Suppl. 1: 31-45 (2009). *
Howson JM, Walker NM, Smyth DJ, Todd JA. Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families. Genes Immun. 10: S74-S84 (2009).
Hreha G, Jefferson DM, Yu CH, Grubman SA, Alsabeh R, Geller SA, Vierling JM. Immortalized intrahepatic mouse biliary epithelial cells: immunologic characterization and immunogenicity. Hepatology 30: 358-371 (1999). *
Hsieh CC, Lin BF. The effects of vitamin E supplementation on autoimmune-prone New Zealand blackxNew Zealand white F1 mice fed an oxidised oil diet. Br. J. Nutr. 93: 655-662 (2005). *
Hsu PN, Wolf Bryant P, Sutkowski N, McLellan B, Ploegh HL, Huber BT. Association of mouse mammary tumor virus superantigen with MHC class II during biosynthesis. J. Immunol. 166: 3309-3314 (2001). *
Hu CM, Lin HH, Chiang MT, Chang PF, Chau LY. Systemic expression of heme oxygenase-1 ameliorates type 1 diabetes in NOD mice. Diabetes 56: 1240-1247 (2007). *
Hu W, Blazar BR, Manivel JC, Paradis K, Sharp HL. Phenotypical and functional characterization of intrahepatic bile duct cells from common duct ligated mice. J. Lab. Clin. Med. 128: 536-544 (1996).
Huan J, Kaler LJ, Mooney JL, Subramanian S, Hopke C, Vandenbark AA, Rosloniec EF, Burrows GG, Offner H. MHC class II derived recombinant T cell receptor ligands protect DBA/1LacJ mice from collagen-induced arthritis. J. Immunol. 180: 1249-1257 (2008). *
Huang D, Liu L, Noren K, Xia SQ, Trifunovic J, Pirskanen R, Lefvert AK. Genetic association of Ctla-4 to myasthenia gravis with thymoma. J. Neuroimmunol. 88: 192-198 (1998).
Huang D, Pirskanen R, Hjelmstrom P, Lefvert AK. Polymorphisms in IL-1beta and IL-1 receptor antagonist genes are associated with myasthenia gravis. J. Neuroimmunol. 81: 76-81 (1998).
Huang D, Xia S, Zhou Y, Pirskanen R, Liu L, Lefvert AK. No evidence for interleukin-4 gene conferring susceptibility to myasthenia gravis. J. Neuroimmunol. 92: 208-211 (1998).
Huang F, Kitaura Y, Jang I, Naramura M, Kole HH, Liu L, Qin H, Schlissel MS, Gu H. Establishment of the major compatibility complex-dependent development of CD4(+) and CD8(+) T cells by the Cbl family proteins. Immunity 25: 571-581 (2006). *
Huang H, Hao S, Li F, Ye Z, Yang J, Xiang J. CD4+ Th1 cells promote CD8+ Tc1 cell survival, memory response, tumor localization and therapy by targeted delivery of interleukin 2 via acquired pMHC I complexes. Immunology 120: 148-159 (2007). *
Huang J, Goedert JJ, Sundberg EJ, Cung TD, Burke PS, Martin MP, Preiss L, Lifson J, Lichterfeld M, Carrington M, Yu XG. HLA-B*35-Px-mediated acceleration of HIV-1 infection by increased inhibitory immunoregulatory impulses. J. Exp. Med. 206: 2959-2966 (2009). *
Huang J, Zhang X, Zhang M, Zhu JD, Zhang YL, Lin Y, Wang KS, Qi XF, Zhang Q, Liu GZ, Yu J, Cui Y, Yang PY, Wang ZQ, Han ZG. Up-regulation of DLK1 as an imprinted gene could contribute to human hepatocellular carcinoma. Carcinogenesis 28: 1094-1103 (2007). *
Huang L, Koziel MJ. Immunology of hepatitis C virus infection. Curr. Opin. Gastroenterol. 16: 558-564 (2000).
Huang W, Connor E, Rosa TD, Muir A, Schatz D, Silverstein J, Crockett S, She JX, Maclaren NK. Although DR3-DQB1*0201 may be associated with multiple component diseases of the autoimmune polyglandular syndromes, the human leukocyte antigen DR4-DQB1*0302 haplotype is implicated only in beta-cell autoimmunity. J. Clin. Endocrinol. Metab. 81: 2559-2563 (1996). *
Huang XS, Zhao SP, Hu M, Luo YP. Apolipoprotein M likely extends its anti-atherogenesis via anti-inflammation. Med. Hypotheses 69: 136-140 (2007).
Huard B. Expression of inhibitory receptors for MHC class I molecules on T cells. Crit. Rev. Immunol. 20: 471-476 (2000).
Huber BT, Beutner U, Subramanyam M. The role of superantigens in the immunobiology of retroviruses. Ciba Found. Symp. 187: 132-140 (1994).
Hubert FX, Kinkel SA, Webster KE, Cannon P, Crewther PE, Proeitto AI, Wu L, Heath WR, Scott HS. A specific anti-AIRE antibody reveals AIRE expression is restricted to medullary thymic epithelial cells and not expressed in periphery. J. Immunol. 180: 3824-3832 (2008). *
Hueber AJ, Matzkies FG, Rahmeh M, Manger B, Kalden JR, Nagel T. CTLA-4 lacking the cytoplasmic domain costimulates IL-2 production in T-cell hybridomas. Immunol. Cell Biol. 84: 51-58 (2006). *
Hughes AL. Evolution of the ATP-binding-cassette transmembrane transporters of vertebrates. Mol. Biol. Evol. 11: 899-910 (1994). *
Hughes AM, Jokinen P, Bannasch DL, Lohi H, Oberbauer AM. Association of a dog leukocyte antigen class II haplotype with hypoadrenocorticism in Nova Scotia duck tolling retrievers. Tissue Antigens Jan 28 [Epub ahead of print] (2010). *
Hughes AR, Brothers CH, Mosteller M, Spreen WR, Burns DK. Genetic association studies to detect adverse drug reactions: abacavir hypersensitivity as an example. Pharmacogenomics 10: 225-233 (2009).
Hughes CR, Miles S, Walbroehl JM. Support for the minimal essential MHC hypothesis: a parrot with a single, highly polymorphic MHC class II B gene. Immunogenetics 60: 219-231 (2008). *
Hughes EH, Collins RW, Kondeatis E, Wallace GR, Graham EM, Vaughan RW, Stanford MR. Associations of major histocompatibility complex class I chain-related molecule polymorphisms with Behcet's disease in Caucasian patients. Tissue Antigens 66: 195-199 (2005). *
Hughes S, Hughes A, Brothers C, Spreen W, Thorborn D; on behalf of the CNA106030 Study Team. PREDICT-1 (CNA106030): the first powered, prospective trial of pharmacogenetic screening to reduce drug adverse events. Pharm. Stat. 7: 121-129 (2007).
Hugot JP, Laurent-Puig P, Gower-Rousseau C, Caillat-Zucman S, Beaugerie L, Dupas JL, Van Gossum A, Bonait-Pellie C, Cortot A, Thomas G. Linkage analyses of chromosome 6 loci, including HLA, in familial aggregations of Crohn disease. G.E.T.A.I.D. Am. J. Med. Genet. 52: 207-213 (1994).
Hui J, Oka A, Tamiya G, Tomizawa M, Kulski JK, Penhale WJ, Tay GK, Iizuka M, Ozawa A, Inoko H. Corneodesmosin DNA polymorphisms in MHC haplotypes and Japanese patients with psoriasis. Tissue Antigens 60: 77-83 (2002). *
Hui J, Palmer LJ, James AL, Musk AW, Beilby JP. AluyMICB dimorphism within the class I region of the major histocompatibility complex is associated with asthma and airflow obstruction in the Busselton population. Clin. Exp. Allergy 36: 728-734 (2006). *
Hulsmeyer M, Welfle K, Pohlmann T, Misselwitz R, Alexiev U, Welfle H, Saenger W, Uchanska-Ziegler B, Ziegler A. Thermodynamic and structural equivalence of two HLA-B27 subtypes complexed with a self-peptide. J. Mol. Biol. 346: 1367-1379 (2005). *
Hultqvist M, Backlund J, Bauer K, Gelderman KA, Holmdahl R. Lack of reactive oxygen species breaks T cell tolerance to collagen type II and allows development of arthritis in mice. J. Immunol. 179: 1431-1437 (2007). *
Humar A, Kumar D, Gray M, Moussa G, Venkataraman S, Kumar R, Tipples GA. A prospective assessment of cytomegalovirus immune evasion gene transcription profiles in transplant patients with cytomegalovirus infection. Transplantation 83: 1200-1206 (2007).
Hummell DS. The role of T-cell receptors in health and disease. Compr. Ther. 20: 616-622 (1994).
Humphray SJ, Oliver K, Hunt AR, Plumb RW, Loveland JE, Howe KL, Andrews TD, Searle S, Hunt SE, Scott CE, Jones MC, Ainscough R, Almeida JP, Ambrose KD, Ashwell RI, Babbage AK, Babbage S, Bagguley CL, Bailey J, Banerjee R, Barker DJ, et al. DNA sequence and analysis of human chromosome 9. Nature 429: 369-374 (2004). *
Hundemer M, Schmidt S, Condomines M, Lupu A, Hose D, Moos M, Cremer F, Kleist C, Terness P, Belle S, Ho AD, Goldschmidt H, Klein B, Christensen O. Identification of a new HLA-A2-restricted T-cell epitope within HM1.24 as immunotherapy target for multiple myeloma. Exp. Hematol. 34: 486-496 (2006). *
Hundorfean G, Zimmer KP, Strobel S, Gebert A, Ludwig D, Buening J. Luminal antigens access late endosomes of intestinal epithelial cells enriched in MHC I and MHC II molecules - in vivo study in Crohn's ileitis. Am. J. Physiol. Gastrointest. Liver Physiol. 293: G798-G808 (2007). *
Hung SI, Chung WH, Jee SH, Chen WC, Chang YT, Lee WR, Hu SL, Wu MT, Chen GS, Wong TW, Hsiao PF, Chen WH, Shih HY, Fang WH, Wei CY, Lou YH, Huang YL, Lin JJ, Chen YT. Genetic susceptibility to carbamazepine-induced cutaneous adverse drug reactions. Pharmacogenet. Genomics 16: 297-306 (2006).
Hung SI, Chung WH, Liou LB, Chu CC, Lin M, Huang HP, Lin YL, Lan JL, Yang LC, Hong HS, Chen MJ, Lai PC, Wu MS, Chu CY, Wang KH, Chen CH, Fann CS, Wu JY, Chen YT. HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol. Proc. Natl. Acad. Sci. U.S.A. 102: 4134-4139 (2005). *
Hunt PJ, Marshall SE, Weetman AP, Bunce M, Bell JI, Wass JA, Welsh KI. Histocompatibility leucocyte antigens and closely linked immunomodulatory genes in autoimmune thyroid disease. Clin. Endocrinol. (Oxf.) 55: 491-499 (2001). *
Hunziker L, Recher M, Macpherson AJ, Ciurea A, Freigang S, Hengartner H, Zinkernagel RM. Hypergammaglobulinemia and autoantibody induction mechanisms in viral infections. Nat. Immunol. 4: 343-349 (2003). *
Husain S, Yildirim-Toruner C, Rubio JP, Field J; The Southern MS Genetics Consortium, Schwalb M, Cook S, Devoto M, Vitale E. Variants of ST8SIA1 are associated with risk of developing multiple sclerosis. PLoS ONE 3: e2653 (2008). *
Husain Z, Kelly MA, Eisenbarth GS, Pugliese A, Awdeh ZL, Larsen CE, Alper CA. The MHC type 1 diabetes susceptibility gene is centromeric to HLA-DQB1. J. Autoimmun. 30: 266-272 (2008).
Huseby ES, Crawford F, White J, Marrack P, Kappler JW. Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide. Nat. Immunol. 7: 1191-1199 (2006). *
Husebye E, Lovas K. Pathogenesis of primary adrenal insufficiency. Best Pract. Res. Clin. Endocrinol. Metab. 23: 147-157 (2009).
Husebye ES, Bratland E, Bredholt G, Fridkin M, Dayan M, Mozes E. The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. Endocrinology 147: 2411-2416 (2006). *
Hussain S. Role of surfactant protein A in the innate host defense and autoimmunity. Autoimmunity 37: 125-130 (2004).
Hussain SF, Yang D, Suki D, Grimm E, Heimberger AB. Innate immune functions of microglia isolated from human glioma patients. J. Transl. Med. 4: 15 (2006). *
Hviid TV. HLA-G in human reproduction: aspects of genetics, function and pregnancy complications. Hum. Reprod. Update 12: 209-232 (2006).
Hviid TV. Non-classical HLA genes: from implantation to transplantation. Ugeskr. Laeger. 168: 461-466 (2006).
Hviid TV, Christiansen OB. Linkage disequilibrium between human leukocyte antigen (HLA) class II and HLA-G - possible implications for human reproduction and autoimmune disease. Hum. Immunol. 66: 688-699 (2005).
Hviid TV, Milman N, Hylenius S, Jakobsen K, Jensen MS, Larsen LG. HLA-G polymorphisms and HLA-G expression in sarcoidosis. Sarcoidosis Vasc. Diffuse Lung Dis. 23: 30-37 (2006).
Hwang SA, Actor JK. Lactoferrin modulation of BCG-infected dendritic cell functions. Int. Immunol. 21: 1185-1197 (2009).
Hyer RN, Julier C, Buckley JD, Trucco M, Rotter J, Spielman R, Barnett A, Bain S, Boitard C, Deschamps I, et al. High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q. Am. J. Hum. Genet. 48: 243-257 (1991). *
Iacono OL, Petta S, Venezia G, Di Marco V, Tarantino G, Barbaria F, Mineo C, De Lisi S, Almasio PL , Craxi A. Anti-tissue transglutaminase antibodies in patients with abnormal liver tests: is it always coeliac disease? Am. J. Gastroenterol. 100: 2472-2477 (2005). *
Iannuzzi MC. Thomas A. Neff lecture. Advances in the genetics of sarcoidosis. Proc. Am. Thorac. Soc. 4: 457-460 (2007). *
Ibnou-Zekri N, Iwamoto M, Fossati L, McConahey PJ, Izui S. Role of the major histocompatibility complex class II Ea gene in lupus susceptibility in mice. Proc. Natl. Acad. Sci. U.S.A. 94: 14654-14659 (1997). *
Ibrahim SM, Gold R. Genomics, proteomics, metabolomics: what is in a word for multiple sclerosis? Curr. Opin. Neurol. 18: 231-235 (2005).
Ichiki Y, Bowlus CL, Shimoda S, Ishibashi H, Vierling JM, Gershwin ME. T cell immunity and graft-versus-host disease (GVHD). Autoimmun. Rev. 5: 1-9 (2006).
Ide A, Babu SR, Robles DT, Wang T, Erlich HA, Bugawan TL, Rewers M, Fain PR, Eisenbarth GS. Homozygosity for premature stop codon of the MHC class I chain-related gene A (MIC-A) is associated with early activation of islet autoimmunity of DR3/4-DQ2/8 high risk DAISY relatives. J. Clin. Immunol. 25: 303-308 (2005). *
Ide M, Dittmar M, Wurm M, Kanitz M, Kahaly GJ. Polymorphisms of MICA microsatellites in thyroidal autoimmunity. Med. Klin. (Munich) 102: 11-15 (2007).
Iezzi G, Boni A, Degl'innocenti E, Grioni M, Bertilaccio MT, Bellone M. Type 2 cytotoxic T lymphocytes modulate the activity of dendritic cells toward type 2 immune responses. J. Immunol. 177: 2131-2137 (2006). *
Igyarto BZ, Jenison MC, Dudda JC, Roers A, Muller W, Koni PA, Campbell DJ, Shlomchik MJ, Kaplan DH. Langerhans cells suppress contact hypersensitivity responses via cognate CD4 interaction and Langerhans cell-derived IL-10. J. Immunol. 183: 5085-5093 (2009).
Iikuni N, Ikari K, Momohara S, Tomatsu T, Hara M, Yamanaka H, Okamoto H, Kamatani N. MHC2TA is associated with rheumatoid arthritis in Japanese patients. Ann. Rheum. Dis. 66: 274-275 (2007). *
Ikarashi Y, Kawai K, Watanabe H, Matsumoto Y, Omata S, Fujiwara M. Immunosuppressive activity of macrophages in mice undergoing graft-versus-host reaction due to major histocompatibility complex class I plus II difference. Immunology 79: 95-102 (1993). *
Ikarashi Y, Matsumoto Y, Omata S, Fujiwara M. Recipient-derived T cells participate in autoimmune-like hepatic lesions induced by graft-versus-host reaction. Autoimmunity 20: 121-127 (1995).
Ikegami H, Fujisawa T, Makino S, Ogihara T. Genetic dissection of type 1 diabetes susceptibility gene, Idd3, by ancestral haplotype congenic mapping. Ann. N. Y. Acad. Sci. 958: 325-328 (2002). *
Ikehara S. The future of stem cell transplantation in autoimmune disease. Clin. Rev. Allergy Immunol. Jul 16 [Epub ahead of print] (2009). *
Ikehara S. Bone marrow transplantation for autoimmune diseases. Acta Haematol. 99: 116-132 (1998).
Ikehara S. Bone marrow transplantation: a new strategy for intractable diseases. Drugs Today (Barc.) 38: 103-111 (2002).
Iking-Konert C, Vogl T, Prior B, Wagner C, Sander O, Bleck E, Ostendorf B, Schneider M, Andrassy K, Hansch GM. T lymphocytes in patients with primary vasculitis: expansion of CD8+ T cells with the propensity to activate polymorphonuclear neutrophils. Rheumatology (Oxford) 47: 609-616 (2008). *
Ikuta Y, Hayashida Y, Hirata S, Irie A, Senju S, Kubo T, Nakatsura T, Monji M, Sasaki Y, Baba H, Nishimura Y. Identification of the H2-Kd-restricted cytotoxic T lymphocyte epitopes of a tumor-associated antigen, SPARC, which can stimulate antitumor immunity without causing autoimmune disease in mice. Cancer Sci. 100: 132-137 (2009). *
Iliopoulou BP, Alroy J, Huber BT. Persistent arthritis in Borrelia burgdorferi-infected HLA-DR4-positive CD28-negative mice post-antibiotic treatment. Arthritis Rheum. 58: 3892-3901 (2008). *
Iliopoulou BP, Guerau-De-Arellano M, Huber BT. HLA-DR alleles determine responsiveness to Borrelia burgdorferi antigens in a mouse model of self-perpetuating arthritis. Arthritis Rheum. 60: 3831-3840 (2009). *
Illoh K, Campbell C, Illoh O, Diehl J, Cherry J, Elkhaloun A, Chen Y, Hallenbeck J. Mucosal tolerance to E-selectin and response to systemic inflammation. J. Cereb. Blood Flow Metab. 26: 1538-1550 (2006).
Imanishi T, Kamigaki T, Nakamura T, Hayashi S, Yasuda T, Kawasaki K, Takase S, Ajiki T, Kuroda Y. Correlation between expression of major histocompatibility complex class I and that of antigen presenting machineries in carcinoma cell lines of the pancreas, biliary tract and colon. Kobe J. Med. Sci. 52: 85-95 (2006). *
Innes GK, Nagafuchi Y, Fuller BJ, Hobbs KE. Increased expression of major histocompatibility antigens in the liver as a result of cholestasis. Transplantation 45: 749-752 (1988).
Inohara N, Nunez G. NODs: intracellular proteins involved in inflammation and apoptosis. Nat. Rev. Immunol. 3: 371-382 (2003). *
Inoue S, Popp FC, Koehl GE, Piso P, Schlitt HJ, Geissler EK, Dahlke MH. Immunomodulatory effects of mesenchymal stem cells in a rat organ transplant model. Transplantation 81: 1589-1595 (2006).
Inozume T, Hanada K, Wang QJ, Yang JC. IL-17 secreted by tumor reactive T cells induces IL-8 release by human renal cancer cells. J. Immunother. 32: 109-117 (2009).
Insaidoo FK, Zajicek J, Baker BM. A general and efficient approach for NMR studies of peptide dynamics in class I MHC peptide binding grooves. Biochemistry 48: 9708-9710 (2009). *
International MHC and Autoimmunity Genetics Network (IMAGEN), Rioux JD, Goyette P, Vyse TJ, Hammarstrom L, Fernando MM, Green T, De Jager PL, Foisy S, Wang J, de Bakker PI, Leslie S, McVean G, Padyukov L, Alfredsson L, Annese V, Hafler DA, et al. Mapping of multiple susceptibility variants within the MHC region for 7 immune-mediated diseases. Proc. Natl. Acad. Sci. U.S.A. 106: 18680-18685 (2009). *
International Psoriasis Genetics Consortium. The International Psoriasis Genetics Study: assessing linkage to 14 candidate susceptibility loci in a cohort of 942 affected sib pairs. Am. J. Hum. Genet. 73: 430-437 (2003). *
Invernizzi P, Gershwin ME. The genetic basis of primary biliary cirrhosis: premises, not promises. Gastroenterology 135: 1044-1047 (2008). *
Ip CW, Kroner A, Bendszus M, Leder C, Kobsar I, Fischer S, Wiendl H, Nave KA, Martini R. Immune cells contribute to myelin degeneration and axonopathic changes in mice overexpressing proteolipid protein in oligodendrocytes. J. Neurosci. 26: 8206-8216 (2006). *
Ireland J, Herzog J, Unanue ER. Cutting edge: unique T cells that recognize citrullinated peptides are a feature of protein immunization. J. Immunol. 177: 1421-1425 (2006). *
Irie J, Wu Y, Kachapati K, Mittler RS, Ridgway WM. Modulating protective and pathogenic CD4+ subsets via CD137 in type 1 diabetes. Diabetes 56:186-196 (2007). *
Irla M, Hollander G, Reith W. Control of central self-tolerance induction by autoreactive CD4(+) thymocytes. Trends Immunol. 31: 71-79 (2010). *
Irla M, Hugues S, Gill J, Nitta T, Hikosaka Y, Williams IR, Hubert FX, Scott HS, Takahama Y, Hollander GA, Reith W. Autoantigen-specific interactions with CD4(+) thymocytes control mature medullary thymic epithelial cell cellularity. Immunity 29: 451-463 (2008). *
Irons R, Fritsche KL. n-3 PUFA fail to affect in vivo, antigen-driven CD8(+)T-cell proliferation in the spleen of naive mice. Br. J. Nutr. 95: 838-844 (2006). *
Irony-Tur-Sinai M, Grigoriadis N, Lourbopoulos A, Pinto-Maaravi F, Abramsky O, Brenner T. Amelioration of autoimmune neuroinflammation by recombinant human alpha-fetoprotein. Exp. Neurol. 198: 136-144 (2006).
Iruretagoyena MI, Sepulveda SE, Lezana JP, Hermoso M, Bronfman M, Gutierrez MA, Jacobelli SH, Kalergis AM. Inhibition of NF-kappaB enhances the capacity of immature dendritic cells to induce antigen-specific tolerance in experimental autoimmune encephalomyelitis. J. Pharmacol. Exp. Ther. 318: 59-67 (2006). *
Ishido S, Goto E, Matsuki Y, Ohmura-Hoshino M. E3 ubiquitin ligases for MHC molecules. Curr. Opin. Immunol. 21: 78-83 (2009).
Ishihara M, Ohno S. Genetic influences on sarcoidosis. Eye 11: 155-161 (1997).
Ishihara M, Ohno S, Mizuki N, Yamagata N, Ishida T, Naruse T, Ando A, Inoko H. LMP7 polymorphism in Japanese patients with sarcoidosis and Behcet's disease. Hum. Immunol. 51: 103-105 (1996).
Ishihara M, Ohno S, Mizuki N, Yamagata N, Ishida T, Naruse T, Kuwata S, Inoko H. Genetic polymorphisms of the major histocompatibility complex-encoded antigen-processing genes TAP and LMP in sarcoidosis. Hum. Immunol. 45: 105-110 (1996).
Ishihara M, Yamagata N, Ohno S, Naruse T, Ando A, Kawata H, Ozawa A, Ohkido M, Mizuki N, Shiina T, Ando H, Inoko H. Genetic polymorphisms in the keratin-like S gene within the human major histocompatibility complex and association analysis on the susceptibility to psoriasis vulgaris. Tissue Antigens 48: 182-186 (1996).
Ishikawa H, Ito S, Nishio N, Yuzawa Y, Matsuo SI, Isobe KI. Injection of bleomycin in newborn mice induces autoimmune sialitis that is transferred by CD4 T cells. Immunol. Cell Biol. 87: 351-358 (2009). *
Ishiwata K, Watanabe N, Guo M, Tomihara K, Brumlik MJ, Yagita H, Pardoll D, Chen L, Shin T. Costimulator B7-DC attenuates strong Th2 responses induced by Nippostrongylus brasiliensis. J. Immunol. Jan 11 [Epub ahead of print] (2010).
Ishiyama K, Ohdan H, Tokita D, Shishida M, Tanaka Y, Irei T, Asahara T. Induction of endotoxin tolerance inhibits alloimmune responses. Transpl. Immunol. 16: 158-165 (2006).
Ishizuka J, Grebe K, Shenderov E, Peters B, Chen Q, Peng Y, Wang L, Dong T, Pasquetto V, Oseroff C, Sidney J, Hickman H, Cerundolo V, Sette A, Bennink JR, McMchael A, Yewdell JW. Quantitating T cell cross-reactivity for unrelated peptide antigens. J. Immunol. 183: 4337-4345 (2009).
Ito T, Ito N, Saatoff M, Hashizume H, Fukamizu H, Nickoloff BJ, Takigawa M, Paus R. Maintenance of hair follicle immune privilege is linked to prevention of NK cell attack. J. Invest. Dermatol. 128: 1196-1206 (2008). *
Ito T, Meyer KC, Ito N, Paus R. Immune privilege and the skin. Curr. Dir. Autoimmun. 10: 27-52 (2008).
Itoh K, Yamada A. Personalized peptide vaccines: a new therapeutic modality for cancer. Cancer Sci. 97: 970-976 (2006). *
Itoh S, Matsuzaki Y, Kimura T, Ikegami T, Shoda J, Fujiwara M, Tanaka N. Cytokine profile of liver-infiltrating CD4+ T cells separated from murine primary biliary cirrhosis-like hepatic lesions induced by graft-versus-host reaction. J. Gastroenterol. Hepatol. 15: 443-451 (2000). *
Ittiprasert W, Kantachuvesiri S, Pavasuthipaisit K, Verasertniyom O, Chaomthum L, Totemchokchyakarn K, Kitiyanant Y. Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations. J. Autoimmun. 25: 77-84 (2005).
Ivansson EL, Magnusson JJ, Magnusson PK, Erlich HA, Gyllensten UB. MHC loci affecting cervical cancer risk: distinguishing the effects of HLA-DQB1 and non-HLA genes TNF, LTA, TAP1 and TAP2. Genes Immun. 9: 613-623 (2008).
Iwamura C, Nakayama T. Toll-like receptors in the respiratory system: their roles in inflammation. Curr. Allergy Asthma Rep. 8: 7-13 (2008).
Iwanami K, Matsumoto I, Tanaka Y, Inoue A, Goto D, Ito S, Tsutsumi A, Sumida T. Arthritogenic T cell epitope in glucose-6-phosphate isomerase (GPI)-induced arthritis. Arthritis Res. Ther. 10: R130 (2008). *
Jabri B, Ebert E. Human CD8 intraepithelial lymphocytes: a unique model to study the regulation of effector cytotoxic T lymphocytes in tissue. Immunol. Rev. 215: 202-214 (2007). *
Jackson R, McNicol AM, Farquharson M, Foulis AK. Class II MHC expression in normal adrenal cortex and cortical cells in autoimmune Addison's disease. J. Pathol. 155: 113-120 (1988).
Jacob JB, Kong YC, Meroueh C, Snower DP, David CS, Ho YS, Wei WZ. Control of her-2 tumor immunity and thyroid autoimmunity by MHC and regulatory T cells. Cancer Res. 67: 7020-7027 (2007). *
Jacobs JP, Wu HJ, Benoist C, Mathis D. IL-17-producing T cells can augment autoantibody-induced arthritis. Proc. Natl. Acad. Sci. U.S.A. Dec 2 [Epub ahead of print] (2009). *
Jacobson EM, Tomer Y. The CD40, CTLA-4, thyroglobulin, TSH receptor, and PTPN22 gene quintet and its contribution to thyroid autoimmunity: back to the future. J. Autoimmun. 28: 85-98 (2007).
Jacobson EM, Yang H, Menconi F, Wang R, Osman R, Skrabanek L, Li CW, Fadlalla M, Gandhi A, Chaturvedi V, Smith EP, Schwemberger S, Osterburg A, Babcock GF, Tomer Y. Employing a recombinant HLA-DR3 expression system to dissect major histocompatibility complex II- thyroglobulin peptide dynamism: a genetic, biochemical, and reverse immunological perspective. J. Biol. Chem. 284: 34231-34243 (2009). *
Jaen O, Rulle S, Bessis N, Zago A, Boissier MC, Falgarone G. Dendritic cells modulated by innate immunity improve collagen-induced arthritis and induce regulatory T cells in vivo. Immunology 126: 35-44 (2009). *
Jager E, Karbach J, Gnjatic S, Jager D, Maeurer M, Atmaca A, Arand M, Skipper J, Stockert E, Chen YT, Old LJ, Knuth A. Identification of a naturally processed NY-ESO-1 peptide recognized by CD8+ T cells in the context of HLA-B51. Cancer Immun. 2: 12 (2002). *
Jager E, Salter R, Castelli C, Hohn H, Freitag K, Karbach J, Neukirch C, Necker A, Knuth A, Maeurer MJ. Impact of antigen presentation on TCR modulation and cytokine release: implications for detection and sorting of antigen-specific CD8+ T cells using HLA-A2 wild-type or HLA-A2 mutant tetrameric complexes. J. Immunol. 168: 2766-2772 (2002). *
Jager MD, Liu JY, Timrott KF, Popp FC, Stoeltzing O, Lang SA, Piso P, Geissler EK, Schlitt HJ, Dahlke MH. Sirolimus promotes tolerance for donor and recipient antigens after MHC class II disparate bone marrow transplantation in rats. Exp. Hematol. 35: 164-170 (2007). *
Jagiello P, Gencik M, Arning L, Wieczorek S, Kunstmann E, Csernok E, Gross WL, Epplen JT. New genomic region for Wegener's granulomatosis as revealed by an extended association screen with 202 apoptosis-related genes. Hum. Genet. 114: 468-477 (2004). *
Jahromi MM, Eisenbarth GS. Genetic determinants of type 1 diabetes across populations. Ann. N. Y. Acad. Sci. 1079: 289-299 (2006). *
Jahromi MM, Eisenbarth GS. Cellular and molecular pathogenesis of type 1A diabetes. Cell. Mol. Life Sci. 64: 865-872 (2007). *
Jahromi MM, Millward BA, Demaine AG. Significant correlation between association of polymorphism in codon 10 of the transforming growth factor-beta1 T (29) C with type 1 diabetes and patients with nephropathy disorder. J. Interferon Cytokine Res. Dec 29 [Epub ahead of print] (2009).
Jain A, Sharma MC, Sarkar C, Bhatia R, Singh S, Handa R. Increased expression of cell adhesion molecules in inflammatory myopathies: diagnostic utility and pathogenetic insights. Folia. Neuropathol. 47: 33-42 (2009).
Jalleh RP, Gilbertson JA, Williamson RC, Slater SD, Foster CS. Expression of major histocompatibility antigens in human chronic pancreatitis. Gut 34: 1452-1457 (1993). *
James EA, Kwok WW, Ettinger RA, Thompson AR, Pratt KP. T-cell responses over time in a mild hemophilia A inhibitor subject: epitope identification and transient immunogenicity of the corresponding self-peptide. J. Thromb. Haemost. 5: 2399-2407 (2007). *
James EA, Moustakas AK, Bui J, Nouv R, Papadopoulos GK, Kwok WW. The binding of antigenic peptides to HLA-DR is influenced by interactions between pocket 6 and pocket 9. J. Immunol. 183: 3249-3258 (2009).
James I, McKinnon E, Gaudieri S, Morahan G; Diabetes Genetics Consortium. Missingness in the T1DGC MHC fine-mapping SNP data: association with HLA genotype and potential influence on genetic association studies. Diabetes Obes. Metab. 11 Suppl. 1: 101-107 (2009). *
Jarchum I, Dilorenzo TP. Ins2 deficiency augments spontaneous HLA-A*0201-restricted T cell responses to insulin. J. Immunol. 184: 658-665 (2010).
Jawaheer D, Li W, Graham RR, Chen W, Damle A, Xiao X, Monteiro J, Khalili H, Lee A, Lundsten R, Begovich A, Bugawan T, Erlich H, Elder JT, Criswell LA, Seldin MF, Amos CI, Behrens TW, Gregersen PK. Dissecting the genetic complexity of the association between human leukocyte antigens and rheumatoid arthritis. Am. J. Hum. Genet. 71: 585-594 (2002). *
Jean S, Quelvennec E, Alizadeh M, Guggenbuhl P, Birebent B, Perdriger A, Grosbois B, Pawlotsky PY, Semana G. DRB1*15 and DRB1*03 extended haplotype interaction in primary Sjogren's syndrome genetic susceptibility. Clin. Exp. Rheumatol. 16: 725-728 (1998).
Jenkins MK, Khoruts A, Ingulli E, Mueller DL, McSorley SJ, Reinhardt RL, Itano A, Pape KA. In vivo activation of antigen-specific CD4 T cells. Annu. Rev. Immunol. 19: 23-45 (2001). *
Jenkinson SR, Intlekofer AM, Sun G, Feigenbaum L, Reiner SL, Bosselut R. Expression of the transcription factor cKrox in peripheral CD8 T cells reveals substantial postthymic plasticity in CD4-CD8 lineage differentiation. J. Exp. Med. 204: 267-272 (2007). *
Jensen KD, Su X, Shin S, Li L, Youssef S, Yamasaki S, Steinman L, Saito T, Locksley RM, Davis MM, Baumgarth N, Chien YH. Thymic selection determines gammadelta T cell effector fate: antigen-naive cells make interleukin-17 and antigen-experienced cells make interferon gamma. Immunity 29: 90-100 (2008). *
Jensen PE. Recent advances in antigen processing and presentation. Nat. Immunol. 8: 1041-1048 (2007). *
Jensen PE, Weber DA, Thayer WP, Chen X, Dao CT. HLA-DM and the MHC class II antigen presentation pathway. Immunol. Res. 20: 195-205 (1999).
Jia J, Cui J, Liu X, Han J, Yang S, Wei Y, Chen Y. Genome-scale search of tumor-specific antigens by collective analysis of mutations, expressions and T-cell recognition. Mol. Immunol. 46: 1824-1829 (2009). *
Jia QT, Xu LH, Zha QB, Chi XY, Li FY, He XH. High level expression of HLA-A*0203-BSP fusion protein in Escherichia coli and construction of soluble HLA-A*0203 monomer and tetramer loaded with Epstein-Barr virus peptide. Cell. Mol. Immunol. 4: 301-308 (2007). *
Jiang F, Yoshida T, Nakaki F, Terawaki S, Chikuma S, Kato Y, Okazaki IM, Honjo T, Okazaki T. Identification of QTLs that modify peripheral neuropathy in NOD.H2b-Pdcd1-/- mice. Int. Immunol. 21: 499-509 (2009).
Jiang G, Ke Y, Sun D, Han G, Kaplan HJ, Shao H. Reactivation of uveitogenic T cells by retinal astrocytes derived from experimental autoimmune uveitis-prone B10RIII mice. Invest. Ophthalmol. Vis. Sci. 49: 282-289 (2008). *
Jiang G, Ke Y, Sun D, Wang Y, Kaplan HJ, Shao H. Regulatory role of TLR ligands on the activation of autoreactive T cells by retinal astrocytes. Invest. Ophthalmol. Vis. Sci. 50: 4769-4776 (2009).
Jiang H, Chess L. Chapter 2. How the immune system achieves self-nonself discrimination during adaptive immunity. Adv. Immunol. 102: 95-133 (2009).
Jiang W, Anderson MS, Bronson R, Mathis D, Benoist C. Modifier loci condition autoimmunity provoked by Aire deficiency. J. Exp. Med. 202: 805-815 (2005). *
Jiang X, Fares MA. Identifying coevolutionary patterns in human leukocyte antigen (HLA) molecules. Evolution Nov 20 [Epub ahead of print] (2009). *
Jiang X, Shen C, Yu H, Karunakaran KP, Brunham RC. Differences in innate immune responses correlate with differences in murine susceptibility to Chlamydia muridarum pulmonary infection. Immunology Sep 11 [Epub ahead of print] (2009). *
Jie HB, Sarvetnick N. The role of NK cells and NK cell receptors in autoimmune disease. Autoimmunity 37: 147-153 (2004).
Jimenez BD, Maldonado L, Dahl RH, Quattrochi LC, Guzelian PS. Ectopic expression of MHC class II genes (RT1.B(I) beta/alpha) in rat hepatocytes in vivo and in culture can be elicited by treatment with the pregnane X receptor agonists pregnenolone 16 alpha-carbonitrile and dexamethasone. Life Sci. 71: 311-323 (2002). *
Jin JO, Park HY, Xu Q, Park JI, Zvyagintseva T, Stonik VA, Kwak JY. Ligand of scavenger receptor class-A indirectly induces maturation of human blood dendritic cells via production of tumor necrosis factor-alpha. Blood 113: 5839-5847 (2009). *
Jin Y, Shen L, Chong EM, Hamrah P, Zhang Q, Chen L, Dana MR. The chemokine receptor CCR7 mediates corneal antigen-presenting cell trafficking. Mol. Vis. 13: 626-634 (2007). *
Jinushi M, Hodi FS, Dranoff G. Therapy-induced antibodies to MHC class I chain-related protein A antagonize immune suppression and stimulate antitumor cytotoxicity. Proc. Natl. Acad. Sci. U.S.A. 103: 9190-9195 (2007). *
Jinushi M, Takehara T, Tatsumi T, Hiramatsu N, Sakamori R, Yamaguchi S, Hayashi N. Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas. J. Hepatol. 43: 1013-1020 (2005). *
Jinushi M, Takehara T, Tatsumi T, Kanto T, Groh V, Spies T, Kimura R, Miyagi T, Mochizuki K, Sasaki Y, Hayashi N. Expression and role of MICA and MICB in human hepatocellular carcinomas and their regulation by retinoic acid. Int. J. Cancer 104: 354-361 (2003). *
Jinushi M, Vanneman M, Munshi NC, Tai YT, Prabhala RH, Ritz J, Neuberg D, Anderson KC, Carrasco DR, Dranoff G. MHC class I chain-related protein A antibodies and shedding are associated with the progression of multiple myeloma. Proc. Natl. Acad. Sci. U.S.A. 105: 1285-1290 (2008). *
Jirholt J, Cook A, Emahazion T, Sundvall M, Jansson L, Nordquist N, Pettersson U, Holmdahl R. Genetic linkage analysis of collagen-induced arthritis in the mouse. Eur. J. Immunol. 28: 3321-3328 (1998). *
Johansson S, Lie BA, Cambon-Thomsen A, Pociot F, Nerup J, Kockum I, Thorsby E, Undlien DE. No evidence of type 1 diabetes susceptibility genes in the region centromeric of the HLA complex. Hum. Immunol. 64: 951-959 (2003).
Johnnidis JB, Venanzi ES, Taxman DJ, Ting JP, Benoist CO, Mathis DJ. Chromosomal clustering of genes controlled by the aire transcription factor. Proc. Natl. Acad. Sci. U.S.A. 102: 7233-7238 (2005). *
Johnson AD, O'Donnell CJ. An open access database of genome-wide association results. BMC Med. Genet. 10: 6 (2009). *
Johnson BA, Wang J, Taylor EM, Caillier SJ, Herbert J, Khan OA, Cross AH, De Jager PL, Gourraud PA, Cree BC, Hauser SL, Oksenberg JR. Multiple sclerosis susceptibility alleles in African Americans. Genes Immun. Oct 29 [Epub ahead of print] (2009).
Johnson CM, Traherne JA, Jamieson SE, Tremelling M, Bingham S, Parkes M, Blackwell JM, Trowsdale J. Analysis of the BTNL2 truncating splice site mutation in tuberculosis, leprosy and Crohn's disease. Tissue Antigens 69: 236-241 (2007). *
Johnson HM, Torres BA, Soos JM. Superantigens: structure and relevance to human disease. Proc. Soc. Exp. Biol. Med. 212: 99-109 (1996).
Johnson ML, Keeton LG, Zhu ZB, Volanakis JE, Cooper MD, Schroeder HW Jr. Age-related changes in serum immunoglobulins in patients with familial IgA deficiency and common variable immunodeficiency (CVID). Clin. Exp. Immunol. 108: 477-483 (1997). *
Johnson RW, Tew MB, Arnett FC. The genetics of systemic sclerosis. Curr. Rheumatol. Rep. 4: 99-10 (2002).
Johnston DT, Schroeder HW Jr. B-cell numbers in the blood of patients with non-HLA*B8 or non-HLA*B44 common variable immunodeficiency. Ann. Allergy Asthma Immunol. 98: 163-167 (2007).
Jones AL, Mowry BJ, Pender MP, Greer JM. Immune dysregulation and self-reactivity in schizophrenia: do some cases of schizophrenia have an autoimmune basis? Immunol. Cell. Biol. 83: 9-17 (2005). *
Jones DB, Coulson AF, Duff GW. Sequence homologies between hsp60 and autoantigens. Immunol. Today 14: 115-118 (1993).
Jones EY, Fugger L, Strominger JL, Siebold C. MHC class II proteins and disease: a structural perspective. Nat. Rev. Immunol. 6: 271-282 (2006). *
Jones LL, Brophy SE, Bankovich AJ, Colf LA, Hanick NA, Garcia KC, Kranz DM. Engineering and characterization of a stabilized alpha 1/alpha 2 module of the class I major histocompatibility complex product Ld. J. Biol. Chem. 281: 25734-25744 (2006). *
Jones MA, Hislop AD, Snaith JS. Synthesis and biological evaluation of two chemically modified peptide epitopes for the class I MHC protein HLA-B*2705. Org. Biomol. Chem. 4: 3769-3777 (2006). *
Jones MA, Notta JK, Cobbold M, Palendira M, Hislop AD, Wilkie J, Snaith JS. Synthesis and ex vivo profiling of chemically modified cytomegalovirus CMVpp65 epitopes. J. Pept. Sci. 14: 313-320 (2008).
Joplin R. Infectious etiology of primary biliary cirrhosis? Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper�s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 19-20. October 15-16 (2003). *
Joplin RE, Neuberger JM. Immunopathology of primary biliary cirrhosis. Eur. J. Gastroenterol. Hepatol. 11: 587-593 (1999).
Jordanova ES, Gorter A, Ayachi O, Prins F, Durrant LG, Kenter GG, van der Burg SH, Fleuren GJ. Human leukocyte antigen class I, MHC class I chain-related molecule A, and CD8+/regulatory T-cell ratio: which variable determines survival of cervical cancer patients? Clin. Cancer Res. 14: 2028-2035 (2008). *
Jubala CM, Lamerato-Kozicki AR, Borakove M, Lang J, Gardner LA, Coffey D, Helm KM, Schaack J, Baier M, Cutter GR, Bellgrau D, Modiano JF. MHC-dependent desensitization of intrinsic anti-self reactivity. Cancer Immunol. Immunother. 58: 171-185 (2009).
Jumnainsong A, Jearanaikoon P, Khahmahpahte S, Wongsena W, Romphruk AV, Chumworathayi B, Vaeteewoottacharn K, Ponglikitmongkol M, Romphruk A, Leelayuwat C. Associations of MICB with cervical cancer in north-eastern Thais: identification of major histocompatibility complex class I chain-related gene B motifs influencing natural killer cell activation. Clin. Exp. Immunol. 153: 205-213 (2008). *
Jumnainsong A, Romphruk AV, Jearanaikoon P, Klumkrathok K, Romphruk A, Luanrattanakorn S, Leelayuwat C. Association of polymorphic extracellular domains of MICA with cervical cancer in northeastern Thai population. Tissue Antigens 69: 326-333 (2007). *
Junevik K, Werlenius O, Hasselblom S, Jacobsson S, Nilsson-Ehle H, Andersson PO. The expression of NK cell inhibitory receptors on cytotoxic T cells in B-cell chronic lymphocytic leukaemia (B-CLL). Ann. Hematol. 86: 89-94 (2007). *
Jung YO, Min SY, Cho ML, Park MJ, Jeon JY, Lee JS, Oh HJ, Kang CM, Park HS, Park KS, Cho SG, Park SH, Kim HY. CD8alpha+ dendritic cells enhance the antigen-specific CD4+ T-cell response and accelerate development of collagen-induced arthritis. Immunol. Lett. 111: 76-83 (2007).
Jurisic V, Stojacic-Djenic S, Colovic N, Konjevic G. The role of cytokine in regulation of the natural killer cell activity. Srp. Arh. Celok. Lek. 136: 423-429 (2008).
Justesen S, Harndahl M, Lamberth K, Nielsen LL, Buus S. Functional recombinant MHC class II molecules and high-throughput peptide-binding assays. Immunome Res. 5: 2 (2009). *
Jutras I, Desjardins M. Phagocytosis: at the crossroads of innate and adaptive immunity. Annu. Rev. Cell Dev. Biol. 21: 511-527 (2005). *
Kabelitz D, Holtmeier W. gammadelta T cells link innate and adaptive immune responses. Chem. Immunol. Allergy 86: 151-183 (2005).
Kageyama G, Kawano S, Kanagawa S, Kondo S, Sugita M, Nakanishi T, Shimizu A, Kumagai S. Effect of mutated transporters associated with antigen-processing 2 on characteristic major histocompatibility complex binding peptides: analysis using electrospray ionization tandem mass spectrometry. Rapid Commun. Mass Spectrom. 18: 995-1000 (2004). *
Kagnoff MF. Coeliac disease: genetic, immunological and environmental factors in disease pathogenesis. Scand. J. Gastroenterol. Suppl. 114: 45-54 (1985).
Kahan BD. Forty years of publication of Transplantation Proceedings - the first decade: the flowering of immunology and immunogenetics. Transplant. Proc. 41: 5-10 (2009). *
Kahles H, Kordonouri O, Ramos Lopez E, Walter M, Rosinger S, Boehm BO, Badenhoop K, Seidl C, Ziegler A; Diabetes Genetics Consortium. Mating in parents of type 1 diabetes families as a function of the HLA DR-DQ haplotype. Diabetes Obes. Metab. 11 Suppl. 1: 84-87 (2009). *
Kahraman A, Schlattjan M, Kocabayoglu P, Yildiz-Meziletoglu S, Schlensak M, Fingas CD, Wedemeyer I, Marquitan G, Gieseler RK, Baba HA, Gerken G, Canbay A. Major histocompatibility complex class I-related chains A and B (MIC A/B): a novel role in nonalcoholic steatohepatitis. Hepatology 51: 92-102 (2010). *
Kai H, Shibuya K, Wang Y, Kameta H, Kameyama T, Tahara-Hanaoka S, Miyamoto A, Honda S, Matsumoto I, Koyama A, Sumida T, Shibuya A. Critical role of M. tuberculosis for dendritic cell maturation to induce collagen-induced arthritis in H-2b background of C57BL/6 mice. Immunology 118: 233-239 (2006). *
Kaila B, Grant D, Pettigrew N, Greenberg H, Bernstein CN. Crohn's disease recurrence in a small bowel transplant. Am. J. Gastroenterol. 99: 158-162 (2004). *
Kaiser BK, Pizarro JC, Kerns J, Strong RK. Structural basis for NKG2A/CD94 recognition of HLA-E. Proc. Natl. Acad. Sci. U.S.A. 105: 6696-6701 (2008). *
Kaiser BK, Yim D, Chow IT, Gonzalez S, Dai Z, Mann HH, Strong RK, Groh V, Spies T. Disulphide-isomerase-enabled shedding of tumour-associated NKG2D ligands. Nature 447: 482-487 (2007). *
Kaka AS, Foster AE, Weiss HL, Rooney CM, Leen AM. Using dendritic cell maturation and IL-12 producing capacity as markers of function: a cautionary tale. J. Immunother. 31: 359-369 (2008).
Kakimi K, Guidotti LG, Koezuka Y, Chisari FV. Natural killer T cell activation inhibits hepatitis B virus replication in vivo. J. Exp. Med. 192: 921-930 (2000). *
Kalli KR, Krco CJ, Hartmann LC, Goodman K, Maurer MJ, Yu C, Johnson EM, Erskine CL, Disis ML, Wettstein PJ, Fikes JD, Beebe M, Ishioka G, Knutson KL. An HLA-DR-degenerate epitope pool detects insulin-like growth factor binding protein 2-specific immunity in patients with cancer. Cancer Res. 68: 4893-4901 (2008). *
Kalman B, Lublin FD. The genetics of multiple sclerosis. A review. Biomed. Pharmacother. 53: 358-370 (1999).
Kaluza W, Reuss E, Grossmann S, Hug R, Schopf RE, Galle PR, Maerker-Hermann E, Hoehler T. Different transcriptional activity and in vitro TNF-alpha production in psoriasis patients carrying the TNF-alpha 238A promoter polymorphism. J. Invest. Dermatol. 114: 1180-1183 (2000). *
Kambayashi T, Allenspach EJ, Chang JT, Zou T, Shoag JE, Reiner SL, Caton AJ, Koretzky GA. Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation. J. Immunol. 182: 4686-4695 (2009).
Kambhu S, Falldorf P, Lee JS. Endogenous retroviral long terminal repeats within the HLA-DQ locus. Proc. Natl. Acad. Sci. U.S.A. 87: 4927-4931 (1990). *
Kamda JD, Singer SM. Phosphoinositide 3-kinase dependent inhibition of dendritic cell IL-12 production by Giardia lamblia. Infect. Immun. 77: 685-693 (2009). *
Kameda H, Pandey JP, Kaburaki J, Inoko H, Kuwana M. Immunoglobulin allotype gene polymorphisms in systemic sclerosis: interactive effect of MHC class II and KM genes on anticentromere antibody production. Ann. Rheum. Dis. 57: 366-370 (1998). *
Kamiguchi K, Torigoe T, Fujiwara O, Ohshima S, Hirohashi Y, Sahara H, Hirai I, Kohgo Y, Sato N. Disruption of the association of 73 kDa heat shock cognate protein with transporters associated with antigen processing (TAP) decreases TAP-dependent translocation of antigenic peptides into the endoplasmic reticulum. Microbiol. Immunol. 52: 94-106 (2008). *
Kamiya S, Owaki T, Morishima N, Fukai F, Mizuguchi J, Yoshimoto T. An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells. J. Immunol. 173: 3871-3877 (2004). *
Kammoun-Krichen M, Bougacha-Elleuch N, Rebai A, Mnif M, Abid M, Ayadi H. TNF gene polymorphisms in Graves' disease: TNF-308 A/G meta-analysis. Ann. Hum. Biol. 35: 656-661 (2008).
Kamon H, Kawabe T, Kitamura H, Lee J, Kamimura D, Kaisho T, Akira S, Iwamatsu A, Koga H, Murakami M, Hirano T. TRIF-GEFH1-RhoB pathway is involved in MHCII expression on dendritic cells that is critical for CD4 T-cell activation. EMBO J. 25: 4108-4119 (2006). *
Kamphuis S, Hrafnkelsdottir K, Klein MR, de Jager W, Haverkamp MH, van Bilsen JH, Albani S, Kuis W, Wauben MH, Prakken BJ. Novel self-epitopes derived from aggrecan, fibrillin and matrix-metalloproteinase 3 drive distinct autoreactive T cell responses in juvenile idiopathic arthritis and in health. Arthritis Res. Ther. 8: R178 (2006). *
Kamphuis S, Kuis W, de Jager W, Teklenburg G, Massa M, Gordon G, Boerhof M, Rijkers GT, Uiterwaal CS, Otten HG, Sette A, Albani S, Prakken BJ. Tolerogenic immune responses to novel T-cell epitopes from heat-shock protein 60 in juvenile idiopathic arthritis. Lancet 366: 50-56 (2005). *
Kamradt T, Volkmer-Engert R. Cross-reactivity of T lymphocytes in infection and autoimmunity. Mol. Divers. 8: 271-280 (2004).
Kanaseki T, Blanchard N, Hammer GE, Gonzalez F, Shastri N. ERAAP synergizes with MHC class I molecules to make the final cut in the antigenic peptide precursors in the endoplasmic reticulum. Immunity 25: 795-806 (2006). *
Kanazawa S, Ota S, Sekine C, Tada T, Otsuka T, Okamoto T, Sonderstrup G, Peterlin BM. Aberrant MHC class II expression in mouse joints leads to arthritis with extraarticular manifestations similar to rheumatoid arthritis. Proc. Natl. Acad. Sci. U.S.A. 103: 14465-14470 (2006). *
Kane KP, Silver ET, Hazes B. Specificity and function of activating Ly-49 receptors. Immunol. Rev. 181: 104-114 (2001). *
Kaneko M, Akiyama Y, Takimoto H, Kumazawa Y. Mechanism of up-regulation of immunoglobulin A production in the intestine of mice unresponsive to lipopolysaccharide. Immunology 116: 64-70 (2005). *
Kaneoka H, Naito S. Superantigens and autoimmune diseases. Nippon Rinsho 55: 1363-1369 (1997).
Kang Y, Xu L, Wang B, Chen A, Zheng G. Cutting edge: immunosuppressant as adjuvant for tolerogenic immunization. J. Immunol. 180: 5172-5176 (2008). *
Kanterakis S, Magira E, Rosenman KD, Rossman M, Talsania K, Monos DS. SKDM human leukocyte antigen (HLA) tool: a comprehensive HLA and disease associations analysis software. Hum. Immunol. 69: 522-525 (2008).
Kanto T. Virus associated innate immunity in liver. Front. Biosci. 13: 6183-6192 (2008).
Kanto T, Hayashi N. Innate immunity in hepatitis C virus infection: interplay among dendritic cells, natural killer cells and natural killer T cells. Hepatol. Res. 37 Suppl. 3: S319-S326 (2007).
Kanwar JR, Kanwar RK. Gut health immunomodulatory and anti-inflammatory functions of gut enzyme digested high protein micro-nutrient dietary supplement - Enprocal. BMC Immunol. 10: 7 (2009). *
Kapessidou P, Poulin L, Dumoutier L, Goldman M, Renauld JC, Braun MY. Interleukin-22 deficiency accelerates the rejection of full major histocompatibility complex-disparate heart allografts. Transplant. Proc. 40: 1593-1597 (2008). *
Kapitany A, Tarr T, Gyetvai A, Szodoray P, Tumpek J, Poor G, Szegedi G, Sipka S, Kiss E. Human leukocyte antigen-DRB1 and -DQB1 genotyping in lupus patients with and without antiphospholipid syndrome. Ann. N. Y. Acad. Sci. 1173: 545-551 (2009). *
Kaplan MM, Bianchi DW. Primary biliary cirrhosis: for want of an X chromosome? Lancet 363: 505-506 (2004). *
Kappes DJ, He X, He X. Role of the transcription factor Th-POK in CD4:CD8 lineage commitment. Immunol. Rev. 209: 237-252 (2006).
Karabekian Z, Lytton SD, Silver PB, Sergeev YV, Schneck JP, Caspi RR. Antigen/MHC class II/Ig dimers for study of uveitogenic T cells: IRBP p161-180 presented by both IA and IE molecules. Invest. Ophthalmol. Vis. Sci. 46: 3769-3776 (2005). *
Karacki PS, Gao X, Thio CL, Thomas DL, Goedert JJ, Vlahov D, Kaslow RA, Strathdee S, Hilgartner MW, O'Brien SJ, Carrington M. MICA and recovery from hepatitis C virus and hepatitis B virus infections. Genes Immun. 5: 261-266 (2004). *
Karacsonyi C, Bedke T, Hinrichsen N, Schwinzer R, Lindner R. MHC II molecules and invariant chain reside in membranes distinct from conventional lipid rafts. J. Leukoc. Biol. 78: 1097-1105 (2005). *
Karadimitris A, Patterson S, Spanoudakis E. Natural killer T cells and haemopoiesis. Br. J. Haematol. 134: 263-272 (2006). *
Karason A, Gudjonsson JE, Jonsson HH, Hauksson VB, Runarsdottir EH, Stefansson K, Valdimarsson H, Gulcher JR. Genetics of psoriasis in Iceland: evidence for linkage of subphenotypes to distinct loci. J. Invest. Dermatol. 124: 1177-1185 (2005). *
Karlsen TH, Boberg KM, Olsson M, Sun JY, Senitzer D, Bergquist A, Schrumpf E, Thorsby E, Lie BA. Particular genetic variants of ligands for natural killer cell receptors may contribute to the HLA associated risk of primary sclerosing cholangitis. J. Hepatol. 46: 899-906 (2007). *
Karni A, Kohn Y, Safirman C, Abramsky O, Barcellos L, Oksenberg JR, Kahana E, Karussis D, Chapman J, Brautbar C. Evidence for the genetic role of human leukocyte antigens in low frequency DRB1*1501 multiple sclerosis patients in Israel. Mult. Scler. 5: 410-415 (1999). *
Karpenko O, Huang L, Dai Y. A probabilistic meta-predictor for the MHC class II binding peptides. Immunogenetics 60: 25-36 (2008). *
Kasai M, Tanida I, Ueno T, Kominami E, Seki S, Ikeda T, Mizuochi T. Autophagic compartments gain access to the MHC class II compartments in thymic epithelium. J. Immunol. 183: 7278-7285 (2009).
Kato M, Kinukawa T, Hattori R, Tsuji Y, Hirano A, Horie K, Tsuyuki M, Mizutani K. Does MICA influence acute rejection in kidney transplantation? Clin. Transpl. 2006: 389-393 (2006).
Kato Z, Stern JN, Nakamura HK, Kuwata K, Kondo N, Strominger JL. Positioning of autoimmune TCR-Ob.2F3 and TCR-Ob.3D1 on the MBP85-99/HLA-DR2 complex. Proc. Natl. Acad. Sci. U.S.A. 105: 15523-15528 (2008). *
Katsara M, Yuriev E, Ramsland PA, Deraos G, Tselios T, Matsoukas J, Apostolopoulos V. Mannosylation of mutated MBP(83-99) peptides diverts immune responses from Th1 to Th2. Mol. Immunol. 45: 3661-3670 (2008). *
Katsara M, Yuriev E, Ramsland PA, Tselios T, Deraos G, Lourbopoulos A, Grigoriadis N, Matsoukas J, Apostolopoulos V. Altered peptide ligands of myelin basic protein (MBP(87-89)) conjugated to reduced mannan modulate immune responses in mice. Immunology 128: 521-533 (2009). *
Katz G, Gazit R, Arnon TI, Gonen-Gross T, Tarcic G, Markel G, Gruda R, Achdout H, Drize O, Merims S, Mandelboim O. MHC class I-independent recognition of NK-activating receptor KIR2DS4. J. Immunol. 173: 1819-1825 (2004). *
Katz J, Zhang P, Martin M, Vogel SN, Michalek SM. Toll-like receptor 2 is required for inflammatory responses to Francisella tularensis LVS. Infect. Immun. 74: 2809-2816 (2006). *
Kaur G, Sarkar N, Bhatnagar S, Kumar S, Rapthap CC, Bhan MK, Mehra NK. Pediatric celiac disease in India is associated with multiple DR3-DQ2 haplotypes. Hum. Immunol. 63: 677-682 (2002).
Kaur M, Schmeier S, Macpherson CR, Hofmann O, Hide WA, Taylor S, Willcox N, Bajic VB. Prioritizing genes of potential relevance to diseases affected by sex hormones: an example of myasthenia gravis. BMC Genomics 9: 481 (2008). *
Kaushansky N, Eisenstein M, Oved JH, Ben-Nun A. Activation and control of pathogenic T cells in OSP/claudin-11-induced EAE in SJL/J mice are dominated by their focused recognition of a single epitopic residue (OSP58M). Int. Immunol. 20: 1439-1449 (2008).
Kaushansky N, Hemo R, Eisenstein M, Ben-Nun A. OSP/claudin-11-induced EAE in mice is mediated by pathogenic T cells primarily governed by OSP192Y residue of major encephalitogenic region OSP179-207. Eur. J. Immunol. 37: 2018-2031 (2007). *
Kavanagh B, Ko A, Venook A, Margolin K, Zeh H, Lotze M, Schillinger B, Liu W, Lu Y, Mitsky P, Schilling M, Bercovici N, Loudovaris M, Guillermo R, Lee SM, Bender J, Mills B, Fong L. Vaccination of metastatic colorectal cancer patients with matured dendritic cells loaded with multiple major histocompatibility complex class I peptides. J. Immunother. 30: 762-772 (2007).
Kawa S, Ota M, Yoshizawa K, Horiuchi A, Hamano H, Ochi Y, Nakayama K, Tokutake Y, Katsuyama Y, Saito S, Hasebe O, Kiyosawa K. HLA DRB10405-DQB10401 haplotype is associated with autoimmune pancreatitis in the Japanese population. Gastroenterology 122: 1264-1269 (2002). *
Kawabata Y, Ikegami H, Kawaguchi Y, Fujisawa T, Hotta M, Ueda H, Shintani M, Nojima K, Ono M, Nishino M, Taniguchi H, Noso S, Yamada K, Babaya N, Ogihara T. Age-related association of MHC class I chain-related gene A (MICA) with type 1 (insulin-dependent) diabetes mellitus. Hum. Immunol. 61: 624-629 (2000).
Kawada M, Igarashi H, Takeda A, Tsukamoto T, Yamamoto H, Dohki S, Takiguchi M, Matano T. Involvement of multiple epitope-specific cytotoxic T-lymphocyte responses in vaccine-based control of simian immunodeficiency virus replication in rhesus macaques. J. Virol. 80: 1949-1958 (2006). *
Kawahara M, York IA, Hearn A, Farfan D, Rock KL. Analysis of the role of tripeptidyl peptidase II in MHC class I antigen presentation in vivo. J. Immunol. 183: 6069-6077 (2009).
Kawahara Y, Mizuno M, Yoshino T, Yokota K, Oguma K, Okada H, Fujiki S, Shiratori Y. HLA-DQA1*0103-DQB1*0601 haplotype and Helicobacter pylori-positive gastric mucosa-associated lymphoid tissue lymphoma. Clin. Gastroenterol. Hepatol. 3: 865-868 (2005).
Kawahito Y, Cannon GW, Gulko PS, Remmers EF, Longman RE, Reese VR, Wang J, Griffiths MM, Wilder RL. Localization of quantitative trait loci regulating adjuvant-induced arthritis in rats: evidence for genetic factors common to multiple autoimmune diseases. J. Immunol. 161: 4411-4419 (1998). *
Kawamura K, Kadowaki N, Suzuki R, Udagawa S, Kasaoka S, Utoguchi N, Kitawaki T, Sugimoto N, Okada N, Maruyama K, Uchiyama T. Dendritic cells that endocytosed antigen-containing IgG-liposomes elicit effective antitumor immunity. J. Immunother. 29: 165-174 (2006).
Kawamura K, McLaughlin KA, Weissert R, Forsthuber TG. Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. J. Immunol. 181: 3202-3211 (2008). *
Kawanishi H, Mirabella S. Regulation of mucosal IgA production in vitro by autoreactive immunoregulatory T cells from murine Peyer's patches. Cell. Immunol. 114: 324-335 (1988). *
Kawano H, Abe M, Zhang D, Saikawa T, Fujimori M, Hirose S, Shirai T. Heterozygosity of the major histocompatibility complex controls the autoimmune disease in (NZW x BXSB) F1 mice. Clin. Immunol. Immunopathol. 65: 308-314 (1992).
Kawanokuchi J, Mizuno T, Takeuchi H, Kato H, Wang J, Mitsuma N, Suzumura A. Production of interferon-gamma by microglia. Mult. Scler. 12: 558-564 (2006). *
Kawaoka T, Oka M, Takashima M, Ueno T, Yamamoto K, Yahara N, Yoshino S, Hazama S. Adoptive immunotherapy for pancreatic cancer: cytotoxic T lymphocytes stimulated by the MUC1-expressing human pancreatic cancer cell line YPK-1. Oncol. Rep. 20: 155-163 (2008). *
Kawasaki E, Matsuura N, Eguchi K. Type 1 diabetes in Japan. Diabetologia 49: 828-836 (2006). *
Kawasaki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH. Effect of interleukin-15 on depressed splenic dendritic cell functions following trauma-hemorrhage. Am. J. Physiol. Cell Physiol. 296: C124-C130 (2009). *
Kay TW, Dudek NL, Graham K, Estella E, Angstetra E, McKenzie MD, Allison J, Thomas HE. Cytotoxic T cell mechanisms of beta cell destruction in non-obese diabetic mice. Novartis Found. Symp. 292: 68-78 (2008).
Keane OM, Dodds KG, Crawford AM, McEwan JC. Transcriptional profiling of Ovis aries identifies Ovar-DQA1 allele frequency differences between nematode resistant and susceptible selection lines. Physiol. Genomics 30: 253-261 (2007). *
Kearney M, Maldarelli F, Shao W, Margolick JB, Daar ES, Mellors JW, Rao V, Coffin JM, Palmer S. Human immunodeficiency virus type 1 population genetics and adaptation in newly infected individuals. J. Virol. 83: 2715-2727 (2009). *
Kedzierska A, Turowski G. Histocompatibility HLA system of man. Consideration in the light of current concepts. I. Organization and polymorphism. Przegl. Lek. 58: 459-462 (2001).
Kedzierska A, Turowski G. Histocompatibility HLA system in man. Considerations in the light of current concept. Part III. The relationship between HLA antigens and disease susceptibility. Przegl. Lek. 58: 814-817 (2001).
Keech CL, Pang KC, McCluskey J, Chen W. Direct antigen presentation by dendritic cells shapes the functional CD8+T cell repertoire against the nuclear self-antigen La-SSB. Eur. J. Immunol. Nov 30 [Epub ahead of print] (2009). *
Keicho N, Ohashi J, Tamiya G, Nakata K, Taguchi Y, Azuma A, Ohishi N, Emi M, Park MH, Inoko H, Tokunaga K, Kudoh S. Fine localization of a major disease-susceptibility locus for diffuse panbronchiolitis. Am. J. Hum. Genet. 66: 501-507 (2000). *
Kel J, Oldenampsen J, Luca M, Drijfhout JW, Koning F, Nagelkerken L. Soluble mannosylated myelin peptide inhibits the encephalitogenicity of autoreactive T cells during experimental autoimmune encephalomyelitis. Am. J. Pathol. 170: 272-280 (2007). *
Kelemen K, Gottlieb PA, Putnam AL, Davidson HW, Wegmann DR, Hutton JC. HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes. J. Immunol. 172: 3955-3962 (2004). *
Keler T, Ramakrishna V, Fanger MW. Mannose receptor-targeted vaccines. Expert Opin. Biol. Ther. 4: 1953-1962 (2004).
Keller SA, Bauer M, Manolova V, Muntwiler S, Saudan P, Bachmann MF. Cutting edge: limited specialization of dendritic cell subsets for MHC class II-associated presentation of viral particles. J. Immunol. 184: 26-29 (2010).
Kelley J, de Bono B, Trowsdale J. IRIS: a database surveying known human immune system genes. Genomics 85: 503-511 (2005). *
Kelley J, Trowsdale J. Features of MHC and NK gene clusters. Transpl. Immunol. 14: 129-134 (2005).
Kelley J, Walter L, Trowsdale J. Comparative genomics of natural killer cell receptor gene clusters. PLoS Genet. 1: 129-139 (2005). *
Kelley JM, Hughes LB, Feng R, Liu N, Padilla MA, Vaughan LK, Bridges SL Jr. Evaluating linkage disequilibrium and recombination provides a haplotype-tagging SNP panel of the major histocompatibility complex in African Americans. Genes Immun. 9: 271-273 (2008). *
Kellner H, Yu D. The pathogenesis of HLA-B27 associated arthritis: lessons from the B27 crystal. Clin. Investig. 72: 321-328 (1994).
Kelly-Rogers J, Madrigal-Estebas L, O'Connor T, Doherty DG. Activation-induced expression of CD56 by T cells is associated with a reprogramming of cytolytic activity and cytokine secretion profile in vitro. Hum. Immunol. 67: 863-873 (2006).
Kenealy SJ, Babron MC, Bradford Y, Schnetz-Boutaud N, Haines JL, Rimmler JB, Schmidt S, Pericak-Vance MA, Barcellos LF, Lincoln RR, Oksenberg JR, Hauser SL, Clanet M, Brassat D, Edan G, Yaouanq J, Semana G, Cournu-Rebeix I, Lyon-Caen O, Fontaine B. A second-generation genomic screen for multiple sclerosis. Am. J. Hum. Genet. 75: 1070-1078 (2004). *
Kenna TJ, Waldie T, McNally A, Thomson M, Yagita H, Thomas R, Steptoe RJ. Targeting antigen to diverse APCs inactivates memory CD8+ T cells without eliciting tissue-destructive effector function. J. Immunol. 184: 598-606 (2010).
Kennedy LJ, Barnes A, Ollier WE, Day MJ. Association of a common dog leucocyte antigen class II haplotype with canine primary immune-mediated haemolytic anaemia. Tissue Antigens 68: 502-508 (2006). *
Kennedy LJ, Barnes A, Short A, Brown JJ, Lester S, Seddon J, Happ GM, Ollier WE. Canine DLA diversity: 2. Family studies. Tissue Antigens 69 Suppl. 1: 289-291 (2007). *
Kennedy LJ, Davison LJ, Barnes A, Short AD, Fretwell N, Jones CA, Lee AC, Ollier WE, Catchpole B. Identification of susceptibility and protective major histocompatibility complex haplotypes in canine diabetes mellitus. Tissue Antigens 68: 467-476 (2006). *
Kennedy LJ, Huson HJ, Leonard J, Angles JM, Fox LE, Wojciechowski JW, Yuncker C, Happ GM. Association of hypothyroid disease in Doberman Pinscher dogs with a rare major histocompatibility complex DLA class II haplotype. Tissue Antigens 67: 53-56 (2006).
Kennedy LJ, O'Neill T, House A, Barnes A, Kyostila K, Innes J, Fretwell N, Day MJ, Catchpole B, Lohi H, Ollier WE. Risk of anal furunculosis in German Shepherd dogs is associated with the major histocompatibility complex. Tissue Antigens 71: 51-56 (2008). *
Kerkvliet NI, Shepherd DM, Baecher-Steppan L. T lymphocytes are direct, aryl hydrocarbon receptor (AhR)-dependent targets of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD): AhR expression in both CD4+ and CD8+ T cells is necessary for full suppression of a cytotoxic T lymphocyte response by TCDD. Toxicol. Appl. Pharmacol. 185: 146-152 (2002). *
Kern F, LiPira G, Gratama JW, Manca F, Roederer M. Measuring Ag-specific immune responses: understanding immunopathogenesis and improving diagnostics in infectious disease, autoimmunity and cancer. Trends Immunol. 26: 477-484 (2005). *
Kettaneh A, Seng L, Tiev KP, Toledano C, Fabre B, Cabane J. Human leukocyte antigens and susceptibility to tuberculosis: a meta-analysis of case-control studies. Int. J. Tuberc. Lung Dis. 10: 717-725 (2006).
Keusekotten K, Leonhardt RM, Ehses S, Knittler MR. Biogenesis of functional antigenic peptide-transporter TAP requires assembly of pre-existing TAP1 with newly synthesized TAP2. J. Biol. Chem. 281: 17545-17551 (2006). *
Keyeux G, Lefranc MP, Chevailler A, Lefranc G. Molecular analysis of the IGHA and MHC class III region genes in one family with IgA and C4 deficiencies. Exp. Clin. Immunogenet. 7: 170-180 (1990).
