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Scientific Literature, MDR or MRP
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Abd El-Ghaffar HA, Aladle DA, Farahat SE, Abd El-Hady N. P-Glycoprotein (P-170) expression in acute leukemias.
Hematology 11: 35-41 (2006).
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Abdullaev IF, Rudkouskaya A, Schools GP, Kimelberg HK, Mongin AA. Pharmacological comparison of swelling-activated excitatory amino acid release and Cl- currents in rat cultured astrocytes.
J. Physiol. 572: 677-689 (2006).
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Abulrob AG, Gumbleton M. Transport of phosphatidylcholine in MDR3-negative epithelial cell lines via drug-induced MDR1 P-glycoprotein.
Biochem. Biophys. Res. Commun. 262: 121-126 (1999).
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Acalovschi M, Tirziu S, Chiorean E, Krawczyk M, Grunhage F, Lammert F. Common variants of ABCB4 and ABCB11 and plasma lipid levels: a study in sib pairs with gallstones, and controls.
Lipids 44: 521-526 (2009).
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Accatino L, Pizarro M, Solis N, Koenig CS, Vollrath V, Chianale J. Modulation of hepatic content and biliary excretion of P-glycoproteins in hepatocellular and obstructive cholestasis in the rat.
J. Hepatol. 25: 349-361 (1996).
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Achard-Joris M, Bourdineaud JP. Heterologous expression of bacterial and human multidrug resistance proteins protect Escherichia coli against mercury and zinc contamination.
Biometals 19: 695-704 (2006).
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Adachi M, Reid G, Schuetz JD. Therapeutic and biological importance of getting nucleotides out of cells: a case for the ABC transporters, MRP4 and 5.
Adv. Drug Deliv. Rev. 54: 1333-1342 (2002).
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Adachi T, Nakagawa H, Hagiya Y, Yasuoka T, Ishikawa T. Transport-metabolism interplay: LXR-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
Mol. Pharm. 6: 1678-1688 (2009).
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Adachi Y, Kamisako T. Intrahepatic cholestasis.
Nippon Rinsho 54: 788-793 (1996).
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Adachi Y, Kamisako T, Okuyama Y, Miya H. Hepatic metabolism and transport of bilirubin and other organic anions.
Nippon Rinsho 54: 2276-2290 (1996).
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Agarwal R, Agarwal C, Ichikawa H, Singh RP, Aggarwal BB. Anticancer potential of silymarin: from bench to bed side.
Anticancer Res. 26: 4457-4498 (2006).
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Agostinelli E, Tempera G, Molinari A, Salvi M, Battaglia V, Toninello A, Arancia G. The physiological role of biogenic amines redox reactions in mitochondria. New perspectives in cancer therapy.
Amino Acids 33: 175-187 (2007).
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Ahmed FE. Molecular markers that predict response to colon cancer therapy.
Expert Rev. Mol. Diagn. 5: 353-375 (2005).
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Ahmed S, Vo NT, Thalhammer T, Thalhammer F, Gattringer KB, Jager W. Involvement of Mrp2 (Abcc2) in biliary excretion of moxifloxacin and its metabolites in the isolated perfused rat liver.
J. Pharm. Pharmacol. 60: 55-62 (2008).
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Aird RE, Thomson M, Macpherson JS, Thurston DE, Jodrell DI, Guichard SM. ABCB1 genetic polymorphism influences the pharmacology of the new pyrrolobenzodiazepine derivative SJG-136.
Pharmacogenomics J. 8: 289-296 (2008).
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Aisen AM, Sherman S, Jennings SG, Fogel EL, Li T, Cheng CL, Devereaux BM, McHenry L, Watkins JL, Lehman GA. Comparison of secretin-stimulated magnetic resonance pancreatography and manometry results in patients with suspected sphincter of oddi dysfunction.
Acad. Radiol. 15: 601-609 (2008).
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Ak Y, Demirel G, Gulbas Z. MDR1, MRP1 and LRP expression in patients with untreated acute leukaemia: correlation with 99mTc-MIBI bone marrow scintigraphy.
Nucl. Med. Commun. 28: 541-546 (2007).
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Akashi M, Tanaka A, Takikawa H. Effect of cyclosporin A on the biliary excretion of cholephilic compounds in rats.