Khadra A, Santamaria P, Edelstein-Keshet L. The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation. J. Theor. Biol. 256: 126-141 (2009). *
Khakoo SI, Brooks CR. MHC class I receptors on natural killer cells: on with the old and in with the new. Clin. Sci. (Lond.) 105: 127-140 (2003). *
Khakoo SI, Thio CL, Martin MP, Brooks CR, Gao X, Astemborski J, Cheng J, Goedert JJ, Vlahov D, Hilgartner M, Cox S, Little AM, Alexander GJ, Cramp ME, O'Brien SJ, Rosenberg WM, Thomas DL, Carrington M. HLA and NK cell inhibitory receptor genes in resolving hepatitis C virus infection. Science 305: 872-874 (2004). *
Khalil H, Brunet A, Thibodeau J. A three-amino-acid-long HLA-DRbeta cytoplasmic tail is sufficient to overcome ER retention of invariant-chain p35. J. Cell. Sci. 118: 4679-4687 (2005). *
Khan MA, Gallo RM, Renukaradhya GJ, Du W, Gervay-Hague J, Brutkiewicz RR. Statins impair CD1d-mediated antigen presentation through the inhibition of prenylation. J. Immunol. 182: 4744-4750 (2009).
Khan MA, Kellner H. Immunogenetics of spondyloarthropathies. Rheum. Dis. Clin. North Am. 18: 837-864 (1992).
Khan MA, Kushner I, Braun WE. Association of HLA-A2 with uveitis in HLA-B27 positive patients with ankylosing spondylitis. J. Rheumatol. 8: 295-298 (1981).
Khandoga A, Hanschen M, Kessler JS, Krombach F. CD4(+) T cells contribute to postischemic liver injury in mice by interacting with sinusoidal endothelium and platelets. Hepatology 43: 306-315 (2006). *
Khani-Hanjani A, Lacaille D, Hoar D, Chalmers A, Horsman D, Anderson M, Balshaw R, Keown PA. Association between dinucleotide repeat in non-coding region of interferon-gamma gene and susceptibility to, and severity of, rheumatoid arthritis. Lancet 356: 820-825 (2000). *
Khani-Hanjani A, Lacaille D, Horne C, Chalmers A, Hoar DI, Balshaw R, Keown PA. Expression of QK/QR/RRRAA or DERAA motifs at the third hypervariable region of HLA-DRB1 and disease severity in rheumatoid arthritis. J. Rheumatol. 29: 1358-1365 (2002).
Khayrullina T, Yen JH, Jing H, Ganea D. In vitro differentiation of dendritic cells in the presence of prostaglandin E2 alters the IL-12/IL-23 balance and promotes differentiation of Th17 cells. J. Immunol. 181: 721-735 (2008). *
Khurana A, Kronenberg M. A method for production of recombinant mCD1d protein in insect cells. J. Vis. Exp. 10: 556 (2007). *
Kielmanowicz MG, Laham N, Coligan JE, Lemonnier F, Ehrlich R. Mouse HFE inhibits Tf-uptake and iron accumulation but induces non-transferrin bound iron (NTBI)-uptake in transformed mouse fibroblasts. J. Cell. Physiol. 202: 105-114 (2004). *
Kienast A, Preuss M, Winkler M, Dick TP. Redox regulation of peptide receptivity of major histocompatibility complex class I molecules by ERp57 and tapasin. Nat. Immunol. 8: 864-872 (2007). *
Kiesel JR, Buchwald ZS, Aurora R. Cross-presentation by osteoclasts induces FoxP3 in CD8+ T cells. J. Immunol. 182: 5477-5487 (2009).
Kilding R, Akil M, Till S, Amos R, Winfield J, Iles MM, Wilson AG. A biologically important single nucleotide polymorphism within the Toll-like receptor-4 gene is not associated with rheumatoid arthritis. Clin. Exp. Rheumatol. 21: 340-342 (2003).
Kilding R, Wilson AG. Mapping of a novel susceptibility gene for rheumatoid arthritis in the telomeric MHC region. Cytokine 32: 71-75 (2005).
Kim CY, Quarsten H, Bergseng E, Khosla C, Sollid LM. Structural basis for HLA-DQ2-mediated presentation of gluten epitopes in celiac disease. Proc. Natl. Acad. Sci. U.S.A. 101: 4175-4179 (2004). *
Kim DH, Jung HD, Kwack DH, Lee NY, Sohn SK, Baek JH, Kim JG, Suh JS, Lee KB, Shin IH. Predicting outcomes of HLA-identical allogeneic stem cell transplants from variable number of tandem repeat disparity between donors and recipients. Haematologica 91: 71-77 (2006). *
Kim E, Kwak H, Ahn K. Cytosolic aminopeptidases influence MHC class I-mediated antigen presentation in an allele-dependent manner. J. Immunol. 183: 7379-7387 (2009).
Kim GY, Kim JH, Ahn SC, Lee HJ, Moon DO, Lee CM, Park YM. Lycopene suppresses the lipopolysaccharide-induced phenotypic and functional maturation of murine dendritic cells through inhibition of mitogen-activated protein kinases and nuclear factor-kB. Immunology 113: 203-211 (2004). *
Kim HJ, Guo D, Sant'Angelo DB. Coevolution of TCR-MHC interactions: conserved MHC tertiary structure is not sufficient for interactions with the TCR. Proc. Natl. Acad. Sci. U.S.A. 102: 7263-7267 (2005). *
Kim HJ, Hwang SJ, Kim BK, Jung KC, Chung DH. NKT cells play critical roles in the induction of oral tolerance by inducing regulatory T cells producing IL-10 and transforming growth factor beta, and by clonally deleting antigen-specific T cells. Immunology 118: 101-111 (2006). *
Kim JI, Sonawane SB, Lee MK, Lee SH, Duff PE, Moore DJ, O'Connor MR, Lian MM, Deng S, Choi Y, Yeh H, Caton AJ, Markmann JF. Blockade of GITR-GITRL interaction maintains regulatory T cell function to prolong allograft survival. Eur. J. Immunol. Feb 10 [Epub ahead of print] (2010). *
Kim JJ, Hong SJ, Hong YM, Kim S, Kang MJ, Kim KJ, Seo EJ, Yoo HW, Cheong HS, Shin HD, Park IS, Lee JK. Genetic variants in the HLA-G region are associated with Kawasaki disease. Hum. Immunol. 69: 867-871 (2008).
Kim K, Lerou P, Yabuuchi A, Lengerke C, Ng K, West J, Kirby A, Daly MJ, Daley GQ. Histocompatible embryonic stem cells by parthenogenesis. Science 315: 482-486 (2007). *
Kim K, Wang L, Hwang I. A novel flow cytometric high throughput assay for a systematic study on molecular mechanisms underlying T cell receptor-mediated integrin activation. PLoS One 4: e6044 (2009). *
Kim R, Emi M, Tanabe K. Cancer immunoediting from immune surveillance to immune escape. Immunology 121: 1-14 (2007). *
Kim S, Poursine-Laurent J, Truscott SM, Lybarger L, Song YJ, Yang L, French AR, Sunwoo JB, Lemieux S, Hansen TH, Yokoyama WM. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436: 709-713 (2005). *
Kim S, Sunwoo JB, Yang L, Choi T, Song YJ, French AR, Vlahiotis A, Piccirillo JF, Cella M, Colonna M, Mohanakumar T, Hsu KC, Dupont B, Yokoyama WM. HLA alleles determine differences in human natural killer cell responsiveness and potency. Proc. Natl. Acad. Sci. U.S.A. 105: 3053-3058 (2008). *
Kim SH, Bianco NR, Shufesky WJ, Morelli AE, Robbins PD. Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4. J. Immunol. 179: 2242-2249 (2007). *
Kim SK, Im J, Yun CH, Son JY, Son CG, Park DK, Han SH. Armillariella mellea induces maturation of human dendritic cells without induction of cytokine expression. J. Ethnopharmacol. 119: 153-159 (2008).
Kim SK, Son CG, Yun CH, Han SH. Hericium erinaceum induces maturation of dendritic cells derived from human peripheral blood monocytes. Phytother. Res. 24: 14-19 (2009).
Kim TW, Choi YM, Seo JN, Kim JH, Suh YH, Chung DH, Jung KC, Oh KI. Delayed allograft rejection by the suppression of class II transactivator. Exp. Mol. Med. 38: 210-216 (2006). *
Kimura T, Suzuki K, Inada S, Hayashi A, Isobe M, Matsuzaki Y, Tanaka N, Osuga T, Fujiwara M. Monoclonal antibody against lymphocyte function-associated antigen 1 inhibits the formation of primary biliary cirrhosis-like lesions induced by murine graft-versus-host reaction. Hepatology 24: 888-894 (1996). *
Kimura T, Suzuki K, Inada S, Hayashi A, Saito H, Miyai T, Ohsugi Y, Matsuzaki Y, Tanaka N, Osuga T, et al. Induction of autoimmune disease by graft-versus-host reaction across MHC class II difference: modification of the lesions in IL-6 transgenic mice. Clin. Exp. Immunol. 95: 525-529 (1994). *
Kindmark A, Jawaid A, Harbron CG, Barratt BJ, Bengtsson OF, Andersson TB, Carlsson S, Cederbrant KE, Gibson NJ, Armstrong M, Lagerstrom-Fermer ME, Dellsen A, Brown EM, Thornton M, Dukes C, Jenkins SC, Firth MA, Harrod GO, Pinel TH, et al. Genome-wide pharmacogenetic investigation of a hepatic adverse event without clinical signs of immunopathology suggests an underlying immune pathogenesis. Pharmacogenomics J. 8: 186-195 (2008). *
King AL, Ciclitira PJ. Celiac disease: strongly heritable, oligogenic, but genetically complex. Mol. Genet. Metab. 71: 70-75 (2000). *
King AL, Yiannakou JY, Brett PM, Curtis D, Morris MA, Dearlove AM, Rhodes M, Rosen-Bronson S, Mathew C, Ellis HJ, Ciclitira PJ. A genome-wide family-based linkage study of coeliac disease. Ann. Hum. Genet. 64: 479-490 (2000). *
Kirschner DE, Chang ST, Riggs TW, Perry N, Linderman JJ. Toward a multiscale model of antigen presentation in immunity. Immunol. Rev. 216: 93-118 (2007). *
Kirsten H, Petit-Teixeira E, Scholz M, Hasenclever D, Hantmann H, Heider D, Wagner U, Sack U, Teixeira VH, Prum B, Burkhardt J, Pierlot C, Emmrich F, Cornelis F, Ahnert P. Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study. Arthritis Res. Ther. 11: R60 (2009). *
Kish DD, Gorbachev AV, Fairchild RL. Regulatory function of CD4+CD25+ T cells from class II MHC-deficient mice in contact hypersensitivity responses. J. Leukoc. Biol. 82: 85-92 (2007). *
Kiszel P, Kovacs M, Szalai C, Yang Y, Pozsonyi E, Blasko B, Laki J, Prohaszka Z, Fazakas A, Panczel P, Hosszufalusi N, Rajczy K, Wu YL, Chung EK, Zhou B, Blanchong CA, Vatay A, Yu CY, Fust G. Frequency of carriers of 8.1 ancestral haplotype and its fragments in two Caucasian populations. Immunol. Invest. 36: 307-319 (2007). *
Kita H. Autoreactive CD8-specific T-cell response in primary biliary cirrhosis. Hepatol. Res. 37 Suppl. 3: S402-S405 (2007). *
Kita H, Ansari AA, He XS, Lian ZX, Van de Water J, Coppel RL, Luketic V, Kaplan M, Inamori H, Isoda N, Sugano K, Imawari M, Gershwin ME. Proteasome is required for class I-restricted presentation by Fcgamma receptor-mediated endocytosis in primary biliary cirrhosis. J. Autoimmun. 21: 175-182 (2003). *
Kita H, He XS, Gershwin ME. Application of tetramer technology in studies on autoimmune diseases. Autoimmun. Rev. 2: 43-49 (2003).
Kita H, Lian ZX, Van de Water J, He XS, Matsumura S, Kaplan M, Luketic V, Coppel RL, Ansari AA, Gershwin ME. Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells. J. Exp. Med. 195: 113-123 (2002). *
Kita H, Matsumura S, He XS, Ansari AA, Lian ZX, Van de Water J, Coppel RL, Kaplan MM, Gershwin ME. Quantitative and functional analysis of PDC-E2-specific autoreactive cytotoxic T lymphocytes in primary biliary cirrhosis. J. Clin. Invest. 109: 1231-1240 (2002). *
Kitamura H, Kamon H, Sawa S, Park SJ, Katunuma N, Ishihara K, Murakami M, Hirano T. IL-6-STAT3 controls intracellular MHC class II alphabeta dimer level through cathepsin S activity in dendritic cells. Immunity 23: 491-502 (2005). *
Kitamura H, Morikawa H, Kamon H, Iguchi M, Hojyo S, Fukada T, Yamashita S, Kaisho T, Akira S, Murakami M, Hirano T. Toll-like receptor-mediated regulation of zinc homeostasis influences dendritic cell function. Nat. Immunol. 7: 971-977 (2006). *
Kitchens WH, Uehara S, Chase CM, Colvin RB, Russell PS, Madsen JC. The changing role of natural killer cells in solid organ rejection and tolerance. Transplantation 81: 811-817 (2006).
Kittur D, Shimizu Y, DeMars R, Edidin M. Insulin binding to human B lymphoblasts is a function of HLA haplotype. Proc. Natl. Acad. Sci. U.S.A. 84: 1351-1355 (1987). *
Kiura K, Kataoka H, Nakata T, Into T, Yasuda M, Akira S, Inoue N, Shibata K. The synthetic analogue of mycoplasmal lipoprotein FSL-1 induces dendritic cell maturation through Toll-like receptor 2. FEMS Immunol. Med. Microbiol. 46: 78-84 (2006). *
Klareskog L, Padyukov L, Ronnelid J, Alfredsson L. Genes, environment and immunity in the development of rheumatoid arthritis. Curr. Opin. Immunol. 18: 650-655 (2006).
Klareskog L, Ronnelid J, Lundberg K, Padyukov L, Alfredsson L. Immunity to citrullinated proteins in rheumatoid arthritis. Annu. Rev. Immunol. 26: 651-675 (2008). *
Klein I, Gassel HJ, Crispe IN. Cytotoxic T-cell response following mouse liver transplantation is independent of the initial site of T-cell priming. Transplant. Proc. 38: 3241-3243 (2006). *
Klein J, Sato A, Nikolaidis N. MHC, TSP, and the origin of species: from immunogenetics to evolutionary genetics. Annu. Rev. Genet. 41: 281-304 (2007). *
Klein L, Hinterberger M, Wirnsberger G, Kyewski B. Antigen presentation in the thymus for positive selection and central tolerance induction. Nat. Rev. Immunol. 9: 833-844 (2009). *
Kline J, Subbiah S, Lazarus HM, van Besien K. Autologous graft-versus-host disease: harnessing anti-tumor immunity through impaired self-tolerance. Bone Marrow Transplant. 41: 505-513 (2008). *
Kloetzel PM. The proteasome and MHC class I antigen processing. Biochim. Biophys. Acta 1695: 225-233 (2004). *
Kloetzel PM. Generation of major histocompatibility complex class I antigens: functional interplay between proteasomes and TPPII. Nat. Immunol. 5: 661-669 (2004). *
Kloetzel PM, Ossendorp F. Proteasome and peptidase function in MHC-class-I-mediated antigen presentation. Curr. Opin. Immunol. 16: 76-81 (2004).
Kloss M, Decker P, Baltz KM, Baessler T, Jung G, Rammensee HG, Steinle A, Krusch M, Salih HR. Interaction of monocytes with NK cells upon Toll-like receptor-induced expression of the NKG2D ligand MICA. J. Immunol. 181: 6711-6719 (2008). *
Klotz L, Hucke S, Thimm D, Classen S, Gaarz A, Schultze J, Edenhofer F, Kurts C, Klockgether T, Limmer A, Knolle P, Burgdorf S. Increased antigen cross-presentation but impaired cross-priming after activation of peroxisome proliferator-activated receptor gamma is mediated by up-regulation of B7H1. J. Immunol. 183: 129-136 (2009).
Klug F, Miller M, Schmidt HH, Stevanovic S. Characterization of MHC ligands for peptide based tumor vaccination. Curr. Pharm. Des. 15: 3221-3236 (2009).
Klyushnenkova EN, Kouiavskaia DV, Berard CA, Alexander RB. Cutting edge: permissive MHC class II allele changes the pattern of antitumor immune response resulting in failure of tumor rejection. J. Immunol. 182: 1242-1246 (2009).
Kmiec Z. Cooperation of liver cells in health and disease. Adv. Anat. Embryol. Cell. Biol. 161: III-XIII, 1-151 (2001).
Knapp B, Omasits U, Bohle B, Maillere B, Ebner C, Schreiner W, Jahn-Schmid B. 3-Layer-based analysis of peptide-MHC interaction: in silico prediction, peptide binding affinity and T cell activation in a relevant allergen-specific model. Mol. Immunol. 46: 1839-1844 (2009). *
Knapp LA. Single nucleotide polymorphism screening with denaturing gradient gel electrophoresis. Methods Mol. Biol. 578: 137-151 (2009). *
Knapp LA, Robson J, Waterhouse JS. Olfactory signals and the MHC: a review and a case study in Lemur catta. Am. J. Primatol. 68: 568-584 (2006). *
Knapp S, Warshow U, Hegazy D, Brackenbury L, Guha IN, Fowell A, Little AM, Alexander GJ, Rosenberg WM, Cramp ME, Khakoo SI. Consistent beneficial effects of killer cell immunoglobulin-like receptor 2DL3 and group 1 human leukocyte antigen-C following exposure to hepatitis C virus. Hepatology Nov 30 [Epub ahead of print] (2009). *
Knechtle SJ, Kwun J. Unique aspects of rejection and tolerance in liver transplantation. Semin. Liver Dis. 29: 91-101 (2009).
Knoerzer DB, Karr RW, Schwartz BD, Mengle-Gaw LJ. Collagen-induced arthritis in the BB rat. Prevention of disease by treatment with CTLA-4-Ig. J. Clin. Invest. 96: 987-993 (1995). *
Knolle P. Immunological functions. Falk Symposium 138. XII FALK LIVER WEEK 2003 (Part III) In Honour of Hans Popper�s 100th Birthday. State-of-the-art of hepatology: Molecular and Cell Biology. Freiburg (Germany). p. 23. October 20 - 21 (2003). *
Knolle PA. Chapter 2. Role and function of liver sinusoidal endothelial cells. In "Liver Immunology: Principles and Practice" (eds. Gershwin ME, Vierling JM, Manns MP), Humana Press Inc., Totowa, NJ, p. 25-39 (2007). *
Knolle PA. The liver and its contribution to induction of oral tolerance. Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, p. 53 (2005). *
Knutson KL, Disis ML. Tumor antigen-specific T helper cells in cancer immunity and immunotherapy. Cancer Immunol. Immunother. 54: 721-728 (2005). *
Kobashi H, Yamamoto K, Yoshioka T, Tomita M, Tsuji T. Nonsuppurative cholangitis is induced in neonatally thymectomized mice: a possible animal model for primary biliary cirrhosis. Hepatology 19: 1424-1430 (1994).
Kobayashi A, Kasano M, Maeda T, Hori S, Motojima K, Suzuki M, Fujiwara T, Takahashi E, Yabe T, Tanaka K, Kasahara M, Yamaguchi Y, Maeda M. A half-type ABC transporter TAPL is highly conserved between rodent and man, and the human gene is not responsive to interferon-gamma in contrast to TAP1 and TAP2. J. Biochem. 128: 711-718 (2000).
Kobayashi H, Kimura S, Aoki N, Sato K, Celis E, Katagiri M. Existence of MHC class I-restricted alloreactive CD4+ T cells reacting with peptide transporter-deficient cells. Immunogenetics 53: 626-633 (2001).
Kobayashi KS, Flavell RA. Shielding the double-edged sword: negative regulation of the innate immune system. J. Leukoc. Biol. 75: 428-433 (2004). *
Koch J, Guntrum R, Tampe R. Exploring the minimal functional unit of the transporter associated with antigen processing. FEBS Lett. 579: 4413-4416 (2005). *
Koch J, Tampe R. The macromolecular peptide-loading complex in MHC class I-dependent antigen presentation. Cell. Mol. Life Sci. 63: 653-662 (2006). *
Koch N, McLellan AD, Neumann J. A revised model for invariant chain-mediated assembly of MHC class II peptide receptors. Trends Biochem. Sci. 32: 532-537 (2007). *
Koehn J, Huesken D, Jaritz M, Rot A, Zurini M, Dwertmann A, Beutler B, Korthauer U. Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response. Hum. Immunol. 68: 871-878 (2007).
Koeleman BP, Herr MH, Zavattari P, Dudbridge F, March R, Campbell D, Barnett AH, Bain SC, Mulargia AP, Loddo M, Amos W, Cucca F, Todd JA. Conditional ETDT analysis of the human leukocyte antigen region in type 1 diabetes. Ann. Hum. Genet. 64: 215-221 (2000).
Koeleman BP, Lie BA, Undlien DE, Dudbridge F, Thorsby E, de Vries RR, Cucca F, Roep BO, Giphart MJ, Todd JA. Genotype effects and epistasis in type 1 diabetes and HLA-DQ trans dimer associations with disease. Genes Immun. 5: 381-388 (2004). *
Kohga K, Takehara T, Tatsumi T, Ishida H, Miyagi T, Hosui A, Hayashi N. Sorafenib inhibits the shedding of major histocompatibility complex class I-related chain A on hepatocellular carcinoma cells by down-regulating a disintegrin and metalloproteinase 9. Hepatology Nov 30 [Epub ahead of print] (2009). *
Kohn LD, Napolitano G, Singer DS, Molteni M, Scorza R, Shimojo N, Kohno Y, Mozes E, Nakazato M, Ulianich L, Chung HK, Matoba H, Saunier B, Suzuki K, Schuppert F, Saji M. Graves' disease: a host defense mechanism gone awry. Int. Rev. Immunol. 19: 633-664 (2000).
Kohoutek J, Blazek D, Peterlin BM. Hexim1 sequesters positive transcription elongation factor b from the class II transactivator on MHC class II promoters. Proc. Natl. Acad. Sci. U.S.A. 103: 17349-17354 (2006). *
Kohyama M, Hachimura S, Nanno M, Ishikawa H, Kaminogawa S. Analysis of cytokine producing activity of intestinal intraepithelial T cells from TCR beta-chain and delta-chain mutant mice. Microbiol. Immunol. 41: 353-359 (1997).
Koizumi K, Okamoto H, Iikuni N, Nakamura T, Kawamoto M, Momohara S, Ichikawa N, Furuya T, Kotake S, Taniguchi A, Yamanaka H, Kamatani N. Single nucleotide polymorphisms in the gene encoding the major histocompatibility complex class II transactivator (CIITA) in systemic lupus erythematosus. Ann. Rheum. Dis. 64: 947-950 (2005). *
Kokaraki G, Daniilidis M, Yiangou M, Arsenakis M, Karyotis N, Tsilipakou M, Fleva A, Gerofotis A, Karadani N, Yovos JG. Major histocompatibility complex class II (DRB1*, DQA1*, and DQB1*) and DRB1*04 subtypes' associations of Hashimoto's thyroiditis in a Greek population. Tissue Antigens 73: 199-205 (2009). *
Kokhaei P, Palma M, Hansson L, Osterborg A, Mellstedt H, Choudhury A. Telomerase (hTERT 611-626) serves as a tumor antigen in B-cell chronic lymphocytic leukemia and generates spontaneously antileukemic, cytotoxic T cells. Exp. Hematol. 35: 297-304 (2007). *
Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA, Harris HE. RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages. Scand. J. Immunol. 61: 1-9 (2005). *
Koller M, Zwolfer B, Steiner G, Smolen JS, Scheinecker C. Phenotypic and functional deficiencies of monocyte-derived dendritic cells in systemic lupus erythematosus (SLE) patients. Int. Immunol. 16: 1595-1604 (2004). *
Kolly R, Thiel MA, Herrmann T, Pluckthun A. Monovalent antibody scFv fragments selected to modulate T-cell activation by inhibition of CD86-CD28 interaction. Protein Eng. Des. Sel. 20: 91-98 (2007). *
Komatsu-Wakui M, Tokunaga K, Ishikawa Y, Leelayuwat C, Kashiwase K, Tanaka H, Moriyama S, Nakajima F, Park MH, Jia GJ, Chimge NO, Sideltseva EW, Juji T. Wide distribution of the MICA-MICB null haplotype in East Asians. Tissue Antigens 57: 1-8 (2001). *
Kong W, Yen JH, Vassiliou E, Adhikary S, Toscano MG, Ganea D. Docosahexaenoic acid prevents dendritic cell maturation and in vitro and in vivo expression of the IL-12 cytokine family. Lipids Health Dis. 9: 12 (2010). *
Kong YC, Flynn JC, Banga JP, David CS. Application of HLA class II transgenic mice to study autoimmune regulation. Thyroid 17: 995-1003 (2007).
Kong YC, Jacob JB, Flynn JC, Elliott BE, Wei WZ. Autoimmune thyroiditis as an indicator of autoimmune sequelae during cancer immunotherapy. Autoimmun. Rev. 9: 28-33 (2009).
Kong YC, Lomo LC, Motte RW, Giraldo AA, Baisch J, Strauss G, Hammerling GJ, David CS. HLA-DRB1 polymorphism determines susceptibility to autoimmune thyroiditis in transgenic mice: definitive association with HLA-DRB1*0301 (DR3) gene. J. Exp. Med. 184: 1167-1172 (1996). *
Kong YC, Morris GP, Brown NK, Yan Y, Flynn JC, David CS. Autoimmune thyroiditis: a model uniquely suited to probe regulatory T cell function. J. Autoimmun. 33: 239-246 (2009).
Kong YC, Wei WZ, Tomer Y. Opportunistic autoimmune disorders. Ann. N. Y. Acad. Sci. 1183: 222-236 (2010). *
Konkel JE, Frommer F, Leech MD, Yagita H, Waisman A, Anderton SM. PD-1 signalling in CD4(+) T cells restrains their clonal expansion to an immunogenic stimulus, but is not critically required for peptide-induced tolerance. Immunology Jan 27 [Epub ahead of print] (2010). *
Kopp T, Lenz P, Bello-Fernandez C, Kastelein RA, Kupper TS, Stingl G. IL-23 production by cosecretion of endogenous p19 and transgenic p40 in keratin 14/p40 transgenic mice: evidence for enhanced cutaneous immunity. J. Immunol. 170: 5438-5444 (2003). *
Kordi Tamandani DM, Sobti RC, Shekari M, Husseini SA, Suri V. No association of TAP1 and TAP2 genes polymorphism with risk of cervical cancer in north Indian population. J. Assist. Reprod. Genet. 26: 173-178 (2009).
Korendowych E, McHugh N. Genetic factors in psoriatic arthritis. Curr. Rheumatol. Rep. 7: 306-312 (2005).
Korendowych E, Owen P, Ravindran J, Carmichael C, McHugh N. The clinical and genetic associations of anti-cyclic citrullinated peptide antibodies in psoriatic arthritis. Rheumatology (Oxford) 44: 1056-1060 (2005). *
Koretz K, Momburg F, Otto HF, Moller P. Sequential induction of MHC antigens on autochthonous cells of ileum affected by Crohn's disease. Am. J. Pathol. 129: 493-502 (1987). *
Korn T, Oukka M. Dynamics of antigen-specific regulatory T-cells in the context of autoimmunity. Semin. Immunol. 19: 272-278 (2007). *
Korn T, Reddy J, Gao W, Bettelli E, Awasthi A, Petersen TR, Backstrom BT, Sobel RA, Wucherpfennig KW, Strom TB, Oukka M, Kuchroo VK. Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation. Nat. Med. 13: 423-431 (2007). *
Kornblau SM, Aycox PG, Stephens C, McCue LD, Champlin RE, Marini FC. Control of graft-versus-host disease with maintenance of the graft-versus-leukemia effect in a murine allogeneic transplant model using retrovirally transduced murine suicidal lymphocytes. Exp. Hematol. 35: 842-853 (2007).
Kort JJ, Kawamura K, Fugger L, Weissert R, Forsthuber TG. Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. J. Neuroimmunol. 173: 23-34 (2006).
Kortylewski M, Yu H. Stat3 as a potential target for cancer immunotherapy. J. Immunother. 30: 131-139 (2007).
Korzebor A, Zamani M, Nouri K, Modarressi MH. Statistical analysis of six STR loci located in MHC region in Iranian population for preimplantation genetic diagnosis. Int. J. Immunogenet. 34: 441-443 (2007). *
Kosa JP, Balla B, Kiss J, Podani J, Takacs I, Lazary A, Nagy Z, Bacsi K, Karsai A, Speer G, Lakatos P. Postmenopausal expression changes of immune system-related genes in human bone tissue. J. Clin. Immunol. 29: 761-768 (2009). *
Koskinen LL, Einarsdottir E, Korponay-Szabo IR, Kurppa K, Kaukinen K, Sistonen P, Pocsai Z, Szeles G, Adany R, Maki M, Kere J, Saavalainen P. Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations. Tissue Antigens 74: 408-416 (2009). *
Kosor E, Gagro A, Drazenovic V, Kuzman I, Jeren T, Rakusic S, Rabatic S, Markotic A, Gotovac K, Sabioncello A, Cecuk E, Kerhin-Brkljacic V, Gjenero-Margan I, Kaic B, Mlinaric-Galinovic G, Kastelan A, Dekaris D. MHC tetramers: tracking specific immunity. Acta Med. Croatica 57: 255-259 (2003).
Kotelkin A, Belyakov IM, Yang L, Berzofsky JA, Collins PL, Bukreyev A. The NS2 protein of human respiratory syncytial virus suppresses the cytotoxic T-cell response as a consequence of suppressing the type I interferon response. J. Virol. 80: 5958-5967 (2006). *
Kotenko SV, Izotova LS, Mirochnitchenko OV, Esterova E, Dickensheets H, Donnelly RP, Pestka S. Identification, cloning, and characterization of a novel soluble receptor that binds IL-22 and neutralizes its activity. J. Immunol. 166: 7096-7103 (2001). *
Krakauer T. Immune response to staphylococcal superantigens. Immunol. Res. 20: 163-173 (1999).
Kralovicova J, Hammarstrom L, Plebani A, Webster AD, Vorechovsky I. Fine-scale mapping at IGAD1 and genome-wide genetic linkage analysis implicate HLA-DQ/DR as a major susceptibility locus in selective IgA deficiency and common variable immunodeficiency. J. Immunol. 170: 2765-2775 (2003). *
Kranc KR, Taylor AM, Willcox N, Fugger L. Control of autoimmunity by 'epitope theft'. Trends Mol. Med. 11: 1-4 (2005). *
Krasowska D, Chodorowska G, Koziol-Montewka M, Ksiazek A, Buraczynska M. The -308 promoter polymorphism in the tumour necrosis factor gene in patients with lichen planus. Acta Derm. Venereol. 85: 400-403 (2005).
Krathen MS, Fiorentino D, Werth VP. Dermatomyositis. Curr. Dir. Autoimmun. 10: 313-332 (2008).
Kratz LE, Boughman JA, Needleman BW. Lack of an association between diffuse systemic sclerosis and HLA-DR1 or HLA-DR5. Dis. Markers 7: 209-213 (1989).
Kratzer A, Buchebner M, Pfeifer T, Becker TM, Uray G, Miyazaki M, Miyazaki-Anzai S, Ebner B, Chandak PG, Kadam RS, Calayir E, Rathke N, Ahammer H, Radovic B, Trauner M, Hoefler G, Kompella UB, Fauler G, Levi M, Levak-Frank S, Kostner GM, Kratky D. Synthetic LXR agonist attenuates plaque formation in apoE-deficient mice without inducing liver steatosis and hypertriglyceridemia. J. Lipid Res. 50: 312-326 (2009). *
Krauss G. Current understanding of delayed anticonvulsant hypersensitivity reactions. Epilepsy Curr. 6: 33-37 (2006).
Krawczyk M, Leimgruber E, Seguin-Estevez Q, Dunand-Sauthier I, Barras E, Reith W. Expression of RAB4B, a protein governing endocytic recycling, is co-regulated with MHC class II genes. Nucleic Acids Res. 35: 595-605 (2007). *
Krawczyk M, Masternak K, Zufferey M, Barras E, Reith W. New functions of the major histocompatibility complex class II-specific transcription factor RFXANK revealed by a high-resolution mutagenesis study. Mol. Cell. Biol. 25: 8607-8618 (2005). *
Krawczyk M, Reith W. Regulation of MHC class II expression, a unique regulatory system identified by the study of a primary immunodeficiency disease. Tissue Antigens 67: 183-197 (2006). *
Kreisman LS, Friedman JH, Neaga A, Cobb BA. Structure-function relationships with a T cell activating polysaccharide antigen using circular dichroism. Glycobiology 17: 46-55 (2007). *
Kremlev SG, Gaurnier-Hausser AL, Del Valle L, Perez-Liz G, Dimitrov S, Tuszynski G. Angiocidin promotes pro-inflammatory cytokine production and antigen presentation in multiple sclerosis. J. Neuroimmunol. 194: 132-142 (2008).
Krensky AM. The HLA system, antigen processing and presentation. Kidney Int. Suppl. 58: S2-S7 (1997).
Kriegel MA, Adam-Klages S, Gabler C, Blank N, Schiller M, Scheidig C, Kalden JR, Lorenz HM. Anti-HLA-DR-triggered monocytes mediate in vitro T cell anergy. Int. Immunol. 20: 601-613 (2008).
Krishnamoorthy G, Saxena A, Mars LT, Domingues HS, Mentele R, Ben-Nun A, Lassmann H, Dornmair K, Kurschus FC, Liblau RS, Wekerle H. Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis. Nat. Med. 15: 626-632 (2009). *
Krishnan A, Wang Z, Srivastava T, Rawal R, Manchanda P, Diamond DJ, La Rosa C. A novel approach to evaluate the immunogenicity of viral antigens of clinical importance in HLA transgenic murine models. Immunol. Lett. 120: 108-116 (2008).
Kristiansen OP, Larsen ZM, Pociot F. CTLA-4 in autoimmune diseases - a general susceptibility gene to autoimmunity? Genes Immun. 1: 170-184 (2000). *
Kroeger KM, Carville KS, Abraham LJ. The -308 tumor necrosis factor-alpha promoter polymorphism effects transcription. Mol. Immunol. 34: 391-399 (1997). *
Kroner A, Grimm A, Johannssen K, Maurer M, Wiendl H. The genetic influence of the nonclassical MHC molecule HLA-G on multiple sclerosis. Hum. Immunol. 68: 422-435 (2007).
Kroner A, Schwab N, Ip CW, Ortler S, Gobel K, Nave KA, Maurer M, Martini R, Wiendl H. Accelerated course of experimental autoimmune encephalomyelitis in PD-1-deficient central nervous system myelin mutants. Am. J. Pathol. 174: 2290-2299 (2009). *
Kruger A, Adams P, Hammer J, Bocher WO, Schneider PM, Rittner C, Hoehler T. Hepatitis B surface antigen presentation and HLA-DRB1* - lessons from twins and peptide binding studies. Clin. Exp. Immunol. 140: 325-332 (2005). *
Kruger E, Kuckelkorn U, Sijts A, Kloetzel PM. The components of the proteasome system and their role in MHC class I antigen processing. Rev. Physiol. Biochem. Pharmacol. 148: 81-104 (2003).
Kruse N, Neumann K, Schrage A, Derkow K, Schott E, Erben U, Kuhl A, Loddenkemper C, Zeitz M, Hamann A, Klugewitz K. Priming of CD4(+) T cells by liver sinusoidal endothelial cells induces CD25(low) forkhead box protein 3(-) regulatory T cells suppressing autoimmune hepatitis. Hepatology 50: 1904-1913 (2009). *
Kruskall MS, Alper CA, Awdeh Z, Yunis EJ, Marcus-Bagley D. The immune response to hepatitis B vaccine in humans: inheritance patterns in families. J. Exp. Med. 175: 495-502 (1992). *
Krzanowski JJ. Human major histocompatibility complex. Genes and diseases. J. Fla. Med. Assoc. 79: 97-99 (1992).
Kuang M, Wang S, Wu M, Ning G, Yao Z, Li L. Expression of IFNalpha-inducible genes and modulation of HLA-DR and thyroid-stimulating hormone receptors in Graves' disease. Mol. Cell. Endocrinol. Dec 13 [Epub ahead of print] (2009).
Kuczma M, Podolsky R, Garge N, Daniely D, Pacholczyk R, Ignatowicz L, Kraj P. Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset. J. Immunol. 183: 3731-3741 (2009).
Kudela P, Janjic B, Fourcade J, Castelli F, Andrade P, Kirkwood JM, El-Hefnawy T, Amicosante M, Maillere B, Zarour HM. Cross-reactive CD4+ T cells against one immunodominant tumor-derived epitope in melanoma patients. J. Immunol. 179: 7932-7940 (2007). *
Kuhn R, Lohler J, Rennick D, Rajewsky K, Muller W. Interleukin-10-deficient mice develop chronic enterocolitis. Cell 75: 263-274 (1993).
Kuhnl P, Sibrowski W, Bohm BO, Bender SW, Kalmar G, Loliger C. HLA antigen frequencies in familial Crohn's disease (CD). Beitr. Infusionsther. 26: 283-286 (1990).
Kuipers H, Muskens F, Willart M, Hijdra D, van Assema FB, Coyle AJ, Hoogsteden HC, Lambrecht BN. Contribution of the PD-1 ligands/PD-1 signaling pathway to dendritic cell-mediated CD4+ T cell activation. Eur. J. Immunol. 36: 2472-2482 (2006). *
Kuipers JG, Bialowons A, Dollmann P, Jendro MC, Wagener N, Rebmann V, Ikeda M, Huang F, Grosse-Wilde H, Yu DT, Zeidler H, Marker-Hermann E. The genetically-engineered secretory B27/Q10 chimeric molecule inhibits HLA-B27 restricted alloreactive T-lymphocytes. Clin. Exp. Rheumatol. 20: 455-462 (2002).
Kulkarni S, Martin MP, Carrington M. KIR genotyping by multiplex PCR-SSP. Methods Mol. Biol. 612: 365-375 (2010). *
Kulski JK, Gaudieri S, Inoko H, Dawkins RL. Comparison between two human endogenous retrovirus (HERV)-rich regions within the major histocompatibility complex. J. Mol. Evol. 48: 675-683 (1999). *
Kulski JK, Shigenari A, Inoko H. Polymorphic SVA retrotransposons at four loci and their association with classical HLA class I alleles in Japanese, Caucasians and African Americans. Immunogenetics Feb 20 [Epub ahead of print] (2010).
Kulski JK, Shigenari A, Shiina T, Hosomichi K, Yawata M, Inoko H. HLA-A allele associations with viral MER9-LTR nucleotide sequences at two distinct loci within the MHC alpha block. Immunogenetics 61: 257-270 (2009). *
Kulski JK, Shigenari A, Shiina T, Ota M, Hosomichi K, James I, Inoko H. Human endogenous retrovirus (HERVK9) structural polymorphism with haplotypic HLA-A allelic associations. Genetics 180: 445-457 (2008).
Kumanovics A, Fischer Lindahl K. Good copy, bad copy: choosing animal models for HLA-linked diseases. Curr. Opin. Genet. Dev. 14: 258-263 (2004). *
Kumar N, Kaur G, Tandon N, Mehra NK. Allotyping human complement factor B in Asian Indian type 1 diabetic patients. Tissue Antigens 72: 517-524 (2008). *
Kumar N, Mohanty D. MODPROPEP: a program for knowledge-based modeling of protein-peptide complexes. Nucleic Acids Res. 35: W549-W555 (2007). *
Kumar P, Vahedi-Faridi A, Saenger W, Ziegler A, Uchanska-Ziegler B. Conformational changes within the HLA-A1:MAGE-A1 complex induced by binding of a recombinant antibody fragment with TCR-like specificity. Protein Sci. 18: 37-49 (2009).
Kumar R, Eastwood AL, Brown ML, Laurie GW. Human genome search in celiac disease: mutated gliadin T-cell-like epitope in two human proteins promotes T-cell activation. J. Mol. Biol. 319: 593-602 (2002). *
Kumar R, Goswami R, Agarwal S, Israni N, Singh SK, Rani R. Association and interaction of the TNF-alpha gene with other pro- and anti-inflammatory cytokine genes and HLA genes in patients with type 1 diabetes from North India. Tissue Antigens 69: 557-567 (2007). *
Kumar V, McNerney ME. A new self: MHC-class-I-independent natural-killer-cell self-tolerance. Nat. Rev. Immunol. 5: 363-374 (2005). *
Kuo E, Maruyama T, Fernandez F, Mohanakumar T. Molecular mechanisms of chronic rejection following transplantation. Immunol. Res. 32: 179-186 (2005). *
Kuo TC, Schlissel MS. Mechanisms controlling expression of the RAG locus during lymphocyte development. Curr. Opin. Immunol. 21: 173-178 (2009).
Kuokkanen S, Sundvall M, Terwilliger JD, Tienari PJ, Wikstrom J, Holmdahl R, Pettersson U, Peltonen L. A putative vulnerability locus to multiple sclerosis maps to 5p14-p12 in a region syntenic to the murine locus Eae2. Nat. Genet. 13: 477-480 (1996). *
Kuon W, Holzhutter HG, Appel H, Grolms M, Kollnberger S, Traeder A, Henklein P, Weiss E, Thiel A, Lauster R, Bowness P, Radbruch A, Kloetzel PM, Sieper J. Identification of HLA-B27-restricted peptides from the Chlamydia trachomatis proteome with possible relevance to HLA-B27-associated diseases. J. Immunol. 167: 4738-4746 (2001). *
Kuon W, Lauster R, Bottcher U, Koroknay A, Ulbrecht M, Hartmann M, Grolms M, Ugrinovic S, Braun J, Weiss EH, Sieper J. Recognition of chlamydial antigen by HLA-B27-restricted cytotoxic T cells in HLA-B*2705 transgenic CBA (H-2k) mice. Arthritis Rheum. 40: 945-954 (1997).
Kupfer T, Beilke JN, Pham K, Buhrman J, Gill RG. "Indirect" acute islet allograft destruction in nonobese diabetic mice is independent of donor major histocompatibility complex and requires host B lymphocytes. Transplant. Proc. 40: 462-463 (2008). *
Kupfer TM, Crawford ML, Pham K, Gill RG. MHC-mismatched islet allografts are vulnerable to autoimmune recognition in vivo. J. Immunol. 175: 2309-2316 (2005). *
Kuroda T, Harada T, Wada Y, Oyanagi A, Ohfuchi Y, Murakami S, Hirose S, Hasegawa H, Nakano M, Gejyo F. Systemic lupus erythematosus in identical twins: a case report. Mod. Rheumatol. 15: 69-72 (2005).
Kuroiwa T, Iwasaki T, Imado T, Sekiguchi M, Fujimoto J, Sano H. Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease. Arthritis Res. Ther. 8: R123 (2006). *
Kusztal M, Jezior D, Weyde W, Krajewska M, Klinger M. The immune response to kidney allograft. Part I: the role of MHC antigens, antigen-presenting cells, and lymphocytes in alloantigen recognition; two-signal activation of T cells. Postepy. Hig. Med. Dosw. (Online) 61: 13-20 (2007).
Kutomi G, Tamura Y, Okuya K, Yamamoto T, Hirohashi Y, Kamiguchi K, Oura J, Saito K, Torigoe T, Ogawa S, Hirata K, Sato N. Targeting to static endosome is required for efficient cross-presentation of endoplasmic reticulum-resident oxygen-regulated protein 150-peptide complexes. J. Immunol. 183: 5861-5869 (2009).
Kwok WW, Lotshaw C, Milner EC, Knitter-Jack N, Nepom GT. Mutational analysis of the HLA-DQ3.2 insulin-dependent diabetes mellitus susceptibility gene. Proc. Natl. Acad. Sci. U.S.A. 86: 1027-1030 (1989). *
Kwon B. CD137-CD137 ligand interactions in inflammation. Immune Netw. 9: 84-89 (2009). *
Kwon H, Jun HS, Khil LY, Yoon JW. Role of CTLA-4 in the activation of single- and double-positive thymocytes. J. Immunol. 173: 6645-6653 (2004). *
Kyvelidou C, Chatzi K, Semitekolou M, Papathanassiou X, Vassiliadis S, Athanassakis I. Characterization of CD25-positive T cells during syngeneic pregnancy: production of stimulatory class II MHC molecules. Scand. J. Immunol. 70: 584-595 (2009). *
La Rosa C, Krishnan A, Longmate J, Martinez J, Manchanda P, Lacey SF, Limaye AP, Diamond DJ. Programmed death-1 expression in liver transplant recipients as a prognostic indicator of cytomegalovirus disease. J. Infect. Dis. 197: 25-33 (2008).
Laborde EA, Vanzulli S, Beigier-Bompadre M, Isturiz MA, Ruggiero RA, Fourcade MG, Catalan Pellet AC, Sozzani S, Vulcano M. Immune complexes inhibit differentiation, maturation, and function of human monocyte-derived dendritic cells. J. Immunol. 179: 673-681 (2007). *
Lafon M. Viral superantigens. Rev. Med. Interne. 21: 713-716 (2000).
Lafuse WP, Alvarez GR, Curry HM, Zwilling BS. Mycobacterium tuberculosis and Mycobacterium avium inhibit IFN-gamma-induced gene expression by TLR2-dependent and independent pathways. J. Interferon Cytokine Res. 26: 548-561 (2006).
Laham N, Rotem-Yehudar R, Shechter C, Coligan JE, Ehrlich R. Tranferrins receptor association and endosomal localization of soluble HFE are not sufficient for regulation of cellular iron homeostasis. J. Cell. Biochem. 91: 1130-1145 (2004). *
Lakhanpal S, O'Duffy JD, Homburger HA, Moore SB. Evidence for linkage of IgA deficiency with the major histocompatibility complex. Mayo Clin. Proc. 63: 461-465 (1988).
Laki J, Kiszel P, Vatay A, Blasko B, Kovacs M, Korner A, Madacsy L, Blatniczky L, Almassy Z, Szalai C, Rajczy K, Pozsonyi E, Karadi I, Fazakas A, Hosszufalusi N, Panczel P, Arason GJ, Wu YL, Zhou B, Yang Y, Yu CY, Fust G. The HLA 8.1 ancestral haplotype is strongly linked to the C allele of -429T>C promoter polymorphism of receptor of the advanced glycation end product (RAGE) gene. Haplotype-independent association of the -429C allele with high hemoglobin(A1C) levels � Mol. Immunol. 44: 648-655 (2007). *
Laki J, Laki I, Nemeth K, Ujhelyi R, Bede O, Endreffy E, Bolbas K, Gyurkovits K, Csiszer E, Solyom E, Dobra G, Halasz A, Pozsonyi E, Rajczy K, Prohaszka Z, Fekete G, Fust G. The 8.1 ancestral MHC haplotype is associated with delayed onset of colonization in cystic fibrosis. Int. Immunol. 18: 1585-1590 (2006). *
Laky K, Fleischacker C, Fowlkes BJ. TCR and Notch signaling in CD4 and CD8 T-cell development. Immunol. Rev. 209: 274-283 (2006).
Lalazar G, Preston S, Zigmond E, Ben Ya'acov A, Ilan Y. Glycolipids as immune modulatory tools. Mini Rev. Med. Chem. 6: 1249-1253 (2006).
Lambert NC, Evans PC, Hashizumi TL, Maloney S, Gooley T, Furst DE, Nelson JL. Cutting edge: persistent fetal microchimerism in T lymphocytes is associated with HLA-DQA1*0501: implications in autoimmunity. J. Immunol. 164: 5545-5548 (2000). *
Landsverk OJ, Bakke O, Gregers TF. MHC II and the endocytic pathway: regulation by invariant chain. Scand. J. Immunol. 70: 184-193 (2009). *
Lang HL, Jacobsen H, Ikemizu S, Andersson C, Harlos K, Madsen L, Hjorth P, Sondergaard L, Svejgaard A, Wucherpfennig K, Stuart DI, Bell JI, Jones EY, Fugger L. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat. Immunol. 3: 940-943 (2002). *
Lang KS, Recher M, Junt T, Navarini AA, Harris NL, Freigang S, Odermatt B, Conrad C, Ittner LM, Bauer S, Luther SA, Uematsu S, Akira S, Hengartner H, Zinkernagel RM. Toll-like receptor engagement converts T-cell autoreactivity into overt autoimmune disease. Nat. Med. 11: 138-145 (2005). *
Lange C, Doster H, Steinbach K, Kalbacher H, Scholl M, Melms A, Bischof F. Differential modulation of CNS-specific effector and regulatory T cells during tolerance induction by recombinant invariant chains in vivo. Brain Behav. Immun. 23: 861-867 (2009).
Langelaar M, Aranzamendi C, Franssen F, Van der Giessen J, Rutten V, Van der Ley P, Pinelli E. Suppression of dendritic cell maturation by Trichinella spiralis excretory/secretory products. Parasite Immunol. 10: 641-645 (2009). *
Langnickel D, Enghard P, Klein C, Undeutsch R, Hocher B, Manz R, Burmester GR, Riemekasten G. Induction of pathogenic anti-dsDNA antibodies is controlled on the level of B Cells in a non-lupus prone mouse strain. J. Clin. Immunol. 26: 86-95 (2006). *
Lanier LL, Phillips JH. Inhibitory MHC class I receptors on NK cells and T cells. Immunol. Today 17: 86-91 (1996). *
Lanning EM, Holtick U, Dickinson AM, Holler E, Gluckman E, Hromadnikova I, Middleton PG, Collin MP. Impact of mismatching CD1a, a dimorphic antigen-presenting molecule, on graft-versus-host disease after hematopoietic stem cell transplantation. Transplantation 82: 1374-1376 (2006).
Lapaque N, Hutchinson JL, Jones DC, Meresse S, Holden DW, Trowsdale J, Kelly AP. Salmonella regulates polyubiquitination and surface expression of MHC class II antigens. Proc. Natl. Acad. Sci. U.S.A. 106: 14052-14057 (2009). *
Lapaque N, Jahnke M, Trowsdale J, Kelly AP. The HLA-DRalpha chain is modified by poly-ubiquitination. J. Biol. Chem. 284: 7007-7016 (2009). *
Lapierre P, Beland K, Djilali-Saiah I, Alvarez F. Type 2 autoimmune hepatitis murine model: the influence of genetic background in disease development. J. Autoimmun. 26: 82-89 (2006).
Lara-Marquez ML, Yunis JJ, Layrisse Z, Ortega F, Carvallo-Gil E, Montagnani S, Makhatadze NJ, Pocino M, Granja C, Yunis E. Immunogenetics of atopic asthma: association of DRB1*1101 DQA1*0501 DQB1*0301 haplotype with Dermatophagoides spp.-sensitive asthma in a sample of the Venezuelan population. Clin. Exp. Allergy 29: 60-71 (1999). *
Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS. The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide. J. Immunol. 178: 2344-2351 (2007). *
Larche M. Determining MHC restriction of T-cell responses. Methods Mol. Med. 138: 57-72 (2008). *
Larizza D, Calcaterra V, Martinetti M. Autoimmune stigmata in Turner syndrome: when lacks an X chromosome. J. Autoimmun. 33: 25-30 (2009).
Larkin EA, Carman RJ, Krakauer T, Stiles BG. Staphylococcus aureus: the toxic presence of a pathogen extraordinaire. Curr. Med. Chem. 16: 4003-4019 (2009).
Larranaga CL, Ampuero SL, Luchsinger VF, Carrion FA, Aguilar NV, Morales PR, Palomino MA, Tapia LF, Avendano LF. Impaired immune response in severe human lower tract respiratory infection by respiratory syncytial virus. Pediatr. Infect. Dis. J. Sep 4 [Epub ahead of print] (2009).
Larsen AE, Cameron-Smith D, Crowe TC. Conjugated linoleic acid suppresses myogenic gene expression in a model of human muscle cell inflammation. J. Nutr. 138: 12-16 (2008). *
Larsen CE, Alper CA. The genetics of HLA-associated disease. Curr. Opin. Immunol. 16: 660-667 (2004).
Larsen MH, Thomas VF. HLA-G polymorphism in relation to expression, function and disease. Hum. Immunol. 70: 1026-1034 (2009).
Larsen MV, Lundegaard C, Lamberth K, Buus S, Lund O, Nielsen M. Large-scale validation of methods for cytotoxic T-lymphocyte epitope prediction. BMC Bioinformatics 8: 424 (2007). *
Lascorz J, Burkhardt H, Huffmeier U, Bohm B, Schurmeyer-Horst F, Lohmann J, Stander M, Wendler J, Kelsch R, Baumann C, Kuster W, Traupe H, Reis A. Lack of genetic association of the three more common polymorphisms of CARD15 with psoriatic arthritis and psoriasis in a German cohort. Ann. Rheum. Dis. 64: 951-954 (2005). *
Lau AW, Biester S, Cornall RJ, Forrester JV. Lipopolysaccharide-activated IL-10-secreting dendritic cells suppress experimental autoimmune uveoretinitis by MHCII-dependent activation of CD62L-expressing regulatory T cells. J. Immunol. 180: 3889-3899 (2008). *
Laub R, Dorsch M, Meyer D, Ermann J, Hedrich HJ, Emmrich F. A multiple transgenic mouse model with a partially humanized activation pathway for helper T cell responses. J. Immunol. Methods 246: 37-50 (2000). *
Laugel B, Price DA, Milicic A, Sewell AK. CD8 exerts differential effects on the deployment of cytotoxic T lymphocyte effector functions. Eur. J. Immunol. 37: 905-913 (2007). *
Laughlin E, Burke G, Pugliese A, Falk B, Nepom G. Recurrence of autoreactive antigen-specific CD4+ T cells in autoimmune diabetes after pancreas transplantation. Clin. Immunol. 128: 23-30 (2008). *
Laughlin EM, Miller JD, James E, Fillos D, Ibegbu CC, Mittler RS, Akondy R, Kwok W, Ahmed R, Nepom G. Antigen-specific CD4+ T cells recognize epitopes of protective antigen following AVA vaccination. Infect. Immun. 75: 1852-1860 (2007). *
Laukens D, Vos MD. Genetics of spondyloarthropathies and inflammatory bowel disease: searching for common susceptibility factors. Curr. Rheumatol. Rev. 4: 12-22 (2008).
Lautenschlager I, Halme L, Hockerstedt K, Krogerus L, Taskinen E. Cytomegalovirus infection of the liver transplant: virological, histological, immunological, and clinical observations. Transpl. Infect. Dis. 8: 21-30 (2006). *
Lavado-Valenzuela R, Benavides M, Carabantes F, Alonso A, Caballero A. MHC class I chain-related gene A transmembrane polymorphism in Spanish women with breast cancer. Tissue Antigens 74: 46-49 (2009). *
Laval SH, Timms A, Edwards S, Bradbury L, Brophy S, Milicic A, Rubin L, Siminovitch KA, Weeks DE, Calin A, Wordsworth BP, Brown MA. Whole-genome screening in ankylosing spondylitis: evidence of non-MHC genetic-susceptibility loci. Am. J. Hum. Genet. 68: 918-926 (2001). *
Lavezzari G, Roche KW. Constitutive endocytosis of the metabotropic glutamate receptor mGluR7 is clathrin-independent. Neuropharmacology 52: 100-107 (2007). *
Lawman S, Mauri C, Jury EC, Cook HT, Ehrenstein MR. Atorvastatin inhibits autoreactive B cell activation and delays lupus development in New Zealand Black/White F1 mice. J. Immunol. 173: 7641-7646 (2004). *
Layrisse Z, White C, Gunczler P, Gafaro Valera L, Arias S, Yunis EJ, Alper CA, Awdeh ZL. Sharing of MHC haplotypes among apparently unrelated patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Immunogenetics 25: 99-103 (1987).
Layton DS, Bean AG, Dodge NM, Strom AD, Sandrin MS, Ierino FL. Differential cytokine expression and regulation of human anti-pig xenogeneic responses by modified porcine dendritic cells. Xenotransplantation 15: 257-267 (2008).
Lazarski CA, Chaves FA, Jenks SA, Wu S, Richards KA, Weaver JM, Sant AJ. The kinetic stability of MHC class II:peptide complexes is a key parameter that dictates immunodominance. Immunity 23: 29-40 (2005). *
Lazarski CA, Chaves FA, Sant AJ. The impact of DM on MHC class II-restricted antigen presentation can be altered by manipulation of MHC-peptide kinetic stability. J. Exp. Med. 203: 1319-1328 (2006). *
Lazoura E, Lodding J, Farrugia W, Ramsland PA, Stevens J, Wilson IA, Pietersz GA, Apostolopoulos V. Enhanced major histocompatibility complex class I binding and immune responses through anchor modification of the non-canonical tumour-associated mucin 1-8 peptide. Immunology 119: 306-316 (2006). *
Le Panse R, Cizeron-Clairac G, Bismuth J, Berrih-Aknin S. Microarrays reveal distinct gene signatures in the thymus of seropositive and seronegative myasthenia gravis patients and the role of CC chemokine ligand 21 in thymic hyperplasia. J. Immunol. 177: 7868-7879 (2006). *
Le Poole IC, Luiten RM. Autoimmune etiology of generalized vitiligo. Curr. Dir. Autoimmun. 10: 227-243 (2008).
Lebbink RJ, Meyaard L. Non-MHC ligands for inhibitory immune receptors: novel insights and implications for immune regulation. Mol. Immunol. 44: 2153-2164 (2007). *
Leblanc DM, Barousse MM, Fidel PL Jr. Role for dendritic cells in immunoregulation during experimental vaginal candidiasis. Infect. Immun. 74: 3213-3221 (2006). *
Lee HC, Ikegami H, Fujisawa T, Ogihara T, Park SW, Chung YS, Park JO, Lee EJ, Lim SK, Kim KR, Huh KB, Kim YS, Lee DS, Kim DH. Role of HLA class II alleles in Korean patients with IDDM. Diabetes Res. Clin. Pract. 31: 9-15 (1996).
Lee HK, Iwasaki A. Autophagy and antiviral immunity. Curr. Opin. Immunol. 20: 23-29 (2008).
Lee HK, Mattei LM, Steinberg BE, Alberts P, Lee YH, Chervonsky A, Mizushima N, Grinstein S, Iwasaki A. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity Feb 17 [Epub ahead of print] (2010).
Lee HS, Lee AT, Criswell LA, Seldin MF, Amos CI, Carulli JP, Navarrete C, Remmers EF, Kastner DL, Plenge RM, Li W, Gregersen PK. Several regions in the major histocompatibility complex confer risk for anti-CCP-antibody positive rheumatoid arthritis, independent of the DRB1 locus. Mol. Med. 14: 293-300 (2008). *
Lee JS, Lee JC, Lee CM, Jung ID, Jeong YI, Seong EY, Chung HY, Park YM. Outer membrane protein A of Acinetobacter baumannii induces differentiation of CD4(+) T cells toward a Th1 polarizing phenotype through the activation of dendritic cells. Biochem. Pharmacol. 74: 86-97 (2007). *
Lee JS, Shin SJ, Collins MT, Jung ID, Jeong YI, Lee CM, Shin YK, Kim D, Park YM. Mycobacterium avium subsp. paratuberculosis fibronectin attachment protein activates dendritic cells and induces a Th1 polarization. Infect. Immun. 77: 2979-2988 (2009). *
Lee KW, Lee Y, Kim DS, Kwon HJ. Direct role of NF-kappaB activation in Toll-like receptor-triggered HLA-DRA expression. Eur. J. Immunol. 36: 1254-1266 (2006). *
Lee SH, Matsuyama T, Logalbo P, Silver J, Winchester RJ. Ia antigens and susceptibility to rheumatoid arthritis. Clin. Rheum. Dis. 11: 645-664 (1985).
Lee SJ, Qin H, Benveniste EN. The IFN-gamma-induced transcriptional program of the CIITA gene is inhibited by statins. Eur. J. Immunol. 38: 2325-2336 (2008). *
Lee SO, Cho K, Cho S, Kim I, Oh C, Ahn K. Protein disulphide isomerase is required for signal peptide peptidase-mediated protein degradation. EMBO J. Nov 26 [Epub ahead of print] (2009). *
Lee SR, Pharr GT, Cooksey AM, McCarthy FM, Boyd BL, Pinchuk LM. Differential detergent fractionation for non-electrophoretic bovine peripheral blood monocyte proteomics reveals proteins involved in professional antigen presentation. Dev. Comp. Immunol. 30: 1070-1083 (2006).
Lee SU, Grigorian A, Pawling J, Chen IJ, Gao G, Mozaffar T, McKerlie C, Demetriou M. N-glycan processing deficiency promotes spontaneous inflammatory demyelination and neurodegeneration. J. Biol. Chem. 282: 33725-33734 (2007). *
Lee TH, Cho HK, Cho YH, Lee MG. Development of an effective method for dendritic cell immunotherapy of mouse melanoma. Scand. J. Immunol. 70: 85-92 (2009). *
Lee YS, Sakurai M, Imai Y, Horinouchi T, Goto T, Yamada A. Induction of heat shock proteins in a rat composite tissue allotransplantation model of acute rejection. Plast. Reconstr. Surg. 118: 29-40 (2006).
Leelayuwat C, Pinelli M, Dawkins RL. Clustering of diverse replicated sequences in the MHC. Evidence for en bloc duplication. J. Immunol. 155: 692-698 (1995).
Leelayuwat C, Townend DC, Degli-Esposti MA, Abraham LJ, Dawkins RL. A new polymorphic and multicopy MHC gene family related to nonmammalian class I. Immunogenetics 40: 339-351 (1994).
Lefranc MP. IMGT, the international ImMunoGeneTics information system(R): a standardized approach for immunogenetics and immunoinformatics. Immunome Res. 1: 3 (2005). *
Lefranc MP, Giudicelli V, Ginestoux C, Jabado-Michaloud J, Folch G, Bellahcene F, Wu Y, Gemrot E, Brochet X, Lane J, Regnier L, Ehrenmann F, Lefranc G, Duroux P. IMGT(R), the international ImMunoGeneTics information system(R). Nucleic Acids Res. 37: D1006-D1012 (2009). *
Lefranc MP, Giudicelli V, Kaas Q, Duprat E, Jabado-Michaloud J, Scaviner D, Ginestoux C, Clement O, Chaume D, Lefranc G. IMGT, the international ImMunoGeneTics information system(R). Nucleic Acids Res. 33: D593-D597 (2005). *
Leguern C. Tolerogenic property of MHC class I and class II molecules: lessons from a gene therapy approach. Front. Biosci. 12: 3133-3139 (2007).
Lehner B, Semple JI, Brown SE, Counsell D, Campbell RD, Sanderson CM. Analysis of a high-throughput yeast two-hybrid system and its use to predict the function of intracellular proteins encoded within the human MHC class III region. Genomics 83: 153-167 (2004). *
LeibundGut-Landmann S, Waldburger JM, Krawczyk M, Otten LA, Suter T, Fontana A, Acha-Orbea H, Reith W. Mini-review: specificity and expression of CIITA, the master regulator of MHC class II genes. Eur. J. Immunol. 34: 1513-1525 (2004). *
Leinders-Zufall T, Brennan P, Widmayer P, S PC, Maul-Pavicic A, Jager M, Li XH, Breer H, Zufall F, Boehm T. MHC class I peptides as chemosensory signals in the vomeronasal organ. Science 306: 1033-1037 (2004). *
Leithauser F, Meinhardt-Krajina T, Fink K, Wotschke B, Moller P, Reimann J. Foxp3-expressing CD103+ regulatory T cells accumulate in dendritic cell aggregates of the colonic mucosa in murine transfer colitis. Am. J. Pathol. 168: 1898-1909 (2006). *
Lelouard H, Henri S, de Bovis B, Mugnier B, Chollat-Namy A, Malissen B, Meresse S, Gorvel JP. Pathogenic bacteria and dead cells are internalized by a unique subset of Peyer's patch dendritic cells that express lysozyme. Gastroenterology 138: 173-184.e3 (2010). *
Lemin AJ, Saleki K, van Lith M, Benham AM. Activation of the unfolded protein response and alternative splicing of ATF6alpha in HLA-B27 positive lymphocytes. FEBS Lett. 581: 1819-1824 (2007). *
Leng C, Gries M, Ziegler J, Lokshin A, Mascagni P, Lentzsch S, Mapara MY. Reduction of graft-versus-host disease by histone deacetylase inhibitor suberonylanilide hydroxamic acid is associated with modulation of inflammatory cytokine milieu and involves inhibition of STAT1. Exp. Hematol. 34: 776-787 (2006). *
Leng Q, Ge Q, Nguyen T, Eisen HN, Chen J. Stage-dependent reactivity of thymocytes to self-peptide-MHC complexes. Proc. Natl. Acad. Sci. U.S.A. 104: 5038-5043 (2007). *
Lengagne R, Graff-Dubois S, Garcette M, Renia L, Kato M, Guillet JG, Engelhard VH, Avril MF, Abastado JP, Prevost-Blondel A. Distinct role for CD8 T cells toward cutaneous tumors and visceral metastases. J. Immunol. 180: 130-137 (2008). *
Lengerke C, Kim K, Lerou P, Daley GQ. Differentiation potential of histocompatible parthenogenetic embryonic stem cells. Ann. N. Y. Acad. Sci. 1106: 209-218 (2007).
Lengyel CS, Willis LJ, Mann P, Baker D, Kortemme T, Strong RK, McFarland BJ. Mutations designed to destabilize the receptor-bound conformation increase MICA-NKG2D association rate and affinity. J. Biol. Chem. 282: 30658-30666 (2007). *
Lenz TL, Becker S. Simple approach to reduce PCR artefact formation leads to reliable genotyping of MHC and other highly polymorphic loci - implications for evolutionary analysis. Gene 427: 117-123 (2008). *
Leon MP, Bassendine MF, Wilson JL, Ali S, Thick M, Kirby JA. Immunogenicity of biliary epithelium: investigation of antigen presentation to CD4+ T cells. Hepatology 24: 561-567 (1996).
Leon MP, Kirby JA, Gibbs P, Burt AD, Bassendine MF. Immunogenicity of biliary epithelial cells: study of the expression of B7 molecules. J. Hepatol. 22: 591-595 (1995). *
Leslie S, Donnelly P, McVean G. A statistical method for predicting classical HLA alleles from SNP data. Am. J. Hum. Genet. 82: 48-56 (2008). *
Lessard MD, Alley TL, Proctor JL, Galvin N, Vogler CA, Soper BW. Attenuation of murine lysosomal storage disease by allogeneic neonatal bone marrow transplantation using costimulatory blockade and donor lymphocyte infusion without myeloablation. Clin. Immunol. 119: 166-179 (2006). *
Lester SE, McLure C, Williamson J, Bardy P, Rischmueller M, Dawkins RL. Epistasis between MHC and the RCA alpha block in primary Sjogren's syndrome. Ann. Rheum. Dis. 67: 849-854 (2008). *
Lesueur F, Lefevre C, Has C, Guilloud-Bataille M, Oudot T, Mahe E, Lahfa M, Mansouri S, Mosharraf-Olmolk H, Sobel E, Heath S, Lathrop M, Dizier MH, Prud'homme JF, Fischer J. Confirmation of psoriasis susceptibility loci on chromosome 6p21 and 20p13 in French families. J. Invest. Dermatol. 127: 1403-1409 (2007). *
Letsch A, Keilholz U, Kern F, Asemissen AM, Thiel E, Scheibenbogen C. Specific central memory T cells in the bone marrow of patients immunized against tyrosinase peptides. J. Immunother. 29: 201-207 (2006).
Leung DY, Travers JB, Norris DA. The role of superantigens in skin disease. J. Invest. Dermatol. 105: 37S-42S (1995).
Levin D, Dipaolo RJ, Brinster C, Revilleza MJ, Boyd LF, Teyton L, Natarajan K, Mage MG, Shevach EM, Margulies DH. Availability of autoantigenic epitopes controls phenotype, severity, and penetrance in TCR Tg autoimmune gastritis. Eur. J. Immunol. 38: 3339-3353 (2008). *
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat. Rev. Immunol. 7: 767-777 (2007). *
Levisetti MG, Lewis DM, Suri A, Unanue ER. Weak proinsulin peptide-major histocompatibility complexes are targeted in autoimmune diabetes in mice. Diabetes 57: 1852-1860 (2008). *
Levy EM, Bianchini M, Von Euw EM, Barrio MM, Bravo AI, Furman D, Domenichini E, Macagno C, Pinsky V, Zucchini C, Valvassori L, Mordoh J. Human leukocyte antigen-E protein is overexpressed in primary human colorectal cancer. Int. J. Oncol. 32: 633-641 (2008). *
Lewis EC, Shapiro L, Bowers OJ, Dinarello CA. alpha1-Antitrypsin monotherapy prolongs islet allograft survival in mice. Proc. Natl. Acad. Sci. U.S.A. 102: 12153-12158 (2005). *
Li CF, He XH, Teng Q, Jiang ZF. Association of HLA-A, B, and DR haplotypes with genotype in Chinese children with systemic lupus erythematosus. Zhonghua Er Ke Za Zhi 41: 422-425 (2003).
Li F, Yang D, Wang Y, Liu B, Deng Y, Wang L, Shang X, Tong W, Ni B, Wu Y. Identification and modification of an HLA-A*0201-restricted cytotoxic T lymphocyte epitope from Ran antigen. Cancer Immunol. Immunother. 58: 2039-2049 (2009).
Li GQ, Lu LZ, Wang DQ, Shen JD, Tao ZR, Zhao AZ, Yuan AP. Advance in association studies of major histocompatibility complex (MHC) gene polymorphisms with traits of resistance against infectious disease in chickens. Yi Chuan 28: 893-898 (2006).
Li H, Ciric B, Yang J, Xu H, Fitzgerald DC, Elbehi M, Fonseca-Kelly Z, Yu S, Zhang GX, Rostami A. Intravenous tolerance modulates macrophage classical activation and antigen presentation in experimental autoimmune encephalomyelitis. J. Neuroimmunol. 208: 54-60 (2009).
Li H, Llera A, Malchiodi EL, Mariuzza RA. The structural basis of T cell activation by superantigens. Annu. Rev. Immunol. 17: 435-466 (1999). *
Li H, Zhan T, Li C, Liu M, Wang QK. Repression of MHC class I transcription by HPV16E7 through interaction with a putative RXRbeta motif and NF-kappaB cytoplasmic sequestration. Biochem. Biophys. Res. Commun. 388: 383-388 (2009). *
Li H, Zhao Y, Guo Y, Li Z, Eisele L, Mourad W. Zinc induces dimerization of the class II major histocompatibility complex molecule that leads to cooperative binding to a superantigen. J. Biol. Chem. 282: 5991-6000 (2007). *
Li HS, Ligons DL, Rose NR. Genetic complexity of autoimmune myocarditis. Autoimmun. Rev. 7: 168-173 (2008).
Li J, Melenhorst J, Hensel N, Rezvani K, Sconocchia G, Kilical Y, Hou J, Curfman B, Major E, Barrett AJ. T-cell responses to peptide fragments of the BK virus T antigen: implications for cross-reactivity of immune response to JC virus. J. Gen. Virol. 87: 2951-2960 (2006). *
Li J, Qian CN, Zeng YX. Regulatory T cells and EBV associated malignancies. Int. Immunopharmacol. 9: 590-592 (2009).
Li JM, Gorechlad J, Larsen CP, Waller EK. Apoptotic donor leukocytes limit mixed-chimerism induced by CD40-CD154 blockade in allogeneic bone marrow transplantation. Biol. Blood Marrow Transplant. 12: 1239-1249 (2006).
Li L, Yi Z, Wang B, Tisch R. Suppression of ongoing T cell-mediated autoimmunity by peptide-MHC class II dimer vaccination. J. Immunol. 183: 4809-4816 (2009).
Li M, Wang Y, Guo R, Bai Y, Yu Z. Glucocorticoids impair microglia ability to induce T cell proliferation and Th1 polarization. Immunol. Lett. 109: 129-137 (2007).
Li N, Zhao M, Hilario-Vargas J, Prisayanh P, Warren S, Diaz LA, Roopenian DC, Liu Z. Complete FcRn dependence for intravenous Ig therapy in autoimmune skin blistering diseases. J. Clin. Invest. 115: 3440-3450 (2005). *
Li P, McDermott G, Strong RK. Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D. Immunity 16: 77-86 (2002). *
Li P, Morris DL, Willcox BE, Steinle A, Spies T, Strong RK. Complex structure of the activating immunoreceptor NKG2D and its MHC class I-like ligand MICA. Nat. Immunol. 2: 443-451 (2001). *
Li S, Yao X, Liu H, Li J, Fan B. Prediction of T-cell epitopes based on least squares support vector machines and amino acid properties. Anal. Chim. Acta 584: 37-42 (2007).
Li WM, Liu W, Gao C, Zhou BG, Yang SS, Wang Z, Zhang RH, Gan RT, Kong YH, Li Y. Antigen-specific tolerance induced by IL-10 gene modified immature dendritic cells in experimental autoimmune myocarditis in rats. Chin. Med. J. (Engl.) 119: 1646-1652 (2006). *
Li XD, Zou X, Zhang Y, Lu N, Wan FR, Zhao SM, Li XL, Jiang H. The study of peripheral blood mononuclear cell MHC I and MHC II gene mRNA expression in acute graft rejection. Transplant. Proc. 38: 3055-3057 (2006). *
Li XL, Zhang D, Knight D, Odaka Y, Glass J, Mathis JM, Zhang QJ. Priming of immune responses against transporter associated with antigen processing (TAP)-deficient tumours: tumour direct priming. Immunology 128: 420-428 (2009). *
Li Y, Ayata G, Baker SP, Banner BF. Cholangitis: a histologic classification based on patterns of injury in liver biopsies. Pathol. Res. Pract. 201: 565-572 (2005).
Li Y, Chu N, Rostami A, Zhang GX. Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro and in vivo. J. Immunol. 177: 1679-1688 (2006). *
Li Y, Hofmann M, Wang Q, Teng L, Chlewicki LK, Pircher H, Mariuzza RA. Structure of natural killer cell receptor KLRG1 bound to E-cadherin reveals basis for MHC-independent missing self recognition. Immunity 31: 35-46 (2009). *
Li Y, Huang Y, Lue J, Quandt JA, Martin R, Mariuzza RA. Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule. EMBO J. 24: 2968-2979 (2005). *
Li Y, Li H, Martin R, Mariuzza RA. Structural basis for the binding of an immunodominant peptide from myelin basic protein in different registers by two HLA-DR2 proteins. J. Mol. Biol. 304: 177-188 (2000). *
Li Y, Thapa P, Hawke D, Kondo Y, Furukawa K, Furukawa K, Hsu FF, Adlercreutz D, Weadge J, Palcic MM, Wang PG, Levery SB, Zhou D. Immunologic glycosphingolipidomics and NKT cell development in mouse thymus. J. Proteome Res. 8: 2740-2751 (2009). *
Li Y, Xia B, Lu M, Ge L, Zhang X. MICB0106 gene polymorphism is associated with ulcerative colitis in central China. Int. J. Colorectal Dis. Aug 7 [Epub ahead of print] (2009). *
Li Y, Xia B, Lu M, Ge LQ, Li C, Luo Y, Jiang T. An association between MICB 0106 allele and ulcerative colitis in Chinese Han in Hubei province. Zhonghua Nei Ke Za Zhi 47: 213-216 (2008).
Li Y, Zhu X, Huang Y, Xiong H. Mutational analysis of the binding of staphylococcal enterotoxin D to the T cell receptor Vbeta chain and major histocompatibility complex class II. Immunol. Lett. 105: 55-60 (2006).
Lian Y, Yue J, Han M, Liu J, Liu L. Analysis of the association between BTNL2 polymorphism and tuberculosis in Chinese Han population. Infect. Genet. Evol. Feb 19 [Epub ahead of print] (2010).
Liang G, Yang L, Chen Z, Mei H, Shu M, Li Z. A set of new amino acid descriptors applied in prediction of MHC class I binding peptides. Eur. J. Med. Chem. 44: 1144-1154 (2009). *
Liang S, Ristich V, Arase H, Dausset J, Carosella ED, Horuzsko A. Modulation of dendritic cell differentiation by HLA-G and ILT4 requires the IL-6-STAT3 signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 105: 8357-8362 (2008). *
Liao F, Li Z, Wang Y, Shi B, Gong Z, Cheng X. Porphyromonas gingivalis may play an important role in the pathogenesis of periodontitis-associated rheumatoid arthritis. Med. Hypotheses 72: 732-735 (2009).
Liblau R. Glatiramer acetate for the treatment of multiple sclerosis: evidence for a dual anti-inflammatory and neuroprotective role. J. Neurol. Sci. 287 Suppl. 1: S17-S23 (2009).
Lie BA, Thorsby E. Several genes in the extended human MHC contribute to predisposition to autoimmune diseases. Curr. Opin. Immunol. 17: 526-531 (2005).
Lie BA, Todd JA, Pociot F, Nerup J, Akselsen HE, Joner G, Dahl-Jorgensen K, Ronningen KS, Thorsby E, Undlien DE. The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am. J. Hum. Genet. 64: 793-800 (1999). *
Lie BA, Viken MK, Akselsen HE, Flam ST, Pociot F, Nerup J, Kockum I, Cambon-Thomsen A, Thorsby E, Undlien DE. Association analysis in type 1 diabetes of the PRSS16 gene encoding a thymus-specific serine protease. Hum. Immunol. 68: 592-598 (2007).
Lie HC, Simmons LW, Rhodes G. Does genetic diversity predict health in humans? PLoS One 4: e6391 (2009). *
Lilienfeld BG, Crew MD, Forte P, Baumann BC, Seebach JD. Transgenic expression of HLA-E single chain trimer protects porcine endothelial cells against human natural killer cell-mediated cytotoxicity. Xenotransplantation 14: 126-134 (2007).
Lin CC, Tu CF, Yen MC, Chen MC, Hsieh WJ, Chang WC, Chang WT, Lai MD. Inhibitor of heat-shock protein 90 enhances the antitumor effect of DNA vaccine targeting clients of heat-shock protein. Mol. Ther. 15: 404-410 (2007). *
Lin HH, Ray S, Tongchusak S, Reinherz EL, Brusic V. Evaluation of MHC class I peptide binding prediction servers: applications for vaccine research. BMC Immunol. 9: 8 (2008). *
Lin HH, Zhang GL, Tongchusak S, Reinherz EL, Brusic V. Evaluation of MHC-II peptide binding prediction servers: applications for vaccine research. BMC Bioinformatics 9 Suppl. 12: S22 (2008). *
Lin JT, Kitzmiller TJ, Cates JM, Gorham JD. MHC-independent genetic regulation of liver damage in a mouse model of autoimmune hepatocellular injury. Lab. Invest. 85: 550-561 (2005). *
Lin ML, Zhan Y, Villadangos JA, Lew AM. The cell biology of cross-presentation and the role of dendritic cell subsets. Immunol. Cell Biol. 86: 353-362 (2008). *
Lin TH. Predicting the MHC-peptide affinity using some interactive-type molecular descriptors and QSAR models. Methods Mol. Biol. 409: 247-260 (2007).
Lin XP, Almqvist N, Telemo E. Human small intestinal epithelial cells constitutively express the key elements for antigen processing and the production of exosomes. Blood Cells Mol. Dis. 35: 122-128 (2005).
Lin YJ, Wan L, Wu JY, Sheu JJ, Lin CW, Lan YC, Lai CH, Hung CH, Tsai Y, Tsai CH, Lin TH, Lin JG, Hsueh KC, Huang YM, Chang JS, Tsai FJ. HLA-E gene polymorphism associated with susceptibility to Kawasaki disease and formation of coronary artery aneurysms. Arthritis Rheum. 60: 604-610 (2009). *
Lincoln MR, Montpetit A, Cader MZ, Saarela J, Dyment DA, Tiislar M, Ferretti V, Tienari PJ, Sadovnick AD, Peltonen L, Ebers GC, Hudson TJ. A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis. Nat. Genet. 37: 1108-1112 (2005). *
Lincoln MR, Ramagopalan SV, Chao MJ, Herrera BM, Deluca GC, Orton SM, Dyment DA, Sadovnick AD, Ebers GC. Epistasis among HLA-DRB1, HLA-DQA1, and HLA-DQB1 loci determines multiple sclerosis susceptibility. Proc. Natl. Acad. Sci. U.S.A. 106: 7542-7547 (2009). *
Lind EF, Ahonen CL, Wasiuk A, Kosaka Y, Becher B, Bennett KA, Noelle RJ. Dendritic cells require the NF-kappaB2 pathway for cross-pesentation of soluble antigens. J. Immunol. 181: 354-363 (2008). *
Lindholm E, Melander O, Almgren P, Berglund G, Agardh CD, Groop L, Orho-Melander M. Polymorphism in the MHC2TA gene is associated with features of the metabolic syndrome and cardiovascular mortality. PLoS ONE 1: e64 (2006). *
Lindor K. What is the role of major histocompatibility complex expression in cholestasis? Gastroenterology 102: 1429-1430 (1992).
Lindqvist AK, Alarcon-Riquelme ME. The genetics of systemic lupus erythematosus. Scand. J. Immunol. 50: 562-571 (1999). *
Lindqvist AK, Nakken B, Sundler M, Kjellen P, Jonsson R, Holmdahl R, Skarstein K. Influence on spontaneous tissue inflammation by the major histocompatibility complex region in the nonobese diabetic mouse. Scand. J. Immunol. 61: 119-127 (2005). *
Lindstedt R, Monk N, Lombardi G, Lechler R. Amino acid substitutions in the putative MHC class II "dimer of dimers" interface inhibit CD4+ T cell activation. J. Immunol. 166: 800-808 (2001). *
Ling S, Lai A, Borschukova O, Pumpens P, Holoshitz J. Activation of nitric oxide signaling by the rheumatoid arthritis shared epitope. Arthritis Rheum. 54: 3423-3432 (2006). *
Linga-Reddy MV, Gunnarsson I, Svenungsson E, Sturfelt G, Jonsen A, Truedsson L, Nordmark G, Ronnblom L, Alarcon-Riquelme ME. A polymorphic variant in the MHC2TA gene is not associated with systemic lupus erythematosus. Tissue Antigens 70: 412-414 (2007). *
Lio D, Balistreri CR, Colonna-Romano G, Motta M, Franceschi C, Malaguarnera M, Candore G, Caruso C. Association between the MHC class I gene HFE polymorphisms and longevity: a study in Sicilian population. Genes Immun. 3: 20-24 (2002). *
Lio D, D'Anna C, Leone F, Curro MF, Candore G, Caruso C. Hypothesis: interleukin-5 production impairment can be a key point in the pathogenesis of the MHC-linked selective IgA deficiency. Autoimmunity 27: 185-188 (1998).
Lipozencic J, Ljubojevic S. Langerhans' cells in dermatology. Arh. Hig. Rada. Toksikol. 55: 167-174 (2004).
Lipsitch M, Bergstrom CT, Antia R. Effect of human leukocyte antigen heterozygosity on infectious disease outcome: the need for allele-specific measures. BMC Med. Genet. 4: 2 (2003). *
Lissina A, Ladell K, Skowera A, Clement M, Edwards E, Seggewiss R, van den Berg HA, Gostick E, Gallagher K, Jones E, Melenhorst JJ, Godkin AJ, Peakman M, Price DA, Sewell AK, Wooldridge L. Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers. J. Immunol. Methods 340: 11-24 (2009). *
Listi F, Candore G, Balistreri CR, Grimaldi MP, Orlando V, Vasto S, Colonna-Romano G, Lio D, Licastro F, Franceschi C, Caruso C. Association between the HLA-A2 allele and Alzheimer disease. Rejuvenation Res. 9: 99-101 (2006).
Liston A, Nutsch KM, Farr AG, Lund JM, Rasmussen JP, Koni PA, Rudensky AY. Differentiation of regulatory Foxp3+ T cells in the thymic cortex. Proc. Natl. Acad. Sci. U.S.A. 105: 11903-11908 (2008). *
Liston A, Rudensky AY. Thymic development and peripheral homeostasis of regulatory T cells. Curr. Opin. Immunol. 19: 176-185 (2007).
Liu H, Liu K, Wang J, Ma RZ. A BAC clone-based physical map of ovine major histocompatibility complex. Genomics 88: 88-95 (2006). *
Liu KJ, Leu SJ, Su CH, Chiang BL, Chen YL, Lee YL. Administration of polysaccharides from Antrodia camphorata modulates dendritic cell function and alleviates allergen-induced T helper type 2 responses in a mouse model of asthma. Immunology Aug 17 [Epub ahead of print] (2009). *
Liu LY, Mathur SK, Sedgwick JB, Jarjour NN, Busse WW, Kelly EA. Human airway and peripheral blood eosinophils enhance Th1 and Th2 cytokine secretion. Allergy 61: 589-597 (2006). *
Liu Q, Shu X, Sun A, Sun Q, Zhang C, An H, Liu J, Cao X. Plant-derived small molecule albaconol suppresses LPS-triggered proinflammatory cytokine production and antigen presentation of dendritic cells by impairing NF-kappaB activation. Int. Immunopharmacol. 8: 1103-1111 (2008).
Liu QJ, Gao B. Manipulation of MHC-I/TCR interaction for immune therapy. Cell. Mol. Immunol. 5: 171-182 (2008). *
Liu W, Li WM, Sun NL. Relationship between HLA-DQA1 polymorphism and genetic susceptibility to idiopathic dilated cardiomyopathy. Chin. Med. J. (Engl.) 117: 1449-1452 (2004).
Liu W, Li WM, Sun NL. Association of HLA-DQ with idiopathic dilated cardiomyopathy in a Northern Chinese Han population. Cell. Mol. Immunol. 1: 311-314 (2004). *
Liu W, Li WM, Sun NL. HLA-DQA1, -DQB1 polymorphism and genetic susceptibility to idiopathic dilated cardiomyopathy in Hans of northern China. Ann. Hum. Genet. 69: 382-388 (2005).
Liu W, Li WM, Yang SS, Gao C, Li SJ, Li Y, Kong YH, Gan RT. Association of HLA class II DRB1, DPA1 and DPB1 polymorphism with genetic susceptibility to idiopathic dilated cardiomyopathy in Chinese Han nationality. Autoimmunity 39: 461-467 (2006).
Liu W, Meng X, Xu Q, Flower DR, Li T. Quantitative prediction of mouse class I MHC peptide binding affinity using support vector machine regression (SVR) models. BMC Bioinformatics 7: 182 (2006). *
Liu X, Fu Y, Liu Z, Lin B, Xie Y, Liu Y, Xu Y, Lin J, Fan X, Dong M, Zeng K, Wu CI, Xu A. An ancient balanced polymorphism in a regulatory region of human major histocompatibility complex is retained in Chinese minorities but lost worldwide. Am. J. Hum. Genet. 78: 393-400 (2006). *
Liu X, Ye L, Christianson GJ, Yang JQ, Roopenian DC, Zhu X. NF-kappaB signaling regulates functional expression of the MHC class I-related neonatal Fc receptor for IgG via intronic binding sequences. J. Immunol. 179: 2999-3011 (2007). *
Liu Y, Bando Y, Vargas-Lowy D, Elyaman W, Khoury SJ, Huang T, Reif K, Chitnis T. CD200R1 agonist attenuates mechanisms of chronic disease in a murine model of multiple sclerosis. J. Neurosci. 30: 2025-2038 (2010).
Liu Y, Helms C, Liao W, Zaba LC, Duan S, Gardner J, Wise C, Miner A, Malloy MJ, Pullinger CR, Kane JP, Saccone S, Worthington J, Bruce I, Kwok PY, Menter A, Krueger J, Barton A, Saccone NL, Bowcock AM. A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci. PLoS Genet. 4: e1000041 (2008). *
Liu Y, Li HJ, Qiu XT, Guo HW, Li YH, Zhang Q. Molecular characterization, expression and mapping of porcine LMP2 and MECL-1 genes. DNA Seq. 18: 257-264 (2007).
Liu Y, Li P, Lu J, Xiong W, Oger J, Tetzlaff W, Cynader M. Bilirubin possesses powerful immunomodulatory activity and suppresses experimental autoimmune encephalomyelitis. J. Immunol. 181: 1887-1897 (2008). *
Liu Y, Teige I, Birnir B, Issazadeh-Navikas S. Neuron-mediated generation of regulatory T cells from encephalitogenic T cells suppresses EAE. Nat. Med. 12: 518-525 (2006). *
Liu Z, Zheng X, Wang J, Wang E. Molecular analysis of thymopentin binding to HLA-DR molecules. PLoS ONE 2: e1348 (2007). *
Lizee G, Basha G, Jefferies WA. Tails of wonder: endocytic-sorting motifs key for exogenous antigen presentation. Trends Immunol. 26: 141-149 (2005). *
Llanos MC, Soto SL, Sabugo SF, Bastias ChMJ, Salazar AL, Aguillon GJC, Cuchacovich TM. The influence of -238 and -308 TNF alpha polymorphisms on the pathogenesis and response to treatment in rheumatoid arthritis. Rev. Med. Chil. 133: 1089-1095 (2005).
Lleo A, Invernizzi P, Selmi C, Coppel RL, Alpini G, Podda M, Mackay IR, Gershwin ME. Autophagy: highlighting a novel player in the autoimmunity scenario. J. Autoimmun. 29: 61-68 (2007).
Lo FS, Lee YJ, Huang CY, Lin CH, Chang SC, Dang CW, Liu HF. Polymorphism in the transmembrane region of the major histocompatibility complex class I chain-related gene A: association of five GCT repetitions with Graves' disease in children. Thyroid 13: 839-843 (2003).
Lo WL, Felix NJ, Walters JJ, Rohrs H, Gross ML, Allen PM. An endogenous peptide positively selects and augments the activation and survival of peripheral CD4(+) T cells. Nat. Immunol. 10: 1155-1161 (2009). *
Loane DJ, Deighan BF, Clarke RM, Griffin RJ, Lynch AM, Lynch MA. Interleukin-4 mediates the neuroprotective effects of rosiglitazone in the aged brain. Neurobiol. Aging 30: 920-931 (2009).
Lobeck H, Hopf U, Gill C, Pohl C, Neuhaus P. Primary biliary cirrhosis - cellular mechanisms and role of enterobacterial antigens. Verh. Dtsch. Ges. Pathol. 80: 267-271 (1996).
Loewenthal R, Slomov Y, Gonzalez-Escribano MF, Goldberg I, Korostishevsky M, Brenner S, Nunez-Roldan A, Conejo-Mir JS, Gazit E. Common ancestral origin of pemphigus vulgaris in Jews and Spaniards: a study using microsatellite markers. Tissue Antigens 63: 326-334 (2004). *
Logunova NN, Viret C, Pobezinsky LA, Miller SA, Kazansky DB, Sundberg JP, Chervonsky AV. Restricted MHC-peptide repertoire predisposes to autoimmunity. J. Exp. Med. 202: 73-84 (2005). *
Lohse AW, Dinkelmann M, Kimmig M, Herkel J, Meyer zum Buschenfelde KH. Estimation of the frequency of self-reactive T cells in health and inflammatory diseases by limiting dilution analysis and single cell cloning. J. Autoimmun. 9: 667-675 (1996).
Loisel DA, Rockman MV, Wray GA, Altmann J, Alberts SC. Ancient polymorphism and functional variation in the primate MHC-DQA1 5' cis-regulatory region. Proc. Natl. Acad. Sci. U.S.A. 103: 16331-16336 (2006). *
Long BR, Ndhlovu LC, Oksenberg JR, Lanier LL, Hecht FM, Nixon DF, Barbour JD. Conferral of enhanced natural killer cell function by KIR3DS1 in early human immunodeficiency virus type 1 infection. J. Virol. 82: 4785-4792 (2008). *
Long EO, Colonna M, Lanier LL. Inhibitory MHC class I receptors on NK and T cells: a standard nomenclature. Immunol. Today 17: 100 (1996). *
Lopes CT, Gallo AP, Palma PV, Cury PM, Bueno V. Skin allograft survival and analysis of renal parameters after FTY720 + tacrolimus treatment in mice. Transplant. Proc. 40: 856-860 (2008).
Lopez de Castro JA. HLA-B27 and the pathogenesis of spondyloarthropathies. Immunol. Lett. 108: 27-33 (2007).
Lopez P, Gutierrez C, Suarez A. IFNalpha treatment generates antigen-presenting cellsinsensitive to atorvastatin inhibition of MHC-II expression. Clin. Immunol. 129: 350-359 (2008). *
Lopez-Arbesu R, Ballina-Garcia FJ, Alperi-Lopez M, Lopez-Soto A, Rodriguez-Rodero S, Martinez-Borra J, Lopez-Vazquez A, Fernandez-Morera JL, Riestra-Noriega JL, Queiro-Silva R, Quinones-Lombrana A, Lopez-Larrea C, Gonzalez S. MHC class I chain-related gene B (MICB) is associated with rheumatoid arthritis susceptibility. Rheumatology (Oxford) 46: 426-430 (2007). *
Lopez-Botet M, Angulo A, Guma M. Natural killer cell receptors for major histocompatibility complex class I and related molecules in cytomegalovirus infection. Tissue Antigens 63: 195-203 (2004). *
Lopez-Botet M, Bellon T, Llano M, Navarro F, Garcia P, de Miguel M. Paired inhibitory and triggering NK cell receptors for HLA class I molecules. Hum. Immunol. 61: 7-17 (2000).
Lopez-Botet M, Moretta L, Strominger J. NK-cell receptors and recognition of MHC class I molecules. Immunol. Today 17: 212-214 (1996). *
Lopez-Escamez JA, Vilchez JR, Soto-Varela A, Santos-Perez S, Perez-Garrigues H, Aran I, Lopez-Nevot MA. HLA-DRB1*1101 allele may be associated with bilateral Meniere's disease in Southern European population. Otol. Neurotol. 28: 891-895 (2007).
Lopez-Larrea C, Gonzalez S, Martinez-Borra J. The role of HLA-B27 polymorphism and molecular mimicry in spondylarthropathy. Mol. Med. Today 4: 540-549 (1998).
Lopez-Vazquez A, Fuentes D, Rodrigo L, Gonzalez S, Moreno M, Fernandez E, Martinez-Borra J, Lopez-Larrea C. MHC class I region plays a role in the development of diverse clinical forms of celiac disease in a Saharawi population. Am. J. Gastroenterol. 99: 662-667 (2004). *
Lopez-Vazquez A, Rodrigo L, Fuentes D, Riestra S, Bousono C, Garcia-Fernandez S, Martinez-Borra J, Gonzalez S, Lopez-Larrea C. MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201. Gut 50: 336-340 (2002). *
Loser K, Brzoska T, Oji V, Auriemma M, Voskort M, Kupas V, Klenner L, Mensing C, Hauschild A, Beissert S, Luger TA. The neuropeptide alpha-melanocyte-stimulating hormone is critically involved in the development of cytotoxic CD8 T cells in mice and humans. PLoS One 5: e8958 (2010). *
Loser K, Sturm A, Voskort M, Kupas V, Balkow S, Auriemma M, Sternemann C, Dignass AU, Luger TA, Beissert S. Galectin-2 suppresses contact allergy by inducing apoptosis in activated CD8+ T cells. J. Immunol. 182: 5419-5429 (2009).
Lotem M, Zhao Y, Riley J, Hwu P, Morgan RA, Rosenberg SA, Parkhurst MR. Presentation of tumor antigens by dendritic cells genetically modified with viral and nonviral vectors. J. Immunother. 29: 616-627 (2006).
Loureiro J, Lilley BN, Spooner E, Noriega V, Tortorella D, Ploegh HL. Signal peptide peptidase is required for dislocation from the endoplasmic reticulum. Nature 441: 894-897 (2006). *
Loureiro J, Ploegh HL. Antigen presentation and the ubiquitin-proteasome system in host-pathogen interactions. Adv. Immunol. 92: 225-305 (2006).
Love VA, Grabie N, Duramad P, Stavrakis G, Sharpe A, Lichtman A. CTLA-4 ablation and interleukin-12 driven differentiation synergistically augment cardiac pathogenicity of cytotoxic T lymphocytes. Circ. Res. 101: 248-257 (2007). *
Lozanoska-Ochser B, Barone F, Pitzalis C, Peakman M. Atorvastatin fails to prevent the development of autoimmune diabetes despite inhibition of pathogenic beta-cell-specific CD8 T-cells. Diabetes 55: 1004-1010 (2006). *
Lu L, Cantor H. Generation and regulation of CD8(+) regulatory T cells. Cell. Mol. Immunol. 5: 401-406 (2008). *
Lu L, Ikizawa K, Hu D, Werneck MB, Wucherpfennig KW, Cantor H. Regulation of activated CD4(+) T cells by NK cells via the Qa-1-NKG2A inhibitory pathway. Immunity 26: 593-604 (2007). *
Lu L, Werneck MB, Cantor H. The immunoregulatory effects of Qa-1. Immunol. Rev. 212: 51-59 (2006). *
Lu LY, Ding WZ, Fici D, Deulofeut R, Cheng HH, Cheu CC, Sung PK, Schur PH, Fraser PA. Molecular analysis of major histocompatibility complex allelic associations with systemic lupus erythematosus in Taiwan. Arthritis Rheum. 40: 1138-1145 (1997).
Lu M, Xia B, Ge L, Li Y, Zhao J, Chen F, Zhou F, Zhang X, Tan J. Role of major histocompatibility complex class I-related molecules A*A5.1 allele in ulcerative colitis in Chinese patients. Immunology 128: e230-e236 (2009). *
Lu M, Xia B, Li J, Ye M, Zhang X, Tan Q. MICB microsatellite polymorphism is associated with ulcerative colitis in Chinese population. Clin. Immunol. 120: 199-204 (2006). *
Lu MC, Yang KL, Tung CH, Huang KY, Yu HC, Liu SQ, Lai NS. Higher LPS-stimulated TNF-alpha mRNA levels in peripheral blood mononuclear cells from Chinese ankylosing spondylitis patients with -308(G/A) polymorphism in promoter region of tumor necrosis factor: association with distinct A33/B58/Cw10 haplotypes. Rheumatol. Int. 29: 189-195 (2008). *
Lu X, Kavanagh DG, Hill AB. Cellular and molecular requirements for association of the murine cytomegalovirus protein m4/gp34 with major histocompatibility complex class I molecules. J. Virol. 80: 6048-6055 (2006). *
Lucas D, Campillo JA, Lopez-Hernandez R, Martinez-Garcia P, Lopez-Sanchez M, Botella C, Salgado G, Minguela A, Alvarez-Lopez MR, Muro M. Allelic diversity of MICA gene and MICA/HLA-B haplotypic variation in a population of the Murcia region in southeastern Spain. Hum. Immunol. 69: 655-660 (2008).
Luci C, Tomasello E. Natural killer cells: detectors of stress. Int. J. Biochem. Cell Biol. 40: 2335-2340 (2008). *
Luckashenak N, Schroeder S, Endt K, Schmidt D, Mahnke K, Bachmann MF, Marconi P, Deeg CA, Brocker T. Constitutive crosspresentation of tissue antigens by dendritic cells controls CD8+ T cell tolerance in vivo. Immunity 28: 521-532 (2008). *
Luckow B, Joergensen J, Chilla S, Li JP, Henger A, Kiss E, Wieczorek G, Roth L, Hartmann N, Hoffmann R, Kretzler M, Nelson PJ, De Lema GP, Maier H, Wurst W, Balling R, Pfeffer K, Grone HJ, Schlondorff D, Zerwes HG. Reduced intragraft mRNA expression of matrix metalloproteinases Mmp3, Mmp12, Mmp13 and Adam8, and diminished transplant arteriosclerosis in Ccr5-deficient mice. Eur. J. Immunol. 34: 2568-2578 (2004). *
Luna E, Postol E, Caldas C, Mundel LR, Porto G, Iwai LK, Ho PL, Kalil J, Coelho V. Diversity of physiological cell reactivity to heat shock protein 60 in different mouse strains. Cell Stress Chaperones 12: 112-122 (2007). *
Lund AK, Goens MB, Nunez BA, Walker MK. Characterizing the role of endothelin-1 in the progression of cardiac hypertrophy in aryl hydrocarbon receptor (AhR) null mice. Toxicol. Appl. Pharmacol. 212: 127-135 (2006). *
Lundberg K, Venables PJ. Epitope spreading in animal models: array of hope in rheumatoid arthritis and multiple sclerosis. Arthritis Res. Ther. 10: 122 (2008). *
Lunde E, Lauvrak V, Rasmussen IB, Schjetne KW, Thompson KM, Michaelsen TE, Brekke OH, Sollid LM, Bogen B, Sandlie I. Troybodies and pepbodies. Biochem. Soc. Trans. 30: 500-506 (2002). *
Lundegaard C, Lamberth K, Harndahl M, Buus S, Lund O, Nielsen M. NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11. Nucleic Acids Res. 36: W509-W512 (2008). *
Lundegaard C, Lund O, Kesmir C, Brunak S, Nielsen M. Modeling the adaptive immune system: predictions and simulations. Bioinformatics 23: 3265-3275 (2007). *
Lundqvist A, Su S, Rao S, Childs R. Cutting edge: bortezomib-treated tumors sensitized to NK cell apoptosis paradoxically acquire resistance to antigen-specific T cells. J. Immunol. Dec 21 [Epub ahead of print] (2009).
Lunemann A, Lunemann JD, Roberts S, Messmer B, da Silva RB, Raine CS, Munz C. Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J. Immunol. 181: 6170-6177 (2008). *
Lunemann JD, Munz C. Autophagy in CD4+ T-cell immunity and tolerance. Cell Death Differ. 16: 79-86 (2009). *
Lunemann JD, Schmidt J, Dalakas MC, Munz C. Macroautophagy as a pathomechanism in sporadic inclusion body myositis. Autophagy 3: 384-386 (2007). *
Lunemann JD, Schmidt J, Schmid D, Barthel K, Wrede A, Dalakas MC, Munz C. beta-Amyloid is a substrate of autophagy in sporadic inclusion body myositis. Ann. Neurol. 61: 476-483 (2007).
Luo P, Reed BD, Tsang TC, Harris DT, Flavell RA. A self-augmenting gene expression cassette for enhanced and sustained transgene expression in the presence of proinflammatory cytokines. DNA Cell Biol. 25: 659-667 (2006).
Luthra-Guptasarma M, Singh B. HLA-B27 lacking associated beta2-microglobulin rearranges to auto-display or cross-display residues 169-181: a novel molecular mechanism for spondyloarthropathies. FEBS Lett. 575: 1-8 (2004). *
Lutz W. Pas de deux: natural killer receptors and MHC class I ligands in primates. Curr. Genomics 8: 51-57 (2007).
Lynch AM, Loane DJ, Minogue AM, Clarke RM, Kilroy D, Nally RE, Roche OJ, O'Connell F, Lynch MA. Eicosapentaenoic acid confers neuroprotection in the amyloid-beta challenged aged hippocampus. Neurobiol. Aging 28: 845-855 (2007).
Lynch S, Santos SG, Campbell EC, Nimmo AM, Botting C, Prescott A, Antoniou AN, Powis SJ. Novel MHC class I structures on exosomes. J. Immunol. 183: 1884-1891 (2009).
Ma SL, Tang NL, Tam CW, Lui VW, Suen EW, Chiu HF, Lam LC. Association between HLA-A alleles and Alzheimer's disease in a Southern Chinese community. Dement. Geriatr. Cogn. Disord. 26: 391-397 (2008).
Ma Z, Chen F, Madaio MP, Cohen PL, Eisenberg RA. Modulation of autoimmunity by TLR9 in the chronic graft-vs-host model of systemic lupus erythematosus. J. Immunol. 177: 7444-7450 (2006). *
Ma Z, Finkel TH. T cell receptor triggering by force. Trends Immunol. 31: 1-6 (2010). *
Maalej A, Makni H, Ayadi F, Bellassoued M, Jouida J, Bouguacha N, Abid M, Ayadi H. A full genome screening in a large Tunisian family affected with thyroid autoimmune disorders. Genes Immun. 2: 71-75 (2001). *
Macagno A, Molteni M, Rinaldi A, Bertoni F, Lanzavecchia A, Rossetti C, Sallusto F. A cyanobacterial LPS antagonist prevents endotoxin shock and blocks sustained TLR4 stimulation required for cytokine expression. J. Exp. Med. 203: 1481-1492 (2006). *
Macaluso F, Nothnagel M, Parwez Q, Petrasch-Parwez E, Bechara FG, Epplen JT, Hoffjan S. Polymorphisms in NACHT-LRR (NLR) genes in atopic dermatitis. Exp. Dermatol. 16: 692-698 (2007). *
Macatonia SE, Hsieh CS, Murphy KM, O'Garra A. Dendritic cells and macrophages are required for Th1 development of CD4+ T cells from alpha beta TCR transgenic mice: IL-12 substitution for macrophages to stimulate IFN-gamma production is IFN-gamma-dependent. Int. Immunol. 5: 1119-1128 (1993).
Maccalli C, Di Cristanziano V, Fodale V, Corsi D, D'Agostino G, Petrangeli V, Laurenti L, Guida S, Mazzocchi A, Arienti F, Perrone MP, Castelli C, Rivoltini L, Zagonel V, Tartaglia M, Parmiani G, Belardelli F. Induction of both CD8+ and CD4+ T-cell-mediated responses in colorectal cancer patients by colon antigen-1. Clin. Cancer Res. 14: 7292-7303 (2008). *
Macconi D, Chiabrando C, Schiarea S, Aiello S, Cassis L, Gagliardini E, Noris M, Buelli S, Zoja C, Corna D, Mele C, Fanelli R, Remuzzi G, Benigni A. Proteasomal processing of albumin by renal dendritic cells generates antigenic peptides. J. Am. Soc. Nephrol. 20: 123-130 (2009).
Macedo GC, Magnani DM, Carvalho NB, Bruna-Romero O, Gazzinelli RT, Oliveira SC. Central role of MyD88-dependent dendritic cell maturation and proinflammatory cytokine production to control Brucella abortus infection. J. Immunol. 180: 1080-1087 (2008). *
Mach B, Steimle V, Martinez-Soria E, Reith W. Regulation of MHC class II genes: lessons from a disease. Annu. Rev. Immunol. 14: 301-331 (1996). *
Macintyre CR. New developments in BCG vaccine: implications for tuberculosis control. Epidemiol. Infect. 135: 177-180 (2007).
Mack M, Bender K, Schneider PM. Detection of retroviral antisense transcripts and promoter activity of the HERV-K(C4) insertion in the MHC class III region. Immunogenetics 56: 321-332 (2004). *
Mack SJ, Sanchez-Mazas A, Single RM, Meyer D, Hill J, Dron HA, Jani AJ, Thomson G, Erlich HA. Population samples and genotyping technology. Tissue Antigens 69 Suppl. 1: 188-191 (2007). *
Mackay IR, Gershwin ME. Primary biliary cirrhosis: current knowledge, perspectives, and future directions. Semin. Liver Dis. 9: 149-157 (1989).
Mackay IR, Tait BD. HLA associations with autoimmune-type chronic active hepatitis: identification of B8-DRw3 haplotype by family studies. Gastroenterology 79: 95-98 (1980).
MacKay K, Eyre S, Myerscough A, Milicic A, Barton A, Laval S, Barrett J, Lee D, White S, John S, Brown MA, Bell J, Silman A, Ollier W, Wordsworth P, Worthington J. Whole-genome linkage analysis of rheumatoid arthritis susceptibility loci in 252 affected sibling pairs in the United Kingdom. Arthritis Rheum. 46: 632-639 (2002). *
Mackelprang R, Livingston RJ, Eberle MA, Carlson CS, Yi Q, Akey JM, Nickerson DA. Sequence diversity, natural selection and linkage disequilibrium in the human T cell receptor alpha/delta locus. Hum. Genet. 119: 255-266 (2006). *
Macleod M, Kwakkenbos MJ, Crawford A, Brown S, Stockinger B, Schepers K, Schumacher T, Gray D. CD4 memory T cells survive and proliferate but fail to differentiate in the absence of CD40. J. Exp. Med. 203: 897-906 (2006). *
Maddur MS, Kaveri SV, Bayry J. Basophils as antigen presenting cells. Trends Immunol. 31: 45-48 (2010). *
Madsen LS, Andersson EC, Jansson L, krogsgaard M, Andersen CB, Engberg J, Strominger JL, Svejgaard A, Hjorth JP, Holmdahl R, Wucherpfennig KW, Fugger L. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nat. Genet. 23: 343-347 (1999). *
Maehr R, Mintern JD, Herman AE, Lennon-Dumenil AM, Mathis D, Benoist C, Ploegh HL. Cathepsin L is essential for onset of autoimmune diabetes in NOD mice. J. Clin. Invest. 115: 2934-2943 (2005). *
Maemura K, Yanagawa Y, Obata K, Dohi T, Egashira Y, Shibayama Y, Watanabe M. Antigen-presenting cells expressing glutamate decarboxylase 67 were identified as epithelial cells in glutamate decarboxylase 67-GFP knock-in mouse thymus. Tissue Antigens 67: 198-206 (2006). *
Magez S, Radwanska M, Drennan M, Fick L, Baral TN, Brombacher F, Baetselier PD. Interferon-gamma and nitric oxide in combination with antibodies are key protective host immune factors during Trypanosoma congolense Tc13 infections. J. Infect. Dis. 193: 1575-1583 (2006). *
Maggio-Price L, Treuting P, Zeng W, Tsang M, Bielefeldt-Ohmann H, Iritani BM. Helicobacter infection is required for inflammation and colon cancer in smad3-deficient mice. Cancer Res. 66: 828-838 (2006). *
Maggiore G, Sciveres M. Autoimmune hepatitis: a childhood disease. Current Pediatric Reviews 1: 73-90 (2005). *
Magliocca JF, Held IK, Odorico JS. Undifferentiated murine embryonic stem cells cannot induce portal tolerance but may possess immune privilege secondary to reduced major histocompatibility complex antigen expression. Stem Cells Dev. 15: 707-717 (2006).
Maglione PJ, Xu J, Casadevall A, Chan J. Fc gamma receptors regulate immune activation and susceptibility during Mycobacterium tuberculosis infection. J. Immunol. 180: 3329-3338 (2008). *
Magnusson FC, Liblau RS, von Boehmer H, Pittet MJ, Lee JW, Turley SJ, Khazaie K. Direct presentation of antigen by lymph node stromal cells protects against CD8 T-cell-mediated intestinal autoimmunity. Gastroenterology 134: 1028-1037 (2008). *
Maher AC, Fu MH, Isfort RJ, Varbanov AR, Qu XA, Tarnopolsky MA. Sex differences in global mRNA content of human skeletal muscle. PLoS One 4: e6335 (2009). *
Mahler M, Bristol IJ, Leiter EH, Workman AE, Birkenmeier EH, Elson CO, Sundberg JP. Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis. Am. J. Physiol. 274: G544-G551 (1998). *
Mahmutefendic H, Blagojevic G, Kucic N, Lucin P. Constitutive internalization of murine MHC class I molecules. J. Cell. Physiol. 210: 445-455 (2006). *
Mahnke K, Ring S, Johnson TS, Schallenberg S, Schonfeld K, Storn V, Bedke T, Enk AH. Induction of immunosuppressive functions of dendritic cells in vivo by CD4+CD25+ regulatory T cells: role of B7-H3 expression and antigen presentation. Eur. J. Immunol. 37: 2117-2126 (2007). *
Mahon RN, Rojas RE, Fulton SA, Franko J, Harding CV, Boom WH. Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T cell activation by interfering with proximal T cell receptor signaling. Infect. Immun. 77: 4574-4583 (2009). *
Maia MH, Peixoto Rde L, de Lima CP, Magalhaes M, Sena L, Costa Pdo S, Barbosa FB, de Oliveira LF, Romero M, Silva CN, dos Santos EJ. Predisposition to idiopathic thrombocytopenic purpura maps close to the major histocompatibility complex class I chain-related gene A. Hum. Immunol. 70: 179-183 (2009).
Majewska M, Szczepanik M. The role of Toll-like receptors (TLR) in innate and adaptive immune responses and their function in immune response regulation. Postepy. Hig. Med. Dosw. (Online) 60: 52-63 (2006).
Majewska M, Zajac K, Kubera M, Bryniarski K, Ptak M, Basta-Kaim A, Ksiazek L, Ptak W, Lason W, Szczepanik M. Effect of ovoalbumin on the survival of an H-Y incompatible skin graft in C57BL/6 mice. Pharmacol. Rep. 58: 439-442 (2006). *
Majlessi L, Simsova M, Jarvis Z, Brodin P, Rojas MJ, Bauche C, Nouze C, Ladant D, Cole ST, Sebo P, Leclerc C. An increase in antimycobacterial Th1-cell responses by prime-boost protocols of immunization does not enhance protection against tuberculosis. Infect. Immun. 74: 2128-2137 (2006). *
Major AS, Joyce S, Van Kaer L. Lipid metabolism, atherogenesis and CD1-restricted antigen presentation. Trends Mol. Med. 12: 270-278 (2006). *
Majumder P, Gomez JA, Boss JM. The human major histocompatibility complex class II HLA-DRB1 and HLA-DQA1 genes are separated by a CTCF binding enhancer-blocking element. J. Biol. Chem. 281: 18435-18443 (2006). *
Makhatadze NJ, Franco MT, Layrisse Z. HLA class I and class II allele and haplotype distribution in the Venezuelan population. Hum. Immunol. 55: 53-58 (1997).
Makrigiannis AP, Anderson SK. Regulation of natural killer cell function. Cancer Biol. Ther. 2: 610-616 (2003). *
Makrigiannis AP, Patel D, Goulet ML, Dewar K, Anderson SK. Direct sequence comparison of two divergent class I MHC natural killer cell receptor haplotypes. Genes Immun. 6: 71-83 (2005). *
Makwana M, Jones LL, Cuthill D, Heuer H, Bohatschek M, Hristova M, Friedrichsen S, Ormsby I, Bueringer D, Koppius A, Bauer K, Doetschman T, Raivich G. Endogenous transforming growth factor beta1 suppresses inflammation and promotes survival in adult CNS. J. Neurosci. 27: 11201-11213 (2007).
Malanga D, Barba P, Harris PE, Maffei A, Del Pozzo G. The active translation of MHCII mRNA during dendritic cells maturation supplies new molecules to the cell surface pool. Cell. Immunol. 246: 75-80 (2007). *
Malarkannan S. The balancing act: inhibitory Ly49 regulate NKG2D-mediated NK cell functions. Semin. Immunol. 18: 186-192 (2006). *
Malissen B. Deflecting a canonical antiviral T cell response. Immunity 30: 169-171 (2009). *
Malkki M, Gooley T, Horowitz M, Petersdorf EW; on behalf of the IHWG HCT Component. MHC class I, II, and III microsatellite marker matching and survival in unrelated donor hematopoietic cell transplantation. Tissue Antigens 69 Suppl. 1: 46-49 (2007). *
Mallal S, Nolan D, Witt C, Masel G, Martin AM, Moore C, Sayer D, Castley A, Mamotte C, Maxwell D, James I, Christiansen FT. Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. Lancet 359: 727-732 (2002). *
Mallegol J, Van Niel G, Lebreton C, Lepelletier Y, Candalh C, Dugave C, Heath JK, Raposo G, Cerf-Bensussan N, Heyman M. T84-intestinal epithelial exosomes bear MHC class II/peptide complexes potentiating antigen presentation by dendritic cells. Gastroenterology 132: 1866-1876 (2007). *
Mallone R, Nepom GT. Targeting T lymphocytes for immune monitoring and intervention in autoimmune diabetes. Am. J. Ther. 12: 534-550 (2005).
Mamyrova G, O'hanlon TP, Monroe JB, Carrick DM, Malley JD, Adams S, Reed AM, Shamim EA, James-Newton L, Miller FW, Rider LG. Immunogenetic risk and protective factors for juvenile dermatomyositis in Caucasians. Arthritis Rheum. 54: 3979-3987 (2006). *
Mandelboim O, Kent S, Davis DM, Wilson SB, Okazaki T, Jackson R, Hafler D, Strominger JL. Natural killer activating receptors trigger interferon gamma secretion from T cells and natural killer cells. Proc. Natl. Acad. Sci. U.S.A. 95: 3798-3803 (1998). *
Mandik-Nayak L, Allen PM. Initiation of an autoimmune response: insights from a transgenic model of rheumatoid arthritis. Immunol. Res. 32: 5-14 (2005). *
Mangalam A, Luckey D, Basal E, Behrens M, Rodriguez M, David C. HLA-DQ6 (DQB1*0601)-restricted T cells protect against experimental autoimmune encephalomyelitis in HLA-DR3.DQ6 double-transgenic mice by generating anti-inflammatory IFN-gamma. J. Immunol. 180: 7747-7756 (2008). *
Mangalam A, Luckey D, Basal E, Jackson M, Smart M, Rodriguez M, David C. HLA-DQ8 (DQB1*0302)-restricted Th17 cells exacerbate experimental autoimmune encephalomyelitis in HLA-DR3-transgenic mice. J. Immunol. 182: 5131-5139 (2009).
Mangalam A, Rodriguez M, David C. Role of MHC class II expressing CD4(+) T cells in proteolipid protein(91-110)-induced EAE in HLA-DR3 transgenic mice. Eur. J. Immunol. 36: 3356-3370 (2006). *
Mangalam A, Rodriguez M, David C. A new humanized HLA transgenic mouse model of multiple sclerosis expressing class II on mouse CD4 T cells. Ann. N. Y. Acad. Sci. 1103: 112-117 (2007). *
Mangalam AK, Khare M, Krco C, Rodriguez M, David C. Identification of T cell epitopes on human proteolipid protein and induction of experimental autoimmune encephalomyelitis in HLA class II-transgenic mice. Eur. J. Immunol. 34: 280-290 (2004). *
Mangalam AK, Rajagopalan G, Taneja V, David CS. HLA class II transgenic mice mimic human inflammatory diseases. Adv. Immunol. 97C: 65-147 (2008).
Manku H, Graham DS, Vyse TJ. Association of the co-stimulator OX40L with systemic lupus erythematosus. J. Mol. Med. 87: 229-234 (2009). *
Mannie MD, Abbott DJ. A fusion protein consisting of IL-16 and the encephalitogenic peptide of myelin basic protein constitutes an antigen-specific tolerogenic vaccine that inhibits experimental autoimmune encephalomyelitis. J. Immunol. 179: 1458-1465 (2007). *
Mannion A, Stevens FM, McCarthy CF, Grimes-O'Cearbhaill H, Killeen AA. Extended major histocompatibility complex haplotypes in celiac patients in the west of Ireland. Am. J. Med. Genet. 45: 373-377 (1993).
Manns MP. Round table: classification of autoimmune liver diseases and diagnostic criteria. Subgroups of autoimmune hepatitis are important. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 56-57 (2004). *
Manns MP, Bremm A, Schneider PM, Notghi A, Gerken G, Prager-Eberle M, Stradmann-Bellinghausen B, Meyer zum Buschenfelde KH, Rittner C. HLA DRw8 and complement C4 deficiency as risk factors in primary biliary cirrhosis. Gastroenterology 101: 1367-1373 (1991).
Manns MP, Kruger M. Immunogenetics of chronic liver diseases. Gastroenterology 106: 1676-1697 (1994).
Manns MP, Wiegand J. Novel approaches to the treatment of autoimmune hepatitis. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, pp. 67-70 (2004). *
Manolios N, Dunckley H, Chivers T, Brooks P, Englert H. Immunogenetic analysis of 5 families with multicase occurrence of scleroderma and/or related variants. J. Rheumatol. 22: 85-92 (1995).
Mansfield LS, Patterson JS, Fierro BR, Murphy AJ, Rathinam VA, Kopper JJ, Barbu NI, Onifade TJ, Bell JA. Genetic background of IL-10(-/-) mice alters host-pathogen interactions with Campylobacter jejuni and influences disease phenotype. Microb. Pathog. 45: 241-257 (2008). *
Mao XJ, Zhang XM, Zhang HL, Quezada HC, Mix E, Yang X, Winblad B, Adem A, Zhu J. TNF-alpha receptor 1 deficiency reduces antigen-presenting capacity of Schwann cells and ameliorates experimental autoimmune neuritis in mice. Neurosci. Lett. Dec 23 [Epub ahead of print] (2009).
Marcilla M, Lopez de Castro JA. Peptides: the cornerstone of HLA-B27 biology and pathogenetic role in spondyloarthritis. Tissue Antigens 71: 495-506 (2008). *
Maree AF, Santamaria P, Edelstein-Keshet L. Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy. Int. Immunol. 18: 1067-1077 (2006). *
Mareeva T, Martinez-Hackert E, Sykulev Y. How a T cell receptor-like antibody recognizes major histocompatibility complex-bound peptide. J. Biol. Chem. 283: 29053-29059 (2008). *
Margolles-Clark E, Jacques-Silva MC, Ganesan L, Umland O, Kenyon NS, Ricordi C, Berggren PO, Buchwald P. Suramin inhibits the CD40-CD154 costimulatory interaction: a possible mechanism for immunosuppressive effects. Biochem. Pharmacol. 77: 1236-1245 (2009).
Margolles-Clark E, Umland O, Kenyon NS, Ricordi C, Buchwald P. Small-molecule costimulatory blockade: organic dye inhibitors of the CD40-CD154 interaction. J. Mol. Med. 87: 1133-1143 (2009). *
Margulies DH. Home schooling of NK cells. Immunity 30: 313-315 (2009). *
Mariani SM. Genes and autoimmune diseases - a complex inheritance. MedGenMed. 6: 18 (2004). *
Marin-Esteban V, Falk K, Rotzschke O. "Chemical analogues" of HLA-DM can induce a peptide-receptive state in HLA-DR molecules. J. Biol. Chem. 279: 50684-50690 (2004). *
Markel G, Achdout H, Katz G, Ling KL, Salio M, Gruda R, Gazit R, Mizrahi S, Hanna J, Gonen-Gross T, Arnon TI, Lieberman N, Stren N, Nachmias B, Blumberg RS, Steuer G, Blau H, Cerundolo V, Mussaffi H, Mandelboim O. Biological function of the soluble CEACAM1 protein and implications in TAP2-deficient patients. Eur. J. Immunol. 34: 2138-2148 (2004). *
Markovic-Plese S. Degenerate T-cell receptor recognition, autoreactive cells, and the autoimmune response in multiple sclerosis. Neuroscientist 15: 225-231 (2009).
Marleau AM, Sarvetnick N. T cell homeostasis in tolerance and immunity. J. Leukoc. Biol. 78: 575-584 (2005). *
Marques CP, Cheeran MC, Palmquist JM, Hu S, Urban SL, Lokensgard JR. Prolonged microglial cell activation and lymphocyte infiltration following experimental herpes encephalitis. J. Immunol. 181: 6417-6426 (2008). *
Marrack P, Kappler J. Control of T cell viability. Annu. Rev. Immunol. 22: 765-787 (2004). *
Marrack P, Kushnir E, Kappler J. A maternally inherited superantigen encoded by a mammary tumour virus. Nature 349: 524-526 (1991). *
Marrack P, Scott-Browne JP, Dai S, Gapin L, Kappler JW. Evolutionarily conserved amino acids that control TCR-MHC interaction. Annu. Rev. Immunol. 26: 171-203 (2008). *
Marrero I, Huffman D, Kalil J, Sercarz EE, Coelho V. TAP1 mice present oligoclonal BV-BJ expansions following the rejection of grafts bearing self antigens. Immunology 118: 461-471 (2006). *
Marrosu MG, Murru MR, Costa G, Murru R, Muntoni F, Cucca F. DRB1-DQA1-DQB1 loci and multiple sclerosis predisposition in the Sardinian population. Hum. Mol. Genet. 7: 1235-1237 (1998). *
Marrosu MG, Murru R, Murru MR, Costa G, Zavattari P, Whalen M, Cocco E, Mancosu C, Schirru L, Solla E, Fadda E, Melis C, Porru I, Rolesu M, Cucca F. Dissection of the HLA association with multiple sclerosis in the founder isolated population of Sardinia. Hum. Mol. Genet. 10: 2907-2916 (2001). *
Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 2002. Hum. Immunol. 63: 1213-1268 (2002).
Marsh SG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Geraghty DE, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 2002. Tissue Antigens 60: 407-464 (2002). *
Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, MacH B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 2000. Eur. J. Immunogenet. 28: 377-424 (2001).
Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 2000. Tissue Antigens 57: 236-283 (2001). *
Marsh SG, Bodmer JG, Albert ED, Bodmer WF, Bontrop RE, Dupont B, Erlich HA, Hansen JA, Mach B, Mayr WR, Parham P, Petersdorf EW, Sasazuki T, Schreuder GM, Strominger JL, Svejgaard A, Terasaki PI. Nomenclature for factors of the HLA system, 2000. Hum. Immunol. 62: 419-468 (2001).
Marshall B, Leelayuwat C, Abraham LJ, Pinelli M, Dawkins RL. Large transcripts and sequence from a polymorphic 170 kb MHC region implicated in susceptibility to autoimmune disease. Immunogenetics 39: 15-20 (1994).
Marshall B, Leelayuwat C, Degli-Esposti MA, Pinelli M, Abraham LJ, Dawkins RL. New major histocompatibility complex genes. Hum. Immunol. 38: 24-29 (1993).
Marshall FA, Pearce EJ. Uncoupling of induced protein processing from maturation in dendritic cells exposed to a highly antigenic preparation from a helminth parasite. J. Immunol. 181: 7562-7570 (2008). *
Martel P, Gilbert D, Busson M, Loiseau P, Lepage V, Drouot L, Delaporte E, Prost C, Joly P, Charron D, Tron F. Epistasis between DSG1 and HLA class II genes in pemphigus foliaceus. Genes Immun. 3: 205-210 (2002). *
Martin AM, Nolan D, Gaudieri S, Almeida CA, Nolan R, James I, Carvalho F, Phillips E, Christiansen FT, Purcell AW, McCluskey J, Mallal S. Predisposition to abacavir hypersensitivity conferred by HLA-B*5701 and a haplotypic Hsp70-Hom variant. Proc. Natl. Acad. Sci. U.S.A. 101: 4180-4185 (2004). *
Martin TM, Zhang G, Luo J, Jin L, Doyle TM, Rajska BM, Coffman JE, Smith JR, Becker MD, Mackensen F, Khan MA, Levinson RD, Schumacher HR, Wade NK, Rosenbaum JT, Reveille JD. A locus on chromosome 9p predisposes to a specific disease manifestation, acute anterior uveitis, in ankylosing spondylitis, a genetically complex, multisystem, inflammatory disease. Arthritis Rheum. 52: 269-274 (2005). *
Martin-Pagola A, Perez-Nanclares G, Ortiz L, Vitoria JC, Hualde I, Zaballa R, Preciado E, Castano L, Bilbao JR. MICA response to gliadin in intestinal mucosa from celiac patients. Immunogenetics 56: 549-554 (2004). *
Martinelli Natzke A, Shaw JL, McKeller MR, Lambert Emo K, Mullen CA. Hematopoietic stem cell recipients do not develop post-transplantation immune tolerance to antigens present on minimal residual disease. Biol. Blood Marrow Transplant. 13: 34-45 (2007).
Martinez A, Alvarez-Lafuente R, Mas A, Bartolome M, Garcia-Montojo M, de Las Heras V, de la Concha EG, Arroyo R, Urcelay E. Environment-gene interaction in multiple sclerosis: human herpesvirus 6 and MHC2TA. Hum. Immunol. 68: 685-689 (2007).
Martinez A, Fernandez-Arquero M, Balsa A, Rubio A, Alves H, Pascual-Salcedo D, Martin-Mola E, de la Concha EG. Primary association of a MICA allele with protection against rheumatoid arthritis. Arthritis Rheum. 44: 1261-1265 (2001). *
Martinez A, Gual L, Fernandez-Arquero M, Nogales A, Ferreira A, Garcia-Rodriguez MC, Fontan G, de la Concha Ed EG. Epistatic effects occurring among susceptibility and protective MHC genes in IgA deficiency. Genes Immun. 4: 316-320 (2003). *
Martinez A, Nunez C, Martin MC, Mendoza JL, Taxonera C, Diaz-Rubio M, de la Concha EG, Urcelay E. Epistatic interaction between FCRL3 and MHC in Spanish patients with IBD. Tissue Antigens 69: 313-317 (2007). *
Martinez A, Perdigones N, Cenit MC, Espino L, Varade J, Lamas JR, Santiago JL, Fernandez-Arquero M, de la Calle H, Arroyo R, de la Concha EG, Fernandez-Gutierrez B, Urcelay E. Chromosomal region 16p13: further evidence of increased predisposition to immune diseases. Ann. Rheum. Dis. 69: 309-311 (2010).
Martinez A, Salido M, Bonilla G, Pascual-Salcedo D, Fernandez-Arquero M, De Miguel S, Balsa A, De La Concha EG, Fernandez-Gutierrez B. Association of the major histocompatibility complex with response to infliximab therapy in rheumatoid arthritis patients. Arthritis Rheum. 50: 1077-1082 (2004). *
Martinez A, Sanchez M, Varade J, Mas A, Martin MC, de Las Heras V, Arroyo R, Mendoza JL, Diaz-Rubio M, Fernandez-Gutierrez B, de la Concha EG, Urcelay E. Role of the MHC2TA gene in autoimmune diseases. Ann. Rheum. Dis. 66: 325-329 (2007). *
Martinez D, Vermeulen M, von Euw E, Sabatte J, Maggini J, Ceballos A, Trevani A, Nahmod K, Salamone G, Barrio M, Giordano M, Amigorena S, Geffner J. Extracellular acidosis triggers the maturation of human dendritic cells and the production of IL-12. J. Immunol. 179: 1950-1959 (2007). *
Martinez M, Samms M, Hendrix TM, Adeosun O, Pezzano M, Guyden JC. Thymic nurse cell multicellular complexes in HY-TCR transgenic mice demonstrate their association with MHC restriction. Exp. Biol. Med. (Maywood) 232: 780-788 (2007). *
Martinez-Borra J, Brautbar C, Gonzalez S, Enk CD, Lopez-Vazquez A, Lopez-Larrea C. The region of 150 kb telometic to HLA-C is associated with psoriasis in the Jewish population. J. Invest. Dermatol. 125: 928-932 (2005). *
Martinez-Borra J, Khakoo SI. Speed and selection in the evolution of killer-cell immunoglobulin-like receptors. Int. J. Immunogenet. 35: 89-96 (2008). *
Martinez-Mir A, Zlotogorski A, Gordon D, Petukhova L, Mo J, Gilliam TC, Londono D, Haynes C, Ott J, Hordinsky M, Nanova K, Norris D, Price V, Duvic M, Christiano AM. Genomewide scan for linkage reveals evidence of several susceptibility loci for alopecia areata. Am. J. Hum. Genet. 80: 316-328 (2007). *
Martins VC, Boehm T, Bleul CC. Ltbetar signaling does not regulate Aire-dependent transcripts in medullary thymic epithelial cells. J. Immunol. 181: 400-407 (2008). *
Maruyama K, Sano G, Matsuo K. Murine osteoblasts respond to LPS and IFN-gamma similarly to macrophages. J. Bone Miner. Metab. 24: 454-460 (2006). *
Marx N, Kehrle B, Kohlhammer K, Grub M, Koenig W, Hombach V, Libby P, Plutzky J. PPAR activators as antiinflammatory mediators in human T lymphocytes: implications for atherosclerosis and transplantation-associated arteriosclerosis. Circ. Res. 90: 703-710 (2002). *
Mascolo D, Barba P, De Berardinis P, Di Rosa F, Del Pozzo G. Phage display of a CTL epitope elicits a long-term in vivo cytotoxic response. FEMS Immunol. Med. Microbiol. 50: 59-66 (2007). *
Mastaglia F, Price P, Walters S, Fabian V, Miller J, Zilko P. Familial inclusion body myositis in a mother and son with different ancestral MHC haplotypes. Neuromuscul. Disord. 16: 754-758 (2006).
Mastaglia FL. Sporadic inclusion body myositis: variability in prevalence and phenotype and influence of the MHC. Acta Myol. 28: 66-71 (2009).
Mastaglia FL, Needham M, Scott A, James I, Zilko P, Day T, Kiers L, Corbett A, Witt CS, Allcock R, Laing N, Garlepp M, Christiansen FT. Sporadic inclusion body myositis: HLA-DRB1 allele interactions influence disease risk and clinical phenotype. Neuromuscul. Disord. 19: 763-765 (2009).
Mastroeni P, Menager N. Development of acquired immunity to Salmonella. J. Med. Microbiol. 52: 453-459 (2003). *
Masuda A, Nakamura A, Maeda T, Sakamoto Y, Takai T. Cis binding between inhibitory receptors and MHC class I can regulate mast cell activation. J. Exp. Med. 204: 907-920 (2007). *
Matejuk A, Afentoulis M. Association of CD45(dim)VLA-4 (+) cells with the NKT cell lineage and their selective expression of IL-13, IP-15, and CCR3 transcripts. Arch. Immunol. Ther. Exp. (Warsz.) 54: 183-191 (2006).
Matri S, Boubaker J, Hamzaoui S, Bardi R, Ayed K, Filali A. The role of major histocompatibility complex genes in the pathogenesis of chronic inflammatory bowel diseases. Tunis. Med. 81: 289-294 (2003).
Matsumoto T, Kitano A, Nakamura S, Oshitani N, Obata A, Hashimura H, Hiki M, Okawa K, Nagura H, Kobayashi K. Immunocytochemical characterization of the DNA-polymerase alpha-positive colonic mucosal epithelial cells in patients with ulcerative colitis. Nippon Shokakibyo Gakkai Zasshi 86: 1611-1616 (1989).
Matsumura S, Kita H, He XS, Ansari AA, Lian ZX, Van De Water J, Yamamoto K, Tsuji T, Coppel RL, Kaplan M, Gershwin ME. Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosis. Hepatology 36: 1125-1134 (2002). *
Matsumura Y, Kobayashi T, Ichiyama K, Yoshida R, Hashimoto M, Takimoto T, Tanaka K, Chinen T, Shichita T, Wyss-Coray T, Sato K, Yoshimura A. Selective expansion of Foxp3-positive regulatory T cells and immunosuppression by suppressors of cytokine signaling 3-deficient dendritic cells. J. Immunol. 179: 2170-2179 (2007). *
Matsunaga Y, Fukuma D, Hirata S, Fukushima S, Haruta M, Ikeda T, Negishi I, Nishimura Y, Senju S. Activation of antigen-specific cytotoxic T lymphocytes by beta2-microglobulin or TAP1 gene disruption and the introduction of recipient-matched MHC class I gene in allogeneic embryonic stem cell-derived dendritic cells. J. Immunol. 181: 6635-6643 (2008). *
Matsuzaka Y, Makino S, Nakajima K, Tomizawa M, Oka A, Bahram S, Kulski JK, Tamiya G, Inoko H. New polymorphic microsatellite markers in the human MHC class III region. Tissue Antigens 57: 397-404 (2001). *
Matsuzaka Y, Makino S, Nakajima K, Tomizawa M, Oka A, Kimura M, Bahram S, Tamiya G, Inoko H. New polymorphic microsatellite markers in the human MHC class II region. Tissue Antigens 56: 492-500 (2000). *
Matsuzaki J, Qian F, Luescher I, Lele S, Ritter G, Shrikant PA, Gnjatic S, Old LJ, Odunsi K. Recognition of naturally processed and ovarian cancer reactive CD8+ T cell epitopes within a promiscuous HLA class II T-helper region of NY-ESO-1. Cancer Immunol. Immunother. 57: 1185-1195 (2008). *
Mattapallil MJ, Augello A, Cheadle C, Teichberg D, Becker K, Chan CC, Mattapallil JJ, Pennesi G, Caspi RR. Differentially expressed genes in MHC-compatible rat strains that are susceptible or resistant to experimental autoimmune uveitis. Invest. Ophthalmol. Vis. Sci. 49: 1957-1970 (2008). *
Mattapallil MJ, Sahin A, Silver PB, Sun SH, Chan CC, Remmers EF, Hejtmancik JF, Caspi RR. Common genetic determinants of uveitis shared with other autoimmune disorders. J. Immunol. 180: 6751-6759 (2008). *
Matthews SP, Werber I, Deussing J, Peters C, Reinheckel T, Watts C. Distinct protease requirements for antigen presentation in vitro and in vivo. J. Immunol. 184: 2423-2431 (2010).
Matthews VB, Witt CS, French MA, Machulla HK, De la Concha EG, Cheong KY, Vigil P, Hollingsworth PN, Warr KJ, Christiansen FT, Price P. Central MHC genes affect IgA levels in the human: reciprocal effects in IgA deficiency and IgA nephropathy. Hum. Immunol. 63: 424-433 (2002).
Matzner N, Zemtsova IM, Nguyen TX, Duszenko M, Shumilina E, Lang F. Ion channels modulating mouse dendritic cell functions. J. Immunol. 181: 6803-6809 (2008). *
Maverakis E, Beech JT, Schneider S, Sercarz EE. Presentation of a determinant by MHC class II can be prevented through competitive capture by a flanking determinant on a multideterminant peptide. J. Autoimmun. 31: 59-65 (2008).
Mayer F, Brunner A. Non-neutral evolution of the major histocompatibility complex class II gene DRB1 in the sac-winged bat Saccopteryx bilineata. Heredity 99: 257-264 (2007). *
Mayer L. Epithelial cell antigen presentation. Curr. Opin. Gastroenterol. 16: 531-535 (2000).
Mayo S, Quinn A. Altered susceptibility to EAE in congenic NOD mice: altered processing of the encephalitogenic MOG35-55 peptide by NOR/LtJ mice. Clin. Immunol. 122: 91-100 (2007). *
Mayuzumi N, Matsushima H, Takashima A. IL-33 promotes DC development in BM culture by triggering GM-CSF production. Eur. J. Immunol. 39: 3331-3342 (2009). *
Mazza C, Auphan-Anezin N, Gregoire C, Guimezanes A, Kellenberger C, Roussel A, Kearney A, van der Merwe PA, Schmitt-Verhulst AM, Malissen B. How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides? EMBO J. 26: 1972-1983 (2007). *
Mc Quillan KL, Lynch MA, Mills KH. Activation of mixed glia by Abeta-specific Th1 and Th17 cells and its regulation by Th2 cells. Brain Behav. Immun. Jan 7 [Epub ahead of print] (2010).
McAdam SN, Fleckenstein B, Rasmussen IB, Schmid DG, Sandlie I, Bogen B, Viner NJ, Sollid LM. T cell recognition of the dominant I-A(k)-restricted hen egg lysozyme epitope: critical role for asparagine deamidation. J. Exp. Med. 193: 1239-1246 (2001). *
McArdle S. Cancer vaccines: uses of HLA transgenic mice compared to genetically modified mice. Front. Biosci. 14: 4640-4651 (2009).
McBeth C, Seamons A, Pizarro JC, Fleishman SJ, Baker D, Kortemme T, Goverman JM, Strong RK. A new twist in TCR diversity revealed by a forbidden alphabeta TCR. J. Mol. Biol. 375: 1306-1319 (2008). *
McCann FE, Eissmann P, Onfelt B, Leung R, Davis DM. The activating NKG2D ligand MHC class I-related chain A transfers from target cells to NK cells in a manner that allows functional consequences. J. Immunol. 178: 3418-3426 (2007). *
McCarey DW, Sattar N, McInnes IB. Do the pleiotropic effects of statins in the vasculature predict a role in inflammatory diseases? Arthritis Res. Ther. 7: 55-61 (2005). *
McCauley JL, Zuvich RL, Bradford Y, Kenealy SJ, Schnetz-Boutaud N, Gregory SG, Hauser SL, Oksenberg JR, Mortlock DP, Pericak-Vance MA, Haines JL. Follow-up examination of linkage and association to chromosome 1q43 in multiple sclerosis. Genes Immun. 10: 624-630 (2009).
McDevitt HO. The genetics of the HLA system. J. Rheumatol. Suppl. 10: 50-53 (1983).
McDevitt HO. Discovering the role of the major histocompatibility complex in the immune response. Annu. Rev. Immunol. 18: 1-17 (2000). *
McDonagh AJ, Tazi-Ahnini R. Epidemiology and genetics of alopecia areata. Clin. Exp. Dermatol. 27: 405-409 (2002). *
McElroy JP, Oksenberg JR. Multiple sclerosis genetics. Curr. Top. Microbiol. Immunol. 318: 45-72 (2008).
McGarry F, Walker R, Sturrock R, Field M. The -308.1 polymorphism in the promoter region of the tumor necrosis factor gene is associated with ankylosing spondylitis independent of HLA-B27. J. Rheumatol. 26: 1110-1116 (1999).
McGehee AM, Dougan SK, Klemm EJ, Shui G, Park B, Kim YM, Watson N, Wenk MR, Ploegh HL, Hu CC. XBP-1-deficient plasmablasts show normal protein folding but altered glycosylation and lipid synthesis. J. Immunol. 183: 3690-3699 (2009).
McGinnis R, McLaren W, Ranganath V, Whittaker P, Hunt S, Deloukas P; Diabetes Genetics Consortium. Haplotype-based search for SNPs associated with differential type 1 diabetes risk among chromosomes carrying a specific HLA DRB1-DQA1-DQB1 haplotype. Diabetes Obes. Metab. 11 Suppl. 1: 8-16 (2009). *
McGonagle D, Savic S, McDermott MF. The NLR network and the immunological disease continuum of adaptive and innate immune-mediated inflammation against self. Semin. Immunopathol. 29: 303-313 (2007). *
McGuire HM, Vogelzang A, Hill N, Flodstrom-Tullberg M, Sprent J, King C. Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus. Proc. Natl. Acad. Sci. U.S.A. 106: 19438-19443 (2009). *
McHeyzer-Williams LJ, McHeyzer-Williams MG. Antigen-specific memory B cell development. Annu. Rev. Immunol. 23: 487-513 (2005). *
McHugh NJ, Owen P, Cox B, Dunphy J, Welsh K. MHC class II, tumour necrosis factor alpha, and lymphotoxin alpha gene haplotype associations with serological subsets of systemic lupus erythematosus. Ann. Rheum. Dis. 65: 488-494 (2006). *
McKay D, Shigeoka A, Rubinstein M, Surh C, Sprent J. Simultaneous deletion of MyD88 and Trif delays major histocompatibility and minor antigen mismatch allograft rejection. Eur. J. Immunol. 36: 1994-2002 (2006). *
McKinnon E, Morahan G, Nolan D, James I; Diabetes Genetics Consortium. Association of MHC SNP genotype with susceptibility to type 1 diabetes: a modified survival approach. Diabetes Obes. Metab. 11 Suppl. 1: 92-100 (2009). *
McLachlan JB, Catron DM, Moon JJ, Jenkins MK. Dendritic cell antigen presentation drives simultaneous cytokine production by effector and regulatory T cells in inflamed skin. Immunity 30: 277-288 (2009). *
McLachlan SM, Aliesky HA, Pichurin PN, Chen CR, Williams RW, Rapoport B. Shared and unique susceptibility genes in a mouse model of Graves' disease determined in BXH and CXB recombinant inbred mice. Endocrinology 149: 2001-2009 (2008). *
McManus R, Moloney M, Borton M, Finch A, Chuan YT, Lawlor E, Weir DG, Kelleher D. Association of celiac disease with microsatellite polymorphisms close to the tumor necrosis factor genes. Hum. Immunol. 45: 24-31 (1996).
McManus R, Wilson AG, Mansfield J, Weir DG, Duff GW, Kelleher D. TNF2, a polymorphism of the tumour necrosis-alpha gene promoter, is a component of the celiac disease major histocompatibility complex haplotype. Eur. J. Immunol. 26: 2113-2118 (1996).
McPherson M, Wei B, Turovskaya O, Fujiwara D, Brewer S, Braun J. Colitis immunoregulation by CD8+ T cell requires T cell cytotoxicity and B cell peptide antigen presentation. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G485-G492 (2008). *
McQueen KL, Parham P. Variable receptors controlling activation and inhibition of NK cells. Curr. Opin. Immunol. 14: 615-621 (2002).
McTernan CL, Stewart LC, Mijovic CH, Barnett AH. Assessment of the non-HLA-DR-DQ contribution to IDDM1 in British Caucasian families: analysis of LMP7 polymorphisms. Diabet. Med. 17: 661-666 (2000). *
McWilliams JA, Sanchez PJ, Haluszczak C, Gapin L, Kedl RM. Multiple innate signaling pathways cooperate with CD40 to induce potent, CD70-dependent cellular immunity. Vaccine Dec 5 [Epub ahead of print] (2009). *
Medina F, Ramos M, Iborra S, de Leon P, Rodriguez-Castro M, Del Val M. Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo. J. Immunol. 183: 4639-4647 (2009).
Medlej-Hashim M, Loiselet J, Lefranc G, Megarbane A. Familial Mediterranean Fever (FMF): from diagnosis to treatment. Sante 14: 261-266 (2004).
Mee JB, Johnson CM, Morar N, Burslem F, Groves RW. The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis. Am. J. Pathol. 171: 32-42 (2007). *
Meemboor S, Mertens J, Flenner E, Groneck L, Zingarelli A, Gamstatter T, Bessler M, Seeger JM, Kashkar H, Odenthal M, Kalka-Moll WM. Interleukin-6 is essential for zwitterionic polysaccharide-mediated abscess formation. Innate Immun. Nov 6 [Epub ahead of print] (2009).