Hepatol. Res. 34: 193-198 (2006).
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Akbas SH, Bilgen T, Keser I, Tuncer M, Yucetin L, Tosun O, Gultekin M, Luleci G. The effect of MDR1 (ABCB1) polymorphism on the pharmacokinetic of tacrolimus in Turkish renal transplant recipients.
Transplant. Proc. 38: 1290-1292 (2006).
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Akita H, Suzuki H, Ito K, Kinoshita S, Sato N, Takikawa H, Sugiyama Y. Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump.
Biochim. Biophys. Acta 1511: 7-16 (2001).
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Akita H, Suzuki H, Sugiyama Y. Sinusoidal efflux of taurocholate correlates with the hepatic expression level of Mrp3.
Biochem. Biophys. Res. Commun. 299: 681-687 (2002).
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Akoume MY, Tuchweber B, Plaa GL, Yousef IM. The role of mdr2 in manganese-bilirubin induced cholestasis in mice.
Toxicol. Lett. 148: 41-51 (2004).
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Albermann N, Schmitz-Winnenthal FH, Z'graggen K, Volk C, Hoffmann MM, Haefeli WE, Weiss J. Expression of the drug transporters MDR1/ABCB1, MRP1/ABCC1, MRP2/ABCC2, BCRP/ABCG2, and PXR in peripheral blood mononuclear cells and their relationship with the expression in intestine and liver.
Biochem. Pharmacol. 70: 949-958 (2005).
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Albrecht C, Elliott JI, Sardini A, Litman T, Stieger B, Meier PJ, Higgins CF. Functional analysis of candidate ABC transporter proteins for sitosterol transport.
Biochim. Biophys. Acta 1567: 133-142 (2002).
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Aleksunes LM, Yeager RL, Klaassen CD. Application of multivariate statistical procedures to identify transcription factors that correlate with MRP2, 3, and 4 mRNA in adult human livers.
Xenobiotica 39: 514-522 (2009).
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Alhanout K, Brunel JM, Raoult D, Rolain JM. In vitro antibacterial activity of aminosterols against multidrug-resistant bacteria from patients with cystic fibrosis.
J. Antimicrob. Chemother. 64: 810-814 (2009).
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Allen JD, Van Dort SC, Buitelaar M, van Tellingen O, Schinkel AH. Mouse breast cancer resistance protein (Bcrp1/Abcg2) mediates etoposide resistance and transport, but etoposide oral availability is limited primarily by P-glycoprotein.
Cancer Res. 63: 1339-1344 (2003).
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Aller SG, Yu J, Ward A, Weng Y, Chittaboina S, Zhuo R, Harrell PM, Trinh YT, Zhang Q, Urbatsch IL, Chang G. Structure of P-glycoprotein reveals a molecular basis for poly-specific drug binding.
Science 323: 1718-1722 (2009).
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Alrefai WA, Gill RK. Bile acid transporters: structure, function, regulation and pathophysiological implications.
Pharm. Res. 24: 1803-1823 (2007).
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Alves-Filho JC, Tavares-Murta BM, Barja-Fidalgo C, Benjamim CF, Basile-Filho A, Arraes SM, Cunha FQ. Neutrophil function in severe sepsis.
Endocr. Metab. Immune Disord. Drug Targets 6: 151-158 (2006).
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Anapolsky A, Teng S, Dixit S, Piquette-Miller M. The role of pregnane X receptor in 2-acetylaminofluorene-mediated induction of drug transport and metabolizing enzymes in mice.
Drug Metab. Dispos. 34: 405-409 (2006).
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Andersen V, Agerstjerne L, Jensen D, Ostergaard M, Saebo M, Hamfjord J, Kure E, Vogel U. The multidrug resistance 1 (MDR1) gene polymorphism G-rs3789243-A is not associated with disease susceptibility in Norwegian patients with colorectal adenoma and colorectal cancer; a case control study.
BMC Med. Genet. 10: 18 (2009).
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Andersen V, Ostergaard M, Christensen J, Overvad K, Tjonneland A, Vogel U. Polymorphisms in the xenobiotic transporter multidrug resistance 1 (MDR1) gene and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study.
BMC Cancer 9: 407 (2009).