Meguro A, Inoko H, Ota M, Katsuyama Y, Oka A, Okada E, Yamakawa R, Yuasa T, Fujioka T, Ohno S, Bahram S, Mizuki N. Genetics of Behcet's disease inside and outside the MHC. Ann. Rheum. Dis. Aug 13 [Epub ahead of print] (2009).
Mehling M, Simon P, Mittelbronn M, Meyermann R, Ferrone S, Weller M, Wiendl H. WHO grade associated downregulation of MHC class I antigen-processing machinery components in human astrocytomas: does it reflect a potential immune escape mechanism? Acta Neuropathol. (Berl.) 114: 111-119 (2007).
Mehra NK, Kaur G. MHC-based vaccination approaches: progress and perspectives. Expert Rev. Mol. Med. 5: 1-17 (2003).
Mehra NK, Kaur G. 14th International HLA and Immunogenetics Workshop: report on joint study on MHC and infection. Tissue Antigens 69 Suppl. 1: 226-227 (2007). *
Mehra NK, Kaur G, Jaini R. Genetic diversity in the human major histocompatibility complex: lessons for vaccination approaches to HIV infection. Community Genet. 5: 162-166 (2002).
Mehra NK, Kumar N, Kaur G, Kanga U, Tandon N. Biomarkers of susceptibility to type 1 diabetes with special reference to the Indian population. Indian J. Med. Res. 125: 321-344 (2007). *
Mein CA, Esposito L, Dunn MG, Johnson GC, Timms AE, Goy JV, Smith AN, Sebag-Montefiore L, Merriman ME, Wilson AJ, Pritchard LE, Cucca F, Barnett AH, Bain SC, Todd JA. A search for type 1 diabetes susceptibility genes in families from the United Kingdom. Nat. Genet. 19: 297-300 (1998). *
Mekala DJ, Alli RS, Geiger TL. IL-10-dependent suppression of experimental allergic encephalomyelitis by Th2-differentiated, anti-TCR redirected T lymphocytes. J. Immunol. 174: 3789-3797 (2005). *
Mekala DJ, Geiger TL. Immunotherapy of autoimmune encephalomyelitis with re-directed CD4+CD25+ T-lymphocytes. Blood 105: 2090-2092 (2005). *
Melendez Hernandez JD, Jimenez-Huyke C, Rosado K, Gonzalez-Keelan C, Lojo JJ, Torres EA. Surveillance for dysplasia in patients with ileal pouch-anal anastomosis for ulcerative colitis: an interim analysis. Dig. Dis. Sci. Oct 20 [Epub ahead of print] (2009). *
Melkus MW, Estes JD, Padgett-Thomas A, Gatlin J, Denton PW, Othieno FA, Wege AK, Haase AT, Garcia JV. Humanized mice mount specific adaptive and innate immune responses to EBV and TSST-1. Nat. Med. 12: 1316-1322 (2006). *
Mella JG, Roschmann E, Maier KP, Volk BA. Association of primary biliary cirrhosis with the allele HLA-DPB1*0301 in a German population. Hepatology 21: 398-402 (1995).
Melo N, Morais A, Alves H, Lima B, Tafulo S, Goncalves R. HLA - A, -C, -B, -DRB1 e -DQB polymorphisms in extrinsic allergic alveolitis (EAA). Rev. Port. Pneumol. 11: S29 (2005).
Melum E, Karlsen TH, Schrumpf E, Bergquist A, Thorsby E, Boberg KM, Lie BA. Cholangiocarcinoma in primary sclerosing cholangitis is associated with NKG2D polymorphisms. Hepatology 47: 90-96 (2008). *
Menard LC, Minns LA, Darche S, Mielcarz DW, Foureau DM, Roos D, Dzierszinski F, Kasper LH, Buzoni-Gatel D. B cells amplify IFN-gamma production by T cells via a TNF-alpha-mediated mechanism. J. Immunol. 179: 4857-4866 (2007). *
Menconi F, Monti MC, Greenberg DA, Oashi T, Osman R, Davies TF, Ban Y, Jacobson EM, Concepcion ES, Wun Li C, Tomer Y. Molecular amino acid signatures in the MHC class II peptide-binding pocket predispose to autoimmune thyroiditis in humans and in mice. Proc. Natl. Acad. Sci. U.S.A. 105: 14034-14039 (2008). *
Menier C, Rouas-Freiss N, Favier B, Lemaoult J, Moreau P, Carosella ED. Recent advances on the non-classical major histocompatibility complex class I HLA-G molecule. Tissue Antigens. Dec 30 [Epub ahead of print] (2009). *
Mennechet FJ, Uze G. Interferon {lambda}-treated dendritic cells specifically induce proliferation of FOXP3-expressing suppressor T cells. Blood 107: 4417-4423 (2006). *
Mercer JC, Ragin MJ, August A. Natural killer T cells: rapid responders controlling immunity and disease. Int. J. Biochem. Cell. Biol. 37: 1337-1343 (2005). *
Merino R, Iwamoto M, Gershwin ME, Izui S. The Yaa gene abrogates the major histocompatibility complex association of murine lupus in (NZB x BXSB)F1 hybrid mice. J. Clin. Invest. 94: 521-525 (1994). *
Merriman TR, Cordell HJ, Eaves IA, Danoy PA, Coraddu F, Barber R, Cucca F, Broadley S, Sawcer S, Compston A, Wordsworth P, Shatford J, Laval S, Jirholt J, Holmdahl R, Theofilopoulos AN, Kono DH, Tuomilehto J, et al. Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases. Diabetes 50: 184-194 (2001). *
Messmer D, Yang H, Telusma G, Knoll F, Li J, Messmer B, Tracey KJ, Chiorazzi N. High mobility group box protein 1: an endogenous signal for dendritic cell maturation and Th1 polarization. J. Immunol. 173: 307-313 (2004). *
Meth MJ, Sperber KE. Phenotypic diversity in delayed drug hypersensitivity: an immunologic explanation. Mt. Sinai J. Med. 73: 769-776 (2006). *
Methe H, Edelman ER. Tissue engineering of endothelial cells and the immune response. Transplant. Proc. 38: 3293-3299 (2006). *
Metwali A, Setiawan T, Blum AM, Urban J, Elliott DE, Hang L, Weinstock JV. Induction of CD8+ regulatory T cells in the intestine by Heligmosomoides polygyrus infection. Am. J. Physiol. Gastrointest. Liver Physiol. 291: G253-G259 (2006). *
Meunier L, Bohjanen K, Voorhees JJ, Cooper KD. Retinoic acid upregulates human Langerhans cell antigen presentation and surface expression of HLA-DR and CD11c, a beta 2 integrin critically involved in T-cell activation. J. Invest. Dermatol. 103: 775-779 (1994). *
Mewar D, Marinou I, Lee ME, Timms JM, Kilding R, Teare MD, Read RC, Wilson AG. Haplotype-specific gene expression profiles in a telomeric major histocompatibility complex gene cluster and susceptibility to autoimmune diseases. Genes Immun. 7: 625-631 (2006). *
Mia MY, Kim EY, Satpute SR, Moudgil KD. The dynamics of articular leukocyte trafficking and the immune response to self heat-shock protein 65 influence arthritis susceptibility. J. Clin. Immunol. 28: 420-431 (2008). *
Miceli-Richard C, Comets E, Loiseau P, Puechal X, Hachulla E, Mariette X. Association of an IRF5 gene functional polymorphism with Sjogren's syndrome. Arthritis Rheum. 56: 3989-3994 (2007). *
Michaels MA, Kang HK, Kaliyaperumal A, Satyaraj E, Shi Y, Datta SK. A defect in deletion of nucleosome-specific autoimmune T cells in lupus-prone thymus: role of thymic dendritic cells. J. Immunol. 175: 5857-5865 (2005). *
Middendorp S, Nieuwenhuis EE. NKT cells in mucosal immunity. Mucosal Immunol. 2: 393-402 (2009).
Middleton PG. Non-HLA gene polymorphisms in stem cell transplantation. Methods Mol. Med. 134: 97-114 (2007).
Mifsud NA, Purcell AW, Chen W, Holdsworth R, Tait BD, McCluskey J. Immunodominance hierarchies and gender bias in direct T(CD8)-cell alloreactivity. Am. J. Transplant. 8: 121-132 (2008).
Miglio F, Pignatelli M, Mazzeo V, Baraldini M, Stefanini GF, Guardigli G, Bandini G, Ricci P, Tura S, Gasbarrini G. Expression of major histocompatibility complex class II antigens on bile duct epithelium in patients with hepatic graft-versus-host disease after bone marrow transplantation. J. Hepatol. 5: 182-189 (1987).
Mijovic CH, Barnett AH, Todd JA. Genetics of diabetes. Trans-racial gene mapping studies. Baillieres Clin. Endocrinol. Metab. 5: 321-340 (1991).
Miki T, Strom SC. Amnion-derived pluripotent/multipotent stem cells. Stem Cell Rev. 2: 133-142 (2006).
Milicic A, Lindheimer F, Laval S, Rudwaleit M, Ackerman H, Wordsworth P, Hohler T, Brown MA. Interethnic studies of TNF polymorphisms confirm the likely presence of a second MHC susceptibility locus in ankylosing spondylitis. Genes Immun. 1: 418-422 (2000). *
Millo E, Damonte G. HPLC and MS analysis for the identification and characterisation of peptides presented in the context of the non-classical human leukocytes antigen (HLA) class I molecule HLA-E. Curr. Pharm. Des. 15: 3325-3335 (2009).
Milosevic S, Behrends U, Adhikary D, Mautner J. Identification of major histocompatibility complex class II-restricted antigens and epitopes of the Epstein-Barr virus by a novel bacterial expression cloning approach. J. Virol. 80: 10357-10364 (2006). *
Mircheff AK. Sjogrens syndrome as failed local immunohomeostasis: prospects for cell-based therapy. Ocul. Surf. 1: 160-179 (2003).
Miretti MM, Beck S. Immunogenomics: molecular hide and seek. Hum. Genomics 2: 244-251 (2006).
Miretti MM, Walsh EC, Ke X, Delgado M, Griffiths M, Hunt S, Morrison J, Whittaker P, Lander ES, Cardon LR, Bentley DR, Rioux JD, Beck S, Deloukas P. A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms. Am. J. Hum. Genet. 76: 634-646 (2005). *
Misharin AV, Rapoport B, McLachlan SM. Thyroid antigens, not central tolerance, control responses to immmunization in BALB/C versus C57BL/6 mice. Thyroid 19: 503-509 (2009).
Mishto M, Bellavista E, Ligorio C, Textoris-Taube K, Santoro A, Giordano M, D'Alfonso S, List� F, Nacmias B, Cellini E, Leone M, Grimaldi LM, Fenoglio C, Esposito F, Martinelli-Boneschi F, Galimberti D, Scarpini E, Seifert U, Amato MP, Caruso C, et al. Immunoproteasome LMP2 60HH variant alters MBP epitope generation and reduces the risk to develop multiple sclerosis in Italian female population. PLoS One 5: e9287 (2010).
Mistry AR, O'Callaghan CA. Regulation of ligands for the activating receptor NKG2D. Immunology 121: 439-447 (2007). *
Mitchison NA, Mayer W. A survey of H2 gene sequences, including new wild-derived genes. Int. J. Immunogenet. 34: 3-12 (2007). *
Mitchison NA, Ono SJ, Stephens HA. Does the polymorphism of MHC class II promoters matter? Cell. Immunol. 233: 162-165 (2005). *
Mitra-Kaushik S, Cruz J, Stern LJ, Ennis FA, Terajima M. Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses. J. Immunol. 179: 1303-1312 (2007). *
Mittal KK. Immunobiology of the human major histocompatibility complex: association of HLA antigens with disease. Acta Anthropogenet. 8: 245-268 (1984).
Mix E, Pahnke J, Ibrahim SM. Gene-expression profiling of experimental autoimmune encephalomyelitis. Neurochem. Res. 27: 1157-1163 (2002). *
Miyagawa S, Amagai M, Niizeki H, Yamashina Y, Kaneshige T, Nishikawa T, Shirai T, Inoko H. HLA-DRB1 polymorphisms and autoimmune responses to desmogleins in Japanese patients with pemphigus. Tissue Antigens 54: 333-340 (1999).
Miyagawa S, Shinohara K, Kidoguchi K, Fujita T, Fukumoto T, Hashimoto K, Yoshioka A, Shirai T. Neonatal lupus erythematosus: studies on HLA class II genes and autoantibody profiles in Japanese mothers. Autoimmunity 26: 95-101 (1997).
Miyake S. iNKT cells, a friend or a foe for autoimmune disease and allergy? Nihon Rinsho Meneki Gakkai Kaishi 29: 27-36 (2006). *
Miyake S, Yamamura T. Therapeutic potential of glycolipid ligands for natural killer (NK) T cells in the suppression of autoimmune diseases. Curr. Drug Targets Immune Endocr. Metabol. Disord. 5: 315-322 (2005).
Miyake S, Yamamura T. NKT cells and autoimmune diseases: unraveling the complexity. Curr. Top. Microbiol. Immunol. 314: 251-267 (2007).
Miyake Y, Yamamoto K. Current status of autoimmune hepatitis in Japan. Acta Med. Okayama 62: 217-226 (2008). *
Miyazaki T, Doy M, Unno R, Honda A, Ikegami T, Itoh S, Bouscarel B, Matsuzaki Y. Regulatory T cells and liver pathology in a murine graft versus host response model. Hepatol. Res. 39: 585-594 (2009).
Mizuki N, Inoko H, Ohno S. Molecular genetics (HLA) of Behcet's disease. Yonsei Med. J. 38: 333-349 (1997). *
Mizuki N, Meguro A, Tohnai I, Gul A, Ohno S, Mizuki N. Association of major histocompatibility complex class I chain-related gene A and HLA-B alleles with Behcet's disease in Turkey. Jpn. J. Ophthalmol. 51: 431-4361 (2007).
Mizuki N, Ota M, Katsuyama Y, Yabuki K, Ando H, Goto K, Nakamura S, Bahram S, Ohno S, Inoko H. Association analysis between the MIC-A and HLA-B alleles in Japanese patients with Behcet's disease. Arthritis Rheum. 42: 1961-1966 (1999). *
Mizuki N, Ota M, Kimura M, Ohno S, Ando H, Katsuyama Y, Yamazaki M, Watanabe K, Goto K, Nakamura S, Bahram S, Inoko H. Triplet repeat polymorphism in the transmembrane region of the MICA gene: a strong association of six GCT repetitions with Behcet disease. Proc. Natl. Acad. Sci. U.S.A. 94: 1298-1303 (1997). *
Mizukoshi E, Nakamoto Y, Marukawa Y, Arai K, Yamashita T, Tsuji H, Kuzushima K, Takiguchi M, Kaneko S. Cytotoxic T cell responses to human telomerase reverse transcriptase in patients with hepatocellular carcinoma. Hepatology 43: 1284-1294 (2006). *
Mizutori Y, Nagayama Y, Flower D, Misharin A, Aliesky HA, Rapoport B, McLachlan SM. Role of the transgenic human thyrotropin receptor A-subunit in thyroiditis induced by A-subunit immunization and regulatory T cell depletion. Clin. Exp. Immunol. 154: 305-315 (2008). *
Mizutori Y, Saitoh O, Eguchi K, Nagayama Y. Lack of effect of methimazole on dendritic cell (DC) function and DC-induced Graves' hyperthyroidism in mice. Autoimmunity 40: 397-402 (2007).
Moalem-Taylor G, Allbutt HN, Iordanova MD, Tracey DJ. Pain hypersensitivity in rats with experimental autoimmune neuritis, an animal model of human inflammatory demyelinating neuropathy. Brain Behav. Immun. 21: 699-710 (2007).
Moesta AK, Abi-Rached L, Norman PJ, Parham P. Chimpanzees use more varied receptors and ligands than humans for inhibitory killer cell Ig-like receptor recognition of the MHC-C1 and MHC-C2 epitopes. J. Immunol. 182: 3628-3637 (2009).
Moffatt MF, Schou C, Faux JA, Abecasis GR, James A, Musk AW, Cookson WO. Association between quantitative traits underlying asthma and the HLA-DRB1 locus in a family-based population sample. Eur. J. Hum. Genet. 9: 341-346 (2001). *
Moffett-King A. Natural killer cells and pregnancy. Nat. Rev. Immunol. 2: 656-663 (2002). *
Mohammadi J, Pourpak Z, Jarefors S, Saghafi S, Zendehdel K, Pourfathollah AA, Amirzargar AA, Aghamohammadi A, Moin M, Hammarstrom L. Human leukocyte antigens (HLA) associated with selective IgA deficiency in Iran and Sweden. Iran J. Allergy Asthma Immunol. 7: 209-214 (2008).
Mohammadi J, Ramanujam R, Jarefors S, Rezaei N, Aghamohammadi A, Gregersen PK, Hammarstrom L. IgA deficiency and the MHC: assessment of relative risk and microheterogeneity within the HLA A1 B8, DR3 (8.1) haplotype. J. Clin. Immunol. Oct 16 [Epub ahead of print] (2009). *
Mohammed F, Cobbold M, Zarling AL, Salim M, Barrett-Wilt GA, Shabanowitz J, Hunt DF, Engelhard VH, Willcox BE. Phosphorylation-dependent interaction between antigenic peptides and MHC class I: a molecular basis for the presentation of transformed self. Nat. Immunol. 9: 1236-1243 (2008). *
Mohammed K, Pope J, le Riche N, Brintnell W, Cairns E, Coles R, Bell DA. Association of severe inflammatory polyarthritis in primary Sjogren's syndrome: clinical, serologic, and HLA analysis. J. Rheumatol. 36: 1937-1942 (2009).
Mohebbi N, Wagner CA. The "antibodyome": or, how to find antibodies? J. Nephrol. 22: 439-441 (2009).
Moisini I, Nguyen P, Fugger L, Geiger TL. Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. J. Immunol. 180: 3601-3611 (2008). *
Molinero LL, Fuertes MB, Girart MV, Fainboim L, Rabinovich GA, Costas MA, Zwirner NW. NF-kappa B regulates expression of the MHC class I-related chain A gene in activated T lymphocytes. J. Immunol. 173: 5583-5590 (2004). *
Moller B, Kerschbaumer G, Komor M, Kerschbaumer F, Ottmann OG, Hoelzer D, Hofmann WK. Genomic imprinting of insulin-like growth factor 2 (IGF-2) in chronic synovitis. Growth Horm. IGF Res. 17: 500-505 (2007).
Mombaerts P, Mizoguchi E, Grusby MJ, Glimcher LH, Bhan AK, Tonegawa S. Spontaneous development of inflammatory bowel disease in T cell receptor mutant mice. Cell 75: 274-282 (1993).
Momburg F, Koretz K, Von Herbay A, Moller P. Nonimmune human cells can express MHC class II antigens in the absence of invariant chain - an immunohistological study on normal and chronically inflamed small intestine. Clin. Exp. Immunol. 72: 367-372 (1988). *
Monaco JJ, Nandi D. The genetics of proteasomes and antigen processing. Annu. Rev. Genet. 29: 729-754 (1995). *
Mondal TK, Saha SK, Miller VM, Seegal RF, Lawrence DA. Autoantibody-mediated neuroinflammation: pathogenesis of neuropsychiatric systemic lupus erythematosus in the NZM88 murine model. Brain Behav. Immun. 22: 949-959 (2008).
Monsuur AJ, de Bakker PI, Zhernakova A, Pinto D, Verduijn W, Romanos J, Auricchio R, Lopez A, van Heel DA, Crusius JB, Wijmenga C. Effective detection of human leukocyte antigen risk alleles in celiac disease using tag single nucleotide polymorphisms. PLoS ONE 3: e2270 (2008). *
Montano-Loza AJ, Carpenter HA, Czaja AJ. Clinical significance of HLA DRB103-DRB104 in type 1 autoimmune hepatitis. Liver Int. 26: 1201-1208 (2006). *
Monteleone I, Platt AM, Jaensson E, Agace WW, Mowat AM. IL-10-dependent partial refractoriness to Toll-like receptor stimulation modulates gut mucosal dendritic cell function. Eur. J. Immunol. 38: 1533-1547 (2008). *
Montes-Cano MA, Caro-Oleas JL, Romero-Gomez M, Diago M, Andrade R, Carmona I, Reina JA, Nunez-Roldan A, Gonzalez-Escribano MF. HLA-C and KIR genes in hepatitis C virus infection. Hum. Immunol. 66: 1106-1109 (2005).
Moody DB, Porcelli SA. Intracellular pathways of CD1 antigen presentation. Nat. Rev. Immunol. 3: 11-22 (2003).
Mor F, Cohen IR. How special is a pathogenic CNS autoantigen? Immunization to many CNS self-antigens does not induce autoimmune disease. J. Neuroimmunol. 174: 3-11 (2006).
Morales-Buenrostro LE, Alberu J. Anti-major histocompatibility complex class I-related chain A antibodies in organ transplantation. Transplant. Rev. (Orlando) 22: 27-38 (2008).
Morar B, Schwab SG, Albus M, Maier W, Lerer B, Wildenauer DB. Evaluation of association of SNPs in the TNF alpha gene region with schizophrenia. Am. J. Med. Genet. B. Neuropsychiatr. Genet. 144: 318-324 (2007).
Mordes JP, Cort L, Norowski E, Leif J, Fuller JM, Lernmark A, Greiner DL, Blankenhorn EP. Analysis of the rat Iddm14 diabetes susceptibility locus in multiple rat strains: identification of a susceptibility haplotype in the Tcrb-V locus. Mamm. Genome 20: 162-169 (2009). *
Moreau AS, Sebti Y, Duhamel A, Roccaro AM, Coiteux V, Gastinne T, Le Friec G, Burwik N, Amiot L, Ho AW, Poulain S, Hennache B, Hunter ZR, Dessaint JP, Ghobrial IM, Treon SP, Facon T, Zorn E, Leleu X. Clinical relevance of soluble HLA class I molecules in Waldenstrom macroglobulinemia. Eur. J. Haematol. 80: 503-509 (2008). *
Morel E, Bellon T. Amoxicillin conjugates to HLA class I molecules and interferes with signalling through the ILT2/LIR-1/CD85j inhibitory receptor. Allergy 62: 190-196 (2007). *
Morel PA, Erlich HA, Fathman CG. A new look at the shared epitope hypothesis. Am. J. Med. 85: 20-22 (1988).
Morelli AE. The immune regulatory effect of apoptotic cells and exosomes on dendritic cells: its impact on transplantation. Am. J. Transplant. 6: 254-261 (2006).
Moretta A. Natural killer cells and dendritic cells: rendezvous in abused tissues. Nat. Rev. Immunol. 2: 957-964 (2002). *
Moretta A, Bottino C, Sivori S, Marcenaro E, Castriconi R, Della Chiesa M, Carlomagno S, Augugliaro R, Nanni M, Vitale M, Millo R. Natural killer lymphocytes: "null cells" no more. Ital. J. Anat. Embryol. 106: 335-342 (2001).
Moretta A, Bottino C, Vitale M, Pende D, Cantoni C, Mingari MC, Biassoni R, Moretta L. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu. Rev. Immunol. 19: 197-223 (2001). *
Moretta A, Parolini S, Castriconi R, Bottino C, Vitale M, Sivori S, Millo R. Function and specificity of human natural killer cell receptors. Eur. J. Immunogenet. 24: 455-468 (1997).
Moretta L, Biassoni R, Bottino C, Cantoni C, Pende D, Mingari MC, Moretta A. Human NK cells and their receptors. Microbes Infect. 4: 1539-1544 (2002). *
Moretta L, Biassoni R, Bottino C, Mingari MC, Moretta A. Natural killer cells: a mystery no more. Scand. J. Immunol. 55: 229-232 (2002). *
Moretta L, Bottino C, Pende D, Castriconi R, Mingari MC, Moretta A. Surface NK receptors and their ligands on tumor cells. Semin. Immunol. 18: 151-158 (2006). *
Moretta L, Bottino C, Pende D, Mingari MC, Biassoni R, Moretta A. Human natural killer cells: their origin, receptors and function. Eur. J. Immunol. 32: 1205-1211 (2002). *
Moretta L, Bottino C, Pende D, Vitale M, Mingari MC, Moretta A. Human natural killer cells: molecular mechanisms controlling NK cell activation and tumor cell lysis. Immunol. Lett. 100: 7-13 (2005).
Moretta L, Bottino C, Pende D, Vitale M, Mingari MC, Moretta A. Different checkpoints in human NK-cell activation. Trends Immunol. 25: 670-676 (2004). *
Moretta L, Moretta A. Unravelling natural killer cell function: triggering and inhibitory human NK receptors. EMBO J. 23: 255-259 (2004). *
Morgan ME, Witteveen HJ, Sutmuller RP, de Vries RR, Toes RE. CD25(+) regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis. Hum. Immunol. 65: 1319-1327 (2004).
Mori L, De Libero G. Presentation of lipid antigens to T cells. Immunol. Lett. 117: 1-8 (2008).
Morice WG. The immunophenotypic attributes of NK cells and NK-cell lineage lymphoproliferative disorders. Am. J. Clin. Pathol. 127: 881-886 (2007).
Morling N, Andersen V, Fugger L, Georgsen J, Halberg P, Oxholm P, Odum N, Svejgaard A. Immunogenetics of rheumatoid arthritis and primary Sjogren's syndrome: DNA polymorphism of HLA class II genes. Dis. Markers 9: 289-296 (1991).
Morling N, Frentz G, Fugger L, Georgsen J, Jakobsen B, Odum N, Svejgaard A. DNA polymorphism of HLA class II genes in alopecia areata. Dis. Markers 9: 35-42 (1991).
Moroldo MB, Donnelly P, Saunders J, Glass DN, Giannini EH. Transmission disequilibrium as a test of linkage and association between HLA alleles and pauciarticular-onset juvenile rheumatoid arthritis. Arthritis Rheum. 41: 1620-1624 (1998). *
Morris GP, Allen PM. Cutting edge: highly alloreactive dual TCR T cells play a dominant role in graft-versus-host disease. J. Immunol. 182: 6639-6643 (2009).
Morris GP, Brown NK, Kong YC. Naturally-existing CD4(+)CD25(+)Foxp3(+) regulatory T cells are required for tolerance to experimental autoimmune thyroiditis induced by either exogenous or endogenous autoantigen. J. Autoimmun. 33: 68-76 (2009).
Morris SC, Heidorn SM, Herbert DR, Perkins C, Hildeman DA, Khodoun MV, Finkelman FD. Endogenously produced IL-4 nonredundantly stimulates CD8+ T cell proliferation. J. Immunol. 182: 1429-1438 (2009).
Moscoso J, Serrano-Vela JI, Arnaiz-Villena A. MHC-F polymorphism and evolution. Tissue Antigens 69 Suppl. 1: 136-139 (2007). *
Moscoso J, Serrano-Vela JI, Pacheco R, Arnaiz-Villena A. HLA-G, -E and -F: allelism, function and evolution. Transpl. Immunol. 17: 61-64 (2006).
Moser KL, Kelly JA, Lessard CJ, Harley JB. Recent insights into the genetic basis of systemic lupus erythematosus. Genes Immun. 10: 373-379 (2009).
Moss CX, Matthews SP, Lamont DJ, Watts C. Asparagine deamidation perturbs antigen presentation on class II MHC molecules. J. Biol. Chem. 280: 18498-18503 (2005). *
Mossner R, Beckmann I, Hallermann C, Neumann C, Reich K. Granulocyte colony-stimulating-factor-induced psoriasiform dermatitis resembles psoriasis with regard to abnormal cytokine expression and epidermal activation. Exp. Dermatol. 13: 340-346 (2004). *
Mostbock S, Catalfamo M, Tagaya Y, Schlom J, Sabzevari H. Acquisition of antigen presentasomes (APS), an MHC/costimulatory complex, is a check-point of memory T cell homeostasis. Blood 109: 2488-2495 (2007). *
Mothes T, Bendix U, Pfannschmidt C, Lehmann I. Effect of gliadin and other food peptides on expression of MHC class II molecules by HT-29 cells. Gut 36: 548-552 (1995). *
Moudgil KD, Sercarz EE. Understanding crypticity is the key to revealing the pathogenesis of autoimmunity. Trends Immunol. 26: 355-359 (2005). *
Mouries J, Moron G, Schlecht G, Escriou N, Dadaglio G, Leclerc C. Plasmacytoid dendritic cells efficiently cross-prime naive T cells in vivo after TLR activation. Blood 112: 3713-3722 (2008). *
Moustakas AK, Papadopoulos GK. Use of MHC II structural features in the design of vaccines for organ-specific autoimmune diseases. Curr. Pharm. Des. 15: 3262-3273 (2009).
Moustakas AK, Papadopoulos GK. Molecular properties of HLA-DQ alleles conferring susceptibility to or protection from insulin-dependent diabetes mellitus: keys to the fate of islet beta-cells. Am. J. Med. Genet. 115: 37-47 (2002).
Moustakas AK, van de Wal Y, Routsias J, Kooy YM, van Veelen P, Drijfhout JW, Koning F, Papadopoulos GK. Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes. Int. Immunol. 12: 1157-1166 (2000). *
Mouzaki A, Deraos S, Chatzantoni K. Advances in the treatment of autoimmune diseases; cellular activity, type-1/type-2 cytokine secretion patterns and their modulation by therapeutic peptides. Curr. Med. Chem. 12: 1537-1550 (2005).
Moxham VF, Karegli J, Phillips RE, Brown KL, Tapmeier TT, Hangartner R, Sacks SH, Wong W. Homeostatic proliferation of lymphocytes results in augmented memory-like function and accelerated allograft rejection. J. Immunol. 180: 3910-3918 (2008). *
Moza B, Varma AK, Buonpane RA, Zhu P, Herfst CA, Nicholson MJ, Wilbuer AK, Seth NP, Wucherpfennig KW, McCormick JK, Kranz DM, Sundberg EJ. Structural basis of T-cell specificity and activation by the bacterial superantigen TSST-1. EMBO J. 26: 1187-1197 (2007). *
Mozes E, Lovchik J, Zinger H, Singer DS. MHC class I expression regulates susceptibility to spontaneous autoimmune disease in (NZBxNZW)F1 mice. Lupus 14: 308-314 (2005).
Mrazek F, Holla LI, Hutyrova B, Znojil V, Vasku A, Kolek V, Welsh KI, Vacha J, du Bois RM, Petrek M. Association of tumour necrosis factor-alpha, lymphotoxin-alpha and HLA-DRB1 gene polymorphisms with Lofgren's syndrome in Czech patients with sarcoidosis. Tissue Antigens 65: 163-171 (2005). *
Muchamuel T, Basler M, Aujay MA, Suzuki E, Kalim KW, Lauer C, Sylvain C, Ring ER, Shields J, Jiang J, Shwonek P, Parlati F, Demo SD, Bennett MK, Kirk CJ, Groettrup M. A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis. Nat. Med. 15: 781-787 (2009). *
Muckenthaler MU, Rodrigues P, Macedo MG, Minana B, Brennan K, Cardoso EM, Hentze MW, De Sousa M. Molecular analysis of iron overload in beta2-microglobulin-deficient mice. Blood Cells Mol. Dis. 33: 125-131 (2004).
Mudhasani R, Fontes JD. Multiple interactions between BRG1 and MHC class II promoter binding proteins. Mol. Immunol. 42: 673-682 (2005). *
Mueller B, Lilley BN, Ploegh HL. SEL1L, the homologue of yeast Hrd3p, is involved in protein dislocation from the mammalian ER. J. Cell Biol. 175: 261-270 (2006). *
Mueller DL. Mechanisms maintaining peripheral tolerance. Nat. Immunol. 11: 21-27 (2010). *
Mueller RB, Skapenko A, Grunke M, Wendler J, Stuhlmuller B, Kalden JR, Schulze-Koops H. Regulation of myeloid cell function and major histocompatibility complex class II expression by tumor necrosis factor. Arthritis Rheum. 52: 451-460 (2005). *
Mueller RB, Skapenko A, Wendler J, Schuch F, Kalden JR, Schulze-Koops H. MHC class II expression on myeloid cells inversely correlates with disease progression in early rheumatoid arthritis. Rheumatology (Oxford) 46: 931-933 (2007). *
Muhanna N, Horani A, Doron S, Safadi R. Lymphocyte-hepatic stellate cell proximity suggests a direct interaction. Clin. Exp. Immunol. 148: 338-347 (2007). *
Muix� L, Alvarez I, Jaraquemada D. Chapter 6. Peptides presented in vivo by HLA-DR in thyroid autoimmunity. Adv. Immunol. 99C: 165-209 (2008).
Mukai T, Maeda Y, Tamura T, Matsuoka M, Tsukamoto Y, Makino M. Induction of cross-priming of naive CD8+ T lymphocytes by recombinant bacillus Calmette-Guerin that secretes heat shock protein 70-major membrane protein-II fusion protein. J. Immunol. 183: 6561-6568 (2009).
Mulcahy H, O'Rourke KP, Adams C, Molloy MG, O'Gara F. LST1 and NCR3 expression in autoimmune inflammation and in response to IFN-gamma, LPS and microbial infection. Immunogenetics 57: 893-903 (2006). *
Mulder A, Kardol MJ, Arn JS, Eijsink C, Franke ME, Schreuder GM, Haasnoot GW, Doxiadis II, Sachs DH, Smith DM, Claas FH. Human monoclonal HLA antibodies reveal interspecies crossreactive swine MHC class I epitopes relevant for xenotransplantation. Mol. Immunol. Nov 19 [Epub ahead of print] (2009). *
Mulder IE, Schmidt B, Stokes CR, Lewis M, Bailey M, Aminov RI, Prosser JI, Gill BP, Pluske JR, Mayer CD, Musk C, Kelly D. Environmentally-acquired bacteria influence microbial diversity and natural innate immune responses at gut surfaces. BMC Biol. 7: 79 (2009). *
Muller JY, Clemenceau S, Foncin JF, Salmon D, Halle L, Castellano F, Salmon C. Absence of linkage between Alzheimer's disease and the HLA system. C. R. Acad. Sci. III. 303: 105-108 (1986).
Muller M, Fink K, Geisel J, Kahl F, Jilge B, Reimann J, Mach N, Autenrieth IB, Frick JS. Intestinal colonization of IL-2 deficient mice with non-colitogenic B. vulgatus prevents DC maturation and T-cell polarization. PLoS ONE 3: e2376 (2008). *
Muller-Hilke B, Mitchison NA. The role of HLA promoters in autoimmunity. Curr. Pharm. Des. 12: 3743-3752 (2006).
Multhoff G. Heat shock proteins in immunity. Handb. Exp. Pharmacol. 172: 279-304 (2006).
Multhoff G, Botzler C, Issels R. The role of heat shock proteins in the stimulation of an immune response. Biol. Chem. 379: 295-300 (1998).
Mumtaz M, Lofgren S, Hugander A, Dimberg J. Polymorphism in MHC class II transactivator gene is not associated with susceptibility to colorectal cancer in Swedish patients. Anticancer Res. 28: 1789-2791 (2008).
Muntasell A, Carrascal M, Alvarez I, Serradell L, van Veelen P, Verreck FA, Koning F, Abian J, Jaraquemada D. Dissection of the HLA-DR4 peptide repertoire in endocrine epithelial cells: strong influence of invariant chain and HLA-DM expression on the nature of ligands. J. Immunol. 173: 1085-1093 (2004). *
Munthe LA, Corthay A, Os A, Zangani M, Bogen B. Systemic autoimmune disease caused by autoreactive B cells that receive chronic help from Ig v region-specific T cells. J. Immunol. 175: 2391-2400 (2005). *
Munz C. Antigen processing via autophagy-not only for MHC class II presentation anymore? Curr. Opin. Immunol. Feb 8 [Epub ahead of print] (2010).
Munz C. Autophagy and antigen presentation. Cell. Microbiol. 8: 891-898 (2006). *
Munz C. Enhancing immunity through autophagy. Annu. Rev. Immunol. 27: 423-449 (2009). *
Munz C, Lunemann JD, Getts MT, Miller SD. Antiviral immune responses: triggers of or triggered by autoimmunity? Nat. Rev. Immunol. 9: 246-258 (2009). *
Murakami T, Cosimi AB, Kawai T. Mixed chimerism to induce tolerance: lessons learned from nonhuman primates. Transplant. Rev. (Orlando) 23: 19-24 (2009).
Muranski P, Boni A, Antony PA, Cassard L, Irvine KR, Kaiser A, Paulos CM, Palmer DC, Touloukian CE, Ptak K, Gattinoni L, Wrzesinski C, Hinrichs CS, Kerstann K, Feigenbaum L, Chan CC, Restifo NP. Tumor-specific Th17-polarized cells eradicate large established melanoma. Blood 112: 362-373 (2008). *
Muraoka M, Hasegawa H, Kohno M, Inoue A, Miyazaki T, Terada M, Nose M, Yasukawa M. IK cytokine ameliorates the progression of lupus nephritis in MRL/lpr mice. Arthritis Rheum. 54: 3591-3600 (2006). *
Murata S, Sasaki K, Kishimoto T, Niwa S, Hayashi H, Takahama Y, Tanaka K. Regulation of CD8+ T cell development by thymus-specific proteasomes. Science 316: 1349-1353 (2007). *
Murdaca G, Contini P, Setti M, Cagnati P, Villa R, Lantieri F, Indiveri F, Puppo F. Behavior of serum human major histocompatibility complex class I antigen levels in human immunodeficiency virus-infected patients during antiretroviral therapy: correlation with clinical outcome. Hum. Immunol. 68: 894-900 (2007).
Muro Y, Ogawa Y, Sugiura K, Tomita Y. HLA-associated production of anti-DFS70/LEDGF autoantibodies and systemic autoimmune disease. J. Autoimmun. 26: 252-257 (2006).
Muroi S, Naoe Y, Miyamoto C, Akiyama K, Ikawa T, Masuda K, Kawamoto H, Taniuchi I. Cascading suppression of transcriptional silencers by ThPOK seals helper T cell fate. Nat. Immunol. 9: 1113-1121 (2008). *
Murphy AC, Lalor SJ, Lynch MA, Mills KH. Infiltration of Th1 and Th17 cells and activation of microglia in the CNS during the course of experimental autoimmune encephalomyelitis. Brain Behav. Immun. Feb 4 [Epub ahead of print] (2010).
Murugaiyan G, Martin S, Saha B. Levels of CD40 expression on dendritic cells dictate tumour growth or regression. Clin. Exp. Immunol. 149: 194-202 (2007). *
Mutschlechner S, Egger M, Briza P, Wallner M, Lackner P, Karle A, Vogt AB, Fischer GF, Bohle B, Ferreira F. Naturally processed T-cell-activating peptides of the major birch pollen allergen. J. Allergy Clin. Immunol. Feb 2 [Epub ahead of print] (2010). *
Na SY, Cao Y, Toben C, Nitschke L, Stadelmann C, Gold R, Schimpl A, Hunig T. Naive CD8 T-cells initiate spontaneous autoimmunity to a sequestered model antigen of the central nervous system. Brain 131: 2353-2365 (2008).
Na SY, Eujen H, Gobel K, Meuth SG, Martens K, Wiendl H, Hunig T. Antigen-specific blockade of lethal CD8 T-cell mediated autoimmunity in a mouse model of multiple sclerosis. J. Immunol. 182: 6569-6575 (2009).
Nabozny GH, Baisch JM, Cheng S, Cosgrove D, Griffiths MM, Luthra HS, David CS. HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis. J. Exp. Med. 183: 27-37 (1996). *
Nagaraju K. Role of major histocompatibility complex class I molecules in autoimmune myositis. Curr. Opin. Rheumatol. 17: 725-730 (2005).
Nagata T, Weiss EH, Abe K, Kitagawa K, Ando A, Yara-Kikuti Y, Seldin MF, Ozato K, Inoko H, Taketo M. Physical mapping of the retinoid X receptor B gene in mouse and human. Immunogenetics 41: 83-90 (1995).
Nagayama Y. Animal models of Graves' hyperthyroidism. Endocr. J. 52: 385-394 (2005). *
Nair MG, Guild KJ, Du Y, Zaph C, Yancopoulos GD, Valenzuela DM, Murphy A, Stevens S, Karow M, Artis D. Goblet cell-derived resistin-like molecule beta augments CD4+ T cell production of IFN-gamma and infection-induced intestinal inflammation. J. Immunol. 181: 4709-4715 (2008). *
Nair RP, Stuart P, Henseler T, Jenisch S, Chia NV, Westphal E, Schork NJ, Kim J, Lim HW, Christophers E, Voorhees JJ, Elder JT. Localization of psoriasis-susceptibility locus PSORS1 to a 60-kb interval telomeric to HLA-C. Am. J. Hum. Genet. 66: 1833-1844 (2000). *
Nair RP, Stuart PE, Nistor I, Hiremagalore R, Chia NV, Jenisch S, Weichenthal M, Abecasis GR, Lim HW, Christophers E, Voorhees JJ, Elder JT. Sequence and haplotype analysis supports HLA-C as the psoriasis susceptibility 1 gene. Am. J. Hum. Genet. 78: 827-851 (2006). *
Najafian N, Sayegh MH. CTLA4-Ig: a novel immunosuppressive agent. Expert Opin. Investig. Drugs 9: 2147-2157 (2000).
Nakamura MC, Nakamura RM. Contemporary concepts of autoimmunity and autoimmune diseases. J. Clin. Lab. Anal. 6: 275-289 (1992).
Nakamura O. Children's immunology, what can we learn from animal studies (1): decidual cells induce specific immune system of feto-maternal interface. J. Toxicol. Sci. 34: SP331-SP339 (2009). *
Nakanishi K, Komatsu Y, Kogawa N, Matsushita H. Analysis of eluted peptides from type 1 diabetes-susceptible HLA class II molecules identified novel islet protein, heparin/heparan sulfate-interacting protein. Biochem. Biophys. Res. Commun. 329: 356-361 (2005). *
Nakano N, Nishiyama C, Yagita H, Koyanagi A, Akiba H, Chiba S, Ogawa H, Okumura K. Notch signaling confers antigen-presenting cell functions on mast cells. J. Allergy Clin. Immunol. 123: 74-81.e1 (2009). *
Nakano T, Goto S, Lai CY, Hsu LW, Ono K, Kawamoto S, Lin YC, Kao YH, Chiang KC, Ohmori N, Goto T, Sato S, Tu CH, Jawan B, Cheng YF, Chen CL. Impact of vaccine therapy using nuclear histone H1 on allograft survival in experimental organ transplantation. Transpl. Immunol. 17: 147-152 (2007).
Nakano T, Ono K, Goto S, Lai CY, Hsu LW, Kawamoto S, Lin YC, Kao YH, Chiang KC, Ohmori N, Goto T, Sato S, Jawan B, Cheng YF, Chen CL. Histone H1 vaccine therapy for overcoming acute rejection in experimental organ transplantation. Transplant. Proc. 38: 3247-3248 (2006). *
Nakayama M, Abiru N, Moriyama H, Babaya N, Liu E, Miao D, Yu L, Wegmann DR, Hutton JC, Elliott JF, Eisenbarth GS. Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature 435: 220-223 (2005). *
Nakken B, Jonsson R, Brokstad KA, Omholt K, Nerland AH, Haga HJ, Halse AK. Associations of MHC class II alleles in Norwegian primary Sjogren's syndrome patients: implications for development of autoantibodies to the Ro52 autoantigen. Scand. J. Immunol. 54: 428-433 (2001). *
Nalabolu SR, Shukla H, Nallur G, Parimoo S, Weissman SM. Genes in a 220-kb region spanning the TNF cluster in human MHC. Genomics 31: 215-222 (1996).
Nalbandian G, Kovats S. Understanding sex biases in immunity: effects of estrogen on the differentiation and function of antigen-presenting cells. Immunol. Res. 31: 91-106 (2005). *
Namazi MR. Cetirizine and allopurinol as novel weapons against cellular autoimmune disorders. Int. Immunopharmacol. 4: 349-353 (2004).
Namo Cury A, Longui CA, Kochi C, Calliari LE, Scalissi N, Salles JE, Neves Rocha M, Barbosa de Melo M, Rezende Melo M, Monte O. Graves' disease in Brazilian children and adults: lack of genetic association with CTLA-4 +49A>G polymorphism. Horm. Res. 70: 36-41 (2008).
Nandakumar KS, Holmdahl R. A genetic contamination in MHC-congenic mouse strains reveals a locus on chromosome 10 that determines autoimmunity and arthritis susceptibility. Eur. J. Immunol. 35: 1275-1282 (2005). *
Nanno M, Shiohara T, Yamamoto H, Kawakami K, Ishikawa H. gammadelta T cells: firefighters or fire boosters in the front lines of inflammatory responses. Immunol. Rev. 215: 103-113 (2007). *
Nano R, Capelli E, Facoetti A, Benericetti E. Immunobiological and experimental aspects of malignant astrocytoma. Anticancer Res. 29: 2461-2465 (2009).
Naranjo F, Marquez I, Gendzekhadze K, Zhang S, Fernandez-Mestre M, Yegres F, Richard-Yegres N, Navas T, Montagnani S, Ogando V, Layrisse Z. Human leukocyte antigen class I and MICA haplotypes in a multicase family with Cladophialophora carrionii chromoblastomycosis. Tissue Antigens 68: 287-292 (2006). *
Narayan K, Perkins EM, Murphy GE, Dalai SK, Edidin M, Subramaniam S, Sadegh-Nasseri S. Staphylococcal enterotoxin A induces small clusters of HLA-DR1 on B cells. PLoS One 4: e6188 (2009). *
Narayan K, Su KW, Chou CL, Khoruzhenko S, Sadegh-Nasseri S. HLA-DM mediates peptide exchange by interacting transiently and repeatedly with HLA-DR1. Mol. Immunol. 46: 3157-3162 (2009). *
Narzi D, Winkler K, Saidowsky J, Misselwitz R, Ziegler A, Bockmann RA, Alexiev U. Molecular determinants of major histocompatibility complex class I complex stability: shaping antigenic features through short- and long-range electrostatic interactions. J. Biol. Chem. 283: 23093-23103 (2008). *
Nasef A, Mathieu N, Chapel A, Frick J, Francois S, Mazurier C, Boutarfa A, Bouchet S, Gorin NC, Thierry D, Fouillard L. Immunosuppressive effects of mesenchymal stem cells: involvement of HLA-G. Transplantation 84: 231-237 (2007).
Natarajan K, Dimasi N, Wang J, Margulies DH, Mariuzza RA. MHC class I recognition by Ly49 natural killer cell receptors. Mol. Immunol. 38: 1023-1027 (2002). *
Natarajan K, Dimasi N, Wang J, Mariuzza RA, Margulies DH. Structure and function of natural killer cell receptors: multiple molecular solutions to self, nonself discrimination. Annu. Rev. Immunol. 20: 853-885 (2002). *
Natarajan K, Li H, Mariuzza RA, Margulies DH. MHC class I molecules, structure and function. Rev. Immunogenet. 1: 32-46 (1999).
Natividad A, Hanchard N, Holland MJ, Mahdi OS, Diakite M, Rockett K, Jallow O, Joof HM, Kwiatkowski DP, Mabey DC, Bailey RL. Genetic variation at the TNF locus and the risk of severe sequelae of ocular Chlamydia trachomatis infection in Gambians. Genes Immun. 8: 288-295 (2007). *
Naugler C, Liwski R. An evolutionary approach to major histocompatibility diversity based on allele supertypes. Med. Hypotheses 70: 933-937 (2008).
Naumova E, Pawelec G, Ivanova M, Constantinescu I, Bogunia-Kubik K, Lange A, Qguz F, Carin M. 14th International HLA and Immunogenetics Workshop: report on the immunogenetics of aging. Tissue Antigens 69 Suppl. 1: S304-S310 (2007).
Nedjic J, Aichinger M, Mizushima N, Klein L. Macroautophagy, endogenous MHC II loading and T cell selection: the benefits of breaking the rules. Curr. Opin. Immunol. 21: 92-97 (2009).
Needham M, Corbett A, Day T, Christiansen F, Fabian V, Mastaglia FL. Prevalence of sporadic inclusion body myositis and factors contributing to delayed diagnosis. J. Clin. Neurosci. 15: 1350-1353 (2008).
Needham M, Mastaglia FL. Sporadic inclusion body myositis: a continuing puzzle. Neuromuscul. Disord. 18: 6-16 (2008).
Needham M, Mastaglia FL, Garlepp MJ. Genetics of inclusion-body myositis. Muscle Nerve 35: 549-561 (2007).
Neethling FA, Ramakrishna V, Keler T, Buchli R, Weidanz JA. Assessing vaccine potency using TCRmimic antibodies. Vaccine 26: 3092-3102 (2008).
Neighbors M, Hartley SB, Xu X, Castro AG, Bouley DM, O'Garra A. Breakpoints in immunoregulation required for Th1 cells to induce diabetes. Eur. J. Immunol. 36: 2315-2323 (2006). *
Neijssen J, Herberts C, Drijfhout JW, Reits E, Janssen L, Neefjes J. Cross-presentation by intercellular peptide transfer through gap junctions. Nature 434: 83-88 (2005). *
Nejentsev S, Howson JM, Walker NM, Szeszko J, Field SF, Stevens HE, Reynolds P, Hardy M, King E, Masters J, Hulme J, Maier LM, Smyth D, Bailey R, Cooper JD, Ribas G, Campbell RD, Clayton DG, Todd JA; The Wellcome Trust Case Control Consortium. Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature 450: 887-892 (2007). *
Nejentsev S, Reijonen H, Adojaan B, Kovalchuk L, Sochnevs A, Schwartz EI, Akerblom HK, Ilonen J. The effect of HLA-B allele on the IDDM risk defined by DRB1*04 subtypes and DQB1*0302. Diabetes 46: 1888-1892 (1997).
Nelson CA, Fremont DH. Structural principles of MHC class II antigen presentation. Rev. Immunogenet. 1: 47-59 (1999).
Nepom GT. The role of the DR4 shared epitope in selection and commitment of autoreactive T cells in rheumatoid arthritis. Rheum. Dis. Clin. North Am. 27: 305-315 (2001).
Nepom GT. Determinants of genetic susceptibility in HLA-associated autoimmune disease. Clin. Immunol. Immunopathol. 53: S53-S62 (1989).
Nepom GT, Erlich H. MHC class-II molecules and autoimmunity. Annu. Rev. Immunol. 9: 493-525 (1991). *
Nepom GT, Hansen JA, Nepom BS. The molecular basis for HLA class II associations with rheumatoid arthritis. J. Clin. Immunol. 7: 1-7 (1987).
Nepom GT, Kwok WW. Molecular basis for HLA-DQ associations with IDDM. Diabetes 47: 1177-1184 (1998). *
Neri TM, Cavestro GM, Seghini P, Zanelli PF, Zanetti A, Savi M, Podda M, Zuin M, Colombo M, Floreani A, Rosina F, Bianchi Porro G, Strazzabosco M, Okolicsanyi L. Novel association of HLA-haplotypes with primary sclerosing cholangitis (PSC) in a southern European population. Dig. Liver Dis. 35: 571-576 (2003).
Neumann F, Sturm C, Hulsmeyer M, Dauth N, Guillaume P, Luescher IF, Pfreundschuh M, Held G. Fab antibodies capable of blocking T cells by competitive binding have the identical specificity but a higher affinity to the MHC-peptide-complex than the T-cell receptor. Immunol. Lett. 125: 86-92 (2009).
Neumann J, Koch N. A novel domain on HLA-DRbeta chain regulates the chaperone role of the invariant chain. J. Cell. Sci. 119: 4207-4214 (2006). *
Neumann J, Koch N. Assembly of major histocompatibility complex class II subunits with invariant chain. FEBS Lett. 579: 6055-6059 (2005). *
Neville MJ, Campbell RD. A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC. J. Immunol. 162: 4745-4754 (1999). *
Newman B, Silverberg MS, Gu X, Zhang Q, Lazaro A, Steinhart AH, Greenberg GR, Griffiths AM, McLeod RS, Cohen Z, Fernandez-Vina M, Amos CI, Siminovitch K. CARD15 and HLA DRB1 alleles influence susceptibility and disease localization in Crohn's disease. Am. J. Gastroenterol. 99: 306-315 (2004). *
Newman KC, Korbel DS, Hafalla JC, Riley EM. Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog. 2: e118 (2006). *
Newman WG, Zhang Q, Liu X, Walker E, Ternan H, Owen J, Johnson B, Greer W, Mosher DP, Maksymowych WP, Bykerk VP, Keystone EC, Amos CI, Siminovitch KA. Rheumatoid arthritis association with the FCRL3 -169C polymorphism is restricted to PTPN22 1858T-homozygous individuals in a Canadian population. Arthritis Rheum. 54: 3820-3827 (2006). *
Newton J, Brown MA, Milicic A, Ackerman H, Darke C, Wilson JN, Wordsworth BP, Kwiatkowski D. The effect of HLA-DR on susceptibility to rheumatoid arthritis is influenced by the associated lymphotoxin alpha-tumor necrosis factor haplotype. Arthritis Rheum. 48: 90-96 (2003). *
Newton JL, Harney SM, Timms AE, Sims AM, Rockett K, Darke C, Wordsworth BP, Kwiatkowski D, Brown MA. Dissection of class III major histocompatibility complex haplotypes associated with rheumatoid arthritis. Arthritis Rheum. 50: 2122-2129 (2004). *
Newton JL, Harney SM, Wordsworth BP, Brown MA. A review of the MHC genetics of rheumatoid arthritis. Genes Immun. 5: 151-157 (2004). *
Ng B, Yang F, Huston DP, Yan Y, Yang Y, Xiong Z, Peterson LE, Wang H, Yang XF. Increased noncanonical splicing of autoantigen transcripts provides the structural basis for expression of untolerized epitopes. J. Allergy Clin. Immunol. 114: 1463-1470 (2004).
Nguyen T, Liu XK, Zhang Y, Dong C. BTNL2, a butyrophilin-like molecule that functions to inhibit T cell activation. J. Immunol. 176: 7354-7360 (2006). *
Nguyen van Binh P, Duc HT. Epitopes of the class I major histocompatibility complex (MHC-I) recognized in the syngeneic or allogeneic context predominantly linked to antigenic peptide loading to its binding groove. Clin. Exp. Immunol. 145: 372-379 (2006). *
Niazi KR, Ochoa MT, Sieling PA, Rooke NE, Peter AK, Mollahan P, Dickey M, Rabizadeh S, Rea TH, Modlin RL. Activation of human CD4(+) T cells by targeting MHC class II epitopes to endosomal compartments using human CD1 tail sequences. Immunology 122: 522-531 (2007). *
Nickerson CL, Luthra HS, David CS. Role of enterobacteria and HLA-B27 in spondyloarthropathies: studies with transgenic mice. Ann. Rheum. Dis. 49: 426-433 (1990).
Nicknam MH, Mahmoudi M, Amirzargar AA, Ganjalikhani Hakemi M, Khosravi F, Jamshidi AR, Amirkhani A, Ansaripour B, Pourpak Z, Moin M, Nikbin B. Determination of HLA-B27 subtypes in Iranian patients with ankylosing spondylitis. Iran. J. Allergy Asthma Immunol. 7: 19-24 (2008).
Nickoloff BJ, Bonish B, Huang BB, Porcelli SA. Characterization of a T cell line bearing natural killer receptors and capable of creating psoriasis in a SCID mouse model system. J. Dermatol. Sci. 24: 212-225 (2000).
Nicoletti C, Temblay JN, Regoli M, Bertelli E, Man AL. Differential regulation of dendritic cell-T cell cross talk in the gut-associated lymphoid tissue. Mol. Immunol. 43: 542-549 (2006). *
Niederkorn JY. Mechanisms of immune privilege in the eye and hair follicle. J. Investig. Dermatol. Symp. Proc. 8: 168-172 (2003). *
Nielsen M, Lundegaard C, Blicher T, Lamberth K, Harndahl M, Justesen S, Roder G, Peters B, Sette A, Lund O, Buus S. NetMHCpan, a method for quantitative predictions of peptide binding to any HLA-A and -B locus protein of known sequence. PLoS ONE 2: e796 (2007). *
Nielsen M, Lundegaard C, Blicher T, Peters B, Sette A, Justesen S, Buus S, Lund O. Quantitative predictions of peptide binding to any HLA-DR molecule of known sequence: NetMHCIIpan. PLoS Comput. Biol. 4: e1000107 (2008). *
Nielsen M, Lundegaard C, Lund O. Prediction of MHC class II binding affinity using SMM-align, a novel stabilization matrix alignment method. BMC Bioinformatics 8: 238 (2007). *
Niemeyer P, Kornacker M, Mehlhorn A, Seckinger A, Vohrer J, Schmal H, Kasten P, Eckstein V, Sudkamp NP, Krause U. Comparison of immunological properties of bone marrow stromal cells and adipose tissue-derived stem cells before and after osteogenic differentiation in vitro. Tissue Eng. 13: 111-121 (2007).
Niesen MI, Blanck G. Rescue of major histocompatibility-DR surface expression in retinoblastoma-defective, non-small cell lung carcinoma cells by the MS-275 histone deacetylase inhibitor. Biol. Pharm. Bull. 32: 480-482 (2009). *
Niess JH, Adler G. Enteric flora expands gut lamina propria CX3CR1+ dendritic cells supporting inflammatory immune responses under normal and inflammatory conditions. J. Immunol. Jan 20 [Epub ahead of print] (2010).
Niikura M, Kim T, Hunt HD, Burnside J, Morgan RW, Dodgson JB, Cheng HH. Marek's disease virus up-regulates major histocompatibility complex class II cell surface expression in infected cells. Virology 359: 212-219 (2007). *
Nikitina-Zake L, Ghaderi M, Park Y, Babu S, Eisenbarth G, Sanjeevi CB. MICA gene polymorphism in HBDI multiplex families. Ann. N. Y. Acad. Sci. 1037: 150-156 (2004). *
Nikolich-Zugich J, Fremont DH, Miley MJ, Messaoudi I. The role of MHC polymorphism in anti-microbial resistance. Microbes Infect. 6: 501-512 (2004). *
Nikolich-Zugich J, Slifka MK, Messaoudi I. The many important facets of T-cell repertoire diversity. Nat. Rev. Immunol. 4: 123-132 (2004). *
Nikulina M, Habich C, Flohe SB, Scott FW, Kolb H. Wheat gluten causes dendritic cell maturation and chemokine secretion. J. Immunol. 173: 1925-1933 (2004).
Ninkovic T, Kinarsky L, Engelmann K, Pisarev V, Sherman S, Finn OJ, Hanisch FG. Identification of O-glycosylated decapeptides within the MUC1 repeat domain as potential MHC class I (A2) binding epitopes. Mol. Immunol. 47: 131-140 (2009). *
Nino-Soto MI, Jafari Jozani R, Bridle B, Mallard BA. Analysis of gene expression patterns by microarray hybridization in blood mononuclear cells of SLA-DRB1 defined Canadian Yorkshire pigs. BMC Res. Notes 1: 31 (2008). *
Nishimoto H, Yamada G, Mizuno M, Tsuji T. Immunoelectron microscopic localization of MHC class 1 and 2 antigens on bile duct epithelial cells in patients with primary biliary cirrhosis. Acta Med. Okayama 48: 317-322 (1994).
Nishimura Y. Binding-peptide motifs of HLA class II molecules susceptible to autoimmune diseases. Nippon Rinsho 55: 1384-1396 (1997).
Nishimura Y, Oiso M, Fujisao S, Kanai T, Kira J, Chen YZ, Matsushita S. Peptide-based molecular analyses of HLA class II-associated susceptibility to autoimmune diseases. Int. Rev. Immunol. 17: 229-262 (1998).
Nishio A, Keeffe EB, Gershwin ME. Immunopathogenesis of primary biliary cirrhosis. Semin. Liver Dis. 22: 291-302 (2002). *
Nishiyama M, Takahashi M, Manaka KC, Roosihermiatie B, Kuriyama T, Nakae K. Research report: frequencies of MICA gene polymorphism: a comparison between Indonesians on Bacan Island and suburban Japanese. Southeast Asian J. Trop. Med. Public Health 35: 195-201 (2004).
Nishiyama M, Takahashi M, Manaka KI, Suzuki S, Saito M, Nakae K. Microsatellite polymorphisms of the MICA gene among Japanese patients with Behcet's disease. Can. J. Ophthalmol. 41: 210-215 (2006). *
Nishiyama Y, Hamada H, Nonaka S, Yamamoto H, Nanno M, Katayama Y, Takahashi H, Ishikawa H. Homeostatic regulation of intestinal villous epithelia by B lymphocytes. J. Immunol. 168: 2626-2633 (2002). *
Nistico L, Buzzetti R, Pritchard LE, Van der Auwera B, Giovannini C, Bosi E, Larrad MT, Rios MS, Chow CC, Cockram CS, Jacobs K, Mijovic C, Bain SC, Barnett AH, Vandewalle CL, Schuit F, Gorus FK, Tosi R, Pozzilli P, Todd JA. The CTLA-4 gene region of chromosome 2q33 is linked to, and associated with, type 1 diabetes. Belgian Diabetes Registry. Hum. Mol. Genet. 5: 1075-1080 (1996). *
Nitta T, Murata S, Sasaki K, Fujii H, Ripen AM, Ishimaru N, Koyasu S, Tanaka K, Takahama Y. Thymoproteasome shapes immunocompetent repertoire of CD8(+) T cells. Immunity Dec 30 [Epub ahead of print] (2009). *
Niu N, Laufer T, Homer RJ, Cohn L. Cutting edge: limiting MHC class II expression to dendritic cells alters the ability to develop Th2-dependent allergic airway inflammation. J. Immunol. 183: 1523-1527 (2009).
No authors listed. In this issue. Eur. J. Immunol. 39: 2942-2943 (2009). *
No authors listed. In this issue. Eur. J. Immunol. 40: 6-7 (2009). *
No authors listed. In this issue. Eur. J. Immunol. 39: 1690-1691 (2009).
No authors listed. In this issue. Eur. J. Immunol. 38: 321-322 (2008). *
No authors listed. In this issue. Eur. J. Immunol. 39: 919-920 (2009).
No authors listed. In this issue. Eur. J. Immunol. 39: 628-629 (2009). *
No authors listed. In this issue. Eur. J. Immunol. 38: 1179-1180 (2008). *
Noble A, Giorgini A, Leggat JA. Cytokine-induced IL-10-secreting CD8 T cells represent a phenotypically distinct suppressor T-cell lineage. Blood 107: 4475-4483 (2006). *
Noguchi H, Hanai T, Honda H, Harrison LC, Kobayashi T. Fuzzy neural network-based prediction of the motif for MHC class II binding peptides. J. Biosci. Bioeng. 92: 227-231 (2001). *
Nolan D, Gaudieri S, Mallal S. Host genetics and viral infections: immunology taught by viruses, virology taught by the immune system. Curr. Opin. Immunol. 18: 413-421 (2006).
Nomi T, Sho M, Akahori T, Kanehiro H, Nakajima Y. Protective effect of prostaglandin E2 receptors EP2 and EP4 in alloimmune response in vivo. Transplant. Proc. 38: 3209-3210 (2006). *
Nomura E, Sato M, Suemizu H, Watanabe T, Kimura T, Yabuki K, Goto K, Ito N, Bahram S, Inoko H, Mizuki N, Ohno S, Kimura M. Hyperkeratosis and leukocytosis in transgenic mice carrying MHC class I chain-related gene B (MICB). Tissue Antigens 61: 300-307 (2003). *
Norman PJ, Abi-Rached L, Gendzekhadze K, Hammond JA, Moesta AK, Sharma D, Graef T, McQueen KL, Guethlein LA, Carrington CV, Chandanayingyong D, Chang YH, Cresp� C, Saruhan-Direskeneli G, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, et al. Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes. Genome Res. 19: 757-769 (2009). *
Norman PJ, Abi-Rached L, Gendzekhadze K, Korbel D, Gleimer M, Rowley D, Bruno D, Carrington CV, Chandanayingyong D, Chang YH, Crespi C, Saruhan-Direskeneli G, Fraser PA, Hameed K, Kamkamidze G, Koram KA, Layrisse Z, Matamoros N, Mila J, Park MH, et al. Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans. Nat. Genet. 39: 1092-1099 (2007). *
Norris S, Kondeatis E, Collins R, Satsangi J, Clare M, Chapman R, Stephens H, Harrison P, Vaughan R, Donaldson P. Mapping MHC-encoded susceptibility and resistance in primary sclerosing cholangitis: the role of MICA polymorphism. Gastroenterology 120: 1475-1482 (2001). *
Nosikov VV, Seregin IuA. Molecular genetics of type 1 diabetes mellitus: achievements and future trends. Mol. Biol. (Mosk.) 42: 867-879 (2008).
Novitsky YW, Kercher KW, Czerniach DR, Litwin DE. Watermelon stomach: pathophysiology, diagnosis, and management. J. Gastrointest. Surg. 7: 652-661 (2003).
Novota P, Cejkova P, Cerna M, Andel M. Genetic risk factors in autoimmune diabetes mellitus, their significance and function. Cas. Lek. Cesk. 143: 159-163 (2004).
Novota P, Kolesar L, Slavcev A, Cerna M. Fluorescence-based automated fragment analysis of microsatellite polymorphism within the transmembrane region of the MIC-A gene. Folia Biol. (Praha) 50: 21-23 (2004).
Novotny MV, Soini HA, Koyama S, Wiesler D, Bruce KE, Penn DJ. Chemical identification of MHC-influenced volatile compounds in mouse urine. I: Quantitative proportions of major chemosignals. J. Chem. Ecol. 33: 417-434 (2007).
Nowak I, Pajtasz-Piasecka E, Chmielowski B, Ignatowicz L, Kusnierczyk P. The specific T-cell response to antigenic peptides is influenced by bystander peptides. Cell. Mol. Biol. Lett. 11: 70-79 (2006). *
Nowak J, Kalinka-Warzocha E, Juszczynski P, Mika-Witkowska R, Zajko M, Graczyk-Pol E, Coiffier B, Salles G, Warzocha K. Haplotype-specific pattern of association of human major histocompatibility complex with non-Hodgkin's lymphoma outcome. Tissue Antigens 71: 16-26 (2008). *
Nozell S, Ma Z, Wilson C, Shah R, Benveniste EN. Class II MHC transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression. J. Biol. Chem. 279: 38577-38589 (2004). *
Nunes M, Peelman L, Vaiman M, Bourgeaux N, Chardon P. Characterization of six new loci within the swine major histocompatibility complex class III region. Mamm. Genome 5: 616-622 (1994).
Nunez C, Alecsandru DM, Mendoza JL, Urcelay E, Diaz-Rubio M, de la Concha EG, Martinez A. Genetic markers linked to rheumatoid arthritis are also strongly associated with articular manifestations in ulcerative colitis patients. Hum. Immunol. 67: 324-330 (2006).
O'Brien C, Flower DR, Feighery C. Peptide length significantly influences in vitro affinity for MHC class II molecules. Immunome Res. 4: 6 (2008). *
O'Brien KP, Holm SJ, Nilsson S, Carlen L, Rosenmuller T, Enerback C, Inerot A, Stahle-Backdahl M. The HCR gene on 6p21 is unlikely to be a psoriasis susceptibility gene. J. Invest. Dermatol. 116: 750-754 (2001). *
O'Doherty C, Hawkins S, Rooney M, Vandenbroeck K. The MHC2TA-168A/G and +1614G/C polymorphisms and risk for multiple sclerosis or chronic inflammatory arthropathies. Tissue Antigens 70: 247-251 (2007). *
O'Donnell BF, O'Neill CM, Francis DM, Niimi N, Barr RM, Barlow RJ, Kobza Black A, Welsh KI, Greaves MW. Human leucocyte antigen class II associations in chronic idiopathic urticaria. Br. J. Dermatol. 140: 853-858 (1999). *
O'Hanlon TP, Carrick DM, Targoff IN, Arnett FC, Reveille JD, Carrington M, Gao X, Oddis CV, Morel PA, Malley JD, Malley K, Shamim EA, Rider LG, Chanock SJ, Foster CB, Bunch T, Blackshear PJ, Plotz PH, Love LA, Miller FW. Immunogenetic risk and protective factors for the idiopathic inflammatory myopathies: distinct HLA-A, -B, -Cw, -DRB1, and -DQA1 allelic profiles distinguish European American patients with different myositis autoantibodies. Medicine (Baltimore) 85: 111-127 (2006).
O'Keeffe J, Mills K, Jackson J, Feighery C. T cell proliferation, MHC class II restriction and cytokine products of gliadin-stimulated peripheral blood mononuclear cells (PBMC). Clin. Exp. Immunol. 117: 269-276 (1999). *
O'Keeffe M, Brodnicki TC, Fancke B, Vremec D, Morahan G, Maraskovsky E, Steptoe R, Harrison LC, Shortman K. Fms-like tyrosine kinase 3 ligand administration overcomes a genetically determined dendritic cell deficiency in NOD mice and protects against diabetes development. Int. Immunol. 17: 307-314 (2005). *
O'Shaughnessy MJ, Chen ZM, Gramaglia I, Taylor PA, Panoskaltsis-Mortari A, Vogtenhuber C, Palmer E, Grader-Beck T, Boussiotis VA, Blazar BR. Elevation of intracellular cyclic AMP in alloreactive CD4(+) T cells induces alloantigen-specific tolerance that can prevent GVHD lethality in vivo. Biol. Blood Marrow Transplant. 13: 530-542 (2007).
O'Shea H, Yousaf N, Altmann D, Fehervari Z, Tonks P, Hetherington C, Harach S, Bland C, Cooke A, Lund T. Effect of X- and Y-box deletions on the development of diabetes in H-2Ealpha-chain transgenic nonobese diabetic mice. Scand. J. Immunol. 63: 17-25 (2006). *
O'Sullivan BP, Zwerdling RG, Dorkin HL, Comeau AM, Parad R. Early pulmonary manifestation of cystic fibrosis in children with the DeltaF508/R117H-7T genotype. Pediatrics 118: 1260-1265 (2006). *
Obermajer N, Doljak B, Kos J. Cysteine cathepsins: regulators of antitumour immune response. Expert Opin. Biol. Ther. 6: 1295-1309 (2006).
Obregon C, Rothen-Rutishauser B, Gerber P, Gehr P, Nicod LP. Active uptake of dendritic cell-derived exovesicles by epithelial cells induces the release of inflammatory mediators through a TNF-alpha-mediated pathway. Am. J. Pathol. 175: 696-705 (2009). *
Odunsi K, Lele S, Savalgi R. Vaccine therapy for cancer: fact or fiction? Surg. Technol. Int. 13: 39-47 (2004).
Oelert T, Reibke R, Limmer A, Knolle P, Hammerling GJ, Arnold B. Regulation of autoimmunity - lessons from liver and skin. Falk Symposium 142: GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), October 12 - 13, 2004, p. 27 (2004). *
Oelke M, Schneck JP. Overview of a HLA-Ig based "Lego-like system" for T cell monitoring, modulation and expansion. Immunol. Res. Jan 20 [Epub ahead of print] (2010). *
Offner H, Sinha S, Wang C, Burrows GG, Vandenbark AA. Recombinant T cell receptor ligands: immunomodulatory, neuroprotective and neuroregenerative effects suggest application as therapy for multiple sclerosis. Rev. Neurosci. 19: 327-339 (2008).
Ogawa N, Shimoyama K, Kawanami T. Molecular mechanisms of salivary gland destruction in patients with Sjogren's syndrome. Nihon Rinsho Meneki Gakkai Kaishi 28: 10-20 (2005).
Oh BC, Lee HM, Lim DP, Cho JJ, Lee G, Lee DS, Lee JR. Effect of immature dendritic cell injection before heterotropic cardiac allograft. Transplant. Proc. 38: 3189-3192 (2006). *
Ohashi T, Nagai M, Okada H, Takayanagi R, Shida H. Activation and detection of HTLV-I Tax-specific CTLs by epitope expressing single-chain trimers of MHC class I in a rat model. Retrovirology 5: 90 (2008).
Ohmura-Hoshino M, Matsuki Y, Mito-Yoshida M, Goto E, Aoki-Kawasumi M, Nakayama M, Ohara O, Ishido S. Cutting edge: requirement of MARCH-I-mediated MHC II ubiquitination for the maintenance of conventional dendritic cells. J. Immunol. 183: 6893-6897 (2009).
Ohsawa M. Heavy metal-induced immunotoxicity and its mechanisms. Yakugaku Zasshi 129: 305-319 (2009).
Ojcius DM, Delarbre C, Kourilsky P, Gachelin G. MHC and MHC-related proteins as pleiotropic signal molecules. FASEB J. 16: 202-206 (2002). *
Okamoto J, Onda M, Hirata T, Miyamoto S, Akaishi J, Mikami I, Hirai K, Haraguchi S, Koizumi K, Shimizu K. Dissimilarity in gene expression profiles of lung adenocarcinoma in Japanese men and women. Gend. Med. 3: 223-235 (2006).
Okamoto K, Makino S, Yoshikawa Y, Takaki A, Nagatsuka Y, Ota M, Tamiya G, Kimura A, Bahram S, Inoko H. Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis. Am. J. Hum. Genet. 72: 303-312 (2003). *
Okamoto M, Furuichi S, Nishioka Y, Oshikawa T, Tano T, Ahmed SU, Takeda K, Akira S, Ryoma Y, Moriya Y, Saito M, Sone S, Sato M. Expression of Toll-like receptor 4 on dendritic cells is significant for anticancer effect of dendritic cell-based immunotherapy in combination with an active component of OK-432, a Streptococcal preparation. Cancer Res. 64: 5461-5670 (2004). *
Okano M, Sugata Y, Fujiwara T, Matsumoto R, Nishibori M, Shimizu K, Maeda M, Kimura Y, Kariya S, Hattori H, Yokoyama M, Kino K, Nishizaki K. E prostanoid 2 (EP2)/EP4-mediated suppression of antigen-specific human T-cell responses by prostaglandin E. Immunology 118: 343-352 (2006). *
Ola TO, Williams NA. Protection of non-obese diabetic mice from autoimmune diabetes by Escherichia coli heat-labile enterotoxin B subunit. Immunology 117: 262-270 (2006). *
Oldstone MB. Molecular and cellular mechanisms, pathogenesis, and treatment of insulin-dependent diabetes obtained through study of a transgenic model of molecular mimicry. Curr. Top. Microbiol. Immunol. 296: 65-87 (2005).
Oldstone MB, von Herrath M. Virus-induced autoimmune disease: transgenic approach to mimic insulin-dependent diabetes mellitus and other autoimmune diseases. APMIS 104: 689-697 (1996).
Oliveira LA, Ribas F, Bicalho MG, Tsuneto LT, Petzl-Erler ML. High frequencies of alleles MICA*020 and MICA*027 in Amerindians and evidence of positive selection on exon 3. Genes Immun. 9: 697-705 (2008). *
Olleros ML, Vesin D, Martinez-Soria E, Allenbach C, Tacchini-Cottier F, Pache JC, Marchal G, Rahman J, Fernandez C, Izui S, Garcia I. Interleukin-12p40 overexpression promotes interleukin-12p70 and interleukin-23 formation but does not affect bacille Calmette-Guerin and Mycobacterium tuberculosis clearance. Immunology 122: 350-361 (2007). *
Ollier WE, Kennedy LJ, Thomson W, Barnes AN, Bell SC, Bennett D, Angles JM, Innes JF, Carter SD. Dog MHC alleles containing the human RA shared epitope confer susceptibility to canine rheumatoid arthritis. Immunogenetics 53: 669-673 (2001).
Olofsson PS, Soderstrom LA, Wagsater D, Sheikine Y, Ocaya P, Lang F, Rabu C, Chen L, Rudling M, Aukrust P, Hedin U, Paulsson-Berne G, Sirsjo A, Hansson GK. CD137 is expressed in human atherosclerosis and promotes development of plaque inflammation in hypercholesterolemic mice. Circulation 117: 1292-1301 (2008). *
Olson JK, Ercolini AM, Miller SD. A virus-induced molecular mimicry model of multiple sclerosis. Curr. Top. Microbiol. Immunol. 296: 39-53 (2005).
Olson R, Dulac C, Bjorkman PJ. MHC homologs in the nervous system - they haven't lost their groove. Curr. Opin. Neurobiol. 16: 351-357 (2006).
Olsson T, Jagodic M, Piehl F, Wallstrom E. Genetics of autoimmune neuroinflammation. Curr. Opin. Immunol. 18: 643-649 (2006).
Onishi S, Sakamaki T, Maeda T, Iwamura S, Tomita A, Saibara T, Yamamoto Y. DNA typing of HLA class II genes; DRB1*0803 increases the susceptibility of Japanese to primary biliary cirrhosis. J. Hepatol. 21: 1053-1060 (1994).
Onishi Y, Fehervari Z, Yamaguchi T, Sakaguchi S. Foxp3+ natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation. Proc. Natl. Acad. Sci. U.S.A. 105: 10113-10118 (2008). *
Orchard TR, Dhar A, Simmons JD, Vaughan R, Welsh KI, Jewell DP. MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathy. Clin. Exp. Immunol. 126: 437-440 (2001). *
Oreshkova T, Wang H, Seier AM, Sindrilaru A, Varga G, Grabbe S, Scharffetter-Kochanek K, Peters T. Beta(2) integrin deficiency yields unconventional double-negative T cells distinct from mature classical natural killer T cells in mice. Immunology 128: 271-286 (2009). *
Orozco G, Robledo G, Linga-Reddy MV, Garcia A, Pascual-Salcedo D, Balsa A, Gonzalez-Gay MA, Eimon A, Paira S, Scherbarth HR, Pons-Estel BA, Petersson IF, Alarcon-Riquelme M, Martin J. Study of the role of a functional polymorphism of MHC2TA in rheumatoid arthritis in three ethnically different populations. Rheumatology (Oxford) 45: 1442-1444 (2006). *
Orr MK, Burnside JS, Phillips CA, Philip R, Dombrowski KE, Wright SE. MHC-restricted presentation of a single repeat of MUC1 mucin. Immunol. Invest. 36: 271-283 (2007). *
Ortega-Gutierrez S, Molina-Holgado E, Arevalo-Martin A, Correa F, Viso A, Lopez-Rodriguez ML, Di Marzo V, Guaza C. Activation of the endocannabinoid system as a therapeutic approach in a murine model of multiple sclerosis. FASEB J. 19: 1338-1340 (2005). *
Orth T, Neurath M, Schirmacher P, Galle PR, Mayet WJ. A novel rat model of chronic fibrosing cholangitis induced by local administration of a hapten reagent into the dilated bile duct is associated with increased TNF-alpha production and autoantibodies. J. Hepatol. 33: 862-872 (2000). *
Oshima M, Deitiker P, Atassi M. Targeting the antigen-binding site of HLA-restricting alleles in treatment of autoimmune disease. Crit. Rev. Immunol. 27: 271-288 (2007).
Oshima M, Ohtani M, Deitiker PR, Glenn Smith R, Mosier DR, Zouhair Atassi M. Suppression by mAbs against DQB1 peptides of in vitro proliferation of AChR-specific T cells from myasthenia gravis patients. Autoimmunity 38: 161-169 (2005).
Oshitani N, Hato F, Jinno Y, Sawa Y, Hara J, Nakamura S, Matsumoto T, Arakawa T, Kitano A, Kitagawa S, Kuroki T. Heterogeneity of HPLC profiles of human class II MHC-bound peptides isolated from intestine with inflammatory bowel disease. Dig. Dis. Sci. 47: 2088-2094 (2002). *
Oshitani N, Hato F, Kitagawa S, Maeda K, Higuchi K, Matsumoto T, Arakawa T. Analysis of intestinal HLA-DR bound peptides and dysregulated immune responses to enteric flora in the pathogenesis of inflammatory bowel disease. Int. J. Mol. Med. 11: 99-104 (2003). *
Osna NA, White RL, Thiele GM, Donohue TM Jr. Ethanol metabolism alters major histocompatibility complex class I-restricted antigen presentation in liver cells. Hepatology 49: 1308-1315 (2009).
Ossevoort M, Zaldumbide A, Cramer SJ, van der Voort EI, Toes RE, Hoeben RC. Characterization of an immuno 'stealth' derivative of the herpes simplex virus thymidine-kinase gene. Cancer Gene Ther. 13: 584-591 (2006).
Ostankovitch M, Altrich-Vanlith M, Robila V, Engelhard VH. N-Glycosylation enhances presentation of a MHC class I-restricted epitope from tyrosinase. J. Immunol. 182: 4830-4835 (2009).
Osterhues A, Liebmann S, Schmid M, Buk D, Huss R, Graeve L, Zeindl-Eberhart E. Stem cells and experimental leukemia can be distinguished by lipid raft protein composition. Stem Cells Dev. 15: 677-686 (2006).
Osterloh A, Breloer M. Heat shock proteins: linking danger and pathogen recognition. Med. Microbiol. Immunol. 197: 1-8 (2008). *
Osterloh P, Linkemann K, Tenzer S, Rammensee HG, Radsak MP, Busch DH, Schild H. Proteasomes shape the repertoire of T cells participating in antigen-specific immune responses. Proc. Natl. Acad. Sci. U.S.A. 103: 5042-5047 (2006). *
Ostrov DA, Barnes CL, Smith LE, Binns S, Brusko TM, Brown AC, Quint PS, Litherland SA, Roopenian DC, Iczkowski KA. Characterization of HKE2: an ancient antigen encoded in the major histocompatibility complex. Tissue Antigens 69: 181-188 (2007). *
Ostrowski M, Izdebska M, Grzanka A, Zuryn A, Grzanka D. The involvement of transglutaminase 2 in autoimmunological diseases. Postepy. Hig. Med. Dosw. (Online) 59: 334-339 (2005).
Oswald-Richter K, Sato H, Hajizadeh R, Shepherd BE, Sidney J, Sette A, Newman LS, Drake WP. Mycobacterial ESAT-6 and katG are recognized by sarcoidosis CD4+ T cells when presented by the American sarcoidosis susceptibility allele, DRB1*1101. J. Clin. Immunol. Jun 18 [Epub ahead of print] (2009). *
Ota M, Katsuyama Y, Hamano H, Umemura T, Kimura A, Yoshizawa K, Kiyosawa K, Fukushima H, Bahram S, Inoko H, Kawa S. Two critical genes (HLA-DRB1 and ABCF1) in the HLA region are associated with the susceptibility to autoimmune pancreatitis. Immunogenetics 59: 45-52 (2007). *
Ota M, Katsuyama Y, Kimura A, Tsuchiya K, Kondo M, Naruse T, Mizuki N, Itoh K, Sasazuki T, Inoko H. A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region. Genomics 71: 263-270 (2001). *
Ottaviani C, Nasorri F, Bedini C, de Pita O, Girolomoni G, Cavani A. CD56(bright)CD16(-) NK cells accumulate in psoriatic skin in response to CXCL10 and CCL5 and exacerbate skin inflammation. Eur. J. Immunol. 36: 118-128 (2006). *
Otten LA, Tacchini-Cottier F, Lohoff M, Annunziato F, Cosmi L, Scarpellino L, Louis J, Steimle V, Reith W, Acha-Orbea H. Deregulated MHC class II transactivator expression leads to a strong Th2 bias in CD4+ T lymphocytes. J. Immunol. 170: 1150-1157 (2003). *
Otting N, de Vos-Rouweler AJ, Heijmans CM, de Groot NG, Doxiadis GG, Bontrop RE. MHC class I A region diversity and polymorphism in macaque species. Immunogenetics 59: 367-375 (2007). *
Otto JM, Chandrasekeran R, Vermes C, Mikecz K, Finnegan A, Rickert SE, Enders JT, Glant TT. A genome scan using a novel genetic cross identifies new susceptibility loci and traits in a mouse model of rheumatoid arthritis. J. Immunol. 165: 5278-5286 (2000). *
Otto JM, Cs-Szabo G, Gallagher J, Velins S, Mikecz K, Buzas EI, Enders JT, Li Y, Olsen BR, Glant TT. Identification of multiple loci linked to inflammation and autoantibody production by a genome scan of a murine model of rheumatoid arthritis. Arthritis Rheum. 42: 2524-2531 (1999). *
Oukka M. Interplay between pathogenic Th17 and regulatory T cells. Ann. Rheum. Dis. 66 Suppl. 3: iii87-iii90 (2007).
Ouyang GF, Saio M, Suwa T, Imai H, Nakagawa J, Nonaka K, Umemura N, Kijima M, Takami T. Interleukin-2 augmented activation of tumor associated macrophage plays the main role in MHC class I in vivo induction in tumor cells that are MHC negative in vitro. Int. J. Oncol. 28: 1201-1208 (2006). *
Overstreet MG, Freyberger H, Cockburn IA, Chen YC, Tse SW, Zavala F. CpG-enhanced CD8+ T cell responses to peptide immunization are severely inhibited by B cells. Eur. J. Immunol. Oct 14 [Epub ahead of print] (2009). *
Ozaki H, Kinoshita K, Hori M. Mechanism of the intestinal dysmotility in the inflammatory bowel diseases: possible involvement of muscularis resident macrophages. Nippon Yakurigaku Zasshi 122: 46P-50P (2003).
Ozawa M, Terasaki PI, Lee JH, Castro R, Alberu J, Alonso C, Alvarez I, Toledo R, Alvez H, Monterio M, Teixeira J, Campbell P, Ciszek M, Charron D, Gautreau C, Christiansen F, Conca R, Gomez B, Monteon F, Grosse-Wilde H, Heinemann F, Humar I, et al. 14th International HLA and Immunogenetics Workshop: report on the prospective chronic rejection project. Tissue Antigens 69 Suppl. 1: 174-179 (2007). *
P PK, Bischof O, Purbey PK, Notani D, Urlaub H, Dejean A, Galande S. Functional interaction between PML and SATB1 regulates chromatin-loop architecture and transcription of the MHC class I locus. Nat. Cell Biol. 9: 45-56 (2007). *
Pacholczyk R, Kern J, Singh N, Iwashima M, Kraj P, Ignatowicz L. Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells. Immunity 27: 493-504 (2007). *
Padigel UM, Lee JJ, Nolan TJ, Schad GA, Abraham D. Eosinophils can function as antigen-presenting cells to induce primary and secondary immune responses to Strongyloides stercoralis. Infect. Immun. 74: 3232-3238 (2006). *
Pageaux GP, Blanc P, Perrigault PF, Navarro F, Fabre JM, Souche B, Domergue J, Larrey D, Michel H. Failure of ursodeoxycholic acid to prevent acute cellular rejection after liver transplantation. J. Hepatol. 23: 119-122 (1995). *
Painter CA, Cruz A, Lopez GE, Stern LJ, Zavala-Ruiz Z. Model for the peptide-free conformation of class II MHC proteins. PLoS ONE 3: e2403 (2008). *
Pais TF, Figueiredo C, Peixoto R, Braz MH, Chatterjee S. Necrotic neurons enhance microglial neurotoxicity through induction of glutaminase by a MyD88-dependent pathway. J. Neuroinflammation 5: 43 (2008).
Pajtasz-Piasecka E, Rossowska J, Szyda A, Krawczenko A, Dus D. Generation of anti-tumor response by JAWS II mouse dendritic cells transduced with murine interleukin 12 genes. Oncol. Rep. 17: 1249-1257 (2007). *
Palaga T, Buranaruk C, Rengpipat S, Fauq AH, Golde TE, Kaufmann SH, Osborne BA. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Eur. J. Immunol. 38: 174-183 (2008). *
Palikhe A, Lokki ML, Pussinen PJ, Paju S, Ahlberg J, Asikainen S, Seppanen M, Valtonen V, Nieminen MS, Sinisalo J. Lymphotoxin alpha LTA+496C allele is a risk factor for periodontitis in patients with coronary artery disease. Tissue Antigens 71: 530-537 (2008). *
Palikhe A, Lokki ML, Saikku P, Leinonen M, Paldanius M, Sepp�nen M, Valtonen V, Nieminen MS, Sinisalo J. Chlamydia pneumoniae infection is associated with HLA-B*35 in patients with coronary artery disease. Clin. Vaccine Immunol. 15: 55-59 (2008). *
Palikhe A, Sinisalo J, Seppanen M, Valtonen V, Nieminen MS, Lokki ML. Human MHC region harbors both susceptibility and protective haplotypes for coronary artery disease. Tissue Antigens 69: 47-55 (2007). *
Palmer DC, Chan CC, Gattinoni L, Wrzesinski C, Paulos CM, Hinrichs CS, Powell DJ Jr, Klebanoff CA, Finkelstein SE, Fariss RN, Yu Z, Nussenblatt RB, Rosenberg SA, Restifo NP. Effective tumor treatment targeting a melanoma/melanocyte-associated antigen triggers severe ocular autoimmunity. Proc. Natl. Acad. Sci. U.S.A. 105: 8061-8066 (2008). *
Palmer E, Naeher D. Affinity threshold for thymic selection through a T-cell receptor-co-receptor zipper. Nat. Rev. Immunol. 9: 207-213 (2009). *
Palmer JM, Diamond AG, Yeaman SJ, Bassendine MF, Jones DE. T cell responses to the putative dominant autoepitope in primary biliary cirrhosis (PBC). Clin. Exp. Immunol. 116: 133-139 (1999). *
Palmer JM, Robe AJ, Burt AD, Kirby JA, Jones DE. Covalent modification as a mechanism for the breakdown of immune tolerance to pyruvate dehydrogenase complex in the mouse. Hepatology 39: 1583-1592 (2004). *
Paludan C, Schmid D, Landthaler M, Vockerodt M, Kube D, Tuschl T, Munz C. Endogenous MHC class II processing of a viral nuclear antigen after autophagy. Science 307: 593-596 (2005). *
Panasiuk A, Prokopowicz D, Zak J. Peripheral blood T, B lymphocytes and NK cells in primary biliary cirrhosis. Rocz. Akad. Med. Bialymst. 46: 231-239 (2001).
Pando M, Larriba J, Fernandez GC, Fainboim H, Ciocca M, Ramonet M, Badia I, Daruich J, Findor J, Tanno H, Canero-Velasco C, Fainboim L. Pediatric and adult forms of type I autoimmune hepatitis in Argentina: evidence for differential genetic predisposition. Hepatology 30: 1374-1380 (1999). *
Pang B, Neijssen J, Qiao X, Janssen L, Janssen H, Lippuner C, Neefjes J. Direct antigen presentation and gap junction mediated cross-presentation during apoptosis. J. Immunol. 183: 1083-1090 (2009).
Pang L, Wang L, Suo T, Hao H, Fang X, Jia J, Huang F, Tang J. Tumor necrosis factor-alpha blockade leads to decreased peripheral T cell reactivity and increased dendritic cell number in peripheral blood of patients with ankylosing spondylitis. J. Rheumatol. 35: 2220-2228 (2008).
Pani MA, Wood JP, Bieda K, Toenjes RR, Usadel KH, Badenhoop K. The variable endogenous retroviral insertion in the human complement C4 gene: a transmission study in type I diabetes mellitus. Hum. Immunol. 63: 481-484 (2002).
Panigrahi A, Siddiqui JA, Rai A, Margoob A, Khaira A, Bhowmik D, Tiwari SC, Guleria S, Mehra NK. Allosensitization to HLA and MICA is an important measure of renal graft outcome. Clin. Transpl. 2007: 211-217 (2007).
Pantopoulos K. Function of the hemochromatosis protein HFE: lessons from animal models. World J. Gastroenterol. 14: 6893-6901 (2008). *
Papassavas EC, Spyropoulou-Vlachou M, Papassavas AC, Schipper RF, Doxiadis IN, Stavropoulos-Giokas C. MHC class I and class II phenotype, gene, and haplotype frequencies in Greeks using molecular typing data. Hum. Immunol. 61: 615-623 (2000).
Papenfuss TL, Kithcart AP, Powell ND, McClain MA, Gienapp IE, Shawler TM, Whitacre CC. Disease-modifying capability of murine Flt3-ligand DCs in experimental autoimmune encephalomyelitis. J. Leukoc. Biol. 82: 1510-1518 (2007). *
Papiha SS, Murty GE, Ad'Hia A, Mains BT, Venning M. Association of Wegener's granulomatosis with HLA antigens and other genetic markers. Ann. Rheum. Dis. 51: 246-248 (1992). *
Parachikova A, Agadjanyan MG, Cribbs DH, Blurton-Jones M, Perreau V, Rogers J, Beach TG, Cotman CW. Inflammatory changes parallel the early stages of Alzheimer disease. Neurobiol. Aging 28: 1821-1833 (2007).
Parekh VV, Lalani S, Van Kaer L. The in vivo response of invariant natural killer T cells to glycolipid antigens. Int. Rev. Immunol. 26: 31-48 (2007).
Parga-Lozano C, Reguera R, Gomez-Prieto P, Arnaiz-Villena A. Evolution of MHC-G, MHC-C and NK KIR receptors in primates. Hum. Immunol. 70: 1035-1040 (2009).
Parham P. Presentation of HLA class I-derived peptides: potential involvement in allorecognition and HLA-B27-associated arthritis. Immunol. Rev. 154: 137-154 (1996).
Parham P. Taking license with natural killer cell maturation and repertoire development. Immunol. Rev. 214: 155-160 (2006). *
Parham P. MHC class I molecules and KIRS in human history, health and survival. Nat. Rev. Immunol. 5: 201-214 (2005). *
Parham P. Immunogenetics of killer cell immunoglobulin-like receptors. Mol. Immunol. 42: 459-462 (2005). *
Parikh-Patel A, Gold E, Mackay IR, Gershwin ME. The geoepidemiology of primary biliary cirrhosis: contrasts and comparisons with the spectrum of autoimmune diseases. Clin. Immunol. 91: 206-218 (1999). *
Park M, Kim DJ, Kim KJ, Hong CB, Kim YJ, Cheong HS, Shin HD, Lee EJ, Kim HN, Chung HW, Kim EK, Lee JY, Kim HL. Genetic associations of common deletion polymorphisms in families with Avellino corneal dystrophy. Biochem. Biophys. Res. Commun. 387: 688-693 (2009). *
Park SH, Park KS, Seo YI, Min DJ, Kim WU, Kim TG, Cho CS, Mok JW, Park KS, Kim HY. Association of MICA polymorphism with HLA-B51 and disease severity in Korean patients with Behcet's disease. J. Korean Med. Sci. 17: 366-370 (2002). *
Park SY, Kim Y. Surfactin inhibits immunostimulatory function of macrophages through blocking NK-kappaB, MAPK and Akt pathway. Int. Immunopharmacol. 9: 886-893 (2009).
Park Y, Eisenbarth GS. Genetic susceptibility factors of type 1 diabetes in Asians. Diabetes Metab. Res. Rev. 17: 2-11 (2001).
Park Y, Lee H, Sanjeevi CB, Eisenbarth GS. MICA polymorphism is associated with type 1 diabetes in the Korean population. Diabetes Care 24: 33-38 (2001). *
Park YS, Sanjeevi CB, Robles D, Yu L, Rewers M, Gottlieb PA, Fain P, Eisenbarth GS. Additional association of intra-MHC genes, MICA and D6S273, with Addison's disease. Tissue Antigens 60: 155-163 (2002). *
Parkes AB, Darke C, Othman S, Thomas M, Young N, Richards CJ, Hall R, Lazarus JH. Major histocompatibility complex class II and complement polymorphisms in postpartum thyroiditis. Eur. J. Endocrinol. 134: 449-453 (1996).
Parkkila S, Niemela O, Britton RS, Fleming RE, Waheed A, Bacon BR, Sly WS. Molecular aspects of iron absorption and HFE expression. Gastroenterology 121: 1489-1496 (2001). *
Parmar S, de Lima M, Zou Y, Patah P, Liu P, Cano P, Rondon G, Pesoa S, de Padua Silva L, Qazilbash MH, Hosing C, Popat U, Kebriaei P, Shpall EJ, Giralt S, Champlin RE, Stastny P, Fernandez-Vina M. Donor-recipient mismatches in MHC class I chain-related gene A in unrelated donor transplantation lead to increased incidence of acute graft-versus-host disease. Blood 114: 2884-2887 (2009). *
Parry CS, Brooks BR. A new model defines the minimal set of polymorphism in HLA-DQ and -DR that determines susceptibility and resistance to autoimmune diabetes. Biol. Direct 3: 42 (2008). *
Partanen J, Milner C, Campbell RD, Maki M, Lipsanen V, Koskimies S. HLA-linked heat-shock protein 70 (HSP70-2) gene polymorphism and celiac disease. Tissue Antigens 41: 15-19 (1993).
Partanen J, Peterson P, Westman P, Aranko S, Krohn K. Major histocompatibility complex class II and III in Addison's disease. MHC alleles do not predict autoantibody specificity and 21-hydroxylase gene polymorphism has no independent role in disease susceptibility. Hum. Immunol. 41: 135-140 (1994).
Pascal V, Stulberg MJ, Anderson SK. Regulation of class I major histocompatibility complex receptor expression in natural killer cells: one promoter is not enough! Immunol. Rev. 214: 9-21 (2006). *
Pascolo S, Ginhoux F, Laham N, Walter S, Schoor O, Probst J, Rohrlich P, Obermayr F, Fisch P, Danos O, Ehrlich R, Lemonnier FA, Rammensee HG. The non-classical HLA class I molecule HFE does not influence the NK-like activity contained in fresh human PBMCs and does not interact with NK cells. Int. Immunol. 17: 117-122 (2005). *
Pascual M, Mataran L, Jones G, Shing D, van der Slik AR, Giphart MJ, Schreuder GM, de Vries RR, Breedveld FC, Roovers E, Zanelli E, Martin J. HLA haplotypes and susceptibility to rheumatoid arthritis. More than class II genes. Scand. J. Rheumatol. 31: 275-278 (2002). *
Pasquier B, Lepelletier Y, Baude C, Hermine O, Monteiro RC. Differential expression and function of IgA receptors (CD89 and CD71) during maturation of dendritic cells. J. Leukoc. Biol. 76: 1134-1141 (2004). *
Patarroyo JC, Stuve O, Piskurich JF, Hauser SL, Oksenberg JR, Zamvil SS. Single nucleotide polymorphisms in MHC2TA, the gene encoding the MHC class II transactivator (CIITA). Genes Immun. 3: 34-37 (2002). *
Patel SR, Cadwell CM, Medford A, Zimring JC. Transfusion of minor histocompatibility antigen-mismatched platelets induces rejection of bone marrow transplants in mice. J. Clin. Invest. 119: 2787-2794 (2009). *
Pathan S, Gowdy RE, Cooney R, Beckly JB, Hancock L, Guo C, Barrett JC, Morris A, Jewell DP. Confirmation of the novel association at the BTNL2 locus with ulcerative colitis. Tissue Antigens 74: 322-329 (2009). *
Patino-Lopez G, Hevezi P, Lee J, Willhite D, Verge GM, Lechner SM, Ortiz-Navarrete V, Zlotnik A. Human class-I restricted T cell associated molecule is highly expressed in the cerebellum and is a marker for activated NKT and CD8(+) T lymphocytes. J. Neuroimmunol. 171: 145-155 (2006).
Paus R, Christoph T, Muller-Rover S. Immunology of the hair follicle: a short journey into terra incognita. J. Investig. Dermatol. Symp. Proc. 4: 226-234 (1999). *
Paus R, Ito N, Takigawa M, Ito T. The hair follicle and immune privilege. J. Investig. Dermatol. Symp. Proc. 8: 188-194 (2003). *
Paus R, Nickoloff BJ, Ito T. A 'hairy' privilege. Trends Immunol. 26: 32-40 (2005). *
Paust S, Cantor H. Regulatory T cells and autoimmune disease. Immunol. Rev. 204: 195-207 (2005). *
Pay S, Simsek I, Erdem H, Dinc A. Immunopathogenesis of Behcet's disease with special emphasize on the possible role of antigen presenting cells. Rheumatol. Int. 27: 417-424 (2007). *
Peaper DR, Wearsch PA, Cresswell P. Tapasin and ERp57 form a stable disulfide-linked dimer within the MHC class I peptide-loading complex. EMBO J. 24: 3613-3623 (2005). *
Pearce SH, Merriman TR. Genetic progress towards the molecular basis of autoimmunity. Trends Mol. Med. 12: 90-98 (2006). *
Pedersen CD, Fang JJ, Pedersen AE. A comparative study of transfection methods for RNA interference in bone marrow-derived murine dendritic cells. Scand. J. Immunol. 70: 447-456 (2009). *
Peelman LJ, Chardon P, Nunes M, Renard C, Geffrotin C, Vaiman M, Van Zeveren A, Coppieters W, van de Weghe A, Bouquet Y, et al. The BAT1 gene in the MHC encodes an evolutionarily conserved putative nuclear RNA helicase of the DEAD family. Genomics 26: 210-218 (1995).
Peelman LJ, Chardon P, Vaiman M, Mattheeuws M, Van Zeveren A, Van de Weghe A, Bouquet Y, Campbell RD. A detailed physical map of the porcine major histocompatibility complex (MHC) class III region: comparison with human and mouse MHC class III regions. Mamm. Genome 7: 363-367 (1996). *
Peh CA, Burrows SR, Barnden M, Khanna R, Cresswell P, Moss DJ, McCluskey J. HLA-B27-restricted antigen presentation in the absence of tapasin reveals polymorphism in mechanisms of HLA class I peptide loading. Immunity 8: 531-542 (1998). *
Pena AS. Contribution of genetics to a new vision in the understanding of inflammatory bowel disease. World J. Gastroenterol. 12: 4784-4787 (2006). *
Pena-Cruz V, Ito S, Dascher CC, Brenner MB, Sugita M. Epidermal Langerhans cells efficiently mediate CD1a-dependent presentation of microbial lipid antigens to T cells. J. Invest. Dermatol. 121: 517-521 (2003). *
Penaloza-MacMaster P, Masopust D, Ahmed R. T-cell reconstitution without T-cell immunopathology in two models of T-cell-mediated tissue destruction. Immunology 128: 164-171 (2009). *
Pene F, Courtine E, Ouaaz F, Zuber B, Sauneuf B, Sirgo G, Rousseau C, Toubiana J, Balloy V, Chignard M, Mira JP, Chiche JD. TLR2 and TLR4 contribute to sepsis-induced depletion of spleen dendritic cells. Infect. Immun. 77: 5651-5658 (2009). *
Peng J, Liu C, Zhu K, Zhu Y, Yu Y, Li J, Hou M, Chen X, Xu C, Zhang M. The TNF2 allele is a risk factor to severe aplastic anemia independent of HLA-DR. Hum. Immunol. 64: 896-901 (2003).
Peng Q, Li K, Wang N, Li Q, Asgari E, Lu B, Woodruff TM, Sacks SH, Zhou W. Dendritic cell function in allostimulation is modulated by C5aR signaling. J. Immunol. 183: 6058-6068 (2009).
Peng Y, Lin FC, Verardi PH, Jones LA, McChesney MB, Yilma TD. Pseudotyped single-cycle SIVs expressing gamma interferon augment T cell priming responses in vitro. J. Virol. 81: 2187-2195 (2007). *
Penna G, Fibbi B, Amuchastegui S, Cossetti C, Aquilano F, Laverny G, Gacci M, Crescioli C, Maggi M, Adorini L. Human benign prostatic hyperplasia stromal cells as inducers and targets of chronic immuno-mediated inflammation. J. Immunol. 182: 4056-4064 (2009).
Penttinen MA, Ekman P, Granfors K. Non-antigen presenting effects of HLA-B27. Curr. Mol. Med. 4: 41-49 (2004).
Penzotti JE, Nepom GT, Lybrand TP. Use of T cell receptor/HLA-DRB1*04 molecular modeling to predict site-specific interactions for the DR shared epitope associated with rheumatoid arthritis. Arthritis Rheum. 40: 1316-1326 (1997).
Pepper M, Linehan JL, Pagan AJ, Zell T, Dileepan T, Cleary PP, Jenkins MK. Different routes of bacterial infection induce long-lived T(H)1 memory cells and short-lived T(H)17 cells. Nat. Immunol. 11: 83-90 (2010). *
Perchellet A, Brabb T, Goverman JM. Crosspresentation by nonhematopoietic and direct presentation by hematopoietic cells induce central tolerance to myelin basic protein. Proc. Natl. Acad. Sci. U.S.A. 105: 14040-14045 (2008). *
Perdriger A, Chales G, Semana G, Guggenbuhl P, Meyer O, Quillivic F, Pawlotsky Y. Role of HLA-DR-DR and DR-DQ associations in the expression of extraarticular manifestations and rheumatoid factor in rheumatoid arthritis. J. Rheumatol. 24: 1272-1276 (1997).
Perdriger A, Guggenbuhl P, Chales G, Yaouanq J, Quelvennec E, Bonnard MN, Pawlotsky Y, Semana G. Positive association of the HLA DMB1*0101-0101 genotype with rheumatoid arthritis. Rheumatology (Oxford) 38: 448-452 (1999). *
Perera L, Shao L, Patel A, Evans K, Meresse B, Blumberg R, Geraghty D, Groh V, Spies T, Jabri B, Mayer L. Expression of nonclassical class I molecules by intestinal epithelial cells. Inflamm. Bowel Dis. 13: 298-307 (2007). *
Pericak-Vance MA, Rimmler JB, Martin ER, Haines JL, Garcia ME, Oksenberg JR, Barcellos LF, Lincoln R, Goodkin DE, Hauser SL. Linkage and association analysis of chromosome 19q13 in multiple sclerosis. Neurogenetics 3: 195-201 (2001). *
Perona-Wright G, Anderton SM, Howie SE, Gray D. IL-10 permits transient activation of dendritic cells to tolerize T cells and protect from central nervous system autoimmune disease. Int. Immunol. 19: 1123-1134 (2007). *
Perria CL, Rajamanickam V, Lapinksi PE, Raghavan M. Catalytic site modifications of TAP1 and TAP2 and their functional consequences. J. Biol. Chem. 281: 39839-39851 (2006). *
Perrigoue JG, Saenz SA, Siracusa MC, Allenspach EJ, Taylor BC, Giacomin PR, Nair MG, Du Y, Zaph C, van Rooijen N, Comeau MR, Pearce EJ, Laufer TM, Artis D. MHC class II-dependent basophil-CD4(+) T cell interactions promote T(H)2 cytokine-dependent immunity. Nat. Immunol. 10: 697-705 (2009). *
Peru H, Soylemezoglu O, Gonen S, Cetinyurek A, Bakkaloglu SA, Buyan N, Hasanoglu E. HLA class 1 associations in Henoch Schonlein purpura: increased and decreased frequencies. Clin. Rheumatol. 27: 5-10 (2008). *
Peter M, Bode K, Lipford GB, Eberle F, Heeg K, Dalpke AH. Characterization of suppressive oligodeoxynucleotides that inhibit Toll-like receptor-9-mediated activation of innate immunity. Immunology 123: 118-128 (2008). *
Peters B, Bui HH, Frankild S, Nielson M, Lundegaard C, Kostem E, Basch D, Lamberth K, Harndahl M, Fleri W, Wilson SS, Sidney J, Lund O, Buus S, Sette A. A community resource benchmarking predictions of peptide binding to MHC-I molecules. PLoS Comput. Biol. 2: e65 (2006). *
Peters B, Sidney J, Bourne P, Bui HH, Buus S, Doh G, Fleri W, Kronenberg M, Kubo R, Lund O, Nemazee D, Ponomarenko JV, Sathiamurthy M, Schoenberger SP, Stewart S, Surko P, Way S, Wilson S, Sette A. The design and implementation of the immune epitope database and analysis resource. Immunogenetics 57: 326-336 (2005). *
Petersdorf EW, Hansen JA. New advances in hematopoietic cell transplantation. Curr. Opin. Hematol. 15: 549-554 (2008).
Petersdorf EW, Malkki M, Gooley TA, Martin PJ, Guo Z. MHC haplotype matching for unrelated hematopoietic cell transplantation. PLoS Med. 4: e8 (2007). *
Petersen J, Purcell AW, Rossjohn J. Post-translationally modified T cell epitopes: immune recognition and immunotherapy. J. Mol. Med. Sep 8 [Epub ahead of print] (2009). *
Peterson P, Uibo R, Krohn KJ. Adrenal autoimmunity: results and developments. Trends Endocrinol. Metab. 11: 285-290 (2000). *
Petersson K, Forsberg G, Walse B. Interplay between superantigens and immunoreceptors. Scand. J. Immunol. 59: 345-355 (2004). *
Petkova SB, Akilesh S, Sproule TJ, Christianson GJ, Al Khabbaz H, Brown AC, Presta LG, Meng YG, Roopenian DC. Enhanced half-life of genetically engineered human IgG1 antibodies in a humanized FcRn mouse model: potential application in humorally mediated autoimmune disease. Int. Immunol. 18: 1759-1769 (2006). *
Petzmann S, Maercker C, Markert E, Kern I, Osolnik K, Pohl W, Popper HH. Enhanced proliferation and decreased apoptosis in lung lavage cells of sarcoidosis patients. Sarcoidosis Vasc. Diffuse Lung Dis. 23: 190-200 (2006).
Pfender NA, Grosch S, Roussel G, Koch M, Trifilieff E, Greer JM. Route of uptake of palmitoylated encephalitogenic peptides of myelin proteolipid protein by antigen-presenting cells: importance of the type of bond between lipid chain and peptide and relevance to autoimmunity. J. Immunol. 180: 1398-1404 (2008). *
Piao WH, Song XG, Liu MC, He Y, Zhang HH, Xu WX, Li ZL, Zhang HQ, Ling SG, Wang GQ. Cloning, expression, and purification of HLA-A2-BSP and beta-2m in Escherichia coli. Protein Expr. Purif. 35: 210-217 (2004). *
Picco P, Porfirio B, Gattorno M, Buoncompagni A, Falcini F, Cusano R, Bordo D, Pistoia V, Ravazzolo R, Seri M. MICA gene polymorphisms in an Italian paediatric series of juvenile Behcet disease. Int. J. Mol. Med. 10: 575-578 (2002).
Pichard V, Royer PJ, Richou C, Cauchin E, Goebes K, Gaignerie A, Masliah C, Gournay J, Gregoire M, Ferry N. Detection, isolation, and characterization of alpha-fetoprotein-specific T cell populations and clones using MHC class I multimer magnetic sorting. J. Immunother. 31: 246-253 (2008).
Pichler WJ, Beeler A, Keller M, Lerch M, Posadas S, Schmid D, Spanou Z, Zawodniak A, Gerber B. Pharmacological interaction of drugs with immune receptors: the p-i concept. Allergol. Int. 55: 17-25 (2006). *
Pichurin P, Pham N, David CS, Rapoport B, McLachlan SM. HLA-DR3 transgenic mice immunized with adenovirus encoding the thyrotropin receptor: T Cell epitopes and functional analysis of the CD40 Graves' polymorphism. Thyroid 16: 1221-1227 (2006).
Pichurin PN, Chazenbalk GD, Aliesky H, Pichurina O, Rapoport B, McLachlan SM. "Hijacking" the thyrotropin receptor: a chimeric receptor-lysosome associated membrane protein enhances deoxyribonucleic acid vaccination and induces Graves' hyperthyroidism. Endocrinology 145: 5504-5514 (2004). *
Piehl F, Olsson T. Inflammation and susceptibility to neurodegeneration: the use of unbiased genetics to decipher critical regulatory pathways. Neuroscience 158: 1143-1150 (2009).
Pierer M, Krause C, Hantzschel H. Extra-intestinal manifestations of chronic inflammatory bowel diseases. Z. Gastroenterol. 40 Suppl. 1: S92-S94 (2002).
Pieri L, Domenici L, Romagnoli P. A role for transforming growth factor-beta1 in maintaining the differentiated state of Langerhans cells in human epidermis. Ital. J. Anat. Embryol. 111: 133-149 (2006).
Pieters J. MHC class II restricted antigen presentation. Curr. Opin. Immunol. 9: 89-96 (1997).
Pietra G, Romagnani C, Moretta L, Mingari MC. HLA-E and HLA-E-bound peptides: recognition by subsets of NK and T cells. Curr. Pharm. Des. 15: 3336-3344 (2009).
Pietrangelo A. Hereditary hemochromatosis: the genes and the disease. Falk Symposium 156. XIII Falk Liver Week (Part II). GENETICS IN LIVER DISEASES, Freiburg (Germany), October 8-9, 2006, p. 25-26 (2006). *
Pietschmann K, Beetz S, Welte S, Martens I, Gruen J, Oberg HH, Wesch D, Kabelitz D. Toll-like receptor expression and function in subsets of human gammadelta T lymphocytes. Scand. J. Immunol. 70: 245-255 (2009). *
Pietz BC, Warden MB, Duchateau BK, Ellis TM. Multiplex genotyping of human minor histocompatibility antigens. Hum. Immunol. 66: 1174-1182 (2005).
Pinchuk IV, Saada JI, Beswick EJ, Boya G, Qiu SM, Mifflin RC, Raju GS, Reyes VE, Powell DW. PD-1 ligand expression by human colonic myofibroblasts/fibroblasts regulates CD4+ T-cell activity. Gastroenterology 135: 1228-1237.e2 (2008). *
Pinilla-Ibarz J, May RJ, Korontsvit T, Gomez M, Kappel B, Zakhaleva V, Zhang RH, Scheinberg DA. Improved human T-cell responses against synthetic HLA-0201 analog peptides derived from the WT1 oncoprotein. Leukemia 20: 2025-2033 (2006).
Pirmohamed M. Genetic factors in the predisposition to drug-induced hypersensitivity reactions. AAPS J. 8: E20-E26 (2006). *
Pirmohamed M, Arbuckle JB, Bowman CE, Brunner M, Burns DK, Delrieu O, Dix LP, Twomey JA, Stern RS. Investigation into the multidimensional genetic basis of drug-induced Stevens-Johnson syndrome and toxic epidermal necrolysis. Pharmacogenomics 8: 1661-1691 (2007).
Pirri A, Contieri FC, Benvenutti R, Bicalho MD. A study of HLA-G polymorphism and linkage disequilibrium in renal transplant patients and their donors. Transpl. Immunol. 20: 143-149 (2009).
Platt CD, Ma JK, Chalouni C, Ebersold M, Bou-Reslan H, Carano RA, Mellman I, Delamarre L. Mature dendritic cells use endocytic receptors to capture and present antigens. Proc. Natl. Acad. Sci. U.S.A. Feb 8 [Epub ahead of print] (2010). *
Plenge RM. Rheumatoid arthritis genetics: 2009 update. Curr. Rheumatol. Rep. 11: 351-356 (2009).
Plenge RM. Recent progress in rheumatoid arthritis genetics: one step towards improved patient care. Curr. Opin. Rheumatol. 21: 262-271 (2009).
Plenge RM, Criswell LA. Genetic variants that predict response to anti-tumor necrosis factor therapy in rheumatoid arthritis: current challenges and future directions. Curr. Opin. Rheumatol. 20: 145-152 (2008).
Pless DD, Ruthel G, Reinke EK, Ulrich RG, Bavari S. Persistence of zinc-binding bacterial superantigens at the surface of antigen-presenting cells contributes to the extreme potency of these superantigens as T-cell activators. Infect. Immun. 73: 5358-5366 (2005). *
Plevy SE, Targan SR, Yang H, Fernandez D, Rotter JI, Toyoda H. Tumor necrosis factor microsatellites define a Crohn's disease-associated haplotype on chromosome 6. Gastroenterology 110: 1053-1060 (1996). *
Plewnia G, Schulze K, Hunte C, Tampe R, Koch J. Modulation of the antigenic peptide transporter TAP by recombinant antibodies binding to the last five residues of TAP1. J. Mol. Biol. 369: 95-107 (2007). *
Ploski R, Undlien DE, Vinje O, Forre O, Thorsby E, Ronningen KS. Polymorphism of human major histocompatibility complex-encoded transporter associated with antigen processing (TAP) genes and susceptibility to juvenile rheumatoid arthritis. Hum. Immunol. 39: 54-60 (1994).
Pobezinskaya Y, Chervonsky AV, Golovkina TV. Initial stages of mammary tumor virus infection are superantigen independent. J. Immunol. 172: 5582-5587 (2004). *
Pociot F, McDermott MF. Genetics of type 1 diabetes mellitus. Genes Immun. 3: 235-249 (2002). *
Podolin PL, Bolognese BJ, Carpenter DC, Davis TG, Johanson RA, Fox JH, Long E 3rd, Dong X, Marquis RW, Locastro SM, Terfloth GJ, Kurali E, Peterson JJ, Smith BR, McQueney MS, Yamashita DS, Capper-Spudich EA. Inhibition of invariant chain processing, antigen-induced proliferative responses, and the development of collagen-induced arthritis and experimental autoimmune encephalomyelitis by a small molecule cysteine protease inhibitor. J. Immunol. 180: 7989-8003 (2008). *
Podolsky DK. The intestinal epithelium and IBD. Falk Symposium 146: GUT-LIVER INTERACTIONS: BASIC AND CLINICAL CONCEPTS, Innsbruck (Austria), March 11-12, 2005, pp. 24-25 (2005). *
Poggi A, Catellani S, Garuti A, Pierri I, Gobbi M, Zocchi MR. Effective in vivo induction of NKG2D ligands in acute myeloid leukaemias by all-trans-retinoic acid or sodium valproate. Leukemia 23: 641-648 (2009).
Poggi A, Catellani S, Musso A, Zocchi MR. Gammadelta T lymphocytes producing IFNgamma and IL-17 in response to Candida albicans or mycobacterial antigens: possible implications for acute and chronic inflammation. Curr. Med. Chem. 16: 4743-4749 (2009).
Poggi A, Prevosto C, Zancolli M, Canevali P, Musso A, Zocchi MR. NKG2D and natural cytotoxicity receptors are involved in natural killer cell interaction with self-antigen presenting cells and stromal cells. Ann. N. Y. Acad. Sci. 1109: 47-57 (2007). *
Poggi A, Zocchi MR. Human natural killer lymphocytes through the engagement of natural cytotoxicity receptors and NKG2D can trigger self-aggression. Autoimmun. Rev. 6: 295-299 (2007).
Poggi A, Zocchi MR. Antigen presenting cells and stromal cells trigger human natural killer lymphocytes to autoreactivity: evidence for the involvement of natural cytotoxicity receptors (NCR) and NKG2D. Clin. Dev. Immunol. 13: 325-336 (2006). *
Pohl C, Shishkova J, Schneider-Schaulies S. Viruses and dendritic cells: enemy mine. Cell. Microbiol. 9: 279-289 (2007). *
Pohlmann T, Bockmann RA, Grubmuller H, Uchanska-Ziegler B, Ziegler A, Alexiev U. Differential peptide dynamics is linked to major histocompatibility complex polymorphism. J. Biol. Chem. 279: 28197-28201 (2004). *
Polla BS, Gabert F, Peyrusse BM, Jacquier-Sarlin MR. Increased proteolysis of diphtheria toxin by human monocytes after heat shock: a subsidiary role for heat-shock protein 70 in antigen processing. Immunology 120: 230-241 (2007). *
Polvi A, Maki M, Partanen J. Celiac patients predominantly inherit HLA-DPB1*0101 positive haplotype from HLA-DQ2 homozygous parent. Hum. Immunol. 53: 156-158 (1997).
Pompos LJ, Fritsche KL. Antigen-driven murine CD4+ T lymphocyte proliferation and interleukin-2 production are diminished by dietary (n-3) polyunsaturated fatty acids. J. Nutr. 132: 3293-3300 (2002). *
Ponomarev ED, Shriver LP, Maresz K, Dittel BN. Microglial cell activation and proliferation precedes the onset of CNS autoimmunity. J. Neurosci. Res. 81: 374-389 (2005). *
Pope JE, Stevens A, Howson W, Bell DA. The development of rheumatoid arthritis after recombinant hepatitis B vaccination. J. Rheumatol. 25: 1687-1693 (1998).
Popescu I, Macedo C, Abu-Elmagd K, Shapiro R, Hua Y, Thomson AW, Morelli AE, Storkus WJ, Metes D. EBV-specific CD8(+) T cell reactivation in transplant patients results in expansion of CD8(+) type-1 regulatory T cells. Am. J. Transplant. 7: 1215-1223 (2007). *
Popov I, Li M, Zheng X, Sun H, Zhang X, Feng B, Vladau C, Zhong R, Garcia B, Strejan G, Inman RD, Min WP, Ichim TE, Suzuki M. Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine. Arthritis Res. Ther. 8: R141 (2006). *
Porporatto C, Bianco ID, Correa SG. Local and systemic activity of the polysaccharide chitosan at lymphoid tissues after oral administration. J. Leukoc. Biol. 78: 62-69 (2005). *
Portincasa P, Vacca M, Moschetta A, Petruzzelli M, Palasciano G, van-Erpecum KJ, van-Berge-Henegouwen GP. Primary sclerosing cholangitis: updates in diagnosis and therapy. World J. Gastroenterol. 11: 7-16 (2005). *
Porto I, Maria Leone A, Crea F, Andreotti F. Inflammation, genetics, and ischemic heart disease: focus on the major histocompatibility complex (MHC) genes. Cytokine 29: 187-196 (2005).
Poupon R. Primary biliary cirrhosis: a 2010 update. J. Hepatol. [In Press] (2010).
Poupon R, Poupon RE. Retrovirus infection as a trigger for primary biliary cirrhosis? Lancet 363: 260-261 (2004). *
Powell ND, Bailey MT, Mays JW, Stiner-Jones LM, Hanke ML, Padgett DA, Sheridan JF. Repeated social defeat activates dendritic cells and enhances Toll-like receptor dependent cytokine secretion. Brain Behav. Immun. 23: 225-231 (2009).
Powis SH, Rosenberg WM, Hall M, Mockridge I, Tonks S, Ivinson A, Ciclitira PJ, Jewell DP, Lanchbury JS, Bell JI, et al. TAP1 and TAP2 polymorphism in coeliac disease. Immunogenetics 38: 345-350 (1993).
Powis SH, Tonks S, Mockridge I, Kelly AP, Bodmer JG, Trowsdale J. Alleles and haplotypes of the MHC-encoded ABC transporters TAP1 and TAP2. Immunogenetics 37: 373-380 (1993).
Powis SJ, Nesbeth D, Lenart I, Fussell H, Gould K, Antoniou AN. Rapid acidification and alkylation: redox analysis of the MHC class I pathway. J. Immunol. Methods 340: 81-85 (2009). *
Pozsonyi E, Gyorgy B, Berki T, Banlaki Z, Buzas E, Rajczy K, Hosso A, Prohaszka Z, Szilagyi A, Cervenak L, Fust G. HLA-association of serum levels of natural antibodies. Mol. Immunol. 46: 1416-1423 (2009). *
Prasad A, Zikherman J, Das J, Roose JP, Weiss A, Chakraborty AK. Origin of the sharp boundary that discriminates positive and negative selection of thymocytes. Proc. Natl. Acad. Sci. U.S.A. 106: 528-533 (2009). *
Prasad S, Humphreys I, Kireta S, Gilchrist RB, Bardy P, Russ GR, Coates PT. The common marmoset as a novel preclinical transplant model: identification of new MHC class II DRB alleles and prediction of in vitro alloreactivity. Tissue Antigens 69 Suppl. 1: 72-75 (2007). *
Preda-Pais A, Stan AC, Casares S, Bona C, Brumeanu TD. Efficacy of clonal deletion vs. anergy of self-reactive CD4 T-cells for the prevention and reversal of autoimmune diabetes. J. Autoimmun. 25: 21-32 (2005).
Presnell SR, Zhang L, Ramilo CA, Chan HW, Lutz CT. Functional redundancy of transcription factor-binding sites in the killer cell Ig-like receptor (KIR) gene promoter. Int. Immunol. 18: 1221-1232 (2006). *
Preta G, Marescotti D, Fortini C, Carcoforo P, Castelli C, Masucci M, Gavioli R. Inhibition of serine-peptidase activity enhances the generation of a survivin-derived HLA-A2-presented CTL epitope in colon-carcinoma cells. Scand. J. Immunol. 68: 579-588 (2008). *
Price CL, Al Hassi HO, English NR, Blakemore AI, Stagg AJ, Knight SC. Methylglyoxal modulates immune responses: relevance to diabetes. J. Cell. Mol. Med. Jun 16 [Epub ahead of print] (2009). *
Price P, Calder DM, Witt CS, Allcock RJ, Christiansen FT, Davies GR, Cameron PU, Rogers M, Baluchova K, Moore CB, French MA. Periodontal attachment loss in HIV-infected patients is associated with the major histocompatibility complex 8.1 haplotype (HLA-A1,B8,DR3). Tissue Antigens 54: 391-399 (1999).
Price P, Cheong KY, Boodhoo A, Witt CS, McCann V, Christiansen FT, Allcock RJ. Can MHC class II genes mediate resistance to type 1 diabetes? Immunol. Cell Biol. 79: 602-606 (2001). *
Price P, Santoso L, Mastaglia F, Garlepp M, Kok CC, Allcock R, Laing N. Two major histocompatibility complex haplotypes influence susceptibility to sporadic inclusion body myositis: critical evaluation of an association with HLA-DR3. Tissue Antigens 64: 575-580 (2004). *
Price P, Witt C, Allcock R, Sayer D, Garlepp M, Kok CC, French M, Mallal S, Christiansen F. The genetic basis for the association of the 8.1 ancestral haplotype (A1, B8, DR3) with multiple immunopathological diseases. Immunol. Rev. 167: 257-274 (1999).
Price P, Wong AM, Williamson D, Voon D, Baltic S, Allcock RJ, Boodhoo A, Christiansen FT. Polymorphisms at positions -22 and -348 in the promoter of the BAT1 gene affect transcription and the binding of nuclear factors. Hum. Mol. Genet. 13: 967-974 (2004). *
Prignano F, Ricceri F, Bianchi B, Lotti T. Quantity, distribution and immunophenotypical modification of dendritic cells upon biological treatments in psoriasis. Int. J. Immunopathol. Pharmacol. 22: 379-387 (2009).
Probert CS, Saubermann LJ, Balk S, Blumberg RS. Repertoire of the alphabeta T-cell receptor in the intestine. Immunol. Rev. 215: 215-225 (2007). *
Prochorec-Sobieszek M, Wagner T, Loukas M, Chwalinska-Sadowska H, Olesinska M. Histopathological and immunohistochemical analysis of lymphoid follicles in labial salivary glands in primary and secondary Sjogren's syndrome. Med. Sci. Monit. 10: BR115-BR121 (2004). *
Procko E, Ferrin-O'Connell I, Ng SL, Gaudet R. Distinct structural and functional properties of the ATPase sites in an asymmetric ABC transporter. Mol. Cell. 24: 51-62 (2006). *
Procko E, Gaudet R. Antigen processing and presentation: TAPping into ABC transporters. Curr. Opin. Immunol. 21: 84-91 (2009).
Procko E, Raghuraman G, Wiley DC, Raghavan M, Gaudet R. Identification of domain boundaries within the N-termini of TAP1 and TAP2 and their importance in tapasin binding and tapasin-mediated increase in peptide loading of MHC class I. Immunol. Cell. Biol. 83: 475-482 (2005). *
Proft T, Fraser JD. Streptococcal superantigens. Chem. Immunol. Allergy 93: 1-23 (2007).
Pryhuber KG, Murray KJ, Donnelly P, Passo MH, Maksymowych WP, Glass DN, Giannini EH, Colbert RA. Polymorphism in the LMP2 gene influences disease susceptibility and severity in HLA-B27 associated juvenile rheumatoid arthritis. J. Rheumatol. 23: 747-752 (1996).
Pu Z, Lovitch SB, Bikoff EK, Unanue ER. T cells distinguish MHC-peptide complexes formed in separate vesicles and edited by H2-DM. Immunity 20: 467-476 (2004). *
Pua HH, Guo J, Komatsu M, He YW. Autophagy is essential for mitochondrial clearance in mature T lymphocytes. J. Immunol. 182: 4046-4055 (2009).
Pullmann R Jr, Lukac J, Skerenova M, Rovensky J, Hybenova J, Melus V, Celec S, Pullmann R, Hyrdel R. Cytotoxic T lymphocyte antigen 4 (CTLA-4) dimorphism in patients with systemic lupus erythematosus. Clin. Exp. Rheumatol. 17: 725-729 (1999).
Punnonen J, Aversa G, Cocks BG, McKenzie AN, Menon S, Zurawski G, de Waal Malefyt R, de Vries JE. Interleukin 13 induces interleukin 4-independent IgG4 and IgE synthesis and CD23 expression by human B cells. Proc. Natl. Acad. Sci. U.S.A. 90: 3730-3734 (1993). *
Purcell AW, Elliott T. Molecular machinations of the MHC-I peptide loading complex. Curr. Opin. Immunol. 20: 75-81 (2008). *
Purcell AW, van Driel IR, Gleeson PA. Impact of glycans on T-cell tolerance to glycosylated self-antigens. Immunol. Cell Biol. 86: 574-579 (2008). *
Purton JF, Tan JT, Rubinstein MP, Kim DM, Sprent J, Surh CD. Antiviral CD4+ memory T cells are IL-15 dependent. J. Exp. Med. 204: 951-961 (2007). *
Puttick A, Briggs D, Welsh K, Jacoby R, Williamson E, Jones V. Extended haplotypes in rheumatoid arthritis and preliminary evidence for an interaction with immunoglobulin genes. Dis. Markers 4: 139-144 (1986).
Puttick AH, Briggs DC, Welsh KI, Williamson EA, Jacoby RK, Jones VE. Genes associated with rheumatoid arthritis and mild inflammatory arthritis. II. Association of HLA with complement C3 and immunoglobulin Gm allotypes. Ann. Rheum. Dis. 49: 225-228 (1990). *
Qian BF, Tonkonogy SL, Sartor RB. Luminal bacterial antigen-specific CD4+ T-cell responses in HLA-B27 transgenic rats with chronic colitis are mediated by both major histocompatibility class II and HLA-B27 molecules. Immunology 117: 319-328 (2006). *
Qiao SW, Kobayashi K, Johansen FE, Sollid LM, Andersen JT, Milford E, Roopenian DC, Lencer WI, Blumberg RS. Dependence of antibody-mediated presentation of antigen on FcRn. Proc. Natl. Acad. Sci. U.S.A. 105: 9337-9342 (2008). *
Qin H, Zhou C, Wang D, Ma W, Liang X, Lin C, Zhang Y, Zhang S. Enhancement of antitumour immunity by a novel chemotactic antigen DNA vaccine encoding chemokines and multiepitopes of prostate-tumour-associated antigens. Immunology 117: 419-430 (2006). *
Qu C, Nguyen VA, Merad M, Randolph GJ. MHC class I/peptide transfer between dendritic cells overcomes poor cross-presentation by monocyte-derived APCs that engulf dying cells. J. Immunol. 182: 3650-3659 (2009).
Qu HQ, Marchand L, Szymborski A, Grabs R, Polychronakos C. The association between type 1 diabetes and the ITPR3 gene polymorphism due to linkage disequilibrium with HLA class II. Genes Immun. 9: 264-266 (2008). *
Qu HQ, Polychronakos C. The effect of the MHC locus on autoantibodies in type 1 diabetes. J. Med. Genet. 46: 469-471 (2009).
Quan TE, Roman RM, Rudenga BJ, Holers VM, Craft J. Epstein-Barr virus promotes interferon-alpha production by plasmacytoid dendritic cells. Arthritis Rheum. Feb 22 [Epub ahead of print] (2010).
Quaratino S, Badami E, Pang YY, Bartok I, Dyson J, Kioussis D, Londei M, Maiuri L. Degenerate self-reactive human T-cell receptor causes spontaneous autoimmune disease in mice. Nat. Med. 10: 920-926 (2004). *
Quarsten H, Paulsen G, Johansen BH, Thorpe CJ, Holm A, Buus S, Sollid LM. The P9 pocket of HLA-DQ2 (non-Aspbeta57) has no particular preference for negatively charged anchor residues found in other type 1 diabetes-predisposing non-Aspbeta57 MHC class II molecules. Int. Immunol. 10: 1229-1236 (1998). *
Quelvennec E, Bera O, Cabre P, Alizadeh M, Smadja D, Jugde F, Edan G, Semana G. Genetic and functional studies in multiple sclerosis patients from Martinique attest for a specific and direct role of the HLA-DR locus in the syndrome. Tissue Antigens 61: 166-171 (2003). *
Quinet EM, Savio DA, Halpern AR, Chen L, Miller CP, Nambi P. Gene-selective modulation by a synthetic oxysterol ligand of the liver X receptor. J. Lipid Res. 45: 1929-1942 (2004). *
Quintana FJ, Cohen IR. Anti-ergotypic immunoregulation. Scand. J. Immunol. 64: 205-210 (2006). *
Quintana FJ, Gerber D, Bloch I, Cohen IR, Shai Y. A structurally altered D,L-amino acid TCRalpha transmembrane peptide interacts with the TCRalpha and inhibits T-cell activation in vitro and in an animal model. Biochemistry 46: 2317-2325 (2007). *
Quintana FJ, Mimran A, Carmi P, Mor F, Cohen IR. HSP60 as a target of anti-ergotypic regulatory T cells. PLoS ONE 3: e4026 (2008). *
Racca AL, Veaute CM, Bailat AS, Gaite L, Arriola M, Hajos SE, Malan Borel IS. Expression of HLA-G and MICA mRNA in renal allograft. Transpl. Immunol. 21: 10-12 (2009).
Rad R, Brenner L, Krug A, Voland P, Mages J, Lang R, Schwendy S, Reindl W, Dossumbekova A, Ballhorn W, Wagner H, Schmid RM, Bauer S, Prinz C. Toll-like receptor-dependent activation of antigen-presenting cells affects adaptive immunity to Helicobacter pylori. Gastroenterology 133: 150-163.e3 (2007). *
Radaev S, Sun PD. Structure and function of natural killer cell surface receptors. Annu. Rev. Biophys. Biomol. Struct. 32: 93-114 (2003). *
Radford KJ, Turtle CJ, Kassianos AJ, Hart DN. CD11c+ blood dendritic cells induce antigen-specific cytotoxic T lymphocytes with similar efficiency compared to monocyte-derived dendritic cells despite higher levels of MHC class I expression. J. Immunother. 29: 596-605 (2006).
Radosavljevic M, Cuillerier B, Wilson MJ, Clement O, Wicker S, Gilfillan S, Beck S, Trowsdale J, Bahram S. A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3. Genomics 79: 114-123 (2002). *
Rafei M, Birman E, Forner K, Galipeau J. Allogeneic mesenchymal stem cells for treatment of experimental autoimmune encephalomyelitis. Mol. Ther. 17: 1799-1803 (2009).
Rafei M, Hsieh J, Zehntner S, Li M, Forner K, Birman E, Boivin MN, Young YK, Perreault C, Galipeau J. A granulocyte-macrophage colony-stimulating factor and interleukin-15 fusokine induces a regulatory B cell population with immune suppressive properties. Nat. Med. 15: 1038-1045 (2009). *
Raffegerst SH, Hoelzlwimmer G, Kunder S, Mysliwietz J, Quintanilla-Martinez L, Schendel DJ. Diverse hematological malignancies including hodgkin-like lymphomas develop in chimeric MHC class II transgenic mice. PLoS One 4: e8539 (2009). *
Rahman P. Genetics of ankylosing spondylitis: an update. Curr. Rheumatol. Rep. 9: 383-389 (2007).
Rahman P, Bartlett S, Siannis F, Pellett FJ, Farewell VT, Peddle L, Schentag CT, Alderdice CA, Hamilton S, Khraishi M, Tobin Y, Hefferton D, Gladman DD. CARD15: a pleiotropic autoimmune gene that confers susceptibility to psoriatic arthritis. Am. J. Hum. Genet. 73: 677-681 (2003). *
Rahman P, Elder JT. Genetic epidemiology of psoriasis and psoriatic arthritis. Ann. Rheum. Dis. 64 Suppl. 2: ii37-ii39 (2005). *
Raimondi G, Sumpter TL, Matta BM, Pillai M, Corbitt N, Vodovotz Y, Wang Z, Thomson AW. Mammalian target of rapamycin inhibition and alloantigen-specific regulatory T cells synergize to promote long-term graft survival in immunocompetent recipients. J. Immunol. 184: 624-636 (2010).
Raimondi G, Turner MS, Thomson AW, Morel PA. Naturally occurring regulatory T cells: recent insights in health and disease. Crit. Rev. Immunol. 27: 61-95 (2007).
Raine T, Allen R. MHC-I recognition by receptors on myelomonocytic cells: new tricks for old dogs? Bioessays 27: 542-550 (2005). *
Raine T, Brown D, Bowness P, Hill Gaston JS, Moffett A, Trowsdale J, Allen RL. Consistent patterns of expression of HLA class I free heavy chains in healthy individuals and raised expression in spondyloarthropathy patients point to physiological and pathological roles. Rheumatology (Oxford) 45: 1338-1344 (2006). *
Rajagopal D, Bal V, Mayor S, George A, Rath S. A role for the Hsp90 molecular chaperone family in antigen presentation to T lymphocytes via major histocompatibility complex class II molecules. Eur. J. Immunol. 36: 828-841 (2006). *
Rajagopalan G, Iijima K, Singh M, Kita H, Patel R, David CS. Intranasal exposure to bacterial superantigens induces airway inflammation in HLA class II transgenic mice. Infect. Immun. 74: 1284-1296 (2006). *
Rajagopalan G, Mangalam AK, Sen MM, Cheng S, Kudva YC, David CS. Autoimmunity in HLA-DQ8 transgenic mice expressing granulocyte/macrophage-colony stimulating factor in the beta cells of islets of Langerhans. Autoimmunity 40: 169-179 (2007).
Rajagopalan G, Mangalam AK, Sen MM, Kudva YC, David CS. Distinct local immunogenic stimuli dictate differential requirements for CD4(+) and CD8(+) T cell subsets in the pathogenesis of spontaneous autoimmune diabetes. Autoimmunity 40: 489-496 (2007).
Rajakaruna RS, Brown JA, Kaukinen KH, Miller KM. Major histocompatibility complex and kin discrimination in Atlantic salmon and brook trout. Mol. Ecol. 15: 4569-4575 (2006). *
Rajapakse M, Schmidt B, Feng L, Brusic V. Predicting peptides binding to MHC class II molecules using multi-objective evolutionary algorithms. BMC Bioinformatics 8: 459 (2007). *
Rajapakse M, Zhang GL, Srinivasan KN, Schmidt B, Petrovsky N, Brusic V. PREDNOD, a prediction server for peptide binding to the H-2g7 haplotype of the non-obese diabetic mouse. Autoimmunity 39: 645-650 (2006).
Rajasagi NK, Kassim SH, Kollias CM, Zhao X, Chervenak R, Jennings SR. CD4+ T cells are required for the priming of CD8+ T cells following infection with herpes simplex virus type 1. J. Virol. 83: 5256-5268 (2009). *
Rajashree P, Krishnan G, Das SD. Impaired phenotype and function of monocyte derived dendritic cells in pulmonary tuberculosis. Tuberculosis (Edinb.) 89: 77-83 (2009).
Rajsbaum R, Fici D, Boggs DA, Fraser PA, Flores-Villanueva PO, Awdeh ZL. Linkage disequilibrium between HLA-DPB1 alleles and retinoid X receptor beta haplotypes. Hum. Immunol. 63: 771-778 (2002).
Rajsbaum R, Fici D, Fraser PA, Flores-Villanueva PO, Awdeh ZL. Polymorphism of the human retinoid X receptor beta and linkage disequilibrium with HLA-DPB1. Tissue Antigens 58: 24-29 (2001). *
Raki M, Fallang LE, Brottveit M, Bergseng E, Quarsten H, Lundin KE, Sollid LM. Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients. Proc. Natl. Acad. Sci. U.S.A. 104: 2831-2836 (2007). *
Ramachandra L, Simmons D, Harding CV. MHC molecules and microbial antigen processing in phagosomes. Curr. Opin. Immunol. 21: 98-104 (2009).
Ramadeen A, Laurent G, Santos CC, Hu X, Connelly KA, Holub BJ, Mangat I, Dorian P. n-3 Polyunsaturated fatty acids alter expression of fibrotic and hypertrophic genes in a dog model of atrial cardiomyopathy. Heart Rhythm Dec 28 [Epub ahead of print] (2009).
Ramagopalan SV, Byrnes JK, Dyment DA, Guimond C, Handunnetthi L, Disanto G, Yee IM, Ebers GC, Sadovnick AD. Parent-of-origin of HLA-DRB1*1501 and age of onset of multiple sclerosis. J. Hum. Genet. 54: 547-549 (2009).
Ramagopalan SV, Dyment DA, Morrison KM, Herrera BM, Deluca GC, Lincoln MR, Orton SM, Handunnetthi L, Chao MJ, Sadovnick AD, Ebers GC. Methylation of class II transactivator gene promoter IV is not associated with susceptibility to multiple sclerosis. BMC Med. Genet. 9: 63 (2008). *
Ramagopalan SV, Dyment DA, Valdar W, Herrera BM, Criscuoli M, Yee IM, Sadovnick AD, Ebers GC; for the Canadian Collaborative Study Group. Autoimmune disease in families with multiple sclerosis: a population-based study. Lancet Neurol. 6: 604-610 (2007).
Ramagopalan SV, Ebers GC. Multiple sclerosis: major histocompatibility complexity and antigen presentation. Genome Med. 1: 105 (2009). *
Ramagopalan SV, Herrera BM, Bell JT, Dyment DA, Deluca GC, Lincoln MR, Orton SM, Chao MJ, Sadovnick AD, Ebers GC. Parental transmission of HLA-DRB1*15 in multiple sclerosis. Hum. Genet. 122: 661-663 (2008). *
Ramagopalan SV, Knight JC, Ebers GC. Multiple sclerosis and the major histocompatibility complex. Curr. Opin. Neurol. 22: 219-225 (2009).
Ramagopalan SV, Maugeri NJ, Handunnetthi L, Lincoln MR, Orton SM, Dyment DA, Deluca GC, Herrera BM, Chao MJ, Sadovnick AD, Ebers GC, Knight JC. Expression of the multiple sclerosis-associated MHC class II allele HLA-DRB1*1501 is regulated by vitamin D. PLoS Genet. 5: e1000369 (2009). *
Ramagopalan SV, McMahon R, Dyment DA, Sadovnick AD, Ebers GC, Wittkowski KM. An extension to a statistical approach for family based association studies provides insights into genetic risk factors for multiple sclerosis in the HLA-DRB1 gene. BMC Med. Genet. 10: 10 (2009). *
Ramagopalan SV, Morris AP, Dyment DA, Herrera BM, Deluca GC, Lincoln MR, Orton SM, Chao MJ, Sadovnick AD, Ebers GC. The inheritance of resistance alleles in multiple sclerosis. PLoS Genet. 3: e150 (2007). *
Ramakrishna J, Johnson AR, Banner BF. Long-term minocycline use for acne in healthy adolescents can cause severe autoimmune hepatitis. J. Clin. Gastroenterol. 43: 787-790 (2009).
Ramelli G, Fuertes S, Narayan S, Busso N, Acha-Orbea H, So A. Protease-activated receptor 2 signalling promotes dendritic cell antigen transport and T-cell activation in vivo. Immunology 129: 20-27 (2010). *
Ramirez-Anguiano J, Yamamoto-Furusho JK, Barquera R, Beltran O, Granados J. Association of HLA-DR3 and HLA-DR4 with sinonasal polyposis in Mexican Mestizos. Otolaryngol. Head Neck Surg. 135: 90-93 (2006).
Rammensee HG. Peptides made to order. Immunity 25: 693-695 (2006). *
Ramos PS, Langefeld CD, Bera LA, Gaffney PM, Noble JA, Moser KL. Variation in the ATP-binding cassette transporter 2 gene is a separate risk factor for systemic lupus erythematosus within the MHC. Genes Immun. 10: 350-355 (2009).
Randolph AG, Lange C, Silverman EK, Lazarus R, Weiss ST. Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma related phenotypes. Am. J. Respir. Crit. Care Med. 172: 687-692 (2005). *
Ranganathan P. An update on pharmacogenomics in rheumatoid arthritis with a focus on TNF-blocking agents. Curr. Opin. Mol. Ther. 10: 562-567 (2008).
Rani R, Sood A, Goswami R. Molecular basis of predisposition to develop type 1 diabetes mellitus in North Indians. Tissue Antigens 64: 145-155 (2004). *
Rani R, Sood A, Lazaro AM, Stastny P. Associations of MHC class II alleles with insulin-dependent diabetes mellitus (IDDM) in patients from North India. Hum. Immunol. 60: 524-531 (1999).