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Anderson CA, Massey DC, Barrett JC, Prescott NJ, Tremelling M, Fisher SA, Gwilliam R, Jacob J, Nimmo ER, Drummond H, Lees CW, Onnie CM, Hanson C, Blaszczyk K, Ravindrarajah R, Hunt S, Varma D, Hammond N, Lewis G, Attlesey H, Watkins N, et al. Investigation of Crohn’s disease risk loci in ulcerative colitis further defines their molecular relationship.
Gastroenterology 136: 523-529.e3 (2009).
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Andrejko KM, Raj NR, Kim PK, Cereda M, Deutschman CS. IL-6 modulates sepsis-induced decreases in transcription of hepatic organic anion and bile acid transporters.
Shock 29: 490-496 (2008).
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Anglicheau D, Legendre C, Thervet E. Pharmacogenetics in solid organ transplantation: present knowledge and future perspectives.
Transplantation 78: 311-315 (2004).
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Anglicheau D, Thervet E, Etienne I, Hurault De Ligny B, Le Meur Y, Touchard G, Buchler M, Laurent-Puig P, Tregouet D, Beaune P, Daly A, Legendre C, Marquet P. CYP3A5 and MDR1 genetic polymorphisms and cyclosporine pharmacokinetics after renal transplantation.
Clin. Pharmacol. Ther. 75: 422-433 (2004).
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Annereau JP, Szakacs G, Tucker CJ, Arciello A, Cardarelli C, Collins J, Grissom S, Zeeberg B, Reinhold W, Weinstein J, Pommier Y, Paules RS, Gottesman MM. Analysis of ATP-binding cassette transporter expression in drug-selected cell lines by a microarray dedicated to multidrug resistance.
Mol. Pharmacol. 66: 1397-1405 (2004).
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Annese V, Latiano A, Rossi L, Bossa F, Damonte G, Dallapiccola B, Serafini S, Pierige F, Andriulli A, Magnani M. The polymorphism of multi-drug resistance 1 gene (MDR1) does not influence the pharmacokinetics of dexamethasone loaded into autologous erythrocytes of patients with inflammatory bowel disease.
Eur. Rev. Med. Pharmacol. Sci. 10: 27-31 (2006).
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Annese V, Valvano MR, Palmieri O, Latiano A, Bossa F, Andriulli A. Multidrug resistance 1 gene in inflammatory bowel disease: a meta-analysis.
World J. Gastroenterol. 12: 3636-3644 (2006).
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Ano H, Matsumoto T, Suetake T, Nagai T, Tamura Y, Takamatsu I, Iwasaki T, Matsuoka H, Sasada S, Tetsumoto S, Tsuyuguchi I, Kusunoki Y, Takashima T. Relationship between the isoniazid-resistant mutation katGS315T and the prevalence of MDR-/XDR-TB in Osaka, Japan.
Int. J. Tuberc. Lung Dis. 12: 1300-1305 (2008).
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Ansari SR, Hanna H, Hachem R, Jiang Y, Rolston K, Raad I. Risk factors for infections with multidrug-resistant Stenotrophomonas maltophilia in patients with cancer.
Cancer 109: 2615-2622 (2007).
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Anthoni H, Zucchelli M, Matsson H, Muller-Myhsok B, Fransson I, Schumacher J, Massinen S, Onkamo P, Warnke A, Griesemann H, Hoffmann P, Nopola-Hemmi J, Lyytinen H, Schulte-Korne G, Kere J, Nothen MM, Peyrard-Janvid M. A locus on 2p12 containing the co-regulated MRPL19 and C2ORF3 genes is associated to dyslexia.
Hum. Mol. Genet. 16: 667-677 (2007).
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Anuchapreeda S, Thanarattanakorn P, Sittipreechacharn S, Tima S, Chanarat P, Limtrakul P. Inhibitory effect of curcumin on MDR1 gene expression in patient leukemic cells.
Arch. Pharm. Res. 29: 866-873 (2006).
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Aoki K, Nakajima M, Hoshi Y, Saso N, Kato S, Sugiyama Y, Sato H. Effect of aminoguanidine on lipopolysaccharide-induced changes in rat liver transporters and transcription factors.
Biol. Pharm. Bull. 31: 412-420 (2008).