Rankin AL, Reed AJ, Oh S, Cozzo Picca C, Guay HM, Larkin J 3rd, Panarey L, Aitken MK, Koeberlein B, Lipsky PE, Tomaszewski JE, Naji A, Caton AJ. CD4+ T cells recognizing a single self-peptide expressed by APCs induce spontaneous autoimmune arthritis. J. Immunol. 180: 833-841 (2008). *
Rao X, Fontaine Costa AI, van Baarle D, Kesmir C. A comparative study of HLA binding affinity and ligand diversity: implications for generating immunodominant CD8+ T cell responses. J. Immunol. 182: 1526-1532 (2009).
Rapin N, Hoof I, Lund O, Nielsen M. MHC motif viewer. Immunogenetics 60: 759-765 (2008). *
Rashid S, Jin Y, Ecoiffier T, Barabino S, Schaumberg DA, Dana MR. Topical omega-3 and omega-6 fatty acids for treatment of dry eye. Arch. Ophthalmol. 126: 219-225 (2008).
Rasmussen HB, Kelly MA, Clausen J. Genetic susceptibility to multiple sclerosis: detection of polymorphic nucleotides and an intron in the 3' untranslated region of the major histocompatibility complex class II transactivator gene. Hum. Immunol. 62: 371-377 (2001).
Rasmusson I, Uhlin M, Le Blanc K, Levitsky V. Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes. J. Leukoc. Biol. 82: 887-893 (2007). *
Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello S, Silva GL, Evangelista AF, Magalhaes DA, Wastowski IJ, Crispim JO, Martelli-Palomino G, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Soares CP, Sakamoto-Hojo ET, Passos GA, Donadi EA. Gene expression profiles stratified according to type 1 diabetes mellitus susceptibility regions. Ann. N. Y. Acad. Sci. 1150: 282-289 (2008). *
Rassi DM, Junta CM, Fachin AL, Sandrin-Garcia P, Mello SS, Fernandes AP, Deghaide NN, Foss-Freitas MC, Foss MC, Sakamoto-Hojo ET, Passos GA, Donadi EA. Is HLA class II profile relevant for the study of large-scale differentially expressed genes in type 1 diabetes mellitus patients? Ann. N. Y. Acad. Sci. 1079: 305-309 (2006). *
Rassi DM, Wastowski IJ, Simoes RT, Rodrigues S, Deghaide NN, Mendes-Junior CT, Simoes AL, Soares CP, Passos GA, Donadi EA. TNFa-e microsatellite, HLA-DRB1 and -DQB1 alleles and haplotypes in Brazilian patients presenting recently diagnosed type 1 diabetes mellitus. Ann. N. Y. Acad. Sci. 1079: 300-304 (2006). *
Ratanachaiyavong S, Lloyd L, Darke C, McGregor AM. MHC-extended haplotypes in families of patients with Graves' disease. Hum. Immunol. 36: 99-111 (1993).
Rate A, Upham JW, Bosco A, McKenna KL, Holt PG. Airway epithelial cells regulate the functional phenotype of locally differentiating dendritic cells: implications for the pathogenesis of infectious and allergic airway disease. J. Immunol. 182: 72-83 (2009). *
Rathinam VA, Appledorn DM, Hoag KA, Amalfitano A, Mansfield LS. Campylobacter jejuni-induced activation of dendritic cells involves cooperative signaling through TLR4-MyD88 and TLR4-TRIF axes. Infect. Immun. 77: 2499-2507 (2009). *
Raulet DH, Vance RE. Self-tolerance of natural killer cells. Nat. Rev. Immunol. 6: 520-531 (2006). *
Raulet DH, Vance RE, McMahon CW. Regulation of the natural killer cell receptor repertoire. Annu. Rev. Immunol. 19: 291-330 (2001). *
Razi-Wolf Z, Galvin F, Gray G, Reiser H. Evidence for an additional ligand, distinct from B7, for the CTLA-4 receptor. Proc. Natl. Acad. Sci. U.S.A. 90: 11182-11186 (1993). *
Rea D, Laface D, Hutchins B, Kwappenberg K, Melief CJ, Hoeben RC, Offringa R. Recombinant adenovirus-transduced human dendritic cells engineered to secrete interleukin-10 (IL-10) suppress Th1-type responses while selectively activating IL-10-producing CD4(+) T cells. Hum. Immunol. 65: 1344-1355 (2004). *
Rebmann V, Schutt P, Brandhorst D, Opalka B, Moritz T, Reza Nowrousian M, Grosse-Wilde H. Soluble MICA as an independent prognostic factor for the overall survival and progression-free survival of multiple myeloma patients. Clin. Immunol. 123: 114-120 (2007). *
Reche PA, Reinherz EL. Definition of MHC supertypes through clustering of MHC peptide-binding repertoires. Methods Mol. Biol. 409: 163-173 (2007).
Redchenko I, Harrop R, Ryan MG, Hawkins RE, Carroll MW. Identification of a major histocompatibility complex class I-restricted T-cell epitope in the tumour-associated antigen, 5T4. Immunology 118: 50-57 (2006). *
Reddacliff LA, Beh K, McGregor H, Whittington RJ. A preliminary study of possible genetic influences on the susceptibility of sheep to Johne's disease. Aust. Vet. J. 83: 435-441 (2005).
Reddehase MJ. Antigens and immunoevasins: opponents in cytomegalovirus immune surveillance. Nat. Rev. Immunol. 2: 831-844 (2002).
Reddehase MJ, Simon CO, Seckert CK, Lemmermann N, Grzimek NK. Murine model of cytomegalovirus latency and reactivation. Curr. Top. Microbiol. Immunol. 325: 315-331 (2008).
Redmond WL, Weinberg AD. Targeting OX40 and OX40L for the treatment of autoimmunity and cancer. Crit. Rev. Immunol. 27: 415-436 (2007).
Rees LE, Jones P, Pinkerton K, Cogan T, Ayling SM, Belafsky P, Birchall MA. Exposure to environmental pollutants is related to sore throats and increased expression of HLA-DQ in the upper airway mucosa of man. Clin. Otolaryngol. 33: 642 (2008).
Regueiro JR, Arnaiz-Villena A. Human MHC class III (Bf, C2, C4) genes and GLO: their association with other HLA antigens and extended haplotypes in the Spanish population. Tissue Antigens 31: 14-25 (1988).
Rehm KE, Connor RF, Jones GJ, Yimbu K, Mannie MD, Roper RL. Vaccinia virus decreases major histocompatibility complex (MHC) class II antigen presentation, T-cell priming, and peptide association with MHC class II. Immunology 128: 381-392 (2009). *
Reichstetter S, Standifer NE, Geubtner KA, Liu AW, Agar SL, Kwok WW. Cytotoxic herpes simplex type 2-specific, DQ0602-restricted CD4 T-cell clones show alloreactivity to DQ0601. Immunology 117: 350-357 (2006). *
Reifsnyder P, Schott W, Pomerleau D, Lessard MD, Soper BW, Leiter EH. Bone marrow expressing a diabetes resistance MHC class II allele: diabetes deviation by chronic immune stimulation. Novartis Found. Symp. 292: 32-46 (2008).
Reifsnyder PC, Li R, Silveira PA, Churchill G, Serreze DV, Leiter EH. Conditioning the genome identifies additional diabetes resistance loci in type I diabetes resistant NOR/Lt mice. Genes Immun. 6: 528-538 (2005). *
Reipert BM, Steinitz KN, van Helden PM, Unterthurner S, Schuster M, Ahmad RU, Ilas J, Schwarz HP. Opportunities and limitations of mouse models humanized for HLA class II antigens. J. Thromb. Haemost. 7 Suppl. 1: 92-97 (2009).
Reis e Sousa C. Dendritic cells in a mature age. Nat. Rev. Immunol. 6: 476-483 (2006). *
Reis EA, Athanazio DA, McBride AJ, Azevedo TM, Magalhaes-Santos IF, Harn D, Reis MG. Influence of the HLA-DQB1*0201 allele on the immune response in a Schistosoma mansoni infection. Acta Trop. 108: 131-134 (2008).
Reith W, LeibundGut-Landmann S, Waldburger JM. Regulation of MHC class II gene expression by the class II transactivator. Nat. Rev. Immunol. 5: 793-806 (2005). *
Remondo C, Cereda V, Mostbock S, Sabzevari H, Franzusoff A, Schlom J, Tsang KY. Human dendritic cell maturation and activation by a heat-killed recombinant yeast (Saccharomyces cerevisiae) vector encoding carcinoembryonic antigen. Vaccine 27: 987-994 (2009). *
Renard C, Hart E, Sehra H, Beasley H, Coggill P, Howe K, Harrow J, Gilbert J, Sims S, Rogers J, Ando A, Shigenari A, Shiina T, Inoko H, Chardon P, Beck S. The genomic sequence and analysis of the swine major histocompatibility complex. Genomics 88: 96-110 (2006). *
Renella R, Picard C, Neven B, Ouachee-Chardin M, Casanova JL, Deist FL, Cavazzana-Calvo M, Blanche S, Fischer A. Human leucocyte antigen-identical haematopoietic stem cell transplantation in major histocompatiblity complex class II immunodeficiency: reduced survival correlates with an increased incidence of acute graft-versus-host disease and pre-existing viral � Br. J. Haematol. 134: 510-516 (2006). *
Rennalls LP, Seidl T, Larkin JM, Wellbrock C, Gore ME, Eisen T, Bruno L. The melanocortin receptor agonist NDP-MSH impairs the allostimulatory function of dendritic cells. Immunology Jan 13 [Epub ahead of print] (2010). *
Restrepo D, Lin W, Salcedo E, Yamazaki K, Beauchamp G. Odortypes and MHC peptides: complementary chemosignals of MHC haplotype? Trends Neurosci. 29: 604-609 (2006). *
Reveille JD. Recent studies on the genetic basis of ankylosing spondylitis. Curr. Rheumatol. Rep. 11: 340-348 (2009).
Reveille JD. The genetic basis of spondyloarthritis. Curr. Rheumatol. Rep. 6: 117-125 (2004).
Reveille JD. The genetic contribution to the pathogenesis of rheumatoid arthritis. Curr. Opin. Rheumatol. 10: 187-200 (1998).
Reveille JD. The genetic basis of autoantibody production. Autoimmun. Rev. 5: 389-398 (2006).
Reveille JD. Major histocompatibility genes and ankylosing spondylitis. Best Pract. Res. Clin. Rheumatol. 20: 601-609 (2006).
Reveille JD. The genetic basis of ankylosing spondylitis. Curr. Opin. Rheumatol. 18: 332-341 (2006).
Reveille JD. Genetic studies in the rheumatic diseases: present status and implications for the future. J. Rheumatol. Suppl. 72: 10-13 (2005). *
Reveille JD, Arnett FC. Spondyloarthritis: update on pathogenesis and management. Am. J. Med. 118: 592-603 (2005). *
Reveille JD, Ball EJ, Khan MA. HLA-B27 and genetic predisposing factors in spondyloarthropathies. Curr. Opin. Rheumatol. 13: 265-272 (2001).
Reyburn H, Mandelboim O, Vales-Gomez M, Sheu EG, Pazmany L, Davis DM, Strominger JL. Human NK cells: their ligands, receptors and functions. Immunol. Rev. 155: 119-125 (1997).
Reynolds RJ, Kelley JM, Hughes LB, Yi N, Bridges SL Jr. Genetic association of htSNPs across the major histocompatibility complex with rheumatoid arthritis in an African-American population. Genes Immun. Sep 10 [Epub ahead of print] (2009).
Rezzani R, Pompili E, Agostini C, Buffoli B, Bonomini F, Nori S, Fumagalli L, Bianchi R. Expression of non-muscle myosin heavy chain in rat heart after immunosuppressive treatment. Int. Immunopharmacol. 6: 962-967 (2006).
Rhodes DA, Stammers M, Malcherek G, Beck S, Trowsdale J. The cluster of BTN genes in the extended major histocompatibility complex. Genomics 71: 351-362 (2001). *
Rhodes DA, Trowsdale J. Genetics and molecular genetics of the MHC. Rev. Immunogenet. 1: 21-31 (1999).
Ribas F, Oliveira LA, Petzl-Erler ML, Bicalho MG. Major histocompatibility complex class I chain-related gene A polymorphism and linkage disequilibrium with HLA-B alleles in Euro-Brazilians. Tissue Antigens 72: 532-538 (2008). *
Ribot J, Enault G, Pilipenko S, Huchenq A, Calise M, Hudrisier D, Romagnoli P, van Meerwijk JP. Shaping of the autoreactive regulatory T cell repertoire by thymic cortical positive selection. J. Immunol. 179: 6741-6748 (2007). *
Rice J, Dossett ML, Ohlen C, Buchan SL, Kendall TJ, Dunn SN, Stevenson FK, Greenberg PD. DNA fusion gene vaccination mobilizes effective anti-leukemic cytotoxic T lymphocytes from a tolerized repertoire. Eur. J. Immunol. 38: 2118-2130 (2008). *
Rich SS, Akolkar B, Concannon P, Erlich H, Hilner JE, Julier C, Morahan G, Nerup J, Nierras C, Pociot F, Todd JA. Current status and the future for the genetics of type I diabetes. Genes Immun. 10: S128-S131 (2009).
Richeldi L, Sorrentino R, Saltini C. HLA-DPB1 glutamate 69: a genetic marker of beryllium disease. Science 262: 242-244 (1993). *
Richman SA, Healan SJ, Weber KS, Donermeyer DL, Dossett ML, Greenberg PD, Allen PM, Kranz DM. Development of a novel strategy for engineering high-affinity proteins by yeast display. Protein Eng. Des. Sel. 19: 255-264 (2006). *
Richman SA, Kranz DM. Display, engineering, and applications of antigen-specific T cell receptors. Biomol. Eng. 24: 361-373 (2007). *
Rickert U, Welke J, Behrens D, Zavazava N. A divalent human leukocyte antigen-B7 fusion-protein up-regulates CD25 and CD69 in alloreactive CD8+ T cells bypassing CD28 costimulation. Transplantation 81: 1337-1344 (2006).
Ridwan R, Kiptoo P, Kobayashi N, Weir S, Hughes M, Williams T, Soegianto R, Siahaan TJ. Antigen-specific suppression of experimental autoimmune encephalomyelitis by a novel bifunctional peptide inhibitor: structure optimization and pharmacokinetics. J. Pharmacol. Exp. Ther. Dec 21 [Epub ahead of print] (2009). *
Riedl P, Reimann J, Schirmbeck R. Complexes of DNA vaccines with cationic, antigenic peptides are potent, polyvalent CD8+ T-cell-stimulating immunogens. Methods Mol. Med. 127: 159-170 (2006).
Rieser C, Bock G, Klocker H, Bartsch G, Thurnher M. Prostaglandin E2 and tumor necrosis factor alpha cooperate to activate human dendritic cells: synergistic activation of interleukin 12 production. J. Exp. Med. 186: 1603-1608 (1997). *
Rinderknecht CH, Belmares MP, Catanzarite TL, Bankovich AJ, Holmes TH, Garcia KC, Nanda NK, Busch R, Kovats S, Mellins ED. Posttranslational regulation of I-Ed by affinity for CLIP. J. Immunol. 179: 5907-5915 (2007). *
Rink L, Haase H. Zinc homeostasis and immunity. Trends Immunol. 28: 1-4 (2007). *
Rintisch C, Forster M, Holmdahl R. Detection of arthritis-susceptibility loci, including Ncf1, and variable effects of the major histocompatibility complex region depending on genetic background in rats. Arthritis Rheum. 60: 419-427 (2009). *
Rios A, Rodriguez JM, Moya MR, Galindo PJ, Canteras M, Alvarez MR, Parrilla P. Associations of HLA-C alleles with multinodular goiters: study in a population from southeastern Spain. Arch. Surg. 141: 123-128 (2006). *
Rist M, Smith C, Bell MJ, Burrows SR, Khanna R. Cross-recognition of HLA DR4 alloantigen by virus-specific CD8+ T cells: a new paradigm for self/non-self recognition. Blood 114: 2244-2253 (2009). *
Ristich V, Zhang W, Liang S, Horuzsko A. Mechanisms of prolongation of allograft survival by HLA-G/ILT4-modified dendritic cells. Hum. Immunol. 68: 264-271 (2007).
Ritchlin CT. Pathogenesis of psoriatic arthritis. Curr. Opin. Rheumatol. 17: 406-412 (2005).
Rival C, Theas M, Suescun M, Jacobo P, Guazzone V, van Rooijen N, Lustig L. Functional and phenotypic characteristics of testicular macrophages in experimental autoimmune orchitis. J. Pathol. 215: 108-117 (2008). *
Rizvi SM, Raghavan M. Direct peptide-regulatable interactions between MHC class I molecules and tapasin. Proc. Natl. Acad. Sci. U.S.A. 103: 18220-18225 (2006). *
Rizzo R, Campioni D, Stignani M, Melchiorri L, Bagnara G, Bonsi L, Alviano F, Lanzoni G, Moretti S, Cuneo A, Lanza F, Baricordi O. A functional role for soluble HLA-G antigens in immune modulation mediated by mesenchymal stromal cells. Cytotherapy 10: 364-375 (2008).
Rizzo R, Melchiorri L, Simone L, Stignani M, Marzola A, Gullini S, Baricordi OR. Different production of soluble HLA-G antigens by peripheral blood mononuclear cells in ulcerative colitis and Crohn's disease: a noninvasive diagnostic tool? Inflamm. Bowel Dis. 14: 100-105 (2008). *
Rizzo R, Rubini M, Govoni M, Padovan M, Melchiorri L, Stignani M, Carturan S, Ferretti S, Trotta F, Baricordi OR. HLA-G 14-bp polymorphism regulates the methotrexate response in rheumatoid arthritis. Pharmacogenet. Genomics 16: 615-623 (2006).
Roach JC, Deutsch K, Li S, Siegel AF, Bekris LM, Einhaus DC, Sheridan CM, Glusman G, Hood L, Lernmark A, Janer M; Swedish Childhood Diabetes Study Group and the Diabetes Incidence in Sweden Study Group. Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden. Am. J. Hum. Genet. 79: 614-627 (2006). *
Roberts SC, Little AC, Gosling LM, Jones BC, Perrett DI, Carter V, Petrie M. MHC-assortative facial preferences in humans. Biol. Lett. 1: 400-403 (2005).
Roberts-Thomson PJ, Roberts-Thomson RA, Nikoloutsopoulos T, Gillis D. Immune dysfunction in Australian Aborigines. Asian Pac. J. Allergy Immunol. 23: 235-244 (2005).
Robertson JM, Macleod M, Marsden VS, Kappler JW, Marrack P. Not all CD4 memory T cells are long lived. Immunol. Rev. 211: 49-57 (2006). *
Robertson NJ, Chai JG, Millrain M, Scott D, Hashim F, Manktelow E, Lemonnier F, Simpson E, Dyson J. Natural regulation of immunity to minor histocompatibility antigens. J. Immunol. 178: 3558-3565 (2007). *
Robila V, Ostankovitch M, Altrich-Vanlith ML, Theos AC, Drover S, Marks MS, Restifo N, Engelhard VH. MHC class II presentation of gp100 epitopes in melanoma cells requires the function of conventional endosomes and is influenced by melanosomes. J. Immunol. 181: 7843-7852 (2008). *
Robinson CP, Yamachika S, Bounous DI, Brayer J, Jonsson R, Holmdahl R, Peck AB, Humphreys-Beher MG. A novel NOD-derived murine model of primary Sjogren's syndrome. Arthritis Rheum. 41: 150-156 (1998). *
Robinson J, Malik A, Parham P, Bodmer JG, Marsh SG. IMGT/HLA database - a sequence database for the human major histocompatibility complex. Tissue Antigens 55: 280-287 (2000). *
Robinson J, Mistry K, McWilliam H, Lopez R, Marsh SG. IPD - the Immuno Polymorphism Database. Nucleic Acids Res. 38: D863-D869 (2010). *
Robinson J, Waller MJ, Fail SC, Marsh SG. The IMGT/HLA and IPD databases. Hum. Mutat. 27: 1192-1199 (2006). *
Robinson J, Waller MJ, Parham P, Bodmer JG, Marsh SG. IMGT/HLA database - a sequence database for the human major histocompatibility complex. Nucleic Acids Res. 29: 210-213 (2001). *
Robinson J, Waller MJ, Stoehr P, Marsh SG. IPD - the Immuno Polymorphism Database. Nucleic Acids Res. 33 Database Issue: D523-D526 (2005). *
Robson NC, Hoves S, Maraskovsky E, Schnurr M. Presentation of tumour antigens by dendritic cells and challenges faced. Curr. Opin. Immunol. Jan 28 [Epub ahead of print] (2010).
Rocha-Ramirez LM, Estrada-Garcia I, Lopez-Marin LM, Segura-Salinas E, Mendez-Aragon P, Van Soolingen D, Torres-Gonzalez R, Chacon-Salinas R, Estrada-Parra S, Maldonado-Bernal C, Lopez-Macias C, Isibasi A. Mycobacterium tuberculosis lipids regulate cytokines, TLR-2/4 and MHC class II expression in human macrophages. Tuberculosis (Edinb.) 88: 212-220 (2008). *
Rock F, Hadeler KP, Rammensee HG, Overath P. Quantitative analysis of mouse urine volatiles: in search of MHC-dependent differences. PLoS ONE 2: e429 (2007). *
Rock KL, Farfan-Arribas DJ, Shen L. Proteases in MHC class I presentation and cross-presentation. J. Immunol. 184: 9-15 (2010).
Rock RB, Hu S, Deshpande A, Munir S, May BJ, Baker CA, Peterson PK, Kapur V. Transcriptional response of human microglial cells to interferon-gamma. Genes Immun. 6: 712-719 (2005). *
Roda-Navarro P, Vales-Gomez M, Chisholm SE, Reyburn HT. Transfer of NKG2D and MICB at the cytotoxic NK cell immune synapse correlates with a reduction in NK cell cytotoxic function. Proc. Natl. Acad. Sci. U.S.A. 103: 11258-11263 (2006). *
Roddis M, Carter RW, Sun MY, Weissensteiner T, McMichael AJ, Bowness P, Bodmer HC. Fully functional HLA B27-restricted CD4+ as well as CD8+ T cell responses in TCR transgenic mice. J. Immunol. 172: 155-161 (2004). *
Rodeberg DA, Nuss RA, Elsawa SF, Erskine CL, Celis E. Generation of tumoricidal PAX3 peptide antigen specific cytotoxic T lymphocytes. Int. J. Cancer 119: 126-132 (2006). *
Rodenko B, Toebes M, Hadrup SR, van Esch WJ, Molenaar AM, Schumacher TN, Ovaa H. Generation of peptide-MHC class I complexes through UV-mediated ligand exchange. Nat. Protoc. 1: 1120-1132 (2006). *
Roder G, Geironson L, Darabi A, Harndahl M, Schafer-Nielsen C, Skjodt K, Buus S, Paulsson K. The outermost N-terminal region of tapasin facilitates folding of major histocompatibility complex class I. Eur. J. Immunol. 39: 2682-2694 (2009). *
Rodgers JR, Cook RG. MHC class Ib molecules bridge innate and acquired immunity. Nat. Rev. Immunol. 5: 459-471 (2005). *
Rodgers W, Smith K. Properties of glycolipid-enriched membrane rafts in antigen presentation. Crit. Rev. Immunol. 25: 19-30 (2005).
Rodo J, Goncalves LA, Demengeot J, Coutinho A, Penha-Goncalves C. MHC class II molecules control murine B cell responsiveness to lipopolysaccharide stimulation. J. Immunol. 177: 4620-4626 (2006). *
Rodrigues RM, Silva NM, Goncalves AL, Cardoso CR, Alves R, Goncalves FA, Beletti ME, Ueta MT, Silva JS, Costa-Cruz JM. Major histocompatibility complex (MHC) class II but not MHC class I molecules are required for efficient control of Strongyloides venezuelensis infection in mice. Immunology 128: e432-e441 (2009). *
Rodriguez M, Zoecklein L, Kerkvliet JG, Pavelko KD, Papke L, Howe CL, Pease LR, David C. Human HLA DR transgenes protect mice from fatal virus-induced encephalomyelitis and chronic demyelination. J. Virol. 82: 3369-3380 (2008). *
Rodriguez T, Mendez R, Del Campo A, Aptsiauri N, Martin J, Orozco G, Pawelec G, Schadendorf D, Ruiz-Cabello F, Garrido F. Patterns of constitutive and IFN-gamma inducible expression of HLA class II molecules in human melanoma cell lines. Immunogenetics 59: 123-133 (2007). *
Rodriguez-Perez JM, Fragoso JM, Alvarez-Leon E, Martinez-Rodriguez N, Gallardo GJ, Ines-Real S, Granados J, Reyes PA, Vargas-Alarcon G. MHC class II genes in Mexican patients with idiopathic dilated cardiomyopathy. Exp. Mol. Pathol. 82: 49-52 (2007). *
Rodriguez-Reyna TS, Alarcon-Segovia D. The different faces of shared autoimmunity. Autoimmun. Rev. 5: 86-88 (2006).
Rodriguez-Rodero S, Gonzalez S, Rodrigo L, Fernandez-Morera JL, Martinez-Borra J, Lopez-Vazquez A, Lopez-Larrea C. Transcriptional regulation of MICA and MICB: a novel polymorphism in MICB promoter alters transcriptional regulation by Sp1. Eur. J. Immunol. 37: 1938-1953 (2007). *
Rodriguez-Rodero S, Rodrigo L, Fdez-Morera JL, Martinez-Borra J, Lopez-Vazquez A, Fuentes D, Lopez-Arbesu R, Lopez-Soto A, Gonzalez S, Lopez-Larrea C. MHC class I chain-related gene B promoter polymorphisms and celiac disease. Hum. Immunol. 67: 208-214 (2006).
Rodriguez-Sosa M, Satoskar AR, Calderon R, Gomez-Garcia L, Saavedra R, Bojalil R, Terrazas LI. Chronic helminth infection induces alternatively activated macrophages expressing high levels of CCR5 with low interleukin-12 production and Th2-biasing ability. Infect. Immun. 70: 3656-3664 (2002). *
Rogers J, Hakki A, Perkins I, Newton C, Widen R, Burdash N, Klein T, Friedman H. Legionella pneumophila infection up-regulates dendritic cell TLR 2/4 expression and key maturation markers. Infect. Immun. 75: 3205-3208 (2007). *
Roghanian A, Drost EM, Macnee W, Howie SE, Sallenave JM. Inflammatory lung secretions inhibit dendritic cell maturation and function via neutrophil elastase. Am. J. Respir. Crit. Care Med. 174: 1189-1198 (2006). *
Rohrlich PS, Fazilleau N, Ginhoux F, Firat H, Michel F, Cochet M, Laham N, Roth MP, Pascolo S, Nato F, Coppin H, Charneau P, Danos O, Acuto O, Ehrlich R, Kanellopoulos J, Lemonnier FA. Direct recognition by alphabeta cytolytic T cells of Hfe, a MHC class Ib molecule without antigen-presenting function. Proc. Natl. Acad. Sci. U.S.A. 102: 12855-12860 (2005). *
Rojas Ramos E, Cisneros Gonzalez N, Cairo Cueto SM. Superantigens in human disease. Rev. Alerg. Mex. 44: 77-82 (1997).
Rolli V, Radosavljevic M, Astier V, Macquin C, Castan-Laurell I, Visentin V, Guigne C, Carpene C, Valet P, Gilfillan S, Bahram S. Lipolysis is altered in MHC class I zinc-alpha(2)-glycoprotein deficient mice. FEBS Lett. 581: 394-400 (2007). *
Rolstad B, Seaman WE. Natural killer cells and recognition of MHC class I molecules: new perspectives and challenges in immunology. Scand. J. Immunol. 47: 412-425 (1998). *
Romagnani C, Pietra G, Falco M, Mazzarino P, Moretta L, Mingari MC. HLA-E-restricted recognition of human cytomegalovirus by a subset of cytolytic T lymphocytes. Hum. Immunol. 65: 437-445 (2004).
Romagnoli P, Tellier J, van Meerwijk JP. Genetic control of thymic development of CD4(+)CD25(+)FoxP3(+) regulatory T lymphocytes. Eur. J. Immunol. 35: 3525-3532 (2005). *
Romano A, De Santis A, Romito A, Di Fonso M, Venuti A, Gasbarrini GB, Manna R. Delayed hypersensitivity to aminopenicillins is related to major histocompatibility complex genes. Ann. Allergy Asthma Immunol. 80: 433-437 (1998). *
Romero V, Azocar J, Zuniga J, Clavijo OP, Terreros D, Gu X, Husain Z, Chung RT, Amos C, Yunis EJ. Interaction of NK inhibitory receptor genes with HLA-C and MHC class II alleles in hepatitis C virus infection outcome. Mol. Immunol. 45: 2429-2436 (2008). *
Romero V, Larsen CE, Duke-Cohan JS, Fox EA, Romero T, Clavijo OP, Fici DA, Husain Z, Almeciga I, Alford DR, Awdeh ZL, Zuniga J, El-Dahdah L, Alper CA, Yunis EJ. Genetic fixity in the human major histocompatibility complex and block size diversity in the class I region including HLA-E. BMC Genet. 8: 14 (2007). *
Romphruk AV, Naruse TK, Romphruk A, Kawata H, Puapairoj C, Kulski JK, Leelayuwat C, Inoko H. Diversity of MICA (PERB11.1) and HLA haplotypes in Northeastern Thais. Tissue Antigens 58: 83-89 (2001). *
Romphruk AV, Oka A, Romphruk A, Tomizawa M, Choonhakarn C, Naruse TK, Puapairoj C, Tamiya G, Leelayuwat C, Inoko H. Corneodesmosin gene: no evidence for PSORS 1 gene in North-eastern Thai psoriasis patients. Tissue Antigens 62: 217-224 (2003). *
Romphruk AV, Romphruk A, Choonhakarn C, Puapairoj C, Inoko H, Leelayuwat C. Major histocompatibility complex class I chain-related gene A in Thai psoriasis patients: MICA association as a part of human leukocyte antigen-B-Cw haplotypes. Tissue Antigens 63: 547-554 (2004). *
Rose NR. Prediction and prevention of autoimmune disease: a personal perspective. Ann. N. Y. Acad. Sci. 1109: 117-128 (2007). *
Rosenberg AS. Effects of protein aggregates: an immunologic perspective. AAPS J. 8: E501-E507 (2006). *
Rosenberg SA, Sherry RM, Morton KE, Yang JC, Topalian SL, Royal RE, Kammula US, Restifo NP, Hughes MS, Schwarz SL, Ngo LT, Mavroukakis SA, White DE. Altered CD8+ T-cell responses when immunizing with multiepitope peptide vaccines. J. Immunother. 29: 224-231 (2006). *
Roshna T, Thomas R, Nandakumar K, Banerjee M. A case-control study on the association of human leukocyte antigen-A*9 and -B*15 alleles with generalized aggressive periodontitis in an Indian population. J. Periodontol. 77: 1954-1963 (2006).
Rosloniec EF, Brandstetter T, Leyer S, Schwaiger FW, Nagy ZA. Second-generation peptidomimetic inhibitors of antigen presentation effectively treat autoimmune diseases in HLA-DR-transgenic mouse models. J. Autoimmun. 27: 182-195 (2006).
Rosloniec EF, Ivey RA 3rd, Whittington KB, Kang AH, Park HW. Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen. J. Immunol. 177: 3884-3892 (2006). *
Roudier J. Association of MHC and rheumatoid arthritis. Association of RA with HLA-DR4: the role of repertoire selection. Arthritis Res. 2: 217-220 (2000). *
Roujeau JC. Immune mechanisms in drug allergy. Allergol. Int. 55: 27-33 (2006). *
Roujeau JC, Huynh TN, Bracq C, Guillaume JC, Revuz J, Touraine R. Genetic susceptibility to toxic epidermal necrolysis. Arch. Dermatol. 123: 1171-1173 (1987).
Rubin B. Natural immunity has significant impact on immune responses against cancer. Scand. J. Immunol. 69: 275-290 (2009). *
Rubin B, Riond J, Leghait J, Gairin JE. Interactions between CD8alphabeta and the TCRalphabeta/CD3-receptor complex. Scand. J. Immunol. 64: 260-270 (2006). *
Rubin B, Sonderstrup G. Citrullination of self-proteins and autoimmunity. Scand. J. Immunol. 60: 112-120 (2004). *
Rubin LA, Amos CI, Wade JA, Martin JR, Bale SJ, Little AH, Gladman DD, Bonney GE, Rubenstein JD, Siminovitch KA. Investigating the genetic basis for ankylosing spondylitis. Linkage studies with the major histocompatibility complex region. Arthritis Rheum. 37: 1212-1220 (1994).
Rubio JP, Speed TP, Bahlo M, Kilpatrick TJ, Foote SJ. The current state of multiple sclerosis genetic research. Ann. Acad. Med. Singapore 29: 322-330 (2000).
Ruckert C, Fiorillo MT, Loll B, Moretti R, Biesiadka J, Saenger W, Ziegler A, Sorrentino R, Uchanska-Ziegler B. Conformational dimorphism of self-peptides and molecular mimicry in a disease-associated HLA-B27 subtype. J. Biol. Chem. 281: 2306-2316 (2006). *
Ruckert R, Brandt K, Ernst M, Marienfeld K, Csernok E, Metzler C, Budagian V, Bulanova E, Paus R, Bulfone-Paus S. Interleukin-15 stimulates macrophages to activate CD4(+) T cells: a role in the pathogenesis of rheumatoid arthritis? Immunology 126: 63-73 (2009). *
Ruckrich T, Brandenburg J, Cansier A, Muller M, Stevanovic S, Schilling K, Wiederanders B, Beck A, Melms A, Reich M, Driessen C, Kalbacher H. Specificity of human cathepsin S determined by processing of peptide substrates and MHC class II-associated invariant chain. Biol. Chem. 387: 1503-1511 (2006).
Rudd BD, Brien JD, Davenport MP, Nikolich-Zugich J. Cutting edge: TLR ligands increase TCR triggering by slowing peptide-MHC class I decay rates. J. Immunol. 181: 5199-5203 (2008). *
Rudd PM, Wormald MR, Dwek RA. Sugar-mediated ligand-receptor interactions in the immune system. Trends Biotechnol. 22: 524-530 (2004). *
Rudolph MG, Stanfield RL, Wilson IA. How TCRs bind MHCs, peptides, and coreceptors. Annu. Rev. Immunol. 24: 419-466 (2006). *
Rueda B, Pascual M, Lopez-Nevot MA, Gonzalez E, Martin J. A new allele within the transmembrane region of the human MICA gene with seven GCT repeats. Tissue Antigens 60: 526-528 (2002). *
Rumbo M, Schiffrin EJ. Ontogeny of intestinal epithelium immune functions: developmental and environmental regulation. Cell. Mol. Life Sci. 62: 1288-1296 (2005). *
Runstadler JA, Saila H, Savolainen A, Leirisalo-Repo M, Aho K, Tuomilehto-Wolf E, Tuomilehto J, Seldin MF. HLA-DRB1, TAP2/TAP1, and HLA-DPB1 haplotypes in Finnish juvenile idiopathic arthritis: more complexity within the MHC. Genes Immun. 5: 562-571 (2004). *
Runstadler JA, Saila H, Savolainen A, Leirisalo-Repo M, Aho K, Tuomilehto-Wolf E, Tuomilehto J, Seldin MF. Analysis of MHC region genetics in Finnish patients with juvenile idiopathic arthritis: evidence for different locus-specific effects in polyarticular vs pauciarticular subsets and a shared DRB1 epitope. Genes Immun. 4: 326-335 (2003). *
Rusakiewicz S, Aubert G, Clark RE, Madrigal AJ, Dodi AI, Travers PJ. Soluble HLA/peptide monomers cross-linked with co-stimulatory antibodies onto a streptavidin core molecule efficiently stimulate antigen-specific T cell responses. Cancer Immunol. Immunother. 58: 1459-1470 (2009). *
Ryan EJ, Magaletti D, Draves KE, Clark EA. Ligation of dendritic cell-associated lectin-1 induces partial maturation of human monocyte derived dendritic cells. Hum. Immunol. 70: 1-5 (2009).
Ryan KR, Patel SD, Stephens LA, Anderton SM. Death, adaptation and regulation: the three pillars of immune tolerance restrict the risk of autoimmune disease caused by molecular mimicry. J. Autoimmun. 29: 262-271 (2007).
Rybicki BA, Maliarik MJ, Poisson LM, Iannuzzi MC. Sarcoidosis and granuloma genes: a family-based study in African-Americans. Eur. Respir. J. 24: 251-257 (2004). *
Rybicki BA, Walewski JL, Maliarik MJ, Kian H, Iannuzzi MC; ACCESS Research Group. The BTNL2 gene and sarcoidosis susceptibility in African Americans and Whites. Am. J. Hum. Genet. 77: 491-499 (2005). *
Rydstrom A, Wick MJ. Monocyte recruitment, activation, and function in the gut-associated lymphoid tissue during oral Salmonella infection. J. Immunol. 178: 5789-5801 (2007). *
Sa-Nunes A, Bafica A, Lucas DA, Conrads TP, Veenstra TD, Andersen JF, Mather TN, Ribeiro JM, Francischetti IM. Prostaglandin E2 is a major inhibitor of dendritic cell maturation and function in Ixodes scapularis saliva. J. Immunol. 179: 1497-1505 (2007). *
Sabatino JJ Jr, Shires J, Altman JD, Ford ML, Evavold BD. Loss of IFN-gamma enables the expansion of autoreactive CD4+ T cells to induce experimental autoimmune encephalomyelitis by a nonencephalitogenic myelin variant antigen. J. Immunol. 180: 4451-4457 (2008). *
Sabel MS, Arora A, Su G, Mathiowitz E, Reineke JJ, Chang AE. Synergistic effect of intratumoral IL-12 and TNF-alpha microspheres: systemic anti-tumor immunity is mediated by both CD8+ CTL and NK cells. Surgery 142: 749-760 (2007). *
Sadegh-Nasseri S, Dalai SK, Korb Ferris LC, Mirshahidi S. Suboptimal engagement of the T-cell receptor by a variety of peptide-MHC ligands triggers T-cell anergy. Immunology 129: 1-7 (2010). *
Sadegh-Nasseri S, Natarajan S, Chou CL, Hartman IZ, Narayan K, Kim A. Conformational heterogeneity of MHC class II: induced upon binding to different peptides is a key regulator in antigen presentation and epitope selection. Immunol. Res. Jan 12 [Epub ahead of print] (2010). *
Sadelain M, Brentjens R, Riviere I. The promise and potential pitfalls of chimeric antigen receptors. Curr. Opin. Immunol. 21: 215-223 (2009).
Saeki R, Ogino H, Kaneko S, Unoura M, Kobayashi K. Effects of chenodeoxycholic and ursodeoxycholic acids on interferon-gamma production by peripheral blood mononuclear cells from patients with primary biliary cirrhosis. J. Gastroenterol. 30: 739-744 (1995).
Sagoo GS, Tazi-Ahnini R, Barker JW, Elder JT, Nair RP, Samuelsson L, Traupe H, Trembath RC, Robinson DA, Iles MM. Meta-analysis of genome-wide studies of psoriasis susceptibility reveals linkage to chromosomes 6p21 and 4q28-q31 in Caucasian and Chinese Hans population. J. Invest. Dermatol. 122: 1401-1405 (2004). *
Saha A, Chatterjee SK, Foon KA, Bhattacharya-Chatterjee M. Anti-idiotype antibody induced cellular immunity in mice transgenic for human carcinoembryonic antigen. Immunology 118: 483-496 (2006). *
Saikali P, Antel JP, Newcombe J, Chen Z, Freedman M, Blain M, Cayrol R, Prat A, Hall JA, Arbour N. NKG2D-mediated cytotoxicity toward oligodendrocytes suggests a mechanism for tissue injury in multiple sclerosis. J. Neurosci. 27: 1220-1228 (2007).
Saitakis M, Dellaporta A, Gizeli E. Measurement of two-dimensional binding constants between cell-bound major histocompatibility complex and immobilized antibodies with an acoustic biosensor. Biophys. J. 95: 4963-4971 (2008). *
Saito Y, Yanagawa Y, Kikuchi K, Iijima N, Iwabuchi K, Onoe K. Low-dose lipopolysaccharide modifies the production of IL-12 by dendritic cells in response to various cytokines. J. Clin. Exp. Hematop. 46: 31-36 (2006).
Saitoh T, Fujiwara M, Nomoto M, Makino M, Watanabe H, Ishihara K, Kamimura T, Ichida F. Hepatic lesions induced by graft-versus-host reaction across MHC class II antigens: an implication for animal model of primary biliary cirrhosis. Clin. Immunol. Immunopathol. 49: 166-172 (1988).
Salam MA, Matsumoto N, Matin K, Tsuha Y, Nakao R, Hanada N, Senpuku H. Establishment of an animal model using recombinant NOD.B10.D2 mice to study initial adhesion of oral Streptococci. Clin. Diagn. Lab. Immunol. 11: 379-386 (2004). *
Salazar LM, Bermudez A, Patarroyo ME. HLA-DR allele reading register shifting is associated with immunity induced by SERA peptide analogues. Biochem. Biophys. Res. Commun. 372: 114-120 (2008). *
Saleki K, Hartigan N, Lith M, Bulleid N, Benham AM. Differential oxidation of HLA-B2704 and HLA-B2705 in lymphoblastoid and transfected adherent cells. Antioxid. Redox Signal. 8: 292-299 (2006).
Salem ML, Diaz-Montero CM, El-Naggar SA, Chen Y, Moussa O, Cole DJ. The TLR3 agonist poly(I:C) targets CD8+ T cells and augments their antigen-specific responses upon their adoptive transfer into naive recipient mice. Vaccine 27: 549-557 (2009). *
Salmaso C, Olive D, Pesce G, Bagnasco M. Costimulatory molecules and autoimmune thyroid diseases. Autoimmunity 35: 159-167 (2002).
Salomon J, Flower DR. Predicting class II MHC-peptide binding: a kernel based approach using similarity scores. BMC Bioinformatics 7: 501 (2006). *
Salomon P, Pizzimenti A, Panja A, Reisman A, Mayer L. The expression and regulation of class II antigens in normal and inflammatory bowel disease peripheral blood monocytes and intestinal epithelium. Autoimmunity 9: 141-149 (1991).
Salvarani C, Boiardi L, Mantovani V, Olivieri I, Ciancio G, Cantini F, Salvi F, Malatesta R, Molinotti C, Govoni M, Trotta F, Filippini D, Paolazzi G, Viggiani M. Association of MICA alleles and HLA-B51 in Italian patients with Behcet's disease. J. Rheumatol. 28: 1867-1870 (2001).
Samaroo D, Dickerson F, Kasarda DD, Green PH, Briani C, Yolken RH, Alaedini A. Novel immune response to gluten in individuals with schizophrenia. Schizophr. Res. Sep 10 [Epub ahead of print] (2009).
Samoilova EB, Horton JL, Hilliard B, Liu TS, Chen Y. IL-6-deficient mice are resistant to experimental autoimmune encephalomyelitis: roles of IL-6 in the activation and differentiation of autoreactive T cells. J. Immunol. 161: 6480-6486 (1998). *
Sanchez E, Torres B, Vilches JR, Lopez-Nevot MA, Ortego-Centeno N, Jimenez-Alonso J, Gonzalez-Gay MA, Ramon ED, Sanchez-Roman J, Nunez-Roldan A, Martin J, Gonzalez-Escribano MF. No primary association of MICA polymorphism with systemic lupus erythematosus. Rheumatology (Oxford) 45: 1096-1100 (2006). *
Sanchez FO, Linga Reddy MV, Mallbris L, Sakuraba K, Stahle M, Alarcon-Riquelme ME. IFN-regulatory factor 5 gene variants interact with the class I MHC locus in the Swedish psoriasis population. J. Invest. Dermatol. 128: 1704-1709 (2008). *
Sanchez Hell�n V, Gutierrez Rodero F. Toxicogenetics of antiretroviral treatment (II): neurotoxicity, hepatotoxicity, lactic acidosis, kidney damage, and other adverse effects of antiretroviral drugs. Enferm. Infecc. Microbiol. Clin. 26 Suppl. 6: 24-33 (2008).
Sanchez-Fueyo A, Domenig CM, Mariat C, Alexopoulos S, Zheng XX, Strom TB. Influence of direct and indirect allorecognition pathways on CD4(+)CD25(+) regulatory T-cell function in transplantation. Transpl. Int. 20: 534-541 (2007). *
Sanchez-Ruiz M, Wilden L, Muller W, Stenzel W, Brunn A, Miletic H, Schluter D, Deckert M. Molecular mimicry between neurons and an intracerebral pathogen induces a CD8 T cell-mediated autoimmune disease. J. Immunol. 180: 8421-8433 (2008). *
Sanda T, Iida S, Kayukawa S, Ueda R. Induction of class II major histocompatibility complex expression in human multiple myeloma cells by retinoid. Haematologica 92: 115-120 (2007). *
Sandalova T, Michaelsson J, Harris RA, Odeberg J, Schneider G, Karre K, Achour A. A structural basis for CD8+ T cell-dependent recognition of non-homologous peptide ligands: implications for molecular mimicry in autoreactivity. J. Biol. Chem. 280: 27069-27075 (2005). *
Sanderson IR. Dietary modulation of GALT. J. Nutr. 137: 2557S-2562S (2007). *
Sanderson IR, Croft NM. The anti-inflammatory effects of enteral nutrition. JPEN J. Parenter. Enteral Nutr. 29: S134-S140 (2005). *
Sanderson IR, Walker WA. The role of TLRs/Nods in intestinal development and homeostasis. Am. J. Physiol. Gastrointest. Liver Physiol. 292: G6-G10 (2007). *
Sandilands GP, McCrae J, Hill K, Perry M, Baxter D. Major histocompatibility complex class II (DR) antigen and costimulatory molecules on in vitro and in vivo activated human polymorphonuclear neutrophils. Immunology 119: 562-571 (2006). *
Sandner SE, Clarkson MR, Salama AD, Sanchez-Fueyo A, Domenig C, Habicht A, Najafian N, Yagita H, Azuma M, Turka LA, Sayegh MH. Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo. J. Immunol. 174: 3408-3415 (2005). *
Sandor N, Pap D, Prechl J, Erdei A, Bajtay Z. A novel, complement-mediated way to enhance the interplay between macrophages, dendritic cells and T lymphocytes. Mol. Immunol. 47: 438-448 (2009). *
Sanjeevi CB. Genes influencing innate and acquired immunity in type 1 diabetes and latent autoimmune diabetes in adults. Ann. N. Y. Acad. Sci. 1079: 67-80 (2006). *
Sanjeevi CB, Kanungo A, Berzina L, Shtauvere-Brameus A, Ghaderi M, Samal KC. MHC class I chain-related gene A alleles distinguish malnutrition-modulated diabetes, insulin-dependent diabetes, and non-insulin- dependent diabetes mellitus patients from eastern India. Ann. N. Y. Acad. Sci. 958: 341-344 (2002). *
Sanjeevi CB, Kanungo A, Samal KC. Immunogenetic studies on malnutrition-modulated diabetes mellitus. Ann. N. Y. Acad. Sci. 958: 144-147 (2002). *
Santamaria P. Autoimmune disease: genetics. ENCYCLOPEDIA OF LIFE SCIENCES Nature Publishing Group www.els.net (2001). *
Santamaria P. Genetic and therapeutic control of diabetogenic CD8+ T cells. Novartis Found. Symp. 292: 130-136 (2008).
Santiago JL, Li W, Lee A, Martinez A, Chandrasekaran A, Fernandez-Arquero M, Khalili H, de la Concha EG, Urcelay E, Gregersen PK. Localization of type 1 diabetes susceptibility in the ancestral haplotype 18.2 by high density SNP mapping. Genomics 94: 228-232 (2009). *
Santin I, Castellanos-Rubio A, Aransay AM, Gutierrez G, Gaztambide S, Rica I, Vicario JL, Noble JA, Castano L, Bilbao JR. Exploring the diabetogenicity of the HLA-B18-DR3 CEH: independent association with T1D genetic risk close to HLA-DOA. Genes Immun. 10: 596-600 (2009).
Santomasso BD, Roberts WK, Thomas A, Williams T, Blachere NE, Dudley ME, Houghton AN, Posner JB, Darnell RB. A T cell receptor associated with naturally occurring human tumor immunity. Proc. Natl. Acad. Sci. U.S.A. 104: 19073-19078 (2007). *
Santomasso BD, Roberts WK, Thomas A, Williams T, Blachere NE, Dudley ME, Houghton AN, Posner JB, Darnell RB. A T cell receptor associated with naturally occurring human tumor immunity. Proc. Natl. Acad. Sci. U.S.A. 104: 19073-19078 (2007). *
Santos FP, Bastos E, Ligeiro D, Mourao AF, Chaves R, Trindade H, Guedes-Pinto H, Branco JC. Genetic basis of ankylosing spondylitis. Acta Reumatol. Port. 32: 243-252 (2007).
Santos PS, Fust G, Prohaszka Z, Volz A, Horton R, Miretti M, Yu CY, Beck S, Uchanska-Ziegler B, Ziegler A. Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex. Genet. Test. 12: 481-486 (2008).
Santos SG, Lynch S, Campbell EC, Antoniou AN, Powis SJ. Induction of HLA-B27 heavy chain homodimer formation after activation in dendritic cells. Arthritis Res. Ther. 10: R100 (2008). *
Santucci F, Ibrahim KM, Bruzzone A, Hewit GM. Selection on MHC-linked microsatellite loci in sheep populations. Heredity 99: 340-348 (2007). *
Sapp H, Ithamukkala S, Brien TP, Ayata G, Shaz B, Dorfman DM, Wang HH, Antonioli DA, Farraye FA, Odze RD. The terminal ileum is affected in patients with lymphocytic or collagenous colitis. Am. J. Surg. Pathol. 26: 1484-1492 (2002).
Sarafana S, Coelho R, Neves A, Costa Trindade J. Gestational immunology. Acta Med. Port. 20: 355-358 (2008).
Sarafova SD, Van Laethem F, Adoro S, Guinter T, Sharrow SO, Feigenbaum L, Singer A. Upregulation of CD4 expression during MHC class II-specific positive selection is essential for error-free lineage choice. Immunity 31: 480-490 (2009). *
Sarantopoulos S, Lu L, Cantor H. Qa-1 restriction of CD8(+) suppressor T cells. J. Clin. Invest. 114: 1218-1221 (2004). *
Sarkar S, Fox DA. Dendritic cells in rheumatoid arthritis. Front. Biosci. 10: 656-665 (2005).
Saruhan-Direskeneli G. Shared epitope homozygosity' is strongly associated with rheumatoid arthritis in Turkey. Istanbul Rheumatology Study Group. Br. J. Rheumatol. 37: 1126-1128 (1998). *
Saruhan-Direskeneli G, Uyar FA, Bas F, Gunoz H, Bundak R, Saka N, Darendeliler F. HLA-DR and -DQ associations with insulin-dependent diabetes mellitus in a population of Turkey. Hum. Immunol. 61: 296-302 (2000).
Sasaki M, Nakanuma Y. Frequent expression of MUC1 apomucin on biliary epithelial cells of damaged small bile ducts in primary biliary cirrhosis and chronic viral hepatitis: an immunohistochemical study. Hepatology 23: 1313-1317 (1996). *
Sato H, Lagan AL, Alexopoulou C, Vassilakis DA, Ahmad T, Pantelidis P, Veeraraghavan S, Renzoni E, Denton C, Black C, Wells AU, Du Bois RM, Welsh KI. The TNF-863A allele strongly associates with anticentromere antibody positivity in scleroderma. Arthritis Rheum. 50: 558-564 (2004). *
Sato K, Sato U, Tateishi S, Kubo K, Horikawa R, Mimura T, Yamamoto K, Kanda H. Aire downregulates multiple molecules that have contradicting immune-enhancing and immune-suppressive functions. Biochem. Biophys. Res. Commun. 318: 935-940 (2004). *
Sato-Takeda M, Takasaki I, Takeda K, Sasaki A, Andoh T, Nojima H, Shiraki K, Kuraishi Y, Hanaoka K, Tokunaga K, Yabe T. Major histocompatibility complex haplotype is associated with postherpetic pain in mice. Anesthesiology 104: 1063-1069 (2006).
Satsangi J. Genetics of inflammatory bowel disease: from bench to bedside? Acta Odontol. Scand. 59: 187-192 (2001). *
Satsangi J, Parkes M, Jewell DP, Bell JI. Genetics of inflammatory bowel disease. Clin. Sci. (Lond.) 94: 473-478 (1998). *
Satsangi J, Welsh KI, Bunce M, Julier C, Farrant JM, Bell JI, Jewell DP. Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet 347: 1212-1217 (1996).
Saubermann LJ, Beck P, De Jong YP, Pitman RS, Ryan MS, Kim HS, Exley M, Snapper S, Balk SP, Hagen SJ, Kanauchi O, Motoki K, Sakai T, Terhorst C, Koezuka Y, Podolsky DK, Blumberg RS. Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice. Gastroenterology 119: 119-128 (2000). *
Sauermann U, Siddiqui R, Suh YS, Platzer M, Leuchte N, Meyer H, Matz-Rensing K, Stoiber H, Nurnberg P, Hunsmann G, Stahl-Hennig C, Krawczak M. MHC class I haplotypes associated with survival time in simian immunodeficiency virus (SIV)-infected rhesus macaques. Genes Immun. 9: 69-80 (2008). *
Savage P, Dyson J, Milrain M, Mathews D, King B, Chan HT, Barber L, Epenetos A, Ogg G, McMichael A, Glennie MJ, French RR. Immunotherapy with antibody-targeted HLA class I complexes: results of in vivo tumour cell killing and therapeutic vaccination. Tumour Biol. 28: 205-211 (2007).
Sawa SI, Kamimura D, Jin GH, Morikawa H, Kamon H, Nishihara M, Ishihara K, Murakami M, Hirano T. Autoimmune arthritis associated with mutated interleukin (IL)-6 receptor gp130 is driven by STAT3/IL-7-dependent homeostatic proliferation of CD4+ T cells. J. Exp. Med. 203: 1459-1470 (2006). *
Sawai H, Go Y, Satta Y. Biological implication for loss of function at major histocompatibility complex loci. Immunogenetics 60: 295-302 (2008). *
Sawcer S, Ban M, Maranian M, Yeo TW, Compston A, Kirby A, Daly MJ, De Jager PL, Walsh E, Lander ES, Rioux JD, Hafler DA, Ivinson A, Rimmler J, Gregory SG, Schmidt S, Pericak-Vance MA, Akesson E, Hillert J, Datta P, Oturai A, Ryder LP, Harbo HF, et al. A high-density screen for linkage in multiple sclerosis. Am. J. Hum. Genet. 77: 454-467 (2005). *
Sawcer S, Jones HB, Feakes R, Gray J, Smaldon N, Chataway J, Robertson N, Clayton D, Goodfellow PN, Compston A. A genome screen in multiple sclerosis reveals susceptibility loci on chromosome 6p21 and 17q22. Nat. Genet. 13: 464-468 (1996). *
Saxena K, Kitzmiller KJ, Wu YL, Zhou B, Esack N, Hiremath L, Chung EK, Yang Y, Yu CY. Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: a comparison of Asian-Indian and European American populations. Mol. Immunol. 46: 1289-1303 (2009). *
Saxena V, Ondr JK, Magnusen AF, Munn DH, Katz JD. The countervailing actions of myeloid and plasmacytoid dendritic cells control autoimmune diabetes in the nonobese diabetic mouse. J. Immunol. 179: 5041-5053 (2007). *
Scarisbrick IA, Rodriguez M. Hit-Hit and Hit-Run: viruses in the playing field of multiple sclerosis. Curr. Neurol. Neurosci. Rep. 3: 265-271 (2003).
Schaffer FM, Palermos J, Zhu ZB, Barger BO, Cooper MD, Volanakis JE. Individuals with IgA deficiency and common variable immunodeficiency share polymorphisms of major histocompatibility complex class III genes. Proc. Natl. Acad. Sci. U.S.A. 86: 8015-8019 (1989). *
Schamel WW, Risueno RM, Minguet S, Ortiz AR, Alarcon B. A conformation- and avidity-based proofreading mechanism for the TCR-CD3 complex. Trends Immunol. 27: 176-182 (2006). *
Schaschl H, Wandeler P, Suchentrunk F, Obexer-Ruff G, Goodman SJ. Selection and recombination drive the evolution of MHC class II DRB diversity in ungulates. Heredity 97: 427-437 (2006). *
Schepis D, D'Amato M, Studahl M, Bergstrom T, Karre K, Berg L. Herpes simplex virus infection downmodulates NKG2D ligand expression. Scand. J. Immunol. 69: 429-436 (2009). *
Schermann C, Fischer G, Witt V, Kurz M, Potschger U, Fritsch G. Detection of human cytomegalovirus-specific T lymphocytes in human blood: comparison of two methods. Cytotherapy 10: 834-841 (2008).
Schjetne KW, Thompson KM, Aarvak T, Fleckenstein B, Sollid LM, Bogen B. A mouse C kappa-specific T cell clone indicates that DC-SIGN is an efficient target for antibody-mediated delivery of T cell epitopes for MHC class II presentation. Int. Immunol. 14: 1423-1430 (2002). *
Schlosser E, Mueller M, Fischer S, Basta S, Busch DH, Gander B, Groettrup M. TLR ligands and antigen need to be coencapsulated into the same biodegradable microsphere for the generation of potent cytotoxic T lymphocyte responses. Vaccine 26: 1626-1637 (2008). *
Schlosser E, Otero C, Wuensch C, Kessler B, Edelmann M, Brunisholz R, Drexler I, Legler DF, Groettrup M. A novel cytosolic class I antigen-processing pathway for endoplasmic-reticulum-targeted proteins. EMBO Rep. 8: 945-951 (2007). *
Schmid D, Dengjel J, Schoor O, Stevanovic S, Munz C. Autophagy in innate and adaptive immunity against intracellular pathogens. J. Mol. Med. 84: 194-202 (2006). *
Schmid D, Munz C. Immune surveillance via self digestion. Autophagy 3: 133-135 (2007). *
Schmid D, Pypaert M, Munz C. Antigen-loading compartments for major histocompatibility complex class II molecules continuously receive input from autophagosomes. Immunity 26: 79-92 (2007). *
Schmitt-Egenolf M, Windemuth C, Hennies HC, Albis-Camps M, von Engelhardt B, Wienker T, Reis A, Traupe H, Blasczyk R. Comparative association analysis reveals that corneodesmosin is more closely associated with psoriasis than HLA-Cw*0602-B*5701 in German families. Tissue Antigens 57: 440-446 (2001). *
Scholz C, Tampe R. The intracellular antigen transport machinery TAP in adaptive immunity and virus escape mechanisms. J. Bioenerg. Biomembr. 37: 509-515 (2005). *
Scholzen A, Mittag D, Rogerson SJ, Cooke BM, Plebanski M. Plasmodium falciparum-mediated induction of human CD25Foxp3 CD4 T cells is independent of direct TCR stimulation and requires IL-2, IL-10 and TGFbeta. PLoS. Pathog. 5: e1000543 (2009). *
Schonbach C, Koh JL, Flower DR, Brusic V. An update on the Functional Molecular Immunology (FIMM) database. Appl. Bioinformatics 4: 25-31 (2005).
SchonefuB A, Wendt W, Schattling B, Schulten R, Hoffmann K, Stuecker M, Tigges C, Lubbert H, Stichel C. Upregulation of cathepsin S in psoriatic keratinocytes. Exp. Dermatol. Oct 22 [Epub ahead of print] (2009).
Schott E, Bonasio R, Ploegh HL. Elimination in vivo of developing T cells by natural killer cells. J. Exp. Med. 198: 1213-1224 (2003). *
Schou TW, Permin A, Juul-Madsen HR, Sorensen P, Labouriau R, Nguyen TL, Fink M, Pham SL. Gastrointestinal helminths in indigenous and exotic chickens in Vietnam: association of the intensity of infection with the major histocompatibility complex. Parasitology 134: 561-573 (2007). *
Schrambach S, Ardizzone M, Leymarie V, Sibilia J, Bahram S. In vivo expression pattern of MICA and MICB and its relevance to auto-immunity and cancer. PLoS ONE 2: e518 (2007). *
Schreuder GM, Hurley CK, Marsh SG, Lau M, Fernandez-Vina M, Noreen HJ, Setterholm M, Maiers M. The HLA Dictionary 2004: a summary of HLA-A, -B, -C, -DRB1/3/4/5 and -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Tissue Antigens 65: 1-55 (2005). *
Schreuder GM, Hurley CK, Marsh SG, Lau M, Maiers M, Kollman C, Noreen HJ. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Tissue Antigens 58: 109-140 (2001). *
Schreuder GM, Hurley CK, Marsh SG, Lau M, Maiers M, Kollman C, Noreen HJ. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5 and -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR and -DQ antigens. Eur. J. Immunogenet. 28: 565-596 (2001). *
Schreuder GM, Hurley CK, Marsh SG, Lau M, Maiers M, Kollman C, Noreen HJ. The HLA dictionary 2001: a summary of HLA-A, -B, -C, -DRB1/3/4/5, -DQB1 alleles and their association with serologically defined HLA-A, -B, -C, -DR, and -DQ antigens. Hum. Immunol. 62: 826-849 (2001).
Schrodt S, Koch J, Tampe R. Membrane topology of the transporter associated with antigen processing (TAP1) within an assembled functional peptide-loading complex. J. Biol. Chem. 281: 6455-6462 (2006). *
Schroeder HW Jr, Zhu ZB, March RE, Campbell RD, Berney SM, Nedospasov SA, Turetskaya RL, Atkinson TP, Go RC, Cooper MD, Volanakis JE. Susceptibility locus for IgA deficiency and common variable immunodeficiency in the HLA-DR3, -B8, -A1 haplotypes. Mol. Med. 4: 72-86 (1998). *
Schrumpf E, Boberg KM. PSC and IBD - when and how do they relate to each other? Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper�s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 77. October 15-16 (2003). *
Schubert MS. Allergic fungal sinusitis. Clin. Rev. Allergy Immunol. 30: 205-216 (2006).
Schultz H. From infection to autoimmunity: a new model for induction of ANCA against the bactericidal/permeability increasing protein (BPI). Autoimmun. Rev. 6: 223-227 (2007).
Schultz H, Hume J, Zhang de S, Gioannini TL, Weiss JP. A novel role for the bactericidal/permeability increasing protein in interactions of Gram-negative bacterial outer membrane blebs with dendritic cells. J. Immunol. 179: 2477-2484 (2007). *
Schultz H, Schinke S, Weiss J, Cerundolo V, Gross WL, Gadola S. BPI-ANCA in transporter associated with antigen presentation (TAP) deficiency: possible role in susceptibility to Gram-negative bacterial infections. Clin. Exp. Immunol. 133: 252-259 (2003). *
Schurmann M. Genetics of sarcoidosis. Semin. Respir. Crit. Care Med. 24: 213-222 (2003).
Schurmann M, Lympany PA, Reichel P, Muller-Myhsok B, Wurm K, Schlaak M, Muller-Quernheim J, du Bois RM, Schwinger E. Familial sarcoidosis is linked to the major histocompatibility complex region. Am. J. Respir. Crit. Care Med. 162: 861-864 (2000). *
Schurr E, Alcais A, Singh M, Mehra N, Abel L. Mycobacterial infections: PARK2 and PACRG associations in leprosy. Tissue Antigens 69 Suppl. 1: 231-233 (2007). *
Schuurhuis DH, Lesterhuis WJ, Kramer M, Looman MG, van Hout-Kuijer M, Schreibelt G, Boullart AC, Aarntzen EH, Benitez-Ribas D, Figdor CG, Punt CJ, de Vries IJ, Adema GJ. Polyinosinic polycytidylic acid prevents efficient antigen expression after mRNA electroporation of clinical grade dendritic cells. Cancer Immunol. Immunother. 58: 1109-1115 (2009). *
Schweitzer SC, Reding AM, Patton HM, Sullivan TP, Stubbs CE, Villalobos-Menuey E, Huber SA, Newell MK. Endogenous versus exogenous fatty acid availability affects lysosomal acidity and MHC class II expression. J. Lipid Res. 47: 2525-2537 (2006). *
Schwensow N, Fietz J, Dausmann KH, Sommer S. Neutral versus adaptive genetic variation in parasite resistance: importance of major histocompatibility complex supertypes in a free-ranging primate. Heredity 99: 265-277 (2007). *
Scola L, Lio D, Candore G, Forte GI, Crivello A, Colonna-Romano G, Pes MG, Carru C, Ferrucci L, Deiana L, Baggio G, Franceschi C, Caruso C. Analysis of HLA-DRB1,DQA1,DQB1 haplotypes in Sardinian centenarians. Exp. Gerontol. 43: 114-118 (2008).
Scott-Taylor TH, Green MR, Raeiszadeh M, Workman S, Webster AD. Defective maturation of dendritic cells in common variable immunodeficiency. Clin. Exp. Immunol. 145: 420-427 (2006). *
Scrivo R, Di Franco M, Spadaro A, Valesini G. The immunology of rheumatoid arthritis. Ann. N. Y. Acad. Sci. 1108: 312-322 (2007). *
Seach N, Ueno T, Fletcher AL, Lowen T, Mattesich M, Engwerda CR, Scott HS, Ware CF, Chidgey AP, Gray DH, Boyd RL. The lymphotoxin pathway regulates Aire-independent expression of ectopic genes and chemokines in thymic stromal cells. J. Immunol. 180: 5384-5392 (2008). *
Seddon JM, Berggren KT, Fleeman LM. Evolutionary history of DLA class II haplotypes in canine diabetes mellitus through single nucleotide polymorphism genotyping. Tissue Antigens Dec 30 [Epub ahead of print] (2009). *
Seewaldt S, Thomas HE, Ejrnaes M, Christen U, Wolfe T, Rodrigo E, Coon B, Michelsen B, Kay TW, von Herrath MG. Virus-induced autoimmune diabetes: most beta-cells die through inflammatory cytokines and not perforin from autoreactive (anti-viral) cytotoxic T-lymphocytes. Diabetes 49: 1801-1909 (2000). *
Segal BM. The role of natural killer cells in curbing neuroinflammation. J. Neuroimmunol. 191: 2-7 (2007).
Segu�n-Estevez Q, De Palma R, Krawczyk M, Leimgruber E, Villard J, Picard C, Tagliamacco A, Abbate G, Gorski J, Nocera A, Reith W. The transcription factor RFX protects MHC class II genes against epigenetic silencing by DNA methylation. J. Immunol. 183: 2545-2553 (2009).
Segura E, Albiston AL, Wicks IP, Chai SY, Villadangos JA. Different cross-presentation pathways in steady-state and inflammatory dendritic cells. Proc. Natl. Acad. Sci. U.S.A. 106: 20377-20381 (2009). *
Seifert U, Maranon C, Shmueli A, Desoutter JF, Wesoloski L, Janek K, Henklein P, Diescher S, Andrieu M, de la Salle H, Weinschenk T, Schild H, Laderach D, Galy A, Haas G, Kloetzel PM, Reiss Y, Hosmalin A. An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope. Nat. Immunol. 4: 375-379 (2003). *
Seiler M, Brabcova I, Viklicky O, Hribova P, Rosenberger C, Pratschke J, Lodererova A, Matz M, Schonemann C, Reinke P, Volk HD, Kotsch K. Heightened expression of the cytotoxicity receptor NKG2D correlates with acute and chronic nephropathy after kidney transplantation. Am. J. Transplant. 7: 423-433 (2007). *
Seitzer U, Gerdes J, Muller-Quernheim J. Genotyping in the MHC locus: potential for defining predictive markers in sarcoidosis. Respir. Res. 3: 6 (2002). *
Seki SS, Sugimura K, Ota M, Matsuzawa J, Katsuyama Y, Ishizuka K, Mochizuki T, Suzuki K, Yoneyama O, Mizuki N, Honma T, Inoko H, Asakura H. Stratification analysis of MICA triplet repeat polymorphisms and HLA antigens associated with ulcerative colitis in Japanese. Tissue Antigens 58: 71-76 (2001). *
Sekine H, Ferreira RC, Pan-Hammarstrom Q, Graham RR, Ziemba B, de Vries SS, Liu J, Hippen K, Koeuth T, Ortmann W, Iwahori A, Elliott MK, Offer S, Skon C, Du L, Novitzke J, Lee AT, Zhao N, Tompkins JD, Altshuler D, Gregersen PK, et al. Role for Msh5 in the regulation of Ig class switch recombination. Proc. Natl. Acad. Sci. U.S.A. 104: 7193-7198 (2007). *
Sekine H, Graham KL, Zhao S, Elliott MK, Ruiz P, Utz PJ, Gilkeson GS. Role of MHC-linked genes in autoantigen selection and renal disease in a murine model of systemic lupus erythematosus. J. Immunol. 177: 7423-7434 (2006). *
Sela U, Sharabi A, Dayan M, Hershkoviz R, Mozes E. The role of dendritic cells in the mechanism of action of a peptide that ameliorates lupus in murine models. Immunology 128: e395-e405 (2009). *
Seldin MF, Amos CI. Shared susceptibility variations in autoimmune diseases: a brief perspective on common issues. Genes Immun. 10: 1-4 (2009). *
Seliger B. Strategies of tumor immune evasion. BioDrugs 19: 347-354 (2005).
Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A. Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity. J. Immunol. Jan 20 [Epub ahead of print] (2010).
Selmi C. Environmental factors in primary biliary cirrhosis. Hepatol. Res. 37 Suppl. 3: S370-S376 (2007). *
Selmi C, Ichiki Y, Invernizzi P, Podda M, Gershwin ME. The enigma of primary biliary cirrhosis. Clin. Rev. Allergy Immunol. 28: 73-82 (2005). *
Selmi C, Invernizzi P, Zuin M, Podda M, Seldin MF, Gershwin ME. Genes and (auto)immunity in primary biliary cirrhosis. Genes Immun. 6: 543-556 (2005). *
Selmi C, Zuin M, Gershwin ME. The unfinished business of primary biliary cirrhosis. J. Hepatol. 49: 451-460 (2008). *
Semana G, Allanic H, Quillivic F, Vallejo MT, Simon JP, Genetet B, Fauchet R. Implication of the HLA-DRB3 gene in Graves' disease: predominance of allele Dw24. Hum. Immunol. 29: 143-149 (1990).
Semkova K, Black M. Pemphigoid gestationis: current insights into pathogenesis and treatment. Eur. J. Obstet. Gynecol. Reprod. Biol. 145: 138-144 (2009).
Semple JI, Ribas G, Hillyard G, Brown SE, Sanderson CM, Campbell RD. A novel gene encoding a coiled-coil mitochondrial protein located at the telomeric end of the human MHC class III region. Gene 314: 41-54 (2003). *
Seppanen M, Lokki ML, Notkola IL, Mattila K, Valtonen V, Nieminen A, Vesanen M, Asikainen S, Meri S. Complement and C4 null alleles in severe chronic adult periodontitis. Scand. J. Immunol. 65: 176-181 (2007). *
Sercarz EE, Maverakis E. Mhc-guided processing: binding of large antigen fragments. Nat. Rev. Immunol. 3: 621-629 (2003). *
Serfaty L, Poupon R. Ursodeoxycholic acid and colorectal carcinogenesis. Falk Symposium 141. XVIII International Bile Acid Meeting: Bile Acid Biology and its Therapeutic Implications. Stockholm (Sweden). p. 76-77. June 18-19 (2004). *
Serrano NC, Millan P, Paez MC. Non-HLA associations with autoimmune diseases. Autoimmun. Rev. 5: 209-214 (2006).
Serrano-Martin MM, Moreno-Perez D, Garcia-Martin FJ, Jurado-Ortiz A. Major histocompatibility complex class II deficiency. An. Pediatr. (Barc.) 66: 305-308 (2007).
Serreze D, Marron M, Dilorenzo T. "Humanized" HLA transgenic NOD mice to identify pancreatic beta cell autoantigens of potential clinical relevance to type 1 diabetes. Ann. N. Y. Acad. Sci. 1103: 103-111 (2007). *
Serreze DV, Niens M, Kulik J, Dilorenzo TP. Bridging mice to men: using HLA transgenic mice to enhance the future prediction and prevention of autoimmune type 1 diabetes in humans. Methods Mol. Biol. 602: 119-134 (2010). *
Sers C, Kuner R, Falk CS, Lund P, Sueltmann H, Braun M, Buness A, Ruschhaupt M, Conrad J, Mang-Fatehi S, Stelniec I, Krapfenbauer U, Poustka A, Sch�fer R. Down-regulation of HLA class I and NKG2D ligands through a concerted action of MAPK and DNA methyltransferases in colorectal cancer cells. Int. J. Cancer 125: 1626-1639 (2009). *
Sester M, Koebernick K, Owen D, Ao M, Bromberg Y, May E, Stock E, Andrews L, Groh V, Spies T, Steinle A, Menz B, Burgert HG. Conserved amino acids within the adenovirus 2 E3/19K protein differentially affect downregulation of MHC class I and MICA/B proteins. J. Immunol. 184: 255-267 (2010).