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Aoki K, Saso N, Kato S, Sugiyama Y, Sato H. Nitric oxide and peroxynitrite regulate transporter transcription in rat liver slices.
Biol. Pharm. Bull. 31: 1882-1887 (2008).
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Arab JP, Ramirez C, Munoz P, Pizarro M, Solís N, Riquelme A, Arrese M. Effects of Japanese herbal medicine inchin-ko-to on endotoxin-induced cholestasis in the rat.
Ann. Hepatol. 8: 228-233 (2009).
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Aranyi T, Ratajewski M, Bardoczy V, Pulaski L, Bors A, Tordai A, Varadi A. Identification of a DNA methylation-dependent activator sequence in the pseudoxanthoma elasticum gene, ABCC6.
J. Biol. Chem. 280: 18643-18550 (2005).
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Arcus VL, Lott JS, Johnston JM, Baker EN. The potential impact of structural genomics on tuberculosis drug discovery.
Drug Discov. Today 11: 28-34 (2006).
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Ardizzone S, Maconi G, Bianchi V, Russo A, Colombo E, Cassinotti A, Penati C, Tenchini ML, Bianchi Porro G. Multidrug resistance 1 gene polymorphism and susceptibility to inflammatory bowel disease.
Inflamm. Bowel Dis. 13: 516-523 (2007).
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Arnedo M, Taffe P, Sahli R, Furrer H, Hirschel B, Elzi L, Weber R, Vernazza P, Bernasconi E, Darioli R, Bergmann S, Beckmann JS, Telenti A, Tarr PE; the Swiss HIV Cohort Study. Contribution of 20 single nucleotide polymorphisms of 13 genes to dyslipidemia associated with antiretroviral therapy.
Pharmacogenet. Genomics 17: 755-764 (2007).
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Arnett HA, Escobar SS, Gonzalez-Suarez E, Budelsky AL, Steffen LA, Boiani N, Zhang M, Siu G, Brewer AW, Viney JL. BTNL2, a butyrophilin/B7-like molecule, is a negative costimulatory molecule modulated in intestinal inflammation.
J. Immunol. 178: 1523-1533 (2007).
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Arrese M. Cholestasis during pregnancy: rare hepatic diseases unmasked by pregnancy.
Ann. Hepatol. 5: 216-218 (2006).
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Arrese M, Accatino L. Is intrahepatic cholestasis of pregnancy an MDR3-related disease?
Gastroenterology 125: 1922-1923 (2003).
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Asamoto Y, Tazuma S, Ochi H, Chayama K, Suzuki H. Bile-salt hydrophobicity is a key factor regulating rat liver plasma-membrane communication: relation to bilayer structure, fluidity and transporter expression and function.
Biochem. J. 359: 605-610 (2001).
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Asghar A, Gorski JC, Haehner-Daniels B, Hall SD. Induction of multidrug resistance-1 and cytochrome P450 mRNAs in human mononuclear cells by rifampin.
Drug Metab. Dispos. 30: 20-26 (2002).
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Assaraf YG. The role of multidrug resistance efflux transporters in antifolate resistance and folate homeostasis.
Drug Resist. Updat. 9: 227-246 (2006).
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Assaraf YG, Rothem L, Hooijberg JH, Stark M, Ifergan I, Kathmann I, Dijkmans BA, Peters GJ, Jansen G. Loss of multidrug resistance protein 1 expression and folate efflux activity results in a highly concentrative folate transport in human leukemia cells.
J. Biol. Chem. 278: 6680-6686 (2003).
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Assem M, Schuetz EG, Leggas M, Sun D, Yasuda K, Reid G, Zelcer N, Adachi M, Strom S, Evans RM, Moore DD, Borst P, Schuetz JD. Interactions between hepatic Mrp4 and Sult2A as revealed by the constitutive androstane receptor and Mrp4 knockout mice.
J. Biol. Chem. 279: 22250-22257 (2004).
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Assenat E, Gerbal-Chaloin S, Larrey D, Saric J, Fabre JM, Maurel P, Vilarem MJ, Pascussi JM. Interleukin 1beta inhibits CAR-induced expression of hepatic genes involved in drug and bilirubin clearance.
Hepatology 40: 951-960 (2004).
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Atalay C, Deliloglu Gurhan I, Irkkan C, Gunduz U. Multidrug resistance in locally advanced breast cancer.