Setty M, Hormaza L, Guandalini S. Celiac disease: risk assessment, diagnosis, and monitoring. Mol. Diagn. Ther. 12: 289-298 (2008).
Seydel F, Garrigan E, Stutevoss B, Belkin N, Makadia B, Carter J, Shi JD, Davoodi-Semiromi A, McDuffie M, Litherland SA. GM-CSF induces STAT5 binding at epigenetic regulatory sites within the Csf2 promoter of non-obese diabetic (NOD) mouse myeloid cells. J. Autoimmun. 31: 377-384 (2008).
Sgarbi JA, Maciel RM. Pathogenesis of autoimmune thyroid diseases. Arq. Bras. Endocrinol. Metabol. 53: 5-14 (2009).
Shaikh SR, Edidin M. Polyunsaturated fatty acids, membrane organization, T cells, and antigen presentation. Am. J. Clin. Nutr. 84: 1277-1289 (2006). *
Shaikh SR, Rockett BD, Salameh M, Carraway K. Docosahexaenoic acid modifies the clustering and size of lipid rafts and the lateral organization and surface expression of MHC class I of EL4 cells. J. Nutr. 139: 1632-1639 (2009). *
Shalev I, Liu H, Koscik C, Bartczak A, Javadi M, Wong KM, Maknojia A, He W, Liu MF, Diao J, Winter E, Manuel J, McCarthy D, Cattral M, Gommerman J, Clark DA, Phillips MJ, Gorczynski RR, Zhang L, Downey G, Grant D, Cybulsky MI, Levy G. Targeted deletion of fgl2 leads to impaired regulatory T cell activity and development of autoimmune glomerulonephritis. J. Immunol. 180: 249-260 (2008). *
Shankarkumar U, Ghosh K. MHC non-HLA gene polymorphisms in transplantation. Indian J. Pathol. Microbiol. 50: 881-885 (2007).
Shanker A, Buferne M, Schmitt-Verhulst AM. Cooperative action of CD8 T lymphocytes and natural killer cells controls tumour growth under conditions of restricted T-cell receptor diversity. Immunology 129: 41-54 (2010). *
Shao H, Kaplan HJ, Sun D. Major histocompatibility complex molecules on parenchymal cells of the target organ protect against autoimmune disease. Chem. Immunol. Allergy 92: 94-104 (2007).
Shao L, Kamalu O, Mayer L. Non-classical MHC class I molecules on intestinal epithelial cells: mediators of mucosal crosstalk. Immunol. Rev. 206: 160-176 (2005). *
Shao W, Lobashevsky ES, Kaslow RA, Dorak MT. MICA intron 1 sequences of conserved extended HLA haplotypes: implications for sequencing-based typing. Genes Immun. 5: 371-374 (2004). *
Sharifpanah F, Wartenberg M, Hannig M, Piper HM, Sauer H. Peroxisome proliferator-activated receptor alpha agonists enhance cardiomyogenesis of mouse ES cells by utilization of a reactive oxygen species-dependent mechanism. Stem Cells 26: 64-71 (2008). *
Sharma P, Shen Y, Wen S, Yamada S, Jungbluth AA, Gnjatic S, Bajorin DF, Reuter VE, Herr H, Old LJ, Sato E. CD8 tumor-infiltrating lymphocytes are predictive of survival in muscle-invasive urothelial carcinoma. Proc. Natl. Acad. Sci. U.S A. 104: 3967-3972 (2007). *
Sharma R, Li DZ. Role of dendritic cells in atherosclerosis. Asian Cardiovasc. Thorac. Ann. 14: 166-169 (2006).
Shastri N, Cardinaud S, Schwab SR, Serwold T, Kunisawa J. All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway. Immunol. Rev. 207: 31-41 (2005). *
Shaw BE, Maldonado H, Madrigal JA, Smith C, Petronzelli F, Mayor NP, Potter MN, Bodmer JG, Marsh SG. Polymorphisms in the TNFA gene promoter region show evidence of strong linkage disequilibrium with HLA and are associated with delayed neutrophil engraftment in unrelated donor hematopoietic stem cell transplantation. Tissue Antigens 63: 401-411 (2004). *
Shaw MA, Clayton D, Atkinson SE, Williams H, Miller N, Sibthorpe D, Blackwell JM. Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35. J. Med. Genet. 33: 672-677 (1996). *
Shaw MA, Donaldson IJ, Collins A, Peacock CS, Lins-Lainson Z, Shaw JJ, Ramos F, Silveira F, Blackwell JM. Association and linkage of leprosy phenotypes with HLA class II and tumour necrosis factor genes. Genes Immun. 2: 196-204 (2001). *
Shegarfi H, Sydnes K, Lovik M, Inngjerdingen M, Rolstad B, Naper C. The role of natural killer cells in resistance to the intracellular bacterium Listeria monocytogenes in rats. Scand. J. Immunol. 70: 238-244 (2009). *
Sheikh NA, Jones LA. CD54 is a surrogate marker of antigen presenting cell activation. Cancer Immunol. Immunother. 57: 1381-1390 (2008). *
Sheil JM, Frankenberry MA, Schell TD, Brundage KM, Barnett JB. Propanil exposure induces delayed but sustained abrogation of cell-mediated immunity through direct interference with cytotoxic T-lymphocyte effectors. Environ. Health Perspect. 114: 1059-1064 (2006). *
Shen LH, He B, Wang BY, Zeng JZ, Zhou L, Hu LH, Bu J, Wang L. Effect of retinoid X receptor activation on oxidized low-density lipoprotein induced cell differentiation of murine macrophage cell line into dendritic like cells. Zhonghua Xin Xue Guan Bing Za Zhi 35: 833-837 (2007).
Shen N, Tsao BP. Current advances in the human lupus genetics. Curr. Rheumatol. Rep. 6: 391-398 (2004).
Shen Z, Wang G, Fan JY, Li W, Liu YF. HLA DR B1*04, *07-restricted epitopes on Keratin 17 for autoreactive T cells in psoriasis. J. Dermatol. Sci. 38: 25-39 (2005).
Sheng KC, Pietersz GA, Tang CK, Ramsland PA, Apostolopoulos V. Reactive oxygen species level defines two functionally distinctive stages of inflammatory dendritic cell development from mouse bone marrow. J. Immunol. Feb 22 [Epub ahead of print] (2010).
Shetty AK, Gedalia A. Childhood sarcoidosis: a rare but fascinating disorder. Pediatr. Rheumatol. Online J. 6: 16 (2008). *
Shevach EM, Dipaolo RA, Andersson J, Zhao DM, Stephens GL, Thornton AM. The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells. Immunol. Rev. 212: 60-73 (2006). *
Shevach EM, Thornton A, Suri-Payer E. T lymphocyte-mediated control of autoimmunity. Novartis Found. Symp. 215: 200-211 (1998).
Shi FD, Piao WH, Kuo YP, Campagnolo DI, Vollmer TL, Lukas RJ. Nicotinic attenuation of central nervous system inflammation and autoimmunity. J. Immunol. 182: 1730-1739 (2009).
Shi L, Liu XM, Hu XY, Wang JS, Fang Q. The effect of lipopolysaccharide on the expression and activity of Toll-like receptor 4 in mesenchymal stem cells. Zhonghua Xue Ye Xue Za Zhi 28: 828-831 (2007).
Shi MQ, Wei GJ, Tabel H. Trypanosoma congolense infections: MHC class II-restricted immune responses mediate either protection or disease, depending on IL-10 function. Parasite Immunol. 29: 107-111 (2007). *
Shi Y, Kaliyaperumal A, Lu L, Southwood S, Sette A, Michaels MA, Datta SK. Promiscuous presentation and recognition of nucleosomal autoepitopes in lupus: role of autoimmune T cell receptor alpha chain. J. Exp. Med. 187: 367-378 (1998). *
Shichi D, Kikkawa EF, Ota M, Katsuyama Y, Kimura A, Matsumori A, Kulski JK, Naruse TK, Inoko H. The haplotype block, NFKBIL1-ATP6V1G2-BAT1-MICB-MICA, within the class III-class I boundary region of the human major histocompatibility complex may control susceptibility to hepatitis C virus-associated dilated cardiomyopathy. Tissue Antigens 66: 200-208 (2005). *
Shichi D, Ota M, Katsuyama Y, Inoko H, Naruse TK, Kimura A. Complex divergence at a microsatellite marker C1_2_5 in the lineage of HLA-Cw/-B haplotype. J. Hum. Genet. 54: 224-229 (2009).
Shigeru S, Akitoshi N, Subaru MH, Shiozaki A. The balance between cytotoxic NK cells and regulatory NK cells in human pregnancy. J. Reprod. Immunol. 77: 14-22 (2008).
Shih FF, Racz J, Allen PM. Differential MHC class II presentation of a pathogenic autoantigen during health and disease. J. Immunol. 176: 3438-3448 (2006). *
Shih SC, Lee YJ, Liu HF, Dang CW, Chang SC, Lin SC, Kao CR. Polymorphism in transmembrane region of MICA gene and cholelithiasis. World J. Gastroenterol. 9: 1541-1544 (2003). *
Shiina T, Inoko H, Kulski JK. An update of the HLA genomic region, locus information and disease associations: 2004. Tissue Antigens 64: 631-649 (2004). *
Shiina T, Ota M, Shimizu S, Katsuyama Y, Hashimoto N, Takasu M, Anzai T, Kulski JK, Kikkawa E, Naruse T, Kimura N, Yanagiya K, Watanabe A, Hosomichi K, Kohara S, Iwamoto C, Umehara Y, Meyer A, Wanner V, Sano K, Macquin C, Ikeo K, Tokunaga K, et al. Rapid evolution of MHC class I genes in primates generates new disease alleles in man via hitchhiking diversity. Genetics 173: 1555-1570 (2006). *
Shiina T, Tamiya G, Oka A, Yamagata T, Yamagata N, Kikkawa E, Goto K, Mizuki N, Watanabe K, Fukuzumi Y, Taguchi S, Sugawara C, Ono A, Chen L, Yamazaki M, Tashiro H, Ando A, Ikemura T, Kimura M, Inoko H. Nucleotide sequencing analysis of the 146-kilobase segment around the IkBL and MICA genes at the centromeric end of the HLA class I region. Genomics 47: 372-382 (1998). *
Shilyansky J, Jacobs P, Doffek K, Sugg SL. Induction of cytolytic T lymphocytes against pediatric solid tumors in vitro using autologous dendritic cells pulsed with necrotic primary tumor. J. Pediatr. Surg. 42: 54-61 (2007).
Shim HK, Musson JA, Harper HM, McNeill HV, Walker N, Flick-Smith H, von Delwig A, Williamson ED, Robinson JH. Mechanisms of major histocompatibility complex class II-restricted processing and presentation of the V antigen of Yersinia pestis. Immunology 119: 385-392 (2006). *
Shimamura M, Huang YY, Okamoto N, Suzuki N, Yasuoka J, Morita K, Nishiyama A, Amano Y, Mishina T. Modulation of Valpha19 NKT cell immune responses by alpha-mannosyl ceramide derivatives consisting of a series of modified sphingosines. Eur. J. Immunol. 37: 1836-1844 (2007). *
Shimizu M, Yuh K, Aoyama S, Ichihara I, Watanabe H, Shijo H, Okumura M. Immunohistochemical characterization of inflammatory infiltrates at the site of bile duct injury in primary biliary cirrhosis. Liver 6: 1-6 (1986).
Shimoda M, Koni PA. MHC-restricted B-cell antigen presentation in memory B-cell maintenance and differentiation. Crit. Rev. Immunol. 27: 47-60 (2007).
Shimoda M, Mmanywa F, Joshi SK, Li T, Miyake K, Pihkala J, Abbas JA, Koni PA. Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance. J. Immunol. 176: 6503-6511 (2006). *
Shimoda S, Nakamura M, Ishibashi H, Hayashida K, Niho Y. HLA DRB4 0101-restricted immunodominant T cell autoepitope of pyruvate dehydrogenase complex in primary biliary cirrhosis: evidence of molecular mimicry in human autoimmune diseases. J. Exp. Med. 181: 1835-1845 (1995). *
Shimomura Y, Ogawa A, Kawada M, Sugimoto K, Mizoguchi E, Shi HN, Pillai S, Bhan AK, Mizoguchi A. A unique B2 B cell subset in the intestine. J. Exp. Med. 205: 1343-1355 (2008). *
Shin HD, Yang SW, Kim DH, Park Y. Independent association of tumor necrosis factor polymorphism with type 1 diabetes susceptibility. Ann. N. Y. Acad. Sci. 1150: 76-85 (2008). *
Shin JS, Ebersold M, Pypaert M, Delamarre L, Hartley A, Mellman I. Surface expression of MHC class II in dendritic cells is controlled by regulated ubiquitination. Nature 444: 115-118 (2006). *
Shin S, El-Diwany R, Schaffert S, Adams EJ, Garcia KC, Pereira P, Chien YH. Antigen recognition determinants of gammadelta T cell receptors. Science 308: 252-255 (2005). *
Shingler WH, Chikoti P, Kingsman SM, Harrop R. Identification and functional validation of MHC class I epitopes in the tumor-associated antigen 5T4. Int. Immunol. 20: 1057-1066 (2008).
Shirasawa S. Susceptibility genes for the development of autoimmune thyroid disease. Nippon Rinsho 64: 2208-2214 (2006).
Shiroishi M, Kuroki K, Rasubala L, Tsumoto K, Kumagai I, Kurimoto E, Kato K, Kohda D, Maenaka K. Structural basis for recognition of the nonclassical MHC molecule HLA-G by the leukocyte Ig-like receptor B2 (LILRB2/LIR2/ILT4/CD85d). Proc. Natl. Acad. Sci. U.S.A. 103: 16412-16417 (2006). *
Shiroishi M, Maenaka K. Crystallization and preliminary X-ray analysis of the low-affinity complex between human leukocyte antigen-G (HLA-G) and leukocyte Ig-like receptor B2 (LILRB2). Protein Pept. Lett. 16: 447-449 (2009).
Shiryaev SA, Savinov AY, Cieplak P, Ratnikov BI, Motamedchaboki K, Smith JW, Strongin AY. Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis. PLoS ONE 4: e4952 (2009). *
Shofner JD, Vasquez JG, Berger CL, Edelson RL. Improved generation of anti-tumor immunity by antigen dose limitation. J. Immune Based Ther. Vaccines 5: 2 (2007).
Shojima J, Tanaka G, Keicho N, Tamiya G, Ando S, Oka A, Inoue Y, Suzuki K, Sakatani M, Okada M, Kobayashi N, Toyota E, Kudo K, Kajiki A, Nagai H, Kurashima A, Oketani N, Hayakawa H, Takemura T, Nakata K, Ito H, Morita T, Matsushita I, Hijikata M, et al. Identification of MICA as a susceptibility gene for pulmonary Mycobacterium avium complex infection. J. Infect. Dis. 199: 1707-1715 (2009). *
Short AD, Catchpole B, Kennedy LJ, Barnes A, Lee AC, Jones CA, Fretwell N, Ollier WE. T cell cytokine gene polymorphisms in canine diabetes mellitus. Vet. Immunol. Immunopathol. 128: 137-146 (2009). *
Shoukry NH, Lavoie PM, Thibodeau J, D'Souza S, Sekaly RP. MHC class II-dependent peptide antigen versus superantigen presentation to T cells. Hum. Immunol. 54: 194-201 (1997).
Shrestha S, Wang C, Aissani B, Wilson CM, Tang J, Kaslow RA. Interleukin-10 gene (IL10) polymorphisms and human papillomavirus clearance among immunosuppressed adolescents. Cancer Epidemiol. Biomarkers Prev. 16: 1626-1632 (2007). *
Shtauvere-Brameus A, Ghaderi M, Rumba I, Sanjeevi CB. Microsatellite allele 5 of MHC class I chain-related gene A increases the risk for insulin-dependent diabetes mellitus in Latvians. Ann. N. Y. Acad. Sci. 958: 349-352 (2002). *
Si S, Sun Y, Li Z, Ge W, Zhang X, Hu P, Huang Y, Chen G, Song H, Huang Y, Ma B, Li X, Sui Y. Gene therapy by membrane-expressed superantigen for alpha-fetoprotein-producing hepatocellular carcinoma. Gene Ther. 13: 1603-1610 (2006). *
Sia C, Weinem M. Genetic susceptibility to type 1 diabetes in the intracellular pathway of antigen processing - a subject review and cross-study comparison. Rev. Diabet. Stud. 2: 40-52 (2005). *
Sia C, Weinem M. The role of HLA class I gene variation in autoimmune diabetes. Rev. Diabet. Stud. 2: 97-109 (2005). *
Siala M, Mahfoudh N, Fourati H, Gdoura R, Younes M, Kammoun A, Chour I, Meddeb N, Gaddour L, Hakim F, Baklouti S, Bargaoui N, Sellami S, Hammami A, Makni H. MHC class I and class II genes in Tunisian patients with reactive and undifferentiated arthritis. Clin. Exp. Rheumatol. 27: 208-213 (2009).
Sibbitt WL Jr. Oncogenes, growth factors, and autoimmune diseases (review). Anticancer Res. 11: 97-113 (1991).
Sidney J, Peters B, Frahm N, Brander C, Sette A. HLA class I supertypes: a revised and updated classification. BMC Immunol. 9: 1 (2008). *
Siegel AM, Herskowitz JH, Speck SH. The MHV68 M2 protein drives IL-10 dependent B cell proliferation and differentiation. PLoS Pathog. 4: e1000039 (2008). *
Siegel M, Xia J, Khosla C. Structure-based design of alpha-amido aldehyde containing gluten peptide analogues as modulators of HLA-DQ2 and transglutaminase 2. Bioorg. Med. Chem. 15: 6253-6261 (2007). *
Siegel RM, Katsumata M, Komori S, Wadsworth S, Gill-Morse L, Jerrold-Jones S, Bhandoola A, Greene MI, Yui K. Mechanisms of autoimmunity in the context of T-cell tolerance: insights from natural and transgenic animal model systems. Immunol. Rev. 118: 165-192 (1990).
Siegemund S, Alber G. Cryptococcus neoformans activates bone marrow-derived conventional dendritic cells rather than plasmacytoid dendritic cells and down-regulates macrophages. FEMS Immunol. Med. Microbiol. 52: 417-427 (2008). *
Sieker F, Straatsma TP, Springer S, Zacharias M. Differential tapasin dependence of MHC class I molecules correlates with conformational changes upon peptide dissociation: a molecular dynamics simulation study. Mol. Immunol. 45: 3714-3722 (2008). *
Siemionow M, Izycki D, Ozer K, Ozmen S, Klimczak A. Role of thymus in operational tolerance induction in limb allograft transplant model. Transplantation 81: 1568-1576 (2006).
Sigal LH. Basic science for the clinician 26: tolerance-mechanisms and manifestations. J. Clin. Rheumatol. 11: 113-117 (2005).
Sigal LH. Basic science for the clinician 30: the immunologic synapse. J. Clin. Rheumatol. 11: 234-239 (2005).
Sigal LH. Molecular biology and immunology for clinicians 17: T-cell signal transduction. J. Clin. Rheumatol. 8: 113-116 (2002).
Siglienti I, Chan A, Kleinschnitz C, Jander S, Toyka KV, Gold R, Stoll G. Downregulation of transforming growth factor-beta2 facilitates inflammation in the central nervous system by reciprocal astrocyte/microglia interactions. J. Neuropathol. Exp. Neurol. 66: 47-56 (2007).
Sille FC, Boxem M, Sprengers D, Veerapen N, Besra G, Boes M. Distinct requirements for CD1d intracellular transport for development of Valpha14 iNKT cells. J. Immunol. 183: 1780-1788 (2009).
Sille FC, Visser A, Boes M. T cell priming by tissue-derived dendritic cells: new insights from recent murine studies. Cell. Immunol. 237: 77-85 (2005). *
Silman AJ, Pearson JE. Epidemiology and genetics of rheumatoid arthritis. Arthritis Res. 4 Suppl. 3: S265-S272 (2002). *
Silva ME, Mory D, Davini E. Genetic and humoral autoimmunity markers of type 1 diabetes: from theory to practice. Arq. Bras. Endocrinol. Metabol. 52: 166-180 (2008). *
Silver J, Ferrone S. Structural polymorphism of human DR antigens. Nature 279: 436-437 (1979).
Silver J, Russell WA. Structural polymorphism of I-E subregion antigens determined by a gene in the H-2K to I-B genetic interval. Nature 279: 437-439 (1979).
Silverberg MS, Mirea L, Bull SB, Murphy JE, Steinhart AH, Greenberg GR, McLeod RS, Cohen Z, Wade JA, Siminovitch KA. A population- and family-based study of Canadian families reveals association of HLA DRB1*0103 with colonic involvement in inflammatory bowel disease. Inflamm. Bowel Dis. 9: 1-9 (2003). *
Silvestre R, Silva AM, Cordeiro-da-Silva A, Ouaissi A. The contribution of Toll-like receptor 2 to the innate recognition of a Leishmania infantum silent information regulator 2 protein. Immunology 128: 484-499 (2009). *
Simmonds MJ, Howson JM, Heward JM, Carr-Smith J, Franklyn JA, Todd JA, Gough SC. A novel and major association of HLA-C in Graves' disease that eclipses the classical HLA-DRB1 effect. Hum. Mol. Genet. 16: 2149-2153 (2007). *
Simmonds S, Mason D. Induction of autoimmune disease by depletion of regulatory T cells. Curr. Protoc. Immunol. Chapter 15: Unit 15.12 (2001).
Simon CO, Holtappels R, Tervo HM, Bohm V, Daubner T, Oehrlein-Karpi SA, Kuhnapfel B, Renzaho A, Strand D, Podlech J, Reddehase MJ, Grzimek NK. CD8 T cells control cytomegalovirus latency by epitope-specific sensing of transcriptional reactivation. J. Virol. 80: 10436-10456 (2006). *
Simone LC, Wang X, Solheim JC. A transmembrane tail: interaction of tapasin with TAP and the MHC class I molecule. Mol. Immunol. 46: 2147-2150 (2009). *
Simone LC, Wang X, Tuli A, Solheim JC. Effect of a tapasin mutant on the assembly of the mouse MHC class I molecule H2-K(d). Immunol. Cell Biol. Aug 18 [Epub ahead of print] (2009). *
S�mova J, Indrova M, Bieblova J, Mikyskova R, Bubenik J, Reinis M. Therapy of minimal residual tumour disease: beta-galactosylceramide inhibits growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy. Int. J. Cancer Sep 8 [Epub ahead of print] (2009). *
Simpson E. A historical perspective on immunological privilege. Immunol. Rev. 213: 12-22 (2006). *
Sims AM, Barnardo M, Herzberg I, Bradbury L, Calin A, Wordsworth BP, Darke C, Brown MA. Non-B27 MHC associations of ankylosing spondylitis. Genes Immun. 8: 115-123 (2007). *
Sindhi R, Higgs BW, Weeks DE, Ashokkumar C, Jaffe R, Kim C, Wilson P, Chien N, Glessner J, Talukdar A, Mazariegos G, Barmada MM, Frackleton E, Petro N, Eckert A, Hakonarson H, Ferrell R. Genetic variants in major histocompatibility complex-linked genes associate with pediatric liver transplant rejection. Gastroenterology 135: 830-839.e10 (2008). *
Singal DP, Li J, Lei K. Genetics of rheumatoid arthritis (RA): two separate regions in the major histocompatibility complex contribute to susceptibility to RA. Immunol. Lett. 69: 301-306 (1999).
Singal DP, Li J, Ye M, Lei K. D6S273 microsatellite polymorphism and susceptibility to rheumatoid arthritis. Tissue Antigens 52: 353-358 (1998).
Singal DP, Li J, Zhu Y. Genetic basis for rheumatoid arthritis. Arch. Immunol. Ther. Exp. (Warsz.) 47: 307-311 (1999).
Singal DP, Ye M, Qiu X, D'Souza M. Polymorphisms in the TAP2 gene and their association with rheumatoid arthritis. Clin. Exp. Rheumatol. 12: 29-33 (1994).
Singh AK, Wilson MT, Hong S, Olivares-Villagomez D, Du C, Stanic AK, Joyce S, Sriram S, Koezuka Y, Van Kaer L. Natural killer T cell activation protects mice against experimental autoimmune encephalomyelitis. J. Exp. Med. 194: 1801-1811 (2001). *
Singh I, McConnell I, Blacklaws B. Immune response to individual maedi-visna virus gag antigens. J. Virol. 80: 912-919 (2006). *
Singh P, Kaur G, Sharma G, Mehra NK. Immunogenetic basis of HIV-1 infection, transmission and disease progression. Vaccine 26: 2966-2980 (2008). *
Singh P, Kohr D, Kaps M, Blaes F. Influence of statins on MHC class I expression. Ann. N. Y. Acad. Sci. 1173: 746-751 (2009). *
Singh RP, La Cava A, Hahn BH. pConsensus peptide induces tolerogenic CD8+ T cells in lupus-prone (NZB x NZW)F1 mice by differentially regulating Foxp3 and PD1 molecules. J. Immunol. 180: 2069-2080 (2008). *
Singh RP, La Cava A, Wong M, Ebling F, Hahn BH. CD8+ T cell-mediated suppression of autoimmunity in a murine lupus model of peptide-induced immune tolerance depends on Foxp3 expression. J. Immunol. 178: 7649-7657 (2007). *
Singh UP, Singh S, Singh R, Cong Y, Taub DD, Lillard JW. CXCL10-producing mucosal CD4(+) T cells, NK cells, and NKT cells are associated with chronic colitis in IL-10(-/-) mice, which can be abrogated by anti-CXCL10 antibody inhibition. J. Interferon Cytokine Res. 28: 31-43 (2008). *
Single RM, Meyer D, Mack SJ, Lancaster A, Erlich HA, Thomson G. 14th International HLA and Immunogenetics Workshop: report of progress in methodology, data collection, and analyses. Tissue Antigens 69 Suppl. 1: 185-187 (2007). *
Sinha P, Snyder JA, Kim EY, Moudgil KD. The major histocompatibility complex haplotypes dictate and the background genes fine-tune the dominant versus the cryptic response profile of a T-cell determinant within a native antigen: relevance to disease susceptibility and vaccination. Scand. J. Immunol. 65: 158-265 (2007). *
Sinha S, Kaler LJ, Proctor TM, Teuscher C, Vandenbark AA, Offner H. IL-13-mediated gender difference in susceptibility to autoimmune encephalomyelitis. J. Immunol. 180: 2679-2685 (2008). *
Sioud M. Does our current understanding of immune tolerance, autoimmunity, and immunosuppressive mechanisms facilitate the design of efficient cancer vaccines? Scand. J. Immunol. 70: 516-525 (2009). *
Siracusa MC, Overstreet MG, Housseau F, Scott AL, Klein SL. 17beta-Estradiol alters the activity of conventional and IFN-producing killer dendritic cells. J. Immunol. 180: 1423-1431 (2008). *
Sirianni MC, Campagna M, Scaramuzzi D, Carbonari M, Toschi E, Bacigalupo I, Monini P, Ensoli B. Control of human herpes virus type 8-associated diseases by NK cells. Ann. N. Y. Acad. Sci. 1096: 37-43 (2007). *
Sjoholm AG, Kjellman NI, Low B. C4 allotypes and HLA-DR antigens in the family of a patient with C4 deficiency. Clin. Genet. 28: 385-393 (1985).
Skanes V, Larsen B, Sampson-Murphy L, Farid NR. Polymorphism of the fourth component of complement in Graves' disease and type I diabetes mellitus. Clin. Invest. Med. 8: 126-132 (1985).
Skanes VM, Barnard J, Farid N, Marshall WH, Murphy L, Rideout D, Taylor R, Xidos G, Larsen B. Class III alleles and high-risk MHC haplotypes in type I diabetes mellitus, Graves' disease and Hashimoto's thyroiditis. Mol. Biol. Med. 3: 143-157 (1986).
Skarlas T, Panou-Pomonis E, Kluczyk A, Szewczuk Z, Zimecki M, Kosmopoulou A, Sakarellos-Daitsiotis M, Sakarellos C. HLA-DQ7 beta(1) and beta(2) derived peptides as immunomodulators. J. Pept. Sci. 15: 296-304 (2009). *
Skokos D, Shakhar G, Varma R, Waite JC, Cameron TO, Lindquist RL, Schwickert T, Nussenzweig MC, Dustin ML. Peptide-MHC potency governs dynamic interactions between T cells and dendritic cells in lymph nodes. Nat. Immunol. 8: 835-844 (2007). *
Skov L, Baadsgaard O. Superantigens. Do they have a role in skin diseases? Arch. Dermatol. 131: 829-832 (1995).
Skretkowicz J, Skretkowicz-Szarmach K. Genetics in rheumatoid arthritis (RA). Pol. Merkuriusz. Lek. 20: 468-470 (2006).
Skretkowicz J, Skretkowicz-Szarmach K. Genetics in systemic sclerosis. Pol. Merkuriusz. Lek. 20: 117-120 (2006).
Slager SL, Carleu L, Chung WK, Jackson T, Winchester RJ, Hodge SE, Gulko PS. The IDDM13 region containing the insulin-like growth factor binding protein-5 (IGFBP5) gene on chromosome 2q33-q36 and the genetic susceptibility to rheumatoid arthritis. Genes Immun. 3: 110-113 (2002). *
Slingluff CL Jr, Chianese-Bullock KA, Bullock TN, Grosh WW, Mullins DW, Nichols L, Olson W, Petroni G, Smolkin M, Engelhard VH. Immunity to melanoma antigens: from self-tolerance to immunotherapy. Adv. Immunol. 90C: 243-295 (2006).
Sloan VS, Cameron P, Porter G, Gammon M, Amaya M, Mellins E, Zaller DM. Mediation by HLA-DM of dissociation of peptides from HLA-DR. Nature 375: 802-806 (1995). *
Slomov E, Loewenthal R, Korostishevsky M, Goldberg I, Brenner S, Gazit E. Pemphigus vulgaris is associated with the transporter associated with antigen processing (TAP) system. Hum. Immunol. 66: 1213-1222 (2005).
Smerdel-Ramoya A, Finholt C, Lilleby V, Gilboe IM, Harbo HF, Maslinski S, Forre O, Thorsby E, Lie BA. Systemic lupus erythematosus and the extended major histocompatibility complex - evidence for several predisposing loci. Rheumatology (Oxford) 44: 1368-1373 (2005). *
Smith DM, Lunney JK, Martens GW, Ando A, Lee JH, Ho CS, Schook L, Renard C, Chardon P. Nomenclature for factors of the SLA class-I system, 2004. Tissue Antigens 65: 136-149 (2005). *
Smith JA, Marker-Hermann E, Colbert RA. Pathogenesis of ankylosing spondylitis: current concepts. Best Pract. Res. Clin. Rheumatol. 20: 571-591 (2006).
Smith KD, Kurago ZB, Lutz CT. Conformational changes in MHC class I molecules. Antibody, T-cell receptor, and NK cell recognition in an HLA-B7 model system. Immunol. Res. 16: 243-259 (1997).
Smith M, Bittner JG 4th, White S, Smith D, Horuzsko A. HLA-G-treated tolerogenic dendritic cells induce tolerogenic potential by increasing expression of B7-1 (CD80) molecules. Transplant. Proc. 40: 1598-603 (2008).
Smith MA, Moylan JS, Smith JD, Li W, Reid MB. IFN-gamma does not mimic the catabolic effects of TNF-alpha. Am. J. Physiol. Cell Physiol. 293: C1947-C1952 (2007). *
Smith RL, Warren RB, Griffiths CE, Worthington J. Genetic susceptibility to psoriasis: an emerging picture. Genome Med. 1: 72 (2009). *
Smith TR, Kumar V. Revival of CD8(+) Treg-mediated suppression. Trends Immunol. 29: 337-342 (2008). *
Smith TR, Tang X, Maricic I, Garcia Z, Fanchiang S, Kumar V. Dendritic cells use endocytic pathway for cross-priming class Ib MHC-restricted CD8alphaalpha+TCRalphabeta+ T cells with regulatory properties. J. Immunol. 182: 6959-6968 (2009).
Smith WP, Vu Q, Li SS, Hansen JA, Zhao LP, Geraghty DE. Toward understanding MHC disease associations: partial resequencing of 46 distinct HLA haplotypes. Genomics 87: 561-571 (2006). *
Smith-Berdan S, Gille D, Weissman IL, Christensen JL. Reversal of autoimmune disease in lupus-prone NZB/NZW mice by nonmyeloablative transplantation of purified allogeneic hematopoietic stem cells. Blood 110: 1370-1378 (2007). *
Smits EL, Ponsaerts P, Van de Velde AL, Van Driessche A, Cools N, Lenjou M, Nijs G, Van Bockstaele DR, Berneman ZN, Van Tendeloo VF. Proinflammatory response of human leukemic cells to dsRNA transfection linked to activation of dendritic cells. Leukemia 21: 1691-1699 (2007).
Smyth LA, Herrera OB, Golshayan D, Lombardi G, Lechler RI. A novel pathway of antigen presentation by dendritic and endothelial cells: implications for allorecognition and infectious diseases. Transplantation 82 Suppl. 1: S15-S18 (2006).
Smyth LJ, Kirby JA, Cunningham AC. Role of the mucosal integrin alpha(E)(CD103)beta(7) in tissue-restricted cytotoxicity. Clin. Exp. Immunol. 149: 162-170 (2007). *
Snijders A, Elferink DG, Geluk A, van Der Zanden AL, Vos K, Schreuder GM, Breedveld FC, de Vries RR, Zanelli EH. An HLA-DRB1-derived peptide associated with protection against rheumatoid arthritis is naturally processed by human APCs. J. Immunol. 166: 4987-4993 (2001). *
Snyder JA, Demchuk E, McCanlies EC, Schuler CR, Kreiss K, Andrew ME, Frye BL, Ensey JS, Stanton ML, Weston A. Impact of negatively charged patches on the surface of MHC class II antigen-presenting proteins on risk of chronic beryllium disease. J. R. Soc. Interface. 5: 749-758 (2008). *
So AK, Fielder AH, Warner CA, Isenberg DA, Batchelor JR, Walport MJ. DNA polymorphism of major histocompatibility complex class II and class III genes in systemic lupus erythematosus. Tissue Antigens 35: 144-147 (1990).
Soam SS, Khan F, Bhasker B, Mishra BN. Prediction of MHC class I binding peptides using probability distribution functions. Bioinformation 3: 403-408 (2009). *
Sofi MH, Liu Z, Zhu L, Yu Q, Kaplan MH, Chang CH. Regulation of IL-17 expression by the developmental pathway of CD4 T cells in the thymus. Mol. Immunol. Jan 15 [Epub ahead of print] (2010). *
Sola C, Andre P, Lemmers C, Fuseri N, Bonnafous C, Blery M, Wagtmann NR, Romagne F, Vivier E, Ugolini S. Genetic and antibody-mediated reprogramming of natural killer cell missing-self recognition in vivo. Proc. Natl. Acad. Sci. U.S.A. 106: 12879-12884 (2009). *
Soll SJ, Stewart BS, Lehman N. Conservation of MHC class II DOA sequences among carnivores. Tissue Antigens 65: 283-286 (2005). *
Sombekke MH, Lukas C, Crusius JB, Tejedor D, Killestein J, Arteta D, Martinez A, Uitdehaag BM, Knol DL, Pena AS, Geurts JJ, De Jager PL, Barkhof F, Vrenken H, Polman CH. HLA-DRB1*1501 and spinal cord magnetic resonance imaging lesions in multiple sclerosis. Arch. Neurol. 66: 1531-1536 (2009). *
Sommandas V, Rutledge EA, Van Yserloo B, Fuller J, Lernmark A, Drexhage HA. Defects in differentiation of bone-marrow derived dendritic cells of the BB rat are partly associated with IDDM2 (the lyp gene) and partly associated with other genes in the BB rat background. J. Autoimmun. 25: 46-56 (2005).
Sommer SS. The importance of immune gene variability (MHC) in evolutionary ecology and conservation. Front. Zool. 2: 16 (2005).
Song J, Ito T, Matsuda C, Miao G, Tanemura M, Nishida T, Nozawa M, Matsuda H, Sawa Y. Inhibition of donor-derived T cells trafficking into target organs by FTY720 during acute graft-versus-host disease in small bowel transplantation. Clin. Exp. Immunol. 146: 85-92 (2006). *
Song Q, Han Q, Bradshaw EM, Kent SC, Raddassi K, Nilsson B, Nepom GT, Hafler DA, Love JC. On-chip activation and subsequent detection of individual antigen-specific T cells. Anal. Chem. Dec 14 [Epub ahead of print] (2009). *
Song X, Ye D, Liu B, Cui J, Zhao X, Yi L, Liang J, Song J, Zhang Z, Zhao Q. Combination of all-trans retinoic acid and a human papillomavirus therapeutic vaccine suppresses the number and function of immature myeloid cells and enhances antitumor immunity. Cancer Sci. 100: 334-340 (2009). *
Soto-Vega E, Garcia-Munoz R, Richaud-Patin Y, Zuniga-Ramos J, Crispin JC, Diaz-Jouanen E, Flores-Suarez LF, Llorente L, Granados J. Class I and class II MHC polymorphisms in Mexican patients with Behcet's disease. Immunol. Lett. 93: 211-215 (2004).
Souwer Y, Chamuleau ME, van de Loosdrecht AA, Tolosa E, Jorritsma T, Muris JJ, Dinnissen-van Poppel MJ, Snel SN, van de Corput L, Ossenkoppele GJ, Meijer CJ, Neefjes JJ, Marieke van Ham S. Detection of aberrant transcription of major histocompatibility complex class II antigen presentation genes in chronic lymphocytic leukaemia identifies HLA-DOA mRNA as a prognostic factor for survival. Br. J. Haematol. 145: 334-343 (2009).
Soylemezoglu O, Peru H, Gonen S, Cetinyurek A, Buyan N. HLA-DRB1 alleles and Henoch-Schonlein purpura: susceptibility and severity of disease. J. Rheumatol. 35: 1165-1168 (2008). *
Spachidou MP, Bourazopoulou E, Maratheftis CI, Kapsogeorgou EK, Moutsopoulos HM, Tzioufas AG, Manoussakis MN. Expression of functional Toll-like receptors by salivary gland epithelial cells: increased mRNA expression in cells derived from patients with primary Sjogren's syndrome. Clin. Exp. Immunol. 147: 497-503 (2007). *
Speak AO, Cerundolo V, Platt FM. CD1d presentation of glycolipids. Immunol. Cell Biol. 86: 588-597 (2008). *
Spengler U, Pape GR, Hoffmann RM, Johnson JP, Eisenburg J, Paumgartner G, Riethmuller G. Differential expression of MHC class II subregion products on bile duct epithelial cells and hepatocytes in patients with primary biliary cirrhosis. Hepatology 8: 459-462 (1988).
Spies T, Blanck G, Bresnahan M, Sands J, Strominger JL. A new cluster of genes within the human major histocompatibility complex. Science 243: 214-217 (1989). *
Spies T, Bresnahan M, Strominger JL. Human major histocompatibility complex contains a minimum of 19 genes between the complement cluster and HLA-B. Proc. Natl. Acad. Sci. U.S.A. 86: 8955-8958 (1989). *
Sprangers B, Fevery S, Wijmeersch BV, Somer LD, Waer M, Billiau AD. Can graft-versus-leukemia reactivity be dissociated from graft-versus-host disease? Front. Biosci. 12: 4568-4594 (2007).
Sprengers D, Sille FC, Derkow K, Besra GS, Janssen HL, Schott E, Boes M. Critical role for CD1d-restricted invariant NKT cells in stimulating intrahepatic CD8 T-cell responses to liver antigen. Gastroenterology 134: 2132-2143 (2008). *
Spyranti Z, Dalkas GA, Spyroulias GA, Mantzourani ED, Mavromoustakos T, Friligou I, Matsoukas JM, Tselios TV. Putative bioactive conformations of amide linked cyclic myelin basic protein peptide analogues associated with experimental autoimmune encephalomyelitis. J. Med. Chem. 50: 6039-6047 (2007). *
Srinivasan KN, Zhang GL, Khan AM, August JT, Brusic V. Prediction of class I T-cell epitopes: evidence of presence of immunological hot spots inside antigens. Bioinformatics 20 Suppl. 1: i297-i302 (2004). *
Srivastava P. Roles of heat-shock proteins in innate and adaptive immunity. Nat. Rev. Immunol. 2: 185-194 (2002). *
Stadinski BD, Delong T, Reisdorph N, Reisdorph R, Powell RL, Armstrong M, Piganelli JD, Barbour G, Bradley B, Crawford F, Marrack P, Mahata SK, Kappler JW, Haskins K. Chromogranin A is an autoantigen in type 1 diabetes. Nat. Immunol. Feb 7 [Epub ahead of print] (2010). *
Stammers M, Rowen L, Rhodes D, Trowsdale J, Beck S. BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse. Immunogenetics 51: 373-382 (2000). *
Stanislawska J, Interewicz B, Durlik M, Olszewski WL. Human splenic dendritic cells react differently to bacterial and allogeneic antigens. Transplant. Proc. 38: 340-341 (2006). *
Stanworth SJ, Turner DM, Brown J, McCloskey D, Brown C, Provan D, Navarrete CV, Newland AC. Major histocompatibility complex susceptibility genes and immune thrombocytopenic purpura in Caucasian adults. Hematology 7: 119-121 (2002).
Starodubova ES, Boberg A, Litvina M, Morozov A, Petrakova NV, Timofeev A, Latyshev O, Tunitskaya V, Wahren B, Isaguliants MG, Karpov VL. HIV-1 reverse transcriptase artificially targeted for proteasomal degradation induces a mixed Th1/Th2-type immune response. Vaccine 26: 5170-5176 (2008). *
Starr TK, Jameson SC, Hogquist KA. Positive and negative selection of T cells. Annu. Rev. Immunol. 21: 139-176 (2003). *
Stary G, Bangert C, Tauber M, Strohal R, Kopp T, Stingl G. Tumoricidal activity of TLR7/8-activated inflammatory dendritic cells. J. Exp. Med. 204: 1441-1451 (2007). *
Stastny P, Zou Y, Fan Y, Qin Z, Lavingia B. The emerging issue of MICA antibodies: antibodies to MICA and other antigens of endothelial cells. Contrib. Nephrol. 162: 99-106 (2009).
Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietilainen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, et al. Common variants conferring risk of schizophrenia. Nature 460: 744-747 (2009). *
Steffens S, Mach F. Anti-inflammatory properties of statins. Semin. Vasc. Med. 4: 417-422 (2004).
Steinle A, Li P, Morris DL, Groh V, Lanier LL, Strong RK, Spies T. Interactions of human NKG2D with its ligands MICA, MICB, and homologs of the mouse RAE-1 protein family. Immunogenetics 53: 279-287 (2001).
Steinman L. Elaborate interactions between the immune and nervous systems. Nat. Immunol. 5: 575-581 (2004). *
Steinman RM. Dendritic cells and the control of immunity: enhancing the efficiency of antigen presentation. Mt. Sinai J. Med. 68: 106-166 (2001). *
Stelekati E, Bahri R, D'Orlando O, Orinska Z, Mittrucker HW, Langenhaun R, Glatzel M, Bollinger A, Paus R, Bulfone-Paus S. Mast cell-mediated antigen presentation regulates CD8(+) T cell effector functions. Immunity 31: 665-676 (2009). *
Stelekati E, Orinska Z, Bulfone-Paus S. Mast cells in allergy: innate instructors of adaptive responses. Immunobiology 212: 505-519 (2007).
Stenszky V, Kozma L, Balazs C, Bear JC, Farid NR. The role of HLA antigens in the manifestation and course of Graves' disease. Mol. Biol. Med. 3: 53-62 (1986).
Stephan CH, Sauve S, Fournier M, Brousseau P. Use of proliferation tests to evaluate the effects of complexing agents on beryllium toxicity. J. Appl. Toxicol. 29: 27-35 (2008). *
Stephens GL, Andersson J, Shevach EM. Distinct subsets of FoxP3+ regulatory T cells participate in the control of immune responses. J. Immunol. 178: 6901-6911 (2007). *
Stephens HA. MHC haplotypes, MICA genes and the 'wonderland' of NK receptor polymorphism. Trends Immunol. 23: 385-386 (2002). *
Stephens HA. MICA and MICB genes: can the enigma of their polymorphism be resolved? Trends Immunol. 22: 378-385 (2001). *
Steptoe RJ, Ritchie JM, Jones LK, Harrison LC. Autoimmune diabetes is suppressed by transfer of proinsulin-encoding gr-1+ myeloid progenitor cells that differentiate in vivo into resting dendritic cells. Diabetes 54: 434-442 (2005). *
Stern JN, Keskin DB. Strategies for the identification of loci responsible for the pathogenesis of multiple sclerosis. Cell. Mol. Biol. Lett. 13: 656-666 (2008). *
Stern JN, Keskin DB, Barteneva N, Zuniga J, Yunis EJ, Ahmed AR. Possible role of natural killer cells in pemphigus vulgaris - preliminary observations. Clin. Exp. Immunol. 152: 472-481 (2008). *
Stern LJ, Calvo-Calle JM. HLA-DR: molecular insights and vaccine design. Curr. Pharm. Des. 15: 3249-3261 (2009).
Stern M, Ruggeri L, Capanni M, Mancusi A, Velardi A. Human leukocyte antigens A23, A24 and A32 but not A25 are ligands for KIR3DL1. Blood 112: 708-710 (2008). *
Stewart C, Cha S, Caudle RM, Berg K, Katz J. Decreased levels of soluble receptor for advanced glycation end products in patients with primary Sjogren's syndrome. Rheumatol. Int. 28: 771-776 (2008). *
Stewart CA, Horton R, Allcock RJ, Ashurst JL, Atrazhev AM, Coggill P, Dunham I, Forbes S, Halls K, Howson JM, Humphray SJ, Hunt S, Mungall AJ, Osoegawa K, Palmer S, Roberts AN, Rogers J, Sims S, Wang Y, Wilming LG, Elliott JF, De Jong PJ, Sawcer S, et al. Complete MHC haplotype sequencing for common disease gene mapping. Genome Res. 14: 1176-1187 (2004). *
Stewart CA, Laugier-Anfossi F, Vely F, Saulquin X, Riedmuller J, Tisserant A, Gauthier L, Romagne F, Ferracci G, Arosa FA, Moretta A, Sun PD, Ugolini S, Vivier E. Recognition of peptide-MHC class I complexes by activating killer immunoglobulin-like receptors. Proc. Natl. Acad. Sci. U.S.A. 102: 13224-13229 (2005). *
Stewart-Jones G, Wadle A, Hombach A, Shenderov E, Held G, Fischer E, Kleber S, Stenner-Liewen F, Bauer S, McMichael A, Knuth A, Abken H, Hombach AA, Cerundolo V, Jones EY, Renner C. Rational development of high-affinity T-cell receptor-like antibodies. Proc. Natl. Acad. Sci. U.S.A. 106: 5784-5788 (2009). *
Stober CB, Brode S, White JK, Popoff JF, Blackwell JM. Slc11a1 (formerly Nramp1) is expressed in dendritic cells and influences MHC class II expression and antigen presenting cell function. Infect. Immun. 75: 5059-5067 (2007). *
Stoffels RJ, Spencer HG. An asymmetric model of heterozygote advantage at major histocompatibility complex genes: degenerate pathogen recognition and intersection advantage. Genetics 178: 1473-1489 (2008). *
Stohl W, Xu D, Kim KS, David CS, Allison JP. MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4). Int. Immunol. 16: 895-904 (2004). *
Stohl W, Xu D, Metzger TE, Kim KS, Morel L, Kotzin BL. Dichotomous effects of complete versus partial class II major histocompatibility complex deficiency on circulating autoantibody levels in autoimmune-prone mice. Arthritis Rheum. 50: 2227-2239 (2004). *
Stojakovic M, Salazar-Fontana LI, Tatari-Calderone Z, Badovinac VP, Santori FR, Kovalovsky D, Sant'Angelo D, Harty JT, Vukmanovic S. Adaptable TCR avidity thresholds for negative selection. J. Immunol. 181: 6770-6778 (2008). *
Stone J, Wade JA, Cauch-Dudek K, Ng C, Lindor KD, Heathcote EJ. Human leukocyte antigen class II associations in serum antimitochondrial antibodies (AMA)-positive and AMA-negative primary biliary cirrhosis. J. Hepatol. 36: 8-13 (2002). *
Stone JD, Chervin AS, Kranz DM. T-cell receptor binding affinities and kinetics: impact on T-cell activity and specificity. Immunology 126: 165-176 (2009). *
Strick-Marchand H, Morosan S, Charneau P, Kremsdorf D, Weiss MC. Bipotential mouse embryonic liver stem cell lines contribute to liver regeneration and differentiate as bile ducts and hepatocytes. Proc. Natl. Acad. Sci. U.S.A. 101: 8360-8365 (2004). *
Strobel P, Chuang WY, Chuvpilo S, Zettl A, Katzenberger T, Kalbacher H, Rieckmann P, Nix W, Schalke B, Gold R, Muller-Hermelink HK, Peterson P, Marx A. Common cellular and diverse genetic basis of thymoma-associated myasthenia gravis: role of MHC class II and AIRE genes and genetic polymorphisms. Ann. N. Y. Acad. Sci. 1132: 143-156 (2008). *
Strom TB, Koulmanda M. Recently discovered T cell subsets cannot keep their commitments. J. Am. Soc. Nephrol. 20: 1677-1680 (2009).
Stromnes IM, Cerretti LM, Liggitt D, Harris RA, Goverman JM. Differential regulation of central nervous system autoimmunity by T(H)1 and T(H)17 cells. Nat. Med. 14: 337-342 (2008). *
Stronen E, Abrahamsen IW, Gaudernack G, Walchli S, Munthe E, Buus S, Johansen FE, Lund-Johansen F, Olweus J. Dendritic cells engineered to express defined allo-HLA peptide complexes induce antigen-specific cytotoxic T cells efficiently killing tumour cells. Scand. J. Immunol. 69: 319-328 (2009). *
Strong RK, McFarland BJ. NKG2D and related immunoreceptors. Adv. Protein Chem. 68: 281-312 (2004).
Strug I, Calvo-Calle JM, Green KM, Cruz J, Ennis FA, Evans JE, Stern LJ. Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4(+) T cells from a vaccinated donor. J. Proteome Res. 7: 2703-2711 (2008). *
Stulberg MJ, Wright PW, Dang H, Hanson RJ, Miller JS, Anderson SK. Identification of distal KIR promoters and transcripts. Genes Immun. 8: 124-130 (2007). *
Stuve O, Youssef S, Slavin AJ, King CL, Patarroyo JC, Hirschberg DL, Brickey WJ, Soos JM, Piskurich JF, Chapman HA, Zamvil SS. The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease. J. Immunol. 169: 6720-6732 (2002). *
Su L, Shen L, Clayburgh DR, Nalle SC, Sullivan EA, Meddings JB, Abraham C, Turner JR. Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 136: 551-563 (2009). *
Su Y, Carey G, Maric M, Scott DW. B cells induce tolerance by presenting endogenous peptide-IgG on MHC class II molecules via an IFN-gamma-inducible lysosomal thiol reductase-dependent pathway. J. Immunol. 181: 1153-1160 (2008). *
Suarez BK, Culverhouse R, Jin CH, Hinrichs AL. A search for non-chromosome 6 susceptibility loci contributing to rheumatoid arthritis. BMC Proc. 3 Suppl. 7: S15 (2009). *
Suarez-Almazor ME, Russell AS, LeClercq S. Ankylosing spondylitis in families with two distinct B27 haplotypes: a selective association. Arthritis Rheum. 29: 1510-1514 (1986).
Suarez-Alvarez B, Alonso-Arias R, Bravo-Mendoza C, Lopez-Vazquez A, Ortega T, Baltar JM, Coto E, Ortega F, Lopez-Larrea C. Identification of epitopes and immunodominant regions on the MICA protein defined by alloantibodies from kidney transplant patients. Transplantation 88: S68-S77 (2009).
Suarez-Alvarez B, Lopez-Vazquez A, Diaz-Molina B, Bernardo-Rodriguez MJ, Alvarez-Lopez R, Pascual D, Astudillo A, Martinez-Borra J, Lambert JL, Gonzalez S, Lopez-Larrea C. The predictive value of soluble major histocompatibility complex class I chain-related molecule A (MICA) levels on heart allograft rejection. Transplantation 82: 354-361 (2006).
Sugimura K, Ota M, Matsuzawa J, Katsuyama Y, Ishizuka K, Mochizuki T, Mizuki N, Seki SS, Honma T, Inoko H, Asakura H. A close relationship of triplet repeat polymorphism in MHC class I chain-related gene A (MICA) to the disease susceptibility and behavior in ulcerative colitis. Tissue Antigens 57: 9-14 (2001). *
Sugita K, Kabashima K, Atarashi K, Shimauchi T, Kobayashi M, Tokura Y. Innate immunity mediated by epidermal keratinocytes promotes acquired immunity involving Langerhans cells and T cells in the skin. Clin. Exp. Immunol. 147: 176-183 (2007). *
Suh CH, Freed JH, Cohen PL. T cell reactivity to MHC class II-bound self peptides in systemic lupus erythematosus-prone MRL/lpr mice. J. Immunol. 170: 2229-2235 (2003). *
Suidan GL, Mcdole JR, Chen Y, Pirko I, Johnson AJ. Induction of blood brain barrier tight junction protein alterations by CD8 T cells. PLoS ONE 3: e3037 (2008). *
Sukhikh GT, Nurutdinova RA, Murashko LE, Faizullin LZ. Effect of HLA-compatibility in married couples on the development and severity of gestosis. Bull. Exp. Biol. Med. 143: 222-224 (2007).
Sullivan BA, Nagarajan NA, Kronenberg M. CD1 and MHC II find different means to the same end. Trends Immunol. 26: 282-288 (2005). *
Sullivan LC, Clements CS, Rossjohn J, Brooks AG. The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity. Tissue Antigens 72: 415-424 (2008). *
Sullivan LC, Clements CS, Rossjohn J, Brooks AG. The major histocompatibility complex class Ib molecule HLA-E at the interface between innate and adaptive immunity. Tissue Antigens 72: 415-424 (2008). *
Sullivan LC, Hoare HL, McCluskey J, Rossjohn J, Brooks AG. A structural perspective on MHC class Ib molecules in adaptive immunity. Trends Immunol. 27: 413-420 (2006). *
Sumitran-Holgersson S. Relevance of MICA and other non-HLA antibodies in clinical transplantation. Curr. Opin. Immunol. 20: 607-613 (2008).
Sumnik Z, Cinek O, Bratanic N, Kordonouri O, Kulich M, Roszai B, Arato A, Lebl J, Soltesz G, Danne T, Battelino T, Schober E. Risk of celiac disease in children with type 1 diabetes is modified by positivity for HLA-DQB1*02-DQA1*05 andTNF -308A. Diabetes Care 29: 858-863 (2006). *
Sun CR, Wang CC, Tsang KS, Li J, Zhang H, An YH. Modulation and impact of class I major histocompatibility complex by neural stem cell-derived neurotrophins on neuroregeneration. Med. Hypotheses 68: 176-179 (2007).
Sun D, Krishnan A, Su J, Lawrence R, Zaman K, Fernandes G. Regulation of immune function by calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice. Cell. Immunol. 228: 54-65 (2004). *
Sun K, Li M, Konopleva M, Konoplev S, Stephens LC, Kornblau SM, Frolova O, Wilkins DE, Ma W, Welniak LA, Andreeff M, Murphy WJ. The synthetic triterpenoid, CDDO, suppresses alloreactive T cell responses and teduces murine early acute graft-versus-host disease mortality. Biol. Blood Marrow Transplant. 13: 521-529 (2007).
Sun PD. Structure and function of natural-killer-cell receptors. Immunol. Res. 27: 539-548 (2003). *
Sun Z, Unutmaz D, Zou YR, Sunshine MJ, Pierani A, Brenner-Morton S, Mebius RE, Littman DR. Requirement for RORgamma in thymocyte survival and lymphoid organ development. Science 288: 2369-2373 (2000). *
Sundberg EJ. Molecular recognition of diverse ligands by T-cell receptors. Methods Mol. Biol. 524: 347-359 (2009). *
Sundberg EJ, Deng L, Mariuzza RA. TCR recognition of peptide/MHC class II complexes and superantigens. Semin. Immunol. 19: 262-271 (2007). *
Sundberg JP, Silva KA, Li R, Cox GA, King LE. Adult-onset alopecia areata is a complex polygenic trait in the C3H/HeJ mouse model. J. Invest. Dermatol. 123: 294-297 (2004). *
Suri A, Levisetti MG, Unanue ER. Do the peptide-binding properties of diabetogenic class II molecules explain autoreactivity? Curr. Opin. Immunol. 20: 105-110 (2008). *
Suri A, Walters JJ, Rohrs HW, Gross ML, Unanue ER. First signature of islet beta-cell-derived naturally processed peptides selected by diabetogenic class II MHC molecules. J. Immunol. 180: 3849-3856 (2008). *
Sutkowski N, Conrad B, Thorley-Lawson DA, Huber BT. Epstein-Barr virus transactivates the human endogenous retrovirus HERV-K18 that encodes a superantigen. Immunity 15: 579-589 (2001). *
Suzuki K, Mori A, Ishii KJ, Saito J, Singer DS, Klinman DM, Krause PR, Kohn LD. Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides. Proc. Natl. Acad. Sci. U.S.A. 96: 2285-2290 (1999). *
Suzuki K, Narita T, Yui R, Asakura H, Fujiwara M. Mechanism of the induction of autoimmune disease by graft-versus-host reaction. Role of CD8+ cells in the development of hepatic and ductal lesions induced by CD4+ cells in MHC class I plus II-different host. Lab. Invest. 70: 609-619 (1994).
Suzuki R, Utoguchi N, Kawamura K, Kadowaki N, Okada N, Takizawa T, Uchiyama T, Maruyama K. Development of effective antigen delivery carrier to dendritic cells via Fc receptor in cancer immunotherapy. Yakugaku Zasshi 127: 301-306 (2007).
Svajger U, Obermajer N, Jeras M. Dendritic cells treated with resveratrol during differentiation from monocytes gain substantial tolerogenic properties upon activation. Immunology Dec 14 [Epub ahead of print] (2009). *
Svensson M, Marsal J, Uronen-Hansson H, Cheng M, Jenkinson W, Cilio C, Jacobsen SE, Sitnicka E, Anderson G, Agace WW. Involvement of CCR9 at multiple stages of adult T lymphopoiesis. J. Leukoc. Biol. 83: 156-164 (2008). *
Swanberg M, Lidman O, Padyukov L, Eriksson P, Akesson E, Jagodic M, Lobell A, Khademi M, Borjesson O, Lindgren CM, Lundman P, Brookes AJ, Kere J, Luthman H, Alfredsson L, Hillert J, Klareskog L, Hamsten A, Piehl F, Olsson T. MHC2TA is associated with differential MHC molecule expression and susceptibility to rheumatoid arthritis, multiple sclerosis and myocardial infarction. Nat. Genet. 37: 486-494 (2005). *
Swanson PA 2nd, Pack CD, Hadley A, Wang CR, Stroynowski I, Jensen PE, Lukacher AE. An MHC class Ib-restricted CD8 T cell response confers antiviral immunity. J. Exp. Med. 205: 1647-1657 (2008). *
Szanto S, Bardos T, Szabo Z, David CS, Buzas EI, Mikecz K, Glant TT. Induction of arthritis in HLA-DR4-humanized and HLA-DQ8-humanized mice by human cartilage proteoglycan aggrecan but only in the presence of an appropriate (non-MHC) genetic background. Arthritis Rheum. 50: 1984-1995 (2004). *
Szostecki C, Guldner HH, Netter HJ, Will H. Isolation and characterization of cDNA encoding a human nuclear antigen predominantly recognized by autoantibodies from patients with primary biliary cirrhosis. J. Immunol. 145: 4338-4347 (1990).
Szostecki C, Will H, Netter HJ, Guldner HH. Autoantibodies to the nuclear Sp100 protein in primary biliary cirrhosis and associated diseases: epitope specificity and immunoglobulin class distribution. Scand. J. Immunol. 36: 555-564 (1992).
Szyld P, Jagiello P, Csernok E, Gross WL, Epplen JT. On the Wegener granulomatosis associated region on chromosome 6p21.3. BMC Med. Genet. 7: 21 (2006). *
Tabeta K, Hoebe K, Janssen EM, Du X, Georgel P, Crozat K, Mudd S, Mann N, Sovath S, Goode J, Shamel L, Herskovits AA, Portnoy DA, Cooke M, Tarantino LM, Wiltshire T, Steinberg BE, Grinstein S, Beutler B. The Unc93b1 mutation 3d disrupts exogenous antigen presentation and signaling via Toll-like receptors 3, 7 and 9. Nat. Immunol. 7: 156-164 (2006). *
Tahan F, Patiroglu T. Plasma soluble human leukocyte antigen G levels in asthmatic children. Int. Arch. Allergy Immunol. 141: 213-216 (2006).
Tahvanainen J, Pykalainen M, Kallonen T, Lahteenmaki H, Rasool O, Lahesmaa R. Enrichment of nucleofected primary human CD4(+) T cells: a novel and efficient method for studying gene function and role in human primary T helper cell differentiation. J. Immunol. Methods 310: 30-39 (2006). *
Tailor P, Tamura T, Ozato K. IRF family proteins and type I interferon induction in dendritic cells. Cell Res. 16: 134-140 (2006).
Tait B, Mackay IR, Board P, Coggan M, Emery P, Eckardt G. HLA A1, B8, DR3 extended haplotypes in autoimmune chronic hepatitis. Gastroenterology 97: 479-481 (1989).
Tait KF, Gough SC. The genetics of autoimmune endocrine disease. Clin. Endocrinol. (Oxf.) 59: 1-11 (2003). *
Tajima M, Wakita D, Noguchi D, Chamoto K, Yue Z, Fugo K, Ishigame H, Iwakura Y, Kitamura H, Nishimura T. IL-6-dependent spontaneous proliferation is required for the induction of colitogenic IL-17-producing CD8+ T cells. J. Exp. Med. 205: 1019-1027 (2008). *
Takada K, Jameson SC. Naive T cell homeostasis: from awareness of space to a sense of place. Nat. Rev. Immunol. 9: 823-832 (2009). *
Takahashi H. New aspect of immune system: innate immunity and acquired immunity. Kansenshogaku Zasshi 80: 463-468 (2006).
Takahashi H, Honda H. Prediction of peptide binding to major histocompatibility complex class II molecules through use of boosted fuzzy classifier with SWEEP operator method. J. Biosci. Bioeng. 101: 137-141 (2006). *
Takatsuka N, Hasegawa A, Takamori A, Shimizu Y, Kato H, Ohashi T, Amagasa T, Masuda T, Kannagi M. Induction of IL-10- and IFN-gamma-producing T-cell responses by autoreactive T-cells expressing human T-cell leukemia virus type I Tax. Int. Immunol. 21: 1089-1100 (2009).
Takeuchi H, Wang J, Kawanokuchi J, Mitsuma N, Mizuno T, Suzumura A. Interferon-gamma induces microglial-activation-induced cell death: a hypothetical mechanism of relapse and remission in multiple sclerosis. Neurobiol. Dis. 22: 33-39 (2006).
Takizawa R, Pawankar R, Yamagishi S, Takenaka H, Yagi T. Increased expression of HLA-DR and CD86 in nasal epithelial cells in allergic rhinitics: antigen presentation to T cells and up-regulation by diesel exhaust particles. Clin. Exp. Allergy 37: 420-433 (2007). *
Tamai H, Matsubayashi S, Kimura A. The linkage of the major histocompatibility complex to autoimmune thyroid diseases. Nippon Rinsho 57: 1710-1715 (1999).
Tamaki S, Kawakami M, Yamanaka Y, Imai Y, Kawashima W, Yamamoto K, Kasuda S, Hatake K, Kirita T. MICA gene polymorphism not associated with nonsyndromic cleft lip with or without cleft palate in the Japanese population? Genet. Test. Mol. Biomarkers 13: 445-448 (2009).
Tamiolakis D, Nicolaidou S, Bolioti S, Tzilivaki A. Prognostic significance of major histocompatibility complex class II antigens (HLA-DR) in normal colonic mucosa, tubulovillous adenoma, and invasive colonic carcinoma. Ann. Saudi Med. 26: 133-137 (2006).
Tamiya G, Ota M, Katsuyama Y, Shiina T, Oka A, Makino S, Kimura M, Inoko H. Twenty-six new polymorphic microsatellite markers around the HLA-B, -C and -E loci in the human MHC class I region. Tissue Antigens 51: 337-346 (1998).
Tamiya G, Shiina T, Oka A, Tomizawa M, Ota M, Katsuyama Y, Yoshitome M, Makino S, Kimura M, Inoko H. New polymorphic microsatellite markers in the human MHC class I region. Tissue Antigens 54: 221-228 (1999).
Tan P, Kropshofer H, Mandelboim O, Bulbuc N, Hammerling GJ, Momburg F. Recruitment of MHC class I molecules by tapasin into the transporter associated with antigen processing-associated complex is essential for optimal peptide loading. J. Immunol. 168: 1950-1960 (2002). *
Tan PH, Yates JB, Xue SA, Chan C, Jordan WJ, Harper JE, Watson MP, Dong R, Ritter MA, Lechler RI, Lombardi G, George AJ. Creation of tolerogenic human DC via intracellular CTLA4: a novel strategy with potential in clinical immunosuppression. Blood 106: 2936-2943 (2005). *
Tanaka A. Genetic background of primary biliary cirrhosis. Hepatol. Res. 37 Suppl. 3: S377-S383 (2007). *
Tanaka A, Borchers AT, Ishibashi H, Ansari AA, Keen CL, Gershwin ME. Genetic and familial considerations of primary biliary cirrhosis. Am. J. Gastroenterol. 96: 8-15 (2001). *
Tanaka A, Lindor K, Gish R, Batts K, Shiratori Y, Omata M, Nelson JL, Ansari A, Coppel R, Newsome M, Gershwin ME. Fetal microchimerism alone does not contribute to the induction of primary biliary cirrhosis. Hepatology 30: 833-838 (1999). *
Tanaka H, Makino Y, Miura T, Hirano F, Okamoto K, Komura K, Sato Y, Makino I. Ligand-independent activation of the glucocorticoid receptor by ursodeoxycholic acid. Repression of IFN-gamma-induced MHC class II gene expression via a glucocorticoid receptor-dependent pathway. J. Immunol. 156: 1601-1608 (1996).
Tanaka M, Krutzik SR, Sieling PA, Lee DJ, Rea TH, Modlin RL. Activation of FcgammaRI on monocytes triggers differentiation into immature dendritic cells that induce autoreactive T cell responses. J. Immunol. 183: 2349-2355 (2009).
Tanaka-Takahashi Y, Yasunami M, Naruse T, Hinohara K, Matano T, Mori K, Miyazawa M, Honda M, Yasutomi Y, Nagai Y, Kimura A. Reference strand-mediated conformation analysis-based typing of multiple alleles in the rhesus macaque MHC class I Mamu-A and Mamu-B loci. Electrophoresis 28: 918-924 (2007). *
Taneja V, David CS. Spontaneous autoimmune myocarditis and cardiomyopathy in HLA-DQ8.NODAbo transgenic mice. J. Autoimmun. 33: 260-269 (2009).
Taneja V, Krco CJ, Behrens MD, Luthra HS, Griffiths MM, David CS. B cells are important as antigen presenting cells for induction of MHC-restricted arthritis in transgenic mice. Mol. Immunol. 44: 2988-2996 (2007). *
Tang ST, Wang M, Lamberth K, Harndahl M, Dziegiel MH, Claesson MH, Buus S, Lund O. MHC-I-restricted epitopes conserved among variola and other related orthopoxviruses are recognized by T cells 30 years after vaccination. Arch. Virol. 153: 1833-1844 (2008).
Tang W, Zhou R, Yang Y, Li YC, Yang YF, Zuo JP. Suppression of (5R)-5-hydroxytriptolide (LLDT-8) on allograft rejection in full MHC-mismatched mouse cardiac transplantation. Transplantation 81: 927-933 (2006).
Tang X, Maricic I, Kumar V. Anti-TCR antibody treatment activates a novel population of nonintestinal CD8alphaalpha+TCRalphabeta+ regulatory T cells and prevents experimental autoimmune encephalomyelitis. J. Immunol. 178: 6043-6050 (2007). *
Tang Y, Desierto MJ, Chen J, Young NS. The role of the Th1 transcription factor T-bet in a mouse model of immune-mediated bone marrow failure. Blood Nov 10 [Epub ahead of print] (2009). *
Tao J, Zhang XP, Chen XP, Li Y, Liu YQ, Tian J, Huang CZ, Shen GX, Tu YT. Local expression of TAP-1 and MHC-I molecules and their relationship in condyloma acuminatum. Clin. Exp. Dermatol. 32: 550-555 (2007). *
Tarasenko T, Kole HK, Bolland S. A lupus-suppressor BALB/c locus restricts IgG2 autoantibodies without altering intrinsic B cell-tolerance mechanisms. J. Immunol. 180: 3807-3814 (2008). *
Tarleton RL. Immune system recognition of Trypanosoma cruzi. Curr. Opin. Immunol. 19: 430-434 (2007).
Tartz S, Kamanova J, Simsova M, Sebo P, Bolte S, Heussler V, Fleischer B, Jacobs T. Immunization with a circumsporozoite epitope fused to Bordetella pertussis adenylate cyclase in conjunction with cytotoxic T-lymphocyte-associated antigen 4 blockade confers protection against Plasmodium berghei liver-stage malaria. Infect. Immun. 74: 2277-2285 (2006). *
Taruishi M, Yoshimatsu K, Araki K, Okumura M, Nakamura I, Kajino K, Arikawa J. Analysis of the immune response of Hantaan virus nucleocapsid protein-specific CD8(+) T cells in mice. Virology 365: 292-301 (2007). *
Tashiro-Yamaji J, Kubota T, Yoshida R. Macrophage MHC receptor 2: a novel receptor on allograft (H-2D(d)K(d))-induced macrophage (H-2D(b)K(b)) recognizing an MHC class I molecule, H-2K(d), in mice. Gene 384: 1-8 (2006). *
Tassi I, Klesney-Tait J, Colonna M. Dissecting natural killer cell activation pathways through analysis of genetic mutations in human and mouse. Immunol. Rev. 214: 92-105 (2006). *
Tay GK, Hui J, Gaudieri S, Schmitt-Egenolf M, Martinez OP, Leelayuwat C, Williamson JF, Eiermann TH, Dawkins RL. PERB11 (MIC): a polymorphic MHC gene is expressed in skin and single nucleotide polymorphisms are associated with psoriasis. Clin. Exp. Immunol. 119: 553-558 (2000). *
Taylor KE, Criswell LA. Conditional analysis of the major histocompatibility complex in rheumatoid arthritis. BMC Proc. 3 Suppl. 7: S36 (2009). *
Taylor M, Hussain A, Urayama K, Chokkalingam A, Thompson P, Trachtenberg E, Buffler P. The human major histocompatibility complex and childhood leukemia: an etiological hypothesis based on molecular mimicry. Blood Cells Mol. Dis. 42: 129-135 (2009).
Tazi Ahnini R, Camp NJ, Cork MJ, Mee JB, Keohane SG, Duff GW, di Giovine FS. Novel genetic association between the corneodesmosin (MHC S) gene and susceptibility to psoriasis. Hum. Mol. Genet. 8: 1135-1140 (1999). *
Tazi-Ahnini R, Cork MJ, Wengraf D, Wilson AG, Gawkrodger DJ, Birch MP, Messenger AG, McDonagh AJ. Notch4, a non-HLA gene in the MHC is strongly associated with the most severe form of alopecia areata. Hum. Genet. 112: 400-403 (2003). *
Tellam J, Fogg MH, Rist M, Connolly G, Tscharke D, Webb N, Heslop L, Wang F, Khanna R. Influence of translation efficiency of homologous viral proteins on the endogenous presentation of CD8+ T cell epitopes. J. Exp. Med. 204: 525-532 (2007). *
Tellam J, Smith C, Rist M, Webb N, Cooper L, Vuocolo T, Connolly G, Tscharke DC, Devoy MP, Khanna R. Regulation of protein translation through mRNA structure influences MHC class I loading and T cell recognition. Proc. Natl. Acad. Sci. U.S.A. 105: 9319-9324 (2008). *
Teller K, Budhai L, Zhang M, Haramati N, Keiser HD, Davidson A. HLA-DRB1 and DQB typing of Hispanic American patients with rheumatoid arthritis: the "shared epitope" hypothesis may not apply. J. Rheumatol. 23: 1363-1368 (1996).