Tumour Biol. 27: 309-318 (2006).
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Augustine LM, Markelewicz RJ Jr, Boekelheide K, Cherrington NJ. Xenobiotic and endobiotic transporter mRNA expression in the blood-testis barrier.
Drug Metab. Dispos. 33: 182-189 (2005).
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Autschbach F, Giese T, Gassler N, Sido B, Heuschen G, Heuschen U, Zuna I, Schulz P, Weckauf H, Berger I, Otto HF, Meuer SC. Cytokine/chemokine messenger-RNA expression profiles in ulcerative colitis and Crohn's disease.
Virchows Arch. 441: 500-513 (2002).
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Awasthi S, Sharma R, Singhal SS, Zimniak P, Awasthi YC. RLIP76, a novel transporter catalyzing ATP-dependent efflux of xenobiotics.
Drug Metab. Dispos. 30: 1300-1310 (2002).
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Ayrton A, Morgan P. Role of transport proteins in drug absorption, distribution and excretion.
Xenobiotica 31: 469-497 (2001).
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Azarpira N, Aghdaie MH, Behzad-Behbahanie A, Geramizadeh B, Behzadi S, Malekhoseinie SA, Raisjalal GH, Rahsaz M, Pourgholami A, Sagheb F. Association between cyclosporine concentration and genetic polymorphisms of CYP3A5 and MDR1 during the early stage after renal transplantation.
Exp. Clin. Transplant. 4: 416-419 (2006).
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Azzaroli F, Mennone A, Feletti V, Simoni P, Baglivo E, Montagnani M, Rizzo N, Pelusi G, DE Aloysio D, Lodato F, Festi D, Colecchia A, Roda E, Boyer JL, Mazzella G. Clinical trial: modulation of human placental multidrug resistance proteins in cholestasis of pregnancy by ursodeoxycholic acid.
Aliment. Pharmacol. Ther. 26: 1139-1146 (2007).
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Baars C, Leeb T, von Klopmann T, Tipold A, Potschka H. Allele-specific polymerase chain reaction diagnostic test for the functional MDR1 polymorphism in dogs.
Vet. J. 177: 394-397 (2008).
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Bacchetta J, Ranchin B, Brunet AS, Bouvier R, Duquesne A, Edery P, Fabien N, Peretti N. Autoimmune hypoparathyroidism in a 12-year-old girl with McKusick cartilage hair hypoplasia.
Pediatr. Nephrol. 24: 2449-2453 (2009).
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Bae SY, Choi SK, Kim KR, Park CS, Lee SK, Roh HK, Shin DW, Pie JE, Woo ZH, Kang JH. Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans.
Cancer Sci. 97: 774-779 (2006).
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Baghdasaryan A, Fickert P, Fuchsbichler A, Silbert D, Gumhold J, Horl G, Langner C, Moustafa T, Halilbasic E, Claudel T, Trauner M. Role of hepatic phospholipids in development of liver injury in Mdr2 (Abcb4) knockout mice.
Liver Int. 28: 948-958 (2008).
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Bai S, Stepkowski SM, Kahan BD, Brunner LJ. Metabolic interaction between cyclosporine and sirolimus.
Transplantation 77: 1507-1512 (2004).
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Baier PK, Hempel S, Waldvogel B, Baumgartner U. Zonation of hepatic bile salt transporters.
Dig. Dis. Sci. 51: 587-593 (2006).
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Bain LJ, Feldman RA. Altered expression of sulfotransferases, glucuronosyltransferases and mrp transporters in FVB/mrp1-/- mice.
Xenobiotica 33: 1173-1183 (2005).
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Bakos E, Homolya L. Portrait of multifaceted transporter, the multidrug resistance-associated protein 1 (MRP1/ABCC1).
Pflugers Arch. 453: 621-641 (2007).
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Balistreri WF. Genetic liver disease.
54th Annual Meeting of the American Association for the Study of Liver Diseases (2003).
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Balkova K, Gbelska Y. ABC transporter proteins in multidrug resistance of microorganisms.
Epidemiol. Mikrobiol. Imunol. 56: 129-139 (2007).
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Ballatori N, Fang F, Christian WV, Li N, Hammond CL. Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver.
Am. J. Physiol. Gastrointest. Liver Physiol. 295: G179-G186 (2008).
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Ballatori N, Hammond CL, Cunningham JB, Krance SM, Marchan R. Molecular mechanisms of reduced glutathione transport: role of the MRP/CFTR/ABCC and OATP/SLC21A families of membrane proteins.
Toxicol. Appl. Pharmacol. 204: 238-255 (2005).
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Ballatori N, Henson JH, Seward DJ, Cai SY, Runnegar M, Fricker G, Miller DS, Boyer JL. Retention of structural and functional polarity in cultured skate hepatocytes undergoing in vitro morphogenesis.
Comp. Biochem. Physiol. B. Biochem. Mol. Biol. 144: 167-179 (2006).
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Ballatori N, Rebbeor JF. Roles of MRP2 and oatp1 in hepatocellular export of reduced glutathione.
Semin. Liver Dis. 18: 377-387 (1998).
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Ballestero MR, Monte MJ, Briz O, Jimenez F, Gonzalez-San Martin F, Marin JJ. Expression of transporters potentially involved in the targeting of cytostatic bile acid derivatives to colon cancer and polyps.
Biochem. Pharmacol. 72: 729-738 (2006).
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Ban D, Kudo A, Sui S, Tanaka S, Nakamura N, Ito K, Suematsu M, Arii S. Decreased Mrp2-dependent bile flow in the post-warm ischemic rat liver.
J. Surg. Res. 153: 310-316 (2009).
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Banner KH, Cattaneo C, Net JL, Popovic A, Collins D, Gale JD. Macroscopic, microscopic and biochemical characterisation of spontaneous colitis in a transgenic mouse, deficient in the multiple drug resistance 1a gene.
Br. J. Pharmacol.143: 590-598 (2004).
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Barancik M, Bohacova V, Sedlak J, Sulova Z, Breier A. LY294,002, a specific inhibitor of PI3K/Akt kinase pathway, antagonizes P-glycoprotein-mediated multidrug resistance.
Eur. J. Pharm. Sci. 29: 426-434 (2006).
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Barash H, R Gross E, Edrei Y, Ella E, Israel A, Cohen I, Corchia N, Ben-Moshe T, Pappo O, Pikarsky E, Goldenberg D, Shiloh Y, Galun E, Abramovitch R. Accelerated carcinogenesis following liver regeneration is associated with chronic inflammation-induced double-strand DNA breaks.
Proc. Natl. Acad. Sci. U.S.A. 107: 2207-2212 (2010).
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Barnes SN, Aleksunes LM, Augustine L, Scheffer GL, Goedken M, Jakowski AB, Pruimboom-Brees IM, Cherrington NJ, Manautou JE. Induction of hepatobiliary efflux transporters in acetaminophen-induced acute liver failure cases.
Drug Metab. Dispos. 35: 1963-1969 (2007).
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Barrie A, Regueiro M. Biologic therapy in the management of extraintestinal manifestations of inflammatory bowel disease.
Inflamm. Bowel Dis. 13: 1424-1429 (2007).
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Bartels AL, van Berckel BN, Lubberink M, Luurtsema G, Lammertsma AA, Leenders KL. Blood-brain barrier P-glycoprotein function is not impaired in early Parkinson's disease.
Parkinsonism Relat. Disord. 14: 505-508 (2008).
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Barth A, Braun J, Muller D. Influence of verapamil and cyclosporin A on bile acid metabolism and transport in rat liver slices.
Exp. Toxicol. Pathol. 58: 31-37 (2006).
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Bartnicka L, Kurzawski M, Drozdzik A, Plonska-Gosciniak E, Gornik W, Drozdzik M. Effect of ABCB1 (MDR1) 3435C >T and 2677G >A,T polymorphisms and P-glycoprotein inhibitors on salivary digoxin secretion in congestive heart failure patients.
Pharmacol. Rep. 59: 323-329 (2007).
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Bartolini G, Orlandi M, Papi A, Ammar K, Guerra F, Ferreri AM, Rocchi P. A search for multidrug resistance modulators: the effects of retinoids in human colon carcinoma cells.
In Vivo 20: 729-733 (2006).
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Basic S, Hajnsek S, Poljakovic Z, Basic M. Lack of association between the C3435T polymorphism in the human multidrug resistance (MDR1) gene and response to antiepileptic drug treatment.