Tellier J, van Meerwijk JP, Romagnoli P. An MHC-linked locus modulates thymic differentiation of CD4+CD25+Foxp3+ regulatory T lymphocytes. Int. Immunol. 18: 1509-1519 (2006). *
Temme S, Eis-Hubinger AM, McLellan AD, Koch N. The herpes simplex virus-1 encoded glycoprotein B diverts HLA-DR into the exosome pathway. J. Immunol. 184: 236-243 (2010).
Tennant LM, Renard C, Chardon P, Powell PP. Regulation of porcine classical and nonclassical MHC class I expression. Immunogenetics 59: 377-389 (2007). *
Terabe M, Berzofsky JA. The contrasting roles of NKT cells in tumor immunity. Curr. Mol. Med. 9: 667-672 (2009).
Terabe M, Berzofsky JA. Chapter 8. The role of NKT cells in tumor immunity. Adv. Cancer Res. 101C: 277-348 (2008).
Tesar BM, Zhang J, Li Q, Goldstein DR. TH1 immune responses to fully MHC mismatched allografts are diminished in the absence of MyD88, a Toll-like receptor signal adaptor protein. Am. J. Transplant. 4: 1429-1439 (2004). *
Teutsch SM, Bennetts BH, Buhler MM, Heard RN, Stewart GJ. The DRB1 Val86/Val86 genotype associates with multiple sclerosis in Australian patients. Hum. Immunol. 60: 715-722 (1999).
Tewari MK, Sinnathamby G, Rajagopal D, Eisenlohr LC. A cytosolic pathway for MHC class II-restricted antigen processing that is proteasome and TAP dependent. Nat. Immunol. 6: 287-294 (2005). *
Textoris-Taube K, Henklein P, Pollmann S, Bergann T, Weisshoff H, Seifert U, Drung I, Mugge C, Sijts A, Kloetzel PM, Kuckelkorn U. The N-terminal flanking region of the TRP2360-368 melanoma antigen determines proteasome activator PA28 requirement for epitope liberation. J. Biol. Chem. 282: 12749-12754 (2007). *
Teyton L. The saga of MHC-bound peptides: a renaissance for antigen presentation? J. Clin. Invest. 117: 3164-3166 (2007). *
Thammavongsa V, Schaefer M, Filzen T, Collins KL, Carrington M, Bangia N, Raghavan M. Assembly and intracellular trafficking of HLA-B*3501 and HLA-B*3503. Immunogenetics Oct 17 [Epub ahead of print] (2009). *
The Australo-Anglo-American Spondyloarthritis Consortium (TASC); Reveille JD, Sims AM, Danoy P, Evans DM, Leo P, Pointon JJ, Jin R, Zhou X, Bradbury LA, Appleton LH, Davis JC, Diekman L, Doan T, Dowling A, Duan R, Duncan EL, et al. Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci. Nat. Genet. Jan 10 [Epub ahead of print] (2010). *
The Games Collaborative Group. Linkage disequilibrium screening for multiple sclerosis implicates JAG1 and POU2AF1 as susceptibility genes in Europeans. J. Neuroimmunol. 179: 108-116 (2006).
The MHC Sequencing Consortium. Complete sequence and gene map of a human major histocompatibility complex. Nature 401: 921-923 (1999). *
Thedrez A, Sabourin C, Gertner J, Devilder MC, Allain-Maillet S, Fournie JJ, Scotet E, Bonneville M. Self/non-self discrimination by human gammadelta T cells: simple solutions for a complex issue? Immunol. Rev. 215: 123-135 (2007). *
Theil DJ, Libbey JE, Rodriguez F, Whitton JL, Tsunoda I, Derfuss TJ, Fujinami RS. Targeting myelin proteolipid protein to the MHC class I pathway by ubiquitination modulates the course of experimental autoimmune encephalomyelitis. J. Neuroimmunol. 204: 92-100 (2008).
Thibaudin D, Thibaudin L, Berthoux P, Mariat C, Filippis JP, Laurent B, Alamartine E, Berthoux F. TNFA2 and d2 alleles of the tumor necrosis factor alpha gene polymorphism are associated with onset/occurrence of idiopathic membranous nephropathy. Kidney Int. 71: 431-437 (2007). *
Thibodeau J, Labrecque N, Denis F, Huber BT, Sekaly RP. Binding sites for bacterial and endogenous retroviral superantigens can be dissociated on major histocompatibility complex class II molecules. J. Exp. Med. 179: 1029-1034 (1994). *
Thiele AT, Sumpter TL, Walker JA, Xu Q, Chang CH, Bacallao RL, Kher R, Wilkes DS. Pulmonary immunity to viral infection: adenovirus infection of lung dendritic cells renders T cells nonresponsive to interleukin-2. J. Virol. 80: 1826-1836 (2006). *
Thieu VT, Nguyen ET, McCarthy BP, Bruns HA, Kapur R, Chang CH, Kaplan MH. IL-4-stimulated NF-kappaB activity is required for Stat6 DNA binding. J. Leukoc. Biol. 82: 370-379 (2007). *
Thilo C, Berglund P, Applequist SE, Yewdell JW, Ljunggren HG, Achour A. Dissection of the interaction of the human cytomegalovirus-derived US2 protein with MHC class I molecules: prominent role of a single arginine residue in HLA-A2. J. Biol. Chem. 281: 8950-8957 (2006). *
Thirdborough SM, Roddick JS, Radcliffe JN, Howarth M, Stevenson FK, Elliott T. Tapasin shapes immunodominance hierarchies according to the kinetic stability of peptide - MHC class I complexes. Eur. J. Immunol. 38: 364-369 (2008). *
Thomas PB, Samant DM, Zhu Z, Selvam S, Stevenson D, Wang Y, Song SW, Mircheff AK, Schechter JE, Yiu SC, Trousdale MD. Long-term topical cyclosporine treatment improves tear production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoadenitis. J. Ocul. Pharmacol. Ther. 25: 285-292 (2009).
Thomaz Maia MH, de Lima Peixoto R, Silva de Lima CP, Magalhaes M, Sena L, do Socorro Silva Costa P, Brasil Barbosa F, de Oliveira LF, Romero M, Nogueira de Araujo Silva C, Melo Dos Santos EJ. Predisposition to idiopathic thrombocytopenic purpura maps close to the MICA gene. Hum. Immunol. Jan 23 [Epub ahead of print] (2009).
Thompson JS, Chu Y, Glass JF, Brown SA. Absence of IL-23p19 in donor allogeneic cells reduces mortality from acute GVHD. Bone Marrow Transplant. Aug 31 [Epub ahead of print] (2009).
Thompson PD, Hsieh JC, Whitfield GK, Haussler CA, Jurutka PW, Galligan MA, Tillman JB, Spindler SR, Haussler MR. Vitamin D receptor displays DNA binding and transactivation as a heterodimer with the retinoid X receptor, but not with the thyroid hormone receptor. J. Cell. Biochem. 75: 462-480 (1999). *
Thomson CW, Lee BP, Zhang L. Double-negative regulatory T cells: non-conventional regulators. Immunol. Res. 35: 163-178 (2006). *
Thomson G. HLA disease associations: models for the study of complex human genetic disorders. Crit. Rev. Clin. Lab. Sci. 32: 183-219 (1995).
Thorsby E. A short history of HLA. Tissue Antigens 74: 101-116 (2009). *
Thurau SR, Diedrichs-Mohring M, Fricke H, Arbogast S, Wildner G. Molecular mimicry as a therapeutic approach for an autoimmune disease: oral treatment of uveitis-patients with an MHC-peptide crossreactive with autoantigen - first results. Immunol. Lett. 57: 193-201 (1997).
Tian C, Ansari MJ, Paez-Cortez J, Bagley J, Godwin J, Donnarumma M, Sayegh MH, Iacomini J. Induction of robust diabetes resistance and prevention of recurrent type 1 diabetes following islet transplantation by gene therapy. J. Immunol. 179: 6762-6769 (2007). *
Tian C, Bagley J, Cretin N, Seth N, Wucherpfennig KW, Iacomini J. Prevention of type 1 diabetes by gene therapy. J. Clin. Invest. 114: 969-978 (2004). *
Tian W, Boggs DA, Ding WZ, Chen DF, Fraser PA. MICA genetic polymorphism and linkage disequilibrium with HLA-B in 29 African-American families. Immunogenetics 53: 724-728 (2001).
Tian W, Boggs DA, Uko G, Essiet A, Inyama M, Banjoko B, Adewole T, Ding WZ, Mohseni M, Fritz R, Chen DF, Palmer LJ, Fraser PA. MICA, HLA-B haplotypic variation in five population groups of sub-Saharan African ancestry. Genes Immun. 4: 500-505 (2003). *
Tian W, Cai J, Wang F, Li L. MICA polymorphism in a northern Chinese Han population: the identification of a new MICA allele, MICA*059. Hum. Immunol. Jan 21 [Epub ahead of print] (2010).
Tian W, Li LX, Wang F, Luo QZ, Yan MY, Yu P, Guo SS, Cao Y. MICA-STR, HLA-B haplotypic diversity and linkage disequilibrium in the Hunan Han population of southern China. Int. J. Immunogenet. 33: 241-245 (2006). *
Tian W, Wang F, Cai JH, Li LX. Polymorphic insertions in 5 Alu loci within the major histocompatibility complex class I region and their linkage disequilibria with HLA alleles in four distinct populations in mainland China. Tissue Antigens 72: 559-567 (2008). *
Tiao MM, Lu L, Huang LT, Liang CD, Chen CL, Tao R, Fung JJ, Qian S. Cross-tolerance of recipient-derived transforming growth factor-beta dendritic cells. Transplant. Proc. 39: 281-282 (2007). *
Tiede A, Eisert R, Czwalinna A, Miesbach W, Scharrer I, Ganser A. Acquired haemophilia caused by non-haemophilic factor VIII gene variants. Ann. Hematol. Jan 7 [Epub ahead of print] (2010).
Tiegs G, Lohse AW. Immune tolerance: what is unique about the liver. J. Autoimmun. Aug 28 [Epub ahead of print] (2009).
Tiercy JM, Jeannet M, Mach B. A new HLA-DRB1 allele within the DRw52 supertypic specificity (DRw13-DwHAG): sequencing and direct identification by oligonucleotide typing. Eur. J. Immunol. 20: 237-241 (1990).
Tighe MR, Hall MA, Ashkenazi A, Siegler E, Lanchbury JS, Ciclitira PJ. Celiac disease among Ashkenazi Jews from Israel. A study of the HLA class II alleles and their associations with disease susceptibility. Hum. Immunol. 38: 270-276 (1993).
Tighe MR, Hall MA, Cardi E, Ashkenazi A, Lanchbury JS, Ciclitira PJ. Associations between alleles of the major histocompatibility complex-encoded ABC transporter gene TAP2, HLA class II alleles, and celiac disease susceptibility. Hum. Immunol. 39: 9-16 (1994).
Ting YT, Temme S, Koch N, McLellan AD. A new monoclonal antibody recognizing a linear determinant on the HLA-DRalpha chain N-terminus. Hybridoma (Larchmt.) 28: 423-429 (2009).
Tinto N, Ciacci C, Calcagno G, Gennarelli D, Spampanato A, Farinaro E, Tortora R, Sacchetti L. Increased prevalence of celiac disease without gastrointestinal symptoms in adults MICA 5.1 homozygous subjects from the Campania area. Dig. Liver Dis. 40: 248-252 (2008).
Tirlapur UK, Mulholland WJ, Bellhouse BJ, Kendall M, Cornhill JF, Cui Z. Femtosecond two-photon high-resolution 3D imaging, spatial-volume rendering and microspectral characterization of immunolocalized MHC-II and mLangerin/CD207 antigens in the mouse epidermis. Microsc. Res. Tech. 69: 767-775 (2006). *
Tirouvanziam R, Gernez Y, Conrad CK, Moss RB, Schrijver I, Dunn CE, Davies ZA, Herzenberg LA, Herzenberg LA. Profound functional and signaling changes in viable inflammatory neutrophils homing to cystic fibrosis airways. Proc. Natl. Acad. Sci. U.S.A. 105: 4335-4339 (2008). *
Tishon A, LaFace DM, Lewicki H, van Binnendijk RS, Osterhaus A, Oldstone MB. Transgenic mice expressing human HLA and CD8 molecules generate HLA-restricted measles virus cytotoxic T lymphocytes of the same specificity as humans with natural measles virus infection. Virology 275: 286-293 (2000). *
Tjandra K, Sharkey KA, Swain MG. Progressive development of a Th1-type hepatic cytokine profile in rats with experimental cholangitis. Hepatology 31: 280-290 (2000). *
Tlaskalova-Hogenova H, Farre-Castany MA, Stepankova R, Kozakova H, Tuckova L, Funda DP, Barot R, Cukrowska B, Sinkora J, Mandel L, et al. The gut as a lymphoepithelial organ: the role of intestinal epithelial cells in mucosal immunity. Folia. Microbiol. (Praha.) 40: 385-391 (1995).
To K, Agrotis A, Besra G, Bobik A, Toh BH. NKT cell subsets mediate differential proatherogenic effects in ApoE-/- mice. Arterioscler. Thromb. Vasc. Biol. 29: 671-677 (2009).
Todd JA. Genetics of type 1 diabetes. Pathol. Biol. (Paris) 45: 219-227 (1997).
Todd JA, Farrall M. Panning for gold: genome-wide scanning for linkage in type 1 diabetes. Hum. Mol. Genet. 5: S1443-S1448 (1996).
Toebes M, Coccoris M, Bins A, Rodenko B, Gomez R, Nieuwkoop NJ, van de Kasteele W, Rimmelzwaan GF, Haanen JB, Ovaa H, Schumacher TN. Design and use of conditional MHC class I ligands. Nat. Med. 12: 246-251 (2006). *
Togun RA, Resetkova E, Kawai K, Enomoto T, Volpe R. Activation of CD8+ T lymphocytes in insulin-dependent diabetes mellitus. Clin. Immunol. Immunopathol. 82: 243-249 (1997). *
Tolar P, Sohn HW, Pierce SK. Viewing the antigen-induced initiation of B-cell activation in living cells. Immunol. Rev. 221: 64-76 (2008). *
Tomer Y, Huber A. The etiology of autoimmune thyroid disease: a story of genes and environment. J. Autoimmun. 32: 231-239 (2009).
Tonelli LH, Postolache TT. Tumor necrosis factor alpha, interleukin-1 beta, interleukin-6 and major histocompatibility complex molecules in the normal brain and after peripheral immune challenge. Neurol. Res. 27: 679-684 (2005).
Tonelli LH, Postolache TT, Sternberg EM. Inflammatory genes and neural activity: involvement of immune genes in synaptic function and behavior. Front. Biosci. 10: 675-680 (2005).
Tong JC, Kong L, Tan TW, Ranganathan S. MPID-T: database for sequence-structure-function information on T-cell receptor/peptide/MHC interactions. Appl. Bioinformatics 5: 111-114 (2006).
Tong JC, Tan TW, Sinha AA, Ranganathan S. Prediction of desmoglein-3 peptides reveals multiple shared T-cell epitopes in HLA DR4- and DR6- associated pemphigus vulgaris. BMC Bioinformatics 7 Suppl. 5: S7 (2006). *
Torii H, Nakagawa H, Ishibashi Y, Tokunaga K, Juji T. Genetic polymorphisms in HLA-A, -B, -C and -DR antigens in Japanese patients with palmoplantar pustulosis. Dermatology 188: 290-292 (1994).
Torn C, Gupta M, Nikitina Zake L, Sanjeevi CB, Landin-Olsson M. Heterozygosity for MICA5.0/MICA5.1 and HLA-DR3-DQ2/DR4-DQ8 are independent genetic risk factors for latent autoimmune diabetes in adults. Hum. Immunol. 64: 902-909 (2003).
Torn C, Gupta M, Sanjeevi CB, Aberg A, Frid A, Landin-Olsson M. Different HLA-DR-DQ and MHC class I chain-related gene A (MICA) genotypes in autoimmune and nonautoimmune gestational diabetes in a Swedish population. Hum. Immunol. 65: 1443-1450 (2004).
Torres BA, Griggs ND, Johnson HM. Bacterial and retroviral superantigens share a common binding region on class II MHC antigens. Nature 364: 152-154 (1993). *
Torres M, Ramachandra L, Rojas RE, Bobadilla K, Thomas J, Canaday DH, Harding CV, Boom WH. Role of phagosomes and major histocompatibility complex class II (MHC-II) compartment in MHC-II antigen processing of Mycobacterium tuberculosis in human macrophages. Infect. Immun. 74: 1621-1630 (2006). *
Torres MI, Le Discorde M, Lorite P, Rios A, Gassull MA, Gil A, Maldonado J, Dausset J, Carosella ED. Expression of HLA-G in inflammatory bowel disease provides a potential way to distinguish between ulcerative colitis and Crohn's disease. Int. Immunol. 16: 579-583 (2004). *
Torres MI, Lopez-Casado MA, Luque J, Pena J, Rios A. New advances in coeliac disease: serum and intestinal expression of HLA-G. Int. Immunol. 18: 713-718 (2006). *
Toseland CP, Clayton DJ, McSparron H, Hemsley SL, Blythe MJ, Paine K, Doytchinova IA, Guan P, Hattotuwagama CK, Flower DR. AntiJen: a quantitative immunology database integrating functional, thermodynamic, kinetic, biophysical, and cellular data. Immunome Res. 1: 4 (2005). *
Toth EK, Kocsis J, Madaras B, Biro A, Pocsai Z, Fust G, Blasko B, Karadi I, Adany R, Laki J. The 8.1 ancestral MHC haplotype is strongly associated with colorectal cancer risk. Int. J. Cancer 121: 1744-1748 (2007). *
Traherne JA. Human MHC architecture and evolution: implications for disease association studies. Int. J. Immunogenet. 35: 179-192 (2008). *
Traherne JA, Barcellos LF, Sawcer SJ, Compston DA, Ramsay PP, Hauser SL, Oksenberg JR, Trowsdale J. Association of the truncating splice site mutation in BTNL2 with multiple sclerosis is secondary to HLA-DRB1*15. Hum. Mol. Genet. 15: 155-161 (2006). *
Traherne JA, Horton R, Roberts AN, Miretti MM, Hurles ME, Stewart CA, Ashurst JL, Atrazhev AM, Coggill P, Palmer S, Almeida J, Sims S, Wilming LG, Rogers J, de Jong PJ, Carrington M, Elliott JF, Sawcer S, Todd JA, Trowsdale J, Beck S. Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history. PLoS Genet. 2: e9 (2006). *
Tran CN, Davis MJ, Tesmer LA, Endres JL, Motyl CD, Smuda C, Somers EC, Chung KC, Urquhart AG, Lundy SK, Kovats S, Fox DA. Presentation of arthritogenic peptide to antigen-specific T cells by fibroblast-like synoviocytes. Arthritis Rheum. 56: 1497-1506 (2007). *
Trautwein C, Gerken G, Lohr H, Meyer zum Buschenfelde KH, Manns M. Lack of surface expression for the B-cell autoepitope of cytochrome P450 IID6 evidenced by flow cytometry. Z. Gastroenterol. 31: 225-230 (1993).
Treanor B, Lanigan PM, Kumar S, Dunsby C, Munro I, Auksorius E, Culley FJ, Purbhoo MA, Phillips D, Neil MA, Burshtyn DN, French PM, Davis DM. Microclusters of inhibitory killer immunoglobulin-like receptor signaling at natural killer cell immunological synapses. J. Cell Biol. 174: 153-161 (2006). *
Trejdosiewicz LK, Badr-el-Din S, Smart CJ, Malizia G, Oakes DJ, Heatley RV, Losowsky MS. Colonic mucosal T lymphocytes in ulcerative colitis: expression of CD7 antigen in relation to MHC class II (HLA-D) antigens. Dig. Dis. Sci. 34: 1449-1456 (1989).
Trgovcich J, Cebulla C, Zimmerman P, Sedmak DD. Human cytomegalovirus protein pp71 disrupts major histocompatibility complex class I cell surface expression. J. Virol. 80: 951-963 (2006). *
Trikudanathan S, Sayegh MH. The evolution of the immunobiology of co-stimulatory pathways: clinical implications. Clin. Exp. Rheumatol. 25: S12-S21 (2007).
Tripathi S, Bruch D, Kittur DS. Ginger extract inhibits LPS induced macrophage activation and function. BMC Complement. Altern. Med. 8: 1 (2008). *
Trivedi VB, Dave AP, Dave JM, Patel BC. Human leukocyte antigen and its role in transplantation biology. Transplant. Proc. 39: 688-693 (2007). *
Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu. Rev. Immunol. 23: 975-1028 (2005). *
Tron F, Gilbert D, Joly P, Mouquet H, Drouot L, Ayed MB, Sellami M, Masmoudi H, Makni S. Immunogenetics of pemphigus: an update. Autoimmunity 39: 531-539 (2006).
Tron F, Gilbert D, Mouquet H, Joly P, Drouot L, Makni S, Masmoudi H, Charron D, Zitouni M, Loiseau P, Ben Ayed M. Genetic factors in pemphigus. J. Autoimmun. 24: 319-328 (2005).
Trost M, English L, Lemieux S, Courcelles M, Desjardins M, Thibault P. The phagosomal proteome in interferon-gamma-activated macrophages. Immunity 30: 143-154 (2009). *
Trowsdale J, Barten R, Haude A, Stewart CA, Beck S, Wilson MJ. The genomic context of natural killer receptor extended gene families. Immunol. Rev. 181: 20-38 (2001). *
Trowsdale J, Moffett A. NK receptor interactions with MHC class I molecules in pregnancy. Semin. Immunol. 20: 317-320 (2008). *
Trucco M. Is facilitating pancreatic beta cell regeneration a valid option for clinical therapy? Cell. Transplant. 15 Suppl. 1: S75-S84 (2006).
Trueb M. Autoimmune-associated MHC class II molecules. Hautarzt. 46: 225-227 (1995).
Truedsson L, Sturfelt G, Johansen P, Nived O, Thuresson B. Sharing of MHC haplotypes among patients with systemic lupus erythematosus from unrelated Caucasian multicase families: disease association with the extended haplotype [HLA-B8, SC01, DR17] J. Rheumatol. 22: 1852-1861 (1995).
Trunecka P. Immunological mechanisms of liver allograft rejection. Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 44-46. September 12 - 13 (2003). *
Truong P, Heydari S, Garidou L, McGavern DB. Persistent viral infection elevates central nervous system MHC class I through chronic production of interferons. J. Immunol. 183: 3895-3905 (2009).
Truong W, Plester JC, Hancock WW, Kaye J, Merani S, Murphy KM, Murphy TL, Anderson CC, Shapiro AM. Negative and positive co-signaling with anti-BTLA (PJ196) and CTLA4Ig prolongs islet allograft survival. Transplantation 84: 1368-1372 (2007).
Truong W, Plester JC, Hancock WW, Merani S, Murphy TL, Murphy KM, Kaye J, Anderson CC, Shapiro AM. Combined coinhibitory and costimulatory modulation with anti-BTLA and CTLA4ig facilitates tolerance in murine islet allografts. Am. J. Transplant. 7: 2663-2674 (2007). *
Truscott SM, Wang X, Lybarger L, Biddison WE, McBerry C, Martinko JM, Connolly JM, Linette GP, Fremont DH, Hansen TH, Carreno BM. Human MHC class I molecules with disulfide traps secure disease-related antigenic peptides and exclude competitor peptides. J. Biol. Chem. 283: 7480-7490 (2008). *
Tsai YC, Hsieh HJ, Liao F, Ni CW, Chao YJ, Hsieh CY, Wang DL. Laminar flow attenuates interferon-induced inflammatory responses in endothelial cells. Cardiovasc. Res. 74: 497-505 (2007). *
Tsan MF, Gao B. Heat shock proteins and immune system. J. Leukoc. Biol. 85: 905-910 (2009). *
Tsao BP. Update on human systemic lupus erythematosus genetics. Curr. Opin. Rheumatol. 16: 513-521 (2004).
Tsao BP, Cantor RM, Kalunian KC, Chen CJ, Badsha H, Singh R, Wallace DJ, Kitridou RC, Chen SL, Shen N, Song YW, Isenberg DA, Yu CL, Hahn BH, Rotter JI. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J. Clin. Invest. 99: 725-731 (1997). *
Tsao BP, Grossman JM. Genetics and systemic lupus erythematosus. Curr. Rheumatol. Rep. 3: 183-190 (2001).
Tsao GJ, Allen JA, Logronio KA, Lazzeroni LC, Shizuru JA. Purified hematopoietic stem cell allografts reconstitute immunity superior to bone marrow. Proc. Natl. Acad. Sci. U.S.A. 106: 3288-3293 (2009). *
Tsatsanis C, Vaporidi K, Zacharioudaki V, Androulidaki A, Sykulev Y, Margioris AN, Tsichlis PN. Tpl2 and ERK transduce antiproliferative T cell receptor signals and inhibit transformation of chronically stimulated T cells. Proc. Natl. Acad. Sci. U.S.A. 105: 2987-2992 (2008). *
Tseng SY, Liu M, Dustin ML. CD80 cytoplasmic domain controls localization of CD28, CTLA-4, and protein kinase C{theta} in the immunological synapse. J. Immunol. 175: 7829-7836 (2005). *
Tseng YT, Lee HH, Lee YJ. An investigation of the C4 gene arrangement in ethnic Chinese (Taiwanese). Int. J. Immunogenet. 35: 323-329 (2008).
Tso HW, Ip WK, Chong WP, Tam CM, Chiang AK, Lau YL. Association of interferon gamma and interleukin 10 genes with tuberculosis in Hong Kong Chinese. Genes Immun. 6: 358-363 (2005). *
Tsory S, Kellman-Pressman S, Fishman D, Segal S. Reconstitution of expression of H-2K region-encoded murine MHC class I glycoproteins in MHC class I-deficient B16BL6 melanoma cells affects the expression and function of antigen-processing machinery. Immunol. Lett. 102: 237-240 (2006).
Tsui H, Chan Y, Tang L, Winer S, Cheung RK, Paltser G, Selvanantham T, Elford AR, Ellis JR, Becker DJ, Ohashi PS, Dosch HM. Targeting of pancreatic glia in type 1 diabetes. Diabetes 57: 918-928 (2008). *
Tsuji K, Watanabe Y, Van De Water J, Nakanishi T, Kajiyama G, Parikh-Patel A, Coppel R, Gershwin ME. Familial primary biliary cirrhosis in Hiroshima. J. Autoimmun. 13: 171-178 (1999). *
Tsuneyama K, Van de Water J, Leung PS, Cha S, Nakanuma Y, Kaplan M, De Lellis R, Coppel R, Ansari A, Gershwin ME. Abnormal expression of the E2 component of the pyruvate dehydrogenase complex on the luminal surface of biliary epithelium occurs before major histocompatibility complex class II and BB1/B7 expression. Hepatology 21: 1031-1037 (1995).
Tsuneyama K, Van De Water J, Van Thiel D, Coppel R, Ruebner B, Nakanuma Y, Dickson ER, Gershwin ME. Abnormal expression of PDC-E2 on the apical surface of biliary epithelial cells in patients with antimitochondrial antibody-negative primary biliary cirrhosis. Hepatology 22: 1440-1446 (1995).
Tsuneyama K, Yasoshima M, Harada K, Hiramatsu K, Gershwin ME, Nakanuma Y. Increased CD1d expression on small bile duct epithelium and epithelioid granuloma in livers in primary biliary cirrhosis. Hepatology 28: 620-623 (1998). *
Tsuzuki Y, Miyazaki J, Matsuzaki K, Okada Y, Hokari R, Kawaguchi A, Nagao S, Itoh K, Miura S. Differential modulation in the functions of intestinal dendritic cells by long- and medium-chain fatty acids. J. Gastroenterol. 41: 209-216 (2006). *
Turek PJ, Grumet FC, Engleman EG. Molecular variants of the HLA-B27 antigen in healthy individuals and patients with spondylarthropathies. Immunol. Rev. 86: 71-91 (1985).
Turesson C. Endothelial expression of MHC class II molecules in autoimmune disease. Curr. Pharm. Des. 10: 129-143 (2004).
Turkcapar N, Tuncali T, Kutlay S, Burhan BY, Kinikli G, Erturk S, Duman M. The contribution of genotypes at the MICA gene triplet repeat polymorphisms and MEFV mutations to amyloidosis and course of the disease in the patients with familial Mediterranean fever. Rheumatol. Int. 27: 545-551 (2007). *
Turley DM, Miller SD. Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimental autoimmune encephalomyelitis. J. Immunol. 178: 2212-2220 (2007). *
Turnbull EL, Yrlid U, Jenkins CD, Macpherson GG. Intestinal dendritic cell subsets: differential effects of systemic TLR4 stimulation on migratory fate and activation in vivo. J. Immunol. 174: 1374-1384 (2005). *
Turner MJ, Delay ML, Bai S, Klenk E, Colbert RA. HLA-B27 up-regulation causes accumulation of misfolded heavy chains and correlates with the magnitude of the unfolded protein response in transgenic rats: implications for the pathogenesis of spondylarthritis-like disease. Arthritis Rheum. 56: 215-223 (2007). *
Tuwir I, Dunne C, Crowley J, Saddik T, Murphy R, Cassidy L. The relationship between HLA-DRB1 alleles and optic neuritis in Irish patients and the risk of developing multiple sclerosis. Br. J. Ophthalmol. 91: 1288-1292 (2007). *
Tynan FE, Borg NA, Miles JJ, Beddoe T, El-Hassen D, Silins SL, van Zuylen WJ, Purcell AW, Kjer-Nielsen L, McCluskey J, Burrows SR, Rossjohn J. The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: implications for T-cell receptor engagement and T-cell immunodominance. J. Biol. Chem. 280: 23900-23909 (2005). *
Tynan FE, Burrows SR, Buckle AM, Clements CS, Borg NA, Miles JJ, Beddoe T, Whisstock JC, Wilce MC, Silins SL, Burrows JM, Kjer-Nielsen L, Kostenko L, Purcell AW, McCluskey J, Rossjohn J. T cell receptor recognition of a 'super-bulged' major histocompatibility complex class I-bound peptide. Nat. Immunol. 6: 1114-1122 (2005). *
Tynan FE, Elhassen D, Purcell AW, Burrows JM, Borg NA, Miles JJ, Williamson NA, Green KJ, Tellam J, Kjer-Nielsen L, McCluskey J, Rossjohn J, Burrows SR. The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation. J. Exp. Med. 202: 1249-1260 (2005). *
Tynan FE, Reid HH, Kjer-Nielsen L, Miles JJ, Wilce MC, Kostenko L, Borg NA, Williamson NA, Beddoe T, Purcell AW, Burrows SR, McCluskey J, Rossjohn J. A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule. Nat. Immunol. 8: 268-276 (2007). *
Tzang BS, Tsai CC, Shi JY, Hsu TC. Up-regulation of adhesion molecule expression and induction of TNF-alpha on vascular endothelial cells by antibody against human parvovirus B19 VP1 unique region protein. Clin. Chim. Acta 395: 77-83 (2008). *
Udey MC, Peck RD, Pentland AP, Schreiner GF, Lefkowith JB. Antigen-presenting cells in essential fatty acid-deficient murine epidermis: keratinocytes bearing class II (Ia) antigens may potentiate the accessory cell function of Langerhans cells. J. Invest. Dermatol. 96: 950-958 (1991).
Udyavar A, Alli R, Nguyen P, Baker L, Geiger TL. Subtle affinity-enhancing mutations in a myelin oligodendrocyte glycoprotein-specific TCR alter specificity and generate new self-reactivity. J. Immunol. 182: 4439-4447 (2009).
Ueda R, Ohkusu-Tsukada K, Fusaki N, Soeda A, Kawase T, Kawakami Y, Toda M. Identification of HLA-A2- and A24-restricted T-cell epitopes derived from SOX6 expressed in glioma stem cells for immunotherapy. Int. J. Cancer 126: 919-929 (2009). *
Ueki S, Yamashita K, Aoyagi T, Haga S, Suzuki T, Itoh T, Taniguchi M, Shimamura T, Furukawa H, Ozaki M, Umezawa K, Todo S. Control of allograft rejection by applying a novel nuclear factor-kappaB inhibitor, dehydroxymethylepoxyquinomicin. Transplantation 82: 1720-1727 (2006).
Ueno A, Cho S, Cheng L, Wang Z, Wang B, Yang Y. Diabetes resistance/susceptibility in T cells of nonobese diabetic mice conferred by MHC and MHC-linked genes. J. Immunol. 175: 5240-5247 (2005). *
Ueno T, Habicht A, Clarkson MR, Albin MJ, Yamaura K, Boenisch O, Popoola J, Wang Y, Yagita H, Akiba H, Ansari MJ, Yang J, Turka LA, Rothstein DM, Padera RF, Najafian N, Sayegh MH. The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J. Clin. Invest. 118: 742-751 (2008). *
Uhlin M, Masucci M, Levitsky V. Is the activity of partially agonistic MHC:peptide ligands dependent on the quality of immunological help? Scand. J. Immunol. 64: 581-587 (2006). *
Ulgiati D, Abraham LJ. Comparative analysis of the disease-associated complement C4 gene from the HLA-A1, B8, DR3 haplotype. Exp. Clin. Immunogenet. 13: 43-54 (1996).
Umesaki Y, Setoyama H. Structure of the intestinal flora responsible for development of the gut immune system in a rodent model. Microbes Infect. 2: 1343-1351 (2000). *
Umesaki Y, Setoyama H, Matsumoto S, Imaoka A, Itoh K. Differential roles of segmented filamentous bacteria and clostridia in development of the intestinal immune system. Infect. Immun. 67: 3504-3511 (1999). *
Unger WW, Laban S, Kleijwegt FS, van der Slik AR, Roep BO. Induction of regulatory T cells by monocyte-derived dendritic cells modulated by vitamin D3 or dexamethasone: differential role for PD-L1. Eur. J. Immunol. 39: 3147-3159 (2009). *
Urban JA, Brugmann W, Winandy S. Cutting edge: Ikaros null thymocytes mature into the CD4 lineage with reduced TCR signal: a study using CD3zeta immunoreceptor tyrosine-based activation motif transgenic mice. J. Immunol. 182: 3955-3959 (2009).
Urcelay E, Santiago JL, de la Calle H, Mart�nez A, Figueredo A, Fernandez-Arquero M, de la Concha EG. Interleukin-10 polymorphisms in Spanish type 1 diabetes patients. Genes Immun. 5: 306-309 (2004). *
Urcelay E, Santiago JL, de la Calle H, Martinez A, Mendez J, Ibarra JM, Maluenda C, Fernandez-Arquero M, de la Concha EG. Type 1 diabetes in the Spanish population: additional factors to class II HLA-DR3 and -DR4. BMC Genomics 6: 56 (2005). *
Ureta G, Osorio F, Morales J, Rosemblatt M, Bono MR, Fierro JA. Generation of dendritic cells with regulatory properties. Transplant. Proc. 39: 633-637 (2007). *
Urosevic M. HLA-G in the skin - friend or foe? Semin. Cancer Biol. 17: 480-484 (2007). *
Usui Y, Takeuchi M, Hattori T, Okunuki Y, Nagasawa K, Kezuka T, Okumura K, Yagita H, Akiba H, Goto H. Suppression of experimental autoimmune uveoretinitis by regulatory dendritic cells in mice. Arch. Ophthalmol. 127: 514-519 (2009). *
Vaidya B, Imrie H, Geatch DR, Perros P, Ball SG, Baylis PH, Carr D, Hurel SJ, James RA, Kelly WF, Kemp EH, Young ET, Weetman AP, Kendall-Taylor P, Pearce SH. Association analysis of the cytotoxic T lymphocyte antigen-4 (CTLA-4) and autoimmune regulator-1 (AIRE-1) genes in sporadic autoimmune Addison's disease. J. Clin. Endocrinol. Metab. 85: 688-691 (2000). *
Vaidya B, Imrie H, Perros P, Young ET, Kelly WF, Carr D, Large DM, Toft AD, McCarthy MI, Kendall-Taylor P, Pearce SH. The cytotoxic T lymphocyte antigen-4 is a major Graves' disease locus. Hum. Mol. Genet. 8: 1195-1199 (1999). *
Valdes AM, Thomson G; Diabetes Genetics Consortium. Several loci in the HLA class III region are associated with T1D risk after adjusting for DRB1-DQB1. Diabetes Obes. Metab. 11 Suppl. 1: 46-52 (2009). *
Valente FP, Tan C, Phipps M, Witt CS, Kaur G, Gut I, Allcock R, Price P. TNF block haplotypes associated with conserved MHC haplotypes in European, Asian and Australian Aboriginal donors. Tissue Antigens 74: 57-61 (2009). *
Valente FP, Tan CR, Temple SE, Phipps M, Witt CS, Kaur G, Gut I, McGinn S, Allcock RJ, Chew CS, Price P. The evolution and diversity of TNF block haplotypes in European, Asian and Australian Aboriginal populations. Genes Immun. 10: 607-615 (2009). *
Vales-Gomez M, Erskine RA, Deacon MP, Strominger JL, Reyburn HT. The role of zinc in the binding of killer cell Ig-like receptors to class I MHC proteins. Proc. Natl. Acad. Sci. U.S.A. 98: 1734-1739 (2001). *
Valiante NM, Lienert K, Shilling HG, Smits BJ, Parham P. Killer cell receptors: keeping pace with MHC class I evolution. Immunol. Rev. 155: 155-164 (1997).
Valle-Rios R, Patino-Lopez G, Medina-Contreras O, Canche-Pool E, Recillas-Targa F, Lopez-Bayghen E, Zlotnik A, Ortiz-Navarrete V. Characterization of CRTAM gene promoter: AP-1 transcription factor control its expression in human T CD8 lymphocytes. Mol. Immunol. 46: 3379-3387 (2009). *
Vamosi G, Bodnar A, Damjanovich S, Nagy P, Varga Z, Damjanovich L. The role of supramolecular protein complexes and membrane potential in transmembrane signaling processes of lymphocytes. Immunol. Lett. 104: 53-58 (2006).
van Amelsfort JM, Jacobs KM, Bijlsma JW, Lafeber FP, Taams LS. CD4(+)CD25(+) regulatory T cells in rheumatoid arthritis: differences in the presence, phenotype, and function between peripheral blood and synovial fluid. Arthritis Rheum. 50: 2775-2785 (2004). *
van Belzen MJ, Vrolijk MM, Meijer JWR, Crusius JBA, Pearson PL, Sandkuijl LA, Houwen RHJ, Wijmenga C. A genomewide screen in a four-generation Dutch family with celiac disease: evidence for linkage to chromosomes 6 and 9. Am. J. Gastroenterol. 99: 466-471 (2004). *
Van Coppernolle S, Verstichel G, Timmermans F, Velghe I, Vermijlen D, De Smedt M, Leclercq G, Plum J, Taghon T, Vandekerckhove B, Kerre T. Functionally mature CD4 and CD8 TCRalphabeta cells are generated in OP9-DL1 cultures from human CD34+ hematopoietic cells. J. Immunol. 183: 4859-4870 (2009).
van de Berg PJ, van Leeuwen EM, Ten Berge IJ, van Lier R. Cytotoxic human CD4(+) T cells. Curr. Opin. Immunol. 20: 339-343 (2008).
Van de Water J, Shimoda S, Niho Y, Coppel R, Ansari A, Gershwin ME. The role of T cells in primary biliary cirrhosis. Semin. Liver Dis. 17: 105-113 (1997).
van den Berg H, Greuter M, Kraal G, den Haan JM. Different mechanisms regulate CD4(+) T cell independent induction of oral and nasal tolerance of CD8(+) T cells. Immunobiology Mar 9 [Epub ahead of print] (2009).
van den Berg HA, Rand DA. Foreignness as a matter of degree: the relative immunogenicity of peptide/MHC ligands. J. Theor. Biol. 231: 535-548 (2004). *
van den Oord JJ, Fevery J, de Groote J, Desmet VJ. Immunohistochemical characterization of inflammatory infiltrates in primary biliary cirrhosis. Liver 4: 264-274 (1984).
van der Slik AR, van den Eng I, Eerligh P, Doxiadis II, Koeleman BP, Roep BO, Giphart MJ. Sequence variation within the major histocompatibility complex subregion centromeric of HLA class II in type 1 diabetes. Tissue Antigens 69: 348-353 (2007). *
van der Veek PP, van den Berg M, de Kroon YE, Verspaget HW, Masclee AA. Role of tumor necrosis factor-a and interleukin-10 gene polymorphisms in irritable bowel syndrome. Am. J. Gastroenterol. 100: 2510-2516 (2005). *
van Duivenvoorde LM, van Mierlo GJ, Boonman ZF, Toes RE. Dendritic cells: vehicles for tolerance induction and prevention of autoimmune diseases. Immunobiology 211: 627-632 (2006).
van Endert P. Processing of MHC class I presented antigens. Med. Sci. (Paris) 22: 727-732 (2006).
Van Endert P, Hassainya Y, Lindo V, Bach JM, Blancou P, Lemonnier F, Mallone R. HLA class I epitope discovery in type 1 diabetes. Ann. N. Y. Acad. Sci. 1079: 190-197 (2006). *
van Endert PM, Lopez MT, Patel SD, Monaco JJ, McDevitt HO. Genomic polymorphism, recombination, and linkage disequilibrium in human major histocompatibility complex-encoded antigen-processing genes. Proc. Natl. Acad. Sci. U.S.A. 89: 11594-11597 (1992). *
van Endert PM, Saveanu L, Hewitt EW, Lehner P. Powering the peptide pump: TAP crosstalk with energetic nucleotides. Trends Biochem. Sci. 27: 454-461 (2002). *
van Etten E, Mathieu C. Immunoregulation by 1,25-dihydroxyvitamin D(3): basic concepts. J. Steroid Biochem. Mol. Biol. 97: 93-101 (2005).
van Hall T, Wolpert EZ, van Veelen P, Laban S, van der Veer M, Roseboom M, Bres S, Grufman P, de Ru A, Meiring H, de Jong A, Franken K, Teixeira A, Valentijn R, Drijfhout JW, Koning F, Camps M, Ossendorp F, Karre K, Ljunggren HG, Melief CJ, Offringa R. Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants. Nat. Med. 12: 417-424 (2006). *
Van Kaer L. NKT cells: T lymphocytes with innate effector functions. Curr. Opin. Immunol. 19: 354-364 (2007). *
Van Kaer L. Regulation of immune responses by CD1d-restricted natural killer T cells. Immunol. Res. 30: 139-153 (2004). *
van Kooyk Y. C-type lectins on dendritic cells: key modulators for the induction of immune responses. Biochem. Soc. Trans. 36: 1478-1481 (2008). *
van Leeuwen EM, Sprent J, Surh CD. Generation and maintenance of memory CD4(+) T Cells. Curr. Opin. Immunol. 21: 167-172 (2009).
van Lith M, van Ham M, Neefjes J. Novel polymorphisms in HLA-DOA and HLA-DOB in B-cell malignancies. Immunogenetics 54: 591-595 (2002). *
Van Montfrans C, Hooijberg E, Rodriguez Pena MS, De Jong EC, Spits H, Te Velde AA, Van Deventer SJ. Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer. Gastroenterology 123: 1877-1888 (2002). *
van Niel G, Wubbolts R, Ten Broeke T, Buschow SI, Ossendorp FA, Melief CJ, Raposo G, van Balkom BW, Stoorvogel W. Dendritic cells regulate exposure of MHC class II at their plasma membrane by oligoubiquitination. Immunity 25: 885-894 (2006). *
van Oosterhout C. Trans-species polymorphism, HLA-disease associations and the evolution of the MHC. Commun. Integr. Biol. 2: 408-410 (2009). *
van Oosterhout C. A new theory of MHC evolution: beyond selection on the immune genes. Proc. Biol. Sci. 276: 657-665 (2009). *
Van Tol EA, Verspaget HW, Pena AS, Kraemer CV, Lamers CB. The CD56 adhesion molecule is the major determinant for detecting non-major histocompatibility complex-restricted cytotoxic mononuclear cells from the intestinal lamina propria. Eur. J. Immunol. 22: 23-29 (1992).
van Tol EA, Verspaget HW, Pena AS, Lamers CB. Normal inflammatory bowel disease mucosa conceals alterations in natural killer cell activity. Scand. J. Gastroenterol. 27: 999-1005 (1992).
Vandiedonck C, Knight JC. The human major histocompatibility complex as a paradigm in genomics research. Brief. Funct. Genomic. Proteomic. 8: 379-394 (2009).
Varga E, Petro A, Jager R, Varga L. Two faces of an illness: ankylosing spondylitis developed after rheumatoid arthritis. Orv. Hetil. 150: 2000-2003 (2009).
Vargas P, Cortes C, Vargas L, Rosemblatt M, Bono MR. Immunization with antigen-pulsed dendritic cells significantly improves the immune response to weak self-antigens. Immunobiology 211: 29-36 (2006).
Vargas-Alarcon G, Granados J, Martinez-Laso J, Gomez-Casado E, Zuniga J, Salgado N, Hernandez-Pacheco G, Hesiquio R, Rodriguez-Reyna TS, Gamboa R, Alcocer-Varela J, Arnaiz-Villena A. Lack of association between the polymorphism at the heat-shock protein (HSP70-2) gene and systemic lupus erythematosus (SLE) in the Mexican Mestizo population. Genes Immun. 1: 367-370 (2000). *
Vargas-Alarcon G, Salgado N, Granados J, Gomez-Casado E, Martinez-Laso J, Alcocer-Varela J, Arnaiz-Villena A, Alarcon-Segovia D. Class II allele and haplotype frequencies in Mexican systemic lupus erythematosus patients: the relevance of considering homologous chromosomes in determining susceptibility. Hum. Immunol. 62: 814-820 (2001).
Vargas-Alarcon G, Soto ME, Perez-Hernandez N, Cicero-Sabido R, Ramirez E, Alvarez-Leon E, Reyes PA. Comparative study of the residues 63 and 67 on the HLA-B molecule in patients with Takayasu's arteritis and tuberculosis. Cell. Biochem. Funct. 26: 820-823 (2008). *
Vartdal F. Genetic background for immune-mediated diseases. Acta Odontol. Scand. 59: 212-215 (2001).
Vasconcelos C, Carvalho C, Leal B, Pereira C, Bettencourt A, Costa PP, Marinho A, Barbosa P, Almeida I, Farinha F, Mendonca T, Correia JA, Mendonca D, Martins B. HLA in Portuguese systemic lupus erythematosus patients and their relation to clinical features. Ann. N. Y. Acad. Sci. 1173: 575-580 (2009). *
Vascotto F, Lankar D, Faure-Andre G, Vargas P, Diaz J, Le Roux D, Yuseff MI, Sibarita JB, Boes M, Raposo G, Mougneau E, Glaichenhaus N, Bonnerot C, Manoury B, Lennon-Dumenil AM. The actin-based motor protein myosin II regulates MHC class II trafficking and BCR-driven antigen presentation. J. Cell Biol. 176: 1007-1019 (2007). *
Vasey FB, Espinoza LR, Bocanegra TS, Germain BF. The major histocompatibility complex. Ann. Clin. Lab. Sci. 12: 16-22 (1982).
Vatay A, Rajczy K, Pozsonyi E, Hosszufalusi N, Prohaszka Z, Fust G, Karadi I, Szalai C, Grosz A, Bartfai Z, Panczel P. Differences in the genetic background of latent autoimmune diabetes in adults (LADA) and type 1 diabetes mellitus. Immunol. Lett. 84: 109-115 (2002).
Vazquez-Garcia MN, Alaez C, Olivo A, Debaz H, Perez-Luque E, Burguete A, Cano S, de la Rosa G, Bautista N, Hernandez A, Bandera J, Torres LF, Kershenobich D, Alvarez F, Gorodezky C. MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis. J. Hepatol. 28: 985-990 (1998). *
Veal CD, Capon F, Allen MH, Heath EK, Evans JC, Jones A, Patel S, Burden D, Tillman D, Barker JN, Trembath RC. Family-based analysis using a dense single-nucleotide polymorphism-based map defines genetic variation at PSORS1, the major psoriasis-susceptibility locus. Am. J. Hum. Genet. 71: 554-564 (2002). *
Vegvari A, Szabo Z, Szanto S, Glant TT, Mikecz K, Szekanecz Z. The genetic background of ankylosing spondylitis. Joint Bone Spine 76: 623-628 (2009). *
Veit T, Cordero E, Mucenic T, Monticielo O, Brenol J, Xavier R, Delgado-Canedo A, Chies J. Association of the HLA-G 14 bp polymorphism with systemic lupus erythematosus. Lupus 18: 424-430 (2009). *
Velardi A, Ruggeri L, Mancusi A, Burchielli E, Perruccio K, Aversa F, Martelli MF; on behalf of the Immunobiology Working Party of the European Group for Blood and Marrow Transplantation (EBMT). Clinical impact of natural killer cell reconstitution after allogeneic hematopoietic transplantation. Semin. Immunopathol. 30: 489-503 (2008). *
Velten F, Rogel-Gaillard C, Renard C, Pontarotti P, Tazi-Ahnini R, Vaiman M, Chardon P. A first map of the porcine major histocompatibility complex class I region. Tissue Antigens 51: 183-194 (1998).
Venkataraman GM, Suciu D, Groh V, Boss JM, Spies T. Promoter region architecture and transcriptional regulation of the genes for the MHC class I-related chain A and B ligands of NKG2D. J. Immunol. 178: 961-969 (2007). *
Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ. Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells. Nat. Chem. Biol. 3: 222-228 (2007). *
Venturi V, Chin HY, Asher TE, Ladell K, Scheinberg P, Bornstein E, van Bockel D, Kelleher AD, Douek DC, Price DA, Davenport MP. TCR beta-chain sharing in human CD8+ T cell responses to cytomegalovirus and EBV. J. Immunol. 181: 7853-7862 (2008). *
Venzke S, Michel N, Allespach I, Fackler OT, Keppler OT. Expression of Nef downregulates CXCR4, the major coreceptor of human immunodeficiency virus, from the surface of target cells and thereby enhances resistance to superinfection. J. Virol. 80: 11141-11152 (2006). *
Verity DH, Vaughan RW, Kondeatis E, Madanat W, Zureikat H, Fayyad F, Marr JE, Kanawati CA, Wallace GR, Stanford MR. Intercellular adhesion molecule-1 gene polymorphisms in Behcet's disease. Eur. J. Immunogenet. 27: 73-76 (2000).
Verity DH, Wallace GR, Vaughan RW, Kondeatis E, Madanat W, Zureikat H, Fayyad F, Marr JE, Kanawati CA, Stanford MR. HLA and tumour necrosis factor (TNF) polymorphisms in ocular Behcet's disease. Tissue Antigens 54: 264-272 (1999). *
Verma B, Neethling FA, Caseltine S, Fabrizio G, Largo S, Duty JA, Tabaczewski P, Weidanz JA. TCR mimic monoclonal antibody targets a specific peptide/HLA class I complex and significantly impedes tumor growth in vivo using breast cancer models. J. Immunol. Jan 11 [Epub ahead of print] (2010).
Verpoort KN, Cheung K, Ioan-Facsinay A, van der Helm-van Mil AH, de Vries-Bouwstra JK, Allaart CF, Drijfhout JW, de Vries RR, Breedveld FC, Huizinga TW, Pruijn GJ, Toes RE. Fine specificity of the anti-citrullinated protein antibody response is influenced by the shared epitope alleles. Arthritis Rheum. 56: 3949-3952 (2007). *
Vertuani S, De Geer A, Levitsky V, Kogner P, Kiessling R, Levitskaya J. Retinoids act as multistep modulators of the major histocompatibility class I presentation pathway and sensitize neuroblastomas to cytotoxic lymphocytes. Cancer Res. 63: 8006-8013 (2003). *
Viau S, Maire MA, Pasquis B, Gregoire S, Acar N, Bron AM, Bretillon L, Creuzot-Garcher CP, Joffre C. Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Graefes Arch. Clin. Exp. Ophthalmol. 247: 1039-1050 (2009). *
Vidal SM, Lanier LL. NK cell recognition of mouse cytomegalovirus-infected cells. Curr. Top. Microbiol. Immunol. 298: 183-206 (2006).
Vider-Shalit T, Sarid R, Maman K, Tsaban L, Levi R, Louzoun Y. Viruses selectively mutate their CD8+ T-cell epitopes - a large-scale immunomic analysis. Bioinformatics 25: i39-i44 (2009). *
Vieira J, Cardoso CS, Pinto J, Patil K, Brazdil P, Cruz E, Mascarenhas C, Lacerda R, Gartner A, Almeida S, Alves H, Porto G. A putative gene located at the MHC class I region around the D6S105 marker contributes to the setting of CD8+ T-lymphocyte numbers in humans. Int. J. Immunogenet. 34: 359-367 (2007). *
Viel DO, Tsuneto LT, Sossai CR, Lieber SR, Marques SB, Vigorito AC, Aranha FJ, de Brito Eid KA, Oliveira GB, Miranda EC, de Souza CA, Visentainer JE. IL2 and TNFA gene polymorphisms and the risk of graft-versus-host disease after allogeneic haematopoietic stem cell transplantation. Scand. J. Immunol. 66: 703-710 (2007). *
Vierling JM. The liver as an immune organ. Falk Symposium 135. Immmunological diseases of liver and gut. Prague (Czech Republic). p. 19-22. September 12 - 13 (2003). *
Vierling JM. Primary sclerosing cholangitis: is autoimmunity involved in pathogenesis? Falk Symposium 142. GASTROENTEROLOGY WEEK FREIBURG 2004 (Part I) AUTOIMMUNE LIVER DISEASE, Freiburg (Germany), pp. 43-44. October 12-13 (2004). *
Vierling JM. Is primary sclerosing cholangitis an autoimmune disease? Falk Symposium 136. XII FALK LIVER WEEK 2003 (Part I) In Honour of Hans Popper�s 100th Birthday. Cholestatic Liver Diseases: Therapeutical Options and Perspectives. Freiburg (Germany). p. 67-69. October 15-16 (2003). *
Vignal C, Bansal AT, Balding DJ, Binks MH, Dickson MC, Montgomery DS, Wilson AG. Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci. Arthritis Rheum. 60: 53-62 (2009). *
Vigneron N, Stroobant V, Chapiro J, Ooms A, Degiovanni G, Morel S, van der Bruggen P, Boon T, Van den Eynde BJ. An antigenic peptide produced by peptide splicing in the proteasome. Science 304: 587-590 (2004). *
Viken MK, Blomhoff A, Olsson M, Akselsen HE, Pociot F, Nerup J, Kockum I, Cambon-Thomsen A, Thorsby E, Undlien DE, Lie BA. Reproducible association with type 1 diabetes in the extended class I region of the major histocompatibility complex. Genes Immun. 10: 323-333 (2009). *
Vilches C, Parham P. KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu. Rev. Immunol. 20: 217-251 (2002). *
Villasenor J, Besse W, Benoist C, Mathis D. Ectopic expression of peripheral-tissue antigens in the thymic epithelium: probabilistic, monoallelic, misinitiated. Proc. Natl. Acad. Sci. U.S.A. 105: 15854-15859 (2008). *
Visvanathan K, Charles A, Bannan J, Pugach P, Kashfi K, Zabriskie JB. Inhibition of bacterial superantigens by peptides and antibodies. Infect. Immun. 69: 875-884 (2001). *
Vitalis TZ, Zhang QJ, Alimonti J, Chen SS, Basha G, Moise A, Tiong J, Tian MM, Choi KB, Waterfield D, Jeffries A, Jefferies WA. Using the TAP component of the antigen-processing machinery as a molecular adjuvant. PLoS Pathog. 1: e36 (2005). *
Vogel A, Manns MP, Strassburg CP. Autoimmunity and viruses. Clin. Liver Dis. 6: 451-465 (2002).
Volanakis JE, Zhu ZB, Schaffer FM, Macon KJ, Palermos J, Barger BO, Go R, Campbell RD, Schroeder HW Jr, Cooper MD. Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency. J. Clin. Invest. 89: 1914-1922 (1992). *
von Bergwelt-Baildon MS, Shimabukuro-Vornhagen A, Klein-Gonzalez N, Kondo E. T-cell responses to cyclin B1 are not restricted to p53-overexpressing tumors. Clin. Cancer Res. 15: 7106 (2009). *
von Boehmer H. Central tolerance: essential for preventing autoimmune disease? Eur. J. Immunol. 39: 2313-2316 (2009). *
von Delwig A, Altmann DM, Charlton FG, McKie N, Isaacs JD, Holmdahl R, Robinson JH. T cell responses to a non-glycosylated epitope predominate in type II collagen-immunized HLA-DRB1*0101 transgenic mice. Ann. Rheum. Dis. 66: 599-604 (2007). *
von Delwig A, Altmann DM, Isaacs JD, Harding CV, Holmdahl R, McKie N, Robinson JH. The impact of glycosylation on HLA-DR1-restricted T cell recognition of type II collagen in a mouse model. Arthritis Rheum. 54: 482-491 (2006). *
von Freeden-Jeffry U, Davidson N, Wiler R, Fort M, Burdach S, Murray R. IL-7 deficiency prevents development of a non-T cell non-B cell-mediated colitis. J. Immunol. 161: 5673-5680 (1998). *
von Oppen N, Schurich A, Hegenbarth S, Stabenow D, Tolba R, Weiskirchen R, Geerts A, Kolanus W, Knolle P, Diehl L. Systemic antigen cross-presented by liver sinusoidal endothelial cells induces liver-specific CD8 T-cell retention and tolerization. Hepatology 49: 1664-1672 (2009).
von Salome J, Kukkonen JP. Sequence features of HLA-DRB1 locus define putative basis for gene conversion and point mutations. BMC Genomics 9: 228 (2008). *
von Vietinghoff S, Busjahn A, Schonemann C, Massenkeil G, Otto B, Luft FC, Kettritz R. Major histocompatibility complex HLA region largely explains the genetic variance exercised on neutrophil membrane proteinase 3 expression. J. Am. Soc. Nephrol. 17: 3185-3191 (2006). *
Voo KS, Fu T, Wang HY, Tellam J, Heslop HE, Brenner MK, Rooney CM, Wang RF. Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes. J. Exp. Med. 199: 459-470 (2004). *
Vorechovsky I, Cullen M, Carrington M, Hammarstrom L, Webster AD. Fine mapping of IGAD1 in IgA deficiency and common variable immunodeficiency: identification and characterization of haplotypes shared by affected members of 101 multiple-case families. J. Immunol. 164: 4408-4416 (2000). *
Vorechovsky I, Kralovicova J, Laycock MD, Webster AD, Marsh SG, Madrigal A, Hammarstrom L. Short tandem repeat (STR) haplotypes in HLA: an integrated 50-kb STR/linkage disequilibrium/gene map between the RING3 and HLA-B genes and identification of STR haplotype diversification in the class III region. Eur. J. Hum. Genet. 9: 590-598 (2001). *
Vorechovsky I, Webster AD, Plebani A, Hammarstrom L. Genetic linkage of IgA deficiency to the major histocompatibility complex: evidence for allele segregation distortion, parent-of-origin penetrance differences, and the role of anti-IgA antibodies in disease predisposition. Am. J. Hum. Genet. 64: 1096-1109 (1999). *
Vorechovsky I, Zetterquist H, Paganelli R, Koskinen S, Webster AD, Bjorkander J, Smith CI, Hammarstrom L. Family and linkage study of selective IgA deficiency and common variable immunodeficiency. Clin. Immunol. Immunopathol. 77: 185-192 (1995). *
Vos Q, Lees A, Wu ZQ, Snapper CM, Mond JJ. B-cell activation by T-cell-independent type 2 antigens as an integral part of the humoral immune response to pathogenic microorganisms. Immunol. Rev. 176: 154-170 (2000). *
Vyse TJ, Kotzin BL. Genetic susceptibility to systemic lupus erythematosus. Annu. Rev. Immunol. 16: 261-292 (1998). *
Waeckerle-Men Y, Starke A, Wuthrich RP. PD-L1 partially protects renal tubular epithelial cells from the attack of CD8+cytotoxic T cells. Nephrol. Dial. Transplant. 22: 1527-1536 (2007).
Wagner H. The immunogenicity of CpG-antigen conjugates. Adv. Drug Deliv. Rev. 61: 243-247 (2009).
Wahl A, Schafer F, Bardet W, Buchli R, Air GM, Hildebrand WH. HLA class I molecules consistently present internal influenza epitopes. Proc. Natl. Acad. Sci. U.S.A. 106: 540-545 (2009). *
Wakasa-Morimoto C, Toyosaki-Maeda T, Matsutani T, Yoshida R, Nakamura-Kikuoka S, Maeda-Tanimura M, Yoshitomi H, Hirota K, Hashimoto M, Masaki H, Fujii Y, Sakata T, Tsuruta Y, Suzuki R, Sakaguchi N, Sakaguchi S. Arthritis and pneumonitis produced by the same T cell clones from mice with spontaneous autoimmune arthritis. Int. Immunol. 20: 1331-1342 (2008).
Waldrep ML, Zhuang Y, Schroeder HW Jr. Analysis of TACI mutations in CVID & RESPI patients who have inherited HLA B*44 or HLA*B8. BMC Med. Genet. 10: 100 (2009). *
Walker DJ, Griffiths M, Dewar P, Coates E, Dick WC, Thompson M, Griffiths ID. Association of MHC antigens with susceptibility to and severity of rheumatoid arthritis in multicase families. Ann. Rheum. Dis. 44: 519-525 (1985). *
Walker NJ, Zurier RB. Liver abnormalities in rheumatic diseases. Clin. Liver Dis. 6: 933-946 (2002).
Wallace GR, Verity DH, Delamaine LJ, Ohno S, Inoko H, Ota M, Mizuki N, Yabuki K, Kondiatis E, Stephens HA, Madanat W, Kanawati CA, Stanford MR, Vaughan RW. MIC-A allele profiles and HLA class I associations in Behcet's disease. Immunogenetics 49: 613-617 (1999). *
Wallace HJ, Vandongen YK, Stacey MC. Tumor necrosis factor-alpha -308 gene polymorphism and venous leg ulceration - comment on possible link with obesity. J. Invest. Dermatol. 127: 1770-1771 (2007). *
Wallis RH, Wang K, Dabrowski D, Marandi L, Ning T, Hsieh E, Paterson AD, Mordes JP, Blankenhorn EP, Poussier P. A novel susceptibility locus on rat chromosome 8 affects spontaneous but not experimentally induced type 1 diabetes. Diabetes 56: 1731-1736 (2007). *
Walsh EC, Mather KA, Schaffner SF, Farwell L, Daly MJ, Patterson N, Cullen M, Carrington M, Bugawan TL, Erlich H, Campbell J, Barrett J, Miller K, Thomson G, Lander ES, Rioux JD. An integrated haplotype map of the human major histocompatibility complex. Am. J. Hum. Genet. 73: 580-590 (2003). *
Walsh KP, Brady MT, Finlay CM, Boon L, Kingston HG. Infection with a helminth parasite attenuates autoimmunity through TGF-beta-mediated suppression of Th17 and Th1 responses. J. Immunol. 183: 1577-1586 (2009).
Walsh MD, Dent OF, Young JP, Wright CM, Barker MA, Leggett BA, Bokey L, Chapuis PH, Jass JR, Macdonald GA. HLA-DR expression is associated with better prognosis in sporadic Australian clinicopathological stage C colorectal cancers. Int. J. Cancer 125: 1231-1237 (2009). *
Walshe VA, Hattotuwagama CK, Doytchinova IA, Wong M, Macdonald IK, Mulder A, Claas FH, Pellegrino P, Turner J, Williams I, Turnbull EL, Borrow P, Flower DR. Integrating in silico and in vitro analysis of peptide binding affinity to HLA-Cw*0102: a bioinformatic approach to the prediction of new epitopes. PLoS One 4: e8095 (2009). *
Walter L, Fischer K, Gunther E. Physical mapping of the Ring1, Ring2, Ke6, Ke4, Rxrb, Col11a2, and RT1.Hb genes in the rat major histocompatibility complex. Immunogenetics 44: 218-221 (1996).
Waly NE, Stokes CR, Gruffydd-Jones TJ, Day MJ. Immune cell populations in the duodenal mucosa of cats with inflammatory bowel disease. J. Vet. Intern. Med. 18: 816-825 (2004).
Wambre E, Van Overtvelt L, Maillere B, Humphreys R, von Hofe E, Ferhat L, Ebo D, Moingeon P. Single cell assessment of allergen-specific T cell responses with MHC class II peptide tetramers: methodological aspects. Int. Arch. Allergy Immunol. 146: 99-112 (2008).
Wan S, Xia C, Morel L. IL-6 produced by dendritic cells from lupus-prone mice inhibits CD4+CD25+ T cell regulatory functions. J. Immunol. 178: 271-279 (2007). *
Wanahita A, Davis B, Hamill RJ, Goldsmith EA, Rodgers JR, Cook RG, Lamphear JG, Musher DM. Clostridium difficile lacks detectable superantigen activity. FEMS Immunol. Med. Microbiol. 47: 275-277 (2006). *
Wandstrat A, Wakeland E. The genetics of complex autoimmune diseases: non-MHC susceptibility genes. Nat. Immunol. 2: 802-809 (2001). *
Wang B, Primeau TM, Myers N, Rohrs HW, Gross ML, Lybarger L, Hansen TH, Connolly JM. A single peptide-MHC complex positively selects a diverse and specific CD8 T cell repertoire. Science 326: 871-874 (2009). *
Wang BZ, Quan FS, Kang SM, Bozja J, Skountzou I, Compans RW. Incorporation of membrane-anchored flagellin into influenza virus-like particles enhances the breadth of immune responses. J. Virol. 82: 11813-11823 (2008). *
Wang C, Sanders CM, Yang Q, Schroeder HW Jr, Wang E, Babrzadeh F, Gharizadeh B, Myers RM, Hudson JR Jr, Davis RW, Han J. High throughput sequencing reveals a complex pattern of dynamic interrelationships among human T cell subsets. Proc. Natl. Acad. Sci. U.S.A. 107: 1518-1523 (2010). *
Wang F, Liu H, Blanton WP, Belkina A, Lebrasseur NK, Denis GV. Brd2 disruption in mice causes severe obesity without type 2 diabetes. Biochem. J. 425: 71-83 (2010). *
Wang H, Hao Q, Li QR, Yan XW, Ye S, Li YS, Li N, Li JS. Omega-3 polyunsaturated fatty acids affect lipopolysaccharide-induced maturation of dendritic cells through mitogen-activated protein kinases p38. Nutrition 23: 474-482 (2007).
Wang J, Roderiquez G, Jones T, McPhie P, Norcross MA. Control of in vitro immune responses by regulatory oligodeoxynucleotides through inhibition of pIII promoter directed expression of MHC class II transactivator in human primary monocytes. J. Immunol. 179: 45-52 (2007). *
Wang K, Baldassano R, Zhang H, Qu HQ, Imielinski M, Kugathasan S, Annese V, Dubinsky M, Rotter JI, Russell RK, Bradfield JP, Sleiman PM, Glessner JT, Walters T, Hou C, Kim C, Frackelton EC, Garris M, Doran J, Romano C, Catassi C, Van Limbergen J, et al. Comparative genetic analysis of inflammatory bowel disease and type 1 diabetes implicates multiple loci with opposite effects. Hum. Mol. Genet. Feb 22 [Epub ahead of print] (2010).
Wang L, Bosselut R. CD4-CD8 lineage differentiation: Thpok-ing into the nucleus. J. Immunol. 183: 2903-2910 (2009).
Wang L, Wildt KF, Zhu J, Zhang X, Feigenbaum L, Tessarollo L, Paul WE, Fowlkes BJ, Bosselut R. Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat. Immunol. 9: 1122-1130 (2008). *
Wang L, Xiang Z, Ma LL, Chen Z, Gao X, Sun Z, Williams P, Chari RS, Yin DP. Deficiency of protein kinase C-theta facilitates tolerance induction. Transplantation 87: 507-516 (2009).
Wang M, Bai F, Pries M, Buus S, Prause JU, Nissen MH. Identification of MHC class I H-2 Kb/Db-restricted immunogenic peptides derived from retinal proteins. Invest. Ophthalmol. Vis. Sci. 47: 3939-3945 (2006). *
Wang M, Harhaji L, Lamberth K, Harndahl M, Buus S, Heegaard NH, Claesson MH, Nissen MH. Modified human beta 2-microglobulin (desLys(58)) displays decreased affinity for the heavy chain of MHC class I and induces nitric oxide production and apoptosis. Scand. J. Immunol. 69: 203-212 (2009). *
Wang MG, Szebeni J, Pearson DA, Szot GL, Sykes M. Inhibition of graft-versus-host disease by interleukin-2 treatment is associated with altered cytokine production by expanded graft-versus-host-reactive CD4+ helper cells. Transplantation 60: 481-490 (1995).
Wang N, Campo M, Ting L, Fleming C, Terhorst C, Finn PW. The costimulatory molecule SLAM is critical for pulmonary allergic responses. Am. J. Respir. Cell. Mol. Biol. 35: 206-210 (2006). *
Wang Q, Liu C, Zhu F, Liu F, Zhang P, Guo C, Wang X, Li H, Ma C, Sun W, Zhang Y, Chen W, Zhang L. Reoxygenation of hypoxia-differentiated dentritic cells induces Th1 and Th17 cell differentiation. Mol. Immunol. Nov 10 [Epub ahead of print] (2009). *
Wang Q, Sun B, Wang D, Ji Y, Kong Q, Wang G, Wang J, Zhao W, Jin L, Li H. Murine bone marrow mesenchymal stem cells cause mature dendritic cells to promote T-cell tolerance. Scand. J. Immunol. 68: 607-615 (2008). *
Wang QQ, Yang HZ, Hu ZW. Advances in the study of molecular mechanisms, applications and screening for altered peptide ligand. Yao Xue Xue Bao 43: 113-117 (2008).
Wang R, Natarajan K, Margulies DH. Structural basis of the CD8alphabeta/MHC class I interaction: focused recognition orients CD8beta to a T cell proximal position. J. Immunol. 183: 2554-2564 (2009).
Wang RF. Molecular cloning and characterization of MHC class I- and II-restricted tumor antigens recognized by T cells. Curr. Protoc. Immunol. Chapter 20: Unit 20.10 (2009).
Wang X, Chang X, Facchinetti V, Zhuang Y, Su B. MEKK3 is essential for lymphopenia-induced T cell proliferation and survival. J. Immunol. 182: 3597-3608 (2009).
Wang X, Herr RA, Chua WJ, Lybarger L, Wiertz EJ, Hansen TH. Ubiquitination of serine, threonine, or lysine residues on the cytoplasmic tail can induce ERAD of MHC-I by viral E3 ligase mK3. J. Cell Biol. 177: 613-624 (2007). *
Wang X, Hisha H, Cui W, Song C, Mizokami T, Okazaki S, Li Q, Feng W, Kato J, Jiang S, Fan H, Ikehara S. The characteristics of hematopoietic stem cells from autoimmune-prone mice and the role of neural cell adhesion molecules in abnormal proliferation of these cells in MRL/lpr mice. Haematologica 92: 300-307 (2007). *
Wang X, Simone LC, Tuli A, Solheim JC. Comparative analysis of the impact of a free cysteine in tapasin on the maturation and surface expression of murine MHC class I allotypes. Int. J. Immunogenet. 36: 183-187 (2009). *
Wang XC, Zhang JQ, Shen YQ, Miao FQ, Xie W. Loss of heterozygosity at 6p21.3 underlying HLA class I downregulation in gastric cancer. J. Exp. Clin. Cancer Res. 25: 115-119 (2006).
Wang Y, Kissenpfennig A, Mingueneau M, Richelme S, Perrin P, Chevrier S, Genton C, Lucas B, Disanto JP, Acha-Orbea H, Malissen B, Malissen M. Th2 l