Epilepsia 47: 449 (2006).
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Bassi C, Xavier Dj, Palomino G, Nicolucci P, Soares C, Sakamoto-Hojo E, Donadi E. Efficiency of the DNA repair and polymorphisms of the XRCC1, XRCC3 and XRCC4 DNA repair genes in systemic lupus erythematosus.
Lupus 17: 988-995 (2008).
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Bastone L, Reilly M, Rader DJ, Foulkes AS. MDR and PRP: a comparison of methods for high-order genotype-phenotype associations.
Hum. Hered. 58: 82-92 (2004).
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Batrakova EV, Kelly DL, Li S, Li Y, Yang Z, Xiao L, Alakhova DY, Sherman S, Alakhov VY, Kabanov AV. Alteration of genomic responses to doxorubicin and prevention of MDR in breast cancer cells by a polymer excipient: pluronic P85.
Mol. Pharm. 3: 113-123 (2006).
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Bauer B, Hartz AM, Lucking JR, Yang X, Pollack GM, Miller DS. Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier.
J. Cereb. Blood Flow Metab. 28: 1222-1234 (2008).
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Beck K, Hayashi K, Dang K, Hayashi M, Boyd CD. Analysis of ABCC6 (MRP6) in normal human tissues.
Histochem. Cell. Biol. 123: 517-528 (2005).
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Becquemont L, Camus M, Kriaa F, Barbu V, Charpentier B, Jaillon P. Low levels of lymphocyte MDR1 gene expression during early renal transplantation in patients treated with tacrolimus.
Fundam. Clin. Pharmacol. 14: 225-229 (2000).
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Becquemont L, Glaeser H, Drescher S, Hitzl M, Simon N, Murdter TE, Heinkele G, Hofmann U, Schaefer C, Burk O, Verstuyft C, Eichelbaum M, Fromm MF. Effects of ursodeoxycholic acid on P-glycoprotein and cytochrome P450 3A4-dependent pharmacokinetics in humans.
Clin. Pharmacol. Ther. 79: 449-460 (2006).
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Beedholm-Ebsen R, van de Wetering K, Hardlei T, Nexo E, Borst P, Moestrup SK. Identification of multidrug resistance protein 1 (MRP1/ABCC1) as a molecular gate for cellular export of cobalamin.
Blood Nov 6 [Epub ahead of print] (2009).
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Beilke LD, Besselsen DG, Cheng Q, Kulkarni S, Slitt AL, Cherrington NJ. Minimal role of hepatic transporters in the hepatoprotection against LCA-induced intrahepatic cholestasis.
Toxicol. Sci. 102: 196-204 (2008).
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Beketic-Oreskovic L, Duran GE, Chen G, Dumontet C, Sikic BI. Decreased mutation rate for cellular resistance to doxorubicin and suppression of mdr1 gene activation by the cyclosporin PSC 833.
J. Natl. Cancer Inst. 87: 1593-1602 (1995).
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Belinsky MG, Dawson PA, Shchaveleva I, Bain LJ, Wang R, Ling V, Chen ZS, Grinberg A, Westphal H, Klein-Szanto A, Lerro A, Kruh GD. Analysis of the in vivo functions of Mrp3.
Mol. Pharmacol. 68: 160-168 (2005).
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Belliard AM, Lacour B, Farinotti R, Leroy C. Effect of tumor necrosis factor-alpha and interferon-gamma on intestinal P-glycoprotein expression, activity, and localization in Caco-2 cells.
J. Pharm. Sci. 93: 1524-1536 (2004).
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Benlloch M, Ortega A, Ferrer P, Segarra R, Obrador E, Asensi M, Carretero J, Estrela JM. Acceleration of glutathione efflux and inhibition of gamma-glutamyl transpeptidase sensitize metastatic B16 melanoma cells to endothelium-induced cytotoxicity.
J. Biol. Chem. 280: 6950-6959 (2005).
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Beretta L, Cappiello F, Moore JH, Barili M, Greene CS, Scorza R. Ability of epistatic interactions of cytokine single-nucleotide polymorphisms to predict susceptibility to disease subsets in systemic sclerosis patients.
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David and Judy Rhodes
Last Update: 2/27/2010
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